D:Acromegaly

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Acromegalia, Acromegaly Disorder, Anterior Pituitary Adenoma Syndrome, Eosinophilic Adenoma Syndrome, Growth Hormone Hypersecretion Syndrome, Hypersecretion Syndrome Somatotropin Acromegaly, Hypersecretion Syndromes Somatotropin Acromegaly, Inappropriate Gh Secretion Syndrome, Inappropriate Gh Secretion Syndrome Acromegaly, Inappropriate Growth Hormone Secretion Syndrome, Inappropriate Growth Hormone Secretion Syndrome Acromegaly
Documents 291
Hot Single Events 200
Hot Interactions 23

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Acromegaly. They are ordered first by their relevance to Acromegaly and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT47221 Prl Regulation of Localization of Gh 1 0.28 0.27 0.46 99.84
2 INT17528 Prl Regulation of Gh 2 0.28 1.28 0.73 99.44
3 INT278020 Binding of Gh and Sst 1 0.18 0.16 0.15 99.16
4 INT316543 GH1 Regulation of Gene_expression of IGF1 1 0.03 1.32 0.09 99.12
5 INT278012 Gh Positive_regulation of Gene_expression of Ins1 1 0.11 1.24 0.26 99.12
6 INT47639 GH1 Positive_regulation of Prl 1 0.09 0.64 0.25 97.12
7 INT83235 SST Negative_regulation of Localization of GHRH 1 0.12 0.26 0.05 97.00
8 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37 96.84
9 INT47222 Binding of Gh and Prl 1 0.22 0.18 0.46 95.92
10 INT278016 Gh Positive_regulation of Localization of Ins1 1 0.16 1.22 0.26 95.76
11 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69 95.04
12 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77 94.92
13 INT239087 Binding of SST and Negative_regulation of Localization of GH1 1 0.19 0.36 0.24 91.84
14 INT278015 Gh Regulation of Ins1 1 0.10 1.47 0.27 90.36
15 INT198358 GH1 Regulation of Igf1 1 0.00 0.09 0.05 89.40
16 INT278018 Gh Negative_regulation of Phosphorylation of Ins1 1 0.13 1.5 0.29 87.44
17 INT136826 Gtf3a Regulation of Localization of Ggh 1 0.01 0.4 0 82.32
18 INT268798 Binding of Gh and Ghr 1 0.26 1.18 0.04 81.84
19 INT316546 Binding of GH1 and SST 2 0.03 0.55 0.54 81.16
20 INT316545 Binding of IGF1 and SST 1 0.06 0.45 0.37 81.04
21 INT308432 Binding of PDE4A and Aip 1 0.05 3.1 0.05 80.80
22 INT308426 Binding of Pde4a and Aip 1 0.02 0.89 0 80.80
23 INT303600 IGF1 Regulation of Gene_expression of GH1 1 0.39 0.83 0.14 80.08
24 INT7869 Gh Negative_regulation of IGF1 1 0.39 0.47 0.23 79.16
25 INT215035 Trh Positive_regulation of Gh 1 0.07 0.89 0 79.08
26 INT276141 Binding of Gh and Igf1 2 0.34 0.66 0.08 78.40
27 INT26468 Ghrh Positive_regulation of Localization of Gh 21 0.37 3.26 9.21 75.00
28 INT70570 su Positive_regulation of Gh 1 0.01 0.15 1.24 75.00
29 INT10844 Ghrh Regulation of Gh 13 0.13 4.77 4.71 75.00
30 INT32482 Ghrh Positive_regulation of Prl 3 0.18 0.26 1.62 75.00
31 INT52568 HTR1D Regulation of Localization of Gh 2 0.20 0.16 1.34 75.00
32 INT70568 su Negative_regulation of Ghrh Regulation of Gh 1 0.01 0.07 0.7 75.00
33 INT215036 Gh Positive_regulation of Gene_expression of Trh 1 0.08 1.4 0.06 70.48
34 INT268797 Ghrh Positive_regulation of Transcription of Gh 1 0.20 0.33 0.19 53.84
35 INT152429 Ghrh Positive_regulation of Localization of Gh 4 0.37 0.56 0.75 53.84
36 INT269769 Gh Regulation of Gene_expression of Igf1 1 0.04 0.98 0 52.76
