D:Acanthosis

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pChart

Disease Term
Synonyms Acanthosis Nigricans, Keratosis Nigricans
Documents 102
Hot Single Events 74
Hot Interactions 6

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Acanthosis. They are ordered first by their relevance to Acanthosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT334527 Sema3a Negative_regulation of Gene_expression of Il4 1 0.15 0.48 0.14 98.32
2 INT334531 Nrp1 Negative_regulation of Gene_expression of Il4 1 0.08 0.48 0.14 97.88
3 INT334534 Nrp1 Negative_regulation of Gene_expression of Sema3a 1 0.17 0.48 0.14 97.88
4 INT334528 Nrp1 Negative_regulation of Sema3a 1 0.17 0.47 0.13 97.88
5 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24 83.36
6 INT285561 Il23a Positive_regulation of Gene_expression of Il22 2 0.06 2.45 0.93 83.20
7 INT182778 IGF1 Positive_regulation of Gene_expression of ETV3 1 0.03 1.89 0 69.76
8 INT182783 INS Positive_regulation of Gene_expression of ETV3 1 0.01 1.89 0 69.76
9 INT182777 IAPP Positive_regulation of Gene_expression of ETV3 1 0.06 1.88 0 69.76
10 INT334522 Ngf Positive_regulation of Nrp1 1 0.19 0.93 0.22 69.28
11 INT334525 Ngf Positive_regulation of Gene_expression of Nrp1 1 0.19 0.93 0.22 69.28
12 INT182804 Binding of ETV3 and T2DM 1 0.10 2.62 0 68.92
13 INT350120 FSHR Regulation of CYP19A1 1 0.01 3.02 0 68.00
14 INT182784 IGF1 Positive_regulation of Gene_expression of INS 1 0.02 1.87 0 68.00
15 INT182776 IAPP Positive_regulation of Gene_expression of INS 1 0.03 1.87 0 68.00
16 INT329801 Binding of CAMP and IFNA1 1 0.03 1.48 0.4 62.88
17 INT350116 FSHR Positive_regulation of Gene_expression of CGA 1 0.01 1.28 0 61.64
18 INT284891 FSHR Positive_regulation of Gene_expression of PLOD1 2 0.03 1.32 0.11 60.80
19 INT350117 GNRHR Negative_regulation of Localization of FSHR 1 0.01 1.06 0 57.08
20 INT350113 GNRHR Negative_regulation of Localization of PLOD1 1 0.01 1.06 0 57.08
21 INT350115 GNRH1 Negative_regulation of Localization of PLOD1 1 0.04 0.99 0 55.80
22 INT350122 GNRH1 Negative_regulation of Localization of FSHR 1 0.05 0.99 0 55.80
23 INT350119 Positive_regulation of GNRH1 Positive_regulation of PLOD1 1 0.04 0.86 0.03 52.92
24 INT350114 Positive_regulation of GNRH1 Positive_regulation of FSHR 1 0.05 0.86 0.03 52.92
25 INT45780 GNRH1 Positive_regulation of PLOD1 3 0.07 1.02 0.63 52.52
26 INT54584 GNRH1 Positive_regulation of FSHR 3 0.48 2.02 0.54 52.08
27 INT334918 GNRH1 Positive_regulation of Gene_expression of FSHR 2 0.11 1.27 0.03 52.08
28 INT306732 Il17a Positive_regulation of Gene_expression of Il2 1 0.09 1.07 0.46 41.24
29 INT306731 Il22 Positive_regulation of Gene_expression of Il2 1 0.12 1.07 0.46 40.84
30 INT334532 Sema3a Negative_regulation of Gene_expression of Nrp1 1 0.19 7.58 2 28.56
31 INT334537 Sema3a Negative_regulation of Gene_expression of Plxna1 1 0.08 3.76 1 26.64
32 INT267973 Binding of CHKB and ESR1 1 0.02 1.67 0.13 13.48
