D:Amyotrophic Sclerosis

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Als Amyotrophic Lateral Sclerosis, AMYOTROPHIC LATERAL, Amyotrophic Lateral Sclerosis, AMYOTROPHIC LATERAL SCLEROSIS GUAM FORM, AMYOTROPHIC LATERAL SCLEROSIS WITH DEMENTIA, Bulbar Motor Neuron Disease, Bulbar Motor Neurone Disease, Dementia With Amyotrophic Lateral Sclerosis, GEHRIG DISEASE, Gehrig S Disease, Gehrigs Disease
Documents 7
Hot Single Events 5
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Amyotrophic Sclerosis. They are ordered first by their relevance to Amyotrophic Sclerosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT270044 Il10 Positive_regulation of Positive_regulation of Hmox1 1 0.20 1.59 0.53 5.00
2 INT270043 Binding of Ldlr and Hdl1 1 0.01 2.3 0.43 5.00
3 INT270046 Ido1 Positive_regulation of Positive_regulation of Hmox1 1 0.15 0.8 0.27 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Amyotrophic Sclerosis. They are ordered first by their pain relevance and then by number of times they were reported in Amyotrophic Sclerosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT79723 Positive_regulation of Sod2 34 0.70 24.61 3.92 99.72
2 INT22132 Positive_regulation of CAT 41 0.67 18.64 10.67 92.04
3 INT270029 Negative_regulation of Phosphorylation of Sod2 1 0.26 1.3 0.12 91.64
4 INT270035 Phosphorylation of Sod2 1 0.50 1.29 0.12 91.32
5 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 82.60
6 INT141658 Positive_regulation of Gene_expression of Sod2 51 0.69 35.6 3.71 78.76
7 INT124297 Gene_expression of Sod2 112 0.77 65.65 7.64 78.36
8 INT266894 Positive_regulation of Positive_regulation of Sod2 5 0.41 3.26 0.67 75.68
9 INT80223 Positive_regulation of Hmox1 128 0.68 77.71 17.64 71.36
10 INT18322 Negative_regulation of Ins1 132 0.58 88.49 22.59 71.16
11 INT122041 Binding of Ppara 308 0.48 189.17 51.48 70.80
12 INT232667 Binding of Pd 17 0.16 20.76 3.58 49.32
13 INT112003 Localization of ROS1 94 0.73 66.32 12.16 38.16
14 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 26.48
15 INT91147 Positive_regulation of Positive_regulation of Ppara 30 0.69 19.31 5.56 22.60
16 INT4768 Positive_regulation of OPRM1 212 0.70 31.09 164.28 5.00
17 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 5.00
18 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 5.00
19 INT7528 Regulation of OPRM1 100 0.62 20.63 80.57 5.00
20 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33 5.00
21 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69 5.00
22 INT2416 Negative_regulation of MAOA 92 0.59 42.24 36.5 5.00
23 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 5.00
24 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17 5.00
25 INT90792 Localization of Il10 144 0.80 87.88 30.03 5.00
26 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55 5.00
27 INT44954 Gene_expression of APP 191 0.78 105.86 23.9 5.00
28 INT137767 Gene_expression of Eae1 74 0.34 89.32 20.48 5.00
29 INT120446 Positive_regulation of Cnr2 32 0.70 16.3 18.91 5.00
30 INT170308 Gene_expression of Ido1 159 0.75 69.51 15.98 5.00
31 INT80228 Positive_regulation of Gene_expression of Hmox1 68 0.70 62.88 14.01 5.00
32 INT28420 Gene_expression of Ptgds 59 0.78 31.72 12.67 5.00
33 INT178338 Gene_expression of Tbx15 50 0.65 38.65 12.19 5.00
34 INT71633 Negative_regulation of SLC6A3 25 0.59 10.5 10.69 5.00
35 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17 5.00
36 INT49866 Negative_regulation of Parp1 53 0.58 35.37 8.84 5.00
37 INT123813 Positive_regulation of Parp1 74 0.70 65.36 8.56 5.00
38 INT54368 Positive_regulation of VTA1 13 0.59 3.81 8.13 5.00
39 INT141656 Regulation of Eae1 22 0.39 32.62 8.12 5.00
40 INT154094 Negative_regulation of Eae1 25 0.18 30.42 7.89 5.00
41 INT170295 Positive_regulation of Ido1 40 0.67 28.89 7.61 5.00
42 INT121815 Regulation of Positive_regulation of OPRM1 7 0.62 0.75 7.36 5.00
43 INT138799 Regulation of Gene_expression of Ppara 40 0.60 29.42 6.89 5.00
44 INT122896 Negative_regulation of TH 23 0.57 9.27 6.88 5.00
45 INT31582 Gene_expression of Hdl1 103 0.66 118.95 6.42 5.00
46 INT170315 Positive_regulation of Gene_expression of Ido1 50 0.67 25.39 6.06 5.00
47 INT173974 Positive_regulation of Localization of Il10 25 0.68 16.81 5.87 5.00
48 INT154093 Positive_regulation of Gene_expression of Eae1 23 0.20 26.08 5.84 5.00
49 INT4613 Positive_regulation of Sirt1 32 0.67 18.19 5.53 5.00
50 INT52512 Positive_regulation of SLC43A3 21 0.41 5.39 5.27 5.00
51 INT170311 Negative_regulation of Ido1 16 0.48 14.47 4.81 5.00
52 INT240934 Gene_expression of Sirt1 24 0.75 18.77 4.68 5.00
53 INT96504 Negative_regulation of SLC18A2 5 0.36 2.07 4.62 5.00
54 INT183560 Binding of GABRB3 12 0.23 2.59 3.77 5.00
55 INT109558 Binding of Eae1 9 0.25 10.36 3.16 5.00
56 INT178457 Positive_regulation of LIFR 12 0.56 3.98 2.9 5.00
57 INT190081 Gene_expression of Abca1 21 0.65 18.18 2.45 5.00
58 INT50139 Regulation of Gene_expression of Ptgds 6 0.50 3.5 2.39 5.00
59 INT215379 Positive_regulation of Binding of Ppara 15 0.66 8.04 2.36 5.00
60 INT170323 Regulation of Gene_expression of Ido1 11 0.60 8.74 2.33 5.00
61 INT56084 Negative_regulation of SLC43A3 11 0.39 5.39 2.27 5.00
62 INT215378 Protein_catabolism of Ppara 12 0.86 5.12 2.14 5.00
63 INT157400 Gene_expression of Tnfrsf18 15 0.39 7.3 2.13 5.00
64 INT14596 Localization of Ptgds 11 0.73 4.41 2.12 5.00
65 INT53998 Positive_regulation of MAOB 8 0.61 1.22 2 5.00
66 INT199084 Gene_expression of Cd36 31 0.53 16.94 1.94 5.00
67 INT261192 Gene_expression of Niacr1 57 0.67 24.37 1.89 5.00
68 INT258135 Gene_expression of CARTPT 3 0.40 5.25 1.88 5.00
69 INT261186 Positive_regulation of Niacr1 6 0.49 5.28 1.81 5.00
70 INT131818 Binding of Parp1 14 0.46 8.74 1.76 5.00
71 INT63586 Regulation of Parp1 5 0.43 3.28 1.68 5.00
72 INT110906 Binding of Rorb 14 0.48 2.88 1.62 5.00
73 INT80227 Regulation of Gene_expression of Hmox1 12 0.44 11.04 1.61 5.00
74 INT255787 Positive_regulation of Gene_expression of Sirt1 9 0.67 7.61 1.5 5.00
75 INT194854 Regulation of Positive_regulation of Il10 3 0.37 2.55 1.44 5.00
76 INT215380 Positive_regulation of Gene_expression of Cd36 12 0.47 8.51 1.3 5.00
77 INT27536 Gene_expression of Caf 4 0.52 0.41 1.13 5.00
78 INT239302 Positive_regulation of Gene_expression of Abca1 9 0.32 9.1 1.06 5.00
79 INT168065 Binding of Sirt1 13 0.47 4.55 1.02 5.00
80 INT261188 Localization of Niacr1 10 0.73 6.58 0.85 5.00
81 INT220043 Positive_regulation of Positive_regulation of Ido1 2 0.41 1.94 0.83 5.00
82 INT271160 Negative_regulation of SYNE1 1 0.00 0.67 0.81 5.00
83 INT270033 Regulation of Gene_expression of Sod2 5 0.45 2.34 0.63 5.00
84 INT123814 Positive_regulation of Positive_regulation of Parp1 9 0.50 9.32 0.57 5.00
85 INT270030 Negative_regulation of Positive_regulation of Hmox1 3 0.30 2.49 0.47 5.00
86 INT271161 Negative_regulation of Negative_regulation of SYNE1 1 0.00 0.24 0.47 5.00
87 INT270034 Negative_regulation of Positive_regulation of Ido1 1 0.19 2.23 0.42 5.00
88 INT270027 Regulation of Positive_regulation of Ido1 1 0.23 1.17 0.39 5.00
89 INT261194 Positive_regulation of Gene_expression of Niacr1 3 0.49 1.57 0.38 5.00
90 INT270028 Positive_regulation of Localization of Ptgds 2 0.45 0.61 0.36 5.00
91 INT270037 Positive_regulation of Rxrb 1 0.14 0.89 0.31 5.00
92 INT185956 Gene_expression of Adamts4 2 0.58 0.97 0.29 5.00
93 INT270032 Gene_expression of Nmnat1 2 0.72 7.19 0.15 5.00
94 INT270031 Positive_regulation of Gene_expression of Nmnat1 2 0.65 1.73 0.06 5.00
95 INT270038 Positive_regulation of Positive_regulation of Sirt1 2 0.43 0.44 0.03 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox