D:Aggression

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Disease Term
Synonyms Aggressions, AGGRESSIVE BEHAVIOR, Aggressive Behaviour, Aggressiveness, Violence
Documents 2568
Hot Single Events 200
Hot Interactions 39

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Aggression. They are ordered first by their relevance to Aggression and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT255463 Binding of Avp and Avpr1a 1 0.06 0.67 0.54 100.00
2 INT266103 Binding of COMT and SNRNP70 1 0.04 0.78 0.21 100.00
3 INT340179 Binding of Oxt and Oxtr 10 0.31 2.53 0.19 99.30
4 INT354064 Binding of Oxtr and Avpr1a 1 0.26 1.37 0.03 99.30
5 INT354081 Binding of Oxtr and Avpr1b 1 0.26 1.37 0.03 99.30
6 INT340177 Binding of Oxt and Avpr1a 6 0.15 2.24 0.29 99.30
7 INT354063 Binding of Oxt and Avpr1b 1 0.15 1.37 0.03 99.30
8 INT354068 Binding of Avpr1b and Avpr1a 1 0.29 1.36 0.03 99.30
9 INT127887 SLC6A3 Regulation of Drd2 1 0.34 0.68 0.34 99.08
10 INT122480 Binding of SERPINE1 and PLAU 4 0.40 2.75 0.06 98.48
11 INT345196 Lpar2 Positive_regulation of Gene_expression of VEGFA 1 0.08 2.14 0.2 98.08
12 INT345186 Lpar2 Positive_regulation of Gene_expression of Plau 1 0.05 2.2 0.2 98.08
13 INT265610 Positive_regulation of TAF8 Positive_regulation of Msc 1 0.03 0.89 0 98.08
14 INT156661 Binding of Pgls and Sdhb 1 0.01 1.43 0.25 97.80
15 INT71904 Binding of ESR1 and PGR 6 0.34 3.79 0.27 96.84
16 INT252851 Binding of GFAP and Ema 1 0.05 1.98 0 95.52
17 INT265609 Msc Positive_regulation of TAF8 1 0.03 0.7 0.08 92.56
18 INT205031 Crh Positive_regulation of Crhr2 1 0.45 1.11 0.11 92.40
19 INT205030 Crh Positive_regulation of Crhr1 2 0.54 1.33 0.51 92.40
20 INT205032 Crh Regulation of Crhr1 1 0.21 0.84 0.03 92.40
21 INT176130 AKT1 Regulation of Gene_expression of COX18 1 0.13 0.82 0.11 89.60
22 INT345194 Lpar1 Positive_regulation of Gene_expression of VEGFA 1 0.07 0.87 0.1 89.52
23 INT345193 VEGFA Regulation of Gene_expression of Dmbx1 1 0.01 0.82 0.09 88.12
24 INT345195 VEGFA Positive_regulation of Gene_expression of Dmbx1 1 0.01 0.82 0.09 88.12
25 INT153620 Binding of Ntrk1 and WNK1 1 0.02 0.85 0.12 87.68
26 INT342251 Binding of Trp53 and Tymp 1 0.21 1.01 0 86.96
27 INT196523 Binding of MMP2 and TIMP1 3 0.43 1.94 0.85 86.48
28 INT347638 Negative_regulation of Binding of Atp9a and Hdac4 1 0.01 0.97 0.14 85.68
29 INT347639 Binding of Atp9a and Hdac4 1 0.01 0.97 0.14 85.24
30 INT196526 Binding of TIMP1 and TIMP2 1 0.45 1.49 0.71 84.96
31 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33 84.16
32 INT327979 Positive_regulation of CASP9 Positive_regulation of Gene_expression of CASP3 1 0.07 0.78 0 84.16
33 INT280824 Binding of Avp and Crh 1 0.05 0.55 0 84.08
34 INT265603 Msc Positive_regulation of Gene_expression of Il6 1 0.16 1.79 0.2 82.56
35 INT163863 Binding of MIB1 and Vim 1 0.02 1.06 0.21 80.48
36 INT163864 Binding of MIB1 and Ema 1 0.04 1.07 0.21 80.48
37 INT176135 AKT1 Regulation of Localization of CYCS 1 0.43 2.16 0.35 80.36
38 INT176134 AKT1 Regulation of Gene_expression of BIRC3 1 0.08 1.09 0.17 80.36
39 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17 80.36
40 INT315907 Binding of ALB and Sparc 1 0.06 3.67 0 79.20
41 INT83370 Binding of HRAS and TP53 1 0.30 0.59 0.11 78.56
42 INT328775 Binding of Cd44 and Epcam 1 0.08 1.34 0 77.76
43 INT24395 Binding of CALCA and CLPP 1 0.03 0.17 0.96 76.84
44 INT327980 PNLIP Regulation of TNFRSF11A 1 0.15 0.89 0 75.48
