D:Abdominal Obesity

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Disease Term
Synonyms ABDOMINAL OBESITIES, CENTRAL OBESITIES, Central Obesity, Obesities Abdominal, Obesities Central, Obesity Central
Documents 116
Hot Single Events 93
Hot Interactions 8

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Abdominal Obesity. They are ordered first by their relevance to Abdominal Obesity and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19 94.56
2 INT217665 ADIPOQ Positive_regulation of INS 2 0.06 1.8 0.19 94.12
3 INT306794 Binding of LEP and COPD 1 0.15 3.94 0.09 93.16
4 INT335607 Binding of INS and TGS1 1 0.04 0.95 0 93.04
5 INT217666 ADIPOQ Regulation of Gene_expression of INS 1 0.03 1.99 0.05 91.48
6 INT217667 LEP Negative_regulation of Localization of INS 1 0.15 1.18 0.14 86.88
7 INT217664 LEP Negative_regulation of INS 1 0.15 1.18 0.14 86.88
8 INT258492 Binding of Ins1 and Cdipt 1 0.00 0.92 0 80.96
9 INT172833 Binding of FFAR1 and T2dm2 1 0.00 1.55 0 60.88
10 INT253944 Positive_regulation of Prkca Positive_regulation of Gene_expression of Ins1 1 0.01 1.53 0.35 60.36
11 INT323019 Binding of PTX3 and Crp 1 0.06 1.17 0.13 50.00
12 INT335606 Binding of CISH and LAP 1 0.14 2.21 0 48.36
13 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
14 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4 5.00
15 INT44442 GNRH1 Positive_regulation of Localization of PLOD1 3 0.50 0.78 0.86 5.00
16 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83 5.00
17 INT189671 DAG1 Positive_regulation of PRKCA 3 0.12 0.71 0.82 5.00
18 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77 5.00
19 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69 5.00
20 INT172825 Binding of Crp and T2dm2 1 0.00 4.5 0.62 5.00
21 INT294708 CRP Positive_regulation of Gene_expression of VCAM1 2 0.31 1.92 0.56 5.00
22 INT316546 Binding of GH1 and SST 2 0.03 0.55 0.54 5.00
23 INT194595 Binding of TNFSF10 and TNFRSF10B 4 0.15 9.3 0.53 5.00
24 INT344709 Niacr1 Positive_regulation of Hdl1 1 0.32 2.74 0.46 5.00
25 INT194596 Binding of HLA-DRB4 and TNFSF10 3 0.08 6 0.38 5.00
26 INT303994 Il6 Positive_regulation of JAK2 1 0.03 0.41 0.37 5.00
27 INT303982 Il6 Positive_regulation of STAT3 1 0.03 0.41 0.37 5.00
28 INT316545 Binding of IGF1 and SST 1 0.06 0.45 0.37 5.00
29 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37 5.00
30 INT226785 Angpt2 Positive_regulation of Localization of Lep 1 0.01 1.65 0.36 5.00
31 INT89381 INS Positive_regulation of AKT1 6 0.43 3.06 0.33 5.00
32 INT230855 KNG1 Regulation of NOS1 2 0.03 0.94 0.33 5.00
33 INT303993 Lep Positive_regulation of Gene_expression of IL2 1 0.15 0.24 0.33 5.00
34 INT230852 ACE Regulation of KNG1 2 0.03 0.72 0.32 5.00
35 INT227339 Binding of TNF and Ins1 1 0.28 4.08 0.31 5.00
36 INT172822 Binding of Fga and T2dm2 1 0.01 2.24 0.31 5.00
37 INT303983 Lep Positive_regulation of CXCL10 1 0.06 0.31 0.29 5.00
38 INT303998 Lep Positive_regulation of Localization of IL1RAPL1 1 0.04 0.31 0.29 5.00
39 INT303995 Lep Positive_regulation of PSME1 1 0.09 0.32 0.29 5.00
40 INT303949 LEPR Positive_regulation of SOAT1 1 0.01 0.22 0.28 5.00
41 INT303984 Lep Positive_regulation of Gene_expression of IL8 1 0.06 0.85 0.28 5.00
42 INT344704 Positive_regulation of Ppara Positive_regulation of Binding of Hdl1 1 0.13 0.83 0.28 5.00
