D:Alcoholic Liver Diseases

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Disease Term
Synonyms Alcoholic Liver Disease, Liver Disease Alcoholic
Documents 145
Hot Single Events 129
Hot Interactions 16

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Alcoholic Liver Diseases. They are ordered first by their relevance to Alcoholic Liver Diseases and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT348011 Binding of Samsn1 and Vps54 1 0.00 1.35 0.11 99.88
2 INT252801 PPP2R4 Regulation of Positive_regulation of CREB1 1 0.01 2.71 0.04 98.16
3 INT252780 Positive_regulation of CREB1 Positive_regulation of PPP2R4 1 0.01 2.71 0.04 98.16
4 INT252818 PPP2R4 Regulation of Positive_regulation of DDIT3 1 0.04 3.07 0.04 95.92
5 INT252805 ENOPH1 Positive_regulation of Gene_expression of ESR1 1 0.00 2.46 0 95.00
6 INT252792 ENOPH1 Positive_regulation of Gene_expression of DDIT3 1 0.03 2.42 0 95.00
7 INT252842 ENOPH1 Positive_regulation of Gene_expression of Ddit3 1 0.06 2.42 0 95.00
8 INT190684 Binding of A2M and IGF1 1 0.16 1.54 0.1 88.64
9 INT252821 Binding of CD4 and IL12A 1 0.02 1.36 0.19 84.76
10 INT252817 Binding of CD8A and IL12A 1 0.02 1.36 0.19 84.76
11 INT252788 Binding of IL12A and IL18 1 0.01 1.33 0.19 84.76
12 INT348032 Fndc3b Positive_regulation of Tlr2 1 0.01 1.3 0.2 82.92
13 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 81.32
14 INT343834 Binding of CD14 and IRF6 1 0.02 2.08 0.9 81.32
15 INT343859 Binding of IRF6 and TBCE 1 0.01 1.1 0.51 81.32
16 INT343860 Binding of CD14 and TBCE 1 0.03 1.1 0.51 81.32
17 INT348014 Binding of Tbk1 and Gramd3 1 0.00 1.33 0.2 78.12
18 INT190683 Binding of A2M and INS 4 0.11 4.97 0.32 77.04
19 INT348013 Negative_regulation of Binding of Irf3 and Tbk1 1 0.21 1.41 0.2 75.92
20 INT348031 Binding of Irf3 and Tbk1 1 0.17 2.82 0.4 75.52
21 INT348041 Binding of IFNA1 and Irf3 1 0.02 1.41 0.2 75.32
22 INT348027 Gramd3 Negative_regulation of Irf3 1 0.00 1.39 0.2 72.64
23 INT232893 Binding of ABR and Nup62 1 0.03 0.13 0 65.16
24 INT237907 Tlr4 Positive_regulation of Gene_expression of Tlr2 7 0.40 5.85 0.6 64.20
25 INT348040 TNF Positive_regulation of Gene_expression of Tlr2 1 0.02 0.98 0.14 64.20
26 INT348024 Binding of Chuk and Traf3 1 0.13 0.65 0.04 63.76
27 INT348028 Binding of Traf3 and Ticam1 1 0.01 0.56 0.03 60.08
28 INT252807 Binding of ACO1 and TFRC 1 0.01 1.83 0 57.52
29 INT252791 Binding of IREB2 and TFRC 1 0.02 1.82 0 57.12
30 INT343918 IgG Positive_regulation of Phosphorylation of MAPK1 1 0.01 3.57 0.91 47.16
31 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91 47.16
32 INT252784 ROS1 Positive_regulation of Gene_expression of COL1A1 1 0.05 1.86 0.24 45.44
33 INT343836 Binding of IRF6 and LBP 1 0.02 0.8 0.14 41.28
34 INT252787 Binding of FCGR3B and ROS1 1 0.06 0.58 0.2 39.76
35 INT348035 Map3k7 Positive_regulation of Binding of Chuk 1 0.20 0.06 0 36.48
36 INT348018 Map3k7 Positive_regulation of Chuk 1 0.19 0.06 0 35.84
37 INT199212 Binding of IGFBP1 and INS 1 0.05 1.77 0.04 34.04
38 INT189321 Binding of Apoa1 and Hdlcl1 1 0.00 0.68 0.2 31.12
39 INT348045 Irak2 Positive_regulation of Binding of Traf6 and Irak2 1 0.11 0.05 0 28.56
40 INT348020 Binding of Traf6 and Irak2 1 0.13 0.05 0 28.56
41 INT348037 Irak2 Positive_regulation of Binding of Traf6 1 0.18 0.05 0 28.56
42 INT348039 Binding of Myd88 and Irak2 1 0.22 0 0 21.76
43 INT334266 Binding of Irak1 and Myd88 2 0.35 0.16 0.09 20.64
44 INT334258 Binding of Myd88 and Irak4 2 0.26 0.24 0.05 20.08
45 INT232900 Binding of ABR and Krt8 1 0.03 0.49 0.03 11.52
