D:Abruptio Placentae

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Disease Term
Synonyms Abruption Placental, Abruptions Placental, Placental Abruption, Placental Abruptions
Documents 140
Hot Single Events 30
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Abruptio Placentae. They are ordered first by their relevance to Abruptio Placentae and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT175246 Binding of F13A1 and SH2B2 1 0.00 2.24 0 92.44
2 INT302469 F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.82 0.62 80.00
3 INT302468 INCENP Positive_regulation of Gene_expression of MMP9 1 0.01 0.72 0.26 80.00
4 INT260897 CRH Positive_regulation of Localization of IL8 1 0.24 0.09 1.51 5.00
5 INT260894 CRH Regulation of Localization of MMP3 1 0.21 0.36 0.85 5.00
6 INT260895 CRH Regulation of MMP1 1 0.11 0.31 0.74 5.00
7 INT175323 Tlr4 Positive_regulation of Gene_expression of TLR2 1 0.02 0.31 0.56 5.00
8 INT175326 SERPINH1 Regulation of Pnlip 1 0.00 0.53 0.49 5.00
9 INT302466 Positive_regulation of F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.1 0.35 5.00
10 INT175319 Negative_regulation of Nos2 Negative_regulation of Positive_regulation of Pnlip 1 0.01 0.83 0.34 5.00
11 INT260893 CRH Positive_regulation of Gene_expression of IL8 1 0.28 0.05 0.31 5.00
12 INT260896 CRH Positive_regulation of Localization of MMP9 1 0.15 0.15 0.3 5.00
13 INT302467 TIMP1 Positive_regulation of Negative_regulation of COL5A2 1 0.00 1.1 0.29 5.00
14 INT175321 IL6 Positive_regulation of Localization of Oxt 1 0.01 0.7 0.25 5.00
15 INT175322 Oxt Positive_regulation of Gene_expression of PTGER2 1 0.00 0.09 0.25 5.00
16 INT175324 Hsp90b1 Positive_regulation of TLR2 1 0.00 0.65 0.23 5.00
17 INT175317 Hsp90b1 Positive_regulation of Tlr4 1 0.02 0.66 0.23 5.00
18 INT175320 Tlr4 Positive_regulation of Gene_expression of Mmp9 1 0.01 0.54 0.21 5.00
19 INT175325 Binding of TLR2 and Tlr6 1 0.00 0.39 0.09 5.00
20 INT175327 Binding of TLR2 and Tlr1 1 0.00 0.39 0.09 5.00
21 INT143067 Mthfd1 Positive_regulation of Serpine1 1 0.00 0 0 5.00
22 INT143066 Mthfd1 Regulation of Gene_expression of Plau 1 0.00 0 0 5.00
23 INT143065 Mthfd1 Positive_regulation of Gene_expression of Serpine1 1 0.00 0 0 5.00
24 INT143078 PAQR8 Negative_regulation of Gene_expression of Plau 1 0.00 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Abruptio Placentae. They are ordered first by their pain relevance and then by number of times they were reported in Abruptio Placentae. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT81965 Gene_expression of F5 16 0.65 13.29 0.48 99.68
2 INT84180 Binding of F5 22 0.48 18.6 0.49 99.64
3 INT14447 Localization of F2 20 0.79 12.77 2.67 99.28
4 INT185220 Regulation of EBAG9 2 0.27 2.74 0.56 98.04
5 INT119641 Gene_expression of EBAG9 25 0.76 33.2 3.96 98.00
6 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 97.54
7 INT330633 Gene_expression of PROS1 4 0.65 1.54 0.04 96.96
8 INT349254 Negative_regulation of PROS1 1 0.42 1.24 0 96.96
9 INT185222 Regulation of Gene_expression of EBAG9 5 0.60 4.98 0.64 96.80
10 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 96.44
11 INT16631 Negative_regulation of APC 46 0.57 30.53 7.11 96.36
12 INT175260 Negative_regulation of Gene_expression of SH2B2 2 0.25 4.41 0.21 95.72
13 INT102187 Gene_expression of SH2B2 23 0.59 26.54 4.39 95.72
14 INT11183 Negative_regulation of SH2B2 4 0.34 6.99 2.12 95.36
15 INT57057 Gene_expression of APC 131 0.78 122.24 8.7 95.08
16 INT58015 Regulation of Gene_expression of Serpine1 3 0.41 2.61 0.47 93.84
17 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68 93.80
18 INT37661 Negative_regulation of SERPINC1 48 0.59 38.6 4.77 93.80
19 INT12131 Gene_expression of POR 17 0.77 9.42 2.17 93.68
20 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 93.44
21 INT175262 Binding of SH2B2 18 0.36 22.85 3.18 92.44
