D:Adenoid Cystic Carcinoma

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Disease Term
Synonyms Adenoid Cystic Carcinomas, Carcinomas Adenoid Cystic, Cylindroma, Cylindromas, Cystic Carcinoma Adenoid, Cystic Carcinomas Adenoid
Documents 163
Hot Single Events 37
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Adenoid Cystic Carcinoma. They are ordered first by their relevance to Adenoid Cystic Carcinoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT292882 Binding of S100A12 and TP63 1 0.06 0.51 0 56.36
2 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19 9.64
3 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
4 INT134212 CRH Regulation of Localization of POMC 1 0.47 2.89 2.9 5.00
5 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69 5.00
6 INT232917 Binding of KRT8 and KRT19 2 0.16 1.04 0.08 5.00
7 INT232914 Binding of KRT2 and KRT7 1 0.15 0.63 0.05 5.00
8 INT232916 Binding of KRT2 and KRT19 1 0.21 0.62 0.05 5.00
9 INT232907 Binding of KRT7 and KRT8 1 0.09 0.63 0.05 5.00
10 INT232918 Binding of KRT2 and KRT8 1 0.17 0.59 0 5.00
11 INT241500 Binding of Kit and Kitl 1 0.08 0.92 0 5.00
12 INT232912 Binding of KRT4 and KRT13 1 0.07 0.06 0 5.00
13 INT232910 Binding of KRT12 and KRT76 1 0.39 0.2 0 5.00
14 INT232911 Binding of KRT18 and PLAT 1 0.05 1.3 0 5.00
15 INT256632 Binding of PTCH1 and Jkamp 1 0.00 2.32 0 5.00
16 INT335526 SPHK1 Regulation of Gene_expression of SGCB 1 0.27 0.86 0 5.00
17 INT232915 Binding of KRT8 and PLAT 1 0.04 1.3 0 5.00
18 INT335525 Binding of SGCB and SPHK1 1 0.22 1.61 0 5.00
19 INT232909 Binding of KRT1 and KRT9 1 0.16 0.5 0 5.00
20 INT242102 Nkx2-1 Regulation of Gene_expression of Ttf1 1 0.00 1.55 0 5.00
21 INT305632 Binding of BCL6 and MME 1 0.00 1.37 0 5.00
22 INT232913 Binding of KRT3 and NBPF14 1 0.01 0.21 0 5.00
23 INT232908 Binding of KRT19 and PLAT 1 0.05 1.31 0 5.00
24 INT232906 Binding of KRT1 and KRT10 1 0.18 0.51 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Adenoid Cystic Carcinoma. They are ordered first by their pain relevance and then by number of times they were reported in Adenoid Cystic Carcinoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT8571 Gene_expression of B3GAT1 54 0.75 36.85 15.98 100.00
2 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 99.80
3 INT119102 Gene_expression of PDGFRA 13 0.75 11.99 0.81 99.80
4 INT129783 Positive_regulation of Gene_expression of KIT 16 0.50 18.12 0.58 99.72
5 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 99.72
6 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 99.40
7 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 98.68
8 INT17110 Gene_expression of PSMD1 60 0.65 19.57 4.69 98.32
9 INT143850 Gene_expression of S100a1 19 0.73 9.52 1.54 98.08
10 INT214 Localization of AVP 370 0.81 208.51 91.09 98.04
11 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 97.84
12 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23 97.80
13 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 97.68
14 INT75501 Gene_expression of CCND1 90 0.76 60.86 5.93 97.68
15 INT75498 Positive_regulation of Gene_expression of CCND1 21 0.68 19.4 0.51 97.68
16 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49 97.68
17 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 97.68
18 INT163832 Negative_regulation of Gene_expression of EGFR 50 0.59 39.71 3.45 97.68
19 INT273676 Gene_expression of STATH 13 0.08 2.15 0 97.52
20 INT273678 Gene_expression of VWA5A 1 0.01 0.16 0 97.52
21 INT151450 Positive_regulation of Gene_expression of Kit 23 0.69 13.11 1.43 97.32
22 INT232977 Gene_expression of KRT77 1 0.75 3.41 0 96.80
23 INT273679 Regulation of VWA5A 1 0.01 0.17 0 96.08
24 INT273677 Gene_expression of ACACB 15 0.67 9.36 0 96.04
