D:Advanced Or Metastatic Breast Cancer

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Disease Term
Synonyms Advanced Breast Cancer, Advanced Breast Cancers, Metastatic Breast Cancer, Metastatic Breast Cancers
Documents 799
Hot Single Events 200
Hot Interactions 36

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Advanced Or Metastatic Breast Cancer. They are ordered first by their relevance to Advanced Or Metastatic Breast Cancer and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT341847 ERBB2 Positive_regulation of Gene_expression of ESYT1 1 0.02 1.42 0.03 100.00
2 INT251780 RRAD Negative_regulation of MTOR 1 0.00 0.62 0 99.24
3 INT68691 Positive_regulation of Binding of CSF2 and IL3 1 0.49 2.63 0.48 98.40
4 INT251776 Negative_regulation of TXK Negative_regulation of ERBB4 1 0.04 1.07 0.06 97.96
5 INT251774 Negative_regulation of TXK Negative_regulation of EGFR 1 0.07 1.06 0.06 97.96
6 INT11684 Binding of CSF2 and IL3 6 0.36 3.3 0.72 97.48
7 INT341856 Binding of EGFR and IgG1 1 0.27 1.12 0 96.52
8 INT3178 TSHR Positive_regulation of Prl 1 0.00 0.58 0.31 96.40
9 INT176326 IL2 Positive_regulation of Gene_expression of MUC1 1 0.08 0.71 0.04 96.24
10 INT223581 TXK Negative_regulation of DBP 1 0.00 0.47 0 95.52
11 INT158615 Binding of Serpine1 and Plaur 1 0.04 0.38 0.1 95.08
12 INT158612 Binding of Vtn and Plaur 1 0.00 0.43 0.1 93.56
13 INT224308 INSRR Regulation of VEGFA 1 0.00 1.42 0.16 92.24
14 INT256418 PPARA Positive_regulation of NR1H4 1 0.01 1.17 0.04 91.24
15 INT351085 Binding of EGFR and Positive_regulation of Phosphorylation of TXK 1 0.04 0.35 0 91.20
16 INT1390 Trh Positive_regulation of Prl 14 0.67 4.42 4.39 90.88
17 INT251777 Negative_regulation of TXK Positive_regulation of PDGFA 1 0.04 1 0.08 86.80
18 INT251773 TXK Positive_regulation of PDGFA 1 0.04 1 0.08 86.80
19 INT251778 Negative_regulation of TXK Positive_regulation of KDR 1 0.03 0.99 0.05 86.80
20 INT251779 TXK Positive_regulation of KDR 1 0.03 0.99 0.05 86.80
21 INT213903 Binding of EGFR and ERBB2 10 0.37 5.03 0.04 86.68
22 INT223577 TXK Negative_regulation of EGFR 1 0.08 0.18 0 85.92
23 INT223583 TXK Negative_regulation of ERBB2 1 0.07 0.18 0 85.92
24 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29 85.20
25 INT71904 Binding of ESR1 and PGR 6 0.34 3.79 0.27 85.20
26 INT341827 Binding of ESR1 and TNC 1 0.14 0.63 0.11 85.20
27 INT222300 Binding of ERBB2 and PGR 2 0.34 1.89 0.17 85.04
28 INT341825 Binding of TNC and PGR 1 0.14 0.63 0.09 85.04
29 INT341826 Binding of ERBB2 and TNC 1 0.18 0.63 0.09 84.72
30 INT351090 Phosphorylation of TXK Positive_regulation of EGFR 1 0.04 0.33 0 82.72
31 INT158614 Negative_regulation of Binding of Serpine1 and Vtn 1 0.03 0.48 0.09 82.16
32 INT287268 Binding of ERBB2 and ERBB3 5 0.16 2.74 0 81.88
33 INT158613 Binding of Serpine1 and Vtn 1 0.02 0.95 0.16 81.68
34 INT337627 Binding of CLEC3B and Positive_regulation of Positive_regulation of PLG 1 0.52 1.22 0 81.20
35 INT79163 Binding of PLG and CLEC3B 2 0.29 3.18 0 81.20
36 INT79164 CLEC3B Positive_regulation of Positive_regulation of PLG 2 0.78 2.67 0 80.24
37 INT251775 AGK Negative_regulation of INSRR 1 0.00 1.1 0.07 77.84
38 INT232559 Map3k1 Positive_regulation of Esr1 1 0.19 0.26 0.09 77.04
39 INT232557 Erbb2 Positive_regulation of Esr1 1 0.23 0.26 0.09 77.04
40 INT250669 Binding of TP53 and ST8SIA4 1 0.02 0.51 0 75.68
41 INT287269 Binding of ERBB3 and PIK3CG 1 0.11 0.74 0 75.12
42 INT343546 Negative_regulation of ROCK1 Negative_regulation of Gene_expression of PTHLH 1 0.16 3.28 0.03 75.00
