D:Adverse Drug Reaction

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Disease Term
Synonyms Adverse Drug Effect, Adverse Drug Reactions, ADVERSE EFFECTS OF MEDICATION, Adverse Reaction To Drug, ADVERSE REACTIONS, Drug Reaction, DRUG SIDE EFFECT, MEDICATION SIDE EFFECT, Side Effect Medication
Documents 3444
Hot Single Events 200
Hot Interactions 10

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Adverse Drug Reaction. They are ordered first by their relevance to Adverse Drug Reaction and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT301665 CYP2C9 Regulation of Binding of Ppara 1 0.26 1.79 0.34 98.84
2 INT353191 Renbp Regulation of Gene_expression of Yif1 1 0.00 0.55 0 96.60
3 INT275123 Binding of HLA-E and SUGT1 1 0.00 0.93 0 90.96
4 INT233303 Binding of CD4 and SRY 1 0.07 0.34 0.05 90.48
5 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 90.20
6 INT231750 LOC690550 Negative_regulation of Jak3 1 0.02 1.3 0.52 89.40
7 INT166983 Binding of HLA-B and HSPG2 4 0.08 4.66 0.88 87.04
8 INT231751 Binding of Il2rg and Jak3 1 0.03 1.56 0.67 86.88
9 INT100783 Binding of CYP2B6 and CYP3A4 2 0.17 2 0.77 86.00
10 INT233304 Binding of SRY and SLC22A8 1 0.34 0.93 0 82.84
11 INT177358 Ptger1 Positive_regulation of Localization of AMY2A 1 0.00 0.56 0.54 78.88
12 INT177357 Ptger1 Positive_regulation of Gene_expression of AMY2A 1 0.00 0.56 0.54 78.88
13 INT351656 Enpep Regulation of Agt 1 0.20 1.2 0 78.56
14 INT87555 TPSAB1 Positive_regulation of IGHE 1 0.42 0.71 0.43 76.60
15 INT87556 TPSAB1 Positive_regulation of CD79A 1 0.40 0.7 0.42 74.88
16 INT145491 PROC Positive_regulation of Cpox 1 0.00 1.08 0.58 71.76
17 INT275126 Binding of CSTB and IGHG3 1 0.00 0.49 0.05 69.60
18 INT147774 Binding of HLA-B and ABCB6 2 0.40 1.03 0.08 66.12
19 INT300244 Binding of HLA-B and HSR 1 0.08 0.95 0 66.12
20 INT304010 Afw1 Negative_regulation of Gene_expression of ISYNA1 1 0.00 0.27 0.1 66.00
21 INT262231 Sfn Negative_regulation of Gene_expression of CYP3A4 1 0.06 0.26 0.14 64.40
22 INT262232 Nr1i2 Positive_regulation of Gene_expression of CYP3A4 1 0.17 0.26 0.14 64.40
23 INT188249 PLAT Positive_regulation of PLG 2 0.10 0.86 0.14 62.68
24 INT266811 Binding of HRH1 and HTR2C 1 0.23 2.06 1.4 61.80
25 INT115610 Binding of ERBB2 and KLF1 1 0.02 2.12 0.17 60.68
26 INT349077 Binding of HLA-E and KLRD1 1 0.00 0.16 0 60.48
27 INT72666 Binding of ODT and Oprm1 1 0.03 0.53 1.5 58.96
28 INT273197 Binding of BCR and COPD 1 0.03 0.4 0 58.56
29 INT210597 Negative_regulation of Binding of TNFSF11 and TNFRSF11A 3 0.26 5.66 0.33 57.56
30 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 56.92
31 INT262193 Binding of Nr1i2 and Sfn 1 0.15 0.26 0.13 56.40
32 INT228563 Grhpr Regulation of Negative_regulation of Coq10a 1 0.00 0.71 0 55.88
33 INT302883 Binding of TXN and Alb 1 0.06 4.13 0.1 54.48
34 INT319973 App Regulation of Gene_expression of Mapk12 1 0.02 0.98 0.04 53.36
35 INT262224 Sfn Negative_regulation of Transcription of CYP3A4 1 0.06 0.58 0.2 50.96
36 INT262228 Nr1i2 Positive_regulation of Transcription of CYP3A4 1 0.17 0.27 0.13 50.96
37 INT183750 Binding of EPO and TF 1 0.42 1.21 0 50.32
38 INT275125 Binding of HLA-DOA and HSPG2 1 0.01 1.42 0.04 50.00
39 INT275124 Binding of HSPG2 and LTA 1 0.12 1.45 0.04 50.00
40 INT224423 Binding of TNFRSF11B and TNFRSF11A 3 0.19 2.36 0.37 43.60
41 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86 42.88
