D:Airway Remodeling

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Disease Term
Synonyms Airway Remodeling Asthmatic, Airway Remodeling Small, Airway Remodelings, AIRWAY REMODELINGS ASTHMATIC, AIRWAY REMODELINGS SMALL, AIRWAY REMODELLING, Airway Remodelling Asthmatic, Airway Remodelling Small, Airway Remodellings, Airway Remodellings Asthmatic, AIRWAY REMODELLINGS SMALL
Documents 71
Hot Single Events 190
Hot Interactions 23

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Airway Remodeling. They are ordered first by their relevance to Airway Remodeling and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT186769 Dep1 Positive_regulation of Gene_expression of IgG 2 0.03 1.3 0.36 98.12
2 INT311872 IGHE Positive_regulation of Localization of Mmp9 1 0.01 1.35 0.22 95.64
3 INT183695 Binding of Tlr3 and Ducm1 1 0.04 2.75 0.56 91.56
4 INT183700 Binding of Pilra and Ducm1 1 0.00 2.35 0.53 91.56
5 INT323027 Binding of Il9 and Gtf3a 1 0.03 0.66 0.03 90.20
6 INT170991 FGF2 Positive_regulation of Gene_expression of TIMP1 1 0.01 0.72 0.13 88.64
7 INT332250 Stat6 Positive_regulation of Gene_expression of Pdgfa 1 0.05 1.33 0.12 88.52
8 INT332252 Stat6 Positive_regulation of Gene_expression of Il13 1 0.08 1.32 0.12 88.52
9 INT193035 Positive_regulation of PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21 87.40
10 INT193032 Positive_regulation of EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21 87.40
11 INT193025 PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21 87.08
12 INT193036 EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21 87.08
13 INT170992 Binding of FN1 and MMRN1 3 0.01 2.13 0.73 86.84
14 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88 86.72
15 INT271409 NGF Positive_regulation of TRPV1 1 0.08 2.45 0.94 86.72
16 INT271410 NGF Positive_regulation of Gene_expression of TRPV1 1 0.07 2.45 0.94 86.72
17 INT190183 MAPK1 Regulation of CDCP1 1 0.00 1.19 0.85 86.40
18 INT190168 BSG Regulation of CDCP1 1 0.00 1.18 0.84 86.20
19 INT190147 MMP12 Positive_regulation of MMP2 Positive_regulation of Protein_catabolism of MMRN1 1 0.03 0.87 0.9 86.08
20 INT338418 Il13 Positive_regulation of Gene_expression of Il9 1 0.07 1.24 0.3 85.44
21 INT332244 Il13 Positive_regulation of Gtf3a 1 0.01 1.21 0.15 85.20
22 INT190165 MMP12 Positive_regulation of MMP2 1 0.13 0.72 0.85 81.68
23 INT334498 Binding of IL13 and KLF1 1 0.00 0.63 0 81.32
24 INT332247 Egf Positive_regulation of Stat6 1 0.13 1.23 0.19 75.68
25 INT332251 Il13 Positive_regulation of Stat1 1 0.14 1.4 0.18 75.12
26 INT332245 Pdgfa Positive_regulation of Stat6 1 0.07 1.22 0.19 75.04
27 INT336637 Binding of PTPRC and Fn1 1 0.00 0.32 0 75.00
28 INT336636 Binding of Fbln1 and Fn1 1 0.14 0.32 0 75.00
29 INT336640 Binding of PTPRC and Fbln1 1 0.01 0.32 0 75.00
30 INT184120 Il4 Positive_regulation of Stat6 3 0.09 2.39 0.67 70.88
31 INT336634 Fbln1 Positive_regulation of Ecm1 1 0.06 1.26 0.09 70.36
32 INT332253 Il13 Positive_regulation of Stat6 1 0.08 1.18 0.19 70.16
33 INT336639 PTPRC Positive_regulation of Ecm1 1 0.00 0.62 0.04 69.12
34 INT336631 Binding of Fn1 and Fgg 1 0.00 0.59 0.04 67.16
35 INT336638 Binding of LAMB2 and Fn1 1 0.00 0.58 0.04 67.16
36 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76 65.12
37 INT190145 Binding of JUN and MMP12 Positive_regulation of Positive_regulation of PIK3CA 1 0.01 0.57 0.57 65.12
38 INT190146 Positive_regulation of PIK3CA Positive_regulation of Binding of JUN and MMP12 1 0.01 0.57 0.57 65.12
39 INT190148 Binding of JUN and MMP12 Positive_regulation of MMP12 1 0.33 0.57 0.57 65.12
40 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 63.48