25 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 96.04
26 INT88278 Binding of Kit 33 0.37 24.45 4.13 93.64
27 INT70265 Regulation of MRI1 42 0.39 30.95 14.18 92.52
28 INT146179 Gene_expression of KRT6A 23 0.75 9.39 0.52 91.96
29 INT91890 Positive_regulation of Kit 36 0.50 25.44 3.06 91.76
30 INT86639 Gene_expression of KRT16 19 0.68 12.44 7.79 91.68
31 INT142184 Regulation of TXK 10 0.11 8.25 0.59 90.80
32 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 90.76
33 INT280594 Gene_expression of SPHK1 2 0.78 71.47 0.19 88.16
34 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 88.00
35 INT335535 Positive_regulation of SPHK1 1 0.69 12.71 0 87.76
36 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 85.64
37 INT335530 Positive_regulation of Gene_expression of SPHK1 1 0.69 21.31 0 84.48
38 INT117662 Gene_expression of ABL1 21 0.69 18.76 0.39 79.20
39 INT335539 Regulation of Gene_expression of SPHK1 1 0.62 4.55 0 79.04
40 INT11203 Gene_expression of BCR 30 0.75 33.49 1.22 78.88
41 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 75.44
42 INT214457 Transcription of KRT7 1 0.19 1.49 0 74.64
43 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19 74.36
44 INT36798 Gene_expression of Mki67 178 0.77 132 8.24 73.24
45 INT273681 Positive_regulation of Gene_expression of STATH 1 0.04 0.4 0 72.44
46 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19 71.84
47 INT125627 Gene_expression of TTF1 11 0.78 12.68 0.78 71.84
48 INT156595 Gene_expression of CDX2 10 0.69 7.8 0.25 71.84
49 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 69.48
50 INT280589 Localization of SPHK1 2 0.75 2.61 0.13 69.40
51 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 67.24
52 INT227013 Positive_regulation of KRT17 2 0.27 2.4 0 66.96
53 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34 66.80
54 INT5136 Negative_regulation of PDYN 71 0.59 11.22 51.14 66.80
55 INT1154 Negative_regulation of CCK 24 0.59 9.3 15.32 66.80
56 INT14681 Negative_regulation of GCG 31 0.57 13.55 4.98 66.80
57 INT85084 Gene_expression of KRT19 66 0.73 42.56 1.82 63.56
58 INT227017 Gene_expression of KRT17 2 0.45 14.84 0.41 63.56
59 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 62.76
60 INT111477 Gene_expression of KRT7 90 0.74 86.76 4.07 60.68
61 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 58.08
62 INT136180 Binding of MTOR 9 0.35 5.01 0.38 57.84
63 INT11154 Binding of EGFR 149 0.48 96.23 6.29 56.04
64 INT233008 Gene_expression of KRT75 1 0.56 1.07 0.11 55.08
65 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55 54.84
66 INT136182 Negative_regulation of PDGFRA 3 0.43 2.43 0.08 53.36
67 INT95116 Negative_regulation of PDGFA 24 0.57 19.56 1.29 51.92
68 INT24443 Gene_expression of PSMD2 20 0.54 7.29 2.77 50.00
69 INT160084 Gene_expression of L1CAM 15 0.78 10.92 1.42 50.00
70 INT36451 Gene_expression of G6PD 26 0.75 7.2 1.09 50.00
71 INT273675 Binding of ACACB 7 0.42 8.69 0.09 50.00
72 INT273680 Regulation of Gene_expression of STATH 1 0.04 0 0 50.00
73 INT109327 Negative_regulation of KIT 42 0.57 43.2 2.15 48.72
74 INT123877 Negative_regulation of ABL1 40 0.57 27.94 1.17 48.32
75 INT335531 Phosphorylation of SPHK1 1 0.81 1 0 47.92
76 INT136181 Negative_regulation of BCR 5 0.42 2.94 0 47.60
77 INT177586 Positive_regulation of Gene_expression of MRI1 9 0.33 4.97 2.91 46.84
78 INT258231 Phosphorylation of S1PR1 2 0.45 0.95 0 46.84
79 INT101068 Negative_regulation of CDCP1 27 0.03 17.67 3.45 46.40
80 INT129312 Gene_expression of SGCB 24 0.76 18.25 3.75 42.12
81 INT335536 Positive_regulation of Gene_expression of SGCB 1 0.26 1.46 0 42.12
82 INT205973 Binding of SHH 3 0.35 1.03 0.07 41.16
83 INT213515 Binding of Shh 8 0.37 1.92 0.08 40.52
84 INT335534 Regulation of Positive_regulation of SGCB 1 0.23 0.86 0 39.20