22 INT15918 Gene_expression of Serpine1 60 0.62 41.73 7.72 92.08
23 INT71116 Gene_expression of Plau 29 0.77 4.94 6.45 91.80
24 INT10513 Gene_expression of Plat 44 0.76 19.49 7.17 91.44
25 INT21900 Gene_expression of Mthfd1 150 0.75 69.47 27.03 91.28
26 INT34796 Positive_regulation of TNFSF14 7 0.67 4.16 2.26 89.00
27 INT250790 Negative_regulation of Localization of APC 2 0.13 2.3 0.13 83.00
28 INT195672 Localization of APC 7 0.74 3.76 0.3 82.44
29 INT73335 Gene_expression of ACTB 21 0.58 5.62 1.94 82.16
30 INT178116 Phosphorylation of GJA1 7 0.80 4.09 0.74 80.08
31 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 80.00
32 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72 80.00
33 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78 80.00
34 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7 80.00
35 INT92823 Positive_regulation of Gene_expression of MMP1 65 0.68 25.69 14.31 80.00
36 INT102237 Positive_regulation of Gene_expression of MMP3 22 0.44 7.77 4.71 80.00
37 INT3546 Binding of Oxt 54 0.48 9.75 10.81 79.76
38 INT53516 Binding of CACNA1A 9 0.47 6.86 3.36 79.44
39 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42 78.48
40 INT26314 Positive_regulation of MMP3 48 0.67 22.14 16.17 77.60
41 INT9842 Binding of F2 36 0.47 22.79 4.42 77.04
42 INT93663 Positive_regulation of MMP1 72 0.67 33.38 19.86 77.04
43 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63 76.56
44 INT173639 Positive_regulation of INCENP 40 0.14 20.97 6.7 76.56
45 INT129703 Negative_regulation of ptd 3 0.37 2.63 1.87 71.44
46 INT175296 Negative_regulation of Pnlip 1 0.08 2.89 0.33 70.80
47 INT4498 Gene_expression of F2 83 0.65 57.4 10.8 70.32
48 INT89217 Negative_regulation of ADAMTS13 8 0.50 12.32 0.51 63.60
49 INT425 Localization of PRL 455 0.81 189.64 144.8 63.60
50 INT185218 Positive_regulation of Gene_expression of EBAG9 1 0.46 0.31 0 60.16
51 INT92248 Negative_regulation of F5 7 0.43 3.28 0.4 57.44
52 INT17283 Positive_regulation of CSF1 37 0.59 24.16 10.01 54.48
53 INT5454 Localization of CRH 124 0.79 79.18 41.53 51.48
54 INT129 Localization of OXTR 51 0.80 11.08 15.36 51.20
55 INT5864 Localization of IL36RN 19 0.44 14.5 6.87 51.20
56 INT937 Positive_regulation of Oxt 195 0.70 37.82 49.3 45.04
57 INT60423 Positive_regulation of TPSG1 11 0.57 11.02 2.55 43.60
58 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 38.72
59 INT7082 Gene_expression of CRH 180 0.78 64.66 31.74 38.72
60 INT119270 Regulation of Fbrs 3 0.53 1.41 0.17 34.64
61 INT225200 Binding of Fbrs 1 0.05 0.43 0.08 31.80
62 INT35584 Binding of ACLY 22 0.35 31.78 7.17 29.80
63 INT145854 Gene_expression of Jak2 4 0.67 3.08 0.41 29.68
64 INT6441 Positive_regulation of CRH 98 0.69 57.22 24.12 26.60
65 INT57502 Positive_regulation of Gene_expression of CRH 30 0.70 23.37 5.7 26.60
66 INT25029 Positive_regulation of Positive_regulation of CRH 7 0.49 6.77 3.52 24.72
67 INT18412 Binding of PLEK 49 0.47 17.82 10.72 23.80
68 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 8.68
69 INT263932 Positive_regulation of PROCR 6 0.67 2.43 0.46 6.92
70 INT73667 Positive_regulation of F5 6 0.60 3.38 0.39 6.92
71 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
72 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
73 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
74 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
75 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 5.00
76 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
77 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 5.00
78 INT12339 Localization of IL8 437 0.81 251.87 117.39 5.00
79 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
80 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
81 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 5.00
82 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 5.00
83 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 5.00