37 INT339794 Sstr2 Positive_regulation of Gene_expression of Sstr5 1 0.08 0.25 0.64 51.04
38 INT156668 Gh Positive_regulation of Igf1 5 0.22 2.07 0.57 50.00
39 INT156667 Gh Positive_regulation of Gene_expression of Igf1 6 0.28 0.88 0.56 50.00
40 INT215037 Ghrh Regulation of Localization of Igf2 1 0.04 2.12 0.24 50.00
41 INT215034 Gh Regulation of Igf1 1 0.13 0.27 0.13 50.00
42 INT316552 Binding of SST and Sst1 1 0.03 0.53 0.09 50.00
43 INT278014 Ptprf Regulation of Localization of Gh 1 0.61 0.31 0 50.00
44 INT278017 Ptprf Regulation of Igf1 1 0.48 0.31 0 50.00
45 INT243468 Binding of SSTR1 and SSTR5 1 0.05 0.99 0.1 36.24
46 INT308425 Binding of Pde2a and Aip 1 0.04 1.37 0 36.20
47 INT350120 FSHR Regulation of CYP19A1 1 0.01 3.02 0 35.92
48 INT350116 FSHR Positive_regulation of Gene_expression of CGA 1 0.01 1.28 0 29.56
49 INT284891 FSHR Positive_regulation of Gene_expression of PLOD1 2 0.03 1.32 0.11 28.72
50 INT350117 GNRHR Negative_regulation of Localization of FSHR 1 0.01 1.06 0 25.00
51 INT350113 GNRHR Negative_regulation of Localization of PLOD1 1 0.01 1.06 0 25.00
52 INT350115 GNRH1 Negative_regulation of Localization of PLOD1 1 0.04 0.99 0 23.72
53 INT350122 GNRH1 Negative_regulation of Localization of FSHR 1 0.05 0.99 0 23.72
54 INT350119 Positive_regulation of GNRH1 Positive_regulation of PLOD1 1 0.04 0.86 0.03 20.84
55 INT350114 Positive_regulation of GNRH1 Positive_regulation of FSHR 1 0.05 0.86 0.03 20.84
56 INT45780 GNRH1 Positive_regulation of PLOD1 3 0.07 1.02 0.63 20.44
57 INT54584 GNRH1 Positive_regulation of FSHR 3 0.48 2.02 0.54 20.00
58 INT334918 GNRH1 Positive_regulation of Gene_expression of FSHR 2 0.11 1.27 0.03 20.00
59 INT265888 BCL2 Regulation of Gene_expression of BAD 1 0.04 1.08 0.1 9.60
60 INT265890 BCL2 Regulation of Gene_expression of BAX 1 0.04 1.08 0.1 9.60
61 INT265889 BAX Regulation of Gene_expression of BAD 1 0.06 1.08 0.1 9.60
62 INT290956 Binding of Slc3a1 and Lsd 1 0.03 0 0.51 5.00
63 INT263917 Binding of SST and Sstr5 2 0.02 0.56 0.45 5.00
64 INT191240 SAE1 Regulation of Localization of INS 1 0.08 1.15 0.3 5.00
65 INT290957 Lsd Positive_regulation of Gene_expression of Egr2 1 0.11 0.1 0.26 5.00
66 INT265886 IGF1 Positive_regulation of AKT1 1 0.11 3.06 0.23 5.00
67 INT197811 Binding of SMS and SST 1 0.00 0.98 0.21 5.00
68 INT191241 SST Regulation of SAE1 1 0.05 0.89 0.18 5.00
69 INT354195 Binding of GH1 and Sstr5 1 0.00 0.1 0.17 5.00
70 INT265892 IGF1 Positive_regulation of PIK3CG 1 0.18 1.96 0.16 5.00
71 INT354114 Binding of CALR and SST 1 0.01 0.1 0.16 5.00
72 INT207551 IGF1 Positive_regulation of Gene_expression of GH1 2 0.22 1.18 0.11 5.00
73 INT354194 Mtpn Negative_regulation of MIR524 1 0.00 0.08 0.11 5.00
74 INT288219 Cigs1 Regulation of Nrgn 1 0.00 0.87 0.1 5.00
75 INT243465 Binding of GH1 and GOPC 1 0.02 0.99 0.09 5.00
76 INT265887 IGF1 Negative_regulation of BCL2 1 0.09 1.02 0.09 5.00
77 INT239643 Binding of BCL2 and BCL2L11 3 0.16 2.26 0.09 5.00
78 INT265878 IGF1 Negative_regulation of Binding of BCL2 and BCL2L11 1 0.03 1.03 0.09 5.00
79 INT354120 Binding of IGF2 and IGFBP5 1 0.01 0.45 0.09 5.00
80 INT354124 Binding of IGF2 and IGFBP3 1 0.01 0.45 0.09 5.00
81 INT243466 POU1F1 Regulation of GH1 1 0.11 1.26 0.08 5.00
82 INT251469 INS Negative_regulation of Gene_expression of SHBG 2 0.11 4.11 0.08 5.00