85 INT142416 Binding of Ptch1 6 0.34 4.92 0.74 38.44
86 INT232944 Transcription of KRT75 1 0.43 0.59 0.18 38.24
87 INT57785 Positive_regulation of SGCB 25 0.69 5.01 1.49 38.04
88 INT280593 Negative_regulation of Gene_expression of SPHK1 2 0.43 3.92 0.19 37.00
89 INT14682 Regulation of B3GAT1 9 0.54 3.9 4.06 36.08
90 INT11920 Regulation of ENO2 18 0.55 11.51 2.89 34.80
91 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 33.96
92 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 33.60
93 INT167085 Negative_regulation of ERBB2 67 0.57 44.6 1.48 33.20
94 INT335533 Negative_regulation of SPHK1 1 0.59 2.38 0 31.52
95 INT15610 Localization of GOPC 223 0.65 68.26 28.7 24.88
96 INT233004 Localization of KRT17 1 0.36 0.19 0 22.36
97 INT186056 Binding of MKI67 6 0.48 4.44 0.1 21.96
98 INT292884 Positive_regulation of Binding of MKI67 1 0.06 0.52 0 21.96
99 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77 18.52
100 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16 18.52
101 INT135299 Binding of PTCH1 10 0.48 12.16 0.84 15.68
102 INT280581 Regulation of SPHK1 2 0.45 1.33 0.13 12.72
103 INT339223 Binding of Ptv1 1 0.06 1.41 0.17 9.20
104 INT335538 Positive_regulation of Transcription of SGCB 1 0.24 0.74 0 8.96
105 INT335529 Transcription of SPHK1 1 0.53 0.74 0 8.96
106 INT335540 Transcription of SGCB 1 0.28 0.74 0 8.96
107 INT127064 Gene_expression of KRT76 7 0.75 1.71 1.1 6.48
108 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
109 INT443 Localization of POMC 1020 0.81 284.52 443.17 5.00
110 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
111 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
112 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
113 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 5.00
114 INT5453 Regulation of Localization of POMC 114 0.62 20.56 56.34 5.00
115 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 5.00
116 INT1726 Positive_regulation of Kitl 65 0.70 38.81 44.85 5.00
117 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
118 INT5454 Localization of CRH 124 0.79 79.18 41.53 5.00
119 INT16323 Gene_expression of pr 62 0.66 36.14 38.26 5.00
120 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 5.00
121 INT7082 Gene_expression of CRH 180 0.78 64.66 31.74 5.00
122 INT16428 Positive_regulation of Gtf3a 135 0.20 106.44 26.67 5.00
123 INT74423 Localization of IL10 91 0.80 61.6 22.95 5.00
124 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 5.00
125 INT3400 Positive_regulation of pr 57 0.68 36.9 16.24 5.00
126 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 5.00
127 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99 5.00
128 INT173505 Localization of Hand2 63 0.57 45.32 13.66 5.00
129 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 5.00
130 INT69158 Localization of IL4 48 0.71 31.3 11.98 5.00
131 INT14867 Gene_expression of Igh-6 47 0.67 30.05 11.75 5.00
132 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 5.00
133 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 5.00
134 INT62919 Regulation of Gnas 22 0.43 5.61 9.55 5.00
135 INT22383 Binding of IL2 59 0.48 39.06 8.56 5.00
136 INT61628 Negative_regulation of Gene_expression of IL4 31 0.55 20.96 8.18 5.00
137 INT1150 Gene_expression of ecs 42 0.59 29.38 7.73 5.00
138 INT103925 Negative_regulation of Positive_regulation of Akt1 32 0.58 15.19 7.39 5.00
139 INT132822 Localization of IL13 26 0.67 22.85 6.66 5.00
140 INT91721 Binding of IL18 21 0.48 21.17 6.56 5.00
141 INT64052 Positive_regulation of FGFR1 26 0.52 28.47 6.36 5.00
142 INT11258 Gene_expression of Gnas 58 0.58 21.6 6.33 5.00
143 INT38672 Binding of KRT20 69 0.39 48.01 6.31 5.00
144 INT39416 Gene_expression of Cd79a 81 0.64 45.17 6.08 5.00