33 INT334526 Trpv1 Positive_regulation of Gene_expression of Sema3a 1 0.31 0.92 0.55 7.60
34 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85 5.00
35 INT306745 Binding of Il12a and IL23A 1 0.10 3.25 1.56 5.00
36 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46 5.00
37 INT334529 Pax3 Positive_regulation of Gene_expression of Ngf 1 0.03 0.31 0.91 5.00
38 INT90387 ROS1 Positive_regulation of NFKB1 4 0.32 2.35 0.87 5.00
39 INT285562 Binding of Il27ra and Il27 1 0.10 2.19 0.67 5.00
40 INT285467 Negative_regulation of Binding of IL1B and IL1RN 1 0.05 1.33 0.61 5.00
41 INT329794 TLR2 Positive_regulation of Positive_regulation of IL12A 1 0.01 1.05 0.44 5.00
42 INT329803 TLR2 Positive_regulation of Positive_regulation of IL6 1 0.01 0.94 0.41 5.00
43 INT329800 TLR2 Positive_regulation of Positive_regulation of IL8 1 0.01 0.99 0.41 5.00
44 INT285560 Il23a Positive_regulation of Il17a 1 0.09 1.45 0.39 5.00
45 INT329799 Binding of CD14 and LY96 2 0.04 1.02 0.39 5.00
46 INT285571 Binding of IL8 and Il17a 1 0.04 1.03 0.38 5.00
47 INT334533 Binding of Foxq1 and Ngf 1 0.05 0.8 0.38 5.00
48 INT285568 Binding of TNF and Tnfsf10 1 0.12 1.39 0.36 5.00
49 INT285557 Eae2 Positive_regulation of Cia1 1 0.02 1.85 0.36 5.00
50 INT285465 IL7 Positive_regulation of TNF 1 0.04 0.67 0.35 5.00
51 INT285570 Binding of IL8 and Cdkn1c 1 0.11 0.76 0.34 5.00
52 INT285565 Positive_regulation of Zeb1 Negative_regulation of IL2 1 0.02 0.62 0.33 5.00
53 INT285558 Binding of Il11ra1 and Il27 1 0.05 1.1 0.33 5.00
54 INT285566 F8 Negative_regulation of IL2 1 0.00 0.62 0.33 5.00
55 INT285563 Zeb1 Negative_regulation of IL2 1 0.01 0.62 0.33 5.00
56 INT285567 Binding of IL1B and Cdc42 1 0.03 0.77 0.31 5.00
57 INT285564 Binding of IL1B and Ripk2 1 0.04 0.76 0.31 5.00
58 INT182771 ROS1 Positive_regulation of NFKB1 Positive_regulation of CRP 1 0.00 3.83 0.28 5.00
59 INT306714 IL23A Positive_regulation of TNF 1 0.29 0.5 0.21 5.00
60 INT182606 Binding of MSH2 and MSH3 1 0.12 1.4 0.21 5.00
61 INT306746 Il12a Positive_regulation of TNF 1 0.24 0.5 0.21 5.00
62 INT306744 IL23A Positive_regulation of Il12a 1 0.13 0.59 0.2 5.00
63 INT329795 IL6 Positive_regulation of Transcription of CCL5 1 0.02 0.59 0.17 5.00
64 INT306747 IL23A Positive_regulation of Il17a 1 0.05 0.51 0.16 5.00
65 INT329796 TICAM1 Positive_regulation of IFNA1 2 0.02 0.89 0.15 5.00
66 INT182772 ROS1 Positive_regulation of NFKB1 Positive_regulation of IL1B 1 0.00 1.89 0.14 5.00
67 INT182773 ROS1 Positive_regulation of NFKB1 Positive_regulation of IL6 1 0.00 1.9 0.14 5.00
68 INT182780 NFKB1 Positive_regulation of IL1B 1 0.00 1.8 0.14 5.00
69 INT182782 NFKB1 Positive_regulation of IL6 1 0.00 1.8 0.14 5.00
70 INT334530 Sema3a Regulation of Il18 1 0.18 1.61 0.13 5.00
71 INT334524 Sema3a Regulation of Foxq1 1 0.04 1.61 0.13 5.00
72 INT329797 Positive_regulation of TLR2 Positive_regulation of Gene_expression of IL6 1 0.02 1.67 0.11 5.00
73 INT182607 Binding of MLH1 and MSH3 1 0.04 0.81 0.11 5.00