43 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41 75.00
44 INT89475 TGFB1 Positive_regulation of Gene_expression of PTHLH 3 0.61 3.64 0.21 75.00
45 INT84741 Binding of PBK and Cea 1 0.25 0.43 0 75.00
46 INT84739 Binding of Ighg1 and Cea 1 0.31 0.43 0 75.00
47 INT250662 FNTA Positive_regulation of Positive_regulation of RASGRP1 1 0.00 0.79 0.07 74.48
48 INT123462 Binding of TNF and Tnfrsf11b 3 0.21 3.52 0.24 73.56
49 INT123461 Binding of TNFSF10 and Tnfrsf11b 1 0.00 1.34 0.08 73.56
50 INT41006 GNRH1 Negative_regulation of Localization of CGA 1 0.03 0.87 0.3 71.76
51 INT222299 Binding of CYP19A1 and AIS 2 0.25 1.65 0.31 71.52
52 INT181765 WISP3 Regulation of Gene_expression of RHOC 1 0.49 1.46 0.21 70.80
53 INT187640 Binding of EGFR and KLF1 3 0.01 2.54 0 69.60
54 INT250664 PIK3CB Positive_regulation of AKT1 1 0.09 0.62 0 69.36
55 INT294088 Binding of ERBB2 and ERBB4 2 0.13 0.88 0 69.00
56 INT211883 Binding of RET and CDCP1 1 0.00 2.12 0 68.40
57 INT280270 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.08 1.81 0.19 67.72
58 INT280268 Tgfb1 Positive_regulation of Gene_expression of Vegfa 1 0.06 1.81 0.19 67.72
59 INT280261 Tgfb1 Positive_regulation of Gene_expression of Cxcr1 1 0.05 1.81 0.19 67.72
60 INT280274 Tgfb1 Positive_regulation of Gene_expression of VEGFA 1 0.02 2.58 0.19 67.72
61 INT280266 Tgfb1 Positive_regulation of Vegfa 1 0.09 1.8 0.19 67.52
62 INT211882 Binding of KIT and CDCP1 1 0.00 2.1 0 67.12
63 INT266925 Regulation of Binding of EGFR and ERBB2 1 0.26 0.5 0 66.32
64 INT280275 Tgfb1 Positive_regulation of VEGFA 1 0.02 2.46 0.19 66.08
65 INT280260 Tgfb1 Positive_regulation of Cxcr1 1 0.07 1.78 0.19 65.52
66 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3 65.36
67 INT206705 Negative_regulation of Binding of FLT1 and VEGFA 3 0.11 1.9 0 65.36
68 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 65.00
69 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27 65.00
70 INT221684 Binding of Bcl2 and FRTS 1 0.01 1.19 0.11 65.00
71 INT221683 Binding of Mki67 and FRTS 1 0.01 1.18 0.11 64.60
72 INT205155 Negative_regulation of Binding of CD44 and MMP9 1 0.32 1.98 0.23 64.56
73 INT280267 Tgfb1 Positive_regulation of Cxcr4 1 0.11 2.45 0.19 64.48
74 INT301401 Binding of Enpp1 and Enpp2 1 0.23 0.54 0 63.84
75 INT250665 EGFR Positive_regulation of PIK3CB 1 0.21 1.39 0 63.80
76 INT219875 Binding of KRT7 and Krt20 1 0.01 1.32 0.04 63.64
77 INT219857 Binding of Krt20 and Nbr1 1 0.00 1.31 0.04 63.44
78 INT250666 ERBB2 Positive_regulation of PIK3CB 1 0.15 0.69 0 61.72
79 INT277836 EGFR Positive_regulation of VEGFA 1 0.24 0.47 0 61.52
80 INT343159 ACSL4 Regulation of Gene_expression of LOX 1 0.07 1.04 0 61.16
81 INT343162 ACSL4 Regulation of LOX 1 0.03 1.04 0 60.76
82 INT343155 ACSL4 Regulation of CPOX 1 0.01 1.03 0 60.44
83 INT19633 GNRH1 Regulation of Localization of CGA 4 0.44 0.82 1.33 60.00
84 INT172568 Gene_expression of GNRH1 Regulation of Localization of CGA 1 0.05 0.66 0.08 60.00
85 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85 59.84
86 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11 56.20
87 INT315161 Egfr Negative_regulation of Erbb2 1 0.36 0.83 0 55.24
88 INT315167 Egfr Negative_regulation of Mapk3 1 0.04 0.83 0 55.24
89 INT315169 Egfr Negative_regulation of PCNA 1 0.03 0.84 0 55.24
90 INT315160 Egfr Negative_regulation of Myc 1 0.45 0.84 0 55.24
91 INT315162 Egfr Negative_regulation of Akt1 1 0.17 0.83 0 55.24
92 INT315163 Erbb2 Negative_regulation of Akt1 1 0.17 0.83 0 55.04
93 INT315159 Erbb2 Negative_regulation of Myc 1 0.43 0.84 0 55.04
94 INT315166 Erbb2 Negative_regulation of Egfr 1 0.36 0.83 0 55.04
95 INT315168 Erbb2 Negative_regulation of Mapk3 1 0.03 0.83 0 55.04
96 INT315170 Erbb2 Negative_regulation of PCNA 1 0.03 0.84 0 55.04
97 INT250660 PIK3CB Negative_regulation of AKT1 1 0.09 0.83 0 55.00
98 INT115609 Binding of ERBB2 and SFRP5 3 0.15 1.83 0 53.00
99 INT186603 Binding of ERBB2 and Ednra 1 0.02 0.53 0 51.60
100 INT230761 VEGFA Positive_regulation of Kdr 2 0.02 2.16 0.12 51.48
101 INT345375 VEGFA Positive_regulation of Gene_expression of Kdr 1 0.02 1.2 0 51.48
102 INT345374 VEGFA Positive_regulation of Flt4 1 0.01 2.95 0 51.48
103 INT250661 Binding of EGF and ERBB2 2 0.11 0.82 0.08 50.56
104 INT343547 ROCK1 Positive_regulation of Gene_expression of PTHLH 1 0.15 0.2 0.2 50.00
105 INT343542 ROCK1 Positive_regulation of Positive_regulation of PTHLH 1 0.21 0 0.12 50.00
106 INT343538 TGFB1 Positive_regulation of Gene_expression of GLI2 1 0.08 0.2 0.05 50.00
107 INT343540 Binding of PPP1R12A and MLC1 1 0.09 0.15 0.04 50.00
108 INT343545 Binding of GLI2 and ROCK1 1 0.07 0.65 0.03 50.00
109 INT343537 ROCK1 Regulation of Gene_expression of PTHLH 1 0.08 0.09 0.03 50.00
110 INT343544 Negative_regulation of GLI2 Negative_regulation of Gene_expression of PTHLH 1 0.24 0.53 0.03 50.00
111 INT343541 PTHLH Positive_regulation of GYPA 1 0.03 0.95 0 50.00
112 INT343548 GLI2 Positive_regulation of Gene_expression of PTHLH 1 0.28 0.94 0 50.00
113 INT343549 GLI2 Positive_regulation of GYPA 1 0.05 0.95 0 50.00
114 INT343539 GLI2 Regulation of PTHLH 1 0.15 0.25 0 50.00
115 INT175401 Binding of EGFR and VEGFA 2 0.13 1.49 0.13 44.72
116 INT250718 PIK3CB Regulation of Gene_expression of Birc5 1 0.23 0.91 0 43.48
117 INT186589 Binding of ERBB2 and SCFV 1 0.13 0.65 0 41.12
118 INT277860 MUC4 Negative_regulation of ERBB2 1 0.19 0.29 0 39.68
119 INT301414 Binding of Enpp2 and Twist1 1 0.08 1.26 0.13 39.00
120 INT301413 Positive_regulation of Binding of Enpp2 and Twist1 1 0.11 0.18 0.03 39.00
121 INT301415 Positive_regulation of Binding of Twist1 and IL19 1 0.11 0.18 0.03 38.36
122 INT301416 Binding of Twist1 and IL19 1 0.08 0.18 0.03 38.36
123 INT301408 Positive_regulation of Binding of Enpp1 and Twist1 1 0.06 0.18 0.03 38.04
124 INT301406 Binding of Enpp1 and Twist1 1 0.04 0.18 0.03 38.04
125 INT250657 STAT3 Positive_regulation of Gene_expression of VEGFA 1 0.07 0.74 0 36.88
126 INT250656 ELK1 Positive_regulation of Gene_expression of VEGFA 1 0.07 0.74 0 36.16
127 INT250658 FOS Positive_regulation of CCND1 1 0.03 0.6 0 35.84
128 INT351086 Negative_regulation of ERBB2 Positive_regulation of Gene_expression of ESR1 1 0.10 0.75 0.19 30.16
129 INT351088 Negative_regulation of ERBB2 Positive_regulation of FOXO3 1 0.17 0.66 0.18 30.16
130 INT340726 SERPINB1 Regulation of CSPG5 1 0.00 0.35 0.05 28.56
131 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 27.36
132 INT351089 FOXO3 Positive_regulation of Gene_expression of ESR1 1 0.04 0.74 0.19 26.60
133 INT280276 Binding of Tgfb1 and Positive_regulation of VEGFA 1 0.02 1.27 0 25.24
134 INT79162 Binding of TNC and PLG 1 0.28 0.23 0 25.00
135 INT79160 Binding of PLG and CLEC3B Positive_regulation of Positive_regulation of PLG 1 0.42 0.25 0 25.00
136 INT280262 Binding of Tgfb1 and Positive_regulation of Cxcr4 1 0.07 1.27 0 24.68
137 INT337626 Binding of PLAU and CLEC3B 1 0.20 0.4 0 22.48
138 INT343161 ACSL4 Regulation of Gene_expression of TSPO 1 0.25 0.75 0 19.12
139 INT184191 IL1B Positive_regulation of Gene_expression of SPAM1 1 0.03 0.59 0.23 19.04
140 INT184192 IL1B Positive_regulation of SPAM1 1 0.04 0.49 0.24 18.48
141 INT337630 Binding of PLAT and PLG 1 0.07 0.69 0 17.68
142 INT337629 Binding of PLAT and CLEC3B 1 0.23 0.35 0 17.68
143 INT337628 Binding of HGF and PLG 1 0.17 0.69 0 17.04
144 INT337631 Binding of HGF and CLEC3B 1 0.42 0.35 0 17.04
145 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56 10.76
146 INT298638 IL6 Positive_regulation of IL6R 1 0.00 0.9 0.05 10.76
147 INT250659 Negative_regulation of PTEN Positive_regulation of Positive_regulation of PIK3CB 1 0.02 1.18 0 8.36
148 INT337632 PLAU Positive_regulation of PLG 1 0.07 0.36 0 8.08
149 INT191059 Bcl2 Positive_regulation of Localization of Il12a 1 0.16 0.77 0 7.84
150 INT182194 Binding of IL8 and CXCR2 10 0.56 7.14 4.16 5.00
151 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
152 INT208572 Binding of IL8 and CXCR1 6 0.33 5.2 3.08 5.00
153 INT134212 CRH Regulation of Localization of POMC 1 0.47 2.89 2.9 5.00
154 INT231392 Enpp2 Positive_regulation of Gene_expression of Lpar1 2 0.38 2.19 0.93 5.00
155 INT232417 Binding of Mtx1 and Ifx 1 0.04 0.99 0.86 5.00
156 INT196525 Binding of MMP2 and MMP9 2 0.32 2.49 0.78 5.00
157 INT113552 Binding of PLAU and PLAUR 4 0.31 3.09 0.72 5.00
158 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69 5.00
159 INT318737 Binding of CXCR1 and CXCL6 1 0.25 1.37 0.67 5.00
160 INT318738 Binding of CXCR2 and CXCL6 1 0.32 1.39 0.67 5.00
161 INT184193 HRAS Negative_regulation of Gene_expression of IL1B 1 0.00 1.12 0.65 5.00
162 INT145661 Ptger2 Positive_regulation of Gene_expression of VEGFA 4 0.27 2.73 0.6 5.00
163 INT333991 Binding of FLNA and SELL 1 0.00 1.69 0.55 5.00
164 INT263917 Binding of SST and Sstr5 2 0.02 0.56 0.45 5.00
165 INT196348 PTGER2 Negative_regulation of Negative_regulation of MMP2 1 0.01 0.29 0.43 5.00
166 INT236110 Binding of Ppara and Olfm4 1 0.00 1.22 0.4 5.00
167 INT236111 Binding of Pdpk1 and Ppara 1 0.26 1.21 0.39 5.00
168 INT166792 Binding of CD44 and HRAS 3 0.12 1.49 0.37 5.00
169 INT178217 IFNA1 Regulation of Cxcl10 1 0.01 0.86 0.37 5.00
170 INT178218 IFNA1 Regulation of Tlr7 1 0.04 0.87 0.37 5.00
171 INT133307 Binding of CD44 and SPP1 5 0.26 2.6 0.35 5.00
172 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34 5.00
173 INT89381 INS Positive_regulation of AKT1 6 0.43 3.06 0.33 5.00
174 INT333993 Binding of Vcam1 and Vwf 1 0.00 1.32 0.33 5.00
175 INT326089 Gopc Positive_regulation of Mmp9 1 0.03 0.63 0.33 5.00
176 INT326090 Binding of Erbb2 and Mmp2 1 0.09 1.39 0.31 5.00
177 INT320794 Binding of VEGFA and Flt4 4 0.08 3.04 0.27 5.00
178 INT326094 Akt1 Positive_regulation of Gene_expression of Gopc 1 0.03 0.49 0.24 5.00
179 INT326092 Gene_expression of Akt1 Negative_regulation of Gopc 1 0.03 0.55 0.24 5.00
180 INT326093 Akt1 Positive_regulation of Gopc 1 0.03 0.43 0.23 5.00
181 INT252357 Binding of THBS1 and Cd36 2 0.01 2.4 0.21 5.00
182 INT192219 CASP3 Regulation of ESR1 1 0.03 1.19 0.19 5.00
183 INT184194 Binding of HRAS and SPAM1 1 0.00 0.26 0.17 5.00
184 INT298641 PPARA Regulation of STAT3 1 0.23 0.98 0.16 5.00
185 INT326097 WAS Regulation of Gopc 1 0.01 0.55 0.16 5.00
186 INT263901 Binding of Ighg1 and Slc3a2 1 0.00 0.89 0.16 5.00
187 INT203591 Positive_regulation of PIK3CG Positive_regulation of Protein_catabolism of LAMB2 1 0.00 0.46 0.14 5.00
188 INT188249 PLAT Positive_regulation of PLG 2 0.10 0.86 0.14 5.00
189 INT298639 GDE1 Negative_regulation of AKT1 1 0.00 1.14 0.14 5.00
