D:Aging

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Disease Term
Synonyms Ageing, AGING BIOLOGICAL, Biological Aging, Increase In Lifespan, Increased Lifespan, LONGEVITY, SENESCENCE
Documents 5280
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Aging. They are ordered first by their relevance to Aging and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT305271 Binding of Lep and Obsty1 1 0.06 4.86 0 100.00
2 INT329679 CBX7 Regulation of CDKN2A 1 0.31 4.18 0 100.00
3 INT305281 Obsty1 Regulation of Localization of Gopc 1 0.02 1.49 0 100.00
4 INT305259 Binding of Car2 and Obsty1 1 0.02 1.2 0 100.00
5 INT305280 Lep Positive_regulation of Gene_expression of Leprot 1 0.07 1.03 0 100.00
6 INT305269 Lep Positive_regulation of Phosphorylation of Stat3 1 0.40 1.03 0 100.00
7 INT305267 Lep Regulation of Obsty1 1 0.04 0.97 0 100.00
8 INT305265 Obsty1 Negative_regulation of Phosphorylation of Nos3 1 0.05 0.78 0 100.00
9 INT329680 BMI1 Negative_regulation of Gene_expression of CDKN2A 1 0.15 1.14 0 100.00
10 INT243118 amd Regulation of Rpe 1 0.20 1.16 0 100.00
11 INT131809 Nfkb1 Positive_regulation of Gene_expression of Ptgs1 1 0.12 0.73 0.48 99.92
12 INT305253 Obsty1 Negative_regulation of Phosphorylation of Akt1 1 0.04 2.36 0 99.90
13 INT305252 Obsty1 Positive_regulation of Mapk8 1 0.05 1.52 0 99.90
14 INT305255 Obsty1 Positive_regulation of Phosphorylation of Akt1 1 0.05 2.09 0 99.90
15 INT349274 Binding of CGF1 and NOS1 1 0.00 2.97 0.12 99.80
16 INT342732 Arrd1 Negative_regulation of da 1 0.00 0.72 0.16 99.56
17 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69 99.48
18 INT305263 Obsty1 Regulation of Phosphorylation of Prkag1 1 0.01 0.78 0 99.48
19 INT305260 Obsty1 Regulation of Prkag1 1 0.01 0.78 0 99.48
20 INT281881 Binding of Aco1 and Ros1 1 0.01 1.93 0.1 99.48
21 INT258812 Sugt1 Positive_regulation of Ace 1 0.05 1.26 0.16 99.44
22 INT305257 Obsty1 Regulation of Gene_expression of Mapk1 1 0.03 2.05 0.08 99.40
23 INT305276 Obsty1 Regulation of Phosphorylation of Mapk1 1 0.02 1.11 0 99.40
24 INT305258 Lep Regulation of Gene_expression of Stat3 1 0.24 0.92 0 99.40
25 INT201274 Car2 Regulation of Gene_expression of Nos1 1 0.05 1.15 0.38 99.40
26 INT314680 Positive_regulation of TBX2 Negative_regulation of CDKN2A 1 0.34 1.16 0 99.36
27 INT314685 TBX2 Negative_regulation of CDKN2A 1 0.32 1.16 0 99.36
28 INT339045 Binding of RENBP and SNRNP70 1 0.01 0.38 0 99.24
29 INT339046 Binding of RENBP and SUGT1 1 0.00 0.38 0 99.24
30 INT246469 Binding of IGF1 and Gh 1 0.03 0.2 0 99.16
31 INT303857 DDR1 Positive_regulation of IL8 1 0.05 1.5 0.42 99.00
32 INT303858 DDR1 Positive_regulation of CXCR2 1 0.11 1.5 0.42 99.00
33 INT321404 Positive_regulation of MAP3K5 Positive_regulation of Gene_expression of SERPINE1 1 0.02 2.2 0.12 98.84
34 INT276211 Pdpk1 Regulation of Akt1 1 0.07 0.72 0.04 98.80
35 INT332285 Binding of KLRD1 and CRLF1 1 0.00 1.71 0.14 98.76
36 INT259716 Loxl1 Regulation of Loxl1 1 0.00 1.84 0.08 98.72
37 INT340293 Binding of Ins1 and Sirt1 1 0.25 1.25 0.05 98.72
38 INT325428 Csf2 Regulation of Mapt 1 0.08 1.47 0 98.72
39 INT305256 Binding of Car2 and Lipo2 1 0.01 0.89 0 98.66
40 INT337637 SIRT1 Negative_regulation of TP53 1 0.23 1.49 0 98.44
41 INT42262 Pomc Positive_regulation of POMC 1 0.21 0.35 0.24 98.32
42 INT297972 MAPK14 Negative_regulation of ING5 1 0.21 1.67 0.33 98.24
43 INT297965 MAPK14 Negative_regulation of GADD45A 1 0.05 1 0.21 98.24
44 INT297967 MAPK14 Negative_regulation of SCUBE3 1 0.01 0.67 0.12 98.24
