D:Acute Abdomen

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pChart

Disease Term
Synonyms ABDOMENS ACUTE, Acute Abdomens
Documents 938
Hot Single Events 25
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Acute Abdomen. They are ordered first by their relevance to Acute Abdomen and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT185092 CRP Positive_regulation of ESR1 1 0.06 2.83 0.28 96.40
2 INT347035 Binding of Kit and Cd34 1 0.02 1.38 0 71.24
3 INT249665 Binding of GOPC and PSS 1 0.02 3.13 0.21 5.00
4 INT249666 Binding of CD81 and GOPC 1 0.06 1.31 0 5.00
5 INT249664 Binding of CD81 and CHCHD2 1 0.00 2.51 0 5.00
6 INT193193 Binding of CRS and RAPH1 1 0.12 1.47 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Acute Abdomen. They are ordered first by their pain relevance and then by number of times they were reported in Acute Abdomen. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT36479 Binding of NR0B2 2 0.36 3.5 0.21 99.98
2 INT46383 Negative_regulation of TRGC1 42 0.55 44.03 6.2 99.34
3 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 99.28
4 INT44979 Positive_regulation of Pnp 11 0.59 5.61 2.41 98.92
5 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 98.64
6 INT3821 Negative_regulation of C1s 13 0.42 7.89 2.08 98.00
7 INT22024 Negative_regulation of HBG1 45 0.58 26 6.8 96.68
8 INT9188 Localization of HBG1 12 0.75 8.14 2.24 96.68
9 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 96.40
10 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 96.04
11 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 95.28
12 INT156827 Localization of MRI1 25 0.65 16.06 8.33 91.04
13 INT17114 Positive_regulation of AHSG 6 0.45 6 0.45 90.96
14 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 89.56
15 INT63536 Gene_expression of Syncrip 7 0.67 7.23 5.44 89.16
16 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 88.32
17 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 88.32
18 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 88.32
19 INT161383 Binding of AGK 1 0.32 0.68 0.08 87.28
20 INT88000 Gene_expression of LAP 15 0.55 6.94 0.91 86.32
21 INT185093 Binding of H2AFB3 1 0.01 2.8 0.2 85.88
22 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 85.16
23 INT182807 Localization of Cuzd1 2 0.49 1.38 0.14 84.80
24 INT129565 Negative_regulation of Cuzd1 5 0.43 0.65 1.24 82.32
25 INT6625 Negative_regulation of Pth 96 0.58 57.6 8.24 80.04
26 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 78.56
27 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 78.56
28 INT1829 Gene_expression of CFH 71 0.75 64.24 2.49 76.36
29 INT15689 Regulation of FAM49B 1 0.26 0.96 0.08 76.04
30 INT8798 Positive_regulation of Csrp1 61 0.69 63.86 14.14 75.00
31 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 75.00
32 INT55093 Negative_regulation of SPINK1 13 0.42 15.11 3.8 67.00
33 INT59784 Binding of DES 22 0.47 19.48 2.27 62.36
34 INT36798 Gene_expression of Mki67 178 0.77 132 8.24 61.16
35 INT83212 Positive_regulation of Gene_expression of Mki67 21 0.55 17.53 0.39 61.16
36 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 55.32
37 INT93399 Gene_expression of Ccnd1 38 0.58 21 3.65 55.32
38 INT193199 Gene_expression of RAPH1 6 0.60 4.55 0.36 55.04
39 INT15054 Gene_expression of Mme 48 0.77 42.52 10.63 53.52
40 INT66852 Gene_expression of Fcer2 15 0.14 9.74 1.27 53.52
41 INT574 Negative_regulation of C1S 9 0.47 11.25 1.41 50.00
42 INT72805 Negative_regulation of CFHR4 1 0.10 0.27 0 50.00
43 INT6557 Gene_expression of Eno2 65 0.77 54.42 8.17 47.04
44 INT116362 Positive_regulation of C4A 17 0.69 11.53 1.03 47.04
45 INT8224 Gene_expression of CHGA 73 0.75 53.63 12.31 43.96
46 INT36480 Localization of NR0B2 1 0.73 0.78 0.12 43.76
47 INT189852 Localization of H2-Q13 4 0.06 4.1 0.47 43.08
48 INT93396 Positive_regulation of Gene_expression of Ccnd1 13 0.52 8.59 2.26 41.52
49 INT3880 Negative_regulation of Serping1 54 0.58 37.19 4.75 40.72
50 INT180497 Binding of MRI1 45 0.42 28.35 14.77 40.68
51 INT193197 Localization of RAPH1 1 0.51 1.2 0 36.20
52 INT39865 Regulation of Positive_regulation of PLOD1 2 0.27 0.71 0.66 33.84
53 INT3933 Positive_regulation of PLOD1 128 0.70 30.76 42.03 32.24
54 INT226281 Regulation of TEK 1 0.60 1.33 0.11 26.52
55 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 26.32
56 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 17.16
57 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 10.16
58 INT73731 Binding of RAPH1 9 0.33 14.58 0.5 8.08
59 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 7.52
60 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 5.00
61 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 5.00
62 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
63 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68 5.00
64 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
65 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
66 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
67 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74 5.00
68 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
69 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 5.00
70 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92 5.00
71 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63 5.00
72 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 5.00
73 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24 5.00
74 INT47939 Gene_expression of Selp 171 0.76 87.54 39.03 5.00
75 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
76 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 5.00
77 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77 5.00
78 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48 5.00
79 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 5.00
80 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 5.00
81 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9 5.00
82 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78 5.00
83 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 5.00
84 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
85 INT10173 Binding of Tnf 45 0.48 35.6 14.32 5.00
86 INT92237 Positive_regulation of Gene_expression of CXCL10 43 0.70 43.67 13.65 5.00
87 INT15921 Positive_regulation of Serpine1 85 0.68 81.24 13.4 5.00
88 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 5.00
89 INT120828 Localization of CXCL10 29 0.68 18.01 12.17 5.00
90 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 5.00
91 INT19428 Gene_expression of MTRF1 42 0.08 27.17 10.43 5.00
92 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 5.00
93 INT23147 Negative_regulation of MRI1 26 0.38 14.33 8.96 5.00
94 INT20205 Binding of IgG 108 0.46 66.68 8.57 5.00
95 INT45914 Gene_expression of Apcs 22 0.65 24.25 8.48 5.00
96 INT24141 Negative_regulation of Apcs 24 0.59 16.82 8.29 5.00
97 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27 5.00
98 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71 5.00
99 INT5871 Binding of IFNA2 38 0.48 20.35 6.46 5.00
100 INT5254 Positive_regulation of Pla2g2a 22 0.68 10.42 6.37 5.00
101 INT79425 Gene_expression of SMN1 42 0.65 36.37 6.1 5.00
102 INT177467 Negative_regulation of MTRF1 22 0.05 11.84 5.57 5.00
103 INT38670 Positive_regulation of Gene_expression of KRT20 68 0.69 23.25 5.55 5.00
104 INT49805 Positive_regulation of MUC1 56 0.70 44.5 4.56 5.00
105 INT25334 Negative_regulation of Pla2g2a 16 0.56 9.01 4.23 5.00
106 INT88278 Binding of Kit 33 0.37 24.45 4.13 5.00
107 INT127667 Positive_regulation of Localization of CXCL10 5 0.59 5.89 4.09 5.00
108 INT23088 Phosphorylation of Tnf 15 0.79 9.85 3.82 5.00
109 INT45818 Gene_expression of C4A 35 0.75 26.4 3.52 5.00
110 INT76501 Binding of Selp 16 0.41 8.51 3.4 5.00
111 INT51607 Positive_regulation of DES 33 0.67 32.24 3.29 5.00
112 INT67379 Positive_regulation of Cd34 38 0.58 26.18 3.28 5.00
113 INT10353 Positive_regulation of PGR 34 0.70 21.84 3.28 5.00
114 INT3403 Positive_regulation of BCAR1 18 0.63 18.95 3.23 5.00
115 INT105884 Binding of Bcl2 19 0.35 15.67 3 5.00
116 INT36489 Regulation of Apcs 12 0.58 10.6 2.78 5.00
117 INT187851 Gene_expression of Hbb-ar 40 0.65 16.34 2.3 5.00
118 INT18007 Positive_regulation of C6orf25 23 0.66 14.98 1.95 5.00
119 INT15742 Negative_regulation of EPO 37 0.59 17.44 1.84 5.00
120 INT134443 Binding of Bax 10 0.47 5.62 1.84 5.00
121 INT23956 Negative_regulation of DES 12 0.42 10.84 1.82 5.00
122 INT216932 Positive_regulation of Negative_regulation of Il6 3 0.38 4.88 1.55 5.00
123 INT25020 Gene_expression of Pla2g2a 11 0.76 5.97 1.48 5.00
124 INT151450 Positive_regulation of Gene_expression of Kit 23 0.69 13.11 1.43 5.00
125 INT19483 Positive_regulation of Ppcs 3 0.37 14.1 1.36 5.00
126 INT24685 Localization of Serpine1 12 0.59 7.76 1.32 5.00
127 INT25336 Localization of Pla2g2a 5 0.72 4.97 1.17 5.00
128 INT15753 Negative_regulation of Ema 6 0.37 5.04 1.17 5.00
129 INT90670 Positive_regulation of KRT1 10 0.44 6.25 1.16 5.00
130 INT7207 Regulation of HBG1 27 0.60 22.1 1.12 5.00
131 INT47079 Localization of Apcs 4 0.75 7.28 1.11 5.00
132 INT222935 Negative_regulation of Localization of Apcs 1 0.21 3.02 0.97 5.00
133 INT19431 Positive_regulation of Gene_expression of MTRF1 5 0.05 3.13 0.95 5.00
134 INT153016 Gene_expression of nct 4 0.32 0.97 0.89 5.00
135 INT122813 Binding of Krt20 11 0.32 13.77 0.88 5.00
136 INT15870 Regulation of PSS 6 0.25 3.22 0.85 5.00
137 INT70027 Positive_regulation of Gene_expression of C6orf25 10 0.62 7.21 0.83 5.00
138 INT45913 Positive_regulation of Gene_expression of Apcs 3 0.40 5.27 0.83 5.00
139 INT144697 Regulation of Gene_expression of Bax 8 0.37 9.5 0.81 5.00
140 INT118254 Negative_regulation of Ppcs 4 0.39 2.49 0.79 5.00
141 INT274193 Negative_regulation of PES1 7 0.57 3.25 0.77 5.00
142 INT153015 Positive_regulation of Gene_expression of nct 3 0.24 0.9 0.74 5.00
143 INT222937 Binding of Apcs 3 0.19 4.76 0.74 5.00
144 INT183037 Gene_expression of MNX1 12 0.53 4.27 0.69 5.00
145 INT136531 Binding of Men1 8 0.47 9.62 0.65 5.00
146 INT193196 Regulation of MNX1 2 0.19 2.53 0.64 5.00
147 INT87458 Binding of CD81 4 0.18 6.02 0.59 5.00
148 INT184309 Positive_regulation of Llph 3 0.22 2.43 0.57 5.00
149 INT95692 Negative_regulation of KRT19 4 0.24 4.07 0.51 5.00
150 INT131931 Binding of KRT7 13 0.36 19.24 0.5 5.00
151 INT222936 Regulation of Localization of Apcs 1 0.23 1.52 0.49 5.00
152 INT222934 Regulation of Negative_regulation of Pla2g2a 1 0.21 1.51 0.49 5.00
153 INT214618 Transcription of FLNA 4 0.51 8.06 0.37 5.00
154 INT246502 Negative_regulation of Men1 2 0.30 8.9 0.33 5.00
155 INT222933 Positive_regulation of Binding of Apcs 1 0.22 2.6 0.28 5.00
156 INT258991 Gene_expression of Emb 2 0.43 2.55 0.23 5.00
157 INT258990 Localization of Emb 1 0.21 0.98 0.21 5.00
158 INT258989 Binding of Emb 1 0.10 0.98 0.21 5.00
159 INT79719 Negative_regulation of VAPA 6 0.43 2.94 0.21 5.00
160 INT184753 Binding of Pgd 2 0.17 2.38 0.17 5.00
161 INT219022 Positive_regulation of IgM 1:10240 1 0.01 1.44 0.16 5.00
162 INT76278 Binding of VAPA 4 0.48 3.32 0.16 5.00
163 INT108463 Binding of Ppcs 6 0.37 3.16 0.15 5.00
164 INT187656 Positive_regulation of RAPH1 1 0.31 1.73 0.14 5.00
165 INT331656 Localization of TRIM6-TRIM34 1 0.53 1.69 0.12 5.00
166 INT274191 Gene_expression of Ppcs 1 0.04 1.44 0.09 5.00
167 INT320168 Regulation of APH1A 1 0.00 1.56 0.08 5.00
168 INT274190 Positive_regulation of Binding of Ppcs 1 0.03 0.54 0.04 5.00
169 INT193195 Localization of MNX1 1 0.59 1.01 0.03 5.00
170 INT257384 Positive_regulation of Positive_regulation of C6orf25 2 0.14 2.17 0 5.00
171 INT249680 Binding of CHCHD2 1 0.01 2.45 0 5.00
172 INT193198 Positive_regulation of Binding of DES 1 0.18 0.49 0 5.00
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