145 INT132573 Negative_regulation of Gene_expression of TH1L 16 0.42 11.52 5.76 5.00
146 INT57502 Positive_regulation of Gene_expression of CRH 30 0.70 23.37 5.7 5.00
147 INT38671 Positive_regulation of KRT20 62 0.53 40.17 5.6 5.00
148 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56 5.00
149 INT38670 Positive_regulation of Gene_expression of KRT20 68 0.69 23.25 5.55 5.00
150 INT28088 Binding of Alb 34 0.47 11.06 5.48 5.00
151 INT60585 Regulation of TP53 59 0.59 54.55 5.21 5.00
152 INT94466 Regulation of Gene_expression of Hand2 14 0.28 7.97 4.46 5.00
153 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12 5.00
154 INT30014 Positive_regulation of HPSE 22 0.70 20.91 4.09 5.00
155 INT23317 Gene_expression of Spn 20 0.48 14.51 4.01 5.00
156 INT35175 Localization of IL18 18 0.80 12.96 3.83 5.00
157 INT124185 Negative_regulation of Kit 57 0.59 35.43 3.61 5.00
158 INT69155 Positive_regulation of Localization of IL4 13 0.40 10.18 3.56 5.00
159 INT14201 Localization of Igh-6 9 0.81 3.29 3.36 5.00
160 INT95652 Gene_expression of Krt20 54 0.61 53.69 3.31 5.00
161 INT91173 Gene_expression of Pdgfrb 33 0.65 32.55 3.09 5.00
162 INT86640 Positive_regulation of Gene_expression of KRT16 5 0.61 2.5 2.99 5.00
163 INT38673 Negative_regulation of KRT20 38 0.42 22.49 2.77 5.00
164 INT96338 Gene_expression of HPSE 17 0.75 18.71 2.73 5.00
165 INT221269 Binding of BRCA1 14 0.40 31.77 2.7 5.00
166 INT142908 Localization of FGFR1 18 0.38 11.46 2.57 5.00
167 INT40315 Gene_expression of Abcc1 10 0.76 5.66 2.53 5.00
168 INT137908 Phosphorylation of Pdgfrb 14 0.81 8.44 2.45 5.00
169 INT35027 Positive_regulation of Gene_expression of Igh-6 6 0.02 4.26 2.24 5.00
170 INT37394 Localization of ecs 9 0.34 6.41 2.11 5.00
171 INT137906 Positive_regulation of Phosphorylation of Pdgfrb 6 0.50 2.55 1.94 5.00
172 INT111143 Regulation of Gene_expression of KRT20 22 0.26 5.65 1.93 5.00
173 INT144020 Positive_regulation of Pdgfrb 30 0.69 24.8 1.92 5.00
174 INT140175 Regulation of Kit 23 0.62 8.59 1.79 5.00
175 INT71788 Gene_expression of MAP3K1 13 0.70 4.9 1.66 5.00
176 INT233010 Gene_expression of PERP 5 0.26 6.04 1.66 5.00
177 INT119520 Gene_expression of TXK 19 0.19 17.54 1.45 5.00
178 INT112109 Gene_expression of FIGF 13 0.31 8.31 1.44 5.00
179 INT139077 Negative_regulation of Ptch1 5 0.56 5.22 1.29 5.00
180 INT137382 Negative_regulation of Gene_expression of KRT20 22 0.58 12.29 1.29 5.00
181 INT206696 Regulation of Gene_expression of TH1L 5 0.20 4.44 1.26 5.00
182 INT144019 Negative_regulation of Pdgfrb 21 0.58 14.93 1.26 5.00
183 INT90670 Positive_regulation of KRT1 10 0.44 6.25 1.16 5.00
184 INT93168 Gene_expression of Ttf1 24 0.63 17.18 1.14 5.00
185 INT51264 Positive_regulation of TXK 21 0.54 10.69 1.1 5.00
186 INT191018 Positive_regulation of Gene_expression of Cd79a 12 0.26 8.01 1.05 5.00
187 INT148121 Gene_expression of KRT8 35 0.65 29.07 1.05 5.00
188 INT5006 Transcription of KRT20 9 0.46 7.11 1.03 5.00
189 INT160235 Positive_regulation of Gene_expression of FIGF 4 0.20 5.53 1 5.00
190 INT83479 Gene_expression of KRT18 30 0.65 27.29 1 5.00
191 INT11160 Regulation of Gene_expression of EGFR 27 0.62 22.05 0.96 5.00
192 INT206467 Gene_expression of IARS 11 0.33 6.65 0.93 5.00
193 INT199563 Negative_regulation of Abl1 38 0.46 21.5 0.87 5.00
194 INT71784 Positive_regulation of Gene_expression of MAP3K1 4 0.34 4.8 0.82 5.00
195 INT241499 Binding of Abl1 23 0.47 8.86 0.75 5.00
196 INT127633 Localization of KRT18 5 0.52 5.93 0.75 5.00
197 INT160736 Negative_regulation of KRT7 9 0.41 10.08 0.68 5.00
198 INT153257 Regulation of Ptch1 6 0.36 5.92 0.67 5.00
199 INT206139 Phosphorylation of KRT20 8 0.48 9.1 0.66 5.00
200 INT117437 Protein_catabolism of KRT18 3 0.46 4.64 0.61 5.00
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