74 INT329802 Positive_regulation of TLR2 Regulation of Gene_expression of IL6 1 0.01 1.67 0.11 5.00
75 INT329798 Binding of MYD88 and TICAM1 2 0.01 0.24 0.1 5.00
76 INT251469 INS Negative_regulation of Gene_expression of SHBG 2 0.11 4.11 0.08 5.00
77 INT303561 Binding of Fgf7 and Fgfr2 1 0.42 0.88 0.07 5.00
78 INT303560 Binding of Fgfr2 and Fgf22 1 0.41 0.89 0.07 5.00
79 INT303562 Binding of Fgf10 and Fgfr2 1 0.40 0.88 0.07 5.00
80 INT182775 Binding of PTH and ROS1 1 0.04 1.73 0.04 5.00
81 INT350121 INS Negative_regulation of Positive_regulation of SHBG 1 0.09 1.48 0.04 5.00
82 INT290877 Binding of Bcl2a1c and Lepr 1 0.00 0.87 0.04 5.00
83 INT350118 INS Negative_regulation of SHBG 1 0.09 1.42 0.04 5.00
84 INT303557 Binding of Dysf and Fgf22 1 0.01 0.45 0.03 5.00
85 INT303558 Binding of Fgfr2 and Dysf 1 0.01 0.44 0.03 5.00
86 INT303563 Binding of Fgf10 and Dysf 1 0.00 0.44 0.03 5.00
87 INT303559 Binding of Fgf7 and Dysf 1 0.01 0.44 0.03 5.00
88 INT342281 Binding of INS and Esr1 1 0.08 0.57 0 5.00
89 INT334538 Il18 Positive_regulation of Localization of IFN1@ 1 0.34 0.65 0 5.00
90 INT227399 Binding of D5Mit424 and Alms1 1 0.01 0.71 0 5.00
91 INT267974 APOB Negative_regulation of HSD11B1 1 0.01 0.75 0 5.00
92 INT290861 MNT Positive_regulation of INS 1 0.03 1.78 0 5.00
93 INT182774 Binding of ETV3 and SAE1 1 0.00 1.17 0 5.00
94 INT227398 Binding of H2afy and Alms1 1 0.01 1.42 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Acanthosis. They are ordered first by their pain relevance and then by number of times they were reported in Acanthosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT135411 Gene_expression of Il23a 76 0.72 72.87 26.15 100.00
2 INT296054 Positive_regulation of Il22 13 0.33 17.97 4.06 99.80
3 INT4360 Gene_expression of Hypism 29 0.22 38.1 4.07 99.68
4 INT73675 Gene_expression of Il1f6 2 0.09 3.3 0.37 99.50
5 INT303549 Positive_regulation of Gene_expression of Il1f6 1 0.08 0.96 0.22 99.50
6 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75 99.40
7 INT35998 Positive_regulation of Gene_expression of Calca 31 0.70 16.16 16.98 99.40
8 INT300718 Negative_regulation of Ptrf 1 0.34 4.1 0.18 99.34
9 INT285496 Regulation of Negative_regulation of Il22 1 0.10 1.13 0.37 99.16
10 INT285482 Negative_regulation of Il22 3 0.30 3.02 1.37 99.16
11 INT160564 Gene_expression of Il22 64 0.55 59.29 20.9 98.72
12 INT55886 Negative_regulation of Gene_expression of Il4 47 0.57 26.04 11.42 98.56
13 INT1335 Negative_regulation of Oprl1 123 0.59 18.02 77.13 98.44
14 INT153189 Gene_expression of Sema3a 19 0.75 14.37 4.21 98.32
15 INT240113 Gene_expression of Nrp1 11 0.30 10.88 2.24 97.88
16 INT101203 Negative_regulation of Gene_expression of Calca 12 0.59 7.06 10.72 97.48
17 INT8747 Positive_regulation of Ins1 221 0.69 154.28 35.15 97.44
18 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 97.40
19 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 97.24
20 INT164683 Negative_regulation of Gene_expression of PKP1 1 0.59 1.5 0.17 97.08
21 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 97.02
22 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 97.02
23 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 96.84
24 INT164682 Gene_expression of PKP1 3 0.78 3.04 0.17 96.76
25 INT303544 Positive_regulation of Negative_regulation of Fgfr1 1 0.47 1.07 0.03 96.40
26 INT303547 Positive_regulation of Negative_regulation of Fgfr2 1 0.48 1.07 0.03 96.40
27 INT196155 Binding of Nrp1 5 0.16 2.38 0.69 95.72
28 INT221545 Binding of Sema3a 2 0.33 1.4 0.53 95.72
29 INT94454 Gene_expression of CD68 73 0.72 63.94 10.43 95.40
30 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 95.40
31 INT6810 Gene_expression of ENO2 70 0.78 54.8 8.35 95.40
32 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17 95.16
33 INT74520 Positive_regulation of CD68 30 0.61 31.68 7.59 95.16
34 INT15652 Positive_regulation of ENO2 37 0.68 33.39 5.02 95.16
35 INT157121 Gene_expression of GAD2 15 0.67 7.21 5.91 94.72
36 INT22834 Negative_regulation of CYP21A2 28 0.58 23.07 7.13 94.64
37 INT202626 Negative_regulation of Fgfr2 2 0.41 2.48 0.42 94.48
38 INT157122 Gene_expression of PTPRN 1 0.65 2.15 0.17 94.28
39 INT173508 Negative_regulation of Fgfr1 4 0.55 5.08 0.66 93.68
40 INT285489 Positive_regulation of Gene_expression of Il22 9 0.32 10.97 3.63 93.16
41 INT97597 Positive_regulation of Gene_expression of Il20 2 0.21 1.4 0.86 93.16
42 INT285487 Positive_regulation of Gene_expression of Il19 1 0.08 1.2 0.41 93.16
43 INT285495 Positive_regulation of Gene_expression of Il24 1 0.10 1.2 0.41 93.16
44 INT225250 Gene_expression of Il24 3 0.16 2.04 0.47 93.16
45 INT97599 Gene_expression of Il20 4 0.23 5.11 2.98 93.16
46 INT174792 Gene_expression of Il19 2 0.12 1.97 0.67 93.16
47 INT176649 Negative_regulation of Localization of Cd4 5 0.32 2.41 0.51 92.64
48 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 92.04
49 INT160562 Localization of Cd4 49 0.71 27.58 6.78 92.04
50 INT176080 Gene_expression of Fgfr2 4 0.68 2.34 0.24 91.68
51 INT150023 Positive_regulation of Il23a 25 0.38 18.33 6.32 90.12
52 INT39244 Gene_expression of TMPO 137 0.77 14.55 11.83 89.52
53 INT310442 Gene_expression of POLA1 1 0.30 0.97 0 89.52
54 INT45899 Regulation of Localization of LGR6 3 0.27 1.85 0.64 89.44
55 INT45901 Localization of LGR6 5 0.80 2.48 1.64 88.88
56 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 88.80
57 INT303543 Gene_expression of Il1f8 1 0.42 3.28 1.43 88.36
58 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 88.36
59 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 87.68
60 INT182800 Positive_regulation of ETV3 5 0.46 10.01 0.14 87.36
61 INT182754 Positive_regulation of T2DM 1 0.67 4.5 0.03 87.36
62 INT214 Localization of AVP 370 0.81 208.51 91.09 87.28
63 INT181879 Negative_regulation of Apoa1 8 0.55 8.18 1.11 87.12
64 INT6852 Localization of TNF 883 0.81 705.95 270.84 86.80
65 INT117120 Gene_expression of Krt14 20 0.75 6.53 0.77 86.72
66 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 86.20
67 INT158409 Gene_expression of T2DM 3 0.65 9.58 0.56 85.56
68 INT121834 Gene_expression of IAPP 24 0.66 20.96 0.26 85.36
69 INT100096 Regulation of Slc6a4 24 0.62 7.25 12.28 85.28
70 INT103446 Gene_expression of Krt10 4 0.39 2.21 0.29 84.68
71 INT299511 Negative_regulation of Elpt 2 0.07 1.79 0.4 84.24
72 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6 84.04
73 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 81.80
74 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64 80.36
75 INT546 Binding of ALB 311 0.48 85.98 60.14 79.72
76 INT159113 Binding of MT1F 5 0.42 1.85 0.23 79.72
77 INT273628 Gene_expression of Lor 3 0.52 3.07 0.38 78.68
78 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 77.92
79 INT303529 Positive_regulation of Gene_expression of Il1f8 1 0.27 0.89 0.25 77.04
80 INT175312 Positive_regulation of Gene_expression of IL23A 17 0.45 14.8 5.05 76.68
81 INT161515 Positive_regulation of Gene_expression of Il17a 50 0.64 41.52 13.82 76.68
82 INT226463 Positive_regulation of IL23A 23 0.45 21.58 9.18 76.68
83 INT306735 Positive_regulation of Positive_regulation of IL23A 4 0.26 3.25 1.04 76.68
84 INT306727 Positive_regulation of Positive_regulation of Il22 1 0.12 1.26 0.3 76.68
85 INT168263 Gene_expression of IL23A 57 0.58 47.1 17.67 76.08
86 INT3040 Gene_expression of MIA3 81 0.24 53.61 12.62 75.32
87 INT177832 Positive_regulation of Gene_expression of MT1F 5 0.28 2.75 1.05 74.20
88 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93 74.08
89 INT108761 Localization of Alms1 24 0.70 13.92 3.74 74.08
90 INT158542 Gene_expression of HTN1 10 0.75 10.69 1.07 73.84
91 INT158541 Positive_regulation of Gene_expression of HTN1 3 0.40 5.88 0.97 73.84
92 INT20006 Gene_expression of MT1F 27 0.68 19.55 3.18 73.72
93 INT133172 Gene_expression of Il12b 98 0.75 52.16 10.68 72.96
94 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09 72.20
95 INT35450 Negative_regulation of Htr2a 7 0.47 3.46 3.33 72.20
96 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 72.00
97 INT150949 Gene_expression of Fgfr1 6 0.63 5.71 0.57 71.92
98 INT181046 Gene_expression of Krt6a 3 0.37 2.03 0.03 71.80
99 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 71.20
100 INT12054 Negative_regulation of MIA3 32 0.45 23.2 6.18 70.92
101 INT294726 Positive_regulation of Lts1 5 0.49 4.06 0.87 70.80
102 INT185246 Gene_expression of Psmd1 26 0.50 8.89 3.73 70.20
103 INT182788 Gene_expression of ETV3 8 0.40 11.33 0.36 69.76
104 INT182787 Binding of ETV3 14 0.37 25.44 0.37 68.92
105 INT131019 Binding of T2DM 6 0.47 6.97 0.31 68.92
106 INT300717 Gene_expression of Ptrf 1 0.61 3.64 0.18 68.92
107 INT92354 Localization of ESR1 77 0.75 33.04 15.51 68.84
108 INT3536 Positive_regulation of Nrp1 2 0.19 0.93 0.7 68.64
109 INT260823 Positive_regulation of Gene_expression of Nrp1 3 0.19 2.14 0.65 68.64
110 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 68.36
111 INT172458 Regulation of Gopc 155 0.53 62.57 24.86 68.16