41 INT338422 Il4 Positive_regulation of Gtf3a 1 0.00 0.75 0.13 62.48
42 INT338428 Il4 Positive_regulation of Gata3 1 0.06 0.75 0.13 62.48
43 INT190181 Positive_regulation of PIK3CA Positive_regulation of MMP12 1 0.01 0.54 0.56 61.44
44 INT334500 Binding of IGHE and SPARCL1 1 0.01 1.47 0.55 52.28
45 INT336632 Ecm1 Regulation of Regulation of Ahr 1 0.03 0.61 0.11 50.00
46 INT192263 LTC4S Positive_regulation of Gene_expression of TIMP1 1 0.00 0.28 0.04 50.00
47 INT274170 Il13 Regulation of Il4 3 0.09 2.75 0.51 45.20
48 INT274167 Il13 Regulation of Il5 2 0.09 2.05 0.59 44.96
49 INT292363 Rbmy1a1 Positive_regulation of Bhr1 1 0.05 1.04 0.12 42.80
50 INT344428 Il13 Positive_regulation of Gene_expression of Siglec5 1 0.27 0.46 0.21 38.92
51 INT294762 Il4 Regulation of Il13 2 0.09 0.92 0.32 25.00
52 INT344429 Siglec5 Regulation of Gene_expression of Fn1 1 0.11 0.65 0.18 25.00
53 INT344427 Il4 Regulation of Gene_expression of Siglec5 1 0.14 0.35 0.09 25.00
54 INT344433 Il13 Regulation of Gene_expression of Siglec5 1 0.18 0.35 0.09 25.00
55 INT274168 Egf Positive_regulation of Gene_expression of Muc5ac 1 0.01 2.11 0.17 24.76
56 INT334499 Binding of AMELX and IL4 1 0.12 0.47 0.29 19.04
57 INT193027 EGF Positive_regulation of Positive_regulation of MRGPRX1 1 0.02 0 0.27 16.52
58 INT69032 IL18 Positive_regulation of IFNA1 12 0.23 7.87 3.83 5.00
59 INT216736 Binding of ADORA2B and ATP6V0A1 2 0.08 0.06 0.93 5.00
60 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9 5.00
61 INT226337 Binding of IL10 and IL10RA 2 0.24 2.51 0.85 5.00
62 INT226340 Binding of CD4 and IFNA1 3 0.03 3.84 0.85 5.00
63 INT190182 JUN Positive_regulation of MMP12 1 0.34 0.08 0.8 5.00
64 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79 5.00
65 INT183698 Binding of Cxcr2 and Cxcl1 3 0.33 3.26 0.76 5.00
66 INT190174 TNF Positive_regulation of MMP12 1 0.27 0.08 0.74 5.00
67 INT190169 Regulation of JUN Positive_regulation of Localization of MMP12 1 0.30 0.07 0.74 5.00
68 INT237325 Il6 Positive_regulation of Gene_expression of Ik 2 0.00 2.09 0.72 5.00
69 INT226540 Binding of IL24 and Il20ra 1 0.00 0.97 0.71 5.00
70 INT190177 Gene_expression of IL13 Regulation of Gene_expression of IL4 1 0.04 0.05 0.68 5.00
71 INT190172 Gene_expression of IL13 Regulation of MMP12 1 0.12 0.05 0.68 5.00
72 INT190171 Gene_expression of IL4 Regulation of Gene_expression of IL13 1 0.04 0.05 0.68 5.00
73 INT190164 Gene_expression of IL4 Regulation of MMP12 1 0.11 0.05 0.68 5.00
74 INT194618 Il17a Positive_regulation of Gene_expression of IL8 2 0.01 1.94 0.67 5.00
75 INT190178 PIK3CG Regulation of MMP12 1 0.09 0 0.65 5.00
76 INT190211 Adm Regulation of MMP12 1 0.29 0 0.65 5.00
77 INT190170 IL4 Regulation of Gene_expression of IL13 1 0.04 0 0.62 5.00
78 INT190175 IL13 Regulation of Gene_expression of IL4 1 0.04 0 0.62 5.00
79 INT190180 IL4 Regulation of MMP12 1 0.11 0 0.6 5.00
80 INT190166 IL13 Regulation of MMP12 1 0.12 0 0.59 5.00
81 INT226360 IL18 Positive_regulation of Gene_expression of IL4 1 0.05 2.66 0.54 5.00
82 INT226348 IL18 Positive_regulation of Gene_expression of IL13 1 0.03 2.66 0.54 5.00
83 INT226517 Binding of IL19 and Il20ra 1 0.00 0.69 0.53 5.00
84 INT186713 IK Positive_regulation of Gene_expression of NOS1 1 0.00 0.55 0.49 5.00
85 INT173293 LPA Positive_regulation of OR1S1 1 0.03 0.15 0.47 5.00
86 INT173295 F2 Positive_regulation of OR1S1 1 0.01 0.15 0.46 5.00
87 INT338426 Binding of Hand1 and Hand2 2 0.06 2 0.46 5.00
88 INT186711 IK Positive_regulation of Localization of IL8 1 0.00 0.39 0.44 5.00
89 INT228732 Il13 Regulation of Gene_expression of Il5 1 0.15 0.44 0.44 5.00
90 INT226341 S1PR1 Regulation of MBTPS1 1 0.00 0.76 0.44 5.00
91 INT331799 IL8 Negative_regulation of Mapk14 1 0.01 1.6 0.42 5.00
92 INT332248 Ccl2 Positive_regulation of Ctgf 1 0.04 1.13 0.42 5.00
93 INT259637 Binding of Mmp12 and COPD 2 0.02 1.71 0.4 5.00
94 INT186758 Il13 Regulation of Ccl5 2 0.17 0.17 0.39 5.00
95 INT186757 Il13 Regulation of Ccl11 2 0.21 0.17 0.39 5.00
96 INT226381 S1PR1 Positive_regulation of Gene_expression of IK 1 0.00 0.64 0.38 5.00
97 INT193034 PRKCA Regulation of Positive_regulation of CDK20 1 0.05 0.15 0.37 5.00
98 INT226350 MBTPS1 Negative_regulation of Gene_expression of CD4 1 0.03 0.61 0.37 5.00
99 INT226374 Negative_regulation of Binding of CD4 and IFNA1 1 0.03 0.66 0.37 5.00
100 INT173356 Gnaq Positive_regulation of CDK20 1 0.06 0 0.37 5.00
101 INT170996 CCL11 Positive_regulation of SPARCL1 1 0.00 0.49 0.36 5.00
102 INT190173 BSG Regulation of MMRN1 1 0.00 0.29 0.35 5.00
103 INT299258 Dep1 Positive_regulation of Hspb8 1 0.00 2.06 0.33 5.00
104 INT180928 Binding of Col7a1 and Mmp9 1 0.03 0.96 0.32 5.00
105 INT325221 Il13 Regulation of Ccl3 1 0.08 0.17 0.32 5.00
106 INT170994 KNG1 Positive_regulation of Gene_expression of IL8 1 0.04 0.45 0.32 5.00
107 INT332255 Ptger2 Positive_regulation of Localization of Col7a1 1 0.00 0.92 0.31 5.00
108 INT325220 Il13 Negative_regulation of Ccl11 1 0.29 0.65 0.3 5.00
109 INT272925 Ccl2 Positive_regulation of Gene_expression of Col7a1 1 0.00 0.72 0.3 5.00
110 INT272932 Binding of Mmp9 and COPD 1 0.01 0.78 0.29 5.00
111 INT226512 Il1rl1 Positive_regulation of Jun 1 0.12 0.34 0.29 5.00
112 INT226375 INCENP Positive_regulation of Regulation of TH1L 1 0.01 0.57 0.29 5.00
113 INT272930 Positive_regulation of Binding of Mmp1a and COPD 1 0.01 0.79 0.29 5.00
114 INT272933 Binding of Mmp1a and COPD 1 0.01 0.78 0.29 5.00
115 INT272929 Positive_regulation of Binding of Mmp9 and COPD 1 0.01 0.79 0.29 5.00
116 INT226376 INCENP Negative_regulation of Gene_expression of TH1L 1 0.00 0.61 0.29 5.00
117 INT272928 Positive_regulation of Binding of Mmp12 and COPD 1 0.01 0.79 0.29 5.00
118 INT226505 Il1rl1 Positive_regulation of Mapk8 1 0.04 0.4 0.29 5.00
119 INT226509 Il1rl1 Positive_regulation of Gene_expression of Mapk8 1 0.05 0.4 0.29 5.00
120 INT274172 Negative_regulation of Pde4a Negative_regulation of Positive_regulation of TNF 1 0.02 0.72 0.28 5.00
121 INT226383 IL22 Positive_regulation of Gene_expression of INCENP 1 0.00 0.85 0.28 5.00
122 INT226363 IK Positive_regulation of IL22 1 0.00 0.87 0.27 5.00
123 INT332246 Ros1 Positive_regulation of Stat1 1 0.02 0.46 0.27 5.00
124 INT226343 Binding of IFNA1 and IL26 1 0.02 0.18 0.26 5.00
125 INT226352 Binding of IL22 and IL22RA1 1 0.00 0.17 0.26 5.00
126 INT226342 Binding of IL20RA and IL26 1 0.00 0.18 0.26 5.00
127 INT226355 IL9 Positive_regulation of IL22 1 0.02 0.86 0.26 5.00
128 INT226537 Hand2 Positive_regulation of IL22 1 0.02 0.86 0.26 5.00
129 INT226361 Binding of IL10 and IL22RA1 1 0.00 0.17 0.26 5.00
130 INT338424 Gtf3a Positive_regulation of Gene_expression of Ik 1 0.00 0.79 0.25 5.00
131 INT332242 Binding of Egf and Pdgfa 1 0.07 0.97 0.25 5.00
132 INT226533 Il25 Positive_regulation of Gene_expression of IL13 1 0.01 0.64 0.24 5.00
133 INT193031 CHRM2 Positive_regulation of ROCK1 1 0.00 0.12 0.24 5.00
134 INT193029 CHRM2 Positive_regulation of RHOA 1 0.01 0.12 0.24 5.00
135 INT173291 LPA Positive_regulation of LPA Positive_regulation of OR1S1 1 0.00 0.07 0.23 5.00
136 INT306795 Binding of LEP and SFTPD 1 0.08 1.13 0.23 5.00
137 INT173290 F2 Positive_regulation of LPA Positive_regulation of OR1S1 1 0.00 0.07 0.23 5.00
138 INT173294 LPA Positive_regulation of EGF 1 0.01 0.07 0.23 5.00
139 INT173358 Gnaq Positive_regulation of SMPD1 1 0.01 0.13 0.23 5.00