45 INT338971 ING1 Regulation of TP53 1 0.09 1.02 0 98.16
46 INT240616 Binding of SHBG and ADIPOQ 1 0.31 4.43 0.37 98.12
47 INT276216 Binding of Akt1 and Ins1 2 0.03 2.61 0.4 98.08
48 INT295263 Tlr4 Positive_regulation of Trib3 1 0.18 0.66 0.04 98.08
49 INT105970 GH1 Regulation of Ghsr 1 0.04 1.16 0.84 97.92
50 INT105971 GH1 Regulation of Ghrl 1 0.03 0.75 0.52 97.92
51 INT105966 GH1 Regulation of GHS 1 0.03 0.37 0.25 97.92
52 INT210953 Binding of VEGFA and Csf2 1 0.00 0.47 0.3 97.68
53 INT232896 Krt8 Negative_regulation of Binding of ABR 1 0.04 0.68 0 97.68
54 INT119268 CDKN1A Regulation of CREBBP 1 0.21 0.44 0.07 97.66
55 INT119266 CDKN1A Regulation of EP300 1 0.47 0.44 0.07 97.66
56 INT311535 ROS1 Negative_regulation of CA2 1 0.19 0.61 0.04 97.64
57 INT174561 Binding of Cd28 and Ncl 1 0.00 0.62 0.07 97.44
58 INT305277 Positive_regulation of Binding of Lep and Obsty1 1 0.08 0.93 0 97.40
59 INT170459 Binding of CD1A and GOPC 1 0.07 0.1 0 97.36
60 INT323152 Binding of DBT and ESR1 2 0.02 1.29 0.27 97.32
61 INT311911 Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23 97.28
62 INT311908 Acvrl1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23 97.28
63 INT232899 Krt18 Negative_regulation of Binding of ABR 1 0.05 0.68 0 97.24
64 INT270199 Icos Positive_regulation of Localization of Il10 1 0.03 0.63 0.06 96.96
65 INT305264 Positive_regulation of Binding of Lep and Leprot 1 0.08 0.93 0 96.96
66 INT305273 Binding of Lep and Leprot 1 0.06 0.92 0 96.96
67 INT100609 Gnrhr Regulation of Cyp2c22 1 0.02 0.19 0 96.88
68 INT246466 GHS Positive_regulation of GHS Regulation of Gh 1 0.01 0.6 0.1 96.80
69 INT246468 GHS Regulation of Gh 1 0.05 1.12 0.19 96.48
70 INT246467 GHS Regulation of Localization of Gh 1 0.03 0.52 0.09 96.44
71 INT238802 Binding of Ager and Renbp 6 0.02 6.46 0.22 96.36
72 INT305266 Obsty1 Negative_regulation of Phosphorylation of Mapk14 1 0.03 1.05 0 96.28
73 INT348924 Mmp1 Regulation of Gene_expression of Renbp 1 0.03 0.95 0.26 96.24
74 INT225775 Enpp1 Positive_regulation of Ppi-rs 1 0.06 2.49 0.44 96.20
75 INT225776 Enpp1 Positive_regulation of Positive_regulation of Ppi-rs 1 0.08 1.67 0.28 96.20
76 INT269769 Gh Regulation of Gene_expression of Igf1 1 0.04 0.98 0 96.12
77 INT60022 Oprl1 Positive_regulation of Localization of Rhd 1 0.18 0.1 0.44 96.04
78 INT204943 Il6 Regulation of Slc39a14 1 0.00 0.54 0.36 95.76
79 INT308660 Binding of Ager and App 1 0.08 1.22 0.12 95.52
80 INT313463 Ppp2ca Regulation of Syp 1 0.43 0.6 0.06 95.48
81 INT313450 Th Regulation of Syp 1 0.32 0.6 0.06 95.48
82 INT337639 TP53 Regulation of Gene_expression of MIR34A 1 0.08 1.19 0 95.20
83 INT269060 Il6 Positive_regulation of Cybb 1 0.75 0.65 0.26 94.96
84 INT305254 Obsty1 Regulation of Gene_expression of Nos3 1 0.03 0.97 0 94.80
85 INT305262 Obsty1 Positive_regulation of Phosphorylation of Nos3 1 0.05 0.96 0 94.80
86 INT313446 Syp Regulation of Ppp2ca 1 0.58 0.62 0.26 94.76
87 INT352519 INS Positive_regulation of Localization of Slc2a4 1 0.07 0.97 0.03 94.72
88 INT353197 ARNTL Regulation of Hlf 1 0.29 0.33 0 94.52
89 INT353195 ARNTL Regulation of Gene_expression of Tef 1 0.22 0.33 0 94.52
90 INT353196 ARNTL Regulation of Tef 1 0.36 0.32 0 94.52
91 INT353198 ARNTL Regulation of Dbp 1 0.32 0.32 0 94.52
92 INT353194 ARNTL Regulation of Localization of Ahr 1 0.27 0.32 0 94.52
93 INT267156 Binding of VDR and SUGT1 1 0.04 3.4 0.09 94.40
94 INT313435 Syp Regulation of Th 1 0.43 1.6 0.64 94.40
95 INT313468 Negative_regulation of Syp Regulation of Th 1 0.30 0.3 0.03 94.40