83 INT243464 POU1F1 Regulation of PRL 1 0.28 1.26 0.08 5.00
84 INT354113 Binding of IGFBP3 and MIR524 1 0.01 0.69 0.07 5.00
85 INT354125 Binding of IGFBP3 and MIR15B 1 0.00 0.7 0.07 5.00
86 INT265883 IGF1 Positive_regulation of Transcription of FOXO1 1 0.17 1.14 0.07 5.00
87 INT196592 Binding of CFD and GHRH 1 0.02 1.88 0.07 5.00
88 INT265882 IGF1 Positive_regulation of Transcription of AKT1 1 0.08 1.13 0.07 5.00
89 INT207550 GH1 Regulation of Binding of GH1 and INS 1 0.22 0.55 0.07 5.00
90 INT354126 Binding of IGFALS and MIR125A 1 0.23 0.7 0.07 5.00
91 INT265877 IGF1 Regulation of Binding of GH1 and IGF1 1 0.03 0.47 0.07 5.00
92 INT354111 Binding of IGFBP3 and MIR125A 1 0.11 0.7 0.07 5.00
93 INT207552 Binding of GH1 and INS 1 0.23 0.55 0.07 5.00
94 INT354109 Binding of IGFALS and MIR15B 1 0.00 0.7 0.07 5.00
95 INT354116 Binding of IGFALS and MIR524 1 0.02 0.69 0.07 5.00
96 INT265893 BAD Regulation of FOXO1 1 0.03 1.08 0.06 5.00
97 INT350121 INS Negative_regulation of Positive_regulation of SHBG 1 0.09 1.48 0.04 5.00
98 INT350118 INS Negative_regulation of SHBG 1 0.09 1.42 0.04 5.00
99 INT207554 GH1 Negative_regulation of Phosphorylation of INS 1 0.26 0.28 0.03 5.00
100 INT265891 IGF1 Regulation of AKT1 1 0.05 1.24 0.03 5.00
101 INT265884 IGF1 Regulation of CREB1 1 0.13 1.31 0.03 5.00
102 INT207555 GH1 Negative_regulation of Phosphorylation of IRS1 1 0.10 0.28 0.03 5.00
103 INT265879 IGF1 Regulation of FOXO1 1 0.11 1.37 0.03 5.00
104 INT265880 IGF1 Regulation of PIK3CG 1 0.10 1.23 0.03 5.00
105 INT265881 GHRH Positive_regulation of GHR 1 0.05 0.05 0.03 5.00
106 INT265906 IGF1 Regulation of Gsk3b 1 0.25 1.31 0.03 5.00
107 INT207553 GH1 Negative_regulation of INS 1 0.27 0.28 0.03 5.00
108 INT197808 Binding of MEN1 and NME1 1 0.00 1.81 0 5.00
109 INT354123 MIR124-1 Negative_regulation of Gene_expression of CTDSP1 1 0.01 0.15 0 5.00
110 INT197809 Binding of MEN1 and VIM 1 0.04 0.52 0 5.00
111 INT197810 Binding of MEN1 and MUC1 1 0.06 0.47 0 5.00
112 INT354122 MIR126 Regulation of PIK3CG 1 0.03 2.01 0 5.00
113 INT197816 Binding of MEN1 and NFKB1 1 0.05 0.07 0 5.00
114 INT197813 Binding of AMBP and MEN1 1 0.00 0.51 0 5.00
115 INT243467 PCSK1 Positive_regulation of POMC 1 0.08 1.62 0 5.00
116 INT197812 Binding of AMBP and RDBP 1 0.00 0.51 0 5.00
117 INT354112 MIR126 Regulation of Localization of MIR381 1 0.01 0.7 0 5.00
118 INT197817 Binding of JUND and MEN1 1 0.18 0.14 0 5.00
119 INT197844 Binding of MEN1 and Nfkb1 1 0.06 0.26 0 5.00
120 INT354115 MIR222 Regulation of Gene_expression of CDKN1B 1 0.07 0.98 0 5.00
121 INT354127 MIR381 Regulation of GH1 1 0.00 0.69 0 5.00
122 INT354119 MIR381 Regulation of Localization of MIR126 1 0.01 0.7 0 5.00
123 INT354110 MIR126 Regulation of GH1 1 0.01 0.69 0 5.00
124 INT197815 Binding of MEN1 and TGFB1 1 0.16 0.13 0 5.00
125 INT197814 Binding of MEN1 and RELA 1 0.42 0.07 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Acromegaly. They are ordered first by their pain relevance and then by number of times they were reported in Acromegaly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 100.00
2 INT1893 Localization of Gh 1041 0.79 340.23 256.58 100.00
3 INT252 Localization of GH1 529 0.80 227.4 122.05 100.00