45 INT327973 PNLIP Negative_regulation of NFKBIB 1 0.07 0.9 0 75.48
46 INT172205 Binding of Maoa and ADHD1 1 0.03 0.82 0.05 75.20
47 INT276389 Binding of Trp53 and KRT20 1 0.01 0.97 0.03 74.64
48 INT138384 Binding of Htr1b and ADHD1 2 0.07 1.46 0.42 74.60
49 INT185358 Binding of MCS and PCS 7 0.22 3.34 0.57 74.24
50 INT24393 Regulation of NPVF Regulation of CLPP 1 0.00 0.13 0.69 73.92
51 INT127672 Binding of NGFR and NTRK1 1 0.17 2.28 0.97 73.52
52 INT185281 Binding of CDK6 and CDKN2A 1 0.29 0.87 0 73.40
53 INT24394 NPVF Regulation of CLPP 1 0.00 0.13 0.68 73.00
54 INT245110 Binding of MMP9 and Mmp9 1 0.08 1.53 0 72.88
55 INT276300 TAT Regulation of Gene_expression of VEGFA 1 0.14 1.58 0 72.48
56 INT24396 CALCB Regulation of CLPP 1 0.00 0.13 0.65 72.36
57 INT185279 Binding of CCND1 and CDK4 4 0.13 2.05 0.08 72.36
58 INT185277 CDK6 Negative_regulation of Binding of CDK4 and CDK6 1 0.20 0.87 0 72.36
59 INT185280 Binding of CDK4 and CDK6 1 0.20 0.87 0 72.36
60 INT185276 CDK4 Negative_regulation of Binding of CDK4 and CDK6 1 0.20 0.87 0 72.36
61 INT343163 ACSL4 Regulation of Gene_expression of PTGS2 1 0.08 0.5 0 72.24
62 INT185278 Binding of CCND1 and CDK6 3 0.13 1.62 0.08 72.00
63 INT249962 Binding of KIT and KITLG 6 0.19 3.69 0.17 68.64
64 INT252902 PTTG1 Regulation of MMP2 1 0.01 1.5 0.14 65.32
65 INT298755 Gopc Regulation of Gene_expression of NOVA2 1 0.02 0.55 0.03 64.52
66 INT269214 SNAI1 Positive_regulation of Positive_regulation of CDH1 1 0.35 0.71 0.04 63.76
67 INT269211 SNAI1 Positive_regulation of Gene_expression of CDH1 1 0.40 0.73 0.04 63.76
68 INT345171 Binding of Trip6 and Magi3 1 0.03 1.65 0.14 63.08
69 INT345146 Binding of Trip6 and Siva1 1 0.02 1.6 0.14 63.08
70 INT196525 Binding of MMP2 and MMP9 2 0.32 2.49 0.78 62.96
71 INT257397 Binding of FGD1 and INS 1 0.07 0.27 0.21 62.76
72 INT257398 Binding of FGD1 and GHRH 1 0.03 0.27 0.2 62.76
73 INT290475 POU3F2 Negative_regulation of Mitf 1 0.43 1.14 0 62.40
74 INT327969 Binding of PNLIP and TNFRSF11A 1 0.09 0.89 0 61.32
75 INT252901 PTTG1 Regulation of Gene_expression of TSC1 1 0.00 1.61 0.13 60.24
76 INT327703 Cish Regulation of Transcription of Comt 1 0.13 0.77 0.12 59.56
77 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85 59.52
78 INT312372 Binding of MME and TCHP 1 0.06 1.56 0 56.00
79 INT101926 Binding of Dio1 and Drd2 4 0.28 0.39 1.66 55.92
80 INT235884 Htr3a Regulation of Nr3c1 1 0.00 0.63 0.32 54.36
81 INT288545 Gsk3b Negative_regulation of gr 1 0.25 0.38 0.38 52.24
82 INT343159 ACSL4 Regulation of Gene_expression of LOX 1 0.07 1.04 0 51.92
83 INT345173 Binding of Siva1 and Lpar2 1 0.05 0.75 0.06 51.84
84 INT343162 ACSL4 Regulation of LOX 1 0.03 1.04 0 51.52
85 INT343155 ACSL4 Regulation of CPOX 1 0.01 1.03 0 51.20
86 INT276386 Gtf3a Regulation of PTPN6 1 0.00 0.86 0.04 50.88
87 INT276392 Timp1 Regulation of PTPN6 1 0.02 0.87 0.04 50.88
88 INT345165 Lpar5 Negative_regulation of Dmbx1 1 0.05 1.24 0.13 50.80
89 INT345191 Lpar4 Negative_regulation of Dmbx1 1 0.04 1.25 0.13 50.80
90 INT276376 Gtf3a Regulation of CD44 1 0.00 0.86 0.04 50.16
91 INT276385 Timp1 Regulation of CD44 1 0.04 0.87 0.04 50.16
92 INT181616 INS Positive_regulation of IRS1 1 0.01 1 0.79 48.56
93 INT332795 Negative_regulation of Vhl Positive_regulation of Positive_regulation of Cxcr4 1 0.02 1.64 0.05 48.24
94 INT327982 PNLIP Regulation of Gene_expression of CASP3 1 0.13 0.58 0 48.08
95 INT181615 SRC Positive_regulation of IRS1 1 0.01 0.98 0.77 46.84