96 INT327451 HTN1 Positive_regulation of Adra1a 1 0.00 1.36 0.03 94.32
97 INT311265 RENBP Regulation of IL8 1 0.03 1.59 0.33 94.28
98 INT311263 RENBP Regulation of TNF 1 0.01 1.59 0.33 94.28
99 INT311266 RENBP Regulation of IL6 1 0.02 1.59 0.32 94.28
100 INT292893 TNF Regulation of IL8 2 0.27 1.3 0.63 94.28
101 INT267585 TNF Regulation of IL6 2 0.16 2.44 0.37 94.28
102 INT311268 RENBP Regulation of Gene_expression of IL8 1 0.02 1.05 0.24 94.28
103 INT311267 RENBP Regulation of Gene_expression of TNF 1 0.02 0.54 0.09 94.12
104 INT305278 Lep Negative_regulation of Obsty1 1 0.07 0.94 0 94.08
105 INT225778 Igf1 Negative_regulation of Positive_regulation of Ppi-rs 1 0.01 0.82 0.14 94.08
106 INT243120 Binding of amd and Rpe 1 0.26 1.18 0 94.04
107 INT266407 Binding of ALB and Ager 1 0.00 1.42 0 94.00
108 INT266409 Binding of ALB and Renbp 1 0.00 1.41 0 94.00
109 INT325433 Binding of Csf2 and Mapt 1 0.12 4.41 0 93.92
110 INT329429 Binding of Col7a1 and Hmgcr 1 0.01 0.28 0.06 93.92
111 INT291545 Binding of Dlat and St8sia2 1 0.14 0.44 0.37 93.84
112 INT305274 Obsty1 Regulation of Gene_expression of Prkag1 1 0.01 0.94 0.08 93.72
113 INT201755 ROS1 Positive_regulation of Casp3 1 0.00 1.4 0 93.72
114 INT340131 Binding of Fcgrt and Igh-VS107 1 0.29 0.63 0 93.44
115 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76 93.40
116 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34 93.12
117 INT328303 Gene_expression of GHS Positive_regulation of Gene_expression of GHRH 1 0.09 0.19 0.04 93.12
118 INT307212 Ide Regulation of Lep 1 0.00 0.51 0 92.64
119 INT305268 Obsty1 Positive_regulation of Lipo2 1 0.00 0.93 0 92.56
120 INT311524 Gnrhr Positive_regulation of Transcription of Grin2a 1 0.02 0.54 0.55 92.32
121 INT311521 Gnrhr Positive_regulation of Gene_expression of Gria1 1 0.00 0.54 0.54 92.32
122 INT311522 Gnrhr Positive_regulation of Transcription of Gria1 1 0.00 0.54 0.54 92.32
123 INT325431 Positive_regulation of Binding of Csf2 and Mapt 1 0.18 1.49 0 92.32
124 INT315221 Tpt1 Regulation of Positive_regulation of Trp53 1 0.33 1.04 0 92.00
125 INT308659 Binding of Ager and ecs 1 0.01 1.14 0.12 91.96
126 INT305986 Binding of Nfe2l2 and Cul3 1 0.39 0.44 0 91.04
127 INT183785 INS Positive_regulation of Gene_expression of NFKBIB 1 0.03 1.83 0.34 90.96
128 INT171991 Binding of DMD and ERAL1 1 0.01 0.54 0 90.76
129 INT311918 Insrr Negative_regulation of Tgfbr1 1 0.00 0.87 0.26 90.72
130 INT311902 Acvrl1 Negative_regulation of Tgfbr1 1 0.13 0.87 0.26 90.72
131 INT311900 Acvrl1 Negative_regulation of Insrr 1 0.00 0.86 0.25 90.68
132 INT184704 Binding of Prrx2 and Sr1 1 0.21 1.65 0.13 90.56
133 INT201273 Nos2 Regulation of Nos1 1 0.17 0.99 0.23 90.32
134 INT253417 ATIC Positive_regulation of Prkaa2 1 0.02 0.31 0.04 90.24
135 INT275756 xn Regulation of Ins1 1 0.01 3.25 0 90.16
136 INT270759 Binding of HSD11B1 and TERT 1 0.07 1.67 0 90.08
137 INT189151 MTNR1B Positive_regulation of Gene_expression of IL6 1 0.01 0.35 0.47 89.96
138 INT189145 MTNR1B Positive_regulation of Gene_expression of IL2 1 0.02 0.3 0.26 89.96
139 INT189142 MTNR1B Positive_regulation of Gene_expression of IL12A 1 0.01 0.29 0.24 89.96
140 INT342356 Arrd1 Positive_regulation of Negative_regulation of Ppara 1 0.01 0.81 0.04 89.84
141 INT355542 Binding of XRCC3 and BCC1 1 0.00 1.19 0.07 89.80
142 INT262815 Gene_expression of Serpinf1 Negative_regulation of Gene_expression of Gfap 1 0.39 2.73 0.44 89.76
143 INT285939 IL6 Positive_regulation of TEP1 1 0.01 1.76 0.61 89.68
144 INT318218 SIRT1 Positive_regulation of Binding of FOXO3 1 0.44 0.51 0 89.24