4 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 100.00
5 INT34741 Positive_regulation of Gene_expression of GH1 58 0.67 35.06 7.8 100.00
6 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 100.00
7 INT1530 Regulation of Gh 382 0.61 115.96 112.47 100.00
8 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45 100.00
9 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5 100.00
10 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56 100.00
11 INT425 Localization of PRL 455 0.81 189.64 144.8 100.00
12 INT158 Localization of Prl 2431 0.81 378.96 952.2 100.00
13 INT162 Regulation of Prl 794 0.62 165.01 322.24 100.00
14 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 100.00
15 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 100.00
16 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 100.00
17 INT148 Positive_regulation of Gnrhr 182 0.70 47.44 79.64 100.00
18 INT156666 Positive_regulation of Localization of Igf1 11 0.62 6.94 1.95 100.00
19 INT443 Localization of POMC 1020 0.81 284.52 443.17 100.00
20 INT954 Positive_regulation of Gene_expression of GHRH 18 0.50 7.6 1.63 100.00
21 INT692 Negative_regulation of SST 72 0.59 28.68 34.52 100.00
22 INT3215 Regulation of Gene_expression of Ins1 32 0.52 19.83 4.85 100.00
23 INT170601 Positive_regulation of Gene_expression of GOPC 122 0.43 42.79 11.68 100.00
24 INT156827 Localization of MRI1 25 0.65 16.06 8.33 100.00
25 INT248 Positive_regulation of Localization of GH1 137 0.69 49.25 32.92 99.98
26 INT14560 Regulation of Igf1 41 0.59 19.59 6.3 99.98
27 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 99.98
28 INT98805 Positive_regulation of Negative_regulation of GH1 2 0.36 1.43 0.06 99.98
29 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 99.96
30 INT182075 Negative_regulation of Positive_regulation of APEX1 1 0.13 0.63 0 99.96
31 INT13735 Negative_regulation of Regulation of GH1 14 0.42 4.35 5.39 99.96
32 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 99.92
33 INT255 Regulation of Localization of GH1 89 0.62 18.71 35.3 99.92
34 INT28861 Binding of Gh 61 0.46 25.61 6.38 99.92
35 INT695 Binding of POMC 304 0.48 56.66 126.85 99.92
36 INT34777 Localization of IGF1 82 0.80 42.68 8.62 99.88
37 INT9683 Binding of GH1 57 0.47 21.14 5.99 99.88
38 INT16130 Binding of IGF1 67 0.48 27.43 2.95 99.88
39 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 99.86
40 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 99.84
41 INT249 Localization of GHRH 215 0.80 78.02 51.87 99.84
42 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 99.84
43 INT986 Negative_regulation of Localization of GHRH 16 0.58 8.57 3.16 99.84
44 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 99.84
45 INT19 Regulation of Gnrhr 131 0.62 36.4 55.66 99.80
46 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 99.76
47 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9 99.76
48 INT182080 Localization of APEX1 2 0.57 2.3 0.05 99.76
49 INT5793 Binding of CTS 110 0.48 63.91 40.62 99.76
50 INT10841 Positive_regulation of Gene_expression of Gh 101 0.59 45.39 16.96 99.66
51 INT186142 Gene_expression of Ghrh 45 0.66 34.04 6.94 99.64
52 INT1309 Positive_regulation of Localization of Gnrhr 152 0.69 24.25 81.56 99.64
53 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 99.62