46 INT348015 Binding of Tlr4 and Tlr3 1 0.19 0 0 11.04
47 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95 6.08
48 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95 5.00
49 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68 5.00
50 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61 5.00
51 INT288731 Binding of Got1 and Gpt 1 0.23 1.25 1.61 5.00
52 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32 5.00
53 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 5.00
54 INT343847 IRF6 Positive_regulation of TBCE 1 0.01 1.11 0.87 5.00
55 INT186672 IL8 Positive_regulation of Transcription of PTH 1 0.01 1.83 0.85 5.00
56 INT343829 TLR1 Positive_regulation of TBCE 1 0.03 0.96 0.85 5.00
57 INT331599 Tlr9 Positive_regulation of Gene_expression of Il6 1 0.03 1.8 0.73 5.00
58 INT186674 Binding of BGLAP and CYP27A1 1 0.01 1.91 0.71 5.00
59 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66 5.00
60 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63 5.00
61 INT252772 ELANE Regulation of Gene_expression of CCL2 1 0.05 2.16 0.62 5.00
62 INT252826 ROS1 Regulation of Gene_expression of CCL2 1 0.20 2.17 0.62 5.00
63 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54 5.00
64 INT253767 Binding of Hmgb1 and Tlr9 2 0.12 1.78 0.52 5.00
65 INT343838 EDA Positive_regulation of TLR4 1 0.11 0.87 0.51 5.00
66 INT343825 IRF6 Regulation of Gene_expression of FUT1 1 0.00 1.74 0.5 5.00
67 INT288729 Positive_regulation of Binding of Got1 and Gpt 1 0.25 0.61 0.49 5.00
68 INT343846 MAPK1 Positive_regulation of FOS 1 0.04 1.29 0.44 5.00
69 INT355540 Gnptg Positive_regulation of AMELX 1 0.00 2.16 0.44 5.00
70 INT343853 IRF6 Positive_regulation of PECAM1 1 0.00 0.53 0.43 5.00
71 INT186673 IL8 Positive_regulation of Positive_regulation of PTH 1 0.01 0.92 0.42 5.00
72 INT343916 Hspa1a Positive_regulation of Gene_expression of TNF 1 0.16 1.17 0.41 5.00
73 INT343919 Hspa1a Positive_regulation of Gene_expression of IL6 1 0.02 1.17 0.4 5.00
74 INT343907 Hspa1a Positive_regulation of Gene_expression of Cxcl2 1 0.01 1.17 0.4 5.00
75 INT343844 Binding of IRF6 and LY96 1 0.01 1.03 0.4 5.00
76 INT295478 IRF6 Positive_regulation of Positive_regulation of TLR4 2 0.20 0.78 0.39 5.00
77 INT329799 Binding of CD14 and LY96 2 0.04 1.02 0.39 5.00
78 INT355539 Gnptg Positive_regulation of Mmp23 1 0.00 1.18 0.35 5.00
79 INT343912 Fgg Positive_regulation of Gene_expression of IL6 1 0.00 0.83 0.35 5.00
80 INT343857 Binding of ABCC8 and LY96 1 0.02 0.96 0.34 5.00
81 INT348016 Binding of Mapk8 and Mapk8ip3 1 0.04 2.09 0.32 5.00
82 INT343856 Binding of S100A9 and ABCC8 1 0.04 0.9 0.28 5.00
83 INT252806 F2 Positive_regulation of Gene_expression of CCL2 1 0.01 0.8 0.27 5.00
84 INT343832 Positive_regulation of EDA Positive_regulation of TLR4 1 0.11 0.43 0.27 5.00
85 INT252794 Binding of IL8 and TNF 1 0.02 0.75 0.25 5.00
86 INT252795 IL8 Positive_regulation of Positive_regulation of FOS 1 0.01 0.75 0.25 5.00
87 INT252815 Binding of CCL5 and TNF 1 0.02 0.75 0.25 5.00
88 INT252822 CCL2 Positive_regulation of Positive_regulation of FOS 1 0.04 0.75 0.25 5.00
89 INT252804 TNF Regulation of Positive_regulation of FOS 1 0.01 0.76 0.25 5.00
90 INT252786 CCL2 Regulation of Positive_regulation of FOS 1 0.05 0.75 0.25 5.00
91 INT252816 IL8 Regulation of Positive_regulation of FOS 1 0.01 0.75 0.25 5.00
92 INT252793 TNF Positive_regulation of Positive_regulation of FOS 1 0.02 0.76 0.25 5.00
93 INT343864 EDA Positive_regulation of Gene_expression of TLR4 1 0.11 0.44 0.25 5.00