42 INT158400 Binding of CD80 and CD86 3 0.36 0.76 0.48 42.60
43 INT349079 Binding of CD80 and Cd86 1 0.22 0 0 42.60
44 INT352627 Binding of IGHG3 and MAN2A1 1 0.00 1.48 0 40.00
45 INT262206 Sfn Negative_regulation of Nr1i2 1 0.17 0.28 0.12 39.68
46 INT210596 TNFRSF11B Negative_regulation of Binding of TNFSF11 2 0.11 1.62 0.04 34.72
47 INT210593 TNFRSF11B Negative_regulation of Binding of TNFSF11 and TNFRSF11A 2 0.10 1.62 0.04 34.72
48 INT228333 Binding of IFNA1 and IRF9 2 0.04 0.53 0.09 31.16
49 INT115611 Binding of EDNRA and ERBB2 1 0.08 0.78 0 29.44
50 INT115609 Binding of ERBB2 and SFRP5 3 0.15 1.83 0 29.44
51 INT215470 Binding of HLA-B and CRAMP1L 1 0.05 0.94 0 28.08
52 INT262413 Binding of EPHB1 and ADHD1 1 0.17 0.1 0 27.44
53 INT338940 Fpgs Positive_regulation of Mtx1 1 0.32 0.32 0.47 26.44
54 INT109502 GBE1 Negative_regulation of HIVEP1 1 0.00 1.85 0 25.00
55 INT271873 IL10 Regulation of Gene_expression of IK 1 0.00 0.81 0.47 23.12
56 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 22.64
57 INT271872 IL10 Regulation of IK 1 0.00 0.81 0.47 22.40
58 INT329479 Binding of TNFRSF11B and TNF 1 0.04 0.71 0 20.04
59 INT329480 Binding of TNFRSF11B and TNFSF10 1 0.03 0.71 0 20.04
60 INT264101 Binding of CYP2D6 and Bche 1 0.07 0.33 0.18 16.32
61 INT178861 Binding of BAX and BCL2 3 0.27 3.07 0 14.60
62 INT271874 IL10 Negative_regulation of TNF 1 0.07 0.78 0.5 9.28
63 INT264085 CYP2C19 Regulation of CYP3A4 1 0.02 0 0.09 8.56
64 INT264102 Cyp1a2 Regulation of CYP3A4 1 0.03 0 0.09 8.56
65 INT264105 Cyp2e1 Regulation of CYP3A4 1 0.02 0 0.09 8.56
66 INT264106 Cyp1a2 Regulation of CYP2D6 1 0.06 0 0.09 8.24
67 INT264083 CYP2C19 Regulation of CYP2D6 1 0.05 0 0.09 8.24
68 INT264107 Cyp2e1 Regulation of CYP2D6 1 0.05 0 0.09 8.24
69 INT264103 Cyp2e1 Regulation of CYP2C9 1 0.04 0 0.09 7.92
70 INT264104 Cyp1a2 Regulation of CYP2C9 1 0.04 0 0.09 7.92
71 INT264084 CYP2C19 Regulation of CYP2C9 1 0.03 0 0.09 7.92
72 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
73 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
74 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 5.00
75 INT186128 Binding of CD2 and CD58 8 0.10 7.59 2.76 5.00
76 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41 5.00
77 INT319581 Binding of PIAS1 and TNFSF14 1 0.02 1.58 2.13 5.00
78 INT97208 Binding of Gabrg1 and Gabbr1 2 0.07 0.31 1.94 5.00
79 INT105917 Binding of SLC22A6 and SLC22A8 2 0.31 0.34 1.67 5.00
80 INT194863 Binding of IL1R1 and IL1RN 5 0.09 2.23 1.64 5.00
81 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53 5.00
82 INT229094 Binding of IL1RN and Il1r1 1 0.01 1.9 1.5 5.00
83 INT262377 Binding of Comt and Fmod 1 0.06 1.47 1.29 5.00
84 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22 5.00
85 INT105918 Binding of FUT1 and SLC9A3R2 1 0.00 0.14 1.2 5.00
86 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07 5.00
87 INT353741 Binding of IGHE and Aia1 1 0.00 1.16 1.06 5.00
88 INT338894 TNFSF14 Negative_regulation of Gsk3a 1 0.00 0.54 1.04 5.00
89 INT271875 IL1RN Negative_regulation of Binding of IL1B 1 0.01 1.3 1.01 5.00
90 INT338892 TNFSF14 Regulation of Abat 1 0.00 0.61 1.01 5.00
91 INT338895 TNFSF14 Regulation of Regulation of Abat 1 0.00 0.62 1.01 5.00
92 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 5.00
93 INT36683 Gh1 Regulation of Gnrhr 3 0.08 1.25 0.95 5.00
94 INT232426 HRH2 Regulation of Localization of PRL 1 0.15 0.38 0.94 5.00
