D:Acute Renal Failure

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Disease Term
Synonyms Acute Kidney Failure, Acute Kidney Failures, Acute Kidney Insufficiencies, ACUTE KIDNEY INSUFFICIENCY, Acute Renal Failure Disorder, Acute Renal Failure Syndrome, Acute Renal Failures, ACUTE RENAL INSUFFICIENCY, Acute Renal Shutdown, Acute Renal Shutdowns, Kidney Failure Acute
Documents 1409
Hot Single Events 200
Hot Interactions 14

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Acute Renal Failure. They are ordered first by their relevance to Acute Renal Failure and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT136855 Arf5 Positive_regulation of Cdkn2a 1 0.07 1.8 0.15 100.00
2 INT136856 Cdkn2a Positive_regulation of Arf5 1 0.01 0.9 0.08 100.00
3 INT254089 EPO Regulation of Gene_expression of Bcl2 1 0.03 0.63 0 99.98
4 INT254090 EPO Negative_regulation of Gene_expression of Bax 1 0.10 0.63 0 99.98
5 INT83425 Binding of CD40LG and IGHG3 11 0.21 4.56 2.09 98.72
6 INT254091 EPO Positive_regulation of Gene_expression of Bcl2l1 1 0.11 0.66 0 93.80
7 INT136096 Binding of CFH and CFI 1 0.04 2.28 0.05 92.56
8 INT316203 Ghsr Positive_regulation of Transcription of Agrp 1 0.02 1.5 0.19 91.24
9 INT193492 Binding of Icam1 and Sele 1 0.06 1.05 0.34 86.56
10 INT260397 Positive_regulation of Hmox1 Positive_regulation of Gene_expression of Adipoq 1 0.37 0.78 0.22 86.52
11 INT260394 Positive_regulation of Hmox1 Positive_regulation of Adipoq 1 0.37 0.78 0.19 86.52
12 INT281322 Binding of PLEK and Tlr4 1 0.15 1.41 0 83.04
13 INT132318 Ghrl Positive_regulation of Localization of GH1 5 0.32 4.49 0.84 82.32
14 INT117202 Binding of GFER and Mefv 1 0.03 2.01 0.28 82.00
15 INT349583 Aap Positive_regulation of Gene_expression of Cyp2e1 1 0.18 1.57 3.59 79.32
16 INT328299 Binding of GHRH and GHS 1 0.07 2.21 0.31 77.76
17 INT20587 Nppa Positive_regulation of Gfra1 1 0.02 0.32 0.26 75.00
18 INT209615 Binding of KRT20 and Cd34 1 0.00 1.05 0.06 73.36
19 INT209611 Binding of Mme and Cd34 1 0.00 1.05 0.06 73.36
20 INT209610 Binding of Cd22 and Cd34 1 0.01 1.05 0.06 73.36
21 INT349592 GTF2H5 Negative_regulation of Cyp2c22 1 0.00 0.64 0.98 72.24
22 INT203009 Binding of Cpb1 and Dob2 1 0.02 0.77 0 69.60
23 INT281317 Stx2 Regulation of Gene_expression of tf 1 0.11 1.45 0.03 68.60
24 INT281313 Tlr4 Regulation of Gene_expression of tf 1 0.05 1.45 0.03 68.60
25 INT283226 Binding of ACE and CC2D1A 1 0.11 2.37 0.04 65.84
26 INT258018 Binding of AGT and RASGRP1 1 0.00 1.59 0.1 65.28
27 INT207783 Binding of MRC1 and Ap3d1 1 0.00 2.54 0.22 65.20
28 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19 64.64
29 INT258014 Binding of ANGPT2 and RASGRP1 1 0.00 1.58 0.1 64.64
30 INT297311 Casp1 Positive_regulation of Il18 1 0.09 1.02 0.55 63.04
31 INT108546 BCL2L10 Regulation of MAPKAPK5 1 0.03 1.22 1.1 61.44
32 INT314756 IL6 Positive_regulation of Gene_expression of Crp 2 0.13 4.58 0.48 60.20
33 INT108547 AKT1 Regulation of MAPKAPK5 1 0.04 1.2 1.08 59.80
34 INT315369 Binding of IL6 and Crp 1 0.10 2.09 0.3 55.80
35 INT281305 Binding of St8sia2 and Tlr4 1 0.02 0.98 0 54.92
36 INT297316 Negative_regulation of Rock2 Positive_regulation of Cdh1 1 0.01 1.92 0.43 47.68
37 INT64242 Binding of Gast and TSS 1 0.08 1.73 0.09 45.28
38 INT281319 Binding of F7 and tf 1 0.24 1 0.16 37.36
39 INT252646 Binding of C6orf25 and SYT16 1 0.00 0.51 0.17 28.80
40 INT260392 Hmox1 Positive_regulation of Adipoq 1 0.32 0.65 0.07 26.32
41 INT281302 Binding of Itgam and Fgg 1 0.00 0.62 0.15 14.24
42 INT281315 Binding of Gp1bb and Itgam 1 0.00 0.62 0.15 10.40
