D:Achondroplasia

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Disease Term
Synonyms Achondroplasia Disorder, Achondroplasia Syndrome, Achondroplasias, ACHONDROPLASTIC DWARF, Achondroplastic Dwarfism, CHONDRODYSTROPHIA, CHONDRODYSTROPHIA FETALIS, CHONDRODYSTROPHIA FOETALIS, Chondrodystrophy Syndrome, Congenital Osteosclerosis
Documents 66
Hot Single Events 9
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Achondroplasia. They are ordered first by their relevance to Achondroplasia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT189021 NOX5 Positive_regulation of ROS1 1 0.26 0.2 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Achondroplasia. They are ordered first by their pain relevance and then by number of times they were reported in Achondroplasia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 97.68
2 INT197143 Positive_regulation of Renbp 15 0.33 9.41 1.31 96.76
3 INT677 Positive_regulation of CST3 20 0.67 17.47 6 89.28
4 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 88.92
5 INT156827 Localization of MRI1 25 0.65 16.06 8.33 88.56
6 INT243058 Positive_regulation of Positive_regulation of Fgfr3 1 0.46 0.8 0 87.24
7 INT243057 Positive_regulation of Fgfr3 1 0.46 0.79 0 86.84
8 INT94784 Binding of ROS1 113 0.40 71.57 10.26 80.68
9 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 80.68
10 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 79.20
11 INT174106 Binding of Renbp 18 0.24 15.82 0.58 79.12
12 INT205617 Negative_regulation of Positive_regulation of Renbp 1 0.16 1.04 0.21 59.64
13 INT161807 Phosphorylation of ROS1 10 0.43 4.86 0.62 52.96
14 INT205619 Regulation of Renbp 6 0.17 1.91 0.55 51.92
15 INT189030 Phosphorylation of PTPN3 3 0.31 1.17 0.39 51.84
16 INT189032 Positive_regulation of Phosphorylation of PTPN3 1 0.06 0.36 0 51.84
17 INT189039 Negative_regulation of PTPN3 3 0.21 1.01 0.16 48.44
18 INT66383 Phosphorylation of Prkaca 143 0.80 30.85 43.38 39.32
19 INT205618 Gene_expression of Renbp 15 0.26 9.26 1.04 33.28
20 INT69436 Negative_regulation of Gene_expression of ROS1 81 0.38 46.58 12.22 24.36
21 INT148564 Localization of HAL 8 0.68 2.46 0.62 6.56
22 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 5.00
23 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
24 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 5.00
25 INT326 Gene_expression of Gnrhr 105 0.76 35.87 34.93 5.00
26 INT69435 Negative_regulation of ROS1 74 0.51 50.38 13.71 5.00
27 INT112003 Localization of ROS1 94 0.73 66.32 12.16 5.00
28 INT116433 Gene_expression of CYBB 93 0.70 50.44 11.91 5.00
29 INT110178 Phosphorylation of MAPK14 40 0.68 19.38 10.37 5.00
30 INT16131 Negative_regulation of GBE1 37 0.30 10.32 8.15 5.00
31 INT1755 Gene_expression of GBE1 28 0.26 8.32 5.18 5.00
32 INT35765 Gene_expression of TXNRD1 47 0.56 9.16 4.43 5.00
33 INT108710 Gene_expression of HAL 36 0.58 14.75 2.16 5.00
34 INT59790 Binding of BCR 16 0.36 15.34 1.75 5.00
35 INT30039 Negative_regulation of HAL 7 0.42 4.32 1.61 5.00
36 INT108913 Positive_regulation of HAL 10 0.28 5.71 1.59 5.00
37 INT182297 Positive_regulation of Phosphorylation of MAPK14 7 0.42 3.36 1.53 5.00
38 INT113785 Negative_regulation of Eef1a2 15 0.31 1.33 1.48 5.00
39 INT50010 Negative_regulation of CHR 5 0.42 3.64 1.41 5.00
40 INT11203 Gene_expression of BCR 30 0.75 33.49 1.22 5.00
41 INT30041 Binding of HAL 8 0.35 2.36 0.95 5.00
42 INT189038 Regulation of Protein_catabolism of IL9 2 0.09 0.07 0.24 5.00
43 INT189037 Protein_catabolism of IL9 2 0.18 0.07 0.21 5.00
44 INT189034 Gene_expression of NOX5 5 0.48 1.99 0.1 5.00
45 INT180620 Positive_regulation of Positive_regulation of HAL 1 0.06 0.09 0 5.00
46 INT180621 Negative_regulation of Gene_expression of HAL 1 0.05 0 0 5.00
47 INT189029 Protein_catabolism of PRRX1 1 0.86 0.07 0 5.00
48 INT189036 Regulation of Protein_catabolism of PRRX1 1 0.44 0.07 0 5.00
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