95 INT338893 TNFSF14 Positive_regulation of Gene_expression of Gria1 1 0.07 0.59 0.94 5.00
96 INT262165 Nr0b2 Negative_regulation of Nr5a2 1 0.02 0.5 0.92 5.00
97 INT115656 Glp1r Positive_regulation of Localization of Ins1 2 0.42 5.23 0.91 5.00
98 INT123229 OXTR Regulation of Localization of PRL 2 0.30 0 0.73 5.00
99 INT111080 Binding of CA1 and CA2 2 0.02 1.62 0.73 5.00
100 INT177359 Serpinc1 Positive_regulation of CSRP1 1 0.00 0.97 0.72 5.00
101 INT260551 Igh-Dex Negative_regulation of Il6 1 0.09 0.37 0.72 5.00
102 INT261378 Nsdhl Negative_regulation of Gene_expression of Flvcr2 1 0.01 0.34 0.7 5.00
103 INT229085 IL1RN Negative_regulation of Positive_regulation of IL1R1 1 0.12 1.72 0.68 5.00
104 INT185997 Binding of FANCB and fc 2 0.01 2.51 0.63 5.00
105 INT89902 SST Positive_regulation of Localization of PRL 2 0.40 0 0.61 5.00
106 INT316831 CCL5 Positive_regulation of Gene_expression of MMP2 1 0.02 0.51 0.59 5.00
107 INT175700 Nos3 Negative_regulation of smc 1 0.01 1.05 0.59 5.00
108 INT315334 Binding of CYP3A4 and CDIPT 3 0.04 0.85 0.59 5.00
109 INT261372 Gsk3b Regulation of Gene_expression of Ifi205 1 0.00 0.24 0.58 5.00
110 INT232424 VIP Positive_regulation of Localization of PRL 1 0.36 0 0.53 5.00
111 INT106744 Binding of CRP and EGFL7 2 0.07 2.35 0.51 5.00
112 INT172081 TNF Regulation of IFNA1 1 0.03 1.13 0.5 5.00
113 INT229095 Binding of IL1R1 and Il1r1 1 0.00 0.64 0.5 5.00
114 INT172082 TNF Regulation of SFTPA1 1 0.05 0.85 0.5 5.00
115 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5 5.00
116 INT288376 IL17A Regulation of VEGFA 1 0.00 1.16 0.49 5.00
117 INT36684 Gh1 Regulation of Prl 2 0.18 1.25 0.48 5.00
118 INT352031 Binding of NR3C1 and JUND 1 0.10 2.87 0.48 5.00
119 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48 5.00
120 INT341428 EPO Positive_regulation of NGF 1 0.52 0.37 0.48 5.00
121 INT341427 EPO Positive_regulation of BDNF 1 0.52 0.36 0.48 5.00
122 INT341426 EPO Regulation of NGF 1 0.51 0.5 0.47 5.00
123 INT341425 EPO Regulation of BDNF 1 0.51 0.5 0.47 5.00
124 INT239474 Binding of ACR and Ifx 1 0.02 0.36 0.45 5.00
125 INT262155 Nr5a2 Positive_regulation of Cyp7a1 1 0.07 0.24 0.45 5.00
126 INT232427 ABAT Regulation of PRL 1 0.08 0.26 0.45 5.00
127 INT193219 Binding of LTC4S and CYSLTR2 2 0.28 2.2 0.44 5.00
128 INT262220 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Abcc2 1 0.14 0.25 0.44 5.00
129 INT241853 Binding of SLC40A1 and HAMP 3 0.41 5.35 0.43 5.00
130 INT231749 Binding of Cia1 and LOC690550 1 0.00 0.98 0.43 5.00
131 INT121850 CASP8 Positive_regulation of Protein_catabolism of BID 2 0.21 1.81 0.43 5.00
132 INT261374 Nsdhl Regulation of Esr2 1 0.05 0.76 0.41 5.00
133 INT353730 Binding of FCGR2A and FCGR3A 1 0.33 0.5 0.41 5.00
134 INT231752 TNF Regulation of Il6 1 0.05 0.99 0.41 5.00
135 INT261370 Nsdhl Regulation of Esr1 1 0.01 0.75 0.41 5.00
136 INT351237 HRAS Regulation of CBL 1 0.00 0.48 0.4 5.00
137 INT262186 Nr0b2 Positive_regulation of Negative_regulation of Cyp7a1 1 0.12 0.28 0.4 5.00
138 INT231753 Il7 Positive_regulation of TNF 1 0.03 0.66 0.39 5.00
139 INT316830 TNF Regulation of CCL5 1 0.02 1.02 0.39 5.00
140 INT262205 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Cyp3a11 1 0.33 0.11 0.38 5.00
141 INT181862 Binding of MPO and PRTN3 2 0.16 1.18 0.38 5.00
142 INT262153 Binding of Clta and Nr1i2 1 0.05 0.65 0.38 5.00
143 INT232422 VIP Regulation of Gene_expression of PRL 1 0.40 0 0.37 5.00
144 INT340850 Binding of IGHE and Baat 1 0.07 0.27 0.37 5.00
145 INT232421 Binding of PRL and Positive_regulation of Regulation of ABAT 1 0.09 0 0.37 5.00
146 INT245328 Binding of Esr2 and Pgr 1 0.03 0.41 0.37 5.00
147 INT262182 Positive_regulation of Nr1i2 Negative_regulation of Gene_expression of Cyp7a1 1 0.23 0.36 0.36 5.00
148 INT262189 Binding of Nr1i2 and Nr1h4 1 0.14 0.18 0.36 5.00
149 INT231748 LOC690550 Negative_regulation of Il6 1 0.01 0.95 0.36 5.00
150 INT228922 Binding of Prf1 and RCT 1 0.08 0.36 0.36 5.00
151 INT285598 Maoa Negative_regulation of Aldh3a1 1 0.01 0.18 0.36 5.00
152 INT262218 Nr1h4 Regulation of Nr1i2 1 0.10 0.15 0.34 5.00
153 INT232419 ABAT Positive_regulation of Localization of PRL 1 0.09 0 0.33 5.00
154 INT229087 IL1R1 Negative_regulation of ACCS 1 0.03 0.86 0.33 5.00
155 INT232425 Binding of ABAT and Positive_regulation of PRL 1 0.09 0.15 0.33 5.00
156 INT318299 Binding of F2 and PRTN3 1 0.01 1.92 0.33 5.00
157 INT232420 PRL Positive_regulation of Regulation of ABAT 1 0.09 0 0.33 5.00
158 INT260433 Dbi Positive_regulation of Cd8a 1 0.00 0.13 0.3 5.00
159 INT260438 Binding of Cd4 and Mx1 1 0.00 1.52 0.29 5.00
160 INT260434 Binding of Cd8a and Mx1 1 0.00 1.52 0.29 5.00
161 INT262208 Clta Positive_regulation of Nr1i2 1 0.09 0.59 0.29 5.00
162 INT279265 Binding of MEFV and NLRP3 1 0.07 2.79 0.28 5.00
163 INT301666 Binding of CYP4F2 and Ltb4r1 1 0.02 0.57 0.28 5.00
164 INT279266 CADPS Positive_regulation of Regulation of IL1B 1 0.22 1.43 0.28 5.00
165 INT301668 Ltb4r1 Positive_regulation of Gene_expression of IL8 1 0.00 0.9 0.27 5.00
166 INT262144 Nr1h4 Positive_regulation of Positive_regulation of Nr1i2 1 0.19 0.19 0.27 5.00
167 INT262194 Rhof Positive_regulation of Nr1i2 1 0.15 0.64 0.27 5.00
168 INT321601 Binding of C3 and PRTN3 1 0.00 0.99 0.27 5.00
169 INT301671 Ltc4s Positive_regulation of Gene_expression of IL8 1 0.00 0.9 0.27 5.00
170 INT321602 Binding of C4A and PRTN3 1 0.00 0.99 0.27 5.00
171 INT262164 Positive_regulation of Rhof Positive_regulation of Nr1i2 1 0.11 0.65 0.27 5.00
172 INT262809 Il10 Positive_regulation of Regulation of Slc11a1 1 0.17 1.12 0.27 5.00
173 INT301670 Binding of CYP4F2 and Cyp4f18 1 0.02 1.04 0.27 5.00
174 INT71904 Binding of ESR1 and PGR 6 0.34 3.79 0.27 5.00
175 INT262810 Slc11a1 Positive_regulation of Gene_expression of Il10 1 0.20 0.97 0.27 5.00
176 INT338941 Binding of Ggh and Mtx1 1 0.30 0.47 0.27 5.00
177 INT260423 IFNA1 Positive_regulation of Gene_expression of VEGFA 1 0.01 1.28 0.26 5.00
178 INT262227 Nr1h4 Regulation of Transcription of CYP3A4 1 0.08 0.12 0.26 5.00
179 INT317773 Positive_regulation of GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25 5.00
180 INT262202 Nr1i2 Regulation of Abcc2 1 0.19 0.12 0.25 5.00
181 INT262180 Nr1h4 Regulation of Sult2a1 1 0.11 0.11 0.25 5.00
182 INT317775 GATA3 Positive_regulation of HDAC1 1 0.23 0.69 0.25 5.00
183 INT262152 Nr1h4 Regulation of Abcc2 1 0.07 0.12 0.25 5.00
184 INT261375 Binding of Nsdhl and Pparg 1 0.05 1.03 0.25 5.00
185 INT262200 Nr1i2 Regulation of Sult2a1 1 0.31 0.12 0.25 5.00
186 INT317771 GSR Positive_regulation of HDAC1 1 0.10 0.69 0.25 5.00
187 INT262167 Binding of Nr1i2 and Nr0b2 1 0.15 0.11 0.25 5.00
188 INT317776 Positive_regulation of GSR Positive_regulation of HDAC1 1 0.10 0.69 0.25 5.00
189 INT262229 Binding of CYP3A4 and Casr 1 0.03 0.37 0.24 5.00