94 INT343914 Hmgb1 Positive_regulation of Gene_expression of IL12A 1 0.01 0.41 0.24 5.00
95 INT343906 Hmgb1 Positive_regulation of Gene_expression of Cd40 1 0.05 0.41 0.24 5.00
96 INT343911 Mthfd1 Positive_regulation of Gene_expression of IL12A 1 0.00 0.41 0.23 5.00
97 INT252777 ROS1 Positive_regulation of Gene_expression of CCL2 1 0.31 0.77 0.23 5.00
98 INT288732 Got1 Positive_regulation of Gene_expression of Gpt 1 0.31 0.52 0.23 5.00
99 INT343910 TLR4 Regulation of Gene_expression of Icam1 1 0.04 1.3 0.22 5.00
100 INT283520 Binding of DLAT and Pain1 1 0.27 0.65 0.22 5.00
101 INT331602 Binding of SSRP1 and Tlr4 1 0.03 0.9 0.21 5.00
102 INT343849 Binding of FAS and TLR4 1 0.04 0.32 0.21 5.00
103 INT252814 ELANE Positive_regulation of Positive_regulation of CCL2 1 0.05 0.8 0.2 5.00
104 INT252782 ROS1 Positive_regulation of Positive_regulation of CCL2 1 0.22 0.8 0.2 5.00
105 INT343837 TICAM1 Positive_regulation of IRF3 1 0.03 0.19 0.19 5.00
106 INT343831 TICAM1 Positive_regulation of Gene_expression of TLR4 1 0.11 0.19 0.19 5.00
107 INT343827 MIRLET7I Regulation of Gene_expression of TLR4 1 0.00 0.13 0.19 5.00
108 INT343841 ZBP1 Regulation of Transcription of IFN1@ 1 0.00 0.2 0.19 5.00
109 INT343854 TIRAP Positive_regulation of IRF3 1 0.06 0.19 0.19 5.00
110 INT291788 ALDOA Positive_regulation of Gnat3 2 0.02 0.52 0.18 5.00
111 INT343852 Binding of TRAF1 and TICAM1 1 0.03 0.19 0.17 5.00
112 INT330433 ALDOA Positive_regulation of esterase 1 0.00 0.46 0.17 5.00
113 INT343863 Binding of IRF1 and IRF3 1 0.03 0.12 0.17 5.00
114 INT343850 Binding of TRAF4 and TICAM1 1 0.03 0.19 0.17 5.00
115 INT343915 Binding of Traf1 and TICAM1 1 0.08 0.19 0.17 5.00
116 INT330430 ALDOA Positive_regulation of Pcyt2 1 0.01 0.47 0.17 5.00
117 INT348034 Mapk8ip3 Negative_regulation of Mapk8 1 0.05 0.98 0.16 5.00
118 INT331600 Il18 Regulation of IFN1@ 1 0.00 1.05 0.16 5.00
119 INT331601 Il10 Regulation of IFN1@ 1 0.00 1.05 0.16 5.00
120 INT348044 Binding of Mapk8 and Mapk8ip3 Negative_regulation of Vps54 1 0.00 1.04 0.16 5.00
121 INT348019 Negative_regulation of Binding of Mapk8 and Mapk8ip3 1 0.05 1.04 0.16 5.00
122 INT348043 Binding of Mapk8 and Mapk8ip3 Negative_regulation of Positive_regulation of Vps54 1 0.00 1.04 0.16 5.00
123 INT343848 Positive_regulation of TLR4 Positive_regulation of STAT1 1 0.17 0.16 0.15 5.00
124 INT348012 Samsn1 Positive_regulation of Vps54 1 0.00 1.93 0.15 5.00
125 INT344919 Ufm1 Regulation of Cxcr1 1 0.00 0.46 0.15 5.00
126 INT343835 TLR4 Positive_regulation of STAT1 1 0.17 0.11 0.15 5.00
127 INT259023 CADPS Positive_regulation of Binding of SH2B2 1 0.06 2.05 0.14 5.00
128 INT343828 MMRN1 Positive_regulation of TLR4 1 0.02 0.91 0.14 5.00
129 INT343833 INCENP Positive_regulation of TLR4 1 0.01 0.92 0.14 5.00
130 INT343840 Protein_catabolism of INCENP Positive_regulation of TLR4 1 0.01 0.92 0.14 5.00
131 INT343861 Binding of IFN1@ and STAT1 1 0.00 0.13 0.14 5.00
132 INT343920 Binding of TLR4 and Hmgb1 1 0.39 0.97 0.13 5.00
133 INT343917 Binding of IRF6 and Hmgb1 1 0.05 0.98 0.13 5.00
134 INT252785 ELANE Regulation of Gene_expression of FBRS 1 0.00 0.5 0.13 5.00
135 INT180345 Binding of HLA-DMA and HLA-DRB4 1 0.00 1.51 0.12 5.00
136 INT182886 Ros1 Positive_regulation of Mapk8 3 0.09 2.3 0.12 5.00
137 INT252779 Binding of ESR1 and RAF1 1 0.01 2.03 0.11 5.00
138 INT227400 Binding of DLAT and HCC 1 0.01 2.82 0.11 5.00
139 INT252778 RAF1 Positive_regulation of Positive_regulation of ROS1 1 0.04 2.05 0.11 5.00
140 INT343862 Binding of FN1 and TLR4 1 0.05 0.89 0.1 5.00
141 INT343855 Binding of MYD88 and PIK3CG 1 0.03 0.26 0.1 5.00
142 INT343858 Binding of AKT1 and MYD88 1 0.02 0.26 0.1 5.00
143 INT348042 Positive_regulation of Mapk8 Regulation of Gene_expression of VEGFA 1 0.03 0.85 0.1 5.00
144 INT343843 Binding of FN1 and IRF6 1 0.01 0.9 0.1 5.00
145 INT252790 Binding of NOS1 and NOS3 1 0.03 0.37 0.1 5.00
146 INT283460 Binding of CTLA4 and DLAT 1 0.06 3.14 0.09 5.00
147 INT343845 TICAM1 Positive_regulation of TIRAP 1 0.05 0.25 0.09 5.00
148 INT252803 Binding of NOS3 and ISYNA1 1 0.02 0.32 0.09 5.00
149 INT348025 Mapk8 Regulation of Gene_expression of Proc 1 0.00 0.58 0.08 5.00
150 INT331576 IFN1@ Positive_regulation of TNFSF10 1 0.00 0.27 0.08 5.00
151 INT331575 Negative_regulation of IFN1@ Positive_regulation of TNFSF10 1 0.00 0.27 0.08 5.00
152 INT232897 Binding of Rab27a and SAMSN1 1 0.00 0.73 0.08 5.00
153 INT343865 IRF6 Positive_regulation of TIRAP 1 0.03 0.28 0.08 5.00
154 INT348029 Re Positive_regulation of Vps54 1 0.01 0.44 0.07 5.00
155 INT348021 Stat3 Regulation of Vps54 1 0.02 1.32 0.07 5.00
156 INT232902 Binding of YWHAQ and Krt18 1 0.34 0.96 0.07 5.00
157 INT227418 Binding of DLAT and Pdc 1 0.05 1.01 0.07 5.00
158 INT232901 Regulation of Binding of YWHAQ and Krt18 1 0.41 0.96 0.07 5.00
159 INT283521 PREB Regulation of Fam89b 1 0.00 1.08 0.07 5.00
160 INT344921 Ufm1 Positive_regulation of Gene_expression of Map3k3 1 0.01 0.14 0.06 5.00
161 INT348030 Mapk8 Regulation of Re 1 0.17 0.95 0.06 5.00
162 INT180344 CYP2A6 Regulation of AMELX 1 0.01 2.01 0.05 5.00
163 INT212440 STAT3 Regulation of Phosphorylation of SOAT1 1 0.11 1.42 0.05 5.00
164 INT252823 Binding of TNF and SIGMAR1 1 0.01 0.95 0.05 5.00
165 INT180373 CYP2A6 Regulation of Cyp2d4 1 0.05 2.01 0.05 5.00
166 INT180372 CYP2A6 Regulation of Cyp1a2 1 0.03 2.02 0.05 5.00
167 INT180348 CYP2A6 Regulation of AIRE 1 0.01 2.01 0.05 5.00
168 INT330424 Binding of Aldh2 and Aldh1b1 1 0.22 0.65 0.04 5.00
169 INT212442 HGF Positive_regulation of MET 2 0.21 1.25 0.04 5.00
170 INT290727 Binding of Prdm6 and Arsi 1 0.01 0.17 0.04 5.00
171 INT252797 ROS1 Positive_regulation of Positive_regulation of FAS 1 0.08 1.03 0.04 5.00
172 INT348022 Binding of Jun and Trp53 1 0.07 0.46 0.04 5.00
173 INT283464 Binding of CD4 and DLAT 1 0.07 0.69 0.04 5.00
174 INT252768 TNF Regulation of Tnfrsf1a 1 0.01 1.02 0.04 5.00
175 INT252808 TNF Positive_regulation of NOX1 1 0.06 1.03 0.04 5.00
176 INT330425 Gene_expression of Aldh2 Negative_regulation of Zmat3 1 0.00 0.64 0.04 5.00
177 INT252767 CAT Regulation of Gpx1 1 0.00 0.25 0.04 5.00
178 INT212584 IFNA1 Regulation of Gene_expression of CD4 1 0.21 0.98 0.03 5.00
179 INT348033 Fndc3b Positive_regulation of Vps54 1 0.00 1.87 0.03 5.00
180 INT283463 Binding of DLAT and GAGE4 1 0.00 1.1 0.03 5.00
181 INT348038 Binding of Fos and Hltf 1 0.01 0.45 0.03 5.00
182 INT330426 Pcyt2 Regulation of Gene_expression of Aldh2 1 0.09 0.46 0.03 5.00
183 INT348017 Mapk8 Positive_regulation of Positive_regulation of Vps54 1 0.02 0.89 0.03 5.00
184 INT199196 Gnat3 Positive_regulation of Aldh2 2 0.26 1.06 0.03 5.00
185 INT283462 Binding of DLAT and HLA-DRB1 1 0.07 1.06 0.03 5.00
186 INT252820 ELANE Positive_regulation of Gene_expression of COL1A1 1 0.01 0.58 0 5.00
187 INT252774 ROS1 Regulation of FUT1 1 0.04 0.57 0 5.00
188 INT330432 ALDOA Positive_regulation of Binding of Aldh2 1 0.03 0.43 0 5.00
189 INT239188 Proc Positive_regulation of Akt1 3 0.01 1.72 0 5.00
190 INT343842 Binding of TRAM1 and TICAM1 1 0.01 0.12 0 5.00
191 INT252810 ROS1 Regulation of Gene_expression of MMRN1 1 0.04 0.16 0 5.00
192 INT252796 ELANE Regulation of COL1A1 1 0.01 0.57 0 5.00
193 INT232890 Binding of Rab27a and Gopc 1 0.01 0.3 0 5.00
194 INT180351 Binding of TNFRSF25 and ENAM 1 0.01 1.85 0 5.00
195 INT330428 Gnat3 Negative_regulation of Aldh2 1 0.11 0.44 0 5.00
196 INT252798 ELANE Regulation of Gene_expression of ROS1 1 0.04 0.16 0 5.00
197 INT232899 Krt18 Negative_regulation of Binding of ABR 1 0.05 0.68 0 5.00
198 INT330423 ALDOA Negative_regulation of Gnat3 Negative_regulation of Aldh2 1 0.01 0.44 0 5.00
199 INT252775 ELANE Regulation of Gene_expression of MMRN1 1 0.01 0.16 0 5.00
200 INT232895 Krt18 Positive_regulation of Gene_expression of ABR 1 0.46 0.09 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Alcoholic Liver Diseases. They are ordered first by their pain relevance and then by number of times they were reported in Alcoholic Liver Diseases. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT319472 Phosphorylation of Abcd1 1 0.02 3.12 0.31 100.00
2 INT252725 Gene_expression of ABCD1 1 0.07 3.29 0.31 100.00
3 INT72782 Positive_regulation of HCC 41 0.40 63.74 2.46 100.00
4 INT199222 Gene_expression of SAMSN1 14 0.57 18.97 1.61 100.00
5 INT170860 Localization of Samsn1 2 0.23 1.16 0.27 100.00
6 INT199226 Positive_regulation of SAMSN1 6 0.57 10.2 0.9 100.00
7 INT252756 Positive_regulation of ABCD1 2 0.05 1.78 0.24 100.00
8 INT252717 Positive_regulation of Gene_expression of SAMSN1 1 0.03 1.53 0.24 100.00
9 INT252744 Positive_regulation of Gene_expression of ABCD1 1 0.05 1.52 0.24 100.00
10 INT227411 Negative_regulation of Positive_regulation of HCC 1 0.02 1.35 0.11 100.00
11 INT22863 Negative_regulation of Apoa1 10 0.57 10.68 1.86 99.90
12 INT28042 Gene_expression of Tsc22d3 14 0.77 6.54 6.4 99.88
13 INT20336 Positive_regulation of CYP2E1 48 0.70 19.26 15.66 99.68
14 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 99.56
15 INT20305 Gene_expression of Cyp2e1 53 0.78 19.75 19.54 99.52
16 INT107087 Positive_regulation of Gene_expression of Cyp2e1 20 0.70 8.89 9.04 99.52
17 INT104980 Transcription of PRSS1 5 0.69 3.54 2.12 99.52
18 INT190692 Positive_regulation of Binding of GGT1 1 0.49 1.38 0.3 99.50
19 INT53747 Positive_regulation of Cyp2e1 34 0.70 29.03 13.39 99.40
20 INT320185 Regulation of Negative_regulation of Trap1 1 0.06 0.88 0.18 99.40
21 INT320186 Negative_regulation of Trap1 1 0.08 0.87 0.18 99.40
22 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 99.28
23 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89 99.28
24 INT155838 Binding of GGT1 7 0.47 13.27 1.11 99.20
25 INT232827 Negative_regulation of Scap 1 0.01 0.57 0 98.92
26 INT86315 Transcription of Cftr 7 0.53 4.24 2.3 98.80
27 INT190691 Negative_regulation of APOA1 12 0.42 15.9 0.39 98.76
28 INT2040 Positive_regulation of CYP2B6 95 0.69 34.3 25.6 98.68
29 INT122901 Positive_regulation of Spp1 67 0.67 58.03 7.49 98.66
30 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 98.40
31 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41 98.40
32 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33 98.18
33 INT54588 Positive_regulation of CREB1 38 0.67 12.01 9.18 98.16
34 INT20307 Positive_regulation of Cyp2e1 70 0.70 23.59 32.49 97.72
35 INT176510 Binding of Spp1 21 0.42 22.1 2 97.58
36 INT180342 Gene_expression of Asgr2 1 0.09 1.46 0.05 97.40
37 INT112506 Transcription of HGF 14 0.64 16.71 1.64 96.84
38 INT140436 Binding of TWIST1 5 0.39 2.34 0.47 96.68
39 INT138779 Positive_regulation of Localization of IRF6 25 0.45 11.51 4.51 96.56
40 INT170470 Binding of CD14 27 0.35 14.89 5.16 96.30
41 INT97798 Localization of IRF6 86 0.73 33.27 20.94 96.16
42 INT188584 Positive_regulation of Positive_regulation of TLR4 8 0.65 5.98 1.64 95.92
43 INT101105 Positive_regulation of FUT1 62 0.30 55.96 9.28 95.52
44 INT47859 Negative_regulation of Cyp2e1 41 0.59 16.92 21.72 95.32
45 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 94.80
46 INT347998 Positive_regulation of Tmem203 1 0.03 1.36 0.12 94.60
47 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 94.58
48 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 94.58
49 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 94.38
50 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 94.38
51 INT214860 Binding of GYPC 10 0.36 11.18 0.74 94.20
52 INT105923 Binding of FUT1 34 0.14 17.81 4.79 93.24
53 INT233645 Transcription of Tsc22d3 11 0.71 5.83 7.97 93.16
54 INT252833 Positive_regulation of Gene_expression of Ddit3 4 0.67 7.58 0.25 93.08
55 INT128161 Gene_expression of DDIT3 20 0.75 17.14 5.13 92.80
56 INT142483 Positive_regulation of Gene_expression of DDIT3 15 0.67 11.39 3.47 92.80
57 INT173419 Gene_expression of Ddit3 16 0.75 23.31 1.87 92.80
58 INT35584 Binding of ACLY 22 0.35 31.78 7.17 92.52
59 INT142593 Positive_regulation of Tlr2 85 0.70 75.9 13.62 92.48
60 INT152174 Negative_regulation of Samsn1 5 0.14 6.46 2.1 92.16
61 INT250645 Gene_expression of Samsn1 6 0.33 9.95 0.86 92.16
62 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6 92.00
63 INT91337 Gene_expression of CCL4 29 0.75 16.23 8.64 91.80
64 INT68758 Positive_regulation of Ros1 125 0.46 82.72 25.27 91.20
65 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03 91.12
66 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 90.68
67 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 89.92
68 INT11154 Binding of EGFR 149 0.48 96.23 6.29 89.88
69 INT112003 Localization of ROS1 94 0.73 66.32 12.16 89.80
70 INT6852 Localization of TNF 883 0.81 705.95 270.84 89.80
71 INT74423 Localization of IL10 91 0.80 61.6 22.95 89.80
72 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 89.08
73 INT4003 Positive_regulation of Gene_expression of IGHG3 31 0.46 20.38 3.16 89.08
74 INT77670 Positive_regulation of ACLY 24 0.49 21.68 3.12 89.04
75 INT147788 Regulation of FUT1 11 0.12 7.72 1.44 89.00
76 INT16130 Binding of IGF1 67 0.48 27.43 2.95 88.64
77 INT107091 Regulation of Gene_expression of Cyp2e1 4 0.62 2.17 2.03 88.56
78 INT320184 Binding of Fibp 1 0.02 1.69 0.11 88.48
79 INT202063 Regulation of Binding of TLR4 2 0.44 2.14 0.47 88.44
80 INT232841 Gene_expression of Scap 11 0.02 8.68 0.7 88.24
81 INT232838 Negative_regulation of Gene_expression of Scap 1 0.01 0.25 0 88.24
82 INT180352 Regulation of AMELX 1 0.03 4.02 0.21 87.96
83 INT180336 Regulation of Asgr2 1 0.05 1.41 0.08 87.96
84 INT10049 Negative_regulation of SERPINA1 56 0.59 44.52 9.93 87.92
85 INT233620 Positive_regulation of Gene_expression of Tsc22d3 3 0.69 1.46 1.17 87.72
86 INT28110 Transcription of MET 9 0.67 9.43 1.15 87.72
87 INT212449 Negative_regulation of Transcription of MET 1 0.29 5.31 0.06 87.72
88 INT4922 Negative_regulation of MET 19 0.57 13.97 3.7 87.32
89 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 86.96
90 INT189171 Positive_regulation of Localization of CD4 7 0.49 5.88 0.79 86.48
91 INT154772 Positive_regulation of Localization of CD8A 7 0.24 3.58 0.63 86.48
92 INT35174 Positive_regulation of Localization of IL18 7 0.69 5.22 1.08 86.48
93 INT91663 Positive_regulation of Localization of IL12A 9 0.27 5.91 1.95 86.48
