D:Affective Disorder

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Disease Term
Synonyms Affect Disorder, Affective Disorders, Affective Equivalents, Affective Neurosis, Cyclothymia, DISORDER AFFECTIVE, DISORDER MOOD, Disorders Affective, Disorders Mood, Dysthymia, Elation
Documents 1706
Hot Single Events 200
Hot Interactions 11

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Affective Disorder. They are ordered first by their relevance to Affective Disorder and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT21413 Binding of SGCG and Srms 1 0.00 0.2 0.23 100.00
2 INT21412 Binding of Maoa and Srms 1 0.00 0.2 0.23 100.00
3 INT217074 Binding of Acsm3 and Axin1 1 0.00 5.37 0.17 99.68
4 INT321479 Ubqln1 Regulation of Cfp 1 0.00 0.37 0.67 99.56
5 INT129313 HTR2A Positive_regulation of Oxt 1 0.41 0.22 0.67 99.20
6 INT349131 Binding of Ltp and Cfp 1 0.04 1.08 0.3 89.28
7 INT115597 Avp Positive_regulation of Crh 1 0.56 0.79 0.31 89.12
8 INT66535 Binding of Pnoc and Oprl1 43 0.54 5.93 32.4 87.60
9 INT80787 Negative_regulation of Binding of Pnoc and Oprl1 2 0.39 0.39 1.72 83.60
10 INT304578 Negative_regulation of HDAC9 Positive_regulation of Gene_expression of Bdnf 1 0.06 0.9 0.49 81.84
11 INT235870 Bdnf Regulation of Gene_expression of Slc6a4 1 0.09 0.77 0.5 80.16
12 INT317705 Gad2 Regulation of Gene_expression of Gabrg1 1 0.28 0.53 0.8 79.60
13 INT235885 Prkca Negative_regulation of Slc6a4 1 0.05 0.14 0.49 78.88
14 INT262185 Positive_regulation of Binding of Ncoa1 and Nr1i2 1 0.04 0.56 0.12 76.40
15 INT262146 Binding of Ncoa1 and Nr1i2 1 0.03 0.56 0.11 76.08
16 INT287890 THEMIS Regulation of Gene_expression of EPHB2 1 0.00 0.87 0.14 73.48
17 INT287883 FOS Regulation of Gene_expression of EPHB2 1 0.01 0.87 0.14 73.48
18 INT217075 Binding of Acsm3 and Slc26a4 1 0.04 2.11 0.04 72.80
19 INT298456 Prkaca Positive_regulation of Phosphorylation of Adarb1 1 0.00 1.86 2.85 72.24
20 INT30575 SST Negative_regulation of Localization of Pomc 1 0.00 0.71 1.06 70.04
21 INT271194 Binding of Bdnf and Gopc 1 0.03 0.49 0.6 69.36
22 INT271192 Binding of Gopc and Gtf3a 1 0.00 0.49 0.6 69.36
23 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34 66.96
24 INT189151 MTNR1B Positive_regulation of Gene_expression of IL6 1 0.01 0.35 0.47 66.88
25 INT189145 MTNR1B Positive_regulation of Gene_expression of IL2 1 0.02 0.3 0.26 66.88
26 INT189142 MTNR1B Positive_regulation of Gene_expression of IL12A 1 0.01 0.29 0.24 66.88
27 INT41659 IL31RA Regulation of PRL 1 0.22 1.07 0.98 66.72
28 INT41658 IL31RA Regulation of GH1 1 0.09 1.07 0.98 66.72
29 INT341426 EPO Regulation of NGF 1 0.51 0.5 0.47 66.72
30 INT341425 EPO Regulation of BDNF 1 0.51 0.5 0.47 66.32
31 INT5451 CRH Regulation of POMC 2 0.28 0.39 0.85 64.84
32 INT235875 Bdnf Positive_regulation of Phosphorylation of Mapk1 1 0.09 0.38 0.17 64.36
33 INT152164 Binding of GALR3 and GAL 2 0.31 0.88 0.39 63.76
34 INT235880 Binding of Mtap2 and Prkaca 1 0.07 0.41 0.38 62.76
35 INT78348 Binding of GALR1 and GAL 4 0.41 1.47 0.8 62.64
36 INT207211 Binding of Creb1 and Crem 2 0.30 1.35 0.36 62.56
37 INT323346 Positive_regulation of Tyrp1 Positive_regulation of Positive_regulation of Gpr35 1 0.11 0.76 0.21 59.28
38 INT190652 Mdk Positive_regulation of Phosphorylation of Mapk1 2 0.50 0.85 0.33 57.68
39 INT235884 Htr3a Regulation of Nr3c1 1 0.00 0.63 0.32 56.04
40 INT41657 IL31RA Positive_regulation of CSF2 1 0.22 0.4 0.41 53.20
