D:Acute Chest Syndrome

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Disease Term
Synonyms Acute Chest Syndromes, Syndrome Acute Chest, Syndromes Acute Chest
Documents 173
Hot Single Events 66
Hot Interactions 3

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Acute Chest Syndrome. They are ordered first by their relevance to Acute Chest Syndrome and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT230455 FOXG1 Negative_regulation of HBS1L 1 0.02 1.73 0.18 97.20
2 INT160445 Tpsab1 Positive_regulation of Gene_expression of SPG21 1 0.48 0.96 0.48 93.72
3 INT160444 Tpsab1 Positive_regulation of Gene_expression of CEL 1 0.48 0.96 0.48 93.72
4 INT118300 Vwf Positive_regulation of Crp 1 0.00 0.87 0.3 75.76
5 INT149223 Binding of PHC3 and Suds3 1 0.03 0.44 0.07 74.76
6 INT149222 Binding of Fzd5 and Suds3 1 0.02 0.44 0.07 74.76
7 INT286901 Binding of HBM and VEGFA 1 0.05 1.08 0.14 5.00
8 INT286900 Binding of HBM and PDGFA 1 0.04 1.08 0.14 5.00
9 INT286898 Binding of HBM and IL6 1 0.01 1.09 0.14 5.00
10 INT286899 Binding of IL6 and CCL2 1 0.03 0.92 0.08 5.00
11 INT286902 Binding of PDGFA and VEGFA 1 0.24 1.1 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Acute Chest Syndrome. They are ordered first by their pain relevance and then by number of times they were reported in Acute Chest Syndrome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT170739 Gene_expression of Acsl1 8 0.65 7.02 0.5 100.00
2 INT170742 Positive_regulation of Acsl1 6 0.44 6.98 0.86 100.00
3 INT170737 Localization of Acsl1 5 0.20 3.51 0.38 100.00
4 INT170740 Localization of Scd1 1 0.17 0.99 0 100.00
5 INT152982 Negative_regulation of ACCS 14 0.37 9.63 1.3 100.00
6 INT310528 Negative_regulation of Positive_regulation of HRASLS 1 0.01 1.6 0.18 99.76
7 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01 99.68
8 INT49104 Positive_regulation of Gene_expression of Vcam1 30 0.69 36.52 7.64 99.68
9 INT49103 Positive_regulation of Vcam1 71 0.69 59.52 19.85 99.68
10 INT58301 Positive_regulation of Mpo 87 0.70 80.19 23.99 99.62
11 INT50595 Positive_regulation of HRASLS 16 0.49 9.65 4.24 99.20
12 INT170743 Negative_regulation of Gene_expression of Scd1 2 0.38 1.57 0 98.60
13 INT26073 Gene_expression of Scd1 17 0.70 9.17 0.47 98.30
14 INT17802 Transcription of Edn1 6 0.24 6.31 1.18 98.20
15 INT3915 Gene_expression of SCD 25 0.57 13.94 6 97.84
16 INT3816 Gene_expression of Ahr 13 0.65 7.51 1.31 97.84
17 INT153732 Positive_regulation of Gene_expression of SCD 9 0.47 3.28 0.29 97.84
18 INT153731 Positive_regulation of Gene_expression of Ahr 2 0.32 2 0.28 97.84
19 INT4464 Localization of CEL 21 0.80 8.09 3.88 97.84
20 INT5048 Binding of Edn1 55 0.47 18.86 19.16 97.68
21 INT70958 Binding of NOS3 19 0.37 11.84 3.29 97.68
22 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8 97.24
23 INT170741 Positive_regulation of Ccl27a 1 0.03 1.17 0.05 96.56
24 INT170733 Positive_regulation of Gene_expression of Ccl27a 1 0.03 1.17 0.05 96.56
25 INT170744 Positive_regulation of Transcription of Edn1 2 0.20 1.3 0.1 96.52
26 INT230456 Negative_regulation of Binding of HBS1L 1 0.05 1.73 0.18 96.52
27 INT40084 Binding of HBS1L 8 0.36 9.15 0.69 96.20
28 INT170736 Gene_expression of Ccl27a 3 0.48 2.05 0.47 96.16
29 INT76573 Negative_regulation of Vcam1 26 0.58 24.36 9.84 96.00
30 INT84264 Regulation of NPPB 22 0.61 21.18 1.94 95.24
31 INT170735 Positive_regulation of Gene_expression of Fcgr1 1 0.15 0.74 0 94.84
32 INT61912 Gene_expression of Fcgr1 3 0.69 1.13 0.41 94.44
33 INT36443 Regulation of Trf 4 0.61 1.65 1.18 93.76
34 INT52345 Regulation of Gene_expression of Epo 4 0.45 2.07 0.61 93.76
35 INT61207 Regulation of Gene_expression of Trf 1 0.02 0.79 0.09 93.76