94 INT31991 Gene_expression of NTS 33 0.75 12.98 4.99 86.36
95 INT17808 Regulation of NTS 14 0.44 10.7 4.02 86.36
96 INT134651 Binding of TLR4 89 0.48 66.96 23.19 86.28
97 INT33099 Negative_regulation of INSRR 32 0.40 13.82 9.85 86.20
98 INT64499 Positive_regulation of IRF6 123 0.49 52.73 27.51 85.84
99 INT17049 Localization of CD4 57 0.75 35.33 6.89 85.16
100 INT56149 Localization of CD8A 56 0.74 30.41 5.75 85.16
101 INT35175 Localization of IL18 18 0.80 12.96 3.83 85.16
102 INT91667 Localization of IL12A 39 0.74 25.51 7.36 85.16
103 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 84.56
104 INT107088 Positive_regulation of Gene_expression of Cyp7a1 1 0.03 1.7 0.26 84.52
105 INT107089 Gene_expression of Cyp7a1 2 0.44 1.05 0.45 84.52
106 INT107090 Negative_regulation of Gene_expression of Cyp7a1 1 0.03 0.85 0.13 84.52
107 INT20239 Regulation of APOA1 10 0.60 10.98 0.51 84.44
108 INT190693 Negative_regulation of Regulation of APOA1 1 0.09 1.94 0.11 84.44
109 INT78251 Positive_regulation of LBP 38 0.69 39.98 26.73 84.40
110 INT94784 Binding of ROS1 113 0.40 71.57 10.26 84.20
111 INT10886 Positive_regulation of Cyp7a1 4 0.69 1.15 0.79 84.08
112 INT123284 Positive_regulation of Positive_regulation of Cyp2e1 3 0.46 2.34 1.22 83.96
113 INT38303 Binding of Gpt 21 0.47 15.84 3.43 83.88
114 INT180332 Gene_expression of Sla 6 0.17 9.77 0.16 83.52
115 INT227337 Gene_expression of NAFLD2 7 0.05 10.98 0.83 83.52
116 INT48924 Positive_regulation of Mapk3 107 0.67 50.53 34.05 83.28
117 INT82649 Negative_regulation of Gene_expression of Cyp2e1 3 0.58 2.51 1.93 83.12
118 INT186678 Gene_expression of CALCP 2 0.65 2.32 0.14 82.96
119 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 82.84
120 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 82.56
121 INT72337 Positive_regulation of Positive_regulation of Nos2 37 0.65 17.02 8.11 82.56
122 INT92382 Positive_regulation of Gene_expression of KRAS 7 0.49 4.82 0.71 82.40
123 INT92383 Gene_expression of KRAS 38 0.65 32.94 1.32 82.40
124 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 82.28
125 INT99586 Binding of IRF6 60 0.36 27.87 13.2 81.32
126 INT257447 Binding of TBCE 4 0.08 4.68 0.66 81.32
127 INT49108 Gene_expression of TP53TG3 6 0.43 6.02 0.35 80.96
128 INT128159 Positive_regulation of DDIT3 29 0.67 29.5 8.99 80.88
129 INT2271 Gene_expression of F2 51 0.76 30.21 7.97 80.40
130 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9 80.00
131 INT189322 Binding of A2M 7 0.29 12.1 0.66 79.92
132 INT88559 Negative_regulation of Spink1 25 0.56 21.81 9.28 79.36
133 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54 79.08
134 INT9118 Gene_expression of Ceacam1 37 0.75 17.19 6.12 79.08
135 INT76159 Gene_expression of CEACAM1 5 0.65 5.12 0.24 79.08
136 INT214581 Negative_regulation of GYPC 32 0.32 21.93 3.62 78.88
137 INT180364 Gene_expression of TRNP 1 0.03 1.1 0 78.80
138 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 78.64
139 INT218577 Gene_expression of GYPC 6 0.50 5.16 0.44 77.68
140 INT314571 Binding of Tbk1 3 0.24 2.88 0.69 77.64
141 INT47839 Localization of Slc6a4 4 0.79 0.96 1.14 77.28
142 INT12240 Negative_regulation of PRSS1 46 0.57 29.5 10.77 76.88
143 INT101891 Negative_regulation of Cftr 25 0.58 24.09 9.55 76.88
144 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6 76.72
145 INT347991 Gene_expression of Tbk1 1 0.43 1.42 0.2 76.44
146 INT108997 Localization of Htt 28 0.77 3.76 1.07 76.36
147 INT447 Localization of Comt 4 0.75 0.76 1.8 76.12