43 INT281321 STX1A Positive_regulation of Gene_expression of tf 1 0.07 0.96 0 9.40
44 INT281310 Stx2 Positive_regulation of Gene_expression of tf 1 0.20 0.89 0 6.24
45 INT281300 Tlr4 Positive_regulation of Gene_expression of tf 1 0.12 2.5 0 5.76
46 INT328363 Ghrl Negative_regulation of PLOD1 1 0.02 0.11 0.04 5.64
47 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47 5.00
48 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
49 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27 5.00
50 INT349584 Binding of Cyp2e1 and Aap 1 0.10 1.56 3.24 5.00
51 INT349589 Aap Positive_regulation of Cyp2e1 1 0.21 1.84 2.71 5.00
52 INT349585 Aap Positive_regulation of Etf1 1 0.00 1.68 1.94 5.00
53 INT113550 Binding of FN1 and VTN 6 0.30 5.24 1.91 5.00
54 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9 5.00
55 INT349588 Aap Positive_regulation of Gene_expression of Ros1 1 0.06 0.73 1.85 5.00
56 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61 5.00
57 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53 5.00
58 INT293009 IRF6 Positive_regulation of Positive_regulation of CA2 1 0.04 0.66 1.49 5.00
59 INT293013 IL8 Positive_regulation of Positive_regulation of CA2 1 0.12 0.66 1.49 5.00
60 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47 5.00
61 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2 5.00
62 INT349587 Binding of Aap and Csf2 1 0.04 0.41 1.18 5.00
63 INT349586 Aap Regulation of Gene_expression of Ros1 1 0.03 0.56 1.17 5.00
64 INT349590 Aap Positive_regulation of Cytl1 1 0.13 1.31 1.15 5.00
65 INT349576 Binding of Ugt2b and Sult1a1 1 0.00 0.45 1.03 5.00
66 INT293014 IRF6 Positive_regulation of Localization of CA2 1 0.04 0.71 1.02 5.00
67 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
68 INT293008 IL8 Positive_regulation of Localization of CA2 1 0.11 0.71 1.01 5.00
69 INT293011 GPM6A Regulation of GOPC 1 0.00 0 0.81 5.00
70 INT81716 ITGAL Regulation of ITGB2 2 0.30 1.24 0.78 5.00
71 INT183698 Binding of Cxcr2 and Cxcl1 3 0.33 3.26 0.76 5.00
72 INT170127 Binding of ITGAL and PECAM1 2 0.01 2.71 0.75 5.00
73 INT248271 IL6 Regulation of Gene_expression of Crp 3 0.27 1.7 0.73 5.00
74 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69 5.00
75 INT297307 Negative_regulation of Binding of Ccr1 and Ccl3 1 0.27 0.73 0.67 5.00
76 INT297313 Negative_regulation of Binding of Ccr1 and Ccl5 1 0.28 0.74 0.67 5.00
77 INT293010 ELANE Regulation of Localization of LTF 1 0.00 0.54 0.67 5.00
78 INT352496 AVP Regulation of Gene_expression of CRS 1 0.27 2.47 0.59 5.00
79 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5 5.00
80 INT300956 Il4 Negative_regulation of IL8 1 0.02 0.37 0.48 5.00
81 INT300960 Il4 Negative_regulation of IL1B 1 0.03 0.37 0.48 5.00
82 INT300957 Binding of IL13 and Il4 1 0.01 0.58 0.48 5.00
83 INT300959 Il4 Negative_regulation of TNF 1 0.03 0.37 0.48 5.00
84 INT300955 Il4 Negative_regulation of Il6 1 0.03 0.37 0.48 5.00
85 INT222284 Negative_regulation of Casp1 Negative_regulation of Il18 1 0.01 0.79 0.46 5.00
86 INT246938 Binding of Tlr4 and Tlr2 3 0.39 2.88 0.46 5.00
87 INT222283 Negative_regulation of Casp1 Negative_regulation of Il1a 1 0.00 0.78 0.46 5.00
88 INT242401 Negative_regulation of Bdkrb1 Negative_regulation of Gene_expression of Mcpt1 1 0.16 1.45 0.46 5.00
89 INT242402 Negative_regulation of Bdkrb1 Positive_regulation of Hmox1 1 0.17 1.44 0.45 5.00
90 INT328385 Binding of GHS and Ghrl 1 0.15 1.89 0.45 5.00
91 INT328377 Binding of GAST and Ghrl 1 0.03 0.62 0.43 5.00
92 INT293007 IRF6 Positive_regulation of ELANE 1 0.00 0 0.42 5.00