190 INT175398 Binding of ERBB2 and VEGFA 2 0.16 1.34 0.13 5.00
191 INT184527 Binding of DUS2L and HEPACAM 1 0.00 0.86 0.13 5.00
192 INT184522 Positive_regulation of Ptger2 Regulation of Localization of Ccnd1 1 0.01 0.95 0.11 5.00
193 INT184521 Ptger2 Regulation of Localization of Ccnd1 1 0.01 0.94 0.11 5.00
194 INT287266 EGF Positive_regulation of EGF Positive_regulation of CDC42 1 0.06 0.16 0.11 5.00
195 INT184520 Ptger2 Regulation of Ccnd1 1 0.00 0.94 0.11 5.00
196 INT287267 EGF Positive_regulation of CDC42 1 0.12 0.16 0.11 5.00
197 INT271525 ITGB1 Positive_regulation of Gopc 1 0.02 0.57 0.11 5.00
198 INT203629 IL8 Negative_regulation of Timp1 1 0.05 0 0.1 5.00
199 INT203628 Cxcl1 Negative_regulation of TIMP2 1 0.01 0 0.1 5.00
200 INT293411 IL8 Regulation of IL11 1 0.03 1.17 0.1 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Advanced Or Metastatic Breast Cancer. They are ordered first by their pain relevance and then by number of times they were reported in Advanced Or Metastatic Breast Cancer. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 100.00
2 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23 100.00
3 INT52962 Binding of ERBB2 77 0.47 50.03 1.49 100.00
4 INT251788 Gene_expression of ESYT1 8 0.06 7.29 0.23 100.00
5 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 100.00
6 INT251787 Positive_regulation of ESYT1 1 0.05 3.77 0.17 100.00
7 INT172529 Negative_regulation of Gene_expression of PGR 24 0.48 16.69 1.04 100.00
8 INT207203 Transcription of Akt1 6 0.67 3.73 1.1 100.00
9 INT181856 Gene_expression of SPAM1 2 0.22 4.5 1.35 100.00
10 INT15048 Regulation of Cacna1c 4 0.29 3.26 1.47 100.00
11 INT66452 Positive_regulation of Cacna1c 6 0.19 2.56 1.08 100.00
12 INT119012 Gene_expression of CLEC14A 1 0.62 0.27 0.09 100.00
13 INT119011 Positive_regulation of Gene_expression of CLEC14A 1 0.40 0.27 0.09 100.00
14 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 99.98
15 INT144430 Gene_expression of Erbb2 137 0.77 103.87 8.66 99.98
16 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 99.98
17 INT144428 Positive_regulation of Gene_expression of Erbb2 41 0.69 41.4 4.13 99.98
18 INT184198 Positive_regulation of Gene_expression of SPAM1 1 0.14 0.42 0.18 99.98
19 INT21788 Positive_regulation of ERBB2 49 0.66 28.88 1.68 99.96
20 INT1926 Positive_regulation of PLAT 54 0.66 31.42 6.49 99.96
21 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 99.96
22 INT170601 Positive_regulation of Gene_expression of GOPC 122 0.43 42.79 11.68 99.96
23 INT324609 Negative_regulation of Gene_expression of SNCG 1 0.43 5.2 0 99.90
24 INT324607 Positive_regulation of Gene_expression of SNCG 1 0.61 10.34 0 99.90
25 INT11154 Binding of EGFR 149 0.48 96.23 6.29 99.88
26 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19 99.84
27 INT20462 Binding of ESR1 210 0.44 102.7 26.34 99.84
28 INT85084 Gene_expression of KRT19 66 0.73 42.56 1.82 99.84
29 INT11359 Gene_expression of PLAU 84 0.76 49.54 12.31 99.84
30 INT78320 Gene_expression of EPCAM 57 0.75 50.34 7.53 99.84
31 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 99.84
32 INT1921 Gene_expression of CEACAM7 47 0.78 43.23 2.53 99.84
33 INT92082 Regulation of Binding of ESR1 5 0.45 2.41 0.73 99.84
34 INT64123 Gene_expression of PIP 16 0.70 5.77 0.86 99.84
35 INT76217 Gene_expression of Spdef 13 0.62 4.86 2.32 99.84
36 INT122901 Positive_regulation of Spp1 67 0.67 58.03 7.49 99.84
37 INT102234 Gene_expression of ESR2 17 0.65 9.29 2.3 99.84
38 INT176512 Positive_regulation of Ibsp 2 0.30 1.11 0 99.84