190 INT261394 Nsdhl Negative_regulation of nt 1 0.01 1.69 0.24 5.00
191 INT262179 Nr1i2 Regulation of Gene_expression of Nr0b2 1 0.09 0.07 0.24 5.00
192 INT262211 Nr1h4 Negative_regulation of Gene_expression of Cyp7a1 1 0.09 0.14 0.23 5.00
193 INT271001 Binding of PTGER2 and Aia1 1 0.00 1.28 0.23 5.00
194 INT262159 Positive_regulation of Nr1h4 Negative_regulation of Gene_expression of Cyp7a1 1 0.09 0.14 0.23 5.00
195 INT173120 Binding of PPARA and NR1H4 8 0.09 2.79 0.23 5.00
196 INT262151 Vdr Regulation of Cyp24a1 1 0.24 0.24 0.23 5.00
197 INT261389 Nsdhl Positive_regulation of Esr2 1 0.06 1.04 0.23 5.00
198 INT348321 Binding of POMC and ASPM 1 0.02 0.39 0.23 5.00
199 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22 5.00
200 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Adverse Drug Reaction. They are ordered first by their pain relevance and then by number of times they were reported in Adverse Drug Reaction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT9429 Positive_regulation of Clcn1 18 0.58 10.03 2.07 100.00
2 INT16178 Gene_expression of Clcn1 20 0.69 8.67 1.46 100.00
3 INT109964 Binding of AKR1B1 4 0.31 3.95 0.7 100.00
4 INT260501 Positive_regulation of AKR1B1 5 0.67 4.31 0.71 100.00
5 INT37012 Binding of Clcn1 11 0.33 4.83 0.7 100.00
6 INT11699 Binding of HLA-E 85 0.47 52.51 13.41 100.00
7 INT23834 Negative_regulation of AKR1B1 8 0.55 3.79 1.15 100.00
8 INT5205 Localization of AR 43 0.80 12.87 4.63 100.00
9 INT275146 Regulation of JMY 1 0.00 0.67 0.04 100.00
10 INT235683 Regulation of Clcn1 4 0.21 1.49 0.03 100.00
11 INT939 Gene_expression of PAEP 86 0.77 31.02 8.59 100.00
12 INT187422 Negative_regulation of MTTP 23 0.57 11.75 0.24 100.00
13 INT145594 Gene_expression of Mtx1 64 0.57 35.33 30.35 99.98
14 INT180626 Gene_expression of spc 6 0.34 6.83 0.15 99.90
15 INT7743 Binding of Hrh2 19 0.47 7.75 7.11 99.90
16 INT14598 Gene_expression of Tpsab1 40 0.73 14.55 5.4 99.84
17 INT5539 Negative_regulation of Mme 75 0.59 28.91 41.84 99.84
18 INT2416 Negative_regulation of MAOA 92 0.59 42.24 36.5 99.82
19 INT114741 Binding of PRB1 19 0.36 5.44 1 99.80
20 INT241610 Binding of Tcam1 1 0.28 5.31 1.67 99.80
21 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 99.76
22 INT76427 Regulation of Negative_regulation of Cpox 17 0.31 6.75 7.93 99.76
23 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 99.74
24 INT55944 Positive_regulation of Cpox 214 0.57 105.14 81.4 99.70
25 INT66819 Binding of CYP2C9 41 0.48 8.23 8.76 99.44
26 INT35548 Regulation of Mme 9 0.45 10.62 2.97 99.44
27 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.38
28 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 99.36
29 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 99.34
30 INT16405 Regulation of CD8A 38 0.45 19.04 5.31 99.32
31 INT17747 Regulation of Cd4 14 0.41 10.02 2.12 99.32
32 INT47914 Regulation of Il2ra 5 0.18 3.05 1.86 99.32
33 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 99.22
34 INT178547 Gene_expression of CSTB 9 0.29 6.53 0.18 99.20
35 INT178535 Regulation of Gene_expression of CSTB 2 0.19 2.91 0.06 99.20
36 INT8775 Binding of IGHE 167 0.48 102.61 23.54 99.20
37 INT194533 Binding of UOX 2 0.47 3.86 0.2 99.20
38 INT50657 Positive_regulation of HTR2B 8 0.67 3.95 4.71 99.14
39 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 99.04
40 INT135306 Binding of CYP2C8 10 0.46 4.37 0.46 99.04
