D:Amyloid Plaque

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pChart

Disease Term
Synonyms Amyloid Deposit, Amyloid Deposits, Amyloid Plaques, Deposit Amyloid, Deposits Amyloid, NEURITIC PLAQUE, Neuritic Plaques, Plaque Neuritic, Plaque Senile, PLAQUES AMYLOID, Plaques Neuritic
Documents 500
Hot Single Events 200
Hot Interactions 48

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Amyloid Plaque. They are ordered first by their relevance to Amyloid Plaque and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT236009 HIST2H2AA3 Positive_regulation of Protein_catabolism of APP 1 0.02 0.19 0.04 100.00
2 INT137834 Binding of CAMK2B and CTS 1 0.05 1.38 0.42 99.96
3 INT210549 Binding of BCHE and Ache 1 0.01 0.82 0.12 99.76
4 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 98.74
5 INT236016 ROS1 Positive_regulation of MAPK8 2 0.18 1.81 0 97.96
6 INT167619 Protein_catabolism of Ppp2cb Positive_regulation of App 1 0.00 0.88 0.44 97.44
7 INT242163 Wnt2 Positive_regulation of Regulation of Apc 1 0.13 0.71 0.13 96.28
8 INT236014 HIST2H2AA3 Positive_regulation of MAPK8 1 0.02 0.44 0 95.12
9 INT327366 Binding of Fap and Ttr 1 0.33 2.9 0.28 95.08
10 INT167617 Bace2 Positive_regulation of App 1 0.06 0.87 0.44 94.60
11 INT179566 Binding of C1qa and Ywhaq 1 0.00 0.56 0.26 94.52
12 INT270416 PLAT Negative_regulation of Positive_regulation of PLG 1 0.00 0.48 0.15 94.32
13 INT106073 IL1B Positive_regulation of Positive_regulation of NFKB1 1 0.41 0.7 0.47 94.16
14 INT182096 Positive_regulation of Binding of Il6 and Il1 2 0.09 4.26 1.31 93.72
15 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57 93.72
16 INT187795 Positive_regulation of Binding of Tnf and Il1 1 0.13 1.87 0.48 93.72
17 INT167621 Psenen Positive_regulation of App 1 0.02 0.86 0.44 93.68
18 INT262708 Bace1 Positive_regulation of Gene_expression of App 1 0.44 2.82 0 93.64
19 INT288099 Binding of APP and App 1 0.01 1.04 0.05 93.32
20 INT237415 Il1rn Regulation of Il10 1 0.03 0.96 0.39 93.04
21 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46 92.52
22 INT237417 Il1rn Regulation of Il4 1 0.02 0.96 0.39 92.48
23 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55 92.40
24 INT187796 Binding of Tnf and Il1 1 0.09 1.85 0.48 92.40
25 INT220623 Binding of Stat1 and Bace1 11 0.25 10.33 3.81 91.36
26 INT328228 Binding of Cpox and Hmox1 1 0.03 0.83 0.23 91.32
27 INT266381 Positive_regulation of Ager Positive_regulation of Nfkb1 1 0.00 0.77 0.55 90.64
28 INT158922 Positive_regulation of Binding of TSPO and Tspo 1 0.54 0.83 0.28 88.84
29 INT250151 Binding of GSS and MCM3 1 0.01 1.38 0.04 87.84
30 INT108808 Binding of IAPP and INS 1 0.32 1.36 0.23 87.44
31 INT158923 Binding of TSPO and Tspo 1 0.40 0.82 0.28 87.36
32 INT236015 HIST2H2AA3 Positive_regulation of Gene_expression of APP 1 0.02 0.95 0.04 87.32
33 INT188702 St6galnac2 Positive_regulation of Gene_expression of Stab1 1 0.00 5.09 1.23 87.28
34 INT188695 St6galnac2 Positive_regulation of Stab1 1 0.00 2.53 0.61 86.96
35 INT188693 Regulation of St6galnac2 Positive_regulation of Stab1 1 0.00 2.64 0.61 86.96
36 INT188705 St6galnac2 Positive_regulation of Localization of Stab1 1 0.00 1.27 0.31 86.96
37 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48 86.24
38 INT201758 BDNF Regulation of Positive_regulation of Ltp 1 0.04 1.17 0.19 86.08
39 INT201764 BDNF Regulation of Positive_regulation of Bdnf 1 0.10 1.15 0.19 86.08
40 INT242847 Binding of CDB2 and TGFBI 1 0.17 0.56 0 83.64
41 INT217398 Binding of Psen2 and Bace1 1 0.12 1.44 0 80.44
42 INT217400 Binding of Psen1 and Bace1 1 0.17 1.43 0 80.44
43 INT238802 Binding of Ager and Renbp 6 0.02 6.46 0.22 80.44
44 INT217402 Binding of Bace1 and PSENEN 1 0.02 0.72 0 80.44
45 INT217399 Binding of Bace1 and Ncstn 1 0.05 0.72 0 80.44
46 INT217397 Binding of Bace1 and Alph1 1 0.02 0.73 0 80.44
47 INT167618 Rho Regulation of App 1 0.17 0.88 0.55 80.32
48 INT237414 Binding of Jak2 and Bace1 1 0.20 0.77 0.39 80.24
49 INT308660 Binding of Ager and App 1 0.08 1.22 0.12 79.60
50 INT55809 Binding of Ttr and Fap 1 0.12 2.56 0.19 79.52
51 INT188707 Binding of IFNA1 and Hand1 1 0.01 0.56 0.32 79.52
52 INT167620 Rock2 Regulation of App 1 0.13 0.87 0.55 79.44
53 INT270433 PLAT Positive_regulation of Positive_regulation of Gsk3b 1 0.04 0.5 0.21 78.76
54 INT201755 ROS1 Positive_regulation of Casp3 1 0.00 1.4 0 78.44
55 INT242164 Wnt2 Positive_regulation of Localization of Apc 1 0.13 1.53 0.32 76.32
56 INT308659 Binding of Ager and ecs 1 0.01 1.14 0.12 76.04
57 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35 75.76
58 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16 74.48
59 INT323967 Il6 Positive_regulation of Gene_expression of App 1 0.10 0.86 0.38 74.48
60 INT321683 Binding of Aicda and Mapt 1 0.36 1.23 0.04 73.12
61 INT275754 Regulation of Binding of xn and Igfbp3 1 0.02 0.79 0.04 73.04
62 INT275758 Binding of xn and Igfbp3 1 0.03 5.39 0.04 72.60
63 INT142955 Positive_regulation of Binding of APP and BACE1 1 0.48 0.5 0 70.76
64 INT142954 Binding of APP and BACE1 1 0.37 0.5 0 70.36
65 INT145260 Binding of CLU and App 1 0.00 0.74 0.46 69.72
66 INT308647 Ager Positive_regulation of Gene_expression of Bace1 1 0.09 1.01 0.12 69.16
67 INT250150 Binding of IKBKG and SACM1L 1 0.00 2.78 0.06 68.96
68 INT268176 Positive_regulation of Erc1 Positive_regulation of Gene_expression of Prnp 1 0.06 0.2 0 68.88
69 INT106074 IL1B Positive_regulation of Gene_expression of A2M 1 0.03 0.75 0.49 67.12
70 INT106072 NFKB1 Positive_regulation of Gene_expression of A2M 1 0.19 0.75 0.49 67.12
71 INT250153 Binding of PRNP and IKBKG 1 0.09 2.83 0.06 66.32
72 INT267156 Binding of VDR and SUGT1 1 0.04 3.4 0.09 64.64
73 INT236017 GOPC Positive_regulation of MAPK8 1 0.09 0.17 0 63.52
74 INT188195 GOPC Positive_regulation of MAPK1 2 0.21 0.32 0.22 63.32
75 INT236011 HIST2H2AA3 Positive_regulation of MAPK1 1 0.00 0.17 0 63.32
76 INT261579 Serpinc1 Negative_regulation of Gene_expression of CYBB 1 0.00 1.69 0.18 63.20
77 INT236010 GOPC Positive_regulation of AKT1 1 0.03 0.17 0 63.00
78 INT236012 HIST2H2AA3 Positive_regulation of AKT1 1 0.00 0.17 0 63.00
79 INT268188 Binding of Prnp and Erc1 1 0.04 0.27 0 61.16
80 INT282708 Binding of MAPT and Y301C7L 1 0.00 0.54 0.16 59.84
81 INT298996 Il18 Positive_regulation of Gene_expression of Cdk5r1 1 0.03 1.65 0.29 59.48
82 INT298995 Il18 Positive_regulation of Gene_expression of Cdk5 1 0.12 1.65 0.29 59.48
83 INT299008 Il18 Positive_regulation of Transcription of Cdk5 1 0.12 1.65 0.29 59.48
84 INT299011 Il18 Positive_regulation of Transcription of Cdk5r1 1 0.03 1.65 0.29 59.48
85 INT261648 BDKRB1 Regulation of PRKCA 1 0.03 1.9 0.47 59.24
86 INT175196 Binding of NCOR1 and NUP62 1 0.02 0.84 0.12 58.00
87 INT316054 Eif1 Positive_regulation of Il6 1 0.00 0.78 0.21 57.76
88 INT316062 Ps Positive_regulation of Il6 1 0.04 0.77 0.21 57.76
89 INT268186 Positive_regulation of Binding of Gpi1 and Erc1 1 0.01 0.17 0 57.72
90 INT268189 Binding of Gpi1 and Erc1 1 0.01 0.17 0 57.16
91 INT316063 Ps Positive_regulation of IL8 1 0.09 1.33 0.41 56.76
92 INT316065 Eif1 Positive_regulation of IL8 1 0.01 1.34 0.41 56.76
93 INT217396 Binding of Abca1 and App 1 0.26 0.83 0 56.36
94 INT195122 Il1 Positive_regulation of Gene_expression of Gtf3a 1 0.02 1.38 0.5 55.48
95 INT107917 RETNLB Positive_regulation of Gene_expression of App 1 0.01 1.2 0.79 55.28
96 INT333544 CTSB Regulation of Protein_catabolism of APP 1 0.01 0.53 0.62 53.84
97 INT333543 CTSB Regulation of APP 1 0.01 0.53 0.62 53.84
98 INT268446 Cdk5 Positive_regulation of Cdk5r1 1 0.02 0.58 0 51.36
99 INT162754 Negative_regulation of Binding of APP and Slc30a2 1 0.00 1.26 0.04 49.48
100 INT120205 Binding of App and Ern1 1 0.05 2.55 1.18 49.24
101 INT120203 Binding of App and Il1 1 0.17 1.28 0.59 49.24
102 INT120204 Binding of App and Il1f5 1 0.09 1.28 0.59 49.24
103 INT120206 Binding of UTS2R and Il1 1 0.17 1.28 0.59 49.24
104 INT120207 Binding of UTS2R and Il1f5 1 0.09 1.28 0.59 49.24
105 INT162753 Binding of APP and Slc30a2 1 0.00 1.25 0.04 49.00
106 INT268187 Rab4a Regulation of Rab22a 1 0.15 0.12 0 48.84
107 INT308652 Binding of Renbp and Nps 1 0.01 1.38 0.09 47.52
108 INT237907 Tlr4 Positive_regulation of Gene_expression of Tlr2 7 0.40 5.85 0.6 46.56
109 INT242162 Binding of Ccnd1 and Wnt2 1 0.10 0.23 0.34 45.48
110 INT266393 Binding of Ager and Fn1 1 0.00 0.82 0.39 43.40
111 INT266397 Binding of Ager and Col4a1 1 0.00 0.81 0.38 43.40
112 INT266382 Binding of Col4a1 and Fn1 1 0.00 0.82 0.39 43.20
113 INT308643 Binding of Proc and Renbp 1 0.00 1.61 0 40.96
114 INT201748 Car2 Positive_regulation of Cdk5r1 1 0.00 0.67 0.09 35.60
115 INT201751 Car2 Positive_regulation of Cdk5 1 0.00 0.67 0.09 35.60
116 INT236363 Regulation of Binding of Ptprc and Tlr4 1 0.25 1.23 0.06 34.24
117 INT275752 xn Positive_regulation of Phosphorylation of Stat3 1 0.04 0.58 0 33.68
118 INT340743 Negative_regulation of CSF2 Positive_regulation of ZNF807 1 0.00 1.77 0 33.32
119 INT340745 CSF2 Positive_regulation of ZNF807 1 0.00 1.76 0 33.32
120 INT198920 Binding of Ldlr and Lrpap1 1 0.05 0.06 0 33.24
121 INT231507 Binding of Ptprc and Tlr4 2 0.21 1.22 0.06 32.16
122 INT231244 Binding of Fus and Alms1 1 0.20 0.57 0.17 30.60
123 INT204488 Binding of Fmr1 and Ncl 1 0.12 0.61 0 28.16
124 INT139980 Negative_regulation of CTSB Negative_regulation of Gene_expression of APP 1 0.15 0.7 0.26 25.00
125 INT139981 CTSB Negative_regulation of Gene_expression of APP 1 0.11 0.7 0.26 25.00
126 INT237419 Binding of Hif1a and Bace1 Positive_regulation of Bace1 1 0.06 1.2 0.15 24.16
127 INT237420 Binding of Hif1a and Bace1 Positive_regulation of Positive_regulation of Bace1 1 0.06 1.2 0.15 24.16
128 INT354896 Binding of Psen2 and Fancd2 1 0.04 0.75 0.03 22.88
129 INT310229 Binding of INS and SUCLA2 1 0.07 4.69 0 20.92
130 INT237418 Binding of Hif1a and Bace1 1 0.06 1.18 0.15 20.00
131 INT325432 Vsnl1 Positive_regulation of Csf2 1 0.19 1.07 0 17.60
132 INT325430 Vsnl1 Positive_regulation of Vhl-ps1 1 0.03 1.01 0 16.72
133 INT266402 Binding of S100P and Ager 1 0.00 2.25 0.35 16.40
134 INT266403 Negative_regulation of Binding of S100P and Ager 1 0.00 0.74 0.13 16.40
135 INT236362 Binding of Gfap and Itgam 1 0.23 2.31 0.2 15.44
136 INT189200 Binding of CA2 and ITPR3 3 0.03 1.9 0.27 14.84
137 INT268445 Olr1 Positive_regulation of Positive_regulation of Lipa 1 0.01 0.87 0 12.72
138 INT236013 HIST2H2AA3 Regulation of Gene_expression of APP 1 0.01 0 0 12.20
139 INT189203 CHGB Regulation of CA2 1 0.04 0.95 0 9.76
140 INT189201 CHGB Regulation of Localization of CA2 1 0.04 0.95 0 9.76
141 INT331227 Binding of Becn1 and Pink1 1 0.03 1.13 0.05 9.16
142 INT182813 EEF1A2 Negative_regulation of ITGAL 1 0.10 1.53 0.51 8.40
143 INT196434 Binding of Ccne2 and Cdc25a 1 0.01 0.48 0 6.52
144 INT308663 Apoe Regulation of Car2 1 0.02 0.44 0.07 6.32
145 INT201741 Binding of Rhoa and Ngfr 1 0.01 1 0 5.92
146 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 5.00
147 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 5.00
148 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23 5.00
149 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4 5.00
150 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84 5.00
151 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 5.00
152 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
153 INT139190 Binding of Fadd and Fas 4 0.38 2.65 1.71 5.00
154 INT266391 Binding of Ager and S100a1 1 0.01 5.63 1.69 5.00
155 INT111892 Ptger2 Regulation of Ptger1 1 0.08 2.09 1.55 5.00
156 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29 5.00
157 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24 5.00
158 INT140172 Binding of Nqo1 and IgG 5 0.17 6.68 1.2 5.00
159 INT189844 Churc1 Positive_regulation of Cnr2 1 0.01 0.79 1.02 5.00
160 INT199109 Binding of Akt1 and Arhgdia 1 0.02 2.73 0.87 5.00
161 INT73538 Ngf Positive_regulation of Ngfr 2 0.41 1.05 0.85 5.00
162 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78 5.00
163 INT182814 Binding of ICAM1 and PECAM1 2 0.02 3.32 0.77 5.00
164 INT200097 Negative_regulation of Binding of Il1a and Jun 1 0.00 2.76 0.77 5.00
165 INT200093 Binding of Il1a and Jun 1 0.00 2.64 0.76 5.00
166 INT266408 Binding of HMGB1 and Ager 1 0.01 2.57 0.76 5.00
167 INT170127 Binding of ITGAL and PECAM1 2 0.01 2.71 0.75 5.00
168 INT205706 P2rx7 Regulation of Gene_expression of Il18 1 0.21 1.35 0.7 5.00
169 INT187522 ATIC Negative_regulation of Gene_expression of Nos2 1 0.02 1.46 0.7 5.00
170 INT165583 Binding of Bdnf and Ngf 3 0.33 0.81 0.69 5.00
171 INT205702 P2rx7 Regulation of Gene_expression of Il1 1 0.04 1.38 0.67 5.00
172 INT231349 Il10 Negative_regulation of Gene_expression of TNF 2 0.23 1.82 0.67 5.00
173 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65 5.00
174 INT255994 Binding of Ang and Il1rn 1 0.09 1.21 0.63 5.00
175 INT254199 Il10 Positive_regulation of Gene_expression of Socs3 2 0.06 0.75 0.63 5.00
176 INT255997 Binding of Il1rn and H7 1 0.01 1.21 0.63 5.00
177 INT181084 Binding of S100a8 and S100a9 6 0.42 2.91 0.62 5.00
178 INT182819 Binding of CD63 and PECAM1 1 0.00 1.63 0.61 5.00
179 INT182815 Binding of CD63 and ICAM1 1 0.00 1.63 0.61 5.00
180 INT205705 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6 1 0.07 1.42 0.58 5.00
181 INT299004 Binding of Il18 and Il1 1 0.04 1.16 0.58 5.00
182 INT215176 Ptger2 Regulation of Ptger3 2 0.09 1.16 0.56 5.00
183 INT266376 Binding of Ager and Itgam 1 0.00 2.31 0.54 5.00
184 INT204494 Binding of App and Fmr1 1 0.54 4.39 0.54 5.00
185 INT255999 Binding of Ang and H7 1 0.00 0.38 0.54 5.00
186 INT235975 Binding of AQP4 and IgG 2 0.04 4.11 0.53 5.00
187 INT201740 Positive_regulation of Ngf Positive_regulation of Nfkb1 1 0.01 1.07 0.51 5.00
188 INT308656 Pik3r1 Positive_regulation of Nos3 1 0.02 1.8 0.5 5.00
189 INT201727 Ngf Positive_regulation of Nfkb1 1 0.01 1 0.48 5.00
190 INT264136 IFNA1 Positive_regulation of Socs3 1 0.01 0.38 0.46 5.00
191 INT288350 IFNA1 Positive_regulation of Localization of Il6 1 0.01 1.49 0.46 5.00
192 INT198931 Binding of Dlg4 and Lrp8 1 0.06 0.23 0.46 5.00
193 INT264137 IFNA1 Positive_regulation of Socs1 1 0.01 0.38 0.46 5.00
194 INT298999 Binding of Il18bp and Il18 1 0.02 0 0.45 5.00
195 INT189197 RASGRP1 Positive_regulation of JUN 1 0.07 1.26 0.43 5.00
196 INT247599 Tlr4 Positive_regulation of Gene_expression of App 1 0.17 0.39 0.42 5.00
197 INT186385 Binding of TNF and Tnfrsf1b 4 0.30 3.24 0.42 5.00
198 INT189849 Binding of Cd40 and Churc1 Regulation of Gene_expression of Ik 1 0.00 0.73 0.41 5.00
199 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41 5.00
200 INT264135 Socs1 Positive_regulation of Protein_catabolism of TOLLIP 1 0.00 0.33 0.41 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Amyloid Plaque. They are ordered first by their pain relevance and then by number of times they were reported in Amyloid Plaque. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT131296 Positive_regulation of Bace1 208 0.70 170.1 15.79 100.00
2 INT47712 Positive_regulation of App 135 0.69 101.38 28.94 100.00
3 INT29745 Binding of APP 47 0.48 26.49 12.4 100.00
4 INT156489 Positive_regulation of Gene_expression of Bace1 67 0.69 41.07 7.02 100.00
5 INT125079 Negative_regulation of Gene_expression of MAPK8 9 0.39 4.87 1.25 100.00
6 INT15610 Localization of GOPC 223 0.65 68.26 28.7 100.00
7 INT264115 Positive_regulation of Ripk4 2 0.29 3.73 0.17 100.00
8 INT105618 Binding of SEPHS1 4 0.27 5.62 1.14 100.00
9 INT109908 Localization of MAPK8 10 0.73 3.86 2.14 100.00
10 INT179538 Binding of Sephs1 3 0.08 2.27 0.25 100.00
11 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 100.00
12 INT179534 Localization of Sephs1 1 0.12 0.76 0.1 100.00
13 INT179540 Phosphorylation of Sephs1 1 0.10 0.64 0.06 100.00
14 INT170601 Positive_regulation of Gene_expression of GOPC 122 0.43 42.79 11.68 100.00
15 INT17618 Gene_expression of B2M 36 0.66 16.39 6.68 100.00
16 INT179536 Gene_expression of Sephs1 3 0.12 1.37 0.6 100.00
17 INT137835 Binding of CAMK2B 1 0.08 1.38 0.42 99.96
18 INT670 Gene_expression of B2m 31 0.66 27.32 8.49 99.96
19 INT69572 Localization of Prnp 96 0.81 38.11 5.45 99.96
20 INT217389 Negative_regulation of Gene_expression of Bace1 43 0.59 18.57 3.27 99.92
21 INT80685 Gene_expression of MAPK8 90 0.72 51.91 13.36 99.90
22 INT132103 Positive_regulation of Gene_expression of MAPK8 26 0.46 16.54 3.94 99.90
23 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76 99.90
24 INT64110 Positive_regulation of Gene_expression of Nos1 68 0.70 58.11 51.64 99.90
25 INT9784 Binding of B2M 9 0.47 6.18 1.44 99.86
26 INT6849 Localization of IL1B 229 0.81 112.56 69.63 99.84
27 INT12082 Localization of IL6 365 0.81 241.78 105.78 99.84
28 INT197493 Localization of Apoe 61 0.79 27.48 7.06 99.84
29 INT19189 Localization of IL1A 14 0.78 9.02 3.78 99.84
30 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 99.84
31 INT199187 Localization of Hmox1 2 0.78 3.36 1.11 99.84
32 INT19475 Positive_regulation of IL1A 20 0.67 17.99 7.57 99.84
33 INT212510 Binding of Apcs 26 0.48 15.2 0.72 99.84
34 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.84
35 INT44717 Gene_expression of TNFSF14 12 0.75 13.44 3.72 99.84
36 INT65500 Gene_expression of App 605 0.78 429.94 98.31 99.78
37 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62 99.78
38 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 99.78
39 INT62895 Gene_expression of NOSTRIN 51 0.75 28.8 10.68 99.78
40 INT116228 Binding of C1qa 26 0.47 15.72 3 99.76
41 INT105761 Binding of GFAP 13 0.36 14.94 2.32 99.76
42 INT7130 Localization of PLA2G2A 32 0.80 20.4 5.05 99.76
43 INT75932 Binding of Csf2 45 0.37 33.2 8.01 99.76
44 INT38574 Binding of Ache 9 0.47 3.64 1.74 99.76
45 INT14503 Binding of BCHE 13 0.48 3.95 1.85 99.76
46 INT210539 Binding of Ide 11 0.29 6.09 0.52 99.76
47 INT79093 Positive_regulation of Nos1 101 0.70 46.89 59.61 99.74
48 INT124860 Gene_expression of Bace1 330 0.78 157.11 31.65 99.70
49 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59 99.68
50 INT25310 Positive_regulation of Igkv1-35 5 0.55 7.16 0.29 99.68
51 INT58003 Localization of APP 32 0.80 13.75 4.2 99.66
52 INT29743 Negative_regulation of App 91 0.59 65.56 31.26 99.64
53 INT4877 Gene_expression of MME 184 0.78 122.82 24.78 99.64
54 INT94122 Negative_regulation of Mmp23 21 0.37 15.81 8.03 99.64
55 INT132997 Localization of Mmp9 59 0.80 45.9 17.61 99.64
56 INT95767 Negative_regulation of Mmp9 72 0.57 49.14 17.1 99.64
57 INT198875 Localization of Mmp23 4 0.07 2.05 0.88 99.64
58 INT111066 Regulation of Bace1 40 0.61 31.47 4.28 99.62
59 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 99.62
60 INT107916 Protein_catabolism of App 114 1.00 66.71 12.38 99.60
61 INT179539 Positive_regulation of Gene_expression of C3 9 0.70 5.98 1.32 99.60
62 INT178198 Gene_expression of C3 62 0.78 39.5 7.69 99.60
63 INT54052 Gene_expression of App 33 0.78 25.08 14.7 99.56
64 INT54055 Regulation of Gene_expression of App 7 0.62 4.04 2.93 99.56
65 INT44954 Gene_expression of APP 191 0.78 105.86 23.9 99.48
66 INT198885 Gene_expression of Lrp1 33 0.57 10.2 1.91 99.48
67 INT210527 Positive_regulation of Gene_expression of Tenc1 14 0.38 6.37 2.45 99.48
68 INT187789 Positive_regulation of Positive_regulation of Bace1 18 0.50 16.18 1.87 99.44
69 INT80690 Positive_regulation of MAPK8 223 0.68 125.63 36.75 99.40
70 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 99.40
71 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 99.40
72 INT43085 Negative_regulation of Ide 28 0.39 19.96 3.45 99.32
73 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77 99.26
74 INT115816 Protein_catabolism of APP 35 0.99 20.14 5.06 99.24
75 INT185240 Binding of Fgf2 14 0.37 7.39 0.59 99.24
76 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 99.20
77 INT188122 Negative_regulation of Hras1 12 0.02 8.38 0.21 99.20
78 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.20
79 INT144830 Positive_regulation of Gene_expression of P2rx7 22 0.68 9.78 3.92 99.20
80 INT73959 Positive_regulation of NOSTRIN 49 0.61 31.1 11.27 99.20
81 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 99.20
82 INT162748 Phosphorylation of Ftcd 1 0.01 1.25 0 99.16
83 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83 99.10
84 INT134914 Binding of Gfap 21 0.37 8.25 3.67 99.10
85 INT756 Gene_expression of C3 138 0.75 100.6 19.2 99.04
86 INT278875 Gene_expression of Apeh 1 0.66 17.41 0.14 99.04
87 INT85966 Gene_expression of Cd40lg 50 0.73 30.9 9.11 99.04
88 INT278862 Positive_regulation of Gene_expression of Apeh 1 0.59 4.49 0.04 99.04
89 INT85971 Positive_regulation of Gene_expression of Cd40lg 14 0.66 7.61 3.29 99.04
90 INT191288 Gene_expression of ABP1 7 0.52 6.61 0.4 99.04
91 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38 99.02
92 INT179550 Phosphorylation of Ywhaq 8 0.03 6.24 1.48 99.00
93 INT3002 Binding of SUGT1 62 0.24 55.9 14.91 99.00
94 INT124250 Binding of APOA4 3 0.18 4.83 0.53 99.00
95 INT3593 Gene_expression of ADRA1D 70 0.75 29.48 20.87 99.00
96 INT123154 Positive_regulation of Gene_expression of Thy1 7 0.53 4.34 0.86 98.98
97 INT99264 Negative_regulation of Gene_expression of Defb42 7 0.23 7.04 5.09 98.96
98 INT99262 Gene_expression of Defb42 16 0.31 9.99 7.38 98.96
99 INT21678 Negative_regulation of B2m 20 0.55 10.11 3.12 98.84
100 INT119541 Positive_regulation of Ttr 5 0.58 6.07 0.6 98.80
101 INT186257 Positive_regulation of Transcription of ROS1 2 0.34 0.1 0.03 98.80
102 INT231240 Gene_expression of Fus 2 0.56 20.05 3.9 98.76
103 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6 98.76
104 INT176614 Positive_regulation of Gene_expression of Ccl5 20 0.59 16.2 4.81 98.76
105 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 98.74
106 INT133156 Binding of Cd40 77 0.48 45.92 13.77 98.74
107 INT2732 Gene_expression of VIP 74 0.78 24.57 33.72 98.72
108 INT24191 Binding of VIP 14 0.40 2.16 6.2 98.72
109 INT6063 Positive_regulation of Bche 17 0.66 6.07 3.08 98.72
110 INT59449 Negative_regulation of Timp1 76 0.42 54.86 26.99 98.68
111 INT6098 Binding of NEUROD1 17 0.47 3.4 5.99 98.66
112 INT18681 Gene_expression of Thy1 80 0.71 38.8 5.23 98.64
113 INT60700 Gene_expression of Itgax 93 0.71 51.89 6.57 98.64
114 INT188667 Localization of Cd40lg 5 0.57 3.29 1.07 98.64
115 INT85965 Binding of Cd40lg 26 0.45 16.76 4.52 98.64
116 INT129808 Localization of Defb42 1 0.04 1.32 0.51 98.64
117 INT129806 Negative_regulation of Localization of Defb42 1 0.02 0.64 0.23 98.64
118 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 98.60
119 INT57187 Positive_regulation of Gfap 49 0.69 27.59 11.46 98.60
120 INT25610 Positive_regulation of Gene_expression of Il1 136 0.67 104.43 43.86 98.60
121 INT73450 Gene_expression of Pilra 7 0.05 2.87 0.97 98.60
122 INT144486 Positive_regulation of Tfdp1 4 0.38 3.15 0.13 98.56
123 INT74449 Positive_regulation of B4GALNT1 53 0.30 34.49 14.96 98.56
124 INT67039 Positive_regulation of Cpox 144 0.65 98.4 33.77 98.56
125 INT89661 Gene_expression of Hrec 102 0.21 69.91 39.57 98.56
126 INT89660 Positive_regulation of Gene_expression of Hrec 15 0.17 12.06 7.37 98.56
127 INT26973 Gene_expression of Tenc1 59 0.66 27.19 12 98.52
128 INT126199 Negative_regulation of S100a4 1 0.08 1.45 1.38 98.52
129 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 98.48
130 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 98.44
131 INT211701 Positive_regulation of Mri1 20 0.34 20.64 6.69 98.42
132 INT63042 Binding of Apoe 59 0.48 31.23 5.88 98.40
133 INT38056 Localization of Crp 71 0.78 53.14 17.03 98.40
134 INT258727 Localization of Apcs 2 0.37 2.49 0.28 98.40
135 INT28151 Positive_regulation of CTs 55 0.61 35.09 20.14 98.38
136 INT69570 Binding of Prnp 75 0.48 44.26 4.37 98.36
137 INT133863 Positive_regulation of Protein_catabolism of App 12 0.59 7.53 1.52 98.32
138 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 98.32
139 INT99844 Localization of P2ry1 7 0.74 4.05 2.19 98.30
140 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 98.24
141 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 98.24
142 INT101474 Positive_regulation of Gene_expression of Gfap 61 0.70 38.3 10.35 98.24
143 INT144483 Localization of Tfdp1 3 0.68 2.48 0.49 98.20
144 INT6971 Regulation of St8sia1 9 0.44 3.25 10.04 98.20
145 INT84769 Positive_regulation of St8sia1 10 0.41 7.56 9.86 98.20
146 INT334930 Regulation of Positive_regulation of St8sia1 1 0.12 0.59 0 98.20
147 INT48412 Gene_expression of Apcs 26 0.54 7.16 1.53 98.16
148 INT72182 Gene_expression of Mcpt1 167 0.75 123.7 52.15 98.16
