D:Acute Necrotizing Pancreatitis

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pChart

Disease Term
Synonyms Necrotizing Pancreatitis Acute
Documents 61
Hot Single Events 53
Hot Interactions 4

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Acute Necrotizing Pancreatitis. They are ordered first by their relevance to Acute Necrotizing Pancreatitis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT184608 APC Regulation of Gene_expression of Nppa 1 0.06 1.11 0.12 100.00
2 INT142418 Lep Positive_regulation of Gene_expression of Ghrl 1 0.48 1.66 0.09 98.76
3 INT177359 Serpinc1 Positive_regulation of CSRP1 1 0.00 0.97 0.72 86.92
4 INT184603 APC Negative_regulation of Gene_expression of TNF 1 0.09 0.97 0.13 86.72
5 INT352521 Cnn1 Positive_regulation of Cp 1 0.00 1.45 0.5 46.96
6 INT181490 Tryptase Positive_regulation of F2rl1 1 0.13 1.83 1.21 24.36
7 INT181491 Tryptase Positive_regulation of HTR1A 1 0.02 0.93 0.61 24.36
8 INT177358 Ptger1 Positive_regulation of Localization of AMY2A 1 0.00 0.56 0.54 5.00
9 INT177357 Ptger1 Positive_regulation of Gene_expression of AMY2A 1 0.00 0.56 0.54 5.00
10 INT334106 APC Negative_regulation of NFKB1 1 0.25 1.37 0.17 5.00
11 INT334108 APC Negative_regulation of TNF 1 0.13 1.36 0.17 5.00
12 INT334107 Binding of APC and APCS 1 0.16 1.52 0.04 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Acute Necrotizing Pancreatitis. They are ordered first by their pain relevance and then by number of times they were reported in Acute Necrotizing Pancreatitis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT5623 Positive_regulation of Nppa 174 0.70 69.96 52.33 100.00
2 INT82079 Positive_regulation of Lep 79 0.70 40 11.07 100.00
3 INT5622 Gene_expression of Nppa 101 0.78 49.46 25.31 100.00
4 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47 100.00
5 INT142417 Positive_regulation of Transcription of Lep 2 0.52 2.63 0.22 100.00
6 INT6196 Regulation of Nppa 83 0.62 30.31 30.18 100.00
7 INT113456 Binding of Lpl 2 0.36 0.81 0.28 99.98
8 INT61893 Gene_expression of Ghrl 125 0.75 71.49 15.14 99.84
9 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08 99.84
10 INT83392 Transcription of Lep 6 0.54 5.07 2.04 99.68
11 INT1928 Negative_regulation of Lpl 18 0.51 11.22 2.49 99.66
12 INT8027 Regulation of Gene_expression of Ngf 34 0.62 26.32 31.16 99.44
13 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 99.22
14 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 98.84
15 INT107291 Positive_regulation of Ghrl 58 0.67 44.6 9.68 98.76
16 INT65712 Positive_regulation of Localization of ICAM1 14 0.70 16.72 5.5 98.60
17 INT65713 Localization of ICAM1 42 0.81 39.55 11.49 98.60
18 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76 98.40
19 INT63121 Binding of APC 29 0.41 23.02 3.8 97.92
20 INT24122 Positive_regulation of Ltf 9 0.61 5.33 2.44 97.80
21 INT27598 Negative_regulation of Pttg1ip 5 0.36 2.04 1.1 96.96
22 INT16631 Negative_regulation of APC 46 0.57 30.53 7.11 96.24
23 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 95.20
24 INT1060 Negative_regulation of Pla2g1b 50 0.57 22.91 18.12 93.88
25 INT2541 Binding of Calca 200 0.48 67.14 134.62 93.36
26 INT184604 Negative_regulation of Pla2g3 2 0.02 1.85 0.39 93.36
27 INT117855 Negative_regulation of Ghrl 29 0.57 17.52 5 93.04
28 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 93.00
29 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38 92.56
30 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 91.52
31 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03 91.52
32 INT18515 Gene_expression of Lipg 18 0.66 9.3 3.72 91.40
33 INT6852 Localization of TNF 883 0.81 705.95 270.84 91.24
34 INT19511 Localization of Il6 212 0.81 118.17 67.67 91.24
35 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76 91.24
36 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 90.16
37 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 89.36
38 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 89.16
39 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2 89.16
40 INT4895 Positive_regulation of Gene_expression of Tac4 16 0.69 2.46 11.51 89.16
41 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 88.28
42 INT57057 Gene_expression of APC 131 0.78 122.24 8.7 88.08
43 INT3034 Localization of Ngf 126 0.81 50.81 72.84 87.60
44 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56 87.12
45 INT50050 Gene_expression of CSRP1 23 0.76 16.84 5.86 86.92
46 INT4887 Gene_expression of Tac4 70 0.77 11.66 40.97 86.84
47 INT6133 Negative_regulation of Serpinc1 56 0.58 42.8 8.35 86.04