36 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58 93.72
37 INT14598 Gene_expression of Tpsab1 40 0.73 14.55 5.4 93.72
38 INT74064 Gene_expression of SPG21 9 0.75 4.14 2.45 93.72
39 INT50740 Positive_regulation of SPG21 18 0.67 8.3 1.65 93.56
40 INT36263 Positive_regulation of CEL 53 0.69 34.88 12.87 93.36
41 INT14600 Positive_regulation of Tpsab1 51 0.68 22.1 7.7 93.16
42 INT36262 Positive_regulation of Tbce 35 0.49 28.79 14.33 92.80
43 INT87632 Positive_regulation of Gene_expression of PECAM1 32 0.45 29.47 4.66 91.48
44 INT15715 Positive_regulation of LTB 2 0.67 1.4 0.45 91.20
45 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 91.08
46 INT17101 Positive_regulation of Gene_expression of Edn1 24 0.69 24.9 8.86 90.68
47 INT62546 Positive_regulation of Gene_expression of Icam1 60 0.70 59.52 16.9 90.68
48 INT81444 Positive_regulation of Gene_expression of Vcam1 40 0.70 46.38 8.58 90.68
49 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43 90.24
50 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 90.24
51 INT73670 Gene_expression of Vcam1 128 0.78 123.79 24.96 90.24
52 INT12194 Gene_expression of Trf 38 0.69 18.1 4.56 90.00
53 INT9243 Gene_expression of FOXG1 14 0.53 7.52 1.02 87.72
54 INT114504 Positive_regulation of Scd1 10 0.48 3.77 0.8 87.04
55 INT98992 Binding of Vcam1 13 0.34 12.97 1.04 86.68
56 INT170738 Binding of Icam1 23 0.37 25.49 4.09 86.24
57 INT63043 Positive_regulation of Gene_expression of HBG2 6 0.48 1.75 0.26 85.84
58 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 85.52
59 INT16235 Positive_regulation of CGB 27 0.70 15.71 4.06 85.48
60 INT28521 Gene_expression of HBG2 56 0.77 16.62 8.64 85.32
61 INT3854 Binding of SCD 16 0.41 11.14 3.7 84.84
62 INT8773 Gene_expression of HBG1 58 0.76 37.6 4.59 83.76
63 INT2843 Gene_expression of Epo 100 0.78 62.01 14.66 83.56
64 INT55597 Negative_regulation of Gpx1 59 0.55 28.3 8.83 83.20
65 INT11064 Positive_regulation of NPR1 24 0.49 14.63 4.78 82.64
66 INT8772 Positive_regulation of Gene_expression of HBG1 16 0.68 6.93 0.95 80.04
67 INT37136 Transcription of Vwf 4 0.56 3.57 0.56 79.44
68 INT101924 Positive_regulation of Procr 1 0.07 0.69 0 77.96
69 INT16721 Negative_regulation of Cat 56 0.59 44.44 22.84 76.16
70 INT9210 Regulation of IL6 166 0.62 125.61 49.95 75.92
71 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 74.80
72 INT54895 Binding of Epo 24 0.48 11.38 4.48 72.88
73 INT46843 Binding of Trf 10 0.47 3.45 0.35 72.88
74 INT23219 Regulation of FOXG1 8 0.22 1.32 2.34 70.36
75 INT170734 Positive_regulation of Gene_expression of Scd1 5 0.48 5.87 0.13 67.52
76 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 64.12
77 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 63.72
78 INT24815 Binding of LDHA 9 0.36 6.73 0.89 55.68
79 INT113462 Localization of HPV18I2 1 0.58 1.42 0.06 52.32
80 INT14 Regulation of LDHA 22 0.57 15.26 2.14 51.32
81 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 50.00
82 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 25.92
83 INT41893 Negative_regulation of HBS1L 16 0.23 8.98 1.19 18.52
84 INT310526 Gene_expression of HFE2 2 0.32 1.14 0.09 13.20
85 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
86 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
87 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 5.00
88 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
89 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 5.00
90 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
91 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 5.00
92 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 5.00
93 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 5.00
94 INT86437 Binding of IL6 154 0.48 121.22 29.3 5.00
95 INT10835 Regulation of IL8 79 0.49 53.04 24.14 5.00
96 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 5.00
97 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 5.00
98 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03 5.00
99 INT14997 Positive_regulation of FPR1 21 0.66 9.82 13.2 5.00
100 INT8548 Gene_expression of HP 86 0.77 47.62 11.94 5.00
101 INT2339 Positive_regulation of CB 30 0.29 10.68 9.12 5.00
102 INT131788 Positive_regulation of NPPB 87 0.67 86.1 8.81 5.00
103 INT30443 Positive_regulation of AIS 30 0.54 22.59 7.2 5.00
104 INT147583 Gene_expression of AIS 82 0.58 48.7 7.11 5.00
105 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9 5.00
106 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 5.00
107 INT128406 Gene_expression of Pax1 11 0.60 7.18 5.91 5.00
108 INT41892 Gene_expression of HBM 48 0.64 28.32 5.64 5.00
109 INT102583 Gene_expression of Gdf15 26 0.77 15.33 4.52 5.00
110 INT18995 Binding of CEL 23 0.47 14.46 4.5 5.00
111 INT73611 Negative_regulation of SCD 15 0.37 26.67 3.71 5.00
112 INT98068 Gene_expression of SCN2A 19 0.75 14.42 3.31 5.00
113 INT102585 Positive_regulation of Gdf15 19 0.69 14.78 3.21 5.00
114 INT14447 Localization of F2 20 0.79 12.77 2.67 5.00
115 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5 5.00
116 INT102582 Positive_regulation of Gene_expression of Gdf15 11 0.69 7.66 1.68 5.00
117 INT94827 Gene_expression of HBS1L 24 0.67 26.11 1.61 5.00
118 INT93956 Binding of HBM 20 0.35 8.86 1.48 5.00
119 INT132453 Binding of TF 31 0.36 12.98 1.22 5.00
120 INT205995 Gene_expression of SLC7A7 11 0.75 10.61 1.21 5.00
121 INT210392 Regulation of PDGFA 10 0.36 11.41 1.12 5.00
122 INT159446 Negative_regulation of Gdf15 5 0.58 3.36 1 5.00
123 INT204156 Gene_expression of HAMP 7 0.75 8.1 0.94 5.00
124 INT21660 Regulation of CHM 14 0.61 8.51 0.93 5.00
125 INT188317 Positive_regulation of Gene_expression of PDGFA 15 0.46 12.7 0.91 5.00
126 INT95118 Negative_regulation of Gene_expression of PDGFA 4 0.54 5.03 0.76 5.00
127 INT210390 Binding of PDGFA 12 0.36 6.78 0.63 5.00
128 INT52347 Negative_regulation of CHM 17 0.58 13.03 0.59 5.00
129 INT255313 Positive_regulation of Positive_regulation of AIS 2 0.04 3.83 0.55 5.00
130 INT310529 Positive_regulation of MDFIC 1 0.05 6.21 0.52 5.00
131 INT297528 Transcription of HAMP 3 0.69 3.64 0.5 5.00
132 INT240020 Regulation of Binding of IL6 4 0.36 4.38 0.46 5.00
133 INT228685 Negative_regulation of Gene_expression of SCD 2 0.26 1.64 0.38 5.00
134 INT50530 Binding of MDFIC 2 0.17 1.88 0.38 5.00
135 INT306940 Positive_regulation of HAMP 3 0.49 5.06 0.36 5.00
136 INT241859 Protein_catabolism of SLC40A1 2 0.02 1.22 0.31 5.00
137 INT310527 Gene_expression of MDFIC 1 0.05 1.87 0.29 5.00
138 INT310513 Gene_expression of Twsg1 1 0.17 3.97 0.28 5.00
139 INT310530 Positive_regulation of Gene_expression of HAMP 3 0.49 4.16 0.28 5.00
140 INT243267 Positive_regulation of SLC40A1 4 0.41 2.72 0.22 5.00
141 INT241863 Binding of SLC40A1 4 0.28 3.86 0.22 5.00
142 INT308962 Regulation of SLC7A7 3 0.16 1.2 0.18 5.00
143 INT195213 Positive_regulation of Gene_expression of HBS1L 4 0.15 3.5 0.16 5.00
144 INT310523 Localization of MDFIC 1 0.05 0.83 0.14 5.00
145 INT192918 Negative_regulation of HAMP 3 0.57 2.29 0.09 5.00
146 INT310525 Negative_regulation of Gene_expression of HAMP 1 0.57 0.58 0.08 5.00
147 INT310522 Regulation of Transcription of HAMP 1 0.60 1.36 0.05 5.00
148 INT286904 Regulation of Binding of PDGFA 1 0.30 0.74 0.04 5.00
149 INT296384 Regulation of SLC40A1 2 0.01 0.83 0.03 5.00
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