145 INT318221 SIRT1 Positive_regulation of FOXO3 1 0.41 0.63 0 89.24
146 INT318216 SIRT1 Positive_regulation of Gene_expression of FOXO3 1 0.36 0.52 0 89.24
147 INT270203 Binding of CD28 and Apc 1 0.04 0.58 0.08 89.20
148 INT270197 Binding of Apc and Cd86 1 0.02 0.58 0.08 89.20
149 INT270198 Binding of Apc and Cd80 1 0.02 0.58 0.08 89.20
150 INT183784 INS Negative_regulation of Binding of TBK1 1 0.01 1.81 0.34 89.04
151 INT270201 Binding of CD28 and Cd86 1 0.10 0.58 0.08 88.64
152 INT239181 Gene_expression of Gh Negative_regulation of Sod1 1 0.24 0.33 0 88.48
153 INT239182 Gene_expression of Gh Negative_regulation of Cat 1 0.17 0.33 0 88.48
154 INT183783 INS Negative_regulation of TBK1 1 0.01 1.81 0.34 88.40
155 INT183782 INS Negative_regulation of Gene_expression of TBK1 1 0.01 1.81 0.34 88.40
156 INT248387 CHD5 Regulation of Gene_expression of TP53 1 0.20 0.83 0 88.20
157 INT317310 Binding of Large and Psmb10 1 0.00 0.94 0.03 88.08
158 INT270202 Binding of CD28 and Cd80 1 0.09 0.58 0.08 87.92
159 INT278242 MSC Regulation of Gene_expression of Cd36 1 0.08 1.17 0 87.92
160 INT332684 Binding of Edn1 and Lep 1 0.09 1.11 0.04 87.84
161 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77 87.52
162 INT246478 Binding of SERPINE1 and ANGPTL5 1 0.01 1.32 0.1 87.28
163 INT270355 Vcsa1 Positive_regulation of Negative_regulation of Mme 1 0.13 0.52 0.12 87.28
164 INT340568 Fgf1 Positive_regulation of Mapk1 1 0.06 1.02 0.04 87.04
165 INT342355 Arrd1 Positive_regulation of Osbpl1a 1 0.01 0.8 0.04 86.88
166 INT183780 INS Negative_regulation of Gene_expression of CYBB 1 0.02 1.74 0.34 86.56
167 INT262617 Ager Positive_regulation of Rpe 1 0.00 0.81 0 86.48
168 INT262620 Renbp Positive_regulation of Ager Positive_regulation of Rpe 1 0.00 0.81 0 86.48
169 INT25501 Gnrhr Positive_regulation of Igf1 1 0.12 0.09 0.1 86.32
170 INT200536 Ca2 Positive_regulation of NOS1 1 0.03 0.74 0.07 86.16
171 INT352269 Binding of Jund and Adora1 1 0.15 1.2 1.25 86.08
172 INT342359 Arrd1 Positive_regulation of Scd1 1 0.01 0.8 0.04 85.92
173 INT318222 GADD45A Regulation of FOXO3 1 0.16 0.52 0 85.72
174 INT312550 DAK Positive_regulation of Rxra 1 0.00 1.48 0.18 85.68
175 INT312519 DAK Positive_regulation of PPARA 1 0.00 1.46 0.18 85.68
176 INT156970 Negative_regulation of Kcnip3 Positive_regulation of Transcription of Creb1 1 0.47 0.45 0.17 85.36
177 INT297733 Cbr1 Regulation of Gene_expression of Bcl2 1 0.05 0.94 0.07 85.36
178 INT290496 Binding of FANCB and Fcgrt 1 0.22 0.17 0 85.36
179 INT324342 UMOD Positive_regulation of Scr 1 0.17 1.29 0 85.24
180 INT324346 Regulation of UMOD Positive_regulation of Scr 1 0.10 1.31 0 85.24
181 INT308647 Ager Positive_regulation of Gene_expression of Bace1 1 0.09 1.01 0.12 85.08
182 INT184955 EGR1 Regulation of Regulation of TGFB1 1 0.39 0.3 0 84.92
183 INT330120 Bdkrb2 Regulation of Bdkrb1 1 0.19 1.26 0.38 84.88
184 INT352614 Negative_regulation of Binding of Mdm2 and Trp53 1 0.19 1.16 0 84.56
185 INT262819 Gene_expression of Serpinf1 Negative_regulation of Binding of 1190002H23Rik 1 0.05 2.66 0.43 84.48
186 INT242015 Binding of Mdm2 and Trp53 3 0.16 5.74 0 84.04
187 INT69032 IL18 Positive_regulation of IFNA1 12 0.23 7.87 3.83 83.84
188 INT246480 Binding of ALB and SHBG 2 0.14 1.45 0.03 83.60
189 INT239185 Binding of Clk1 and Shc1 1 0.04 2.42 0 83.56
190 INT305279 Lep Regulation of Gene_expression of Akt1 1 0.18 0.83 0 83.52
191 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72 83.52
192 INT352617 Mdm2 Positive_regulation of Positive_regulation of Trp53 1 0.20 2.56 0 83.40
193 INT289530 Sirt1 Regulation of Foxo1 1 0.25 0.42 0 82.96
194 INT201728 Ntrk1 Regulation of Transcription of App 1 0.03 0.39 0.15 82.72
195 INT217651 Binding of ROS1 and fa 1 0.01 1.09 0.07 82.64
196 INT352518 Binding of FAT1 and Adipoq 1 0.01 2.79 0.2 82.20
197 INT352517 Binding of INS and Adipoq 1 0.09 1.32 0.07 82.20
198 INT320352 Pnp Positive_regulation of Ighg2b 1 0.03 0.08 0 82.08
199 INT183793 INS Negative_regulation of Binding of Ros1 1 0.16 1.66 0.34 81.92
200 INT54930 Gnrhr Regulation of Gene_expression of Ghrh 1 0.10 0.16 0.34 81.92

Single Events

The table below shows the top 200 pain related interactions that have been reported for Aging. They are ordered first by their pain relevance and then by number of times they were reported in Aging. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT153666 Gene_expression of CAV1 156 0.77 120.99 3.9 100.00
2 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 100.00
3 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 100.00
4 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 100.00
5 INT214005 Gene_expression of Ank2 1 0.78 29.4 1.88 100.00
6 INT329686 Gene_expression of CBX7 1 0.77 54.06 0.45 100.00
7 INT10841 Positive_regulation of Gene_expression of Gh 101 0.59 45.39 16.96 100.00
8 INT92515 Gene_expression of Grin2a 84 0.76 26.68 38.37 100.00
9 INT153670 Positive_regulation of Gene_expression of CAV1 26 0.69 44.27 0.92 100.00
10 INT116428 Gene_expression of Cybb 68 0.76 35.81 7.07 100.00
11 INT305247 Gene_expression of Obsty1 1 0.11 11.21 0.11 100.00
12 INT305242 Binding of Obsty1 1 0.07 9.33 0.17 100.00
13 INT76342 Positive_regulation of Gene_expression of Alox5 9 0.56 5.29 2.87 100.00
14 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 100.00
15 INT108690 Gene_expression of Hcn1 19 0.76 7.2 8 100.00
16 INT231293 Negative_regulation of Grin2d 4 0.45 3.95 3.38 100.00
17 INT14865 Regulation of Prep 20 0.55 4.21 6.75 100.00
18 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 100.00
19 INT321428 Positive_regulation of Positive_regulation of MAP3K5 1 0.13 4.65 0.25 100.00
20 INT14572 Binding of INS 205 0.48 175.43 13.38 100.00
21 INT329694 Negative_regulation of Gene_expression of CBX7 1 0.58 8.06 0.14 100.00
22 INT5128 Positive_regulation of Lhb 232 0.69 44.23 71.26 100.00
23 INT124938 Gene_expression of MTNR1B 15 0.15 3.63 1.72 100.00
24 INT305236 Phosphorylation of Obsty1 1 0.12 2.77 0.16 100.00
25 INT64193 Regulation of Grin2a 19 0.54 2.98 10.31 100.00
26 INT75505 Regulation of Gene_expression of CDKN1A 24 0.60 12.24 3.07 100.00
27 INT184677 Negative_regulation of Spaca4 2 0.02 3.19 0.91 100.00
28 INT209221 Regulation of Gene_expression of Grin2a 5 0.24 2.81 3.45 100.00
29 INT305228 Positive_regulation of Obsty1 1 0.07 4.12 0 100.00
30 INT203646 Gene_expression of STIP1 26 0.63 23.57 1.14 100.00
31 INT289550 Positive_regulation of Sirt1 25 0.69 13.59 0.8 100.00
32 INT65892 Negative_regulation of Binding of Gh 8 0.32 3.61 1.38 100.00
33 INT117642 Regulation of Gene_expression of Grin1 18 0.53 7.09 8.08 100.00
34 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
35 INT97519 Binding of WRN 2 0.27 1.92 0.14 100.00
36 INT771 Regulation of Nts 93 0.61 13.13 53.57 100.00
37 INT72380 Positive_regulation of Shc1 10 0.69 6.87 0.77 100.00
38 INT23606 Regulation of Atp2b4 10 0.25 3.33 1.63 100.00
39 INT248400 Regulation of CDKN1C 1 0.45 2.92 0.17 100.00
40 INT251079 Gene_expression of G0s2 32 0.77 36.32 2.01 100.00
41 INT305238 Positive_regulation of Gene_expression of Obsty1 1 0.07 1.3 0 100.00
42 INT101189 Transcription of Gtf3a 49 0.17 24.39 7.93 100.00
43 INT56524 Gene_expression of Grip2 67 0.74 14.77 26.23 100.00
44 INT125534 Regulation of Tg(CAG-EGFP)D4Nagy 31 0.39 13.88 5.58 100.00
45 INT311509 Regulation of Transcription of Grin2a 1 0.13 0.42 0.27 100.00
46 INT117212 Gene_expression of Hcn2 13 0.78 5.83 8.19 100.00
47 INT84599 Gene_expression of Aqp2 31 0.77 22.58 2.54 100.00
48 INT73553 Gene_expression of Aqp1 23 0.67 4.65 1.34 100.00
49 INT225765 Regulation of Gene_expression of Cilp 1 0.25 1.57 0.15 100.00
50 INT73359 Gene_expression of GLB1 8 0.75 3.18 1.92 100.00
51 INT311516 Regulation of Localization of Grin2d 2 0.32 0.62 0.51 100.00
52 INT177581 Regulation of Fig4 113 0.41 39.26 27.75 100.00
53 INT111451 Regulation of ADIPOQ 24 0.56 18.81 2.47 100.00
54 INT240141 Gene_expression of MAPK10 4 0.25 1.82 0.18 100.00
55 INT352377 Positive_regulation of Sirt4 1 0.36 1.64 0.04 100.00
56 INT352376 Positive_regulation of Sirt3 1 0.37 1.64 0.04 100.00
57 INT50080 Binding of APOE 38 0.45 29.61 2.67 100.00
58 INT168658 Regulation of Gene_expression of HTR1B 2 0.44 2.11 2.44 100.00
59 INT344774 Transcription of CD200 1 0.10 0.9 0.11 100.00
60 INT22781 Binding of COL7A1 76 0.48 41.59 6.66 100.00
61 INT344773 Transcription of CFI 1 0.10 0.89 0.11 100.00
62 INT28020 Binding of Adipoq 10 0.36 11.49 0.77 100.00
63 INT215814 Negative_regulation of Gene_expression of Aqp1 2 0.31 0.25 0.17 100.00
64 INT247883 Negative_regulation of Gene_expression of Aqp3 1 0.34 0.56 0.05 100.00
65 INT75627 Gene_expression of Mapt 41 0.75 22.1 4.58 100.00
66 INT251078 Positive_regulation of Gene_expression of G0s2 8 0.69 8.1 0.57 100.00
67 INT352375 Positive_regulation of Nampt 1 0.21 1.32 0.05 100.00
68 INT297904 Positive_regulation of Foxo3 6 0.57 8.19 0.29 100.00
69 INT289592 Positive_regulation of Foxo1 2 0.41 1.44 0.04 100.00
70 INT117014 Binding of TCN2 11 0.13 1.6 1.38 100.00
71 INT74253 Binding of Magt1 2 0.09 0.49 0.12 100.00
72 INT71868 Regulation of Tenc1 9 0.52 10.73 4.09 100.00
73 INT195204 Regulation of Gene_expression of Tenc1 3 0.25 2.37 0.09 100.00
74 INT153349 Binding of Bcl2l10 1 0.07 1.38 0.15 100.00
75 INT195202 Negative_regulation of Gene_expression of Tenc1 7 0.24 3.76 0.62 100.00
76 INT26973 Gene_expression of Tenc1 59 0.66 27.19 12 100.00
77 INT7034 Regulation of Regulation of CGA 5 0.16 0.17 2.29 100.00
78 INT349280 Positive_regulation of Positive_regulation of CGF1 1 0.10 1.18 0.05 100.00
79 INT50636 Regulation of Tac4 9 0.53 0.33 3.1 100.00
80 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52 100.00
81 INT6196 Regulation of Nppa 83 0.62 30.31 30.18 100.00
82 INT7039 Regulation of Nkx1-1 22 0.44 10.51 20.89 100.00
83 INT159328 Localization of EPC1 11 0.59 7.08 1.14 100.00
84 INT251661 Phosphorylation of NT5E 2 0.21 1.59 0.46 100.00
85 INT176501 Binding of KLK5 2 0.23 0.17 0.14 100.00
86 INT10884 Regulation of Cyp2j3 1 0.13 0.17 0.08 100.00
87 INT299973 Binding of FTSJ3 1 0.04 2.6 0.04 100.00
88 INT299977 Negative_regulation of Localization of EPC1 1 0.16 1.34 0.03 100.00
89 INT317280 Negative_regulation of Gene_expression of Psmb10 1 0.00 0.9 0 100.00
90 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 99.98
91 INT74365 Positive_regulation of Alox5 19 0.47 11.03 4.04 99.98
92 INT26534 Regulation of Akt1 34 0.61 14.47 11.86 99.98
93 INT208291 Negative_regulation of Pten 2 0.44 5.42 3.36 99.98
94 INT184692 Positive_regulation of 10S 1 0.02 4.47 1.01 99.98
95 INT17421 Negative_regulation of Alox5 41 0.57 15.23 10.05 99.98
96 INT39229 Regulation of Alox5 6 0.57 3.2 1.72 99.98
97 INT184698 Positive_regulation of Prrx2 1 0.38 3.21 1.01 99.98
98 INT7813 Regulation of SRI 25 0.61 6.18 8.13 99.98
99 INT261602 Positive_regulation of Binding of Il6 2 0.50 1.75 0.62 99.98
100 INT168654 Negative_regulation of Transcription of Vip 1 0.13 0.51 0.78 99.98
101 INT139976 Regulation of Tp53 7 0.44 6.49 0.39 99.98
102 INT291679 Regulation of Transcription of Alox5 1 0.25 0.94 0.28 99.98
103 INT8824 Regulation of Vip 95 0.62 15.7 43.63 99.98
104 INT39587 Gene_expression of CP 42 0.65 31.48 11.87 99.98
105 INT34476 Regulation of Regulation of Cck 3 0.34 0.71 3.78 99.98
106 INT168657 Negative_regulation of Transcription of Grp 1 0.02 0.26 0.58 99.98
107 INT168660 Negative_regulation of Gene_expression of SRI 2 0.04 0.26 0.51 99.98
108 INT11948 Negative_regulation of Gene_expression of Vip 9 0.43 2.8 1.54 99.98
109 INT103942 Binding of BPHL 11 0.30 14.26 0.53 99.98
110 INT94412 Negative_regulation of Positive_regulation of ADRB3 3 0.38 0.52 0.55 99.98
111 INT48240 Binding of Ngf 46 0.46 23.51 24.42 99.98
112 INT11157 Binding of EGF 88 0.48 53.73 21.25 99.98
113 INT34860 Negative_regulation of Gene_expression of Scn2a1 8 0.30 0.97 1.94 99.98
114 INT3521 Regulation of Csf2 38 0.54 11.09 12.73 99.98
115 INT29708 Gene_expression of Gria1 177 0.78 56.36 77.37 99.96
116 INT108433 Negative_regulation of Mat1a 16 0.57 14.15 2.82 99.96
117 INT101008 Gene_expression of Scn5a 5 0.75 26.93 6.06 99.96
118 INT1499 Negative_regulation of Gene_expression of Gh 58 0.42 25.17 7.86 99.96
119 INT25123 Negative_regulation of COL7A1 42 0.58 19.98 5.96 99.96
120 INT215851 Positive_regulation of Gene_expression of Cyp2b10 2 0.22 2.92 0.18 99.96
121 INT269767 Positive_regulation of Localization of Pappa 1 0.49 1.88 0 99.96
122 INT144700 Gene_expression of Kras 21 0.41 12.28 0.57 99.96
123 INT183399 Gene_expression of Cyp2b10 17 0.39 18.39 0.71 99.96
124 INT322433 Regulation of CGF1 8 0.12 5.94 0.37 99.96
125 INT14560 Regulation of Igf1 41 0.59 19.59 6.3 99.96
126 INT333339 Positive_regulation of CGF1 2 0.10 4.99 0.13 99.96
127 INT239154 Gene_expression of Kl 1 0.57 2.79 0.04 99.96
128 INT270150 Positive_regulation of Positive_regulation of Irak1 3 0.25 0.91 0.09 99.96
129 INT3535 Regulation of CA2 61 0.32 16.48 10.8 99.96
130 INT3217 Regulation of Ins1 154 0.62 87.11 27.29 99.96
131 INT213740 Positive_regulation of Epc1 14 0.25 9.8 1.07 99.96
132 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 99.92
133 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34 99.92
134 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45 99.92
135 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.92
136 INT49263 Binding of Grip2 31 0.41 9.86 16.38 99.92
137 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 99.92
138 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39 99.92
139 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22 99.92
140 INT2597 Negative_regulation of ACHE 82 0.59 46.36 8.62 99.92
141 INT28122 Gene_expression of MSC 111 0.58 26.83 6.57 99.92
142 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43 99.92
143 INT144701 Gene_expression of Cdkn2a 15 0.75 8.42 0.53 99.92
144 INT249747 Gene_expression of Sirt3 1 0.17 2.48 0 99.92
145 INT197493 Localization of Apoe 61 0.79 27.48 7.06 99.92
146 INT231297 Localization of Grin2d 8 0.71 1.25 2.36 99.92
147 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 99.92
148 INT55091 Positive_regulation of Mgst1 35 0.69 10.77 6.88 99.92
149 INT77925 Negative_regulation of TEP1 21 0.53 15.23 2.62 99.92
150 INT174688 Binding of Tlr2 45 0.42 36.65 5.25 99.92
151 INT738 Regulation of POMC 459 0.62 111.19 243.74 99.92
152 INT125066 Negative_regulation of HDAC4 56 0.49 41.55 5.42 99.92
153 INT12488 Binding of Morph3 2 0.01 0.41 1.24 99.92
154 INT9895 Binding of GHR 18 0.36 4.8 5.65 99.92
155 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 99.92
156 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76 99.90
157 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 99.90
158 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21 99.88
159 INT214 Localization of AVP 370 0.81 208.51 91.09 99.88
160 INT943 Negative_regulation of Cck 205 0.59 38.42 174.78 99.88
161 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 99.86
162 INT182830 Negative_regulation of Protein_catabolism of APP 2 0.35 2.09 0.03 99.86
163 INT1893 Localization of Gh 1041 0.79 340.23 256.58 99.84
164 INT32794 Gene_expression of Grin2d 81 0.68 20.87 26.99 99.84
165 INT158 Localization of Prl 2431 0.81 378.96 952.2 99.84
166 INT34552 Regulation of Gene_expression of Alox5 3 0.50 5.06 1.75 99.84
167 INT151588 Phosphorylation of Prkag1 48 0.73 15.62 1.38 99.84
168 INT252 Localization of GH1 529 0.80 227.4 122.05 99.84
169 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43 99.84
170 INT126577 Gene_expression of Ppi-rs 25 0.14 19.1 2.74 99.84
171 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46 99.84
172 INT303962 Phosphorylation of Lep 2 0.80 5.2 0.31 99.84
173 INT49001 Regulation of Gria1 51 0.56 18.28 31.22 99.84
174 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 99.84
175 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 99.84
176 INT25451 Negative_regulation of Gfm1 13 0.27 8.22 1.06 99.84
177 INT160853 Gene_expression of Syp 87 0.72 20.06 5.31 99.84
178 INT1652 Regulation of Pomc 387 0.62 61.01 186.51 99.84
179 INT305226 Negative_regulation of Phosphorylation of Lep 1 0.42 1.89 0 99.84
180 INT1200 Negative_regulation of Ins1 274 0.58 155.17 56.14 99.84
181 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35 99.84
182 INT34678 Regulation of Negative_regulation of Pomc 8 0.62 1.24 3.47 99.84
183 INT8088 Regulation of Localization of Cga 28 0.60 2.37 13.91 99.84
184 INT2165 Localization of Cga 41 0.80 4.02 19.53 99.84
185 INT10131 Gene_expression of Serpinf1 53 0.76 35.57 6.42 99.84
186 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 99.84
187 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 99.84
188 INT129962 Positive_regulation of Gene_expression of MMP13 41 0.65 20.74 8.54 99.84
189 INT219 Negative_regulation of Th 55 0.59 20.88 17.09 99.84
190 INT5617 Localization of Nppa 266 0.81 83.51 83.89 99.84
191 INT48924 Positive_regulation of Mapk3 107 0.67 50.53 34.05 99.84
192 INT306088 Localization of ADH5 1 0.14 0.74 0.11 99.84
193 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 99.84
194 INT340878 Positive_regulation of Hspb7 1 0.31 0.78 0 99.84
195 INT174687 Regulation of Positive_regulation of Il6 10 0.61 9.07 2.61 99.84
196 INT3392 Negative_regulation of Sst 23 0.59 8.21 15.82 99.84
197 INT5338 Regulation of Npy 92 0.62 25.54 51.24 99.84
198 INT7561 Positive_regulation of gr 70 0.57 31.92 20.22 99.84
199 INT53202 Negative_regulation of Positive_regulation of gr 6 0.46 2.35 2.27 99.84
200 INT2910 Regulation of Abat 169 0.62 36.95 153.53 99.84
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