D:Alcohol Intoxication

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Disease Term
Synonyms ALCOHOLIC INTOXICATION, Drunk, DRUNKENNESS, Drunkennesses, Inebriation, INTOXICATION ALCOHOLIC
Documents 225
Hot Single Events 12
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Alcohol Intoxication. They are ordered first by their relevance to Alcohol Intoxication and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT252145 Binding of Napb and Snap25 9 0.19 0.85 0.75 88.08
2 INT185358 Binding of MCS and PCS 7 0.22 3.34 0.57 5.00
3 INT252140 Binding of Cck and Snap25 1 0.30 0.39 0.3 5.00
4 INT257397 Binding of FGD1 and INS 1 0.07 0.27 0.21 5.00
5 INT257398 Binding of FGD1 and GHRH 1 0.03 0.27 0.2 5.00
6 INT185360 Binding of PCS and Gpt 1 0.04 0.56 0.18 5.00
7 INT185359 Gpt Regulation of PCS 1 0.03 0.33 0.09 5.00
8 INT252141 Binding of Snap25 and Spata20 1 0.01 0 0.07 5.00
9 INT181168 Binding of CD79A and TAPBP 1 0.10 0.7 0.04 5.00
10 INT218240 Binding of SAE1 and Dync1h1 1 0.00 0.17 0 5.00
11 INT181169 TAPBP Negative_regulation of MALT1 1 0.00 0.48 0 5.00
12 INT181167 TAPBP Negative_regulation of CD79A 1 0.11 0.48 0 5.00
13 INT319483 Binding of LCT and HSR 1 0.11 0.23 0 5.00
14 INT252143 Bdnf Regulation of Gene_expression of Npy 1 0.11 0.49 0 5.00
15 INT181165 TAPBP Regulation of Gene_expression of CD79A 1 0.07 0.35 0 5.00
16 INT256605 FPR1 Positive_regulation of MTOR 1 0.01 2.18 0 5.00
17 INT281402 Binding of AGRP and RAPGEFL1 1 0.05 0.29 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Alcohol Intoxication. They are ordered first by their pain relevance and then by number of times they were reported in Alcohol Intoxication. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT28593 Gene_expression of Dbt 4 0.53 3.08 0.73 98.80
2 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 97.80
3 INT16622 Positive_regulation of PLXNA3 6 0.67 5.2 1.69 97.72
4 INT21156 Binding of PLXNA3 21 0.36 7.95 3.3 96.56
5 INT158083 Gene_expression of FGD1 24 0.67 6.82 2.83 93.08
6 INT184844 Gene_expression of Snap25 130 0.78 14.32 12.13 91.64
7 INT4596 Positive_regulation of SCD 18 0.42 22.59 3.26 90.92
8 INT136238 Positive_regulation of THM 3 0.25 1.03 0.04 90.88
9 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 87.32
10 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 87.00
11 INT204197 Negative_regulation of Gpr182 1 0.03 0.14 0.08 83.20
12 INT19628 Regulation of Xdh 6 0.45 1.9 1.07 81.12
13 INT141665 Gene_expression of AGRP 83 0.67 43.43 4.24 79.68
14 INT26972 Negative_regulation of Tenc1 57 0.57 56.71 16.87 74.64
15 INT20305 Gene_expression of Cyp2e1 53 0.78 19.75 19.54 73.96
16 INT65642 Binding of Dync1h1 27 0.41 15.83 2.68 72.64
17 INT157669 Regulation of CDK20 2 0.19 2.05 0.08 72.00
18 INT62760 Localization of PLXNA3 3 0.78 2.06 0.8 70.48
19 INT187971 Gene_expression of THM 6 0.36 3.56 0.32 69.28
20 INT160326 Gene_expression of Cort 8 0.59 3.35 2.11 68.88
21 INT181173 Binding of LDHD 1 0.05 0.77 0.03 68.64
22 INT205596 Negative_regulation of COQ10A 22 0.51 15.61 2.77 66.88
23 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 64.64
24 INT76924 Positive_regulation of Slc17a5 71 0.70 41.21 19.31 64.64
25 INT11203 Gene_expression of BCR 30 0.75 33.49 1.22 64.28
26 INT218763 Regulation of ZEB1 1 0.39 0.32 0.2 63.48
27 INT20307 Positive_regulation of Cyp2e1 70 0.70 23.59 32.49 61.28
28 INT33008 Gene_expression of Dync1h1 41 0.68 23.85 3.82 59.76
29 INT140394 Regulation of Dync1h1 7 0.39 2.59 1.25 59.76
30 INT91872 Gene_expression of RPA1 9 0.77 5.28 1.12 58.64