140 INT173292 F2 Positive_regulation of EGF 1 0.00 0.07 0.23 5.00
141 INT170993 IL10 Positive_regulation of Gene_expression of CCR1 1 0.12 0.34 0.22 5.00
142 INT173354 Gnaq Positive_regulation of CDK20 Positive_regulation of Phosphorylation of PLA2G1B 1 0.01 0 0.22 5.00
143 INT338421 Il2ra Negative_regulation of Gene_expression of Ik 1 0.00 1.27 0.22 5.00
144 INT338430 Cd4 Negative_regulation of Gene_expression of Ik 1 0.01 1.27 0.22 5.00
145 INT193033 Binding of CHRM1 and EGF 1 0.01 1.96 0.22 5.00
146 INT173353 Gnaq Positive_regulation of CDK20 Positive_regulation of Positive_regulation of PLA2G6 1 0.02 0 0.22 5.00
147 INT173357 Gnaq Positive_regulation of PRKCA 1 0.01 0 0.22 5.00
148 INT299261 Dep1 Positive_regulation of Localization of Csf2 1 0.02 0.83 0.21 5.00
149 INT299257 Dep1 Positive_regulation of Localization of Tslp 1 0.03 0.84 0.21 5.00
150 INT226511 Gene_expression of Il25 Positive_regulation of Gene_expression of Hand2 1 0.01 0.95 0.2 5.00
151 INT226373 IL19 Positive_regulation of Gene_expression of IL5 1 0.02 0.56 0.2 5.00
152 INT226336 IL19 Positive_regulation of Gene_expression of IL13 1 0.01 0.56 0.2 5.00
153 INT226379 IL19 Positive_regulation of IL5 1 0.02 0.55 0.2 5.00
154 INT226529 BTPs Negative_regulation of TH1L 1 0.05 0.22 0.2 5.00
155 INT226377 IL19 Positive_regulation of IL13 1 0.01 0.56 0.2 5.00
156 INT226514 BTPs Negative_regulation of Gene_expression of Hand2 1 0.03 0.22 0.2 5.00
157 INT226384 INCENP Positive_regulation of IL19 1 0.00 0.58 0.2 5.00
158 INT226368 Positive_regulation of TNF Positive_regulation of Positive_regulation of IGHE 1 0.11 0.92 0.2 5.00
159 INT226338 IL19 Positive_regulation of Gene_expression of IL10 1 0.01 0.56 0.2 5.00
160 INT226333 IL21 Positive_regulation of Binding of STAT4 1 0.03 0.57 0.2 5.00
161 INT226523 BTPs Negative_regulation of Gene_expression of TH1L 1 0.05 0.22 0.2 5.00
162 INT226542 Negative_regulation of Adora2b Positive_regulation of IL19 1 0.08 0.58 0.2 5.00
163 INT226510 BTPs Negative_regulation of Hand2 1 0.03 0.22 0.2 5.00
164 INT226369 IL19 Positive_regulation of IL4 1 0.03 0.55 0.2 5.00
165 INT226525 Adora2b Positive_regulation of IL19 1 0.03 0.58 0.2 5.00
166 INT226351 IL19 Positive_regulation of IL10 1 0.01 0.55 0.2 5.00
167 INT226353 IL19 Positive_regulation of Gene_expression of IL4 1 0.03 0.56 0.2 5.00
168 INT226335 Binding of IL20 and IL20RB 1 0.03 0.29 0.19 5.00
169 INT226528 BTPs Negative_regulation of Gene_expression of IL2 1 0.04 0.22 0.19 5.00
170 INT226385 Binding of IL24 and IL22RA1 1 0.00 0.28 0.19 5.00
171 INT226362 Binding of IL20 and IL22RA1 1 0.00 0.28 0.19 5.00
172 INT179683 Binding of Col7a1 and Eln 2 0.00 3.02 0.19 5.00
173 INT226370 Binding of IL24 and IL20RB 1 0.03 0.28 0.19 5.00
174 INT226345 Binding of IL24 and IL20RA 1 0.00 0.23 0.19 5.00
175 INT170995 Binding of IFNA1 and Positive_regulation of Localization of CCL5 1 0.03 0.34 0.19 5.00
176 INT226349 Binding of IL19 and IL20RA 1 0.00 0.24 0.19 5.00
177 INT226346 Binding of IL21 and Positive_regulation of Positive_regulation of JAK3 1 0.08 0.48 0.18 5.00
178 INT216841 TCIRG1 Negative_regulation of ADCY1 1 0.01 0.35 0.18 5.00
179 INT186759 Dep1 Positive_regulation of Positive_regulation of IgG 1 0.01 0.62 0.18 5.00
180 INT272931 Binding of IL8 and Cxcr1 1 0.07 0.65 0.18 5.00
181 INT226372 INCENP Negative_regulation of Gene_expression of IL5 1 0.00 1.12 0.18 5.00
182 INT193081 PRKCA Positive_regulation of Ppp1r14a 1 0.01 0.13 0.18 5.00
183 INT193080 ROCK1 Positive_regulation of Ppp1r14a 1 0.00 0.13 0.18 5.00
184 INT226344 Gene_expression of IL9 Positive_regulation of CCL5 1 0.07 1.03 0.18 5.00
185 INT216842 ATP6V0A1 Negative_regulation of ADCY1 1 0.01 0.35 0.18 5.00
