D:Anal Fistula

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pChart

Disease Term
Synonyms Anal Atresia, Anal Membrane, Anal Stenosis, ANORECTAL MALFORMATIONS, Ectopic Anus, FISTULA IN ANO, Fistula Rectal, High Imperforate Anus, Low Imperforate Anus, Perineal Anus, RECTAL FISTULA
Documents 109
Hot Single Events 2
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Anal Fistula. They are ordered first by their relevance to Anal Fistula and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT326303 Binding of CRP and FKBP4 1 0.15 1.22 0.41 71.92
2 INT193193 Binding of CRS and RAPH1 1 0.12 1.47 0 22.08
3 INT287088 Binding of EEC1 and Vamp3 1 0.09 1.02 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Anal Fistula. They are ordered first by their pain relevance and then by number of times they were reported in Anal Fistula. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT212271 Binding of ARMC9 14 0.27 3.29 0.43 100.00
2 INT193196 Regulation of MNX1 2 0.19 2.53 0.64 86.96
3 INT328203 Positive_regulation of RBL1 1 0.12 2.62 1.12 79.84
4 INT2067 Localization of Ptger1 14 0.47 1.87 4.57 79.40
5 INT28028 Positive_regulation of Localization of Ptger1 1 0.03 0.81 0.12 79.40
6 INT3467 Positive_regulation of Ptger1 28 0.54 10.59 8.93 79.08
7 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64 77.08
8 INT73731 Binding of RAPH1 9 0.33 14.58 0.5 75.68
9 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 68.88
10 INT328201 Localization of RBL1 1 0.12 1.01 0.34 66.48
11 INT127849 Binding of LOC246267 1 0.19 0.94 0.17 60.24
12 INT121677 Gene_expression of Srms 6 0.59 3.15 1.61 58.32
13 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 53.52
14 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 53.52
15 INT193195 Localization of MNX1 1 0.59 1.01 0.03 42.96
16 INT3512 Gene_expression of Igha 9 0.60 7.71 1.13 11.36
17 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
18 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
19 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
20 INT3933 Positive_regulation of PLOD1 128 0.70 30.76 42.03 5.00
21 INT10796 Gene_expression of CYP2B6 131 0.77 30.14 35.27 5.00
22 INT4403 Binding of CYP2B6 113 0.48 21.17 33.83 5.00
23 INT22579 Localization of Efs 35 0.65 2.77 16.05 5.00
24 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 5.00
25 INT184853 Gene_expression of ADHD1 87 0.65 89.2 11.8 5.00
26 INT7378 Negative_regulation of Efs 17 0.37 1.93 7.78 5.00
27 INT22781 Binding of COL7A1 76 0.48 41.59 6.66 5.00
28 INT157932 Positive_regulation of ADHD1 46 0.48 52.18 6.13 5.00
29 INT49805 Positive_regulation of MUC1 56 0.70 44.5 4.56 5.00
30 INT2105 Negative_regulation of Rhd 10 0.41 4.9 3.4 5.00
31 INT51607 Positive_regulation of DES 33 0.67 32.24 3.29 5.00
32 INT10353 Positive_regulation of PGR 34 0.70 21.84 3.28 5.00
33 INT76611 Positive_regulation of Srms 5 0.59 3.21 3.04 5.00
34 INT101246 Gene_expression of Gata6 6 0.68 3.03 2.68 5.00
35 INT169987 Transcription of GOPC 45 0.60 21.88 2.61 5.00
36 INT287307 Binding of ENO1 9 0.48 11.24 2.51 5.00
37 INT105761 Binding of GFAP 13 0.36 14.94 2.32 5.00
38 INT59784 Binding of DES 22 0.47 19.48 2.27 5.00
39 INT47543 Positive_regulation of Chrm3 11 0.38 5.23 2.17 5.00
40 INT76612 Binding of Srms 3 0.42 1.1 1.87 5.00
41 INT149762 Regulation of MAS1 8 0.31 5.34 1.61 5.00
42 INT287309 Positive_regulation of ENO1 5 0.59 5.67 1.52 5.00
43 INT328202 Gene_expression of RBL1 1 0.13 1.84 1.37 5.00
44 INT287308 Negative_regulation of ENO1 5 0.59 4.07 1.24 5.00
45 INT90670 Positive_regulation of KRT1 10 0.44 6.25 1.16 5.00
46 INT134822 Gene_expression of Gja1 18 0.72 4.2 1 5.00
47 INT287087 Localization of EEC1 2 0.61 1.6 0.72 5.00
48 INT183037 Gene_expression of MNX1 12 0.53 4.27 0.69 5.00
49 INT148341 Gene_expression of MAS1 9 0.65 4.19 0.68 5.00
50 INT39865 Regulation of Positive_regulation of PLOD1 2 0.27 0.71 0.66 5.00
51 INT141782 Binding of CEACAM7 5 0.31 3.2 0.45 5.00
52 INT15762 Negative_regulation of asp1 6 0.37 0.71 0.4 5.00
53 INT193199 Gene_expression of RAPH1 6 0.60 4.55 0.36 5.00
54 INT200806 Binding of EEC1 6 0.39 4.24 0.29 5.00
55 INT180599 Gene_expression of EEC1 5 0.63 2.73 0.23 5.00
56 INT114110 Negative_regulation of EEC1 2 0.37 2.35 0.12 5.00
57 INT287082 Gene_expression of Vamp3 1 0.18 0.99 0.11 5.00
58 INT287085 Negative_regulation of Myh9 1 0.21 0.6 0.03 5.00
59 INT193197 Localization of RAPH1 1 0.51 1.2 0 5.00
60 INT193198 Positive_regulation of Binding of DES 1 0.18 0.49 0 5.00
61 INT287083 Binding of Vamp3 1 0.14 1.58 0 5.00
62 INT287084 Regulation of Vamp3 1 0.12 0.71 0 5.00
63 INT287086 Regulation of Gene_expression of EEC1 1 0.36 0.42 0 5.00
64 INT313043 Localization of MAS1 1 0.21 0.13 0 5.00
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