D:Allergic Rhinitis

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pChart

Disease Term
Synonyms Allergic Rhinitis Asthma, ALLERGIC RHINITIS DISORDER, Allergic Rhinitis Due To Allergen, Allergic Rhinosinusitis, Asthma Allergic Rhinitis, Copd Allergic Rhinitis Asthma, Hayfever, Non Seasonal Rhinitis, Seasonal Rhinitis
Documents 34
Hot Single Events 10
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Allergic Rhinitis. They are ordered first by their relevance to Allergic Rhinitis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT312819 IL5 Regulation of Il13 1 0.00 1.55 0.18 9.12
2 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33 5.00
3 INT356351 Binding of CALM1 and TNC 1 0.02 0 0.52 5.00
4 INT117203 Binding of IL1B and IL6 2 0.20 1.4 0.51 5.00
5 INT312708 DPP8 Positive_regulation of DPP4 1 0.24 0.54 0.19 5.00
6 INT312706 DPP9 Positive_regulation of DPP4 1 0.26 0.54 0.19 5.00
7 INT312707 Positive_regulation of DPP4 Positive_regulation of Gene_expression of CD86 1 0.20 0.45 0.13 5.00
8 INT281733 LTK Regulation of IgG 1 0.00 1.37 0.03 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Allergic Rhinitis. They are ordered first by their pain relevance and then by number of times they were reported in Allergic Rhinitis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 99.96
2 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 98.16
3 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41 94.96
4 INT103096 Regulation of PPARA 113 0.60 62.47 14.57 94.96
5 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 91.56
6 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 90.92
7 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53 90.88
8 INT86023 Transcription of PPARA 60 0.66 25.8 5.7 90.08
9 INT122584 Negative_regulation of Gene_expression of PPARA 56 0.58 37.61 9.76 89.36
10 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 82.12
11 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 79.16
12 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 79.16
13 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 79.16
14 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 73.72
15 INT181194 Regulation of Gene_expression of PPARA 31 0.44 21.27 5.96 73.72
16 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 72.60
17 INT103094 Binding of PPARA 308 0.47 177.26 34.75 72.24
18 INT2971 Regulation of IGHE 42 0.61 28.81 7.87 70.80
19 INT188714 Regulation of Negative_regulation of PPARA 2 0.32 1.44 0.61 67.60
20 INT188715 Negative_regulation of Negative_regulation of PPARA 3 0.37 1.25 0.37 67.16
21 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 66.92
22 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 65.96
23 INT132036 Negative_regulation of DPP4 126 0.59 63.24 9.51 65.84
24 INT50039 Positive_regulation of Il4 48 0.55 34.8 23.34 64.68
25 INT69303 Positive_regulation of Gene_expression of Il4 27 0.68 20.01 14.8 64.68
26 INT69160 Positive_regulation of IL5 41 0.65 36.04 7.75 64.68
27 INT69153 Positive_regulation of Gene_expression of IL5 22 0.32 23.59 5.7 64.68
28 INT21840 Positive_regulation of IL3 20 0.70 14.44 2.86 64.68
29 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42 64.28
30 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81 64.28
31 INT8803 Gene_expression of IL3 32 0.78 21.06 6.01 64.28
32 INT62041 Negative_regulation of Gene_expression of IGHE 37 0.58 37.86 5.27 57.48
33 INT95906 Negative_regulation of Positive_regulation of IGHE 6 0.55 1.56 0.36 51.44
34 INT312717 Localization of TIMM8A 1 0.02 0.82 0.1 45.28
35 INT84020 Positive_regulation of RNASE3 17 0.47 11.92 2.92 43.24
36 INT312719 Regulation of DPP9 1 0.34 0.78 0.1 40.24
37 INT312716 Regulation of DPP8 1 0.31 0.78 0.1 39.76
38 INT22030 Negative_regulation of Cysltr1 31 0.39 21.83 12.49 31.08
39 INT9996 Positive_regulation of Localization of IGHE 8 0.49 1.95 1.8 25.36
40 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 25.08