41 INT258765 Lmo1 Regulation of ADHD1 1 0.05 1.98 0.09 52.72
42 INT183176 Binding of FGFR2 and NUDT6 1 0.05 1.07 0.84 52.00
43 INT183177 Binding of FGFR3 and NUDT6 1 0.06 1.08 0.84 52.00
44 INT183175 Binding of FGF2 and NUDT6 1 0.07 1.07 0.84 52.00
45 INT283980 Binding of IL12A and IL23A 2 0.24 1.33 0.57 51.16
46 INT258763 Binding of Drd5 and ADHD1 1 0.07 1.11 0.31 50.68
47 INT258764 Binding of Drd4 and ADHD1 1 0.08 1.11 0.31 50.68
48 INT258758 Binding of Drd4 and Lmo1 1 0.04 0.64 0.08 50.68
49 INT258756 Binding of Drd5 and Lmo1 1 0.03 0.64 0.08 50.68
50 INT272977 Osr1 Regulation of ADHD1 1 0.01 1.79 0 48.88
51 INT38936 Binding of Avp and Crh 7 0.40 0.82 1.04 48.40
52 INT342647 Negative_regulation of Binding of Avp and Crh 1 0.37 0.64 0.18 48.40
53 INT341428 EPO Positive_regulation of NGF 1 0.52 0.37 0.48 47.52
54 INT272978 Binding of Osr1 and ADHD1 1 0.00 1.91 0 47.12
55 INT354062 Avp Regulation of Lyz2 1 0.00 0.12 0.38 46.48
56 INT341427 EPO Positive_regulation of BDNF 1 0.52 0.36 0.48 45.60
57 INT304577 Binding of Arntl and Clock Regulation of Gene_expression of Maoa 1 0.01 0.3 0.44 45.12
58 INT190987 Abat Regulation of Scn2a1 1 0.03 0.07 0.59 43.80
59 INT304576 Binding of Arntl and Clock 6 0.37 0.43 0.5 42.68
60 INT235876 Hspg2 Positive_regulation of Prkca 1 0.03 0.23 0.53 38.16
61 INT315333 Binding of Cflar and Fadd 1 0.01 0.49 0.42 36.48
62 INT341777 SLC6A4 Regulation of EPHB1 1 0.02 0.96 0.3 34.64
63 INT298454 Prkcg Positive_regulation of Phosphorylation of Adarb1 1 0.00 0.41 1.19 30.36
64 INT149473 Avp Positive_regulation of Localization of Pomc 4 0.48 2.64 0.56 27.28
65 INT304575 Creb1 Regulation of Gene_expression of Bdnf 1 0.04 1 0.84 26.24
66 INT129919 IFNA2 Positive_regulation of Gene_expression of SLC6A4 1 0.02 0.38 0.69 25.00
67 INT129921 IL4 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.38 0.68 25.00
68 INT129920 IFNA2 Regulation of ADO 1 0.00 0.64 0.64 25.00
69 INT355687 Art2b Positive_regulation of Gene_expression of Mc3r 1 0.02 1.01 0.48 22.96
70 INT323345 Ido1 Positive_regulation of Gene_expression of Tlr4 1 0.14 0.69 0.13 21.00
71 INT258757 Binding of Drd2 and Rends1 1 0.00 1.26 0.25 20.44
72 INT317704 Binding of Gabrg1 and Tst 1 0.20 0.37 0.24 12.76
73 INT321476 Binding of Slc6a3 and Slc6a2 1 0.01 0.41 1.14 12.64
74 INT321473 Binding of Slc6a3 and Ubqln1 1 0.00 0.41 1.13 12.64
75 INT321477 Binding of Ubqln1 and Flvcr2 1 0.00 0.81 2.26 12.24
76 INT321478 Binding of Slc6a2 and Flvcr2 1 0.00 0.41 1.14 12.24
77 INT190988 Vip Positive_regulation of Gene_expression of Scn2a1 1 0.16 0.1 0.57 11.72
78 INT321474 Binding of Slc6a2 and Ubqln1 1 0.00 0.8 2.27 11.28
79 INT287891 Binding of CDH1 and KRT20 1 0.00 0.5 0 10.28
80 INT155009 IL23A Positive_regulation of Gene_expression of IL17A 2 0.17 0.62 0.39 8.48
81 INT325313 IL23A Positive_regulation of Gene_expression of IL22 1 0.20 0.48 0.23 8.48
82 INT263359 Dlat Negative_regulation of Gars 1 0.15 0.31 0.35 7.20
83 INT295292 Jun Positive_regulation of Transcription of Nos2 1 0.01 0 0 6.08
84 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 5.00
85 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25 5.00
86 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 5.00
87 INT289979 Binding of Helt and Negative_regulation of Maoa 1 0.00 0.17 3.14 5.00
88 INT152699 Bdnf Positive_regulation of Ltp 5 0.05 1.22 2.95 5.00
89 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78 5.00
90 INT284088 Binding of BDNF and NTRK2 5 0.41 3.4 2.37 5.00
91 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99 5.00
92 INT97208 Binding of Gabrg1 and Gabbr1 2 0.07 0.31 1.94 5.00
93 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
94 INT190981 Binding of Npy and Scn2a1 1 0.10 0 1.75 5.00
95 INT209087 Crh Positive_regulation of Ceacam3 1 0.24 1.45 1.54 5.00
96 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48 5.00
97 INT298458 Binding of Calcrl and Adarb1 1 0.00 0.23 1.41 5.00
98 INT298455 Calca Positive_regulation of Gene_expression of Ceacam3 1 0.17 0.47 1.34 5.00
99 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33 5.00
100 INT262377 Binding of Comt and Fmod 1 0.06 1.47 1.29 5.00
101 INT280480 Binding of Bdnf and Ngfr 5 0.25 3.14 1.27 5.00
102 INT352269 Binding of Jund and Adora1 1 0.15 1.2 1.25 5.00
103 INT210982 Binding of Cnr1 and Cfp 2 0.22 1.27 1.2 5.00
104 INT321475 Slc6a2 Positive_regulation of Ubqln1 1 0.00 0.38 1.19 5.00
105 INT222516 Binding of Calcrl and Ramp1 5 0.17 0.11 1.12 5.00
106 INT196812 Ppp1r1b Negative_regulation of Ppp1cc 3 0.07 0.13 1.12 5.00
107 INT209088 Binding of Ceacam3 and Crhr1 1 0.34 1.26 1.11 5.00
108 INT338894 TNFSF14 Negative_regulation of Gsk3a 1 0.00 0.54 1.04 5.00
109 INT224856 Binding of Bdnf and Eef2 1 0.14 0 1.02 5.00
110 INT338892 TNFSF14 Regulation of Abat 1 0.00 0.61 1.01 5.00
111 INT338895 TNFSF14 Regulation of Regulation of Abat 1 0.00 0.62 1.01 5.00
112 INT81127 Binding of Gabrd and Abat 3 0.25 0 0.96 5.00
113 INT36683 Gh1 Regulation of Gnrhr 3 0.08 1.25 0.95 5.00
114 INT206857 Binding of Calca and Calcrl 4 0.37 1.9 0.95 5.00
115 INT338893 TNFSF14 Positive_regulation of Gene_expression of Gria1 1 0.07 0.59 0.94 5.00
116 INT262165 Nr0b2 Negative_regulation of Nr5a2 1 0.02 0.5 0.92 5.00
117 INT44442 GNRH1 Positive_regulation of Localization of PLOD1 3 0.50 0.78 0.86 5.00
118 INT113542 Binding of Calca and Adarb1 2 0.00 0.44 0.85 5.00
119 INT122191 Binding of Crh and Ucn 4 0.36 0.79 0.82 5.00
120 INT190868 Binding of Marcks and Ltp 1 0.01 0.87 0.81 5.00
121 INT190869 Binding of Prkca and Ltp 1 0.03 0.86 0.81 5.00
122 INT271193 Creb1 Regulation of Bdnf 1 0.15 0.28 0.81 5.00
123 INT298457 Binding of Calca and Npr1 1 0.01 0.39 0.77 5.00
124 INT190867 Binding of Marcks and Prkca 1 0.17 0.8 0.77 5.00
125 INT243024 Binding of Dcpp1 and Slc6a4 1 0.08 0.42 0.76 5.00
126 INT243025 Dcpp1 Regulation of Slc6a4 1 0.10 0.43 0.76 5.00
127 INT292598 CNR1 Regulation of ABAT 1 0.08 0.32 0.75 5.00
128 INT292599 CNR1 Regulation of Localization of ABAT 1 0.08 0.32 0.75 5.00
129 INT190986 Per1 Positive_regulation of Scn2a1 1 0.17 0 0.74 5.00
130 INT190979 Per2 Positive_regulation of Scn2a1 1 0.20 0 0.74 5.00
131 INT235604 Binding of Htr1a and Htr3a 1 0.01 0 0.74 5.00
132 INT190984 Binding of Scn2a1 and Gria1 1 0.03 0.08 0.71 5.00
133 INT261378 Nsdhl Negative_regulation of Gene_expression of Flvcr2 1 0.01 0.34 0.7 5.00
134 INT224892 Bdnf Regulation of Localization of Ltp 1 0.03 0.17 0.69 5.00
135 INT224893 Bdnf Regulation of Ltp 1 0.03 0.17 0.69 5.00
136 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67 5.00
137 INT122190 Binding of Crhr1 and Ucn 4 0.49 0.65 0.67 5.00
138 INT33561 Crh Positive_regulation of POMC 3 0.45 1.19 0.64 5.00
139 INT235881 Prkaca Positive_regulation of Creb1 2 0.10 0.16 0.64 5.00
140 INT202160 Binding of ARSD and CSF1R 1 0.16 1.69 0.59 5.00
141 INT192873 Binding of RS1 and Nktcn1 1 0.00 0.8 0.59 5.00