39 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 99.80
40 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 99.80
41 INT1922 Positive_regulation of CEACAM7 32 0.70 33.31 2.72 99.80
42 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9 99.80
43 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 99.74
44 INT37652 Positive_regulation of Pgr 29 0.59 9.09 4.67 99.74
45 INT105781 Positive_regulation of Krt7 4 0.04 3.34 0.3 99.74
46 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 99.72
47 INT131850 Gene_expression of RHOC 17 0.72 29.06 2.28 99.72
48 INT131848 Positive_regulation of Gene_expression of RHOC 9 0.64 15.43 1.36 99.72
49 INT184201 Positive_regulation of SPAM1 1 0.13 0.26 0.08 99.72
50 INT109005 Gene_expression of Proc 61 0.75 37.86 8.49 99.70
51 INT234676 Gene_expression of SNCG 4 0.78 63.59 0.08 99.64
52 INT93886 Positive_regulation of Gene_expression of PGR 19 0.52 15.78 1.89 99.64
53 INT173808 Positive_regulation of CYP27A1 35 0.68 23.7 7.87 99.64
54 INT123458 Positive_regulation of Tnfrsf11b 9 0.43 14.3 2.01 99.60
55 INT78199 Gene_expression of Neu1 65 0.75 62.88 7.16 99.56
56 INT133630 Negative_regulation of Gene_expression of ESR1 42 0.52 23.89 4.57 99.52
57 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18 99.52
58 INT99610 Localization of MMP9 126 0.79 48.46 32.67 99.48
59 INT213924 Regulation of Binding of ERBB2 1 0.43 0.46 0 99.44
60 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 99.40
61 INT61118 Gene_expression of Nefl 11 0.75 4.02 4.02 99.40
62 INT221674 Localization of Erbb2 2 0.38 1.28 0.07 99.36
63 INT80174 Positive_regulation of Gene_expression of Neu1 23 0.37 17.82 1.12 99.28
64 INT15921 Positive_regulation of Serpine1 85 0.68 81.24 13.4 99.28
65 INT67884 Positive_regulation of PLAU 15 0.68 11.21 2.61 99.28
66 INT105222 Positive_regulation of Plau 18 0.54 8.52 3.5 99.28
67 INT11635 Positive_regulation of Gene_expression of SERPINE1 35 0.68 24.57 4.26 99.28
68 INT115721 Positive_regulation of Gene_expression of PLAU 11 0.67 7.66 1.55 99.28
69 INT167085 Negative_regulation of ERBB2 67 0.57 44.6 1.48 99.24
70 INT213124 Regulation of RRAD 2 0.01 1.3 0 99.24
71 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 99.16
72 INT122481 Binding of PLAU 10 0.36 6.1 1.16 99.10
73 INT111984 Gene_expression of Il24 4 0.08 4.06 1.28 99.00
74 INT56443 Gene_expression of GHRHR 2 0.06 2.13 0.27 99.00
75 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97 98.96
76 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 98.84
77 INT2197 Gene_expression of Gnrh1 184 0.78 40.04 50.57 98.82
78 INT37800 Positive_regulation of Apob 7 0.18 11.01 0.48 98.76
79 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 98.72
80 INT139382 Gene_expression of CELSR2 6 0.37 4.72 0.71 98.72
81 INT226581 Positive_regulation of Gene_expression of CELSR2 3 0.13 2.86 0 98.72
82 INT546 Binding of ALB 311 0.48 85.98 60.14 98.72
83 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 98.70
84 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 98.66
85 INT90673 Gene_expression of LOX 66 0.65 69.71 12.18 98.64
86 INT263822 Positive_regulation of Gene_expression of LOX 8 0.50 11 1.06 98.64
87 INT16323 Gene_expression of pr 62 0.66 36.14 38.26 98.52
88 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 98.42
89 INT84809 Positive_regulation of Gene_expression of MUC1 39 0.70 36.42 3.75 98.40
90 INT113568 Protein_catabolism of PLAU 5 0.94 4.79 0.57 98.40
91 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 98.36