54 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52 99.62
55 INT67351 Positive_regulation of Localization of Ghr 2 0.44 0.78 0.23 99.62
56 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 99.60
57 INT135234 Regulation of ETFDH 13 0.29 10.8 3.4 99.58
58 INT921 Regulation of GH1 172 0.60 52.88 51.04 99.54
59 INT11729 Regulation of IGF1 71 0.61 44.58 9.71 99.54
60 INT9677 Negative_regulation of Gene_expression of GH1 46 0.48 23.32 3.68 99.52
61 INT5095 Localization of Ghrh 185 0.81 28.09 62.08 99.52
62 INT14009 Gene_expression of Sst 66 0.77 19.6 37.3 99.52
63 INT953 Positive_regulation of Positive_regulation of GHRH 17 0.67 2.38 8.18 99.48
64 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32 99.46
65 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 99.44
66 INT89772 Positive_regulation of APEX1 4 0.21 2.29 0.19 99.44
67 INT326 Gene_expression of Gnrhr 105 0.76 35.87 34.93 99.44
68 INT215026 Positive_regulation of Ppy 1 0.03 1.85 0.16 99.44
69 INT14559 Gene_expression of Igf1 254 0.78 112 34.17 99.38
70 INT462 Regulation of Pomc 157 0.62 41.67 67.27 99.38
71 INT182078 Gene_expression of APEX1 3 0.59 4.77 0.12 99.36
72 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51 99.28
73 INT873 Gene_expression of Gh1 130 0.76 26.15 46.75 99.28
74 INT397 Localization of SST 232 0.81 58.05 101.19 99.28
75 INT192300 Positive_regulation of Gene_expression of IGFBP1 6 0.60 2.85 0.81 99.28
76 INT239092 Positive_regulation of Binding of IGFBP1 1 0.04 0.6 0.04 99.28
77 INT231433 Positive_regulation of Binding of IGFBP3 2 0.34 0.6 0.04 99.28
78 INT48616 Positive_regulation of IGFBP1 14 0.43 5.62 1.56 99.28
79 INT172368 Negative_regulation of Binding of IGF1 3 0.42 1.57 0.18 99.28
80 INT239094 Negative_regulation of Binding of GH1 2 0.34 1.61 0.06 99.28
81 INT67349 Localization of Ghr 6 0.66 2.53 0.23 99.26
82 INT215029 Negative_regulation of Ghrh 15 0.56 11.37 2.62 99.24
83 INT215025 Negative_regulation of Gene_expression of Ghrh 10 0.41 7.8 0.65 99.24
84 INT27269 Localization of Ghrh 29 0.76 15.42 2.19 99.22
85 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 99.20
86 INT178840 Regulation of Localization of GOPC 5 0.25 0.78 0.14 99.20
87 INT1499 Negative_regulation of Gene_expression of Gh 58 0.42 25.17 7.86 99.10
88 INT8916 Regulation of Igf1 45 0.60 13.06 5.81 99.08
89 INT1782 Regulation of Gh1 125 0.62 22 55.74 99.08
90 INT278009 Phosphorylation of Sst 1 0.39 0.68 0.44 99.04
91 INT13063 Binding of RHCE 16 0.38 6.54 1.22 99.00
92 INT253 Regulation of PRL 184 0.62 47.27 65.79 98.96
93 INT15610 Localization of GOPC 223 0.65 68.26 28.7 98.96
94 INT12531 Localization of GANAB 3 0.09 2.79 0.26 98.92
95 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 98.90
96 INT4378 Regulation of Gene_expression of GH1 26 0.47 10.2 4.61 98.88
97 INT131187 Regulation of Gene_expression of IGF1 18 0.62 11.18 3.05 98.88
98 INT7867 Regulation of Negative_regulation of Gh 5 0.33 1.92 0.87 98.88
99 INT125578 Positive_regulation of Localization of IGF1 6 0.60 7.59 0.53 98.86
100 INT180250 Positive_regulation of GLUL 23 0.29 7.57 3.23 98.80
101 INT7365 Binding of Gh1 17 0.37 2.83 3.54 98.76
102 INT5135 Negative_regulation of GNRH1 106 0.58 36.63 27.71 98.76
103 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04 98.70
104 INT984 Positive_regulation of Localization of GHRH 58 0.70 12.66 16.51 98.58
105 INT66544 Binding of Igf1 23 0.46 8.33 2.44 98.48
106 INT19104 Regulation of Gene_expression of Gh 24 0.40 8.42 3.88 98.40
107 INT48726 Gene_expression of IGFBP1 27 0.67 9.45 3.36 98.40
108 INT178752 Binding of IGFBP1 8 0.15 4.58 0.61 98.40
109 INT3559 Negative_regulation of Localization of Gnrhr 73 0.58 18.89 26.41 98.28
110 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 98.24
111 INT18660 Binding of Gnrhr 45 0.41 10.6 16.85 98.20
112 INT70362 Transcription of GH1 9 0.56 2.01 0.69 98.16
113 INT916 Regulation of Localization of PRL 92 0.62 22.98 38.13 98.08
114 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 97.96
115 INT91774 Gene_expression of Nr3c1 27 0.78 16.14 10.7 97.92
116 INT131165 Positive_regulation of Gene_expression of Nr3c1 8 0.70 7.18 3.44 97.92
117 INT812 Localization of INS 1026 0.81 515.6 145.31 97.84
118 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 97.70
119 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 97.68
120 INT54836 Regulation of RHCE 9 0.30 6.68 0.47 97.64
121 INT115423 Gene_expression of Men1 4 0.47 14.08 0.64 97.60
122 INT142060 Positive_regulation of Ghrh 15 0.66 7.21 1.83 97.52
123 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 97.40
124 INT96077 Localization of DGCR2 1 0.02 0.32 0.24 97.36
125 INT10303 Regulation of STH 16 0.60 16.14 0.95 97.24
126 INT308431 Gene_expression of CNC 1 0.01 2.84 0.18 97.24
127 INT48725 Gene_expression of IGFBP3 128 0.78 78.83 8.19 97.20
128 INT78938 Binding of IGFBP3 40 0.45 27.95 1.73 97.20
129 INT11510 Negative_regulation of Positive_regulation of Gh 28 0.52 12.71 9.16 97.20
130 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 97.20
131 INT881 Negative_regulation of Localization of Gh1 164 0.58 15.1 75.28 97.12
132 INT876 Localization of Gh1 843 0.80 67.75 340.82 97.12
133 INT53906 Positive_regulation of Negative_regulation of Gh 9 0.50 6.72 2.73 97.12
134 INT200200 Positive_regulation of Negative_regulation of Igf1 3 0.47 2.33 0.22 97.12
135 INT16303 Negative_regulation of Localization of GH1 89 0.59 37.31 22.15 97.04
136 INT198357 Negative_regulation of Localization of Igf1 1 0.03 0.51 0.17 97.04
137 INT738 Regulation of POMC 459 0.62 111.19 243.74 97.00
138 INT151032 Localization of Igf1 49 0.76 26.32 5.71 96.96
139 INT200198 Regulation of Localization of Igf1 6 0.58 4.51 0.34 96.96
140 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45 96.90
141 INT7412 Positive_regulation of SST 71 0.70 24.44 29.48 96.90
142 INT1361 Negative_regulation of Gnrhr 118 0.58 57.77 35.54 96.88
143 INT59905 Gene_expression of Ghr 29 0.63 9.25 2.97 96.84
144 INT197832 Localization of MEN1 1 0.80 11.01 0.63 96.24
145 INT149448 Positive_regulation of Sstr5 2 0.46 0.73 0.33 96.24
146 INT173244 Positive_regulation of Sstr4 2 0.30 0.72 0.22 96.24
147 INT278003 Positive_regulation of Sstr1 1 0.31 0.72 0.09 96.24
148 INT9012 Localization of Vip 283 0.81 31.71 106.16 95.48
149 INT83236 Localization of PGR 14 0.73 8.26 2.23 95.40
150 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32 95.36
151 INT158836 Positive_regulation of Localization of TRH 7 0.49 2.61 0.67 95.32
152 INT7394 Positive_regulation of Localization of GNRH1 67 0.69 7.22 25.29 95.32