112 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 67.12
113 INT310439 Regulation of POLA1 1 0.24 2.21 0 66.96
114 INT306726 Localization of Il22 4 0.57 5.52 2.57 65.96
115 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17 65.92
116 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 65.92
117 INT133030 Positive_regulation of Gene_expression of TLR2 53 0.65 38.15 10.65 65.92
118 INT12618 Positive_regulation of IAPP 54 0.68 32.03 2.29 65.92
119 INT79413 Gene_expression of CAMP 13 0.75 8.3 4.02 63.44
120 INT79412 Positive_regulation of Gene_expression of CAMP 5 0.49 3.73 1.55 63.44
121 INT48066 Binding of CAMP 3 0.36 2.69 0.93 62.88
122 INT157227 Localization of Tst 9 0.74 6.78 0.58 62.88
123 INT285474 Negative_regulation of Gene_expression of Fgfr1 2 0.40 2.15 0.24 62.44
124 INT129762 Binding of HTN1 5 0.03 5.68 0.19 62.20
125 INT2982 Positive_regulation of Gene_expression of CGA 17 0.59 9.08 1.99 62.04
126 INT7972 Positive_regulation of Gene_expression of PLOD1 15 0.42 5.73 1.96 62.04
127 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 62.00
128 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 61.64
129 INT300712 Negative_regulation of Gene_expression of Elpt 1 0.07 1.02 0.09 61.36
130 INT300716 Gene_expression of Elpt 1 0.11 1.02 0.09 61.36
131 INT18844 Binding of IAPP 11 0.36 11.01 1.45 61.20
132 INT181049 Positive_regulation of Gene_expression of Krt6a 2 0.22 1.03 0 61.00
133 INT7970 Gene_expression of PLOD1 120 0.71 44.42 15.54 60.80
134 INT16130 Binding of IGF1 67 0.48 27.43 2.95 60.16
135 INT204529 Positive_regulation of TLR9 18 0.62 15.62 3.99 59.84
136 INT86023 Transcription of PPARA 60 0.66 25.8 5.7 58.92
137 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 58.44
138 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 55.80
139 INT920 Localization of PLOD1 223 0.81 42.25 78.7 55.16
140 INT912 Localization of FSHR 91 0.79 23.61 15.58 55.04
141 INT152729 Negative_regulation of Gene_expression of S100a8 33 0.42 32.25 13.64 54.68
142 INT303531 Negative_regulation of Gene_expression of Il1f8 1 0.23 0.75 0.32 54.68
143 INT42244 Regulation of Gene_expression of PTH 5 0.45 3.95 0.34 54.48
144 INT132246 Negative_regulation of S100a8 19 0.43 22 7.25 54.24
145 INT303534 Negative_regulation of Il1f8 1 0.23 0.59 0.28 54.24
146 INT9660 Regulation of TNF 363 0.62 312.94 139.99 53.68
147 INT285470 Regulation of Il22 4 0.11 4.18 1.21 53.68
148 INT5131 Gene_expression of GNRH1 109 0.78 28.79 23.94 53.56
149 INT15609 Positive_regulation of Gene_expression of GNRH1 17 0.49 5.15 3.34 53.56
150 INT55002 Gene_expression of ASAP1 46 0.64 22.8 3.2 53.20
151 INT153190 Negative_regulation of Sema3a 7 0.56 7.94 1.76 53.20
152 INT158486 Negative_regulation of Gene_expression of Sema3a 4 0.41 2.49 0.57 53.20
153 INT6512 Gene_expression of PTH 103 0.77 76.29 6.33 51.88
154 INT4145 Gene_expression of FSHR 124 0.77 44.98 13.04 51.48
155 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 51.44