96 INT327978 PNLIP Regulation of Regulation of CASP9 1 0.19 0.57 0 46.08
97 INT280806 Avpr1b Positive_regulation of Localization of Pomc 1 0.19 0.17 0 45.48
98 INT260518 Binding of Prnp and Gopc 2 0.13 1.06 0 45.36
99 INT319483 Binding of LCT and HSR 1 0.11 0.23 0 44.96
100 INT205033 Ucn Positive_regulation of Crhr2 1 0.22 0.15 0.08 44.36
101 INT225266 Erbb2 Positive_regulation of Gene_expression of VEGFA 1 0.04 0.79 0 43.96
102 INT121050 Crh Regulation of Localization of Pomc 4 0.43 0.6 0.22 41.00
103 INT280840 Avp Regulation of Localization of Pomc 1 0.02 0.16 0 40.80
104 INT127677 NGF Regulation of Gene_expression of NGFR 1 0.20 1.11 0.5 40.56
105 INT205160 Binding of CD44 and MMP2 1 0.09 0.61 0.07 40.48
106 INT127673 NGF Regulation of Gene_expression of NTRK1 1 0.48 2.12 0.92 39.60
107 INT301410 Binding of Lpar1 and Lpar2 2 0.20 0.65 0 38.20
108 INT345152 Binding of Lpar1 and Siva1 1 0.03 0.66 0 38.20
109 INT343161 ACSL4 Regulation of Gene_expression of TSPO 1 0.25 0.75 0 36.80
110 INT304468 Binding of AGRP and KRT122P 1 0.24 0.65 0.15 35.32
111 INT249567 Positive_regulation of Binding of Oprd1 and Psmd1 1 0.01 0.66 2.5 34.64
112 INT186148 Camk4 Positive_regulation of Phosphorylation of Creb1 2 0.50 1.11 0.4 34.64
113 INT249566 Binding of Oprd1 and Psmd1 1 0.01 0.82 3.8 34.12
114 INT270680 Fos Regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 0.03 0.39 1.05 33.92
115 INT345151 Binding of Trip6 and Lpar2 1 0.20 1.33 0 33.80
116 INT205155 Negative_regulation of Binding of CD44 and MMP9 1 0.32 1.98 0.23 33.76
117 INT304027 Negative_regulation of PTEN Positive_regulation of Positive_regulation of AKT1 1 0.32 1.86 0 31.20
118 INT236003 Binding of HTR1A and Grin1 1 0.01 0.7 0.63 31.00
119 INT225262 Egf Regulation of Gene_expression of S100a7a 1 0.04 3.31 0.06 30.88
120 INT224687 Il1 Positive_regulation of Bmp2 1 0.00 0.3 0.31 29.52
121 INT245103 TNFRSF11B Negative_regulation of MMP14 1 0.02 1.15 0 27.92
122 INT92423 EC3 Negative_regulation of Mme 1 0.02 0.28 0.86 25.00
123 INT92422 Mme Negative_regulation of EC3 1 0.01 0.14 0.43 25.00
124 INT127676 NGF Regulation of TNFRSF1B 1 0.21 1.02 0.42 25.00
125 INT127675 NGF Regulation of NTRK1 1 0.48 1.01 0.42 25.00
126 INT127674 NGF Regulation of Gene_expression of TNFRSF1B 1 0.48 1.02 0.42 25.00
127 INT276381 Timp1 Positive_regulation of CD44 1 0.07 0.72 0.04 24.64
128 INT327971 PNLIP Positive_regulation of Gene_expression of BAX 1 0.43 1.95 0 24.40
129 INT234612 Binding of KIT and STIP1 1 0.04 1 0 24.08
130 INT257223 Ltp Positive_regulation of Gene_expression of Nos1 1 0.03 0.07 0.24 21.28
131 INT290480 MLANA Regulation of Gene_expression of Mitf 1 0.27 0.64 0 21.28
132 INT313596 ESR1 Positive_regulation of Gene_expression of PGR 1 0.05 1 0 21.12
133 INT290483 RAB27A Regulation of Gene_expression of Mitf 1 0.25 0.64 0 21.00
134 INT290482 GPR143 Regulation of Gene_expression of Mitf 1 0.36 0.64 0 20.52
135 INT327976 PNLIP Negative_regulation of Gene_expression of BCL2 1 0.29 0.53 0 19.84
136 INT354062 Avp Regulation of Lyz2 1 0.00 0.12 0.38 19.68
137 INT345183 Binding of Lhx3 and Trip6 1 0.03 0.66 0.03 19.24
138 INT345188 Binding of Lhx3 and Lpar2 1 0.06 0.66 0.03 18.80
139 INT343156 Binding of TSPO and DBI 1 0.04 0.63 0 16.56
140 INT307585 Binding of EGFR and MET 1 0.11 0.52 0 14.64
141 INT307584 Binding of EGFR and IGF1R 1 0.03 0.52 0 13.84
142 INT327970 GOPC Regulation of Gene_expression of BAD 1 0.08 0.6 0 13.76
143 INT327975 GOPC Regulation of Gene_expression of BAX 1 0.15 0.6 0 13.76