142 INT261372 Gsk3b Regulation of Gene_expression of Ifi205 1 0.00 0.24 0.58 5.00
143 INT223928 Cux1 Regulation of Gene_expression of Maoa 1 0.24 0.15 0.57 5.00
144 INT223924 Cux1 Regulation of Gene_expression of Serpina1 1 0.04 0.15 0.57 5.00
145 INT290594 BDNF Positive_regulation of Localization of S100B 1 0.08 0.6 0.57 5.00
146 INT93063 Binding of gr and Jun 3 0.14 0.79 0.57 5.00
147 INT352270 Tnf Positive_regulation of GZMA 1 0.13 2.43 0.55 5.00
148 INT202157 Binding of CSF1R and SLC6A4 1 0.08 0.9 0.54 5.00
149 INT352268 Tnf Positive_regulation of Arl6ip6 1 0.02 2.42 0.54 5.00
150 INT298462 Calca Regulation of PPR 1 0.03 0 0.54 5.00
151 INT223934 HSPG2 Negative_regulation of Gene_expression of Cux1 1 0.03 0 0.53 5.00
152 INT184878 Binding of Lmo1 and ADHD1 2 0.04 2.33 0.53 5.00
153 INT310532 IL6 Regulation of Regulation of TNF 1 0.34 0.73 0.52 5.00
154 INT310531 IL6 Regulation of Regulation of ADIPOQ 1 0.19 0.73 0.52 5.00
155 INT349130 Phosphorylation of Gria1 Positive_regulation of Shisa9 1 0.00 0.49 0.52 5.00
156 INT117203 Binding of IL1B and IL6 2 0.20 1.4 0.51 5.00
157 INT223925 Drd1a Positive_regulation of Gene_expression of Serpina1 1 0.01 0 0.51 5.00
158 INT205733 Gphn Regulation of Gene_expression of Gabrd 1 0.03 0.18 0.51 5.00
159 INT271191 Bdnf Regulation of Slc6a4 1 0.03 0.29 0.51 5.00
160 INT224853 Binding of Bdnf and Eif4e 1 0.10 0 0.5 5.00
161 INT228449 PMAIP1 Negative_regulation of Fgf2 1 0.00 0.07 0.49 5.00
162 INT228448 PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49 5.00
163 INT339275 Il6 Regulation of KRT20 1 0.00 3.11 0.49 5.00
164 INT228447 Negative_regulation of PMAIP1 Negative_regulation of Cntf 1 0.00 0.07 0.49 5.00
165 INT320451 ECT Positive_regulation of Gene_expression of BDNF 1 0.05 1.21 0.49 5.00
166 INT36684 Gh1 Regulation of Prl 2 0.18 1.25 0.48 5.00
167 INT189859 Binding of SLC6A3 and ADHD1 2 0.32 0.68 0.48 5.00
168 INT132792 IL4 Positive_regulation of IL6 4 0.28 1.81 0.47 5.00
169 INT280826 Il6 Positive_regulation of Localization of Avp 1 0.01 0.64 0.47 5.00
170 INT235882 Creb1 Positive_regulation of Positive_regulation of Bdnf 1 0.11 0.17 0.47 5.00
171 INT223936 HSPG2 Positive_regulation of Gene_expression of Cux1 1 0.03 0 0.46 5.00
172 INT334180 Tdo2 Negative_regulation of Tbpl1 1 0.10 0.16 0.45 5.00
173 INT237452 Binding of STAR and CHTF8 1 0.00 0.48 0.45 5.00
174 INT218783 Binding of Faah and Cfp 1 0.04 0.55 0.45 5.00
175 INT223935 HSPG2 Positive_regulation of Cux1 1 0.03 0 0.45 5.00
176 INT262155 Nr5a2 Positive_regulation of Cyp7a1 1 0.07 0.24 0.45 5.00
177 INT190870 BDNF Positive_regulation of Phosphorylation of Mapk1 1 0.12 0.54 0.44 5.00
178 INT262220 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Abcc2 1 0.14 0.25 0.44 5.00
179 INT189197 RASGRP1 Positive_regulation of JUN 1 0.07 1.26 0.43 5.00
180 INT325391 Binding of Ghrl and Ghsr 2 0.17 0.14 0.43 5.00
181 INT189154 MTNR1B Positive_regulation of Gene_expression of IFNG 1 0.01 0.06 0.43 5.00
182 INT237453 Binding of STAR and MESP1 1 0.00 0.47 0.42 5.00
183 INT138384 Binding of Htr1b and ADHD1 2 0.07 1.46 0.42 5.00
184 INT308696 Binding of Tlr4 and Tlr4 1 0.00 0.34 0.42 5.00
185 INT327562 Binding of MCS and AKR1B10 1 0.00 0.5 0.41 5.00
186 INT261374 Nsdhl Regulation of Esr2 1 0.05 0.76 0.41 5.00
187 INT261370 Nsdhl Regulation of Esr1 1 0.01 0.75 0.41 5.00
188 INT224894 Bdnf Positive_regulation of Positive_regulation of IER3 1 0.00 0.36 0.41 5.00
189 INT190977 Npy Regulation of Scn2a1 1 0.16 0 0.4 5.00
190 INT235868 Creb1 Negative_regulation of Atf6b 1 0.02 0.21 0.4 5.00
191 INT237454 Binding of STAR and GREM1 1 0.00 0.44 0.4 5.00
192 INT262186 Nr0b2 Positive_regulation of Negative_regulation of Cyp7a1 1 0.12 0.28 0.4 5.00
193 INT240618 Binding of INS and ADIPOQ 3 0.17 2.54 0.4 5.00
194 INT188336 IL6 Positive_regulation of Localization of POMC 1 0.01 0.83 0.4 5.00
195 INT235887 CALM1 Regulation of Akap5 1 0.00 0 0.39 5.00
196 INT235860 Prkca Regulation of Akap5 1 0.16 0 0.39 5.00
197 INT262205 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Cyp3a11 1 0.33 0.11 0.38 5.00
198 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38 5.00
199 INT288545 Gsk3b Negative_regulation of gr 1 0.25 0.38 0.38 5.00
200 INT262153 Binding of Clta and Nr1i2 1 0.05 0.65 0.38 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Affective Disorder. They are ordered first by their pain relevance and then by number of times they were reported in Affective Disorder. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1 100.00
2 INT104441 Binding of NOVA2 72 0.42 16.41 10.51 100.00
3 INT70065 Regulation of MAFD1 1 0.00 1.23 0.79 100.00
4 INT212498 Gene_expression of USP39 2 0.51 1.84 0.32 100.00
5 INT212499 Binding of USP39 1 0.28 0.67 0 100.00
6 INT212497 Regulation of USP39 1 0.34 0.82 0.13 100.00
7 INT243198 Gene_expression of ZNRF1 2 0.09 4.05 0.09 100.00
8 INT189233 Regulation of NPAS2 1 0.08 0.47 0 100.00
9 INT7234 Binding of GNRH1 43 0.47 21.59 12.36 99.98
10 INT135373 Regulation of Gsk3b 35 0.62 18.11 3.53 99.96
11 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9 99.92
12 INT2140 Regulation of REN 104 0.62 28.24 24.49 99.84
13 INT290793 Negative_regulation of Clock 6 0.39 1.48 0.09 99.84
14 INT54924 Gene_expression of RLS 67 0.62 83.2 14.25 99.80
15 INT57368 Regulation of ADHD1 39 0.50 42.23 5.01 99.72
16 INT181589 Binding of OPN1SW 13 0.32 9.47 4.07 99.70
17 INT8380 Positive_regulation of Gene_expression of Npy 49 0.70 19.62 24.13 99.68
18 INT7956 Regulation of Gene_expression of Th 44 0.61 8.26 29.31 99.66
19 INT5452 Regulation of CRH 56 0.62 15.32 12.42 99.64
20 INT28728 Regulation of Cfp 49 0.46 13.15 21.43 99.56
21 INT152433 Binding of CSF1R 6 0.33 10.97 5.54 99.52
22 INT177993 Localization of CSF1R 4 0.73 7.49 2.94 99.52
23 INT181260 Regulation of Slc26a4 2 0.30 1.67 0.03 99.52
24 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51 99.48
25 INT75742 Binding of RLS 86 0.42 95.27 19.04 99.44
26 INT1562 Localization of Crh 499 0.81 126.74 236.68 99.40
27 INT4740 Gene_expression of Th 298 0.78 61.27 154.03 99.38
28 INT6108 Gene_expression of Npy 292 0.78 110.65 148.21 99.38
29 INT140497 Positive_regulation of NALCN 4 0.31 1.03 1 99.32
30 INT118107 Positive_regulation of Avpr1b 4 0.66 6.89 2.99 99.24
31 INT217072 Negative_regulation of Acsm3 5 0.29 6.15 1.59 99.20
32 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 99.18
33 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6 99.16
34 INT127203 Positive_regulation of Mcf2l 14 0.43 9.84 7.03 99.08
35 INT169371 Positive_regulation of Positive_regulation of Mcf2l 1 0.43 0.78 0.28 99.08
36 INT8340 Negative_regulation of SHBG 49 0.57 35.96 4.73 98.88
37 INT4146 Binding of SHBG 49 0.47 31 4.71 98.88
38 INT49110 Regulation of Grip2 46 0.61 13.57 30.87 98.72
39 INT5455 Negative_regulation of Localization of CRH 16 0.49 7.31 6.41 98.68
40 INT520 Binding of Comt 24 0.48 8.98 12.21 98.68
41 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 98.56