93 INT181862 Binding of MPO and PRTN3 2 0.16 1.18 0.38 5.00
94 INT297314 Binding of Bsg and Sele 1 0.11 1.37 0.37 5.00
95 INT242403 INSR Positive_regulation of Gene_expression of Bdkrb1 1 0.45 0.88 0.35 5.00
96 INT241742 Negative_regulation of Sdhb Regulation of Rapgef5 1 0.02 0.39 0.33 5.00
97 INT318299 Binding of F2 and PRTN3 1 0.01 1.92 0.33 5.00
98 INT226716 Binding of Cxcr4 and Sdf2l1 2 0.30 1.42 0.32 5.00
99 INT311228 DPP4 Negative_regulation of Localization of GLP1R 1 0.31 1.25 0.32 5.00
100 INT241740 Sdhb Regulation of Rapgef5 1 0.02 0.34 0.32 5.00
101 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31 5.00
102 INT241739 Sdhb Regulation of Adora2b 1 0.04 0.63 0.31 5.00
103 INT242399 Cyp19a1 Negative_regulation of Gene_expression of Bad 1 0.00 1.32 0.31 5.00
104 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3 5.00
105 INT170128 Binding of ITGAL and ITGB2 2 0.04 1.6 0.28 5.00
106 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28 5.00
107 INT344402 Binding of Crp and Spp1 1 0.05 2.92 0.28 5.00
108 INT328378 GH1 Regulation of Gene_expression of Ghrl 1 0.02 0.39 0.25 5.00
109 INT300958 IL1B Positive_regulation of Il6 1 0.04 0.25 0.25 5.00
110 INT312726 AASS Positive_regulation of FGD1 1 0.02 0.08 0.24 5.00
111 INT328382 Positive_regulation of Ghrl Positive_regulation of Localization of INS 1 0.03 1.08 0.23 5.00
112 INT207845 Binding of INS and Hypism 3 0.04 2.88 0.22 5.00
113 INT255044 GLP1R Positive_regulation of Localization of INS 3 0.49 1.47 0.22 5.00
114 INT355503 Positive_regulation of SCN10A Positive_regulation of Localization of NPY 1 0.17 1.32 0.22 5.00
115 INT318303 Negative_regulation of Myoz1 Negative_regulation of Transcription of IL2 1 0.00 0.75 0.21 5.00
116 INT241822 Binding of CD4 and HIVEP1 3 0.01 2.73 0.21 5.00
117 INT327112 HCCS Positive_regulation of Gene_expression of SLCO1B3 1 0.03 0.65 0.19 5.00
118 INT297310 Binding of Cxcl1 and Rbm39 1 0.01 0.98 0.19 5.00
119 INT328310 DBT Positive_regulation of Localization of GH1 1 0.00 0 0.19 5.00
120 INT318298 MECOM Negative_regulation of Binding of CD28 1 0.00 1.08 0.18 5.00
121 INT355504 ANGPT2 Positive_regulation of CYBB 1 0.01 0.81 0.18 5.00
122 INT281307 Binding of Selp and Selplg 1 0.01 0.76 0.17 5.00
123 INT281318 Binding of Selp and Selplg Positive_regulation of Gene_expression of Selplg 1 0.00 0.76 0.17 5.00
124 INT350363 Gatm Negative_regulation of NOS1 1 0.00 0.31 0.17 5.00
125 INT328386 GHS Positive_regulation of Localization of Ghrl 1 0.10 0.88 0.17 5.00
126 INT311226 DPP4 Negative_regulation of GLP1R 1 0.31 0.65 0.16 5.00
127 INT207784 Ap3d1 Regulation of CACNA1S 1 0.05 0.97 0.16 5.00
128 INT311227 INS Negative_regulation of HBA1 1 0.01 0.52 0.16 5.00
129 INT328379 Ghrl Positive_regulation of CRH 1 0.16 1.17 0.16 5.00
130 INT125770 GLP1R Negative_regulation of Localization of GCG 2 0.29 0.65 0.16 5.00
131 INT242400 Binding of Bdkrb2 and Ros1 1 0.02 0.84 0.15 5.00
132 INT344135 Negative_regulation of Binding of Col7a1 and Lhyp 1 0.00 0.5 0.13 5.00
133 INT328374 GHRH Positive_regulation of Ghrl 1 0.13 0.26 0.13 5.00
134 INT297312 Esr1 Positive_regulation of Scap 1 0.00 1.58 0.13 5.00
135 INT258016 AGTR1 Positive_regulation of EGFR 1 0.15 1.24 0.13 5.00
136 INT344134 Binding of Col7a1 and Lhyp 1 0.00 0.5 0.13 5.00
137 INT328384 Ghrl Positive_regulation of ALPL 1 0.01 0.93 0.13 5.00
138 INT207785 Binding of RYR1 and Ap3d1 1 0.06 3.24 0.13 5.00
139 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12 5.00
140 INT328309 GHS Positive_regulation of Localization of GH1 1 0.04 0.99 0.12 5.00