186 INT226380 Gene_expression of IL15 Negative_regulation of Positive_regulation of CD8A 1 0.02 1.59 0.18 5.00
187 INT226538 Binding of IL22RA1 and Il20ra 1 0.00 0.28 0.18 5.00
188 INT226543 Binding of IL20 and Il20ra 1 0.00 0.28 0.18 5.00
189 INT226521 IL19 Positive_regulation of Gene_expression of Il6 1 0.01 0.41 0.17 5.00
190 INT226522 Nfatc3 Positive_regulation of Gene_expression of IFNA1 1 0.05 0.19 0.17 5.00
191 INT274169 Mapk1 Regulation of Pde4a 1 0.05 0.62 0.17 5.00
192 INT226536 Gene_expression of IL9 Positive_regulation of Positive_regulation of Col7a1 1 0.00 1.02 0.17 5.00
193 INT226364 IL19 Positive_regulation of Gene_expression of TNF 1 0.11 0.41 0.17 5.00
194 INT226539 Nfatc3 Positive_regulation of Gene_expression of TH1L 1 0.11 0.19 0.17 5.00
195 INT226339 Binding of IK and JAK1 1 0.00 0.46 0.16 5.00
196 INT226541 BTPs Negative_regulation of CCL11 1 0.03 0.28 0.16 5.00
197 INT226526 BTPs Negative_regulation of IL4 1 0.03 0.27 0.16 5.00
198 INT226357 Binding of IL24 and IL19 1 0.01 0.23 0.16 5.00
199 INT226503 BTPs Negative_regulation of Phosphorylation of Nfatc1 1 0.07 0.29 0.16 5.00
200 INT183697 Ducm1 Positive_regulation of Gene_expression of Cxcr2 1 0.05 0.2 0.16 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Airway Remodeling. They are ordered first by their pain relevance and then by number of times they were reported in Airway Remodeling. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT344415 Regulation of Gene_expression of Siglec5 1 0.51 2.31 0.86 100.00
2 INT344414 Positive_regulation of Gene_expression of Siglec5 1 0.57 2.82 1.26 100.00
3 INT304151 Gene_expression of Siglec5 2 0.74 17.33 6.03 99.92
4 INT72127 Protein_catabolism of MMRN1 68 0.52 56 14.13 99.92
5 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 99.92
6 INT44661 Regulation of Ahr 15 0.45 12.69 2.79 99.84
7 INT83602 Positive_regulation of Gene_expression of TRPV1 114 0.70 51.19 56.35 99.84
8 INT49805 Positive_regulation of MUC1 56 0.70 44.5 4.56 99.78
9 INT23635 Positive_regulation of MMP12 31 0.59 28.19 17.95 99.68
10 INT336621 Regulation of Fbln1 1 0.52 7.92 0.44 99.62
11 INT181280 Regulation of Gene_expression of INCENP 5 0.07 4 1.78 99.62
12 INT92877 Gene_expression of PDE5A 35 0.76 17.1 2.7 99.60
13 INT344417 Localization of Siglec5 1 0.62 0.67 0.26 99.52
14 INT58904 Localization of TH1L 40 0.68 27.11 10.52 99.52
15 INT174851 Positive_regulation of COL5A2 46 0.54 12.73 5.48 99.50
16 INT104026 Negative_regulation of Fn1 10 0.22 9.22 1.43 99.48
17 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 99.44
18 INT62041 Negative_regulation of Gene_expression of IGHE 37 0.58 37.86 5.27 99.44
19 INT338401 Transcription of Il9 1 0.23 1.63 0.22 99.44
20 INT120901 Positive_regulation of Gene_expression of Il13 36 0.57 31.63 13.36 99.38
21 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 99.38
22 INT171033 Localization of SMPD1 15 0.16 11.92 5.16 99.36
23 INT171038 Positive_regulation of Localization of SMPD1 2 0.08 1.8 0.99 99.36
24 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2 99.36
25 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73 99.28
26 INT100939 Gene_expression of Il13 176 0.73 125.1 43.38 99.20
27 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 99.20
28 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 99.18
29 INT20492 Gene_expression of MMP12 89 0.76 81.36 46.12 99.12
30 INT171013 Regulation of SMPD1 4 0.11 4.84 2.74 99.12
31 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 99.10
32 INT112017 Regulation of Hand2 77 0.36 62.23 18.04 99.08
33 INT112014 Negative_regulation of Regulation of Hand2 3 0.34 2.07 0.86 99.08
34 INT336615 Gene_expression of Fbln1 1 0.76 35.16 0.78 99.04