144 INT327974 GOPC Regulation of Gene_expression of BCL2 1 0.13 0.6 0 13.76
145 INT211875 Binding of CDS1 and SMUG1 1 0.03 1.04 0.07 13.52
146 INT290478 Mitf Positive_regulation of HIF1A 1 0.57 0.61 0 13.48
147 INT290479 Binding of HIF1A and Mitf 1 0.30 1.29 0 13.48
148 INT276337 Timp1 Positive_regulation of Il10 1 0.01 0.76 0.05 13.28
149 INT307586 Binding of EGFR and CDCP1 1 0.01 0.51 0 12.64
150 INT227953 Chrm2 Regulation of Chrm5 1 0.21 0.33 0.13 12.28
151 INT227956 Drd2 Regulation of Chrm2 1 0.07 0.38 0.13 12.28
152 INT227957 Chrm4 Regulation of Localization of Drd2 1 0.19 0.38 0.13 12.28
153 INT227960 Drd2 Regulation of Chrm5 1 0.26 0.38 0.13 12.28
154 INT227958 Chrm2 Regulation of Localization of Drd2 1 0.17 0.38 0.13 12.28
155 INT227959 Drd2 Regulation of Chrm4 1 0.08 0.38 0.13 12.28
156 INT227954 Chrm4 Regulation of Chrm5 1 0.24 0.33 0.13 12.28
157 INT307225 CYLD Regulation of TNFRSF11A 1 0.14 0.81 0 12.00
158 INT328780 Binding of TBK1 and Memo1 1 0.09 0.6 0 10.72
159 INT202183 PLAU Regulation of Protein_catabolism of PLAUR 1 0.11 1.25 0.21 7.36
160 INT202184 SERPINE1 Regulation of Protein_catabolism of PLAUR 1 0.23 1.25 0.21 7.36
161 INT204492 Negative_regulation of Binding of App and Fmr1 1 0.42 0.28 0 6.32
162 INT66535 Binding of Pnoc and Oprl1 43 0.54 5.93 32.4 5.00
163 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 5.00
164 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
165 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 5.00
166 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25 5.00
167 INT182194 Binding of IL8 and CXCR2 10 0.56 7.14 4.16 5.00
168 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11 5.00
169 INT208572 Binding of IL8 and CXCR1 6 0.33 5.2 3.08 5.00
170 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 5.00
171 INT197379 Tbs1 Positive_regulation of Ltp 6 0.07 1.87 2.21 5.00
172 INT239037 Binding of Cd28 and Cd86 9 0.16 3.69 2.14 5.00
173 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99 5.00
174 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
175 INT172206 Binding of Slc6a3 and ADHD1 2 0.03 2.76 1.61 5.00
176 INT208991 Binding of CALM1 and Ca2 10 0.06 1.34 1.55 5.00
177 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54 5.00
178 INT190772 Il4 Negative_regulation of Gene_expression of Ptger2 1 0.03 1.28 1.49 5.00
179 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48 5.00
180 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45 5.00
181 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45 5.00
182 INT172203 Binding of Comt and Maoa 1 0.31 0.98 1.43 5.00
183 INT190775 Gene_expression of Il4 Negative_regulation of Positive_regulation of FOSL1 1 0.39 2.42 1.4 5.00
184 INT249565 Binding of Gabrg1 and Oprd1 1 0.00 0.1 1.33 5.00
185 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27 5.00
186 INT280480 Binding of Bdnf and Ngfr 5 0.25 3.14 1.27 5.00
187 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18 5.00
188 INT262336 Binding of Abat and Tmem132a 1 0.00 1.39 1.14 5.00
189 INT190771 Gene_expression of Il4 Negative_regulation of Gene_expression of Mapk14 1 0.15 1.14 1.13 5.00
190 INT190770 Il4 Negative_regulation of Gene_expression of Mapk14 1 0.20 1.14 1.13 5.00
191 INT196812 Ppp1r1b Negative_regulation of Ppp1cc 3 0.07 0.13 1.12 5.00
192 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11 5.00
193 INT242624 Binding of Ngf and Ntrk2 5 0.24 0.48 1.11 5.00