41 INT45717 Gene_expression of Yif1 3 0.52 3.22 0.27 98.96
42 INT76048 Regulation of IGKV1D-42 1 0.01 1.08 0.09 98.96
43 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 98.84
44 INT57922 Gene_expression of CYP2C9 65 0.78 22.24 7.53 98.84
45 INT156100 Gene_expression of AKR1B1 4 0.65 3.64 0.41 98.76
46 INT5401 Gene_expression of DBH 17 0.78 1.92 8.01 98.76
47 INT156820 Negative_regulation of Coq10a 2 0.15 1.49 0 98.74
48 INT192449 Binding of CLTC 5 0.23 3.57 0.09 98.74
49 INT221496 Localization of ISCA1 4 0.73 2.12 0.23 98.72
50 INT8476 Binding of Bche 10 0.37 4.38 1.29 98.68
51 INT11203 Gene_expression of BCR 30 0.75 33.49 1.22 98.64
52 INT258759 Regulation of Localization of ADHD1 3 0.38 4.71 0.32 98.44
53 INT701 Localization of IGHE 87 0.80 40.5 10.62 98.40
54 INT12992 Negative_regulation of Gene_expression of Ptgs1 33 0.42 20.47 11.77 98.40
55 INT177600 Gene_expression of C7orf49 21 0.52 7.1 6.92 98.36
56 INT18654 Gene_expression of HRH2 9 0.67 5.73 2.19 98.30
57 INT10796 Gene_expression of CYP2B6 131 0.77 30.14 35.27 98.28
58 INT93859 Negative_regulation of Srl 1 0.37 0.55 0.8 98.20
59 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 98.18
60 INT3286 Positive_regulation of Gpt 90 0.69 45.08 28.34 98.16
61 INT32706 Gene_expression of Cyp3a23/3a1 51 0.65 19.48 15.06 98.16
62 INT205651 Localization of FUS 4 0.36 4.15 0.31 98.16
63 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58 98.16
64 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 97.98
65 INT219848 Positive_regulation of Oas1b 3 0.63 5.32 0.43 97.98
66 INT188255 Gene_expression of DKK1 19 0.60 12.69 2.39 97.94
67 INT212293 Gene_expression of Vsnl1 14 0.29 8.1 0.61 97.92
68 INT14477 Positive_regulation of TPSAB1 10 0.69 5.88 1.46 97.88
69 INT215975 Regulation of HPT 3 0.26 2.75 0.66 97.84
70 INT76049 Regulation of CALB1 2 0.07 1.58 0.32 97.84
71 INT18191 Negative_regulation of Cyp3a23/3a1 48 0.57 10.21 13.38 97.76
72 INT113684 Negative_regulation of Gene_expression of Cyp3a23/3a1 5 0.36 2.04 1.71 97.76
73 INT9556 Negative_regulation of NAV1 47 0.59 28.49 49.33 97.72
74 INT2039 Regulation of CYP2B6 30 0.60 7.75 6.43 97.72
75 INT3060 Negative_regulation of Bche 94 0.59 46.75 18.51 97.68
76 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 97.56
77 INT114501 Transcription of MCPH1 4 0.43 0.71 0.79 97.52
78 INT76127 Transcription of CEL 5 0.71 2.02 0.7 97.52
79 INT114496 Transcription of Tpsab1 1 0.02 0.35 0.1 97.52
80 INT114500 Transcription of SPG21 1 0.52 0.35 0.1 97.52
81 INT34644 Binding of HLA-C 19 0.47 9.41 2.2 97.40
82 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95 97.38
83 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 97.36
84 INT69992 Negative_regulation of Hmox2 93 0.50 49.01 44.07 97.36
85 INT36173 Positive_regulation of Gs 17 0.43 7.48 8.19 97.36
86 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06 97.34
87 INT228916 Transcription of spc 2 0.30 1.62 0.18 97.32
88 INT17312 Binding of HSPG2 30 0.41 33.01 4.88 97.20
89 INT240359 Binding of Tnc 2 0.35 11.67 1.48 97.20
90 INT41721 Negative_regulation of MTOR 40 0.58 32.49 2.83 97.20
91 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 97.14
92 INT157720 Localization of ADHD1 15 0.64 15.84 1.69 97.14
93 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 97.08
94 INT13543 Positive_regulation of LTC4S 5 0.58 2.26 0.88 97.08
95 INT105923 Binding of FUT1 34 0.14 17.81 4.79 97.00