35 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31 99.04
36 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 99.00
37 INT156148 Gene_expression of CTGF 16 0.78 9.98 2.87 98.88
38 INT171019 Gene_expression of SMPD1 26 0.27 12.08 5.08 98.80
39 INT125312 Positive_regulation of COPD 134 0.59 162.55 20.27 98.72
40 INT190208 Positive_regulation of MMRN1 15 0.23 14.1 3.37 98.68
41 INT92678 Positive_regulation of Ecm1 30 0.09 28.41 3.68 98.60
42 INT344419 Regulation of Siglec5 1 0.43 1.57 0.41 98.58
43 INT216749 Positive_regulation of ADORA2B 6 0.37 0.89 1.72 98.52
44 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 98.48
45 INT175455 Gene_expression of Hspb8 54 0.76 59.87 3.9 98.44
46 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 98.24
47 INT70970 Binding of COPD 144 0.42 180.34 18.29 98.20
48 INT344418 Binding of Siglec5 1 0.35 0.58 0.2 98.16
49 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 98.12
50 INT46221 Positive_regulation of Gene_expression of IgG 46 0.53 33.66 7.7 98.12
51 INT16089 Gene_expression of Ltc4s 11 0.77 3.37 2.29 98.00
52 INT190204 Positive_regulation of Gene_expression of MMP12 22 0.67 31.31 13.69 98.00
53 INT171011 Localization of RETN 12 0.73 19.2 4.64 98.00
54 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54 98.00
55 INT192267 Binding of Lts1 3 0.06 1.11 0.23 97.92
56 INT160562 Localization of Cd4 49 0.71 27.58 6.78 97.60
57 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 97.56
58 INT49850 Negative_regulation of PDE4A 105 0.58 76.91 26.59 97.48
59 INT9656 Regulation of Gene_expression of Il6 57 0.62 33.3 17.71 97.32
60 INT338409 Localization of Il9 1 0.26 1.72 0.44 97.24
61 INT65260 Positive_regulation of Col7a1 95 0.69 61.73 18.42 97.12
62 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 96.96
63 INT275343 Positive_regulation of Binding of COPD 2 0.42 3.04 0.33 96.68
64 INT102848 Negative_regulation of Localization of Tgfb1 3 0.10 1.81 0.83 96.48
65 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 96.16
66 INT28671 Positive_regulation of Gene_expression of HLA-E 43 0.67 22.85 8.39 95.92
67 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61 95.92
68 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 95.44
69 INT344421 Positive_regulation of Siglec5 1 0.66 1.31 0.41 95.38
70 INT186727 Negative_regulation of Localization of PPARA 4 0.35 4.56 0.69 95.28
71 INT190203 Negative_regulation of Positive_regulation of MMP12 1 0.36 1.5 1.02 95.16
72 INT181525 Localization of Il13 24 0.66 21.51 6.55 95.12
73 INT173159 Localization of PPARA 96 0.74 64.55 10.26 94.92
74 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76 94.56
75 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 94.56
76 INT267185 Binding of Hspb8 4 0.36 6.48 0.71 94.40
77 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 94.32
78 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 94.32
79 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 94.32
80 INT244346 Positive_regulation of Rbmy1a1 1 0.03 2.84 0.18 94.32
81 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54 94.32
82 INT171032 Positive_regulation of SMPD1 9 0.12 8.94 2.52 94.24
83 INT39758 Gene_expression of Fn1 57 0.65 34.38 6.02 93.84
84 INT236953 Gene_expression of Sparcl1 2 0.14 1.73 0.83 93.84
85 INT41728 Gene_expression of CHAT 65 0.75 42.19 12.73 93.68
86 INT271411 Positive_regulation of Positive_regulation of Smad2 2 0.45 0.9 0 93.60
87 INT132997 Localization of Mmp9 59 0.80 45.9 17.61 93.52
88 INT126031 Negative_regulation of Gene_expression of MMP9 40 0.57 22.71 9.79 93.44
89 INT78895 Regulation of CCL5 30 0.46 20.45 10.18 93.32
90 INT91329 Regulation of Gene_expression of CCL4 2 0.44 1.92 1.64 93.32
91 INT129908 Positive_regulation of Smad2 5 0.45 2.13 0.3 93.20
92 INT144391 Gene_expression of RETN 42 0.75 40.48 10.47 93.12
93 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72 93.04
94 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 92.96
95 INT171035 Binding of SMPD1 1 0.06 1.57 0.17 92.72
96 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12 92.32
97 INT179654 Positive_regulation of Eln 5 0.44 4.3 0.43 92.32
98 INT88544 Gene_expression of MMRN1 102 0.75 68.8 14.55 92.00
99 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 92.00
100 INT20372 Localization of Il5 26 0.41 18.33 4.27 91.96
101 INT192268 Regulation of Gene_expression of Lts1 6 0.06 3.78 1.49 91.40
102 INT79406 Negative_regulation of Pde4a 20 0.59 25.26 8.35 91.40
103 INT26502 Negative_regulation of Gene_expression of MMP2 39 0.58 21.45 9.42 91.36
104 INT48233 Negative_regulation of Gene_expression of MMP1 34 0.58 12.94 9.08 91.36
105 INT127022 Gene_expression of Lts1 43 0.23 28.29 12.64 91.12
106 INT91337 Gene_expression of CCL4 29 0.75 16.23 8.64 90.96
107 INT60436 Negative_regulation of COPD 76 0.37 84.22 9.08 90.92
108 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72 90.80
109 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9 90.80
110 INT337540 Negative_regulation of IPCEF1 1 0.01 1.76 0.2 90.72
111 INT186269 Binding of Il13 9 0.39 7.7 1.64 90.40
112 INT132994 Positive_regulation of Localization of Mmp9 12 0.42 9.4 3.75 90.40
113 INT59387 Binding of Il9 3 0.36 0.91 0.64 90.20
114 INT112648 Positive_regulation of Fn1 19 0.49 13.73 1.66 90.16
115 INT152155 Positive_regulation of Col1a2 7 0.56 10.18 1.89 90.16
116 INT232743 Positive_regulation of LAMB2 5 0.06 1.94 0.37 90.16
117 INT171233 Binding of Ecm1 25 0.07 12.41 3.36 89.76
118 INT14947 Localization of SPARCL1 7 0.46 11.97 3.6 89.56
119 INT166707 Protein_catabolism of Col7a1 24 0.74 20.47 6.39 89.52
120 INT179670 Protein_catabolism of Eln 3 0.19 6.16 1.84 89.52
121 INT156137 Gene_expression of Col1a2 28 0.73 13.3 3.99 89.32
122 INT108931 Negative_regulation of BDNF 38 0.59 19.61 8.84 89.12
123 INT48239 Binding of Gtf3a 52 0.33 23.14 6.45 89.00
124 INT8775 Binding of IGHE 167 0.48 102.61 23.54 88.76
125 INT344416 Negative_regulation of Siglec5 1 0.55 1.31 0.39 88.72
126 INT60765 Gene_expression of LAMB2 28 0.49 13.93 2.38 88.72
127 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 88.64
128 INT173350 Localization of MRGPRX1 6 0.63 1.95 1.03 88.60
129 INT337539 Gene_expression of IPCEF1 1 0.01 1.47 0.38 88.32
130 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 88.20
131 INT216751 Gene_expression of ADORA2B 36 0.60 3.42 15.6 88.16
132 INT344422 Regulation of Localization of Ear1 1 0.07 0.41 0.05 87.76
133 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73 87.68
134 INT82854 Gene_expression of MRGPRX1 61 0.75 10.14 10.65 87.60
135 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99 87.36
136 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 87.36
137 INT134964 Regulation of Ecm1 13 0.10 7.45 2.37 87.28
138 INT97171 Localization of Ear1 7 0.43 4.25 0.44 87.12
139 INT183394 Localization of Mbp 8 0.54 3.17 0.3 87.12
140 INT344420 Localization of Ltc4s 1 0.27 0.4 0.05 87.12
141 INT96775 Gene_expression of Pdgfa 42 0.54 29.78 15.46 87.12
142 INT59449 Negative_regulation of Timp1 76 0.42 54.86 26.99 86.92
143 INT20233 Negative_regulation of SMPD1 8 0.51 4.19 1.4 86.48
144 INT94122 Negative_regulation of Mmp23 21 0.37 15.81 8.03 86.40
145 INT94466 Regulation of Gene_expression of Hand2 14 0.28 7.97 4.46 86.28
146 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 85.80
