D:Alopecia Areata

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pChart

Disease Term
Synonyms None
Documents 43
Hot Single Events 21
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Alopecia Areata. They are ordered first by their relevance to Alopecia Areata and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79 5.00
2 INT300551 TBX21 Regulation of Hand1 2 0.10 0.44 0.48 5.00
3 INT171940 Binding of TNF and ATP2C1 1 0.08 7.32 0.39 5.00
4 INT300751 Binding of IGHE and Hand2 1 0.04 0 0.34 5.00
5 INT300727 IL25 Positive_regulation of IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
6 INT300732 IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
7 INT300728 IL33 Positive_regulation of IL4 1 0.00 0 0.33 5.00
8 INT300729 IL18 Positive_regulation of IL13 1 0.00 0 0.33 5.00
9 INT300742 Stat6 Regulation of Hand2 1 0.01 0.06 0.3 5.00
10 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3 5.00
11 INT171939 Binding of HLA-DOA and TNF 1 0.05 6.8 0.26 5.00
12 INT171938 Binding of HLA-DOA and ATP2C1 1 0.01 3.88 0.2 5.00
13 INT300753 Binding of Cd28 and Positive_regulation of Transcription of IL13 1 0.00 0 0.17 5.00
14 INT171945 PECAM1 Positive_regulation of Gene_expression of ICAM1 1 0.06 1.66 0.16 5.00
15 INT171944 ICAM1 Positive_regulation of Gene_expression of PECAM1 1 0.06 1.66 0.16 5.00
16 INT300731 IL10 Negative_regulation of Gene_expression of IGHE 1 0.03 0.23 0.13 5.00
17 INT171942 Binding of HLA-DRB1 and ATP2C1 1 0.04 2.18 0.12 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Alopecia Areata. They are ordered first by their pain relevance and then by number of times they were reported in Alopecia Areata. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT65553 Regulation of Hpse 6 0.27 3.89 1.37 100.00
2 INT65554 Positive_regulation of Hpse 13 0.69 8.16 5.17 99.62
3 INT1437 Negative_regulation of Pomc 132 0.59 35.22 60.97 99.52
4 INT114188 Negative_regulation of Cort 7 0.41 3.69 2.53 99.52
5 INT156212 Positive_regulation of Regulation of Cort 1 0.25 1.1 0.1 99.52
6 INT156213 Regulation of Cort 6 0.39 7.5 1.54 99.36
7 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 99.28
8 INT8775 Binding of IGHE 167 0.48 102.61 23.54 99.28
9 INT2971 Regulation of IGHE 42 0.61 28.81 7.87 99.28
10 INT462 Regulation of Pomc 157 0.62 41.67 67.27 99.18
11 INT163253 Binding of Flg 3 0.31 3.6 0.32 89.92
12 INT8075 Localization of Crh 64 0.81 25.41 19.45 89.48
13 INT40962 Localization of Avp 40 0.80 20.5 6.38 89.48
14 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 86.64
15 INT6474 Positive_regulation of Gene_expression of IL1RN 34 0.69 21.87 10.99 86.64
16 INT125821 Regulation of Positive_regulation of IGHE 6 0.40 5.38 0.53 86.32
17 INT171562 Regulation of IL4 19 0.36 12.12 5.33 84.32
18 INT73500 Regulation of IL13 12 0.36 10.37 3.53 84.32
19 INT73499 Positive_regulation of IL13 23 0.39 20.03 6.53 81.44
20 INT204183 Negative_regulation of Negative_regulation of CD4 3 0.30 1.79 0.22 80.52
21 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89 80.52
22 INT50340 Negative_regulation of Ifna 5 0.57 2.54 0.2 75.48
23 INT350125 Negative_regulation of Gene_expression of Ifna 1 0.41 0.49 0.1 75.48
24 INT62868 Gene_expression of Ifna 15 0.67 5.37 0.51 74.84
25 INT52625 Regulation of IL1RN 30 0.61 19.12 11.31 62.72
26 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 62.08
27 INT163114 Positive_regulation of Gene_expression of GOT1 7 0.24 8.93 0.5 62.08
28 INT4419 Gene_expression of GOT1 20 0.65 22.53 2.53 61.72
29 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09 61.40
30 INT78901 Localization of CCL5 67 0.78 40.79 20.59 61.40
31 INT78895 Regulation of CCL5 30 0.46 20.45 10.18 61.40
32 INT6852 Localization of TNF 883 0.81 705.95 270.84 58.40
33 INT73902 Regulation of Gene_expression of IL1RN 6 0.61 4.59 6.14 58.32
34 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 55.80
35 INT88322 Gene_expression of CCR5 111 0.78 77.36 39.84 49.76
36 INT97308 Gene_expression of TPO 15 0.65 13.26 2.12 40.52
37 INT8903 Gene_expression of IFNA2 58 0.71 38.23 8.68 28.08
38 INT22075 Positive_regulation of Gene_expression of IFNA2 7 0.64 4.7 1.45 28.08
39 INT91758 Binding of CCR5 28 0.45 20.16 7.07 26.64
40 INT110559 Positive_regulation of Tlr7 1 0.04 0.19 0 25.00
41 INT171953 Regulation of ATP2C1 1 0.07 2.21 0.38 11.68
42 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
43 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
44 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
45 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
46 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 5.00
47 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 5.00
48 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
49 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 5.00
50 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 5.00
51 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
52 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 5.00
53 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28 5.00
54 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 5.00
55 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 5.00
56 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22 5.00
57 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61 5.00
58 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 5.00
59 INT112017 Regulation of Hand2 77 0.36 62.23 18.04 5.00
60 INT80755 Gene_expression of CD40 88 0.75 53.68 17.86 5.00
61 INT104045 Regulation of Hand1 65 0.35 51.32 16.26 5.00
62 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 5.00
63 INT56651 Binding of HLA-DRB1 58 0.48 52.25 13.68 5.00
64 INT173505 Localization of Hand2 63 0.57 45.32 13.66 5.00
65 INT69158 Localization of IL4 48 0.71 31.3 11.98 5.00
66 INT56448 Regulation of ICAM1 52 0.60 55.1 10.96 5.00
67 INT23402 Binding of HLA-DOA 74 0.48 52.01 10.89 5.00
68 INT701 Localization of IGHE 87 0.80 40.5 10.62 5.00
69 INT15804 Gene_expression of ISG20 83 0.75 44.33 10.58 5.00
70 INT952 Negative_regulation of GHRH 57 0.56 25.3 10.34 5.00
71 INT80549 Binding of ICAM1 53 0.47 42.76 9.72 5.00
72 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 5.00
73 INT85966 Gene_expression of Cd40lg 50 0.73 30.9 9.11 5.00
74 INT89292 Positive_regulation of CCR5 27 0.70 15.12 8.59 5.00
75 INT93003 Binding of CD40 28 0.47 20.25 7.13 5.00
76 INT93046 Positive_regulation of Gene_expression of Hand2 27 0.47 24.54 7.01 5.00
77 INT132822 Localization of IL13 26 0.67 22.85 6.66 5.00
78 INT56299 Transcription of IL4 15 0.64 10.2 5.44 5.00
79 INT62041 Negative_regulation of Gene_expression of IGHE 37 0.58 37.86 5.27 5.00
80 INT6021 Binding of PRL 18 0.48 12.55 4.3 5.00
81 INT170528 Negative_regulation of Gene_expression of CD4 25 0.41 17.98 3.6 5.00
82 INT9999 Regulation of Gene_expression of IGHE 32 0.60 15.75 3.53 5.00
83 INT150395 Binding of MEFV 55 0.44 31.18 3.42 5.00
84 INT188355 Binding of Cd28 25 0.34 8.29 3.38 5.00
85 INT85971 Positive_regulation of Gene_expression of Cd40lg 14 0.66 7.61 3.29 5.00
86 INT43907 Binding of CD79A 28 0.48 28.11 3.04 5.00
87 INT98226 Negative_regulation of Cd79a 5 0.49 3.99 2.66 5.00
88 INT28815 Gene_expression of Ighd 18 0.65 11.02 2.48 5.00
89 INT221431 Negative_regulation of FOXP3 8 0.40 9.92 1.98 5.00
90 INT129240 Positive_regulation of Stat6 6 0.67 1.96 1.92 5.00
91 INT100672 Transcription of Hand2 9 0.42 2.84 1.47 5.00
92 INT5319 Positive_regulation of PTGFR 9 0.32 4.96 1.44 5.00
93 INT63339 Transcription of ICAM1 6 0.69 3.92 1.37 5.00
94 INT179169 Transcription of IL13 11 0.15 4.22 1.37 5.00
95 INT29898 Negative_regulation of C6orf25 16 0.29 9.58 1.33 5.00
96 INT9081 Positive_regulation of Positive_regulation of IGHE 5 0.42 7.13 1 5.00
97 INT102353 Positive_regulation of HLA-DQA2 6 0.06 4.07 0.82 5.00
98 INT171946 Positive_regulation of Binding of CCR5 1 0.47 3.86 0.66 5.00
99 INT152763 Binding of ATP2C1 2 0.32 4.11 0.61 5.00
100 INT103638 Negative_regulation of MEFV 7 0.39 5.88 0.54 5.00
101 INT35246 Binding of PTGFR 2 0.23 0.82 0.37 5.00
102 INT171955 Localization of ATP2C1 1 0.12 4.02 0.22 5.00
103 INT263492 Positive_regulation of Regulation of Hand2 3 0.19 4.76 0.21 5.00
104 INT284968 Positive_regulation of CDA 2 0.05 0.34 0.15 5.00
105 INT300743 Regulation of MS4A2 1 0.00 0.62 0.06 5.00
106 INT171951 Localization of CADM1 1 0.11 1.45 0.05 5.00
107 INT300746 Gene_expression of MS4A2 1 0.01 0.25 0 5.00
108 INT300748 Negative_regulation of Negative_regulation of IGHE 1 0.38 0.55 0 5.00
109 INT300749 Binding of MS4A2 1 0.00 0.38 0 5.00
110 INT285398 Positive_regulation of HLA-DRB8 1 0.01 1.11 0 5.00
111 INT300747 Positive_regulation of Negative_regulation of IGHE 1 0.41 0.63 0 5.00
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