D:Alcoholic Pancreatitis

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Disease Term
Synonyms None
Documents 261
Hot Single Events 42
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Alcoholic Pancreatitis. They are ordered first by their relevance to Alcoholic Pancreatitis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT287794 Binding of IGHG3 and AIP 1 0.05 2.8 0.24 60.20
2 INT181490 Tryptase Positive_regulation of F2rl1 1 0.13 1.83 1.21 5.00
3 INT181491 Tryptase Positive_regulation of HTR1A 1 0.02 0.93 0.61 5.00
4 INT201512 Binding of PRSS1 and hcp 1 0.09 1.9 0.57 5.00
5 INT198307 IL10 Positive_regulation of Gene_expression of IGHG3 2 0.01 1.21 0.15 5.00
6 INT179343 Adm Positive_regulation of Pscs 1 0.33 0.51 0.1 5.00
7 INT179346 Pdgfa Positive_regulation of Positive_regulation of Mapk3 1 0.05 0.71 0.07 5.00
8 INT179345 Pdgfa Positive_regulation of Mapk3 1 0.05 0.71 0.07 5.00
9 INT179348 Pdgfa Positive_regulation of Binding of Pscs 1 0.04 0.38 0.03 5.00
10 INT179347 Pdgfa Positive_regulation of Pscs 1 0.04 0.38 0.03 5.00
11 INT179344 Pdgfa Positive_regulation of Binding of Jun 1 0.00 0.38 0.03 5.00
12 INT201490 Gene_expression of SPINK1 Negative_regulation of PRSS1 1 0.44 0.82 0.03 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Alcoholic Pancreatitis. They are ordered first by their pain relevance and then by number of times they were reported in Alcoholic Pancreatitis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT150429 Binding of Alcp1 1 0.01 0.71 0.03 100.00
2 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92 99.78
3 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41 99.78
4 INT36689 Gene_expression of Bpifa2 27 0.50 14.92 1.65 99.68
5 INT90 Localization of Gast 400 0.81 137.67 113 99.52
6 INT89 Positive_regulation of Gast 187 0.70 80.49 42.07 99.36
7 INT4075 Positive_regulation of Gene_expression of Gast 24 0.68 19.99 4.02 99.36
8 INT113604 Negative_regulation of Gene_expression of Ctgf 19 0.58 9.37 3.43 99.12
9 INT92686 Gene_expression of Ctgf 51 0.77 34.4 11.93 98.92
10 INT30 Gene_expression of Gast 158 0.78 99 41.45 98.64
11 INT12243 Positive_regulation of PRSS1 91 0.70 52.87 19.48 98.58
12 INT36554 Gene_expression of PRSS1 70 0.78 50.25 15.33 98.58
13 INT91 Positive_regulation of Localization of Gast 96 0.70 23.22 29.36 98.28
14 INT18990 Positive_regulation of GRP 32 0.70 5.22 11.23 98.16
15 INT288 Positive_regulation of Sct 88 0.70 32.83 24.5 97.64
16 INT13952 Gene_expression of Nil 11 0.65 6.4 2.93 96.72
17 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 96.72
18 INT103842 Gene_expression of Cftr 53 0.78 59.59 21.82 96.56
19 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 96.24
20 INT119753 Regulation of Pscs 7 0.45 12.88 4 96.00
21 INT94848 Negative_regulation of Gene_expression of Gpx1 11 0.30 4.91 1.7 95.40
22 INT41313 Gene_expression of Gpx1 68 0.78 34.24 11.77 95.04
23 INT12239 Regulation of Localization of CCK 11 0.62 6.03 6.61 94.12
24 INT2463 Localization of CCK 101 0.81 37.54 47.59 94.12
25 INT2885 Positive_regulation of Localization of CCK 19 0.70 9.92 8.94 94.12
26 INT85831 Positive_regulation of CA9 5 0.60 8.29 1.02 93.80
27 INT3040 Gene_expression of MIA3 81 0.24 53.61 12.62 92.80
28 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 91.68
29 INT60710 Gene_expression of Col7a1 217 0.78 113.2 35.2 91.16
30 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 91.04
31 INT20305 Gene_expression of Cyp2e1 53 0.78 19.75 19.54 89.96
32 INT79096 Binding of Cyp2e1 12 0.48 4.41 3.8 89.96
33 INT111992 Gene_expression of Pscs 40 0.76 27.47 10.74 88.92
34 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 88.80
35 INT121801 Binding of Aip 18 0.36 24.1 5.26 88.64
36 INT2818 Gene_expression of Ltf 6 0.70 2.87 1.4 85.20
37 INT24946 Binding of PRSS1 23 0.47 16.75 6.41 84.08
38 INT201496 Binding of hcp 1 0.10 4.02 1.75 83.84
39 INT63536 Gene_expression of Syncrip 7 0.67 7.23 5.44 82.80
40 INT22132 Positive_regulation of CAT 41 0.67 18.64 10.67 82.72
41 INT105114 Gene_expression of Arigg4 16 0.52 21.88 4.56 81.84
42 INT57720 Localization of IGHG3 33 0.74 20.24 6.25 81.72
43 INT287795 Localization of FAM190B 1 0.05 2.71 0.33 79.60
44 INT63365 Gene_expression of Spg21 21 0.65 12.9 7.37 77.04
45 INT1767 Positive_regulation of PROC 83 0.67 54.14 17 76.76
46 INT55597 Negative_regulation of Gpx1 59 0.55 28.3 8.83 76.20
47 INT24439 Gene_expression of Spink1 19 0.63 10.05 4.35 75.48
48 INT69769 Positive_regulation of Pscs 61 0.56 39.32 15.93 75.00
49 INT19982 Localization of Lipf 4 0.58 1.96 0.77 75.00
50 INT19981 Positive_regulation of Lipf 3 0.49 1.64 0.51 75.00
51 INT144475 Protein_catabolism of Sod2 1 0.17 0.58 0.33 75.00
52 INT144473 Protein_catabolism of Gstp1 1 0.60 0.57 0.33 75.00
53 INT144474 Protein_catabolism of Gstp1 1 0.06 0.57 0.33 75.00
54 INT24163 Positive_regulation of Prss3 8 0.59 2.9 0.65 75.00
55 INT7168 Positive_regulation of Ctsb 9 0.70 0.3 7.58 75.00
56 INT24162 Positive_regulation of Zg16 1 0.11 0.3 0.13 75.00
57 INT69952 Positive_regulation of IK 45 0.32 16.08 14.59 75.00
58 INT113987 Localization of IK 29 0.23 16.73 8.25 75.00
59 INT36945 Positive_regulation of Positive_regulation of GRP 2 0.02 0.66 0.59 75.00
60 INT19983 Positive_regulation of Localization of Lipf 2 0.50 0.7 0.24 75.00
61 INT20304 Transcription of Cyp2e1 11 0.70 2.5 2.57 74.96
62 INT148671 Gene_expression of Aip 26 0.63 24.32 3.91 73.84
63 INT16449 Binding of IGHG3 67 0.48 39.55 10.59 73.80
64 INT49802 Localization of MUC1 75 0.81 44.74 8.87 73.16
65 INT28872 Positive_regulation of CSRP1 49 0.70 47.23 11.7 71.00
66 INT109012 Binding of Bas 3 0.30 2 1.31 70.96
67 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 69.68
68 INT4015 Positive_regulation of SCTR 5 0.37 6.45 1.62 68.24
69 INT4014 Positive_regulation of Positive_regulation of SCTR 1 0.37 0.82 0.42 68.24
70 INT111958 Regulation of Thim 4 0.16 3.34 1.67 67.12
71 INT120062 Binding of AIP 4 0.42 28.86 3.91 65.00
72 INT128151 Positive_regulation of Reg3a 3 0.24 2 1.11 62.16
73 INT82743 Gene_expression of SPINK1 48 0.78 44.28 8.77 59.80
74 INT103977 Positive_regulation of Gene_expression of SPINK1 7 0.50 7.38 2.66 59.80
75 INT4047 Binding of F13A1 105 0.43 66.54 11.81 57.40
76 INT23654 Binding of SPINK1 27 0.48 30.85 11.53 56.48
77 INT23120 Regulation of Regulation of CCK 3 0.61 1.13 2.06 56.04
78 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 55.40
79 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12 55.40
80 INT159190 Gene_expression of KRT5 31 0.65 26.67 0.56 55.40
81 INT2408 Regulation of CCK 37 0.61 10.01 26.66 55.12
82 INT118131 Negative_regulation of C1s 10 0.07 2.92 1.15 55.00
83 INT55093 Negative_regulation of SPINK1 13 0.42 15.11 3.8 54.36
84 INT24122 Positive_regulation of Ltf 9 0.61 5.33 2.44 53.88
85 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 50.76
86 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 50.76
87 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 50.00
88 INT287 Localization of Cck 518 0.81 86.84 364.04 50.00
89 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 50.00
90 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 50.00
91 INT65055 Negative_regulation of Nfkb1 83 0.58 44.85 34.94 50.00
92 INT74286 Regulation of Il10 42 0.44 28.06 19.44 50.00
93 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52 50.00
94 INT10384 Positive_regulation of Nqo1 62 0.70 14.27 11.08 50.00
95 INT12240 Negative_regulation of PRSS1 46 0.57 29.5 10.77 50.00
96 INT101891 Negative_regulation of Cftr 25 0.58 24.09 9.55 50.00
97 INT5308 Regulation of Il1a 17 0.44 10.8 7.31 50.00
98 INT51137 Negative_regulation of GSTM1 39 0.43 14.74 6.5 50.00
99 INT29561 Binding of GSTM1 35 0.48 25.86 6.24 50.00
100 INT128746 Negative_regulation of Gsk3a 11 0.52 8.43 4.61 50.00
101 INT18515 Gene_expression of Lipg 18 0.66 9.3 3.72 50.00
102 INT60933 Positive_regulation of Apcs 16 0.67 11.69 3.68 50.00
103 INT69768 Negative_regulation of Pscs 7 0.51 4.76 2.82 50.00
104 INT1928 Negative_regulation of Lpl 18 0.51 11.22 2.49 50.00
105 INT48750 Binding of Nqo1 5 0.29 0.1 2.31 50.00
106 INT63081 Localization of Itpr3 13 0.67 1.08 2.12 50.00
107 INT4691 Regulation of Lipg 10 0.61 4.7 1.99 50.00
108 INT77656 Gene_expression of Hsp90aa1 12 0.78 24.27 1.81 50.00
109 INT56207 Positive_regulation of Positive_regulation of Nqo1 7 0.47 1.08 0.62 50.00
110 INT74647 Regulation of Hgf 3 0.45 3.67 0.55 50.00
111 INT48694 Regulation of Gene_expression of Lipg 2 0.21 1.5 0.51 50.00
112 INT51250 Gene_expression of Hspa4 2 0.65 1.43 0.49 50.00
113 INT88856 Negative_regulation of Gene_expression of Hsp90aa1 2 0.39 2.31 0.45 50.00
114 INT132595 Binding of Gstt1 2 0.13 1.78 0.24 50.00
115 INT230483 Protein_catabolism of Akt1 2 0.10 1.11 0.2 50.00
116 INT310369 Protein_catabolism of Trib3 2 0.01 0.43 0.2 50.00
117 INT310370 Negative_regulation of Gene_expression of Hspa4 1 0.15 0.77 0.17 50.00
118 INT310367 Gene_expression of Dnajb6 1 0.01 0.77 0.17 50.00
119 INT100573 Gene_expression of Lpl 13 0.53 2.09 0.16 50.00
120 INT79015 Negative_regulation of Gstt1 3 0.39 0.24 0.11 50.00
121 INT49266 Positive_regulation of Arigg4 37 0.47 53.79 11.2 47.68
122 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 47.44
123 INT112989 Gene_expression of AIP 3 0.56 25.4 4.23 43.36
124 INT2884 Positive_regulation of CCK 66 0.69 25.25 30.6 37.64
125 INT153115 Protein_catabolism of SPINK1 2 0.90 2.46 1.11 34.00
126 INT78659 Gene_expression of Thim 17 0.28 14.34 4.4 30.32
127 INT74444 Phosphorylation of Cp 1 0.19 1.46 0.48 25.00
128 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98 21.00
129 INT274238 Positive_regulation of AIP 2 0.42 8.14 0.97 20.40
130 INT287800 Positive_regulation of Positive_regulation of AIP 1 0.42 2.15 0.3 20.40
131 INT4003 Positive_regulation of Gene_expression of IGHG3 31 0.46 20.38 3.16 18.64
132 INT121800 Positive_regulation of Gene_expression of Arigg4 7 0.31 10.86 2.02 11.92
133 INT154449 Positive_regulation of Gene_expression of Aip 2 0.43 2.88 0.52 11.92
134 INT287798 Localization of AIP 1 0.63 5.96 1.31 10.40
135 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 5.00
136 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 5.00
137 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 5.00
138 INT292 Localization of Penk 876 0.81 88.44 669.14 5.00
139 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 5.00
140 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 5.00
141 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 5.00
142 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 5.00
143 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
144 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 5.00
145 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 5.00
146 INT798 Positive_regulation of Gene_expression of Penk 394 0.70 78.53 203.07 5.00
147 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61 5.00
148 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 5.00
149 INT1114 Localization of Ins1 748 0.80 192.95 165.48 5.00
150 INT2780 Regulation of Gene_expression of Penk 265 0.62 32.45 143.88 5.00
151 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
152 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 5.00
153 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
154 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
155 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
156 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 5.00
157 INT293 Protein_catabolism of Penk 161 1.00 11.71 98.45 5.00
158 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51 5.00
159 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 5.00
160 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98 5.00
161 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 5.00
162 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42 5.00
163 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 5.00
164 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54 5.00
165 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05 5.00
166 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 5.00
167 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 5.00
168 INT31186 Negative_regulation of Insrr 81 0.37 24.91 55.94 5.00
169 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 5.00
170 INT27954 Positive_regulation of Gene_expression of Ngf 87 0.70 57.91 51.96 5.00
171 INT2275 Negative_regulation of Localization of Ins1 183 0.59 51.02 44.94 5.00
172 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 5.00
173 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
174 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 5.00
175 INT20210 Localization of Ngf 69 0.79 46.22 38.57 5.00
176 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 5.00
177 INT48924 Positive_regulation of Mapk3 107 0.67 50.53 34.05 5.00
178 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
179 INT47764 Binding of Jun 106 0.48 22.62 31.39 5.00
180 INT59449 Negative_regulation of Timp1 76 0.42 54.86 26.99 5.00
181 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
182 INT72370 Gene_expression of Timp1 82 0.65 57.52 24.16 5.00
183 INT8775 Binding of IGHE 167 0.48 102.61 23.54 5.00
184 INT50039 Positive_regulation of Il4 48 0.55 34.8 23.34 5.00
185 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05 5.00
186 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 5.00
187 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2 5.00
188 INT47859 Negative_regulation of Cyp2e1 41 0.59 16.92 21.72 5.00
189 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
190 INT53574 Regulation of Tnf 45 0.62 40.68 19.71 5.00
191 INT18311 Positive_regulation of CD8A 145 0.69 113.48 19.44 5.00
192 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 5.00
193 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62 5.00
194 INT132997 Localization of Mmp9 59 0.80 45.9 17.61 5.00
195 INT104493 Negative_regulation of Mapk8 56 0.53 27.76 16.86 5.00
196 INT59365 Gene_expression of HTR1A 41 0.75 16.31 16.57 5.00
197 INT48238 Regulation of Gene_expression of Ngf 25 0.62 11.48 16.42 5.00
198 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89 5.00
199 INT96775 Gene_expression of Pdgfa 42 0.54 29.78 15.46 5.00
200 INT56651 Binding of HLA-DRB1 58 0.48 52.25 13.68 5.00
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