31 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 58.32
32 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 58.32
33 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6 58.32
34 INT71680 Gene_expression of CCL3 43 0.75 33.7 18.01 58.32
35 INT289202 Gene_expression of TRIO 5 0.23 1.21 1.49 56.32
36 INT4597 Regulation of SCD 5 0.39 2.25 0.5 53.36
37 INT257400 Positive_regulation of Gene_expression of FGD1 3 0.50 0.79 0.78 50.68
38 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 44.64
39 INT6406 Binding of Oprm1 280 0.48 40.54 226.26 43.44
40 INT193436 Localization of soc 5 0.65 2.17 0.15 42.56
41 INT81726 Binding of soc 42 0.42 9.92 1.61 42.52
42 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 41.28
43 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 41.04
44 INT28592 Binding of Dbt 2 0.29 0.34 0.21 39.24
45 INT45365 Negative_regulation of Cfp 68 0.57 25.44 32.11 38.00
46 INT15991 Gene_expression of FPR1 27 0.59 8.22 9.01 37.20
47 INT236972 Gene_expression of TST 8 0.58 1.02 0.04 34.48
48 INT8733 Localization of Oprm1 61 0.75 7.55 64.61 32.72
49 INT184841 Localization of Snap25 12 0.81 1.45 1.09 26.52
50 INT261017 Regulation of Gclc 2 0.22 0.88 0.06 26.36
51 INT96952 Gene_expression of Gclc 7 0.38 2.08 0.28 25.92
52 INT261026 Localization of Gclc 3 0.36 0.88 0.06 25.92
53 INT299042 Regulation of Binding of soc 1 0.53 0.31 0 23.76
54 INT11198 Negative_regulation of Gclc 3 0.59 0.49 0.87 20.16
55 INT812 Localization of INS 1026 0.81 515.6 145.31 19.04
56 INT111890 Binding of MSD 26 0.41 8.05 1.71 18.68
57 INT81725 Regulation of soc 8 0.39 2.48 0.32 17.04
58 INT218235 Negative_regulation of Gene_expression of Dync1h1 2 0.37 0.57 0.34 16.00
59 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 13.48
60 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 12.72
61 INT256619 Gene_expression of C6orf108 1 0.08 0.25 0 9.60
62 INT162064 Gene_expression of PKD2L1 12 0.63 2.71 1.1 9.28
63 INT256620 Gene_expression of RHOJ 1 0.08 0.25 0 8.92
64 INT144340 Gene_expression of Qrfpr 3 0.67 1.85 1.05 7.40
65 INT120466 Gene_expression of LCT 21 0.78 6 1.75 5.88
66 INT114189 Positive_regulation of Cort 12 0.69 4.39 4.33 5.28
67 INT443 Localization of POMC 1020 0.81 284.52 443.17 5.00
68 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29 5.00
69 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
70 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 5.00
71 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 5.00
72 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 5.00
73 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98 5.00
74 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81 5.00
75 INT2910 Regulation of Abat 169 0.62 36.95 153.53 5.00
76 INT425 Localization of PRL 455 0.81 189.64 144.8 5.00
77 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
78 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68 5.00
79 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
80 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
81 INT214 Localization of AVP 370 0.81 208.51 91.09 5.00
82 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12 5.00
83 INT14049 Positive_regulation of GRIN1 102 0.70 48.31 71.06 5.00
84 INT6849 Localization of IL1B 229 0.81 112.56 69.63 5.00
85 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
86 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 5.00
87 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
88 INT1536 Negative_regulation of NA 244 0.55 52.67 59.79 5.00
89 INT6623 Gene_expression of NA 231 0.78 45.78 59.36 5.00
90 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 5.00
91 INT74389 Gene_expression of Gdnf 131 0.78 58.52 57.06 5.00
92 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
93 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43 5.00
94 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 5.00
95 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63 5.00
96 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
97 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 5.00
98 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
99 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
100 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52 5.00
101 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 5.00
102 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
103 INT916 Regulation of Localization of PRL 92 0.62 22.98 38.13 5.00
104 INT4449 Positive_regulation of NA 179 0.55 40.26 37.82 5.00
105 INT17736 Gene_expression of Cfp 111 0.65 40.68 36.61 5.00
106 INT14031 Gene_expression of Npy 107 0.78 36.48 35.4 5.00
107 INT5743 Localization of NA 104 0.59 14.35 35.29 5.00
108 INT47710 Negative_regulation of GRIN1 71 0.57 25.57 34.24 5.00
109 INT9796 Gene_expression of Cck 63 0.78 11.44 32.09 5.00
110 INT48853 Positive_regulation of BDNF 82 0.69 43.92 27.99 5.00
111 INT5653 Positive_regulation of ELANE 136 0.70 72.78 27.94 5.00
112 INT14690 Localization of CSF2 124 0.80 85.17 27.26 5.00
113 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
114 INT6441 Positive_regulation of CRH 98 0.69 57.22 24.12 5.00
115 INT7827 Binding of Cck 32 0.48 4.66 23.73 5.00
116 INT6270 Binding of HTR1D 55 0.47 9.54 22.86 5.00
117 INT8580 Gene_expression of ELANE 132 0.75 62.98 21.79 5.00
118 INT5916 Positive_regulation of HTR1A 51 0.67 18.27 21.38 5.00
119 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
120 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
121 INT31874 Negative_regulation of Gene_expression of Abat 31 0.42 12.22 20.31 5.00
122 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9 5.00
123 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 5.00
124 INT103469 Positive_regulation of Gene_expression of BDNF 59 0.67 24.39 18.36 5.00
125 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 5.00
126 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09 5.00
127 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9 5.00
128 INT13790 Binding of HTR1A 52 0.47 18.83 17.59 5.00
129 INT6791 Binding of NA 55 0.46 5.36 17.59 5.00
130 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 5.00
131 INT213 Negative_regulation of Localization of AVP 46 0.59 19.78 16.79 5.00
132 INT57734 Binding of SLC6A4 36 0.48 11.94 15.42 5.00
133 INT71634 Gene_expression of SLC6A3 45 0.78 13.48 15.23 5.00
134 INT7776 Gene_expression of Abcb1b 63 0.75 21.35 14.92 5.00
135 INT14131 Regulation of HTR1A 34 0.60 9.61 14.74 5.00
136 INT90766 Gene_expression of PCS 93 0.77 40.48 14.51 5.00
137 INT53948 Regulation of Gene_expression of Cpox 40 0.51 20.97 13.87 5.00
138 INT18773 Localization of ALB 117 0.80 69.18 13.8 5.00
139 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 5.00
140 INT65697 Positive_regulation of GRIN3B 23 0.69 12.52 13.78 5.00
141 INT69435 Negative_regulation of ROS1 74 0.51 50.38 13.71 5.00
142 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68 5.00
143 INT26545 Gene_expression of Hras1 173 0.78 79.54 13.21 5.00
144 INT14997 Positive_regulation of FPR1 21 0.66 9.82 13.2 5.00
145 INT30961 Binding of HTR2A 33 0.47 11.44 12.86 5.00
146 INT49975 Binding of SLC6A3 34 0.47 9.86 12.41 5.00
147 INT31341 Positive_regulation of CSE 15 0.60 11.57 12.29 5.00
148 INT7682 Binding of Drd1a 22 0.48 1.8 11.83 5.00
149 INT87698 Gene_expression of WAS 25 0.58 8.75 11.83 5.00
150 INT91774 Gene_expression of Nr3c1 27 0.78 16.14 10.7 5.00
151 INT104441 Binding of NOVA2 72 0.42 16.41 10.51 5.00
152 INT1934 Positive_regulation of Cys1 68 0.68 60.56 10.47 5.00
153 INT62919 Regulation of Gnas 22 0.43 5.61 9.55 5.00
154 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 5.00
155 INT27551 Gene_expression of SERPINH1 45 0.62 42.87 9.04 5.00
156 INT108931 Negative_regulation of BDNF 38 0.59 19.61 8.84 5.00
157 INT22383 Binding of IL2 59 0.48 39.06 8.56 5.00
158 INT75907 Binding of LEP 53 0.46 46.65 8.44 5.00
159 INT88868 Binding of MCS 45 0.40 37.43 7.98 5.00
160 INT197447 Negative_regulation of Psmd1 12 0.33 4.33 7.66 5.00
161 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58 5.00
162 INT153371 Binding of Cfp 27 0.47 7.33 7.48 5.00
163 INT6652 Negative_regulation of FPR1 11 0.42 5.29 7.41 5.00
164 INT1123 Positive_regulation of CD79A 74 0.70 51.96 7.14 5.00
165 INT152030 Gene_expression of Postn 10 0.55 8.09 7.08 5.00
166 INT50990 Regulation of Cpb2 12 0.37 2.71 7.07 5.00
167 INT69441 Regulation of Gene_expression of ROS1 38 0.50 26.78 6.78 5.00
168 INT12924 Negative_regulation of Gene_expression of NA 25 0.30 6.59 6.71 5.00
169 INT53311 Positive_regulation of Gene_expression of Cfp 20 0.42 4.39 6.62 5.00
170 INT62509 Gene_expression of MCS 58 0.67 21.46 6.57 5.00
171 INT49212 Negative_regulation of GAD1 23 0.59 22.15 6.54 5.00
172 INT38807 Negative_regulation of PLA2G6 29 0.59 10.1 6.42 5.00
173 INT11258 Gene_expression of Gnas 58 0.58 21.6 6.33 5.00
174 INT57232 Binding of Casp3 22 0.36 9.42 6.2 5.00
175 INT1126 Negative_regulation of CD79A 46 0.59 31.07 6 5.00
176 INT49566 Positive_regulation of LMOD1 16 0.61 5.74 5.92 5.00
177 INT77955 Negative_regulation of PCS 55 0.43 39.32 5.76 5.00
178 INT54602 Regulation of MCS 22 0.24 10.41 5.75 5.00
179 INT134346 Binding of PCS 51 0.37 22.27 5.67 5.00
180 INT71760 Binding of CSE 9 0.48 2.84 5.42 5.00
181 INT77281 Negative_regulation of HIVEP1 132 0.49 102.78 5.36 5.00
182 INT81796 Binding of AGRP 62 0.36 37.19 5.3 5.00
183 INT10100 Binding of ELANE 22 0.47 15.32 5.19 5.00
184 INT65554 Positive_regulation of Hpse 13 0.69 8.16 5.17 5.00
185 INT19900 Binding of GHRH 22 0.37 5.75 5 5.00
186 INT32256 Gene_expression of PLXNA3 11 0.75 7.8 4.92 5.00
187 INT117204 Gene_expression of Tcm 39 0.58 10.58 4.88 5.00
188 INT479 Positive_regulation of Gfra1 25 0.69 10.71 4.76 5.00
189 INT60957 Negative_regulation of Abcb1b 18 0.57 6 4.73 5.00
190 INT51030 Negative_regulation of LMOD1 9 0.44 5.83 4.58 5.00
191 INT79902 Gene_expression of AQP1 33 0.78 24.72 4.55 5.00
192 INT36309 Negative_regulation of DIO2 18 0.57 6.42 4.51 5.00
193 INT34624 Negative_regulation of REM1 22 0.38 9.25 4.22 5.00
194 INT34184 Localization of FGD1 7 0.65 2.68 4.21 5.00
195 INT58875 Positive_regulation of FGD1 20 0.60 3.88 4.19 5.00
196 INT5148 Regulation of CD40LG 25 0.44 21.58 4.05 5.00
197 INT3405 Gene_expression of BCAR1 14 0.71 8.89 4.02 5.00
198 INT172677 Gene_expression of SHE 65 0.59 25.86 3.85 5.00
199 INT16608 Positive_regulation of FFAR1 40 0.37 18.48 3.59 5.00
200 INT19538 Positive_regulation of MPG 8 0.67 3.21 3.57 5.00
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