149 INT144484 Gene_expression of Hpgds 4 0.75 3.4 0.29 98.16
150 INT129883 Gene_expression of Dkk1 56 0.77 45.42 12.52 98.16
151 INT130186 Gene_expression of Ccl5 101 0.74 79.96 25.01 98.16
152 INT16794 Binding of App 103 0.48 64.87 19.79 98.08
153 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 98.08
154 INT6484 Binding of IL1B 122 0.47 75.84 35.07 98.08
155 INT19190 Regulation of Localization of IL1B 14 0.50 8.71 4.12 98.08
156 INT220594 Localization of Bace1 48 0.79 20.22 4.16 98.04
157 INT6852 Localization of TNF 883 0.81 705.95 270.84 98.04
158 INT134786 Gene_expression of Adam10 17 0.68 7.61 3.29 98.04
159 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 98.00
160 INT186256 Transcription of ROS1 4 0.39 2.37 0.25 98.00
161 INT110748 Transcription of Tenc1 5 0.30 3.06 0.48 97.98
162 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 97.96
163 INT30887 Negative_regulation of Ngf 56 0.59 32.96 20.86 97.96
164 INT98789 Negative_regulation of Gene_expression of App 54 0.58 40.27 11.15 97.92
165 INT206139 Phosphorylation of KRT20 8 0.48 9.1 0.66 97.88
166 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 97.84
167 INT327363 Negative_regulation of Ttr 8 0.40 8.21 0.82 97.84
168 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51 97.84
169 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41 97.84
170 INT220614 Regulation of Positive_regulation of Bace1 5 0.45 5.32 0.76 97.84
171 INT9695 Negative_regulation of Csf2 41 0.57 31.65 6.28 97.84
172 INT179543 Negative_regulation of Binding of C1qa 2 0.57 1.12 0.2 97.76
173 INT16150 Positive_regulation of NKG7 10 0.69 10.26 1.73 97.76
174 INT5793 Binding of CTS 110 0.48 63.91 40.62 97.76
175 INT21646 Positive_regulation of Npy 40 0.70 31.31 13.57 97.68
176 INT144485 Localization of Hpgds 1 0.60 1.04 0.11 97.64
177 INT155160 Binding of C3 20 0.47 7.77 2.61 97.64
178 INT179532 Protein_catabolism of C3 5 0.26 1.61 0.34 97.64
179 INT198872 Binding of Lrp1 9 0.36 2.73 0.89 97.60
180 INT9246 Positive_regulation of Cat 113 0.70 52.73 18.04 97.56
181 INT95414 Positive_regulation of Alms1 40 0.41 20.3 8.1 97.56
182 INT43719 Positive_regulation of Vegfa 21 0.69 5.15 2.64 97.56
183 INT204737 Negative_regulation of Gene_expression of Prnp 32 0.59 18.96 1.03 97.56
184 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25 97.48
185 INT45975 Positive_regulation of SAA1 17 0.67 19.7 4.15 97.44
186 INT61147 Protein_catabolism of App 3 0.60 3.76 0.63 97.44
187 INT167614 Positive_regulation of Protein_catabolism of App 1 0.30 0.88 0.44 97.44
188 INT167610 Positive_regulation of Protein_catabolism of Bace2 1 0.22 0.88 0.44 97.44
189 INT167613 Positive_regulation of Protein_catabolism of Psenen 1 0.09 0.88 0.44 97.44
190 INT167611 Protein_catabolism of Psenen 1 0.15 0.88 0.43 97.44
191 INT167616 Protein_catabolism of Ppp2cb 1 0.02 0.87 0.42 97.44
192 INT167615 Protein_catabolism of Bace2 1 0.40 0.88 0.42 97.44
193 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26 97.36
194 INT217388 Negative_regulation of Gene_expression of Apoe 11 0.59 6.07 1.4 97.36
195 INT46054 Gene_expression of Decr1 39 0.65 12.82 9.48 97.24
196 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 97.24
197 INT9889 Gene_expression of Alox5 34 0.63 20.83 8.85 97.24
198 INT22194 Gene_expression of Xdh 20 0.75 10.03 2.83 97.24
199 INT6969 Negative_regulation of St8sia1 12 0.42 6.36 12.96 97.24
200 INT26972 Negative_regulation of Tenc1 57 0.57 56.71 16.87 97.20
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