147 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47 85.76
148 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 85.76
149 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31 85.56
150 INT75833 Negative_regulation of Positive_regulation of IL8 15 0.53 6.69 5.59 85.56
151 INT274171 Negative_regulation of Binding of IL8 3 0.38 1.2 0.79 85.56
152 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 85.08
153 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06 85.08
154 INT115622 Positive_regulation of Binding of IL8 7 0.44 5.79 2.69 85.08
155 INT126984 Positive_regulation of Gene_expression of Il5 29 0.69 20.61 6.72 85.04
156 INT20380 Gene_expression of Il5 172 0.78 104.75 34.78 85.04
157 INT90202 Protein_catabolism of MMP2 15 0.94 7.47 5.41 85.04
158 INT83954 Binding of Cxcr2 21 0.37 17.27 7.65 84.76
159 INT6481 Binding of TNF 624 0.48 510.2 214.82 84.68
160 INT10834 Binding of IL8 65 0.48 41.66 16.53 84.68
161 INT103094 Binding of PPARA 308 0.47 177.26 34.75 84.52
162 INT83951 Gene_expression of Cxcr2 31 0.71 19.36 7.24 83.96
163 INT327731 Positive_regulation of Ltc4s 2 0.24 0.91 0.07 83.76
164 INT59388 Gene_expression of Il9 16 0.66 21.79 6.42 83.68
165 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41 83.44
166 INT69158 Localization of IL4 48 0.71 31.3 11.98 83.24
167 INT132822 Localization of IL13 26 0.67 22.85 6.66 83.24
168 INT171043 Negative_regulation of Gene_expression of SMPD1 2 0.08 1.15 0.53 83.20
169 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 82.80
170 INT74272 Localization of CPOX 39 0.63 25.12 10.53 82.80
171 INT6852 Localization of TNF 883 0.81 705.95 270.84 82.80
172 INT93045 Negative_regulation of Gene_expression of Hand2 31 0.43 25.26 9.24 82.80
173 INT174600 Gene_expression of Ducm1 13 0.75 4.76 0.89 82.44
174 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 82.40
175 INT39256 Localization of PTGS1 17 0.74 6.62 5.1 82.40
176 INT5332 Negative_regulation of Gene_expression of NPEPPS 11 0.04 7.79 4.29 82.16
177 INT134966 Localization of Col7a1 23 0.42 16.4 5.24 82.08
178 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 81.80
179 INT50255 Regulation of Cd4 39 0.49 29.73 6.77 81.68
180 INT5333 Gene_expression of NPEPPS 45 0.65 26.34 15.25 81.64
181 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61 81.60
182 INT16772 Gene_expression of MPO 81 0.78 90.98 11.9 81.36
183 INT228707 Positive_regulation of Gene_expression of MPO 10 0.57 17.85 2.1 81.36
184 INT24873 Binding of KLF1 12 0.07 6.73 3.1 81.32
185 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4 81.20
186 INT190189 Positive_regulation of Localization of MMP12 4 0.58 2.87 3.18 80.80
187 INT190210 Regulation of Positive_regulation of MMP12 1 0.38 1.4 1.79 80.40
188 INT171042 Negative_regulation of Protein_catabolism of MMRN1 2 0.05 1.55 0.65 80.32
189 INT234761 Binding of IL13 6 0.35 4.18 1.55 80.32
190 INT49379 Localization of MMP12 26 0.77 13.07 16.93 80.20
191 INT51685 Gene_expression of LTB4R 87 0.58 68.69 31.72 80.00
192 INT127062 Positive_regulation of Gene_expression of LTB4R 18 0.34 15.9 5.64 80.00
193 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 79.84
194 INT18909 Positive_regulation of Cd8a 92 0.60 56.55 7.35 79.72
195 INT243271 Positive_regulation of Hrh4 4 0.52 3.46 2.31 79.48
196 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 79.28
197 INT105908 Gene_expression of PDE7A 21 0.78 4.49 1.26 78.60
198 INT24672 Localization of FGF2 27 0.71 14.59 2.48 78.56
199 INT186724 Negative_regulation of Transcription of MMP9 5 0.37 1.59 1.57 78.52
200 INT99608 Transcription of MMP9 18 0.65 9.67 4.11 78.12
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