48 INT24410 Negative_regulation of Gene_expression of Serpinc1 4 0.28 1.98 0.91 86.04
49 INT10147 Gene_expression of Serpinc1 28 0.76 17.73 5.77 85.64
50 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 85.52
51 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01 81.84
52 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 80.08
53 INT30738 Negative_regulation of Gene_expression of ALB 32 0.59 19.01 5.04 80.08
54 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 79.40
55 INT178221 Negative_regulation of Gene_expression of HBG1 3 0.33 2.43 0.13 79.12
56 INT8773 Gene_expression of HBG1 58 0.76 37.6 4.59 78.16
57 INT48933 Gene_expression of Mapk3 93 0.75 44.39 37.92 77.28
58 INT56032 Positive_regulation of NCAM1 38 0.49 26.01 4.68 76.16
59 INT10534 Positive_regulation of Trib3 209 0.60 78.75 81.48 74.96
60 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 74.32
61 INT80685 Gene_expression of MAPK8 90 0.72 51.91 13.36 74.16
62 INT171924 Gene_expression of MAPK14 60 0.65 54.38 21.68 73.12
63 INT209936 Negative_regulation of Gene_expression of MAPK14 7 0.20 4.95 0.53 73.12
64 INT73641 Regulation of Lep 45 0.62 26.2 12.59 71.40
65 INT35251 Regulation of Ghrl 21 0.60 8.26 2.6 70.96
66 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 64.16
67 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28 60.08
68 INT1634 Gene_expression of Gcg 25 0.75 14.98 4.42 59.36
69 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 58.56
70 INT20210 Localization of Ngf 69 0.79 46.22 38.57 51.00
71 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67 46.44
72 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 43.24
73 INT27954 Positive_regulation of Gene_expression of Ngf 87 0.70 57.91 51.96 43.24
74 INT48238 Regulation of Gene_expression of Ngf 25 0.62 11.48 16.42 43.24
75 INT48253 Positive_regulation of AMY2A 8 0.59 3.86 1.79 39.52
76 INT37168 Positive_regulation of APCS 22 0.67 9.61 4.59 39.04
77 INT56448 Regulation of ICAM1 52 0.60 55.1 10.96 30.56
78 INT63365 Gene_expression of Spg21 21 0.65 12.9 7.37 29.04
79 INT12010 Gene_expression of Cp 38 0.65 20.55 7.84 28.56
80 INT49488 Gene_expression of mMCP-7 37 0.75 26.11 7.68 28.08
81 INT184605 Positive_regulation of Transcription of APC 2 0.19 2.39 0.33 27.84
82 INT118243 Transcription of APC 4 0.45 3.33 0.33 27.44
83 INT59365 Gene_expression of HTR1A 41 0.75 16.31 16.57 21.24
84 INT190611 Gene_expression of Cnn1 13 0.56 5.87 0.75 14.40
85 INT181489 Localization of Spg21 16 0.12 10.89 6.84 11.08
86 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 5.00
87 INT31186 Negative_regulation of Insrr 81 0.37 24.91 55.94 5.00
88 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 5.00
89 INT56072 Negative_regulation of NFKB1 94 0.59 53.16 28.19 5.00
90 INT288 Positive_regulation of Sct 88 0.70 32.83 24.5 5.00
91 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 5.00
92 INT23257 Regulation of CRP 127 0.62 100.05 21.87 5.00
93 INT2432 Positive_regulation of Cp 41 0.67 31.1 16.68 5.00
94 INT3466 Gene_expression of Ptger1 39 0.75 18.34 15.75 5.00
95 INT9783 Gene_expression of INSRR 81 0.50 32.99 15.52 5.00
96 INT181488 Positive_regulation of Spg21 13 0.12 15.52 10.03 5.00
97 INT67101 Gene_expression of DST 47 0.54 25.92 9.59 5.00
98 INT93110 Regulation of CDCP1 16 0.03 7.98 3.83 5.00
99 INT124185 Negative_regulation of Kit 57 0.59 35.43 3.61 5.00
100 INT102076 Regulation of DST 15 0.22 10 3.5 5.00
101 INT2464 Gene_expression of AMY2A 21 0.75 13.76 2.78 5.00
102 INT1957 Localization of AMY2A 6 0.68 2.85 1.31 5.00
103 INT155992 Gene_expression of THBD 16 0.66 17 1.24 5.00
104 INT7207 Regulation of HBG1 27 0.60 22.1 1.12 5.00
105 INT13948 Positive_regulation of Amy1a 2 0.44 2.1 0.91 5.00
106 INT57596 Regulation of Gene_expression of ALB 9 0.44 5.44 0.91 5.00
107 INT68447 Positive_regulation of PDP1 11 0.64 5.69 0.83 5.00
108 INT57062 Regulation of APC 24 0.58 14.3 0.7 5.00
109 INT94381 Negative_regulation of Col4a2 2 0.31 0.57 0.43 5.00
110 INT200744 Regulation of Gene_expression of DST 5 0.20 2.64 0.36 5.00
111 INT291134 Gene_expression of PDP1 4 0.62 0.64 0.26 5.00
112 INT250992 Regulation of Gene_expression of INSRR 2 0.00 1.22 0.24 5.00
113 INT68448 Negative_regulation of Positive_regulation of PDP1 4 0.40 1.84 0.24 5.00
114 INT222650 Gene_expression of Col4a2 6 0.19 1.84 0.19 5.00
115 INT45767 Regulation of Phb 2 0.26 0.26 0.13 5.00
116 INT287757 Gene_expression of Phb 2 0.65 0.26 0.05 5.00
117 INT334117 Regulation of Gene_expression of HBG1 1 0.03 0.96 0.04 5.00
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