92 INT71002 Gene_expression of ALOX15 21 0.78 21.16 6.37 98.36
93 INT176523 Localization of Ibsp 1 0.03 0.88 0 98.20
94 INT39468 Positive_regulation of hf 10 0.33 13.5 1.32 98.14
95 INT17444 Gene_expression of MTHFS 14 0.66 5.17 3.85 98.08
96 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 98.04
97 INT147583 Gene_expression of AIS 82 0.58 48.7 7.11 98.00
98 INT202194 Transcription of Krt19 1 0.54 13.99 2.61 98.00
99 INT88718 Negative_regulation of Erbb2 11 0.58 12.98 0.84 98.00
100 INT202193 Gene_expression of Krt19 4 0.45 5.02 1.17 98.00
101 INT120562 Negative_regulation of Egfr 108 0.59 79.38 3.11 98.00
102 INT223597 Negative_regulation of Binding of EGFR 12 0.43 7.97 0.23 97.96
103 INT118291 Binding of TXK 19 0.10 11.77 1.94 97.96
104 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74 97.96
105 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03 97.96
106 INT52311 Positive_regulation of JUNB 12 0.40 4.48 6.02 97.96
107 INT181781 Positive_regulation of FOSB 6 0.39 4.77 0.34 97.96
108 INT49660 Positive_regulation of EGR1 54 0.69 32.17 9.89 97.96
109 INT54000 Positive_regulation of SNAI1 7 0.49 5.37 0.58 97.96
110 INT20806 Positive_regulation of MYCN 3 0.45 1.34 0.45 97.96
111 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 97.88
112 INT1976 Regulation of Gene_expression of Prl 80 0.62 20.19 36 97.88
113 INT172523 Gene_expression of WISP3 3 0.73 11.72 1.39 97.84
114 INT439 Localization of Gnrh1 976 0.81 100.96 363.25 97.84
115 INT847 Regulation of Lhb 131 0.61 22.08 46.54 97.80
116 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 97.80
117 INT183389 Regulation of Apob 4 0.01 5.17 0.05 97.76
118 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 97.76
119 INT1919 Regulation of Regulation of CEACAM7 1 0.23 0.98 0.1 97.74
120 INT251791 Transcription of IGHD1-7 1 0.05 1.1 0.11 97.62
121 INT19132 Gene_expression of CYP27A1 83 0.75 34.31 10.17 97.60
122 INT16445 Gene_expression of IL1A 60 0.78 44.46 19.19 97.60
123 INT162 Regulation of Prl 794 0.62 165.01 322.24 97.60
124 INT157747 Gene_expression of SLC22A16 2 0.65 0.35 0.05 97.56
125 INT1924 Regulation of PLAT 11 0.60 6.3 3.16 97.52
126 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 97.48
127 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 97.44
128 INT120722 Gene_expression of TYMP 35 0.75 19.26 1.31 97.36
129 INT1923 Regulation of CEACAM7 9 0.41 7.36 0.31 97.36
130 INT67006 Positive_regulation of TTPA 5 0.49 2.31 1.29 97.16
131 INT194794 Binding of TTPA 7 0.08 2.56 0.57 97.16
132 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 97.12
133 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46 97.12
134 INT71763 Gene_expression of Mri1 33 0.58 12.56 8.6 97.08
135 INT117348 Regulation of EGFR 75 0.61 47.73 3.09 97.04
136 INT223599 Regulation of MTOR 14 0.42 8.52 0.49 97.04
137 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 97.04
138 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16 97.04
139 INT135806 Regulation of Bcl2l1 10 0.44 7.21 1.05 97.04
140 INT11160 Regulation of Gene_expression of EGFR 27 0.62 22.05 0.96 96.88
141 INT38828 Negative_regulation of STS 14 0.44 7.27 0.68 96.88
142 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43 96.84
143 INT37296 Binding of Esr1 117 0.43 62.51 27.33 96.76
144 INT339167 Positive_regulation of Localization of ERBB2 2 0.49 1.49 0.17 96.72
145 INT5847 Transcription of FOS 31 0.69 11.11 6.41 96.68
146 INT67936 Transcription of JUN 18 0.52 9.52 4.13 96.68