43 INT303948 LEPR Positive_regulation of PIK3CG 1 0.02 0.22 0.28 5.00
44 INT344715 Positive_regulation of Ppara Positive_regulation of Gene_expression of Pltp 1 0.02 0.83 0.28 5.00
45 INT344714 Nr1h4 Negative_regulation of Gene_expression of Lipg 1 0.02 0.77 0.23 5.00
46 INT306795 Binding of LEP and SFTPD 1 0.08 1.13 0.23 5.00
47 INT303988 Lep Positive_regulation of Gene_expression of ISYNA1 1 0.06 0.55 0.23 5.00
48 INT303992 Il1 Positive_regulation of Gene_expression of IL8 1 0.00 0.55 0.23 5.00
49 INT303985 Il1 Positive_regulation of Gene_expression of ISYNA1 1 0.01 0.54 0.23 5.00
50 INT207845 Binding of INS and Hypism 3 0.04 2.88 0.22 5.00
51 INT172826 Binding of Tnfsf4 and T2dm2 1 0.00 5.97 0.22 5.00
52 INT311872 IGHE Positive_regulation of Localization of Mmp9 1 0.01 1.35 0.22 5.00
53 INT304001 Lep Negative_regulation of ICAM3 1 0.07 0.35 0.2 5.00
54 INT303979 Lep Positive_regulation of ITGB2 1 0.11 0.35 0.2 5.00
55 INT303991 Lep Negative_regulation of SELL 1 0.04 0.35 0.2 5.00
56 INT303964 Lep Positive_regulation of Icam1 1 0.24 0.35 0.19 5.00
57 INT303981 Lep Positive_regulation of Localization of CXCL1 1 0.02 0.34 0.18 5.00
58 INT172829 Binding of Nfkb1 and ISYNA1 1 0.00 2.06 0.17 5.00
59 INT172820 Binding of Nfkb1 and T2dm2 1 0.00 2.14 0.17 5.00
60 INT303967 Lep Positive_regulation of Gene_expression of Icam1 1 0.24 0.58 0.16 5.00
61 INT303980 Lep Positive_regulation of Transcription of IL2 1 0.10 0.24 0.16 5.00
62 INT172827 ROS1 Positive_regulation of Tnf 1 0.01 2.1 0.16 5.00
63 INT172837 ROS1 Positive_regulation of Nfkb1 1 0.00 2.11 0.16 5.00
64 INT344721 Binding of AHA and Hdl1 1 0.02 1.16 0.15 5.00
65 INT332285 Binding of KLRD1 and CRLF1 1 0.00 1.71 0.14 5.00
66 INT344707 Scarb1 Positive_regulation of Positive_regulation of Hdl1 1 0.14 0.88 0.14 5.00
67 INT344710 Lipc Positive_regulation of Positive_regulation of Hdl1 1 0.04 0.87 0.14 5.00
68 INT239317 Egfl7 Positive_regulation of Hdl1 2 0.01 2.3 0.14 5.00
69 INT321408 INS Positive_regulation of EGR1 1 0.03 2.36 0.13 5.00
70 INT321414 INS Positive_regulation of Transcription of EGR1 1 0.03 2.36 0.13 5.00
71 INT344705 Nr1h2 Regulation of Scarb1 1 0.04 1.53 0.12 5.00
72 INT344706 Nr1h2 Regulation of Abca1 1 0.03 2.39 0.12 5.00
73 INT321404 Positive_regulation of MAP3K5 Positive_regulation of Gene_expression of SERPINE1 1 0.02 2.2 0.12 5.00
74 INT321410 EGR1 Negative_regulation of Gene_expression of TNFSF10 1 0.10 2.07 0.12 5.00
75 INT307698 Binding of Crp and pad 1 0.04 3.71 0.12 5.00
76 INT344713 Nr1h2 Regulation of Abcg1 1 0.03 2.39 0.12 5.00
77 INT172824 Positive_regulation of Binding of Tnfsf4 and T2dm2 1 0.00 2.97 0.12 5.00
78 INT311871 Cav1 Regulation of Mch 1 0.01 0.24 0.11 5.00
79 INT270746 INS Regulation of LEP 1 0.07 0.72 0.11 5.00
80 INT303989 Lep Positive_regulation of IL12A 1 0.05 0.39 0.11 5.00
81 INT303990 Binding of Lep and Positive_regulation of Gene_expression of LPL 1 0.03 0.35 0.1 5.00
82 INT284552 Binding of Cd8a and Mthfd1 2 0.03 1.32 0.1 5.00
83 INT172816 Crp Positive_regulation of Transcription of Nos3 1 0.06 0.91 0.1 5.00
84 INT172817 Crp Positive_regulation of Regulation of Nos3 1 0.09 0.84 0.1 5.00
85 INT246478 Binding of SERPINE1 and ANGPTL5 1 0.01 1.32 0.1 5.00
86 INT172818 Binding of T2dm2 and Hypism 1 0.00 3.62 0.1 5.00
87 INT303966 Lep Regulation of Il1 2 0.09 0.41 0.1 5.00