194 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
195 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1 5.00
196 INT30905 SST Negative_regulation of Localization of GCG 2 0.12 1.56 1.04 5.00
197 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 5.00
198 INT167173 Binding of Ccl2 and Ccr2 2 0.30 1.15 0.98 5.00
199 INT75283 SST Negative_regulation of Localization of INS 2 0.47 1.45 0.96 5.00
200 INT81127 Binding of Gabrd and Abat 3 0.25 0 0.96 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Aggression. They are ordered first by their pain relevance and then by number of times they were reported in Aggression. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT122924 Binding of ipv 27 0.42 31.81 1.99 100.00
2 INT195817 Gene_expression of ipv 28 0.58 31.04 1.86 100.00
3 INT160280 Positive_regulation of ipv 14 0.44 15.73 1.02 100.00
4 INT188887 Binding of NBPF1 1 0.01 12.41 0.48 100.00
5 INT149229 Localization of ipv 8 0.65 10.34 1.06 100.00
6 INT291828 Positive_regulation of Gene_expression of ipv 3 0.44 7.4 0.89 100.00
7 INT126503 Negative_regulation of ipv 5 0.46 4.32 0.53 100.00
8 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35 100.00
9 INT451 Regulation of Oxt 142 0.62 22.07 69.42 100.00
10 INT332472 Regulation of Localization of ipv 1 0.37 3.15 0.41 100.00
11 INT47553 Gene_expression of ARSH 11 0.42 4.93 0.65 100.00
12 INT105948 Gene_expression of AURKA 5 0.65 4.26 0.03 100.00
13 INT42308 Regulation of ipv 4 0.38 2.72 1.17 100.00
14 INT332473 Negative_regulation of Gene_expression of ipv 1 0.35 2.7 0.35 100.00
15 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 100.00
16 INT188885 Positive_regulation of NBPF1 1 0.01 0.87 0 100.00
17 INT197073 Gene_expression of LAGE3 1 0.02 0.75 0 100.00
18 INT204018 Localization of Gsk3b 27 0.71 13.67 1.87 100.00
19 INT135374 Binding of Gsk3b 46 0.48 24.36 4.75 100.00
20 INT259116 Transcription of BRCA1 3 0.44 3.77 0 100.00
21 INT223400 Transcription of ipv 1 0.59 0.58 0 100.00
22 INT291827 Positive_regulation of Localization of ipv 1 0.44 0.71 0.07 100.00
23 INT30927 Regulation of Mif-ps1 7 0.54 0.96 3.2 100.00
24 INT16390 Regulation of Plg 13 0.48 6.72 3.2 100.00
25 INT188886 Negative_regulation of NBPF1 1 0.01 1.12 0 100.00
26 INT288540 Negative_regulation of Binding of Gsk3b 4 0.53 2.12 0.43 100.00
27 INT48312 Gene_expression of NTRK1 72 0.78 38.21 22.24 100.00
28 INT30925 Gene_expression of Mif-ps1 6 0.73 1.63 4.74 100.00
29 INT30928 Regulation of Gene_expression of Mif-ps1 1 0.35 0.33 0.35 100.00
30 INT16389 Gene_expression of Plg 80 0.67 36.88 6.74 100.00
31 INT30926 Regulation of Gene_expression of Plg 11 0.45 2.14 0.78 100.00
32 INT204002 Negative_regulation of Gene_expression of Gsk3b 15 0.55 8.57 0.77 100.00
33 INT39818 Positive_regulation of Cfd 8 0.45 3.36 1.15 100.00
34 INT140193 Gene_expression of Mmp3 58 0.71 49.65 25.4 100.00
35 INT177581 Regulation of Fig4 113 0.41 39.26 27.75 100.00
36 INT100381 Positive_regulation of Positive_regulation of HIF1A 12 0.49 12.05 2.17 100.00
37 INT8713 Regulation of Tac1 56 0.60 25.29 45.94 100.00
38 INT3028 Negative_regulation of Oxt 76 0.58 18.52 24.4 100.00
39 INT265607 Gene_expression of TAF8 11 0.32 9.91 0.35 100.00
40 INT72822 Negative_regulation of Gene_expression of Oxt 6 0.41 2.48 1.12 100.00
41 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78 100.00
42 INT79140 Binding of HCC 36 0.31 46.96 1.87 100.00
43 INT102989 Regulation of Gene_expression of MMP3 10 0.53 3.29 1.47 100.00
44 INT69649 Regulation of CA5P 3 0.20 2.56 0.81 100.00
45 INT88579 Gene_expression of Hal 2 0.21 0.52 0.28 100.00
46 INT205384 Negative_regulation of Gene_expression of Mpst 1 0.25 0.46 0.08 100.00
47 INT221276 Gene_expression of Napb 1 0.06 1.1 0.06 100.00
48 INT354034 Regulation of Negative_regulation of Avpr1a 1 0.33 2.94 0.09 99.98
49 INT12388 Negative_regulation of Crhr1 17 0.59 9.47 3.33 99.96
50 INT155309 Negative_regulation of Oas1g 2 0.07 0.75 0.38 99.96
51 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 99.96
52 INT4450 Negative_regulation of KNCN 2 0.07 0.46 0.35 99.96
53 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.92
54 INT2910 Regulation of Abat 169 0.62 36.95 153.53 99.92
55 INT114826 Gene_expression of Tymp 40 0.58 22.97 3.71 99.92
56 INT1758 Positive_regulation of Gene_expression of TIMP1 62 0.69 31.72 13.98 99.92
57 INT2148 Negative_regulation of Oxt 105 0.59 11.42 57 99.90
58 INT81496 Gene_expression of CNR2 68 0.75 30.04 24.92 99.90
59 INT21344 Negative_regulation of Penk 34 0.57 8.83 23.32 99.82
60 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 99.80
61 INT255461 Positive_regulation of Avpr1a 3 0.45 1.3 0.91 99.78
62 INT1807 Negative_regulation of Bcar1 9 0.38 4.04 4.59 99.76
63 INT124370 Positive_regulation of Gene_expression of Gsk3b 47 0.67 24.56 5.4 99.72
64 INT38173 Gene_expression of Ang 40 0.75 32.63 8.86 99.70
65 INT343192 Gene_expression of ACSL4 1 0.75 20.21 0.35 99.68
66 INT343189 Regulation of Gene_expression of ACSL4 1 0.59 1.49 0 99.68
67 INT205385 Gene_expression of Mpst 1 0.40 0.46 0.08 99.64
68 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 99.60
69 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23 99.60
70 INT14043 Binding of HP 52 0.30 26.56 7.76 99.60
71 INT205024 Gene_expression of Hsd3b5 1 0.65 0.64 0 99.60
72 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78 99.60
73 INT11279 Positive_regulation of Penk 65 0.70 18.72 30.29 99.60
74 INT168913 Negative_regulation of Avpr1a 7 0.43 5.88 2.47 99.58
75 INT663 Negative_regulation of Adrb3 55 0.59 15.95 14.68 99.56
76 INT26680 Negative_regulation of Mif-ps1 6 0.50 0.71 3.14 99.56
77 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 99.54
78 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4 99.54
79 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72 99.52
80 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 99.52
81 INT129961 Regulation of Gene_expression of MMP1 15 0.46 4.88 2.51 99.52
82 INT77246 Positive_regulation of WNK1 5 0.10 4.24 1.13 99.52
83 INT34184 Localization of FGD1 7 0.65 2.68 4.21 99.50
84 INT24735 Regulation of TF 10 0.44 5.55 0.65 99.48
85 INT17324 Negative_regulation of Plg 26 0.38 13.5 4.05 99.44
86 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24 99.44
87 INT1491 Regulation of Rtcd1 33 0.53 5.17 13.4 99.42
88 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68 99.38
89 INT36173 Positive_regulation of Gs 17 0.43 7.48 8.19 99.36
90 INT36176 Negative_regulation of Gs 4 0.18 0.96 0.31 99.36
91 INT36175 Positive_regulation of Negative_regulation of Gs 2 0.20 0.23 0.1 99.36
92 INT36174 Negative_regulation of Positive_regulation of Gs 1 0.18 0.23 0.1 99.36
93 INT162 Regulation of Prl 794 0.62 165.01 322.24 99.34
94 INT37335 Gene_expression of Nsdhl 45 0.51 24.36 4.58 99.32
95 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 99.32
96 INT139237 Negative_regulation of Gene_expression of CDH1 23 0.57 24.31 1.28 99.32