84 INT2893 Localization of Oxt 219 0.80 28.96 79.43 5.00
85 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 5.00
86 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 5.00
87 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 5.00
88 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01 5.00
89 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 5.00
90 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9 5.00
91 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02 5.00
92 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65 5.00
93 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 5.00
94 INT48222 Positive_regulation of Localization of IL8 123 0.59 78.04 37.2 5.00
95 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17 5.00
96 INT927 Gene_expression of Oxt 184 0.78 44.71 35.79 5.00
97 INT104392 Gene_expression of Cxcl10 113 0.75 106.86 34.12 5.00
98 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89 5.00
99 INT99610 Localization of MMP9 126 0.79 48.46 32.67 5.00
100 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 5.00
101 INT90792 Localization of Il10 144 0.80 87.88 30.03 5.00
102 INT52712 Negative_regulation of PRKCA 64 0.57 23.11 28.43 5.00
103 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71 5.00
104 INT1765 Positive_regulation of Gene_expression of PTGER2 140 0.51 68.68 27 5.00
105 INT9647 Gene_expression of PROC 163 0.65 89.76 26.75 5.00
106 INT1761 Positive_regulation of PTGER2 135 0.49 90.17 26.26 5.00
107 INT10836 Negative_regulation of IL8 95 0.59 52.59 24.71 5.00
108 INT34488 Negative_regulation of MMP2 85 0.59 41.98 21.72 5.00
109 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37 5.00
110 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 5.00
111 INT168263 Gene_expression of IL23A 57 0.58 47.1 17.67 5.00
112 INT10834 Binding of IL8 65 0.48 41.66 16.53 5.00
113 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 5.00
114 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 5.00
115 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 5.00
116 INT5333 Gene_expression of NPEPPS 45 0.65 26.34 15.25 5.00
117 INT81486 Localization of MMP3 31 0.81 12.94 15.21 5.00
118 INT103210 Localization of MMP1 43 0.78 12.15 15.13 5.00
119 INT113606 Positive_regulation of Gene_expression of Mmp9 46 0.64 44 15.07 5.00
120 INT74587 Gene_expression of MMP8 31 0.78 24.4 14.91 5.00
121 INT1888 Protein_catabolism of F13A1 97 0.99 63.48 14.82 5.00
122 INT59870 Gene_expression of F3 51 0.65 51.83 14.01 5.00
123 INT16919 Gene_expression of IL36RN 48 0.48 32.78 13.83 5.00
124 INT15011 Positive_regulation of Gpi1 29 0.47 12.47 13.48 5.00
125 INT15921 Positive_regulation of Serpine1 85 0.68 81.24 13.4 5.00
126 INT2673 Negative_regulation of PROC 93 0.57 50.34 12.79 5.00
127 INT5452 Regulation of CRH 56 0.62 15.32 12.42 5.00
128 INT11288 Negative_regulation of CRH 44 0.00 16.69 12.37 5.00
129 INT1708 Gene_expression of OXTR 56 0.78 6.92 10.69 5.00
130 INT133030 Positive_regulation of Gene_expression of TLR2 53 0.65 38.15 10.65 5.00
131 INT150540 Binding of TLR2 50 0.45 35.86 10.43 5.00
132 INT95632 Positive_regulation of MMP8 26 0.70 10.06 9.96 5.00
133 INT10139 Positive_regulation of F13A1 64 0.56 44.75 9.69 5.00
134 INT102987 Regulation of MMP3 23 0.60 9.35 9.54 5.00
135 INT26502 Negative_regulation of Gene_expression of MMP2 39 0.58 21.45 9.42 5.00
136 INT80036 Positive_regulation of FAS 42 0.67 42.22 9.4 5.00
137 INT37896 Positive_regulation of Gene_expression of PTGS1 37 0.67 17.28 9.27 5.00
138 INT9899 Gene_expression of Vwf 91 0.74 45.06 9.13 5.00
139 INT4534 Regulation of PROC 38 0.33 19.81 8.99 5.00
140 INT173587 Protein_catabolism of COL5A2 59 0.32 32.73 8.96 5.00
141 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 5.00
142 INT187190 Positive_regulation of Localization of MMP9 27 0.68 8.1 8.93 5.00