88 INT172819 Crp Positive_regulation of Gene_expression of Nos3 1 0.06 0.91 0.1 5.00
89 INT172821 Crp Positive_regulation of Negative_regulation of Nos3 1 0.06 0.84 0.1 5.00
90 INT304000 Lep Negative_regulation of Positive_regulation of CASP8 1 0.04 0.25 0.1 5.00
91 INT316543 GH1 Regulation of Gene_expression of IGF1 1 0.03 1.32 0.09 5.00
92 INT316552 Binding of SST and Sst1 1 0.03 0.53 0.09 5.00
93 INT230857 Negative_regulation of Binding of HSP90AA1 and NOS1 1 0.05 1.18 0.09 5.00
94 INT282102 Binding of Crp and Vcam1 1 0.00 1.55 0.09 5.00
95 INT267156 Binding of VDR and SUGT1 1 0.04 3.4 0.09 5.00
96 INT230856 Binding of HSP90AA1 and NOS1 1 0.04 1.17 0.09 5.00
97 INT172836 Binding of INS and T2dm2 1 0.00 1.65 0.08 5.00
98 INT303999 Lep Positive_regulation of Gene_expression of ITGA2 1 0.06 0.29 0.08 5.00
99 INT332287 LEP Positive_regulation of Phosphorylation of IRS1 1 0.20 1.48 0.08 5.00
100 INT267154 ADIPOQ Regulation of Positive_regulation of SUGT1 1 0.03 1.18 0.08 5.00
101 INT272774 Binding of Mc4r and Fto 1 0.30 0.66 0.08 5.00
102 INT303970 Lep Positive_regulation of Gene_expression of Itga2 1 0.09 0.29 0.08 5.00
103 INT230853 Binding of SELE and VWF 1 0.06 1.3 0.07 5.00
104 INT303997 IL1RL1 Positive_regulation of Lep 1 0.01 0.2 0.07 5.00
105 INT226787 Trglyd Positive_regulation of Lbp 1 0.04 1.67 0.07 5.00
106 INT226786 Scl1 Positive_regulation of Lbp 1 0.04 1.68 0.07 5.00
107 INT213261 TNF Positive_regulation of CRP 1 0.24 1.59 0.06 5.00
108 INT321399 Positive_regulation of SETD7 Positive_regulation of SETDB1 1 0.00 1.25 0.06 5.00
109 INT267152 Binding of LEP and DDX12P 1 0.00 0.69 0.05 5.00
110 INT344719 Hdl1 Positive_regulation of Plat 1 0.10 1.23 0.05 5.00
111 INT267157 LEP Positive_regulation of ADIPOQ 1 0.10 0.51 0.05 5.00
112 INT198620 CRH Negative_regulation of GH1 1 0.05 0.47 0.05 5.00
113 INT198619 CRH Negative_regulation of TRH 1 0.18 0.47 0.05 5.00
114 INT267158 Binding of IRS1 and SHMT2 1 0.02 0.46 0.05 5.00
115 INT345966 Binding of Arid1a and al44 1 0.00 1.56 0.05 5.00
116 INT344703 Hdl1 Negative_regulation of Gene_expression of Serpine1 1 0.07 1.26 0.05 5.00
117 INT198618 CRH Negative_regulation of Localization of SST 1 0.07 0.53 0.05 5.00
118 INT345965 Binding of Lep and al44 1 0.01 1.43 0.05 5.00
119 INT321401 Gene_expression of ROS1 Negative_regulation of Positive_regulation of AKR1B1 1 0.01 0.8 0.05 5.00
120 INT267153 Binding of LEP and SUGT1 1 0.02 0.69 0.05 5.00
121 INT323056 LDLR Regulation of HSD11B1 1 0.01 1.2 0.05 5.00
122 INT213263 INS Positive_regulation of EDN1 1 0.12 0.54 0.04 5.00
123 INT303986 Lep Positive_regulation of Gene_expression of TNF 1 0.49 0.29 0.04 5.00
124 INT207846 Hypism Regulation of INS 1 0.06 1.14 0.04 5.00
125 INT267155 Binding of INS and SUGT1 1 0.02 0.81 0.04 5.00
126 INT303996 Lep Positive_regulation of Gene_expression of IL12A 1 0.08 0.29 0.04 5.00
127 INT89384 Negative_regulation of INS Positive_regulation of AKT1 2 0.36 1.37 0.04 5.00
128 INT303965 Lep Positive_regulation of Gene_expression of Il6 1 0.07 0.29 0.04 5.00
129 INT230854 INS Regulation of Positive_regulation of SNAP47 1 0.09 1.03 0.03 5.00
130 INT230851 INS Regulation of VCAM1 1 0.07 1.02 0.03 5.00
131 INT332286 PIK3CD Positive_regulation of MTOR 1 0.14 0.73 0.03 5.00
132 INT334918 GNRH1 Positive_regulation of Gene_expression of FSHR 2 0.11 1.27 0.03 5.00
