D:Acro-osteolysis

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pChart

Disease Term
Synonyms ACRO OSTEOLYSIS, Acro Osteolysis Syndrome, Acro Osteolysis Syndromes, Acroosteolysis, Acroosteolysis Syndrome
Documents 13
Hot Single Events 3
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Acro-osteolysis. They are ordered first by their relevance to Acro-osteolysis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT181998 TNFRSF11B Negative_regulation of Gene_expression of CTSK 1 0.07 1.98 0.27 90.48
2 INT181996 TNFRSF11B Positive_regulation of Gene_expression of TIMP1 1 0.00 0.67 0.18 5.00
3 INT181997 TNFRSF11B Negative_regulation of CTSK 1 0.05 0.58 0.14 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Acro-osteolysis. They are ordered first by their pain relevance and then by number of times they were reported in Acro-osteolysis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT173578 Negative_regulation of CTSK 8 0.44 6.29 1.15 95.84
2 INT91527 Gene_expression of CTSK 38 0.78 22.21 7.42 88.64
3 INT121985 Positive_regulation of SLEB1 10 0.29 10.52 0.64 80.32
4 INT179788 Gene_expression of Sparc 42 0.77 19.96 2.57 72.56
5 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 71.28
6 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15 69.84
7 INT108306 Positive_regulation of TNFRSF11B 28 0.60 12.74 4.46 39.20
8 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 14.56
9 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 5.00
10 INT100861 Binding of CRP 179 0.48 175.2 26.45 5.00
11 INT23257 Regulation of CRP 127 0.62 100.05 21.87 5.00
12 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 5.00
13 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29 5.00
14 INT19965 Positive_regulation of COL1A1 23 0.45 14.49 4.38 5.00
15 INT158978 Localization of TNFRSF11B 19 0.78 11.8 3.32 5.00
16 INT4435 Gene_expression of PIK3C2A 20 0.77 14.43 2.48 5.00
17 INT153775 Positive_regulation of CTSK 9 0.52 5.44 1.9 5.00
18 INT182005 Positive_regulation of Gene_expression of CTSK 7 0.52 4.01 1.08 5.00
19 INT187155 Localization of SLEB1 3 0.05 2.83 0.9 5.00
20 INT153773 Regulation of Gene_expression of CTSK 2 0.34 1.36 0.62 5.00
21 INT133316 Localization of CTSK 5 0.52 2.43 0.43 5.00
22 INT182004 Regulation of Localization of CTSK 1 0.20 0.58 0.18 5.00
23 INT272225 Localization of Tgfbr2 1 0.29 0.74 0 5.00
24 INT272228 Localization of TGFBR1 1 0.34 0.74 0 5.00
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