42 INT276 Regulation of Ache 83 0.62 16.75 25.99 98.48
43 INT258059 Negative_regulation of Positive_regulation of GSR 3 0.41 1.79 0.33 98.40
44 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 98.32
45 INT3846 Positive_regulation of GSR 60 0.50 35.16 9.37 98.24
46 INT179760 Binding of IGKV2D-19 5 0.25 6.1 0.98 98.24
47 INT122882 Regulation of Ntrk2 13 0.62 9.7 4.3 98.20
48 INT1530 Regulation of Gh 382 0.61 115.96 112.47 98.16
49 INT217070 Gene_expression of Acsm3 8 0.25 6.27 1.75 98.16
50 INT232667 Binding of Pd 17 0.16 20.76 3.58 98.12
51 INT7585 Regulation of Crh 24 0.58 9.88 12.97 98.08
52 INT300166 Negative_regulation of FBXL15 1 0.03 4.07 0.41 98.08
53 INT90777 Gene_expression of Kcnn3 39 0.77 10.35 6.35 98.00
54 INT90778 Regulation of Gene_expression of Kcnn3 2 0.61 1.56 0.37 98.00
55 INT5454 Localization of CRH 124 0.79 79.18 41.53 97.84
56 INT65057 Regulation of Nfkb1 28 0.47 16.48 11.62 97.84
57 INT53468 Binding of Acsm3 26 0.24 20.87 2.95 97.80
58 INT47744 Binding of Slc6a4 21 0.48 5.52 9.45 97.80
59 INT264609 Regulation of Gene_expression of GSR 3 0.43 2.44 0.07 97.68
60 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 97.64
61 INT264213 Negative_regulation of TST 1 0.18 1.49 0.84 97.64
62 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82 97.56
63 INT4207 Regulation of Avp 267 0.62 63.72 115.33 97.52
64 INT73558 Regulation of IK 23 0.23 12.02 8.73 97.52
65 INT8065 Binding of AGT 54 0.48 20.54 10.85 97.32
66 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 97.20
67 INT7581 Binding of ADHD1 132 0.46 135.1 19.73 97.16
68 INT7340 Regulation of Grin1 87 0.62 30.37 57.93 96.96
69 INT16879 Binding of Crh 72 0.48 21.65 28.43 96.96
70 INT1590 Binding of PENK 27 0.47 2.99 12.81 96.96
71 INT210125 Regulation of Axin1 1 0.02 2.45 0.46 96.96
72 INT1361 Negative_regulation of Gnrhr 118 0.58 57.77 35.54 96.92
73 INT147793 Localization of COPD 70 0.64 89.01 7.3 96.84
74 INT40832 Localization of ADRB2 5 0.73 2.21 1.81 96.64
75 INT41475 Positive_regulation of Localization of ADRB2 2 0.49 0.18 1.12 96.64
76 INT66005 Regulation of Cnr1 47 0.61 19.21 34.52 96.60
77 INT8346 Gene_expression of Qrfp 136 0.70 19.49 70.21 96.60
78 INT8377 Positive_regulation of Gene_expression of RGD1564920 1 0.07 0.17 0.36 96.60
79 INT8378 Gene_expression of RGD1564920 1 0.09 0.17 0.35 96.60
80 INT1429 Gene_expression of PDYN 308 0.78 61.33 175.65 96.56
81 INT20964 Gene_expression of OPRK1 96 0.78 23.54 58.18 96.56
82 INT519 Negative_regulation of Comt 52 0.59 17.65 20.39 96.32
83 INT97149 Binding of Dpyd 3 0.14 1.73 0.25 96.28
84 INT258773 Negative_regulation of Binding of Dpyd 1 0.11 0.6 0 96.28
85 INT82055 Positive_regulation of Creb1 176 0.70 60.2 58.39 96.24
86 INT2780 Regulation of Gene_expression of Penk 265 0.62 32.45 143.88 96.24
87 INT57379 Positive_regulation of Phosphorylation of Creb1 79 0.69 28.24 30.25 96.24
88 INT178458 Negative_regulation of LIFR 13 0.47 8.75 2.48 96.16
89 INT178455 Localization of LIFR 6 0.61 2.24 0.83 96.16
90 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 96.14
91 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35 96.08
92 INT47690 Regulation of Bdnf 118 0.62 53.02 64.5 95.96
93 INT158 Localization of Prl 2431 0.81 378.96 952.2 95.92
94 INT1793 Localization of CGA 379 0.81 67.38 114.69 95.92
95 INT22909 Positive_regulation of Chdh 26 0.68 28.69 16.13 95.92
96 INT101121 Regulation of Comt 19 0.53 10.66 7.22 95.88
97 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 95.84
98 INT57380 Phosphorylation of Creb1 213 0.82 66.8 71.26 95.76
99 INT59365 Gene_expression of HTR1A 41 0.75 16.31 16.57 95.64
100 INT11669 Gene_expression of Htr2a 17 0.75 6.78 10.75 95.64
101 INT161539 Gene_expression of Htr6 1 0.19 0.43 0.34 95.64
102 INT159128 Localization of Nps 12 0.69 5.18 1.74 95.60
103 INT438 Gene_expression of Crh 376 0.78 159.11 169.17 95.52
104 INT149818 Gene_expression of Clock 81 0.70 14.15 10.04 95.52
105 INT152166 Regulation of GALR3 1 0.27 0.94 0.23 95.44
106 INT3597 Positive_regulation of Pla2g1b 37 0.63 17.94 11.41 95.24
107 INT152167 Regulation of GALR2 2 0.44 2.23 1.33 95.04
108 INT6228 Localization of Htr1a 14 0.78 0.46 6.2 95.04
109 INT317683 Gene_expression of Gabra3 1 0.76 5.54 3.05 95.00
110 INT317699 Negative_regulation of Gene_expression of Gabra3 1 0.58 1.41 0.72 95.00
111 INT35744 Binding of MAOB 13 0.46 7.52 4.26 94.88
112 INT35097 Gene_expression of Cux1 6 0.58 3.86 12.83 94.84
113 INT223921 Positive_regulation of Gene_expression of Cux1 1 0.49 0.83 2.36 94.84
114 INT95 Positive_regulation of Adrb1 34 0.62 11.95 14.41 94.80
115 INT20922 Positive_regulation of Localization of CRH 18 0.67 11.12 6.79 94.80
116 INT80419 Gene_expression of Kdm5d 50 0.62 22.49 6.1 94.80
117 INT255416 Regulation of Bp2 1 0.15 3.75 0.07 94.76
118 INT77502 Regulation of GALR1 2 0.27 1.03 0.6 94.76
119 INT79658 Transcription of GSR 8 0.68 3.59 2.19 94.68
120 INT179250 Negative_regulation of Transcription of GSR 2 0.56 1.7 0.18 94.68
121 INT170772 Negative_regulation of Gene_expression of GSR 8 0.41 3.05 0.7 94.68
122 INT3845 Gene_expression of GSR 79 0.76 44.69 11.19 94.68
123 INT46693 Regulation of Positive_regulation of Cfp 2 0.14 1.42 1.82 94.68
124 INT69952 Positive_regulation of IK 45 0.32 16.08 14.59 94.60
125 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41 94.60
126 INT145929 Regulation of Bax 20 0.60 18.12 5.35 94.60
127 INT99508 Regulation of Bcl2l1 12 0.61 10.44 2.71 94.60
128 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33 94.36
129 INT19 Regulation of Gnrhr 131 0.62 36.4 55.66 94.20
130 INT939 Gene_expression of PAEP 86 0.77 31.02 8.59 94.20
131 INT26369 Gene_expression of S100A6 19 0.65 5.39 1.81 94.16
132 INT24989 Positive_regulation of Cfp 125 0.61 29.55 64.9 94.16
133 INT351000 Binding of Adh7 1 0.01 3.4 0.03 94.16
134 INT107129 Positive_regulation of RLS 46 0.60 40.1 8.09 94.08
135 INT135372 Positive_regulation of Gsk3b 72 0.70 50.03 9.28 94.04
136 INT248419 Negative_regulation of Tph2 11 0.59 6.32 2.59 94.04
137 INT149014 Negative_regulation of Tph1 5 0.58 1.43 0.74 94.04
138 INT224872 Transcription of KLF10 1 0.52 0.67 1.78 94.00
139 INT224887 Positive_regulation of Transcription of Narp 1 0.21 0.35 0.79 94.00
140 INT224878 Transcription of Narp 1 0.24 0.34 0.77 94.00
141 INT58477 Gene_expression of Chdh 33 0.74 39.48 19.78 93.96
142 INT112730 Positive_regulation of ZNRF1 3 0.06 2.97 0.24 93.92
143 INT13995 Gene_expression of gr 96 0.74 48.21 26.54 93.84
144 INT36428 Binding of Chdh 42 0.47 48.04 26.54 93.80
145 INT6717 Negative_regulation of YY1 45 0.57 15.35 27.8 93.72
146 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68 93.70
147 INT661 Gene_expression of REN 100 0.78 48.21 11.36 93.68
148 INT128108 Gene_expression of Cplx1 1 0.75 0.76 3.31 93.60
149 INT128106 Regulation of Gene_expression of Cplx1 1 0.44 0.29 0.97 93.60