133 INT321407 EDN1 Positive_regulation of Phosphorylation of IRS1 1 0.06 1.07 0.03 5.00
134 INT213262 IL6 Positive_regulation of CYP19A1 1 0.11 1.63 0.03 5.00
135 INT172832 Binding of ROS1 and Renbp 1 0.00 0.83 0.03 5.00
136 INT332284 IRS1 Regulation of PIK3CD 1 0.15 0.72 0.03 5.00
137 INT321402 Binding of NPHS1 and PIK3CD 1 0.02 0.73 0.03 5.00
138 INT311870 Positive_regulation of Binding of Cd8a and Mthfd1 1 0.00 0.32 0.03 5.00
139 INT321412 ABCC8 Positive_regulation of Gene_expression of SELE 1 0.00 1.18 0.03 5.00
140 INT246480 Binding of ALB and SHBG 2 0.14 1.45 0.03 5.00
141 INT321405 AGT Positive_regulation of MAPK8 1 0.00 0.94 0.03 5.00
142 INT332288 Positive_regulation of IRS1 Regulation of PIK3CD 1 0.07 0.73 0.03 5.00
143 INT321398 SETD7 Positive_regulation of SETDB1 1 0.00 0.62 0.03 5.00
144 INT340502 Agtr1a Negative_regulation of Phosphorylation of Jak2 1 0.12 2.32 0 5.00
145 INT321406 VEGFA Regulation of BCL2 1 0.01 0.75 0 5.00
146 INT344708 Hdl1 Positive_regulation of Gene_expression of Plat 1 0.08 1.26 0 5.00
147 INT334921 GNRHR Positive_regulation of Gene_expression of CGA 1 0.01 0.53 0 5.00
148 INT172759 INS Positive_regulation of Localization of REN 1 0.03 0.64 0 5.00
149 INT344720 Niacr1 Negative_regulation of Binding of Hdl1 1 0.17 1.13 0 5.00
150 INT340504 Agtr1a Negative_regulation of Phosphorylation of Pik3cb 1 0.06 1.16 0 5.00
151 INT321400 VEGFA Negative_regulation of Gene_expression of BAX 1 0.03 0.75 0 5.00
152 INT334922 GNRHR Positive_regulation of Gene_expression of PLOD1 1 0.08 0.53 0 5.00
153 INT334919 GNRH1 Positive_regulation of Gene_expression of CGA 1 0.03 0.52 0 5.00
154 INT344722 Binding of Lig3 and Chdh 1 0.00 1.48 0 5.00
155 INT303963 Lep Positive_regulation of Gene_expression of Il7 1 0.02 0.41 0 5.00
156 INT172838 Binding of ISL1 and T2dm2 1 0.00 2.41 0 5.00
157 INT172831 Binding of INS and Tnfsf4 1 0.02 1.07 0 5.00
158 INT227399 Binding of D5Mit424 and Alms1 1 0.01 0.71 0 5.00
159 INT334917 GNRHR Positive_regulation of Gene_expression of FSHR 1 0.05 0.53 0 5.00
160 INT172830 INS Positive_regulation of Agtrap 1 0.01 1.17 0 5.00
161 INT344711 Nr1h3 Regulation of Abcg1 1 0.03 1.67 0 5.00
162 INT344717 Binding of Niacr1 and Hdl1 1 0.17 1.51 0 5.00
163 INT311816 CD79A Positive_regulation of RAB27A 1 0.01 0.47 0 5.00
164 INT344723 Niacr1 Positive_regulation of Binding of APOB 1 0.31 1.05 0 5.00
165 INT172839 Binding of ANGPT2 and T2dm2 1 0.00 1.72 0 5.00
166 INT303947 Binding of LEPR and TXK 1 0.00 0.63 0 5.00
167 INT213264 INS Positive_regulation of Localization of IGF1 1 0.16 1.77 0 5.00
168 INT253945 Adrm1 Negative_regulation of Hdl1 1 0.00 1.18 0 5.00
169 INT344712 Nr1h3 Regulation of Abca1 1 0.03 1.68 0 5.00
170 INT344716 Binding of Hdl1 and Chdh 1 0.03 3.24 0 5.00
171 INT303987 Binding of LEPR and Fyn 1 0.02 0.62 0 5.00
172 INT356349 Ins1 Positive_regulation of Lpl 1 0.10 0.45 0 5.00
173 INT172828 Iapp Positive_regulation of Localization of REN 1 0.02 0.64 0 5.00
174 INT172835 Binding of AGT and T2dm2 1 0.00 1.73 0 5.00
175 INT334920 GNRH1 Positive_regulation of Gene_expression of PLOD1 1 0.16 0.52 0 5.00
176 INT227398 Binding of H2afy and Alms1 1 0.01 1.42 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Abdominal Obesity. They are ordered first by their pain relevance and then by number of times they were reported in Abdominal Obesity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT182787 Binding of ETV3 14 0.37 25.44 0.37 100.00