96 INT36619 Gene_expression of SOCS1 9 0.44 4.83 0.55 96.92
97 INT289983 Regulation of Positive_regulation of Narf 1 0.01 1.12 0.46 96.92
98 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 96.88
99 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 96.88
100 INT188252 Positive_regulation of DKK1 4 0.41 2.94 0.08 96.80
101 INT817 Negative_regulation of Abp1 15 0.49 4.25 3.56 96.72
102 INT66651 Negative_regulation of SLC45A2 3 0.57 1.31 1.12 96.64
103 INT245105 Binding of Axin1 2 0.06 0.65 0 96.64
104 INT17313 Positive_regulation of HSPG2 57 0.67 55.78 16.65 96.62
105 INT7339 Localization of CALM1 46 0.75 16.15 16.47 96.60
106 INT260500 Positive_regulation of Positive_regulation of AKR1B1 1 0.19 0.47 0 96.58
107 INT5759 Positive_regulation of Ptgs1 127 0.69 53.45 53.04 96.48
108 INT202940 Binding of AMD1 13 0.41 16.43 0.56 96.48
109 INT1646 Negative_regulation of Localization of FSHR 17 0.58 7.36 3.46 96.44
110 INT1642 Negative_regulation of Localization of PLOD1 40 0.58 10.67 17.95 96.44
111 INT16015 Negative_regulation of Localization of LHB 10 0.37 2.95 2.9 96.44
112 INT76860 Gene_expression of HSPG2 32 0.65 37.14 9.06 96.40
113 INT44540 Binding of GPT 3 0.36 6.14 0.23 96.40
114 INT194298 Gene_expression of DHPS 1 0.62 8.84 0.37 96.36
115 INT69564 Binding of Cyp3a23/3a1 11 0.34 4.67 3.2 96.32
116 INT1539 Positive_regulation of MSMB 22 0.69 9.42 4.62 96.28
117 INT78190 Gene_expression of Tnc 10 0.75 21.23 2.91 96.28
118 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 96.28
119 INT157932 Positive_regulation of ADHD1 46 0.48 52.18 6.13 96.14
120 INT265958 Binding of Abra 1 0.04 1.32 0.22 96.08
121 INT98392 Positive_regulation of Spt 6 0.39 2.35 0.54 96.04
122 INT6097 Negative_regulation of NEUROD1 30 0.57 9.71 6.24 95.96
123 INT5372 Localization of LHB 55 0.68 9.47 19 95.96
124 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 95.92
125 INT289989 Positive_regulation of Narf 1 0.02 3.85 0.73 95.92
126 INT91703 Negative_regulation of Myoz1 78 0.58 53.78 13.5 95.88
127 INT88245 Gene_expression of Slc11a1 42 0.53 18.86 6.2 95.88
128 INT13607 Binding of Ack 11 0.36 5.77 6.01 95.84
129 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 95.76
130 INT3593 Gene_expression of ADRA1D 70 0.75 29.48 20.87 95.58
131 INT158672 Positive_regulation of Calm1 10 0.44 4.79 5.86 95.40
132 INT11823 Positive_regulation of GGT1 53 0.67 45.84 7.55 95.36
133 INT24889 Negative_regulation of CABIN1 36 0.48 16.76 4.73 95.36
134 INT269746 Positive_regulation of Localization of AMD1 1 0.43 2.54 0 95.24
135 INT197171 Negative_regulation of Binding of Ppara 15 0.43 11.51 4.41 95.16
136 INT122041 Binding of Ppara 308 0.48 189.17 51.48 95.16
137 INT920 Localization of PLOD1 223 0.81 42.25 78.7 95.12
138 INT9349 Gene_expression of BBS2 15 0.49 12.77 4.22 95.08
139 INT47859 Negative_regulation of Cyp2e1 41 0.59 16.92 21.72 95.04
140 INT4419 Gene_expression of GOT1 20 0.65 22.53 2.53 95.04
141 INT105921 Localization of FUT1 13 0.23 3.92 1.39 95.04
142 INT165840 Gene_expression of GSTZ1 3 0.37 2.71 0.41 95.00
143 INT32515 Negative_regulation of B4GALNT1 82 0.43 28.1 17.46 94.96
144 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 94.88
145 INT255017 Gene_expression of Got2 3 0.65 0.33 0 94.88
146 INT14701 Negative_regulation of IFNA1 118 0.54 84.19 20.08 94.88
147 INT504 Gene_expression of GPT 42 0.75 27.54 3.99 94.88
148 INT78995 Negative_regulation of Agtr2 26 0.42 13.05 4.56 94.84
