D:Acanthamoeba Keratitis

Disease Term Synonyms Acanthamoeba Keratitides, Keratitides Acanthamoeba, Keratitis Acanthamoeba Documents 50 Hot Single Events 15 Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Acanthamoeba Keratitis. They are ordered first by their relevance to Acanthamoeba Keratitis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Overall Pain Relevance	Term Relevance
1	INT147112	LYZ Regulation of Binding of LTF	1	0.14	1.02	0.07	95.92

Single Events

The table below shows the top 200 pain related interactions that have been reported for Acanthamoeba Keratitis. They are ordered first by their pain relevance and then by number of times they were reported in Acanthamoeba Keratitis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Overall Pain Relevance	Term Relevance
1	INT81226	Gene_expression of Adk	9	0.64	9.28	4.81	100.00
2	INT291575	Negative_regulation of Gene_expression of Adk	1	0.32	1.05	0.03	100.00
3	INT291574	Protein_catabolism of Adk	1	0.49	0.99	0	100.00
4	INT3400	Positive_regulation of pr	57	0.68	36.9	16.24	99.16
5	INT147113	Binding of LTF	14	0.29	18.24	0.98	95.40
6	INT81629	Positive_regulation of Fas	58	0.70	59.63	12.94	93.92
7	INT93620	Positive_regulation of Gene_expression of Fasl	51	0.66	59.45	12.04	93.92
8	INT99942	Positive_regulation of Fasl	37	0.68	32.61	6.92	93.92
9	INT81628	Positive_regulation of Gene_expression of Fas	32	0.67	38.13	4.23	93.92
10	INT93626	Gene_expression of Fasl	118	0.75	115.24	25.11	92.80
11	INT81627	Gene_expression of Fas	120	0.78	115.51	15.36	92.80
12	INT120811	Gene_expression of Gopc	1174	0.59	428.49	150.55	90.96
13	INT88544	Gene_expression of MMRN1	102	0.75	68.8	14.55	90.40
14	INT17501	Negative_regulation of F2	70	0.58	32.23	7.51	83.52
15	INT192589	Negative_regulation of NEFM	1	0.00	1.13	0.03	83.04
16	INT166126	Gene_expression of MYD88	5	0.54	2.67	0.84	76.40
17	INT6483	Gene_expression of TNF	3152	0.78	2515.62	929.82	76.40
18	INT867	Gene_expression of IFNA1	930	0.78	594.85	168.03	76.40
19	INT117223	Gene_expression of TLR4	348	0.78	206.18	54.42	76.40
20	INT55170	Gene_expression of NFKB1	97	0.77	52.75	23.04	76.40
21	INT117222	Positive_regulation of Gene_expression of TLR4	80	0.70	51.6	12.9	76.40
22	INT71785	Gene_expression of MAPK3	22	0.75	11.35	8.21	76.40
23	INT94083	Gene_expression of NFASC	8	0.19	4.19	1.52	76.40
24	INT166125	Gene_expression of PHOSPHO1	4	0.75	3.06	0.24	76.40
25	INT107302	Negative_regulation of Gene_expression of Fasl	7	0.42	8.52	2.54	73.20
26	INT89967	Negative_regulation of Gene_expression of Fas	19	0.58	19.28	1.1	73.20
27	INT133766	Negative_regulation of Fasl	11	0.56	11.28	2.27	72.24
28	INT89966	Negative_regulation of Fas	26	0.58	24.83	3.5	71.52
29	INT187050	Localization of RENBP	8	0.35	6.92	0.61	61.52
30	INT90091	Gene_expression of GOPC	967	0.67	366.22	103.6	60.68
31	INT77652	Negative_regulation of Gene_expression of IL8	99	0.59	67.57	30.21	51.04
32	INT10832	Gene_expression of IL8	1050	0.78	698.72	270	50.48
33	INT166127	Negative_regulation of Gene_expression of IFNB1	1	0.25	1.06	0.21	48.60
34	INT145001	Gene_expression of IFNB1	6	0.68	4.36	1.77	48.04
35	INT78694	Positive_regulation of Gene_expression of Casp3	46	0.66	18.64	19.62	32.40
36	INT31116	Gene_expression of Casp3	192	0.78	78.21	57.43	31.28
37	INT4498	Gene_expression of F2	83	0.65	57.4	10.8	30.60
38	INT22159	Gene_expression of AMT	11	0.75	2.19	1.5	20.28
39	INT65600	Positive_regulation of Casp3	376	0.70	198.44	128.03	5.00
40	INT27096	Positive_regulation of Nfkb1	325	0.70	195.11	109.06	5.00
41	INT11318	Gene_expression of Gtf3a	274	0.52	183.82	60.89	5.00