148 INT347982 Negative_regulation of Tbk1 1 0.28 1.41 0.2 75.92
149 INT96915 Phosphorylation of Mapk8 73 0.81 40.69 11.44 75.88
150 INT106524 Phosphorylation of Jun 23 0.80 15.35 4.78 75.88
151 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 75.60
152 INT77947 Regulation of Gene_expression of IL12A 6 0.24 5.23 0.94 75.60
153 INT102187 Gene_expression of SH2B2 23 0.59 26.54 4.39 75.16
154 INT175260 Negative_regulation of Gene_expression of SH2B2 2 0.25 4.41 0.21 75.16
155 INT9906 Binding of CYP2E1 15 0.40 1.89 2.08 75.00
156 INT58922 Positive_regulation of OR51E1 1 0.00 0.93 0.31 75.00
157 INT144666 Positive_regulation of Binding of CYP2E1 1 0.50 0.25 0.3 75.00
158 INT9904 Gene_expression of CYP2E1 64 0.78 13.11 14.65 75.00
159 INT58923 Positive_regulation of Positive_regulation of OR51E1 1 0.00 0.46 0.15 75.00
160 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 74.72
161 INT82722 Negative_regulation of Positive_regulation of Cyp2e1 6 0.59 3.74 2.02 74.56
162 INT347992 Negative_regulation of Transcription of Irf3 1 0.28 1.41 0.2 74.48
163 INT1308 Localization of Pomc 457 0.81 66.83 217.5 74.48
164 INT79096 Binding of Cyp2e1 12 0.48 4.41 3.8 74.24
165 INT347990 Transcription of Irf3 1 0.35 1.4 0.2 73.92
166 INT28458 Localization of Slc6a3 31 0.76 2.33 12.49 73.92
167 INT101103 Positive_regulation of Positive_regulation of FUT1 5 0.27 4.25 0.85 73.92
168 INT147790 Positive_regulation of Gene_expression of FUT1 9 0.11 4.8 0.54 73.92
169 INT107307 Transcription of IFNA1 30 0.52 18.16 9.61 73.56
170 INT117031 Binding of Samsn1 6 0.21 6.82 0.76 73.04
171 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91 72.84
172 INT129398 Negative_regulation of Gene_expression of SOD1 22 0.43 7.11 1.02 72.84
173 INT83680 Gene_expression of FUT1 40 0.26 25.45 4.98 72.80
174 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 72.20
175 INT156484 Binding of Apoa1 4 0.47 6.78 1.63 72.12
176 INT699 Positive_regulation of A2M 16 0.66 10.49 2.5 72.08
177 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 72.04
178 INT347984 Negative_regulation of Irf3 1 0.28 1.38 0.2 71.96
179 INT214 Localization of AVP 370 0.81 208.51 91.09 71.68
180 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52 71.32
181 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 70.60
182 INT60571 Positive_regulation of Gsta4 8 0.45 3.76 1.44 70.48
183 INT86410 Localization of PDK1 1 0.05 0.65 0.44 70.08
184 INT186676 Negative_regulation of Transcription of PTH 1 0.11 1.31 0.16 70.08
185 INT55599 Gene_expression of GSX1 3 0.65 3.72 1.23 69.80
186 INT82214 Transcription of PTH 6 0.54 3.33 1.11 69.76
187 INT80657 Gene_expression of SLC17A5 50 0.75 39.98 5.44 69.64
188 INT95116 Negative_regulation of PDGFA 24 0.57 19.56 1.29 69.12
189 INT180361 Positive_regulation of AMELX 7 0.12 6.03 0.76 68.92
190 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 68.72
191 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05 68.60
192 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26 67.24
193 INT17686 Negative_regulation of Hdl1 72 0.36 81.85 7.74 66.40
194 INT259032 Binding of PEX1 2 0.01 4.67 0.15 66.16
195 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 65.60
196 INT9246 Positive_regulation of Cat 113 0.70 52.73 18.04 64.88
197 INT109929 Phosphorylation of MAPK8 102 0.81 39.98 16.54 64.88
198 INT252712 Phosphorylation of TRAF2 1 0.28 1.38 0 64.16
199 INT12474 Regulation of INSRR 18 0.29 6.29 4.81 63.88
200 INT252752 Phosphorylation of MTIF2 1 0.06 1.38 0 63.60
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