2 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 100.00
3 INT7475 Positive_regulation of Hdl1 138 0.67 175.81 15.05 100.00
4 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04 100.00
5 INT3866 Positive_regulation of Positive_regulation of INS 30 0.59 21.58 1.86 100.00
6 INT259032 Binding of PEX1 2 0.01 4.67 0.15 100.00
7 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.96
8 INT139804 Binding of PTX3 6 0.48 7.42 1.21 99.96
9 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 99.92
10 INT8747 Positive_regulation of Ins1 221 0.69 154.28 35.15 99.88
11 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95 99.88
12 INT17086 Binding of HSD11B1 84 0.47 122.28 6.16 99.88
13 INT139803 Gene_expression of PTX3 22 0.75 26.21 5.07 99.80
14 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 99.80
15 INT10171 Binding of Gtf3a 33 0.36 19.84 5.1 99.80
16 INT182788 Gene_expression of ETV3 8 0.40 11.33 0.36 99.76
17 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56 99.74
18 INT323017 Regulation of Gene_expression of PTX3 1 0.44 4.31 0 99.72
19 INT139805 Positive_regulation of PTX3 15 0.70 14.84 2.71 99.68
20 INT162636 Localization of PTX3 8 0.78 9.73 1.77 99.66
21 INT37800 Positive_regulation of Apob 7 0.18 11.01 0.48 99.60
22 INT1893 Localization of Gh 1041 0.79 340.23 256.58 99.58
23 INT182800 Positive_regulation of ETV3 5 0.46 10.01 0.14 99.56
24 INT21805 Negative_regulation of Hdlbp 7 0.30 9.66 1.43 99.00
25 INT1530 Regulation of Gh 382 0.61 115.96 112.47 98.60
26 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21 98.52
27 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32 98.50
28 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 98.40
29 INT6110 Negative_regulation of Gene_expression of Ins1 83 0.56 60.59 16.07 98.40
30 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 98.24
31 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 97.96
32 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 97.84
33 INT207565 Negative_regulation of LIPG 8 0.10 7.83 0.76 97.44
34 INT812 Localization of INS 1026 0.81 515.6 145.31 96.96
35 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 96.88
36 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 96.72
37 INT65489 Regulation of Gene_expression of Crp 28 0.59 29.17 7.56 96.72
38 INT2275 Negative_regulation of Localization of Ins1 183 0.59 51.02 44.94 96.24
39 INT15918 Gene_expression of Serpine1 60 0.62 41.73 7.72 96.08
40 INT58015 Regulation of Gene_expression of Serpine1 3 0.41 2.61 0.47 96.08
41 INT171251 Regulation of BMI1 8 0.20 10.46 2.01 95.28
42 INT323018 Regulation of PTX3 1 0.27 6.86 1.59 95.16
43 INT1114 Localization of Ins1 748 0.80 192.95 165.48 94.44
44 INT84909 Positive_regulation of SUGT1 22 0.08 22.01 5.43 92.72
45 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 92.64
46 INT122561 Negative_regulation of Gene_expression of Adipoq 12 0.56 14.02 2.26 92.52
47 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58 92.52
48 INT15921 Positive_regulation of Serpine1 85 0.68 81.24 13.4 91.72
49 INT65498 Positive_regulation of F7 4 0.11 8.51 0.79 91.72
50 INT65494 Positive_regulation of Positive_regulation of F7 2 0.08 2.66 0.28 91.72
51 INT5096 Positive_regulation of Gtf3a 79 0.60 42.26 20.62 91.54
52 INT331744 Positive_regulation of Fat1 10 0.15 4.86 0.03 91.52
53 INT270747 Negative_regulation of ETV3 2 0.10 2.91 0.04 90.40
54 INT331745 Binding of Fat1 2 0.08 1.58 0.06 90.24
55 INT2613 Negative_regulation of Positive_regulation of Ren 16 0.59 8.2 5.62 90.08
56 INT14572 Binding of INS 205 0.48 175.43 13.38 90.04
57 INT39639 Gene_expression of F7 3 0.17 2.64 0.2 90.00
58 INT191778 Positive_regulation of Gene_expression of F7 2 0.01 2.76 0.14 90.00
59 INT26975 Gene_expression of Adipoq 113 0.75 106.71 14.46 89.72
60 INT140858 Negative_regulation of SUGT1 9 0.05 8.41 1.4 89.52
61 INT15922 Positive_regulation of Positive_regulation of Serpine1 6 0.31 8.34 2.16 89.40
62 INT227273 Localization of Adipoq 22 0.72 18.04 1.72 89.16
63 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 88.96
64 INT80686 Positive_regulation of Positive_regulation of MAPK8 42 0.68 26.95 7.63 88.96
65 INT352530 Positive_regulation of Positive_regulation of SOCS3 1 0.15 1.77 0.08 88.96
66 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 88.80
67 INT227275 Negative_regulation of Gene_expression of Adipoq 19 0.53 19.51 1.15 88.24
68 INT2560 Gene_expression of Nr2e1 2 0.53 2.5 0.16 88.00
69 INT314 Positive_regulation of Ren 212 0.70 66.68 55.56 87.40
70 INT7678 Localization of Alb 142 0.81 80.93 22.49 87.32
71 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 87.32
72 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 86.96
73 INT80690 Positive_regulation of MAPK8 223 0.68 125.63 36.75 86.80
74 INT179887 Positive_regulation of SOCS3 10 0.50 13.06 0.45 86.80
75 INT15920 Regulation of Serpine1 34 0.42 17.36 4.89 86.16
76 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 86.08
77 INT345951 Negative_regulation of Arid1a 1 0.10 6.11 0.33 86.00
78 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 85.88
79 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5 85.80
80 INT246856 Gene_expression of SPAG8 1 0.75 7.8 1.39 85.48
81 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45 84.40
82 INT251 Regulation of INS 398 0.62 232.47 55.04 84.00
83 INT67612 Binding of PPARG 38 0.48 22.67 8.94 83.80
84 INT334924 Binding of MEHMO 1 0.01 9.69 0.26 83.64
85 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 83.56
86 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 83.56
87 INT261193 Binding of Niacr1 7 0.42 3.6 0.03 83.32
88 INT344689 Negative_regulation of Binding of Niacr1 1 0.24 1.75 0 83.32
89 INT344694 Positive_regulation of Binding of Niacr1 1 0.28 1.91 0 83.32
90 INT165623 Gene_expression of TGS1 5 0.22 3.42 0.13 81.64
91 INT163361 Negative_regulation of SAMSN1 2 0.42 6.6 0.43 81.32
92 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75 80.96
93 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 80.08
94 INT83119 Negative_regulation of Gene_expression of IL12A 24 0.42 17.52 5.69 79.88
95 INT4421 Positive_regulation of LAP 12 0.44 11.06 1.74 79.80
96 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 79.40
97 INT344693 Positive_regulation of Negative_regulation of Chdh 1 0.05 1.76 0 79.12
98 INT344683 Positive_regulation of Negative_regulation of Niacr1 1 0.28 1.77 0 79.12
99 INT116848 Negative_regulation of Chdh 10 0.42 19.68 1.95 78.60
100 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31 78.32
101 INT294370 Negative_regulation of Niacr1 3 0.24 2.54 0.42 78.20
102 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 77.80
103 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 77.80
104 INT323016 Positive_regulation of Positive_regulation of PTX3 1 0.45 1.41 0.04 77.52
105 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 76.60
106 INT166021 Positive_regulation of MCL1 36 0.67 62.97 1.44 75.24
107 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66 74.08
108 INT23010 Positive_regulation of CYP19A1 28 0.58 24.18 5.37 73.56
109 INT97443 Positive_regulation of Positive_regulation of LEP 13 0.50 11.91 2.65 73.56
110 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 73.52
111 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 73.52
112 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 73.52
113 INT1472 Positive_regulation of Ins1 349 0.69 146.2 86.36 72.96
114 INT66227 Gene_expression of COX18 41 0.50 26.91 6.26 72.36
115 INT187411 Gene_expression of Cd320 23 0.75 12.1 1.39 71.48
116 INT159425 Positive_regulation of Cd320 11 0.67 9.35 0.11 71.48
117 INT77249 Positive_regulation of Gene_expression of gr 24 0.67 16.09 8.17 71.16
118 INT77250 Positive_regulation of Gene_expression of Nr3c1 4 0.44 3.32 2.64 71.16
119 INT32458 Gene_expression of VWF 57 0.78 28.97 5.56 70.80
120 INT17996 Binding of Crp 40 0.37 31.4 7.8 70.80
121 INT13995 Gene_expression of gr 96 0.74 48.21 26.54 70.76
122 INT77252 Gene_expression of Nr3c1 17 0.67 9.71 5.38 70.76
123 INT19392 Gene_expression of Ada 9 0.77 7.4 3.17 70.48
124 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22 69.84
125 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17 69.84
126 INT39415 Gene_expression of HBN1 33 0.43 19.31 0.93 69.24
127 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 68.80
128 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61 68.80
129 INT18773 Localization of ALB 117 0.80 69.18 13.8 68.80
130 INT142626 Negative_regulation of Localization of ALB 9 0.55 6.63 2.24 68.80
131 INT64888 Negative_regulation of HBM 52 0.16 34.33 5.45 67.56
132 INT39518 Negative_regulation of HBN1 66 0.09 37.54 2.58 67.56
133 INT74520 Positive_regulation of CD68 30 0.61 31.68 7.59 67.52
134 INT28269 Negative_regulation of Adp 18 0.36 5.98 4.74 67.12
135 INT66318 Gene_expression of NR3C1 26 0.76 20 7.55 67.08
136 INT8340 Negative_regulation of SHBG 49 0.57 35.96 4.73 66.32
137 INT4146 Binding of SHBG 49 0.47 31 4.71 66.32
138 INT246851 Negative_regulation of Gene_expression of H6PD 1 0.02 2.67 0.33 66.32
139 INT194343 Gene_expression of ABCC8 8 0.65 8.15 0.77 66.28
140 INT15109 Gene_expression of H6PD 9 0.65 7.21 0.93 65.80
141 INT172793 Positive_regulation of Negative_regulation of Adp 1 0.02 0.99 0.05 65.68
142 INT45079 Binding of Ahr 21 0.44 10.07 1 64.20
143 INT17574 Binding of CISH 23 0.31 4.3 0.93 64.00
144 INT331747 Localization of Fat1 3 0.16 1.91 0.03 63.56
145 INT75907 Binding of LEP 53 0.46 46.65 8.44 62.16
146 INT7113 Negative_regulation of Localization of CGA 71 0.51 17.7 23.42 59.84
147 INT443 Localization of POMC 1020 0.81 284.52 443.17 59.84
148 INT327715 Binding of CNC 1 0.07 1.21 0.07 59.64
149 INT1793 Localization of CGA 379 0.81 67.38 114.69 59.48
150 INT59150 Gene_expression of Sbp 6 0.58 2.4 1.33 58.96
151 INT26996 Positive_regulation of Gene_expression of Crp 21 0.68 21.55 2.75 58.92
152 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91 58.72