150 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 93.56
151 INT110862 Positive_regulation of Narp 10 0.40 2.8 7.13 93.56
152 INT5503 Negative_regulation of Gene_expression of Crh 38 0.59 16.82 21.34 93.40
153 INT9516 Negative_regulation of Gabrg1 149 0.53 27.83 91.02 93.36
154 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01 93.24
155 INT16261 Transcription of Bdnf 101 0.72 49.41 40.64 93.24
156 INT34370 Positive_regulation of Cfp 26 0.46 15.21 6.12 93.20
157 INT47680 Regulation of Gene_expression of Bdnf 92 0.62 41.61 53.24 93.20
158 INT224864 Positive_regulation of KLF10 1 0.67 2.48 7.37 93.20
159 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 93.16
160 INT17825 Gene_expression of Flvcr2 44 0.68 12.58 28.08 93.16
161 INT9489 Gene_expression of SFTPA1 112 0.66 55.38 66.45 93.08
162 INT5118 Regulation of SST 97 0.62 34.35 51.74 93.00
163 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21 93.00
164 INT208538 Regulation of Phosphorylation of Gsk3b 3 0.49 4.49 0.38 93.00
165 INT51244 Gene_expression of Umod 7 0.60 2.03 0.95 92.80
166 INT120740 Gene_expression of Dpys 1 0.34 0.34 0 92.80
167 INT7584 Gene_expression of Crh 112 0.78 39.15 25.33 92.72
168 INT11303 Gene_expression of Avp 116 0.78 39.23 23.88 92.72
169 INT58166 Regulation of Gene_expression of Avp 13 0.57 2.63 2.76 92.72
170 INT97649 Gene_expression of Dlat 48 0.66 13.77 8.94 92.68
171 INT263349 Negative_regulation of Gene_expression of Dlat 4 0.27 2.59 0.96 92.68
172 INT91070 Regulation of GSR 27 0.59 16.64 3.42 92.64
173 INT8122 Regulation of Htr1a 39 0.60 8.96 24.89 92.56
174 INT81002 Positive_regulation of Regulation of Htr1a 2 0.49 0.33 1.16 92.56
175 INT114286 Regulation of Regulation of Htr1a 1 0.44 0.33 0.49 92.56
176 INT100655 Regulation of BDNF 51 0.60 21.49 13.14 92.48
177 INT61999 Gene_expression of MAPT 19 0.75 15.4 1.3 92.48
178 INT23402 Binding of HLA-DOA 74 0.48 52.01 10.89 92.48
179 INT124370 Positive_regulation of Gene_expression of Gsk3b 47 0.67 24.56 5.4 92.48
180 INT255827 Positive_regulation of Gene_expression of MAPT 3 0.49 2.63 0.1 92.48
181 INT170769 Negative_regulation of Negative_regulation of GSR 2 0.41 0.95 0.06 92.40
182 INT186268 Positive_regulation of Tdo2 13 0.50 8 1.32 92.16
183 INT52924 Negative_regulation of GSR 49 0.58 28.08 9.28 92.08
184 INT170768 Regulation of Gene_expression of NR3C1 3 0.42 2.61 0.58 92.02
185 INT179857 Gene_expression of ATF7IP 14 0.65 4.12 0.89 92.00
186 INT317698 Gene_expression of Gabre 1 0.61 1.82 0.95 91.92
187 INT69438 Negative_regulation of Positive_regulation of ROS1 20 0.48 10.6 3.33 91.72
188 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 91.72
189 INT12484 Binding of Drd2 45 0.48 15.17 24.72 91.60
190 INT62576 Transcription of Creb1 34 0.69 16.97 10.6 91.52
191 INT1512 Binding of Prl 73 0.48 26.22 20.63 91.44
192 INT66040 Positive_regulation of Bdnf 114 0.69 67.67 51.81 91.40
193 INT66039 Positive_regulation of Ntrk2 53 0.69 15.87 17.23 91.40
194 INT66318 Gene_expression of NR3C1 26 0.76 20 7.55 91.40
195 INT74509 Positive_regulation of Datd 2 0.18 0.85 1.81 91.40
196 INT50334 Negative_regulation of Cnr1 84 0.58 30.86 51.75 91.12
197 INT248424 Negative_regulation of POU6F1 1 0.57 0.81 0.1 91.12
198 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 91.08
199 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71 91.08
200 INT154668 Gene_expression of Atn1 3 0.45 2.74 0.73 91.08
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