153 INT10009 Positive_regulation of TRH 31 0.67 8.94 11.03 95.32
154 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 95.28
155 INT5118 Regulation of SST 97 0.62 34.35 51.74 95.04
156 INT3214 Localization of Ins1 527 0.80 196.9 79.26 94.96
157 INT18323 Negative_regulation of Localization of Ins1 122 0.58 45.74 23.04 94.96
158 INT230810 Phosphorylation of Ins1 59 0.69 41.15 4.51 94.64
159 INT987 Localization of TRH 37 0.78 10.53 11.1 94.48
160 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 94.48
161 INT918 Positive_regulation of Localization of PRL 90 0.70 23.97 40.3 94.28
162 INT31412 Negative_regulation of Positive_regulation of Ins1 10 0.40 7.14 2.82 93.96
163 INT114091 Negative_regulation of Aip 6 0.48 4.16 1.3 93.76
164 INT9495 Negative_regulation of Gene_expression of Igf1 31 0.59 11.87 6.1 93.72
165 INT7414 Regulation of Localization of SST 31 0.60 4.85 17.46 93.48
166 INT75315 Regulation of Ghr 4 0.22 1.5 1.34 93.20
167 INT8747 Positive_regulation of Ins1 221 0.69 154.28 35.15 93.08
168 INT3614 Negative_regulation of Gene_expression of Gh1 16 0.42 6.8 5.74 93.00
169 INT187005 Positive_regulation of Gene_expression of Ghrh 9 0.48 8.02 0.29 92.76
170 INT8965 Positive_regulation of Trh 11 0.57 5.28 4.46 92.76
171 INT12292 Negative_regulation of Positive_regulation of GH1 22 0.58 5.02 8.28 92.56
172 INT253106 Negative_regulation of Phosphorylation of Ins1 6 0.17 5.62 0.87 92.48
173 INT6277 Positive_regulation of Gene_expression of Pomc 76 0.70 21.45 31.09 92.00
174 INT27266 Regulation of Gene_expression of Pomc 41 0.62 6.74 14.59 92.00
175 INT14506 Regulation of Sst 46 0.62 15.02 22.66 91.56
176 INT173236 Binding of Sstr2 8 0.25 1.64 2.41 91.56
177 INT278006 Binding of Sstr3 2 0.33 1.07 0.71 91.56
178 INT11735 Positive_regulation of HBN1 15 0.29 5.69 0.17 91.52
179 INT691 Binding of SST 67 0.48 24.66 32.67 91.36
180 INT47495 Protein_catabolism of Gh 2 0.98 0.68 1.08 91.28
181 INT45079 Binding of Ahr 21 0.44 10.07 1 91.24
182 INT16530 Gene_expression of Ghrh 45 0.77 6.22 13.44 91.12
183 INT26751 Regulation of Nr3c1 13 0.61 6.58 8.65 91.08
184 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24 91.04
185 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 90.76
186 INT268794 Binding of Prlr 1 0.02 0.16 0.11 90.64
187 INT38963 Binding of Lsd 7 0.41 1.91 4.12 90.36
188 INT3217 Regulation of Ins1 154 0.62 87.11 27.29 90.24
189 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 89.84
190 INT142174 Regulation of Gene_expression of Igf1 28 0.60 11.86 3.77 89.68
191 INT16869 Positive_regulation of Prl 24 0.70 15.7 7.63 89.60
192 INT956 Negative_regulation of PRL 94 0.59 42.72 23.01 89.60
193 INT3803 Negative_regulation of Igf1 45 0.58 15.95 7.98 89.60
194 INT10785 Gene_expression of Prl 35 0.78 20.64 6.7 89.60
195 INT178499 Positive_regulation of Gene_expression of Prl 6 0.29 3.78 0.49 89.60
196 INT1781 Negative_regulation of Gh1 127 0.59 16.94 51.77 89.60
197 INT62237 Gene_expression of Ptprf 2 0.65 1.63 1.08 89.60
198 INT215028 Phosphorylation of Gh 3 0.56 2.11 0.28 88.56
199 INT325236 Positive_regulation of Localization of Sstr2 2 0.25 0.81 0.22 88.00
200 INT68708 Negative_regulation of RHCE 4 0.26 2.53 0.48 87.68
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox