D:Amyloidosis

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pChart

Disease Term
Synonyms AMYLOID DISEASE, Amyloidoses
Documents 924
Hot Single Events 200
Hot Interactions 11

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Amyloidosis. They are ordered first by their relevance to Amyloidosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT166214 Binding of CTS and TTR 1 0.13 1.63 0.55 99.96
2 INT92045 Binding of ALB and SERPINA1 1 0.30 1.37 0.64 99.36
3 INT297347 Binding of MEFV and SAA@ 1 0.03 1.33 0 98.68
4 INT317832 Binding of Mefv and Il1 1 0.03 3.89 0.7 95.88
5 INT317831 Binding of Mefv and Nlrx1 1 0.00 1.77 0.2 95.88
6 INT85816 Binding of CEL and TTR 1 0.39 0.77 0.14 94.96
7 INT327792 Binding of IGFALS and Alms1 1 0.00 1.15 0.11 92.72
8 INT256586 Binding of RBP4 and TTR 1 0.07 1.92 0.18 89.16
9 INT61410 CTS Positive_regulation of Prl 1 0.02 1.49 0.87 82.88
10 INT212526 Binding of PROC and Apcs 1 0.01 2.54 0 81.20
11 INT137834 Binding of CAMK2B and CTS 1 0.05 1.38 0.42 81.04
12 INT141881 Binding of MECOM and Tnfrsf1a 1 0.00 1.17 0.13 78.72
13 INT220117 Il6 Positive_regulation of TNF 1 0.01 2.45 0.63 78.12
14 INT224922 Binding of FAP and TARM1 1 0.06 1.4 0.06 78.00
15 INT117202 Binding of GFER and Mefv 1 0.03 2.01 0.28 76.48
16 INT242847 Binding of CDB2 and TGFBI 1 0.17 0.56 0 75.12
17 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 69.72
18 INT275670 Binding of HBP1 and DEFB103A 1 0.03 0.23 0.09 67.60
19 INT150393 Binding of CASP1 and MEFV 2 0.16 2.48 0.45 64.32
20 INT334879 CASP1 Regulation of IL1B 1 0.03 1.63 0.31 63.12
21 INT189200 Binding of CA2 and ITPR3 3 0.03 1.9 0.27 62.12
22 INT189203 CHGB Regulation of CA2 1 0.04 0.95 0 57.04
23 INT189201 CHGB Regulation of Localization of CA2 1 0.04 0.95 0 57.04
24 INT182096 Positive_regulation of Binding of Il6 and Il1 2 0.09 4.26 1.31 56.52
25 INT187795 Positive_regulation of Binding of Tnf and Il1 1 0.13 1.87 0.48 56.52
26 INT128221 Binding of IL6ST and Il6 2 0.00 0.73 0.17 55.76
27 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55 55.20
28 INT187796 Binding of Tnf and Il1 1 0.09 1.85 0.48 55.20
29 INT238460 Binding of TGFBI and MLLT4-AS1 1 0.01 0.2 0.06 53.44
30 INT286476 Binding of App and Itm2b 1 0.47 5.24 0.14 51.80
31 INT205135 Binding of APOE and APP 1 0.05 0.35 0.08 50.00
32 INT224921 Binding of TTR and TARM1 1 0.06 1.06 0 48.24
33 INT279265 Binding of MEFV and NLRP3 1 0.07 2.79 0.28 45.36
34 INT317834 Binding of Pstpip1 and Il1 1 0.00 2.03 0.48 43.20
35 INT278379 Binding of Pstpip1 and Mefv 3 0.03 2.02 0.48 43.20
36 INT180124 Rhob Positive_regulation of Rock1 1 0.14 0 0 41.24
37 INT180125 Rhoa Positive_regulation of Rock1 1 0.14 0 0 41.24
38 INT243110 Pprc1 Negative_regulation of Ncoa2 1 0.00 0.52 0.03 40.72
39 INT243108 Pprc1 Negative_regulation of Ncoa1 1 0.00 0.53 0.03 40.72
40 INT243109 Pprc1 Negative_regulation of Pias1 1 0.00 0.51 0.03 40.72
41 INT317835 Nlrp3 Positive_regulation of Il18 1 0.08 1.49 0.31 39.92
42 INT229785 Binding of RAB7A and SPTLC1 1 0.40 1.5 0.27 34.00
43 INT188432 Negative_regulation of Binding of ABCA1 and IL6 1 0.02 0.47 0.05 25.32
44 INT188431 Binding of ABCA1 and IL6 1 0.02 0.47 0.05 25.32
45 INT128214 Binding of Il6 and Stap1 1 0.00 0 0.04 25.20
46 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66 21.56
47 INT220623 Binding of Stat1 and Bace1 11 0.25 10.33 3.81 10.28
48 INT352497 AGT Positive_regulation of Binding of CRS 1 0.14 0.87 0.11 8.88
49 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28 7.52
50 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
51 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
52 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 5.00
53 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84 5.00
54 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41 5.00
55 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21 5.00
56 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09 5.00
57 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91 5.00
58 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54 5.00
59 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29 5.00
60 INT140172 Binding of Nqo1 and IgG 5 0.17 6.68 1.2 5.00
61 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 5.00
62 INT317836 Binding of Fibp and Pycard 1 0.00 2.68 0.98 5.00
63 INT277832 Binding of TNFRSF1B and NPEPPS 1 0.01 1.1 0.88 5.00
64 INT277831 Binding of TNFRSF1A and NPEPPS 1 0.01 1.1 0.87 5.00
65 INT167431 Binding of APP and MYO1C 1 0.23 1.38 0.83 5.00
66 INT335644 CTSB Positive_regulation of F2RL1 1 0.02 2.58 0.82 5.00
67 INT34772 GH1 Regulation of IGF1 2 0.32 0.95 0.69 5.00
68 INT110835 Binding of SPTLC2 and SPTLC1 2 0.42 1.36 0.68 5.00
69 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66 5.00
70 INT220145 HPSE Negative_regulation of Gene_expression of CRH 1 0.01 0.92 0.64 5.00
71 INT352496 AVP Regulation of Gene_expression of CRS 1 0.27 2.47 0.59 5.00
72 INT235975 Binding of AQP4 and IgG 2 0.04 4.11 0.53 5.00
73 INT189197 RASGRP1 Positive_regulation of JUN 1 0.07 1.26 0.43 5.00
74 INT352972 IL4 Negative_regulation of Gene_expression of IL8 1 0.07 1.01 0.43 5.00
75 INT352986 IL10 Negative_regulation of Gene_expression of Il6 1 0.01 1 0.43 5.00
76 INT352985 IL4 Negative_regulation of Gene_expression of Il6 1 0.01 1 0.43 5.00
77 INT335643 CTSB Positive_regulation of PAR4 1 0.01 1.3 0.41 5.00
78 INT352970 IL4 Negative_regulation of Positive_regulation of TH1L 1 0.01 0.91 0.4 5.00
79 INT110834 Binding of AGXT and SPTLC2 2 0.27 0.71 0.36 5.00
80 INT353020 Binding of CD80 and Positive_regulation of Gene_expression of CD28 1 0.13 0.35 0.34 5.00
81 INT327366 Binding of Fap and Ttr 1 0.33 2.9 0.28 5.00
82 INT279266 CADPS Positive_regulation of Regulation of IL1B 1 0.22 1.43 0.28 5.00
83 INT317833 Nlrp3 Positive_regulation of Localization of Il1 1 0.06 1.38 0.26 5.00
84 INT220635 Binding of Lrp1 and Kat5 2 0.09 0.71 0.25 5.00
85 INT198926 Binding of Apbb1 and Lrp1 5 0.12 2.18 0.24 5.00
86 INT320153 Negative_regulation of Binding of IL6 and IL6R 1 0.02 0.37 0.24 5.00
87 INT189199 JUN Positive_regulation of KRT16 1 0.31 0.58 0.22 5.00
88 INT189196 RASGRP1 Positive_regulation of SP1 1 0.05 0.63 0.21 5.00
89 INT220146 Binding of IGF1 and IGFBP1 2 0.10 1.57 0.19 5.00
90 INT139848 Binding of Bace1 and Bace2 2 0.28 0.31 0.18 5.00
91 INT193695 Il2 Positive_regulation of Ctla4 1 0.01 1.63 0.18 5.00
92 INT231244 Binding of Fus and Alms1 1 0.20 0.57 0.17 5.00
93 INT327789 Binding of IgG and Alms1 1 0.01 1.1 0.17 5.00
94 INT327790 Binding of Nqo1 and Alms1 1 0.00 1.1 0.17 5.00
95 INT327791 Binding of AQP4 and Alms1 1 0.03 1.1 0.17 5.00
96 INT279267 Binding of RIPK2 and Positive_regulation of Gene_expression of CASP1 1 0.26 1.12 0.14 5.00
97 INT331628 Binding of HLA-DQA2 and Pain1 1 0.01 2.13 0.14 5.00
98 INT331627 Binding of HLA-DRB3 and Pain1 1 0.00 2.15 0.14 5.00
99 INT193693 Binding of Myd88 and Pain1 1 0.14 0.82 0.13 5.00
100 INT184704 Binding of Prrx2 and Sr1 1 0.21 1.65 0.13 5.00
101 INT220147 IGFBP3 Positive_regulation of IGF1 1 0.10 0.53 0.13 5.00
102 INT220115 Mefv Regulation of Gene_expression of Il1 1 0.01 1.85 0.13 5.00
103 INT139849 Binding of App and Bace1 7 0.41 0.85 0.13 5.00
104 INT220639 Binding of Apbb1 and Ighd 1 0.12 0.31 0.12 5.00
105 INT331612 ETV4 Positive_regulation of Gene_expression of TGFB1 1 0.00 1.32 0.12 5.00
106 INT220622 App Positive_regulation of Rip 2 0.14 0.24 0.12 5.00
107 INT220633 Binding of Kat5 and Ighd 1 0.09 0.32 0.12 5.00
108 INT193697 Apaf1 Positive_regulation of CASP9 1 0.02 1.84 0.12 5.00
109 INT220114 Tnfrsf1a Positive_regulation of Esr1 1 0.14 1.14 0.1 5.00
110 INT220149 Binding of IGF1 and IGFALS 2 0.39 0.44 0.1 5.00
111 INT221068 Cd79a Regulation of Gene_expression of IgG 1 0.01 0.93 0.1 5.00
112 INT221067 Cd79a Regulation of IgG 1 0.01 0.93 0.1 5.00
113 INT221066 Cd79a Regulation of Gene_expression of Ighm 1 0.01 0.93 0.1 5.00
114 INT220116 Tnfrsf1a Negative_regulation of TNF 1 0.06 0.56 0.09 5.00
115 INT262702 Bace1 Positive_regulation of Aplp2 1 0.14 0.25 0.09 5.00
116 INT262701 App Positive_regulation of Aplp2 1 0.12 0.25 0.09 5.00
117 INT262705 App Positive_regulation of Aplp1 1 0.13 0.25 0.09 5.00
118 INT295005 Binding of TNFRSF11A and Tnfsf11 3 0.20 2.02 0.09 5.00
119 INT189195 Binding of C4A and C4B 1 0.14 2.45 0.09 5.00
120 INT262704 Bace1 Positive_regulation of Aplp1 1 0.15 0.25 0.09 5.00
121 INT193691 Positive_regulation of Positive_regulation of Bcr 1 0.01 0.07 0.08 5.00
122 INT193692 IgG2a Positive_regulation of Bcr 1 0.02 0.07 0.08 5.00
123 INT193694 IgG2a Positive_regulation of Tlr9 1 0.05 0.07 0.08 5.00
124 INT295003 Binding of Tnfrsf11b and Tnfsf11 3 0.22 1.85 0.08 5.00
125 INT331626 Edn1 Positive_regulation of Itk 1 0.00 0.57 0.07 5.00
126 INT220629 Gene_expression of Bace1 Positive_regulation of Localization of Il1r2 1 0.17 0.19 0.07 5.00
127 INT331629 Binding of TGFB1 and Positive_regulation of Gene_expression of Itk 1 0.00 0.84 0.07 5.00
128 INT297246 Binding of Notch1 and Ncstn 1 0.04 0.32 0.07 5.00
129 INT297244 Regulation of Binding of Notch1 and Ncstn 1 0.05 0.32 0.07 5.00
130 INT220638 Gene_expression of Bace2 Positive_regulation of Localization of Il1r2 1 0.13 0.19 0.07 5.00
131 INT189202 Binding of C4B and HAS2 1 0.02 1.25 0.05 5.00
132 INT203638 Binding of MR1 and GOPC 1 0.04 1.43 0.05 5.00
133 INT321891 Dkk1 Negative_regulation of Wnt2 1 0.12 0.94 0.05 5.00
134 INT295006 Binding of TNFRSF11A and Tnfrsf11b 2 0.10 1.6 0.04 5.00
135 INT189198 Binding of C4A and SERPINF1 1 0.12 1.17 0.04 5.00
136 INT296893 Nps Negative_regulation of Gene_expression of REN 1 0.00 1.05 0.04 5.00
137 INT321890 Slc3a2 Regulation of Dkk1 1 0.01 0.93 0.04 5.00
138 INT354896 Binding of Psen2 and Fancd2 1 0.04 0.75 0.03 5.00
139 INT199159 Binding of RET and Pheo 1 0.04 1.42 0.03 5.00
140 INT220625 Negative_regulation of Binding of App and Bace1 1 0.44 0.09 0 5.00
141 INT220631 Gene_expression of Gga1 Positive_regulation of Bace1 2 0.24 0 0 5.00
142 INT193696 Binding of CD8A and Trav6-3 1 0.00 0.85 0 5.00
143 INT212522 Binding of Crp and Cd209a 1 0.00 0.8 0 5.00
144 INT297245 Prnp Positive_regulation of Notch1 1 0.21 0.73 0 5.00
145 INT217402 Binding of Bace1 and PSENEN 1 0.02 0.72 0 5.00
146 INT243106 Binding of Crebbp and Src 1 0.05 0.52 0 5.00
147 INT217399 Binding of Bace1 and Ncstn 1 0.05 0.72 0 5.00
148 INT212527 Binding of PROC and Crp 1 0.00 1.5 0 5.00
149 INT331611 NKX2-1 Regulation of Transcription of SFTPB 1 0.01 0.49 0 5.00
150 INT220626 Thim Negative_regulation of Positive_regulation of Bace1 2 0.00 0 0 5.00
151 INT273136 Binding of CHED1 and VSX1 1 0.15 0.12 0 5.00
152 INT279268 CARD8 Positive_regulation of CASP1 1 0.32 0.3 0 5.00
153 INT217398 Binding of Psen2 and Bace1 1 0.12 1.44 0 5.00
154 INT262706 Uts2r Positive_regulation of Bace1 1 0.10 0.39 0 5.00
155 INT243107 Binding of Src and Ep300 1 0.06 0.17 0 5.00
156 INT268445 Olr1 Positive_regulation of Positive_regulation of Lipa 1 0.01 0.87 0 5.00
157 INT212524 Binding of Crp and Ighm 1 0.02 0.92 0 5.00
158 INT220634 Binding of Bace1 and Pawr 2 0.06 0.2 0 5.00
159 INT268459 Binding of LDLR and Olr1 1 0.00 0.78 0 5.00
160 INT262710 Binding of Crem and Hif1a 1 0.00 1.85 0 5.00
161 INT262712 Psen1 Regulation of Gene_expression of Bace1 1 0.22 0.07 0 5.00
162 INT180123 Egfl7 Positive_regulation of App 1 0.02 0.07 0 5.00
163 INT217400 Binding of Psen1 and Bace1 1 0.17 1.43 0 5.00
164 INT262709 Binding of Crem and Gtf3a 1 0.00 0.92 0 5.00
165 INT220628 Gene_expression of Gga1 Positive_regulation of App 2 0.22 0 0 5.00
166 INT262703 Mapk14 Positive_regulation of Bace1 1 0.29 0.39 0 5.00
167 INT256587 Binding of ALB and TTR 1 0.35 0.69 0 5.00
168 INT275703 Binding of TTR and Ebf1 1 0.37 0.08 0 5.00
169 INT212525 MSH6 Positive_regulation of Binding of C1qa 1 0.00 0.38 0 5.00
170 INT217396 Binding of Abca1 and App 1 0.26 0.83 0 5.00
171 INT220636 Binding of Lrp1 and Bace1 2 0.32 0.62 0 5.00
172 INT262708 Bace1 Positive_regulation of Gene_expression of App 1 0.44 2.82 0 5.00
173 INT275702 Binding of F3 and DEFB103A 1 0.01 0.16 0 5.00
174 INT262713 App Regulation of Transcription of Bace1 1 0.45 0.31 0 5.00
175 INT262700 Uts2r Regulation of Gene_expression of Bace1 1 0.12 0.21 0 5.00
176 INT243111 Binding of Crebbp and Ep300 1 0.16 0.17 0 5.00
177 INT212523 Binding of C1qa and Apcs 1 0.28 0.38 0 5.00
178 INT268446 Cdk5 Positive_regulation of Cdk5r1 1 0.02 0.58 0 5.00
179 INT212528 Binding of MSH6 and Apcs 1 0.00 0.68 0 5.00
180 INT220630 Binding of Bace1 and Gga1 3 0.25 0.07 0 5.00
181 INT220624 Eif1 Regulation of App 1 0.00 0.1 0 5.00
182 INT217397 Binding of Bace1 and Alph1 1 0.02 0.73 0 5.00
183 INT262707 Bace2 Positive_regulation of Bace1 1 0.33 0.15 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Amyloidosis. They are ordered first by their pain relevance and then by number of times they were reported in Amyloidosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT670 Gene_expression of B2m 31 0.66 27.32 8.49 100.00
2 INT56342 Gene_expression of TTR 34 0.78 16.5 2.05 100.00
3 INT45725 Binding of Pdia3 8 0.47 3.61 4.42 100.00
4 INT17618 Gene_expression of B2M 36 0.66 16.39 6.68 100.00
5 INT75971 Regulation of B2m 7 0.45 3.96 0.37 100.00
6 INT48137 Gene_expression of Saa1 3 0.61 4.36 0.63 100.00
7 INT77674 Positive_regulation of Gene_expression of Saa 11 0.36 11.92 6.09 100.00
8 INT87361 Negative_regulation of TTR 25 0.57 5.74 1.51 100.00
9 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 100.00
10 INT39444 Negative_regulation of Positive_regulation of F2 7 0.59 5.82 1.42 100.00
11 INT5793 Binding of CTS 110 0.48 63.91 40.62 100.00
12 INT146829 Negative_regulation of Mefv 2 0.39 5.73 0.95 100.00
13 INT36311 Protein_catabolism of NEUROD1 1 0.86 0.51 0.09 100.00
14 INT6891 Binding of TTR 72 0.48 22.81 6.51 99.98
15 INT19492 Regulation of B2M 16 0.60 10.97 2.55 99.96
16 INT9784 Binding of B2M 9 0.47 6.18 1.44 99.96
17 INT13409 Gene_expression of NEUROD1 52 0.75 14.17 12.23 99.96
18 INT56985 Gene_expression of MEFV 56 0.71 46.71 9.47 99.92
19 INT3058 Gene_expression of IGKV2-19 3 0.58 4.02 0.81 99.90
20 INT6019 Positive_regulation of NEUROD1 37 0.67 17.3 8.89 99.88
21 INT21782 Negative_regulation of B2M 11 0.46 5.49 1.92 99.84
22 INT78659 Gene_expression of Thim 17 0.28 14.34 4.4 99.84
23 INT313892 Localization of CADPS 1 0.48 2.37 0.2 99.84
24 INT10207 Gene_expression of PADI4 22 0.75 23.49 1.74 99.80
25 INT49284 Regulation of MYOM2 2 0.08 3.27 0.13 99.80
26 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 99.78
27 INT38327 Negative_regulation of F10 2 0.02 0.8 0.67 99.72
28 INT212510 Binding of Apcs 26 0.48 15.2 0.72 99.68
29 INT65500 Gene_expression of App 605 0.78 429.94 98.31 99.66
30 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62 99.66
31 INT39212 Binding of Ttr 14 0.48 9.62 2.31 99.66
32 INT16923 Positive_regulation of Tnni3 32 0.50 25.01 5.44 99.66
33 INT44223 Positive_regulation of TTR 10 0.70 10.98 1.95 99.64
34 INT125392 Regulation of Mefv 3 0.45 7.2 1.06 99.64
35 INT846 Positive_regulation of B2M 42 0.70 29.78 8.06 99.62
36 INT131296 Positive_regulation of Bace1 208 0.70 170.1 15.79 99.56
37 INT47712 Positive_regulation of App 135 0.69 101.38 28.94 99.56
38 INT25152 Gene_expression of SAA1 37 0.75 53.56 8.07 99.52
39 INT192761 Positive_regulation of Gene_expression of SAA1 5 0.40 7.45 0.82 99.52
40 INT137572 Gene_expression of Maz 3 0.66 10.9 0.85 99.48
41 INT45975 Positive_regulation of SAA1 17 0.67 19.7 4.15 99.44
42 INT117158 Positive_regulation of Localization of B2m 1 0.41 0.94 0.09 99.44
43 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64 99.32
44 INT39443 Positive_regulation of Positive_regulation of F2 6 0.70 4.31 1.3 99.32
45 INT209501 Gene_expression of CADPS 15 0.65 20.7 2.22 99.32
46 INT77675 Gene_expression of Saa 40 0.58 43.37 18.69 99.28
47 INT130187 Negative_regulation of Gene_expression of B2m 2 0.35 1.61 0.33 99.16
48 INT2837 Regulation of PAEP 17 0.53 7.84 3.17 99.16
49 INT149404 Positive_regulation of MAG 1 0.01 1.65 0.12 99.12
50 INT637 Positive_regulation of MRAP 23 0.67 21.13 9.97 99.08
51 INT125391 Gene_expression of Rim5 2 0.01 1.94 0.11 99.04
52 INT125390 Positive_regulation of Gene_expression of Rim5 1 0.00 1.15 0.11 99.04
53 INT137573 Binding of Maz 2 0.31 3.78 0.38 98.92
54 INT25464 Binding of SAA1 11 0.42 6.89 3.72 98.92
55 INT1901 Binding of Mefv 24 0.48 32.26 4.5 98.76
56 INT163165 Phosphorylation of Mefv 2 0.32 0.86 0.26 98.72
57 INT137574 Positive_regulation of Gene_expression of Maz 2 0.42 4.67 0.41 98.68
58 INT77677 Positive_regulation of Saa 30 0.49 33.19 11.18 98.64
59 INT36149 Positive_regulation of Positive_regulation of B2m 1 0.49 0.78 0.19 98.64
60 INT12890 Gene_expression of Ttr 15 0.63 7.68 1.6 98.58
61 INT19023 Localization of B2m 6 0.75 5.15 0.46 98.58
62 INT677 Positive_regulation of CST3 20 0.67 17.47 6 98.56
63 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 98.56
64 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 98.52
65 INT45976 Positive_regulation of SAA@ 2 0.67 2.26 0.4 98.48
66 INT71794 Binding of SERPINC1 17 0.39 10.5 2.64 98.44
67 INT88640 Localization of TTR 5 0.75 1.71 0.3 98.44
68 INT189226 Protein_catabolism of GSN 3 0.54 7.1 1.7 98.36
69 INT189230 Gene_expression of GSN 12 0.75 25.04 7.6 98.36
70 INT60750 Gene_expression of HNF4A 12 0.65 8.29 2.68 98.32
71 INT60751 Positive_regulation of Gene_expression of HNF4A 2 0.49 3.5 0.19 98.32
72 INT21678 Negative_regulation of B2m 20 0.55 10.11 3.12 98.20
73 INT103274 Regulation of SEC14L2 2 0.23 0.98 0.19 98.20
74 INT18844 Binding of IAPP 11 0.36 11.01 1.45 98.12
75 INT636 Binding of MRAP 54 0.48 40.36 18.77 98.08
76 INT23171 Negative_regulation of NLRP3 7 0.37 4.15 1.53 98.04
77 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 98.00
78 INT77490 Positive_regulation of Tnnc1 85 0.68 43.54 9.07 97.88
79 INT149405 Binding of MAG 1 0.01 1.65 0.13 97.84
80 INT30817 Gene_expression of Th 142 0.76 33.56 38.12 97.76
81 INT39500 Positive_regulation of Positive_regulation of Pth 14 0.48 9.75 1.28 97.60
82 INT150395 Binding of MEFV 55 0.44 31.18 3.42 97.48
83 INT37661 Negative_regulation of SERPINC1 48 0.59 38.6 4.77 97.42
84 INT184742 Binding of MAP2 6 0.37 3.29 0.06 97.40
85 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 97.36
86 INT244159 Transcription of NLRP3 3 0.64 5.61 0.39 97.28
87 INT278301 Gene_expression of HDLBP 2 0.08 3.09 0.37 96.92
88 INT50490 Regulation of PTGS2 80 0.48 39.51 25.85 96.92
89 INT22067 Positive_regulation of IL2RB 11 0.70 5.74 1.23 96.92
90 INT35609 Negative_regulation of F10 37 0.57 17.15 4.41 96.88
91 INT1753 Gene_expression of Ache 38 0.78 15.31 4.58 96.76
92 INT673 Positive_regulation of B2m 24 0.68 24.24 4.82 96.72
93 INT100759 Localization of Tnnc1 9 0.55 1.5 0.36 96.68
94 INT46320 Negative_regulation of Ttr 4 0.15 2.54 1 96.60
95 INT220584 Phosphorylation of Bace1 9 0.81 1.31 0.17 96.48
96 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 96.36
97 INT8684 Positive_regulation of ANGPTL5 45 0.69 36.29 7.47 96.36
98 INT64223 Regulation of Xpnpep1 3 0.27 3.13 0.68 96.34
99 INT68675 Regulation of APCS 10 0.62 7.61 3.01 96.32
100 INT256602 Regulation of Gene_expression of TTR 1 0.38 0.31 0 96.20
101 INT256599 Regulation of Binding of TTR 2 0.38 0.31 0 96.20
102 INT313894 Transcription of CADPS 1 0.44 2.72 0.19 96.04
103 INT35109 Binding of SUCLA2 6 0.32 5.79 2.01 96.00
104 INT165342 Gene_expression of TGFBI 13 0.59 5.81 0.39 95.92
105 INT156488 Binding of Bace1 46 0.48 15.64 3.04 95.80
106 INT258962 Protein_catabolism of Saa 1 0.43 1.47 0.44 95.80
107 INT275696 Positive_regulation of Gene_expression of TTR 1 0.35 0.24 0.15 95.76
108 INT335647 Gene_expression of OSMR 1 0.48 2.78 0.72 95.72
109 INT91100 Binding of SPTLC1 10 0.47 12.85 5.71 95.64
110 INT28151 Positive_regulation of CTs 55 0.61 35.09 20.14 95.56
111 INT86639 Gene_expression of KRT16 19 0.68 12.44 7.79 95.56
112 INT219610 Protein_catabolism of SAA1 2 0.90 4.47 0.54 95.44
113 INT106745 Localization of CRP 65 0.81 66.44 15.21 95.32
114 INT192762 Localization of SAA1 10 0.78 12.63 1.44 95.32
115 INT274467 Gene_expression of Saa2 1 0.51 1.9 0.2 95.28
116 INT139321 Positive_regulation of Saa2 5 0.48 6.64 0.54 95.28
117 INT126323 Regulation of TGFBI 6 0.59 3.17 2.9 95.28
118 INT1873 Gene_expression of MRAP 51 0.76 31.75 13.92 95.20
119 INT67374 Gene_expression of Mefv 15 0.74 49.1 8.07 95.16
120 INT77258 Regulation of SAA1 4 0.54 1.93 0.53 94.92
121 INT8798 Positive_regulation of Csrp1 61 0.69 63.86 14.14 94.84
122 INT192423 Positive_regulation of TARM1 5 0.34 10.77 0.51 94.76
123 INT36150 Negative_regulation of Positive_regulation of B2m 1 0.37 0.38 0.1 94.72
124 INT17417 Positive_regulation of Ighd 16 0.69 24.29 2.8 94.68
125 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 94.64
126 INT19967 Gene_expression of C9orf3 18 0.75 26.51 4.6 94.60
127 INT23257 Regulation of CRP 127 0.62 100.05 21.87 94.60
128 INT274466 Positive_regulation of Saa1 1 0.37 1.77 0.2 94.56
129 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 94.48
130 INT178239 Binding of Vhl-ps1 5 0.28 1.83 0.49 94.48
131 INT84572 Gene_expression of Zmat3 67 0.07 37.61 5.86 94.36
132 INT6098 Binding of NEUROD1 17 0.47 3.4 5.99 94.32
133 INT186483 Negative_regulation of MYOM2 3 0.04 2.92 0.79 94.32
134 INT116228 Binding of C1qa 26 0.47 15.72 3 94.32
135 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 94.16
136 INT233453 Gene_expression of Itm2b 8 0.74 8.45 0.99 94.16
137 INT57545 Positive_regulation of Positive_regulation of Ighd 1 0.15 1.78 0.24 93.88
138 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 93.84
139 INT48412 Gene_expression of Apcs 26 0.54 7.16 1.53 93.72
140 INT6852 Localization of TNF 883 0.81 705.95 270.84 93.68
141 INT169987 Transcription of GOPC 45 0.60 21.88 2.61 93.68
142 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 93.52
143 INT103834 Regulation of RETNLB 4 0.04 3.87 1.02 93.48
144 INT15511 Gene_expression of Tnfrsf1a 84 0.76 63.3 24.03 93.16
145 INT135319 Positive_regulation of Positive_regulation of CRP 20 0.50 26.45 5.61 92.96
146 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83 92.92
147 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 92.84
148 INT68702 Negative_regulation of C4bp 6 0.57 7.44 0.5 92.68
149 INT212511 Negative_regulation of Negative_regulation of C4bp 1 0.21 0.85 0 92.68
150 INT236277 Positive_regulation of Gene_expression of CADPS 5 0.42 9.17 1.29 92.44
151 INT273150 Regulation of CHED1 1 0.24 0.09 0 92.44
152 INT4596 Positive_regulation of SCD 18 0.42 22.59 3.26 92.36
153 INT15982 Positive_regulation of NLRP3 25 0.65 23.19 3.57 92.32
154 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 92.28
155 INT120550 Negative_regulation of Rock1 27 0.42 18.38 5.66 92.04
156 INT79191 Positive_regulation of Gene_expression of B2M 3 0.03 2.11 1.08 91.68
157 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 91.48
158 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 91.44
159 INT174653 Localization of MEFV 15 0.70 12.06 1.93 91.44
160 INT183144 Positive_regulation of Localization of MEFV 2 0.42 2.61 0.51 91.44
161 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97 91.04
162 INT11634 Regulation of SERPINE1 24 0.62 20.06 4.26 91.04
163 INT212514 Binding of C4bp 5 0.46 5.32 0.05 91.00
164 INT15918 Gene_expression of Serpine1 60 0.62 41.73 7.72 90.64
165 INT15920 Regulation of Serpine1 34 0.42 17.36 4.89 90.64
166 INT183147 Positive_regulation of Gene_expression of MEFV 6 0.50 4.67 1.73 90.56
167 INT24453 Binding of NLRP3 18 0.48 13.7 1.93 90.48
168 INT134173 Binding of APLP1 4 0.37 2.41 0.67 90.40
169 INT14850 Binding of Slc3a2 4 0.15 1.5 2.07 90.36
170 INT58186 Gene_expression of ITGA1 10 0.25 3 0.84 90.24
171 INT25608 Regulation of Gene_expression of Il1 37 0.44 27.76 10.1 90.20
172 INT317821 Regulation of Gene_expression of Casp1 1 0.05 1.74 0.24 90.20
173 INT50814 Positive_regulation of Mmp2 72 0.68 51.37 20.42 89.92
174 INT63839 Binding of CRS 31 0.41 34.05 4.7 89.84
175 INT90077 Gene_expression of Casp1 29 0.76 20.79 6.26 89.68
176 INT14681 Negative_regulation of GCG 31 0.57 13.55 4.98 89.48
177 INT3593 Gene_expression of ADRA1D 70 0.75 29.48 20.87 89.36
178 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 89.28
179 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 89.20
180 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 89.20
181 INT132662 Binding of Hcm 11 0.31 14.41 0.73 89.12
182 INT68701 Positive_regulation of C4bp 7 0.67 3.02 0.46 88.92
183 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12 88.72
184 INT16428 Positive_regulation of Gtf3a 135 0.20 106.44 26.67 88.68
185 INT952 Negative_regulation of GHRH 57 0.56 25.3 10.34 88.68
186 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 88.36
187 INT43707 Positive_regulation of CCBE1 11 0.07 8.22 4.86 88.36
188 INT180115 Phosphorylation of Rock1 5 0.58 1.21 0.22 88.24
189 INT98224 Negative_regulation of Gene_expression of Cd79a 6 0.35 3.35 1.74 88.04
190 INT220110 Negative_regulation of Gene_expression of Ighd 1 0.13 2.55 0.57 88.04
191 INT163960 Localization of Saa 4 0.49 4.28 1.75 87.92
192 INT89198 Transcription of Saa 2 0.45 2.59 1.31 87.92
193 INT67373 Regulation of Gene_expression of Mefv 2 0.39 6.28 0.75 87.84
194 INT39416 Gene_expression of Cd79a 81 0.64 45.17 6.08 87.76
195 INT273159 Gene_expression of CHED1 1 0.36 1.83 0 87.76
196 INT9899 Gene_expression of Vwf 91 0.74 45.06 9.13 87.76
197 INT68087 Regulation of Vwf 9 0.39 8.06 2.36 87.76
198 INT53189 Gene_expression of VSX1 32 0.69 10.59 7.21 87.76
199 INT153297 Regulation of MEFV 6 0.40 11.09 0.71 87.44
200 INT28815 Gene_expression of Ighd 18 0.65 11.02 2.48 87.44
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