141 INT281301 Stx2 Positive_regulation of Localization of F3 1 0.10 0.19 0.11 5.00
142 INT288616 EPO Positive_regulation of Nos3 1 0.08 0.69 0.11 5.00
143 INT281311 Tlr4 Positive_regulation of Localization of F3 1 0.04 0.19 0.11 5.00
144 INT328313 Binding of CD36 and LDLR 1 0.00 0.63 0.11 5.00
145 INT352497 AGT Positive_regulation of Binding of CRS 1 0.14 0.87 0.11 5.00
146 INT328294 GHS Positive_regulation of Localization of GHRH 1 0.10 0.12 0.11 5.00
147 INT328370 Binding of CD36 and Fabp1 1 0.01 0.64 0.11 5.00
148 INT328364 Binding of GHRH and Ghrl 1 0.09 0.2 0.1 5.00
149 INT328297 GHRH Positive_regulation of Transcription of GH1 1 0.04 0.26 0.1 5.00
150 INT328372 Ghrl Positive_regulation of Transcription of GH1 1 0.04 0.27 0.1 5.00
151 INT281309 Tlr4 Positive_regulation of Gene_expression of F3 1 0.04 0.15 0.09 5.00
152 INT281312 Stx2 Positive_regulation of Gene_expression of F3 1 0.10 0.15 0.09 5.00
153 INT328311 Binding of GH1 and GHS 1 0.02 0.14 0.09 5.00
154 INT273655 Binding of FUT1 and Cxcr4 1 0.07 0.41 0.09 5.00
155 INT328373 Negative_regulation of Ghrl Positive_regulation of Localization of GH1 1 0.05 0.31 0.08 5.00
156 INT297317 Positive_regulation of Mthfd1 Positive_regulation of Gene_expression of Il18 1 0.07 0.79 0.08 5.00
157 INT297309 Positive_regulation of Mthfd1 Positive_regulation of Gene_expression of Ifng 1 0.07 0.79 0.08 5.00
158 INT273649 Binding of Vcam1 and Itga1 1 0.01 0.4 0.08 5.00
159 INT241741 Sdhb Positive_regulation of Transcription of Adora2b 1 0.07 0.28 0.08 5.00
160 INT205119 Binding of HIVEP1 and GREM1 1 0.00 2.24 0.08 5.00
161 INT328302 Gene_expression of GHS Positive_regulation of Gene_expression of GH1 1 0.03 0.17 0.08 5.00
162 INT250174 Binding of Tlr4 and Itprip 1 0.14 0.88 0.08 5.00
163 INT328306 GH1 Positive_regulation of Localization of INS 1 0.01 0.12 0.07 5.00
164 INT328366 GPR39 Regulation of Localization of Ghrl 1 0.11 0.2 0.07 5.00
165 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07 5.00
166 INT328380 AR Negative_regulation of Gene_expression of Ghrl 1 0.01 0.55 0.07 5.00
167 INT311225 GLP1R Positive_regulation of Gene_expression of INS 1 0.49 0.33 0.06 5.00
168 INT273653 Cxcr4 Negative_regulation of Binding of FUT1 1 0.08 0.21 0.06 5.00
169 INT281303 Binding of Stx2 and Tlr4 1 0.11 0.09 0.06 5.00
170 INT328305 GHS Positive_regulation of Localization of INS 1 0.02 0.07 0.05 5.00
171 INT328387 INS Negative_regulation of Gene_expression of Ghrl 1 0.01 0.6 0.05 5.00
172 INT258015 Binding of ANGPT2 and REN 1 0.01 0.59 0.05 5.00
173 INT328371 Ghrl Negative_regulation of INS 1 0.03 0.13 0.05 5.00
174 INT222295 Binding of CPP and Cebpz 1 0.00 0.73 0.05 5.00
175 INT328376 Ghrl Negative_regulation of SST 1 0.03 0.13 0.05 5.00
176 INT328383 Ghrl Negative_regulation of MBOAT4 1 0.26 0 0.05 5.00
177 INT328367 KISS1 Positive_regulation of Localization of Gnrh1 1 0.00 0 0.05 5.00
178 INT328308 CRH Negative_regulation of KISS1 1 0.02 0 0.05 5.00
179 INT328292 KISS1 Positive_regulation of Localization of PLOD1 1 0.00 0 0.05 5.00
180 INT328293 Binding of JAG2 and GHS 1 0.03 0.09 0.05 5.00
181 INT328365 Binding of JAG2 and Ghrl 1 0.03 0.07 0.05 5.00
182 INT258012 ANGPT2 Positive_regulation of Binding of AGTR1 and ANGPT2 1 0.00 0.29 0.04 5.00
183 INT273654 Binding of FUT1 and Sdf2l1 1 0.07 0.19 0.04 5.00
184 INT328303 Gene_expression of GHS Positive_regulation of Gene_expression of GHRH 1 0.09 0.19 0.04 5.00
185 INT258020 Binding of AGTR1 and ANGPT2 1 0.03 0.29 0.04 5.00
186 INT328301 GHRH Positive_regulation of SCG5 1 0.24 0.13 0.04 5.00
187 INT328295 GHRH Positive_regulation of GHS 1 0.10 0.13 0.04 5.00
188 INT273651 Sdf2l1 Positive_regulation of FUT1 1 0.10 0.35 0.04 5.00
189 INT328332 Ghrl Negative_regulation of Abo 1 0.01 0 0.04 5.00
190 INT328312 GHS Positive_regulation of Localization of PRL 1 0.02 0.21 0.03 5.00
191 INT328362 LYPLA1 Regulation of Ghrl 1 0.04 0.07 0.03 5.00
192 INT198595 Binding of CFH and CFHR1 3 0.41 1.36 0.03 5.00
193 INT327451 HTN1 Positive_regulation of Adra1a 1 0.00 1.36 0.03 5.00
194 INT269838 Binding of Hsp90b1 and Tlr2 1 0.26 1.75 0.03 5.00
195 INT328381 Ghrl Positive_regulation of NPY 1 0.06 0.15 0.03 5.00
196 INT328304 POMC Positive_regulation of Localization of CRH 1 0.07 0.22 0.03 5.00
197 INT270116 DMD Regulation of St13 1 0.01 0.09 0 5.00
198 INT264979 Binding of POR and BAG3 1 0.15 0.38 0 5.00
199 INT328298 GHRH Negative_regulation of Localization of GHS 1 0.08 0.84 0 5.00
200 INT328369 Ghrl Negative_regulation of CRH 1 0.16 0.15 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Acute Renal Failure. They are ordered first by their pain relevance and then by number of times they were reported in Acute Renal Failure. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 100.00
2 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38 100.00
3 INT13295 Positive_regulation of Cdkn2a 18 0.68 13.02 5.47 100.00
4 INT78248 Negative_regulation of Cdkn2a 17 0.59 15.15 2.8 100.00
5 INT92138 Binding of CDKN2A 28 0.37 25.64 7.47 100.00
6 INT238494 Regulation of Transcription of CDKN2A 1 0.16 5.62 0.25 100.00
7 INT94772 Gene_expression of Cdkn2a 14 0.75 8.25 2.04 100.00
8 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99 100.00
9 INT177886 Positive_regulation of Gene_expression of Cdkn2a 3 0.67 3.42 0.62 100.00
10 INT147149 Transcription of CDKN2A 8 0.67 6.85 0.15 100.00
11 INT42104 Regulation of Cdkn2a 4 0.44 5.67 1.06 100.00
12 INT66401 Positive_regulation of Renf1 2 0.01 2.21 0.85 100.00
13 INT78471 Regulation of Gene_expression of CDKN2A 13 0.45 12.52 3.28 100.00
14 INT91896 Negative_regulation of Gene_expression of Gtpbp4 2 0.13 1.33 0.58 100.00
15 INT68434 Gene_expression of Gtpbp4 15 0.54 5.5 7.91 100.00
16 INT242011 Localization of Cdkn2a 4 0.73 2.49 0.54 100.00
17 INT115039 Positive_regulation of FMR1 4 0.49 2.26 0.46 100.00
18 INT252658 Negative_regulation of Phosphorylation of ABCB7 1 0.41 2.93 0.45 100.00
19 INT251026 Negative_regulation of Phosphorylation of CDKN2A 5 0.42 5.02 0.62 100.00
20 INT125474 Binding of Renf1 1 0.00 0.47 0.46 100.00
21 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48 100.00
22 INT9298 Positive_regulation of Gtpbp4 64 0.69 12.29 41.97 100.00
23 INT65286 Binding of ARIH1 10 0.48 4.3 0.76 100.00
24 INT187301 Negative_regulation of ARIH1 3 0.32 1.23 0.05 100.00
25 INT4436 Gene_expression of ABCB7 7 0.65 9.26 0.93 100.00
26 INT252660 Positive_regulation of Phosphorylation of ABCB7 1 0.49 1.94 0.3 100.00
27 INT252657 Positive_regulation of Phosphorylation of CDKN2A 2 0.45 3.09 0.42 100.00
28 INT273604 Regulation of Negative_regulation of Cdkn2a 1 0.12 0.68 0.09 100.00
29 INT144429 Positive_regulation of Cdkn2a 7 0.58 4.05 0.78 100.00
30 INT252661 Positive_regulation of Gene_expression of ABCB7 2 0.49 1.55 0.31 100.00
31 INT184624 Localization of CDKN2A 8 0.74 7.87 0.25 100.00
32 INT155590 Gene_expression of ARIH1 8 0.58 10.76 0.24 100.00
33 INT252659 Phosphorylation of ABCB7 1 0.79 0.97 0.15 100.00
34 INT184623 Positive_regulation of Localization of CDKN2A 1 0.04 0.86 0 100.00
35 INT135720 Gene_expression of War 7 0.34 3.99 0.28 99.98
36 INT275876 Binding of Chkb 1 0.04 0.54 0.46 99.98
37 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 99.96
38 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 99.96
39 INT9552 Positive_regulation of TNNI3 209 0.70 128.67 19.15 99.96
40 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56 99.92
41 INT251025 Phosphorylation of CDKN2A 4 0.61 3.19 0.32 99.92
42 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33 99.90
43 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6 99.88
44 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 99.88
45 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 99.88
46 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 99.88
47 INT214 Localization of AVP 370 0.81 208.51 91.09 99.84
48 INT6129 Positive_regulation of Localization of AVP 63 0.70 30.44 16.64 99.84
49 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 99.84
50 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 99.82
51 INT18526 Positive_regulation of Aap 19 0.56 12.28 14.57 99.80
52 INT171772 Binding of CPB1 13 0.32 9.92 0.75 99.80
53 INT545 Binding of GC 15 0.45 10.74 3.47 99.76
54 INT80036 Positive_regulation of FAS 42 0.67 42.22 9.4 99.72
55 INT173914 Regulation of Gene_expression of LRP2 3 0.60 6.49 0.78 99.72
56 INT238505 Regulation of Gene_expression of NPHS1 1 0.29 2.93 0.06 99.72
57 INT238503 Positive_regulation of Regulation of FAS 1 0.41 4.39 0.18 99.72
58 INT74293 Positive_regulation of BAK1 13 0.60 14.13 2.73 99.72
59 INT73595 Positive_regulation of BAX 61 0.61 56.97 7.82 99.72
60 INT242067 Positive_regulation of Transcription of Vhl-ps1 1 0.09 0.99 0.04 99.72
61 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 99.68
62 INT9126 Negative_regulation of Xdh 20 0.58 8.58 3.28 99.68
63 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 99.64
64 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 99.64
65 INT238493 Positive_regulation of Gene_expression of TJP1 1 0.16 2.08 0.03 99.62
66 INT111603 Positive_regulation of Gene_expression of CDH1 14 0.49 11.17 1.72 99.62
67 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48 99.62
68 INT9490 Regulation of Mme 44 0.56 6.69 19.21 99.60
69 INT11367 Localization of MB 9 0.78 9.34 1.24 99.60
70 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 99.58
71 INT241736 Negative_regulation of Rapgef5 2 0.57 1 0.04 99.54
72 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 99.48
73 INT98132 Regulation of FAS 16 0.42 20.57 2.06 99.44
74 INT84686 Regulation of BAX 26 0.49 28.54 4.13 99.44
75 INT62800 Regulation of BAK1 7 0.41 10.12 1.47 99.44
76 INT238495 Negative_regulation of Gene_expression of TJP1 5 0.18 9.51 1.05 99.42
77 INT139237 Negative_regulation of Gene_expression of CDH1 23 0.57 24.31 1.28 99.42
78 INT50 Negative_regulation of Localization of Ren 87 0.59 14.94 30.22 99.40
79 INT238496 Negative_regulation of Negative_regulation of LRP2 1 0.42 1.84 0.07 99.36
80 INT126583 Positive_regulation of PARP1 50 0.68 41.44 7.78 99.32
81 INT238489 Negative_regulation of Gene_expression of LRP2 1 0.57 2.74 0.14 99.28
82 INT173916 Regulation of LRP2 6 0.44 7.96 1.14 99.26
83 INT173912 Negative_regulation of LRP2 5 0.57 6.22 0.42 99.26
84 INT152771 Gene_expression of TJP1 19 0.75 14.95 1.98 99.22
85 INT46 Localization of Ren 233 0.81 46.15 62.44 99.22
86 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 99.22
87 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.22
88 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.22
89 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 99.22
90 INT59167 Binding of CSRP1 7 0.35 7.33 0.55 99.20
91 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 99.14
92 INT660 Negative_regulation of REN 194 0.59 82.06 29.46 99.10
93 INT69947 Negative_regulation of MTAP 5 0.40 2.63 0.48 99.08
94 INT238497 Positive_regulation of Regulation of BAX 1 0.22 1.5 0.03 99.06
95 INT173910 Gene_expression of LRP2 24 0.75 19.99 4.09 99.04
96 INT654 Localization of REN 250 0.81 75.12 47.86 99.04
97 INT205654 Gene_expression of FUS 9 0.32 11.53 0.16 99.04
98 INT123877 Negative_regulation of ABL1 40 0.57 27.94 1.17 99.02
99 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 99.00
100 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 99.00
101 INT70744 Regulation of CFH 12 0.41 7.38 0.8 98.98
102 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 98.96
103 INT127137 Gene_expression of TECR 4 0.30 2.08 2.74 98.94
104 INT136850 Positive_regulation of Arg1 10 0.50 6.96 2.47 98.92
105 INT73743 Regulation of TECR 2 0.24 6.27 0.06 98.90
106 INT5489 Localization of CA2 172 0.80 39.46 33.56 98.84
107 INT99348 Negative_regulation of PARP1 38 0.58 30.96 3.36 98.82
108 INT238509 Gene_expression of GTF2E2 1 0.00 1.5 0 98.78
109 INT117662 Gene_expression of ABL1 21 0.69 18.76 0.39 98.78
110 INT168502 Positive_regulation of FUS 3 0.39 9.22 0.59 98.76
111 INT238508 Regulation of Regulation of BAX 1 0.21 1.5 0.03 98.76
112 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 98.72
113 INT38362 Positive_regulation of Wbc1 19 0.06 13.24 2.95 98.72
114 INT48896 Positive_regulation of Gene_expression of Il10 73 0.70 43.14 35.5 98.72
115 INT4210 Gene_expression of MB 24 0.78 11.74 2.32 98.68
116 INT158 Localization of Prl 2431 0.81 378.96 952.2 98.64
117 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 98.64
118 INT242068 Transcription of Vhl-ps1 1 0.12 0.98 0.04 98.64
119 INT2890 Positive_regulation of MB 39 0.70 29.58 6.01 98.60
120 INT84037 Negative_regulation of Regulation of Mme 1 0.37 0.64 0.26 98.60
121 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18 98.58
122 INT99505 Gene_expression of Bcl2l1 42 0.77 33.12 10.15 98.52
123 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 98.52
124 INT44784 Gene_expression of NPHS1 8 0.64 9.75 1.74 98.48
125 INT46522 Positive_regulation of Positive_regulation of Phkg1 1 0.01 0.76 0.1 98.46
126 INT22046 Negative_regulation of IRF6 52 0.43 25.69 14.13 98.34
127 INT204277 Positive_regulation of Cytl1 3 0.67 2.56 1.64 98.34
128 INT331162 Negative_regulation of Gene_expression of AMIGO2 1 0.14 3.28 0.14 98.32
129 INT39348 Positive_regulation of Phkg1 2 0.68 0.76 0.2 98.28
130 INT1973 Positive_regulation of NAGLU 36 0.65 14.78 7 98.24
131 INT11823 Positive_regulation of GGT1 53 0.67 45.84 7.55 98.24
132 INT673 Positive_regulation of B2m 24 0.68 24.24 4.82 98.24
133 INT145457 Positive_regulation of Clec7a 2 0.04 0.17 0.34 98.24
134 INT10060 Negative_regulation of MB 7 0.42 2.51 0.22 98.20
135 INT90097 Localization of PTGS2 15 0.69 6.14 6.63 98.20
136 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 98.16
137 INT6196 Regulation of Nppa 83 0.62 30.31 30.18 98.16
138 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07 98.14
139 INT84685 Regulation of BCL2 67 0.60 72.96 6.65 98.14
140 INT10872 Regulation of Dob2 5 0.20 2.06 0.25 98.14
141 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 98.12
142 INT14111 Positive_regulation of Cyp2c22 41 0.67 7.24 17.88 98.12
143 INT252656 Positive_regulation of Binding of F3 1 0.07 1.89 0.29 98.00
144 INT174271 Binding of F3 6 0.15 6.85 0.53 98.00
145 INT163928 Regulation of Fabp1 3 0.34 2.56 0.72 97.96
146 INT238492 Regulation of MRC2 1 0.03 1.87 0.07 97.92
