D:Amaurosis Fugax

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pChart

Disease Term
Synonyms Blindness Monocular Transient, BLINDNESS TRANSIENT MONOCULAR, Monocular Blindness Transient, TRANSIENT MONOCULAR BLINDNESS
Documents 101
Hot Single Events 13
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Amaurosis Fugax. They are ordered first by their relevance to Amaurosis Fugax and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97 5.00
2 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62 5.00
3 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2 5.00
4 INT259023 CADPS Positive_regulation of Binding of SH2B2 1 0.06 2.05 0.14 5.00
5 INT274095 Binding of EDNRA and OPA1 1 0.12 0.65 0.04 5.00
6 INT274096 Binding of EDN1 and EDNRA Positive_regulation of Positive_regulation of EDN1 1 0.22 0.78 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Amaurosis Fugax. They are ordered first by their pain relevance and then by number of times they were reported in Amaurosis Fugax. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT259033 Gene_expression of LCA5L 1 0.01 2.71 0.16 100.00
2 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 92.52
3 INT28182 Gene_expression of Acla1 1 0.56 1.15 0.4 92.00
4 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 90.28
5 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 90.28
6 INT49258 Negative_regulation of Positive_regulation of EDN1 10 0.43 7.24 1.12 90.28
7 INT10184 Regulation of EDN1 44 0.62 23.78 10.06 89.84
8 INT49256 Regulation of Positive_regulation of EDN1 2 0.45 2.5 0.65 89.84
9 INT61791 Positive_regulation of SH2B2 9 0.50 8.36 2.99 89.68
10 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59 89.44
11 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55 83.68
12 INT19716 Gene_expression of Ecd 9 0.41 2.18 0.57 81.52
13 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 80.48
14 INT78024 Gene_expression of ACLY 73 0.75 59.15 18.54 76.32
15 INT35584 Binding of ACLY 22 0.35 31.78 7.17 74.40
16 INT28183 Positive_regulation of Acla1 1 0.66 0.88 0.23 72.08
17 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 66.16
18 INT181868 Localization of ACLY 5 0.62 6.36 1.4 59.76
19 INT322081 Positive_regulation of Abcd2 1 0.38 2.29 0.2 59.32
20 INT17182 Binding of Cea 25 0.48 14.98 4.16 56.48
21 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 50.68
22 INT76091 Positive_regulation of NOS3 48 0.61 18.4 7.92 45.52
23 INT181639 Positive_regulation of Positive_regulation of NOS3 8 0.41 3.72 1.41 45.52
24 INT14916 Binding of RASA1 15 0.37 13.64 1.44 39.84
25 INT322082 Gene_expression of Abcd2 1 0.59 3.94 0.26 39.12
26 INT102187 Gene_expression of SH2B2 23 0.59 26.54 4.39 37.20
27 INT209501 Gene_expression of CADPS 15 0.65 20.7 2.22 37.20
28 INT289423 Negative_regulation of Binding of FANCG 1 0.04 0.52 0.08 37.20
29 INT289422 Binding of FANCG 1 0.03 0.49 0.08 31.12
30 INT259039 Positive_regulation of Binding of ACLY 1 0.09 1.85 0.09 29.52
31 INT217070 Gene_expression of Acsm3 8 0.25 6.27 1.75 29.04
32 INT43900 Gene_expression of RASA1 13 0.58 12 2.03 28.08
33 INT259038 Negative_regulation of Positive_regulation of SH2B2 1 0.25 1.83 0.09 27.28
34 INT77670 Positive_regulation of ACLY 24 0.49 21.68 3.12 23.64
35 INT242921 Positive_regulation of Aoc2-ps1 1 0.12 1.82 0.04 23.52
36 INT1981 Negative_regulation of NARFL 219 0.47 223.48 16.41 13.76
37 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 6.88
38 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
39 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 5.00
40 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 5.00
41 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
42 INT79060 Gene_expression of NOS2 116 0.78 69.25 34.84 5.00
43 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19 5.00
44 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72 5.00
45 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 5.00
46 INT48766 Regulation of NOS1 73 0.61 37.01 24.59 5.00
47 INT79061 Positive_regulation of NOS2 92 0.65 58.89 23.96 5.00
48 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 5.00
49 INT9191 Localization of EDN1 94 0.81 57.01 14.78 5.00
50 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42 5.00
51 INT70905 Positive_regulation of EDNRA 49 0.67 24.33 11.79 5.00
52 INT54978 Binding of EDNRA 36 0.41 14.97 7.86 5.00
53 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51 5.00
54 INT800 Negative_regulation of Grhpr 21 0.42 10.3 7.17 5.00
55 INT32709 Negative_regulation of Hbb 30 0.54 18.27 6.97 5.00
56 INT89131 Negative_regulation of NOS2 20 0.58 9.68 6.56 5.00
57 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 5.00
58 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21 5.00
59 INT2137 Localization of Cea 27 0.70 19.22 6.14 5.00
60 INT119523 Gene_expression of EDNRB 32 0.75 26.47 5.75 5.00
61 INT70907 Negative_regulation of EDNRA 30 0.36 19.68 5.49 5.00
62 INT60776 Regulation of EDNRA 20 0.51 16.62 5.36 5.00
63 INT107386 Negative_regulation of AGTR1 37 0.55 35.94 5.15 5.00
64 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76 5.00
65 INT272273 Gene_expression of NARFL 89 0.54 121.19 4.47 5.00
66 INT124185 Negative_regulation of Kit 57 0.59 35.43 3.61 5.00
67 INT24883 Regulation of OPA1 14 0.45 9.73 3.44 5.00
68 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32 5.00
69 INT107514 Positive_regulation of Akr1b1 6 0.70 7.64 3.21 5.00
70 INT175262 Binding of SH2B2 18 0.36 22.85 3.18 5.00
71 INT5913 Binding of OPA1 12 0.41 9.33 2.92 5.00
72 INT3605 Negative_regulation of OPA1 14 0.38 10.88 2.84 5.00
73 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57 5.00
74 INT11183 Negative_regulation of SH2B2 4 0.34 6.99 2.12 5.00
75 INT49259 Regulation of Localization of EDN1 8 0.61 6.29 1.92 5.00
76 INT178130 Binding of EDNRB 12 0.36 6.18 1.84 5.00
77 INT8661 Positive_regulation of Positive_regulation of EDN1 10 0.66 10.9 1.76 5.00
78 INT139514 Localization of EDNRB 7 0.73 4.63 1.52 5.00
79 INT93350 Binding of Lepr 17 0.05 27.21 1.5 5.00
80 INT12035 Regulation of F2 21 0.45 12.66 1.47 5.00
81 INT259036 Transcription of SH2B2 2 0.55 7.01 1.46 5.00
82 INT199550 Negative_regulation of Flt1 18 0.37 12.57 1.37 5.00
83 INT236277 Positive_regulation of Gene_expression of CADPS 5 0.42 9.17 1.29 5.00
84 INT144019 Negative_regulation of Pdgfrb 21 0.58 14.93 1.26 5.00
85 INT272274 Localization of NARFL 24 0.60 27.55 1.18 5.00
86 INT209503 Positive_regulation of CADPS 3 0.42 7 1.11 5.00
87 INT228770 Gene_expression of amd 16 0.57 21.49 1.05 5.00
88 INT205912 Negative_regulation of Gene_expression of Jak2 8 0.42 5.1 1.04 5.00
89 INT99966 Negative_regulation of Positive_regulation of NARFL 13 0.37 13.32 0.98 5.00
90 INT89288 Positive_regulation of Negative_regulation of NOS1 5 0.40 4.84 0.96 5.00
91 INT115069 Positive_regulation of Localization of Cea 5 0.34 3.31 0.95 5.00
92 INT139515 Positive_regulation of EDNRB 15 0.67 10.35 0.93 5.00
93 INT199563 Negative_regulation of Abl1 38 0.46 21.5 0.87 5.00
94 INT272275 Regulation of Positive_regulation of NARFL 8 0.36 16.68 0.86 5.00
95 INT122811 Binding of Ecd 11 0.31 3.01 0.84 5.00
96 INT178127 Positive_regulation of Gene_expression of EDNRB 7 0.51 5.24 0.78 5.00
97 INT52740 Binding of ACLS 5 0.31 3 0.54 5.00
98 INT293957 Localization of PION 1 0.55 2 0.53 5.00
99 INT259035 Localization of SH2B2 3 0.43 1.77 0.42 5.00
100 INT259031 Negative_regulation of Gene_expression of CADPS 1 0.07 3.04 0.35 5.00
101 INT139512 Positive_regulation of Localization of EDNRB 3 0.37 0.69 0.26 5.00
102 INT17009 Regulation of CADPS 2 0.08 1.97 0.24 5.00
103 INT322080 Regulation of Binding of Ecd 1 0.03 1.38 0.21 5.00
104 INT175260 Negative_regulation of Gene_expression of SH2B2 2 0.25 4.41 0.21 5.00
105 INT274098 Regulation of EDNRB 1 0.33 2.41 0.18 5.00
106 INT157725 Gene_expression of ACLS 2 0.13 2.89 0.17 5.00
107 INT259032 Binding of PEX1 2 0.01 4.67 0.15 5.00
108 INT259037 Negative_regulation of Binding of ACLY 1 0.07 1.54 0.13 5.00
109 INT242922 Positive_regulation of Gene_expression of amd 2 0.43 5.99 0.1 5.00
110 INT200792 Regulation of Gene_expression of Jak2 5 0.61 5.69 0.09 5.00
111 INT322083 Binding of Abcd2 1 0.29 0.92 0.08 5.00
112 INT259030 Negative_regulation of Gene_expression of ACLY 1 0.07 1.95 0.08 5.00
113 INT293958 Gene_expression of PION 1 0.49 1.69 0.06 5.00
114 INT259040 Phosphorylation of SH2B2 1 0.47 0.85 0.03 5.00
115 INT259029 Regulation of Phosphorylation of SH2B2 1 0.26 0.85 0.03 5.00
116 INT259024 Regulation of Anxa5 1 0.44 1.25 0 5.00
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