42	INT25383	Gene_expression of Csf2	222	0.76	152.93	43.32	5.00
43	INT77307	Gene_expression of Bcl2	399	0.77	319.77	38	5.00
44	INT59466	Gene_expression of ISYNA1	204	0.77	112.57	35.48	5.00
45	INT9694	Positive_regulation of Csf2	102	0.68	70.09	33.07	5.00
46	INT73982	Gene_expression of Hmox1	141	0.78	119.43	32.17	5.00
47	INT35406	Localization of Tnf	94	0.81	64.63	31.65	5.00
48	INT93738	Gene_expression of Tnfrsf1a	63	0.74	57.66	23.09	5.00
49	INT171666	Regulation of GOPC	117	0.39	40.41	15.47	5.00
50	INT1888	Protein_catabolism of F13A1	97	0.99	63.48	14.82	5.00
51	INT72127	Protein_catabolism of MMRN1	68	0.52	56	14.13	5.00
52	INT2129	Positive_regulation of F2	83	0.70	58.95	12.63	5.00
53	INT27268	Localization of Gtf3a	71	0.21	56.93	12.51	5.00
54	INT81640	Positive_regulation of Gene_expression of Bcl2	106	0.69	84.58	11.63	5.00
55	INT25381	Localization of Csf2	62	0.76	47.48	9.03	5.00
56	INT25392	Positive_regulation of Gene_expression of Csf2	41	0.49	34.28	8.36	5.00
57	INT77306	Negative_regulation of Gene_expression of Bcl2	46	0.58	38.05	7.71	5.00
58	INT112986	Positive_regulation of S100b	19	0.70	17.61	6.86	5.00
59	INT86805	Localization of HGF	49	0.71	28.48	6.35	5.00
60	INT4561	Gene_expression of PLG	32	0.75	17.59	6.21	5.00
61	INT8106	Gene_expression of GGT1	31	0.75	18.65	6.1	5.00
62	INT88545	Localization of MMRN1	21	0.78	16.67	4.01	5.00
63	INT64234	Regulation of Bcl2	41	0.54	31.88	3.16	5.00
64	INT180971	Protein_catabolism of GOPC	21	0.77	6.15	2.98	5.00
65	INT98554	Positive_regulation of Casp8	20	0.67	21.32	2.9	5.00
66	INT195085	Gene_expression of S100b	12	0.56	12.26	2.33	5.00
67	INT4560	Protein_catabolism of PLG	18	0.96	11.64	2.32	5.00
68	INT97152	Protein_catabolism of COL1A1	11	0.74	8.03	2.3	5.00
69	INT31118	Localization of Casp3	17	0.73	11.55	2.3	5.00
70	INT116194	Gene_expression of Casp8	14	0.75	14.61	2.13	5.00
71	INT175655	Regulation of MMRN1	16	0.12	9.96	2.12	5.00
72	INT25286	Localization of IL1RL1	7	0.56	3.17	2.07	5.00
73	INT121784	Regulation of Gene_expression of Fas	7	0.38	5.68	1.86	5.00
74	INT22871	Gene_expression of ELN	30	0.68	14.86	1.33	5.00
75	INT115948	Regulation of Gene_expression of MMRN1	7	0.26	10.37	1.33	5.00
76	INT190190	Protein_catabolism of ELN	5	0.22	2.81	1.27	5.00
77	INT81043	Negative_regulation of Kctd1	9	0.57	7.68	1.06	5.00
78	INT31117	Binding of Casp3	14	0.23	5.27	0.93	5.00
79	INT139180	Regulation of Positive_regulation of Fas	2	0.43	2.19	0.69	5.00
80	INT100822	Localization of Fas	8	0.74	6.13	0.48	5.00
81	INT192587	Negative_regulation of Protein_catabolism of GOPC	4	0.22	1.15	0.41	5.00
82	INT192590	Gene_expression of CA4	3	0.75	1.57	0.41	5.00
83	INT142872	Regulation of Casp8	6	0.29	3.11	0.39	5.00
84	INT265607	Gene_expression of TAF8	11	0.32	9.91	0.35	5.00
85	INT22873	Positive_regulation of ELN	6	0.45	3.74	0.33	5.00
86	INT201453	Protein_catabolism of Hmox1	3	0.95	4.25	0.23	5.00
87	INT88128	Positive_regulation of Localization of HGF	7	0.45	2.74	0.17	5.00
88	INT347940	Regulation of Positive_regulation of Fasl	1	0.30	1.95	0.13	5.00
89	INT227406	Regulation of Bcl2l10	2	0.03	2.99	0.13	5.00
90	INT192591	Protein_catabolism of RENBP	1	0.02	0.94	0.12	5.00
91	INT256923	Regulation of Gene_expression of Casp8	2	0.11	2.31	0.04	5.00
92	INT190027	Regulation of Apaf1	2	0.16	2.59	0.04	5.00
93	INT192593	Protein_catabolism of ECM1	1	0.03	0.63	0.04	5.00
94	INT321555	Negative_regulation of Vcl	3	0.12	2.41	0.03	5.00
95	INT154990	Negative_regulation of TJP1	2	0.20	1.74	0.03	5.00
96	INT255408	Protein_catabolism of Pymr	2	0.06	1.71	0	5.00
97	INT192594	Positive_regulation of Protein_catabolism of ELN	1	0.08	0.3	0	5.00