147 INT238486 Negative_regulation of MRC2 1 0.03 1.87 0.07 97.92
148 INT121126 Positive_regulation of RNF34 9 0.04 6.83 2.05 97.88
149 INT161882 Negative_regulation of Gene_expression of NPHS1 2 0.41 6.54 0.95 97.84
150 INT136851 Regulation of Arg1 7 0.38 3.05 0.37 97.80
151 INT178221 Negative_regulation of Gene_expression of HBG1 3 0.33 2.43 0.13 97.76
152 INT8773 Gene_expression of HBG1 58 0.76 37.6 4.59 97.76
153 INT2792 Gene_expression of Mb 91 0.76 41.56 10.25 97.60
154 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 97.56
155 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97 97.52
156 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 97.48
157 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 97.48
158 INT28872 Positive_regulation of CSRP1 49 0.70 47.23 11.7 97.36
159 INT281286 Binding of Stx2 1 0.39 2.02 0.55 97.32
160 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 97.24
161 INT84598 Regulation of Aqp2 13 0.45 4.28 0.86 97.20
162 INT125743 Negative_regulation of Nsf 5 0.58 3.07 1.71 97.12
163 INT6490 Negative_regulation of ADCY1 145 0.58 26.25 70.96 97.08
164 INT281290 Positive_regulation of Hus1 1 0.01 0.95 0 97.08
165 INT2393 Positive_regulation of Mb 174 0.69 93.59 26.79 96.96
166 INT7678 Localization of Alb 142 0.81 80.93 22.49 96.96
167 INT2395 Binding of MB 18 0.36 7.53 0.68 96.96
168 INT179222 Gene_expression of AMIGO2 7 0.66 7.68 1.77 96.80
169 INT238500 Positive_regulation of Gene_expression of MRC2 1 0.03 2.83 0.07 96.76
170 INT126585 Positive_regulation of Positive_regulation of PARP1 3 0.55 2.84 0.56 96.76
171 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 96.72
172 INT546 Binding of ALB 311 0.48 85.98 60.14 96.64
173 INT104547 Negative_regulation of Il18 24 0.59 17.89 6.01 96.56
174 INT27574 Binding of ZFPL1 1 0.07 1.01 0.31 96.36
175 INT10207 Gene_expression of PADI4 22 0.75 23.49 1.74 96.20
176 INT192809 Negative_regulation of SSRP1 2 0.04 4.06 0.33 96.08
177 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 95.92
178 INT80034 Positive_regulation of Gene_expression of FAS 32 0.67 30.34 8.51 95.88
179 INT130773 Regulation of Gene_expression of FAS 5 0.37 6.87 1.32 95.88
180 INT5411 Positive_regulation of G6pd 20 0.70 4.74 5.11 95.84
181 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 95.72
182 INT138843 Binding of CC2D1A 19 0.33 33.06 1.25 95.72
183 INT116459 Negative_regulation of VWF 8 0.58 5.66 0.89 95.68
184 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 95.52
185 INT11346 Binding of Mtx1 39 0.41 24.88 21.21 95.48
186 INT35699 Binding of Umod 3 0.41 2.3 0.46 95.44
187 INT653 Negative_regulation of Localization of REN 67 0.59 20.33 16.7 95.40
188 INT5409 Negative_regulation of G6pd 33 0.57 29.21 7.64 95.40
189 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71 95.40
190 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01 95.28
191 INT154456 Negative_regulation of dds 5 0.37 5.66 0.52 95.04
192 INT154455 Gene_expression of dds 4 0.58 3.84 0.46 95.04
193 INT8111 Localization of EPO 32 0.81 19.53 2.54 94.72
194 INT288608 Localization of Epor 1 0.73 3.34 0.37 94.72
195 INT288615 Localization of CSF2RB 1 0.26 3.34 0.35 94.72
196 INT130014 Positive_regulation of BMP2 11 0.66 5.34 1.42 94.64
197 INT1934 Positive_regulation of Cys1 68 0.68 60.56 10.47 94.40
198 INT46134 Positive_regulation of Gene_expression of Cys1 4 0.50 11.52 0.61 94.40
199 INT238501 Negative_regulation of Gene_expression of MRC2 1 0.03 2.71 0.07 94.24
200 INT4435 Gene_expression of PIK3C2A 20 0.77 14.43 2.48 94.24
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