149 INT269750 Localization of AMD1 2 0.64 2.82 0.13 94.84
150 INT912 Localization of FSHR 91 0.79 23.61 15.58 94.80
151 INT186593 Gene_expression of SFRP5 1 0.16 3.94 0.46 94.80
152 INT186598 Binding of SFRP5 1 0.07 0.92 0.21 94.80
153 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08 94.76
154 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81 94.72
155 INT97 Negative_regulation of Adrb1 102 0.59 32.44 26.9 94.68
156 INT14597 Negative_regulation of Tpsab1 5 0.37 1.52 1.59 94.68
157 INT10763 Localization of IL2 157 0.80 81.11 33.21 94.56
158 INT79441 Localization of XCL1 5 0.62 3.98 2 94.56
159 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 94.52
160 INT354785 Regulation of Binding of Tnc 1 0.06 1.63 0.53 94.48
161 INT354787 Regulation of Binding of HSPG2 1 0.23 1.63 0.53 94.48
162 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58 94.48
163 INT546 Binding of ALB 311 0.48 85.98 60.14 94.44
164 INT24643 Gene_expression of Hdlcl1 30 0.73 26.83 1.9 94.44
165 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 94.40
166 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 94.32
167 INT88987 Gene_expression of HMGA2 8 0.77 10.46 0.64 94.32
168 INT113104 Gene_expression of SCFV 18 0.65 7.13 1.2 94.28
169 INT186601 Negative_regulation of SCFV 2 0.14 1.38 0.41 94.28
170 INT24978 Binding of SFTPA1 22 0.47 15.09 7.76 94.20
171 INT116362 Positive_regulation of C4A 17 0.69 11.53 1.03 94.16
172 INT9055 Positive_regulation of Cog1 22 0.68 14.08 2.95 94.08
173 INT33008 Gene_expression of Dync1h1 41 0.68 23.85 3.82 94.04
174 INT1976 Regulation of Gene_expression of Prl 80 0.62 20.19 36 93.96
175 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 93.92
176 INT37080 Negative_regulation of OAS2 4 0.05 1.3 0.89 93.84
177 INT275142 Negative_regulation of Binding of CSTB 1 0.04 0.66 0.03 93.80
178 INT275147 Binding of CSTB 2 0.04 0.94 0.03 93.80
179 INT272462 Transcription of Clcn1 4 0.63 1.21 0 93.80
180 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 93.72
181 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 93.68
182 INT135920 Binding of SRY 9 0.45 3.57 1.45 93.68
183 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 93.60
184 INT169475 Localization of HRAS 14 0.73 9.02 3.9 93.60
185 INT6323 Positive_regulation of Gabrg1 213 0.70 45.08 124.34 93.56
186 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 93.44
187 INT89 Positive_regulation of Gast 187 0.70 80.49 42.07 93.44
188 INT1982 Regulation of NARFL 119 0.49 116.2 14.35 93.36
189 INT24644 Regulation of Hdlcl1 18 0.42 15.44 0.91 93.36
190 INT67597 Negative_regulation of Das 17 0.37 9.95 5.05 93.32
191 INT141002 Negative_regulation of Fcer2a 15 0.12 7.17 1.88 93.28
192 INT55367 Localization of Dbp 18 0.70 7.43 0.38 92.96
193 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 92.88
194 INT16234 Positive_regulation of CFH 25 0.50 26.05 3.33 92.88
195 INT25170 Positive_regulation of Localization of Car2 78 0.67 15.25 11.24 92.64
196 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35 92.64
197 INT37057 Gene_expression of Tlx2 12 0.76 7.98 2.38 92.64
198 INT170503 Positive_regulation of Localization of Tmie 11 0.29 3.27 0.61 92.64
199 INT53949 Positive_regulation of Gene_expression of Cpox 82 0.65 38.12 25.93 92.60
200 INT64386 Binding of Cyp11a1 13 0.46 5.09 3.01 92.52
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