156 INT303532 Positive_regulation of 2400001E08Rik 1 0.15 0.94 0.23 51.12
157 INT3933 Positive_regulation of PLOD1 128 0.70 30.76 42.03 50.04
158 INT26538 Positive_regulation of FSHR 103 0.69 30.95 15.33 50.04
159 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 49.36
160 INT246031 Gene_expression of IL22 10 0.40 9.48 5.11 49.36
161 INT78210 Gene_expression of MCC 7 0.65 1.8 0.98 47.68
162 INT19211 Binding of Shbg 35 0.48 16.29 3.31 47.20
163 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 44.64
164 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41 44.64
165 INT129207 Gene_expression of Cxcl1 114 0.75 68.54 30.82 44.64
166 INT172173 Protein_catabolism of TNF 16 0.96 9.95 3.79 43.92
167 INT220506 Binding of Cav1 13 0.45 5.46 0.38 43.32
168 INT237337 Binding of Cav3 3 0.44 2.63 0.11 43.32
169 INT285494 Positive_regulation of Gene_expression of Fgf7 2 0.40 1.48 0.13 42.88
170 INT260760 Positive_regulation of Fgf10 2 0.53 0.43 0.03 42.88
171 INT178396 Positive_regulation of Fgf7 2 0.55 0.98 0.03 42.88
172 INT303535 Positive_regulation of Gene_expression of Fgf10 1 0.53 0.34 0.03 42.88
173 INT310443 Negative_regulation of POLA1 1 0.16 0.31 0 42.12
174 INT296583 Gene_expression of Fgf10 3 0.59 2.64 0.57 42.08
175 INT181032 Gene_expression of Fgf7 8 0.61 5.96 1.41 41.28
176 INT235510 Binding of Il17a 14 0.34 10.67 3.99 41.24
177 INT306723 Binding of Il22 3 0.11 2.44 0.97 40.84
178 INT11807 Gene_expression of Il2 266 0.78 112 64.97 39.52
179 INT11804 Positive_regulation of Gene_expression of Il2 70 0.70 33 21.63 39.52
180 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 35.72
181 INT75540 Positive_regulation of TH1L 62 0.67 43.45 15.02 35.68
182 INT39243 Regulation of TMPO 20 0.61 5.66 2.67 33.52
183 INT221531 Gene_expression of Plxna1 7 0.75 4.51 1.31 31.60
184 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 31.56
185 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 28.80
186 INT306739 Positive_regulation of Gene_expression of IL22 2 0.28 2.2 1.36 25.88
187 INT164684 Transcription of PKP1 1 0.69 0.75 0.13 25.00
188 INT164680 Negative_regulation of PKP1 1 0.43 0.38 0.07 25.00
189 INT164681 Transcription of PKP2 1 0.57 0.38 0.07 25.00
190 INT164685 Negative_regulation of PKP2 1 0.35 0.38 0.07 25.00
191 INT107992 Gene_expression of MSH2 39 0.78 37.09 1.6 24.32
192 INT285468 Transcription of Ets2 1 0.06 0.67 0.55 24.24
193 INT285483 Positive_regulation of Transcription of Ets2 1 0.05 0.67 0.55 24.24
194 INT303524 Positive_regulation of Fgfr2 1 0.66 0.22 0 24.16
195 INT211637 Positive_regulation of Ets2 2 0.31 0.94 0.54 23.68
196 INT8340 Negative_regulation of SHBG 49 0.57 35.96 4.73 23.12
197 INT303538 Positive_regulation of Fgfr1 3 0.65 0.92 0.03 23.04
198 INT94784 Binding of ROS1 113 0.40 71.57 10.26 23.00
199 INT297421 Positive_regulation of Flg 1 0.40 1.6 0.53 20.00
200 INT80420 Gene_expression of IFI27 145 0.78 63.61 8.83 19.16
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