147 INT181789 Transcription of FOSB 3 0.58 2.71 0.24 96.68
148 INT181786 Transcription of JUNB 3 0.59 2.31 0.19 96.68
149 INT57376 Transcription of EGR1 20 0.69 12.94 4.84 96.68
150 INT20803 Transcription of MYCN 2 0.57 1.2 0.26 96.68
151 INT181783 Transcription of SNAI1 3 0.71 2.44 0.17 96.68
152 INT176516 Localization of Spp1 28 0.76 19.39 1.9 96.68
153 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 96.64
154 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66 96.64
155 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 96.52
156 INT154312 Gene_expression of STON1 3 0.54 3.17 1 96.52
157 INT78190 Gene_expression of Tnc 10 0.75 21.23 2.91 96.52
158 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21 96.48
159 INT133809 Negative_regulation of Gene_expression of CYP19A1 9 0.43 7.67 2.99 96.48
160 INT123459 Gene_expression of Tnfrsf11b 35 0.58 24.16 7.26 96.44
161 INT11636 Positive_regulation of SERPINE1 85 0.69 68.73 14.8 96.26
162 INT136503 Negative_regulation of KDR 46 0.48 43.1 1.86 96.20
163 INT178210 Localization of STON1 1 0.07 1.26 0 96.12
164 INT178199 Localization of Tnc 2 0.78 5.29 0.16 96.12
165 INT250715 Positive_regulation of ST8SIA4 2 0.09 0.82 0.04 96.12
166 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 96.08
167 INT71649 Localization of ERBB2 23 0.78 13.63 0.83 96.08
168 INT131773 Regulation of KDR 12 0.49 12.01 0.39 96.08
169 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 96.08
170 INT251796 Regulation of FLT3 2 0.35 3.11 0.03 96.08
171 INT113705 Gene_expression of Egfr 228 0.78 149.05 7.59 96.08
172 INT138556 Positive_regulation of TYMP 23 0.58 12.9 0.28 95.96
173 INT131457 Gene_expression of FCGR1A 11 0.75 4.88 1.45 95.84
174 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 95.80
175 INT10824 Negative_regulation of Cyp19a1 38 0.57 25.18 3.56 95.80
176 INT49802 Localization of MUC1 75 0.81 44.74 8.87 95.52
177 INT188844 Gene_expression of AES 44 0.58 33.94 5.85 95.44
178 INT200442 Positive_regulation of Gene_expression of AES 5 0.42 5.12 0.48 95.44
179 INT199661 Negative_regulation of TTPA 2 0.04 1.84 0 95.44
180 INT124944 Regulation of KIT 15 0.60 11.84 0.24 95.40
181 INT192340 Regulation of PDGFRB 4 0.45 3.83 0.03 95.40
182 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89 95.16
183 INT232970 Localization of KRT19 4 0.41 3.41 0.23 95.16
184 INT54617 Positive_regulation of Gene_expression of Abcb1b 22 0.67 9.8 5.34 95.12
185 INT147162 Positive_regulation of Abcb1b 13 0.57 7.29 1.15 95.12
186 INT179523 Binding of Pip 4 0.14 2.61 0.64 95.12
187 INT302180 Positive_regulation of Gene_expression of Abcg2 6 0.61 3.13 0.43 95.12
188 INT307936 Positive_regulation of Abcg2 3 0.57 1.92 0.08 95.12
189 INT173811 Regulation of Gene_expression of CYP27A1 3 0.44 0.78 0 95.04
190 INT314710 Gene_expression of ZNF639 1 0.01 1 0 94.96
191 INT12104 Positive_regulation of PLG 45 0.68 28.94 4.81 94.92
192 INT201130 Localization of AES 31 0.63 25.45 5.12 94.88
193 INT14778 Gene_expression of FCGR3A 25 0.75 16.25 3.86 94.84
194 INT140547 Negative_regulation of PSMB10 3 0.02 2.33 2.92 94.72
195 INT293487 Regulation of Gene_expression of Erbb2 4 0.61 3.4 1.06 94.72
196 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55 94.60
197 INT76752 Negative_regulation of TOP2B 8 0.42 6.2 0.14 94.52
198 INT8103 Binding of TP53 46 0.44 40.2 2.96 94.48
199 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 94.48
200 INT172555 Positive_regulation of Localization of Proc 1 0.00 1.82 0 94.48
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