153 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 58.52
154 INT96338 Gene_expression of HPSE 17 0.75 18.71 2.73 57.40
155 INT16608 Positive_regulation of FFAR1 40 0.37 18.48 3.59 56.72
156 INT246854 Positive_regulation of Negative_regulation of SPAG8 1 0.49 0.86 0.05 56.60
157 INT246859 Negative_regulation of Negative_regulation of SPAG8 1 0.41 0.75 0.05 56.60
158 INT236152 Negative_regulation of SPAG8 2 0.41 2.24 0.05 56.60
159 INT164587 Gene_expression of MCL1 94 0.75 124.05 5.39 56.20
160 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38 55.44
161 INT189169 Positive_regulation of MTNR1B 10 0.16 3.71 1.61 55.44
162 INT250219 Positive_regulation of KCNJ11 3 0.68 2.5 0.12 55.44
163 INT300140 Positive_regulation of CAMK1D 1 0.16 1.24 0.07 55.44
164 INT300138 Positive_regulation of FTO 2 0.36 2.64 0.07 55.44
165 INT300139 Positive_regulation of WFS1 1 0.36 1.32 0.07 55.44
166 INT300142 Positive_regulation of NOTCH2 1 0.16 1.26 0.07 55.44
167 INT268683 Positive_regulation of JAZF1 2 0.34 2.85 0.07 55.44
168 INT245191 Positive_regulation of TCF7L2 2 0.46 1.54 0.07 55.44
169 INT300143 Positive_regulation of TSPAN8 1 0.17 1.26 0.07 55.44
170 INT300136 Positive_regulation of SLC30A8 1 0.15 1.26 0.07 55.44
171 INT300141 Positive_regulation of THADA 1 0.16 1.26 0.07 55.44
172 INT300144 Positive_regulation of IGF2BP2 1 0.16 1.25 0.07 55.44
173 INT300137 Positive_regulation of HNF1B 1 0.16 1.25 0.07 55.44
174 INT74250 Negative_regulation of Gene_expression of Ins1 47 0.40 39.27 5.37 54.88
175 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 54.76
176 INT31582 Gene_expression of Hdl1 103 0.66 118.95 6.42 54.72
177 INT330708 Negative_regulation of Ccndbp1 1 0.01 0.68 0.03 54.60
178 INT94454 Gene_expression of CD68 73 0.72 63.94 10.43 54.40
179 INT52940 Gene_expression of PILRA 2 0.22 1.67 0.25 54.40
180 INT261192 Gene_expression of Niacr1 57 0.67 24.37 1.89 52.80
181 INT331748 Positive_regulation of Positive_regulation of Fat1 1 0.11 1.26 0 52.60
182 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 52.44
183 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 52.16
184 INT326 Gene_expression of Gnrhr 105 0.76 35.87 34.93 52.12
185 INT352531 Regulation of Gene_expression of CD68 1 0.51 5.59 0.72 51.16
186 INT28539 Binding of Etv3 7 0.21 3.83 0.74 51.00
187 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 50.28
188 INT12082 Localization of IL6 365 0.81 241.78 105.78 50.00
189 INT106745 Localization of CRP 65 0.81 66.44 15.21 50.00
190 INT162635 Positive_regulation of Localization of PTX3 2 0.49 4.86 0.78 50.00
191 INT288903 Positive_regulation of Gene_expression of PTX3 2 0.67 1.47 0.43 50.00
192 INT9649 Positive_regulation of LPA 105 0.69 74.75 13.89 49.48
193 INT74614 Positive_regulation of Apoa1 16 0.68 23.95 5.04 49.48
194 INT40877 Positive_regulation of APOB 35 0.68 32.47 1.86 49.48
195 INT75908 Regulation of LEP 77 0.60 60.16 15.19 49.08
196 INT119606 Regulation of Gene_expression of LEP 17 0.45 17.96 3.75 49.08
197 INT89394 Phosphorylation of INS 37 0.82 35.84 3.9 48.96
198 INT213272 Negative_regulation of Phosphorylation of INS 7 0.40 9.13 0.44 48.96
199 INT1631 Binding of Hdl1 42 0.36 49.22 2.92 47.24
200 INT344691 Negative_regulation of Binding of Hdl1 2 0.31 2.95 0.19 47.24
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