97 INT352885 Positive_regulation of Dsg4 1 0.29 0.46 0.26 99.32
98 INT148898 Negative_regulation of Gene_expression of Nr4a2 3 0.54 1.13 0.26 99.26
99 INT148896 Negative_regulation of Gene_expression of Npas4 1 0.41 0.65 0.08 99.26
100 INT193405 Gene_expression of OFC1 14 0.53 3.33 1.42 99.24
101 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51 99.24
102 INT64112 Regulation of Gene_expression of Nos1 22 0.62 21.45 14.76 99.24
103 INT64111 Negative_regulation of Gene_expression of Nos1 22 0.57 8.96 6.02 99.24
104 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76 99.24
105 INT682 Negative_regulation of AVP 97 0.59 50.67 23.91 99.24
106 INT2415 Binding of MAOA 26 0.47 13.26 11.86 99.16
107 INT205028 Regulation of Gene_expression of Crhr1 1 0.45 0.97 0 99.16
108 INT181589 Binding of OPN1SW 13 0.32 9.47 4.07 99.16
109 INT1321 Localization of Oprl1 18 0.76 1.74 9.56 99.12
110 INT127981 Gene_expression of Trpc1 25 0.77 10.51 11.67 99.12
111 INT145127 Positive_regulation of Gene_expression of Trpc1 4 0.30 3.56 1.46 99.12
112 INT145128 Gene_expression of Trpc6 12 0.75 5.59 1.17 99.12
113 INT145129 Positive_regulation of Gene_expression of Trpc6 4 0.67 2.91 0.51 99.12
114 INT148897 Gene_expression of Npas4 1 0.74 1.06 0.16 99.10
115 INT102200 Gene_expression of Nr4a2 9 0.72 3.69 1.28 99.10
116 INT49172 Regulation of Nos1 43 0.52 27.53 23.66 99.10
117 INT894 Binding of Avp 84 0.48 29.16 29.63 99.08
118 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 99.06
119 INT29051 Regulation of OPRL1 6 0.60 1.29 5.81 99.04
120 INT107605 Gene_expression of MMP14 26 0.64 25.88 4.49 99.04
121 INT8075 Localization of Crh 64 0.81 25.41 19.45 99.00
122 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 99.00
123 INT7470 Positive_regulation of Gene_expression of Avp 37 0.70 19.55 19.96 99.00
124 INT185295 Gene_expression of RASL12 2 0.13 2.02 0 98.92
125 INT1281 Negative_regulation of Maoa 203 0.59 22.47 91.66 98.84
126 INT63361 Gene_expression of CD44 126 0.77 71.58 12.96 98.80
127 INT16580 Negative_regulation of Htr2a 18 0.57 3.8 9.63 98.76
128 INT300926 Gene_expression of OBFC1 15 0.65 6.97 1.22 98.74
129 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 98.72
130 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 98.72
131 INT44954 Gene_expression of APP 191 0.78 105.86 23.9 98.72
132 INT10870 Regulation of IgG 67 0.59 43.27 12.74 98.72
133 INT62710 Gene_expression of HGF 160 0.78 88.27 26.14 98.72
134 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 98.72
135 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63 98.72
136 INT24328 Gene_expression of Egf 97 0.75 59.65 9.42 98.72
137 INT92916 Gene_expression of Acta2 50 0.74 17.52 6.11 98.72
138 INT7584 Gene_expression of Crh 112 0.78 39.15 25.33 98.70
139 INT101955 Gene_expression of Crhr2 6 0.64 3.62 2.31 98.70
140 INT2490 Regulation of Sct 44 0.62 9.45 13.11 98.68
141 INT127679 Positive_regulation of Gene_expression of NGFR 7 0.67 4.98 1.43 98.68
142 INT154139 Gene_expression of Top2a 2 0.72 4.23 0.19 98.64
143 INT99608 Transcription of MMP9 18 0.65 9.67 4.11 98.64
144 INT55736 Transcription of MMP2 11 0.68 5.78 2.28 98.64
145 INT53131 Transcription of TIMP1 8 0.68 3.89 1.5 98.64
146 INT94429 Transcription of TIMP2 3 0.61 4.05 0.67 98.64
147 INT326180 Positive_regulation of Gene_expression of Top2a 1 0.38 1.38 0.13 98.64
148 INT320708 Binding of PMVK 1 0.36 0.58 0.03 98.64
149 INT5595 Positive_regulation of Pdyn 223 0.70 48.37 130.14 98.60
150 INT3531 Regulation of Adrb2 7 0.44 1.48 2.25 98.60
151 INT32545 Localization of Gsk3b 9 0.07 2.88 1.11 98.58
152 INT85655 Gene_expression of Crhr1 17 0.68 9.34 6.31 98.52
153 INT115 Negative_regulation of Maoa 65 0.59 16.27 38.66 98.52
154 INT1705 Gene_expression of pCA 126 0.65 88.65 34.81 98.52
155 INT10754 Positive_regulation of Gene_expression of PCa 18 0.41 21.81 4.17 98.52
156 INT1414 Regulation of Oprl1 169 0.62 32.05 139.99 98.48
157 INT92112 Negative_regulation of Tmem132a 3 0.38 1.6 4.92 98.48
158 INT22679 Binding of SERPINE1 25 0.36 17.33 2.36 98.48
159 INT937 Positive_regulation of Oxt 195 0.70 37.82 49.3 98.44
160 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 98.44
161 INT103739 Negative_regulation of Gene_expression of Crh 19 0.59 10.19 3.17 98.40
162 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 98.38
163 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54 98.36
164 INT104039 Positive_regulation of Crhr1 15 0.70 8.34 10.99 98.36
165 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66 98.36
166 INT112363 Regulation of Gene_expression of HIF1A 6 0.60 2.28 0.61 98.36
167 INT93777 Negative_regulation of Rgs2 3 0.43 2.5 2.81 98.34
168 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 98.32
169 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 98.32
170 INT96492 Gene_expression of NGFR 24 0.00 12.3 4.59 98.32
171 INT27798 Gene_expression of Ntrk2 111 0.78 56.08 42.68 98.32
172 INT90567 Negative_regulation of Gene_expression of Gad1 4 0.41 2.88 1.36 98.30
173 INT123645 Negative_regulation of Transcription of Gad1 2 0.42 0.76 0.52 98.30
174 INT123644 Negative_regulation of Gene_expression of Reln 2 0.41 0.95 0.07 98.30
175 INT209334 Regulation of Filipino 1 0.09 1.4 0.29 98.24
176 INT354046 Regulation of Avpr1b 1 0.58 3.96 0.63 98.22
177 INT8103 Binding of TP53 46 0.44 40.2 2.96 98.20
178 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 98.20
179 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 98.16
180 INT188884 Localization of DDX41 3 0.60 2.56 0.09 98.12
181 INT123643 Gene_expression of Reln 19 0.75 1.85 1.13 98.12
182 INT123646 Transcription of Reln 1 0.52 0.66 0.07 98.12
183 INT139366 Gene_expression of PROM1 98 0.77 67.84 3.39 98.08
184 INT122481 Binding of PLAU 10 0.36 6.1 1.16 98.08
185 INT181812 Positive_regulation of Msc 20 0.66 13.47 0.86 98.08
186 INT142435 Gene_expression of NES 86 0.78 47.53 4.92 98.08
187 INT265581 Positive_regulation of Positive_regulation of Msc 2 0.19 2.01 0 98.08
188 INT117344 Binding of AREG 4 0.11 2.14 0.34 98.06
189 INT230965 Positive_regulation of AREG 4 0.24 2.48 0.15 98.06
190 INT2397 Gene_expression of Maoa 12 0.77 11.85 3.88 98.04
191 INT9780 Regulation of Penk 30 0.60 6.78 17.19 98.04
192 INT81326 Positive_regulation of Gene_expression of Ang 17 0.67 18.5 5.46 98.00
193 INT276358 Gene_expression of MIR150 42 0.74 38.44 7.82 98.00
194 INT5598 Negative_regulation of Pdyn 95 0.59 14.4 55.43 97.96
195 INT118589 Regulation of OFC1 11 0.23 3.35 2.94 97.96
196 INT144430 Gene_expression of Erbb2 137 0.77 103.87 8.66 97.96
197 INT191145 Positive_regulation of Gene_expression of Atp8a1 14 0.67 5.24 1.02 97.92
198 INT22143 Gene_expression of Gad1 35 0.76 14.4 15.4 97.90
199 INT96641 Transcription of Gad1 3 0.60 0.84 1.36 97.90
200 INT49170 Negative_regulation of Nos1 116 0.59 60.66 58.87 97.84
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