41 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 25.08
42 INT701 Localization of IGHE 87 0.80 40.5 10.62 24.72
43 INT812 Localization of INS 1026 0.81 515.6 145.31 24.68
44 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 23.92
45 INT32165 Binding of CALM1 92 0.48 24.19 29.57 23.20
46 INT75434 Gene_expression of Il13 27 0.52 26.19 15.4 17.04
47 INT71308 Gene_expression of CCL11 33 0.76 25.66 7.83 17.04
48 INT152434 Localization of CCL11 6 0.78 9.47 2.68 15.84
49 INT96234 Localization of Il13 11 0.62 10.94 5.48 13.28
50 INT69156 Localization of IL5 21 0.68 14.95 5.37 13.28
51 INT167751 Gene_expression of DSPP 15 0.77 8.56 0.24 11.84
52 INT312715 Gene_expression of DPP9 1 0.37 0.52 0.08 11.84
53 INT312721 Gene_expression of DPP7 1 0.30 0.47 0.08 11.84
54 INT312720 Gene_expression of DPP8 1 0.34 0.47 0.08 11.84
55 INT87235 Negative_regulation of Il4 54 0.48 31.51 13.15 10.56
56 INT84464 Gene_expression of DPP4 101 0.78 56.15 17.53 7.20
57 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
58 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 5.00
59 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 5.00
60 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 5.00
61 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
62 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
63 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
64 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
65 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 5.00
66 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 5.00
67 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
68 INT5008 Localization of Calca 204 0.81 80.35 125.16 5.00
69 INT1026 Binding of Lbp 207 0.48 150.96 119.16 5.00
70 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
71 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 5.00
72 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
73 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 5.00
74 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12 5.00
75 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 5.00
76 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 5.00
77 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 5.00
78 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
79 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09 5.00
80 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9 5.00
81 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 5.00
82 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 5.00
83 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17 5.00
84 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
85 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 5.00
86 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 5.00
87 INT6484 Binding of IL1B 122 0.47 75.84 35.07 5.00
88 INT1705 Gene_expression of pCA 126 0.65 88.65 34.81 5.00
89 INT660 Negative_regulation of REN 194 0.59 82.06 29.46 5.00
90 INT86437 Binding of IL6 154 0.48 121.22 29.3 5.00
91 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47 5.00
92 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59 5.00
93 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42 5.00
94 INT4877 Gene_expression of MME 184 0.78 122.82 24.78 5.00
95 INT10836 Negative_regulation of IL8 95 0.59 52.59 24.71 5.00
96 INT8775 Binding of IGHE 167 0.48 102.61 23.54 5.00
97 INT1704 Positive_regulation of PCa 68 0.59 34.92 23.36 5.00
98 INT15458 Gene_expression of NPY 50 0.76 22.67 23.03 5.00
99 INT34488 Negative_regulation of MMP2 85 0.59 41.98 21.72 5.00
100 INT78901 Localization of CCL5 67 0.78 40.79 20.59 5.00
101 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86 5.00
102 INT11243 Localization of NPY 33 0.78 11.18 19.24 5.00
103 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7 5.00
104 INT49219 Gene_expression of Hrh1 28 0.75 13.77 14.99 5.00
105 INT1758 Positive_regulation of Gene_expression of TIMP1 62 0.69 31.72 13.98 5.00
106 INT14572 Binding of INS 205 0.48 175.43 13.38 5.00
107 INT100655 Regulation of BDNF 51 0.60 21.49 13.14 5.00
108 INT26217 Binding of Calca 22 0.48 5.22 12.57 5.00
109 INT148207 Gene_expression of CTLA4 53 0.77 29.13 12.07 5.00
110 INT92574 Gene_expression of CXCL5 51 0.78 24.87 11.89 5.00
111 INT14204 Protein_catabolism of KNG1 41 0.96 20.94 11.47 5.00
112 INT80756 Gene_expression of CD86 77 0.77 46.68 11.36 5.00
113 INT78895 Regulation of CCL5 30 0.46 20.45 10.18 5.00
114 INT95632 Positive_regulation of MMP8 26 0.70 10.06 9.96 5.00
115 INT126031 Negative_regulation of Gene_expression of MMP9 40 0.57 22.71 9.79 5.00
116 INT26502 Negative_regulation of Gene_expression of MMP2 39 0.58 21.45 9.42 5.00
117 INT20664 Binding of ACE 60 0.48 35.27 9.16 5.00
118 INT108931 Negative_regulation of BDNF 38 0.59 19.61 8.84 5.00
119 INT186273 Negative_regulation of Il13 33 0.46 22.88 8.65 5.00
120 INT22481 Gene_expression of CADM1 28 0.65 30.26 8.5 5.00
121 INT139613 Binding of pr 16 0.47 5.52 8.46 5.00
122 INT36678 Binding of TIMP1 33 0.36 14.99 7.87 5.00
123 INT49488 Gene_expression of mMCP-7 37 0.75 26.11 7.68 5.00
124 INT83531 Gene_expression of KITLG 54 0.65 26 7.07 5.00
125 INT34232 Regulation of TIMP1 37 0.61 18.76 6.05 5.00
126 INT15143 Protein_catabolism of MME 16 1.00 4.56 5.54 5.00
127 INT177526 Negative_regulation of Il5 17 0.36 11.13 5.31 5.00
128 INT11062 Positive_regulation of MME 24 0.63 14.37 5.26 5.00
129 INT39000 Regulation of pr 24 0.44 12.51 4.36 5.00
130 INT133312 Binding of MMP9 25 0.42 16.79 3.83 5.00
131 INT1722 Protein_catabolism of ACE 10 0.88 2.61 3.76 5.00
132 INT13451 Positive_regulation of DPP4 23 0.68 9.33 3.62 5.00
133 INT201959 Positive_regulation of Gene_expression of DPP4 13 0.53 6.24 3.4 5.00
134 INT201952 Binding of DPP4 11 0.37 8.81 2.91 5.00
135 INT221269 Binding of BRCA1 14 0.40 31.77 2.7 5.00
136 INT4879 Positive_regulation of Gene_expression of MME 17 0.69 12.48 2.46 5.00
137 INT84465 Localization of DPP4 8 0.75 7.28 2.29 5.00
138 INT3315 Negative_regulation of Positive_regulation of INS 31 0.57 14.73 2.27 5.00
139 INT3533 Binding of REN 24 0.37 10.84 2.16 5.00
140 INT12061 Negative_regulation of LNPEP 19 0.58 5.52 2.14 5.00
141 INT84018 Gene_expression of RNASE3 15 0.65 8.27 2.12 5.00
142 INT98984 Localization of RNASE3 5 0.47 4.51 1.68 5.00
143 INT201955 Regulation of DPP4 18 0.45 11.91 1.18 5.00
144 INT151689 Positive_regulation of Gene_expression of CADM1 6 0.08 4.31 1.02 5.00
145 INT95881 Gene_expression of IGES 4 0.16 1.79 0.95 5.00
146 INT226478 Protein_catabolism of DPP4 11 0.85 5.52 0.95 5.00
147 INT298429 Gene_expression of CCL22 3 0.32 2.08 0.74 5.00
148 INT309328 Positive_regulation of Klk1b4 1 0.49 0.67 0.65 5.00
149 INT312705 Regulation of Ccl11 1 0.26 0.45 0.62 5.00
150 INT213154 Positive_regulation of Binding of TIMP1 2 0.41 1.33 0.55 5.00
151 INT267606 Protein_catabolism of CCL5 2 0.48 1.39 0.43 5.00
152 INT146792 Negative_regulation of Nf2 2 0.59 3.49 0.3 5.00
153 INT312711 Phosphorylation of DPP4 1 0.59 0.42 0.19 5.00
154 INT281732 Binding of LTK 1 0.00 1.03 0.19 5.00
155 INT312714 Positive_regulation of Phosphorylation of DPP4 1 0.44 0.42 0.19 5.00
156 INT312713 Protein_catabolism of CXCL12 1 0.37 0.45 0.17 5.00
157 INT312718 Protein_catabolism of CCL3 1 0.31 0.44 0.16 5.00
158 INT311240 Negative_regulation of Gene_expression of DPP4 6 0.59 3.43 0.13 5.00
159 INT37949 Positive_regulation of CTSC 3 0.42 1.05 0.09 5.00
160 INT281731 Positive_regulation of LTK 1 0.01 1.27 0.05 5.00
161 INT334188 Binding of Atm 1 0.10 1.18 0 5.00
162 INT334184 Positive_regulation of Regulation of pr 1 0.02 0.53 0 5.00
163 INT334185 Negative_regulation of Brip1 1 0.20 0.81 0 5.00
164 INT334186 Binding of Brip1 1 0.17 0.85 0 5.00
165 INT334189 Regulation of Binding of BRCA1 1 0.13 0.8 0 5.00
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