143 INT591 Negative_regulation of Serpinc1 44 0.57 31.73 8.82 5.00
144 INT621 Positive_regulation of SERPINH1 19 0.57 21.52 8.44 5.00
145 INT2271 Gene_expression of F2 51 0.76 30.21 7.97 5.00
146 INT6957 Positive_regulation of OXTR 38 0.70 6.55 7.81 5.00
147 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51 5.00
148 INT8684 Positive_regulation of ANGPTL5 45 0.69 36.29 7.47 5.00
149 INT67822 Binding of SERPINH1 17 0.36 19.05 7.24 5.00
150 INT168600 Binding of Mmp9 14 0.44 12.79 6.92 5.00
151 INT20922 Positive_regulation of Localization of CRH 18 0.67 11.12 6.79 5.00
152 INT168383 Positive_regulation of Mmp13 27 0.67 17.9 6.27 5.00
153 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 5.00
154 INT95607 Regulation of MMP1 19 0.60 7.86 6.18 5.00
155 INT74422 Regulation of Localization of IL8 21 0.62 10.19 5.99 5.00
156 INT103760 Regulation of Gene_expression of Tlr4 35 0.59 16.26 5.95 5.00
157 INT187133 Protein_catabolism of TIMP1 19 0.73 11.3 5.51 5.00
158 INT174851 Positive_regulation of COL5A2 46 0.54 12.73 5.48 5.00
159 INT175312 Positive_regulation of Gene_expression of IL23A 17 0.45 14.8 5.05 5.00
160 INT130 Negative_regulation of OXTR 19 0.43 4.63 4.96 5.00
161 INT1285 Localization of Mmp13 12 0.78 8.98 4.93 5.00
162 INT15920 Regulation of Serpine1 34 0.42 17.36 4.89 5.00
163 INT99608 Transcription of MMP9 18 0.65 9.67 4.11 5.00
164 INT92653 Gene_expression of IL12B 21 0.75 17.28 3.89 5.00
165 INT44323 Positive_regulation of F8 32 0.60 24.88 3.89 5.00
166 INT10146 Negative_regulation of Vwf 27 0.40 17.11 3.69 5.00
167 INT158596 Binding of Tlr3 24 0.47 11.66 3.69 5.00
168 INT94431 Transcription of MMP1 14 0.56 4.1 3.66 5.00
169 INT173849 Positive_regulation of Localization of MMP3 7 0.49 4.6 3.65 5.00
170 INT32517 Positive_regulation of LRPAP1 13 0.49 7.4 3.44 5.00
171 INT14397 Gene_expression of Serpinc1 27 0.46 14.54 3.32 5.00
172 INT3881 Positive_regulation of Protein_catabolism of F13A1 21 0.41 20 3.28 5.00
173 INT157572 Gene_expression of Ccl12 10 0.70 10.52 3.09 5.00
174 INT61791 Positive_regulation of SH2B2 9 0.50 8.36 2.99 5.00
175 INT71933 Positive_regulation of Gene_expression of F2 19 0.56 14.24 2.53 5.00
176 INT151309 Positive_regulation of Positive_regulation of MMP3 5 0.60 2.62 2.5 5.00
177 INT120124 Transcription of MMP3 9 0.69 2.15 2.38 5.00
178 INT17598 Positive_regulation of CFHR1 11 0.50 2.6 2.38 5.00
179 INT64777 Negative_regulation of COL5A2 32 0.38 17.4 2.28 5.00
180 INT110184 Binding of HMI 9 0.28 5.52 2.24 5.00
181 INT16461 Negative_regulation of Gene_expression of PROC 13 0.24 4.39 2.17 5.00
182 INT3810 Regulation of CFHR1 7 0.38 1.19 2.13 5.00
183 INT17268 Localization of PLG 9 0.78 11.71 2.06 5.00
184 INT35146 Negative_regulation of PLG 27 0.57 17.63 1.98 5.00
185 INT64709 Gene_expression of VTN 11 0.67 11.01 1.97 5.00
186 INT108393 Positive_regulation of Localization of MMP1 5 0.40 0.85 1.91 5.00
187 INT128030 Gene_expression of GJA1 23 0.75 7.81 1.88 5.00
188 INT175298 Gene_expression of Meta 7 0.75 2.37 1.85 5.00
189 INT34864 Binding of Cp 23 0.47 5.17 1.78 5.00
190 INT67604 Gene_expression of SERPINC1 14 0.67 11.47 1.72 5.00
191 INT112648 Positive_regulation of Fn1 19 0.49 13.73 1.66 5.00
192 INT954 Positive_regulation of Gene_expression of GHRH 18 0.50 7.6 1.63 5.00
193 INT12062 Positive_regulation of Gene_expression of OXTR 9 0.69 1.04 1.63 5.00
194 INT91739 Positive_regulation of MYLK 9 0.54 2.89 1.58 5.00
195 INT175307 Regulation of Gene_expression of TLR2 9 0.56 7.08 1.58 5.00
196 INT174230 Positive_regulation of Gene_expression of IL12B 6 0.49 3.2 1.56 5.00
197 INT55479 Localization of Epo 13 0.81 6.1 1.53 5.00
198 INT175303 Positive_regulation of Pnlip 1 0.10 5.19 1.52 5.00
199 INT108273 Gene_expression of Phgdh 7 0.65 2.29 1.48 5.00
200 INT24685 Localization of Serpine1 12 0.59 7.76 1.32 5.00
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