D:Anaplastic Astrocytoma

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Disease Term
Synonyms ANAPLASTIC ASTROCYTOMAS, Astrocytic Glioma, Astrocytic Gliomas, Astrocytoma, Astrocytoma Anaplastic, ASTROCYTOMA CEREBRAL, Astrocytoma Childhood Cerebral, Astrocytoma Fibrillary, ASTROCYTOMA GEMISTOCYTIC, Astrocytoma Grade I, Astrocytoma Grade Ii
Documents 503
Hot Single Events 200
Hot Interactions 41

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Anaplastic Astrocytoma. They are ordered first by their relevance to Anaplastic Astrocytoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT78854 APP Positive_regulation of Localization of IL6 1 0.14 0.79 0.37 100.00
2 INT272363 Binding of Adar and Adarb1 3 0.26 0.76 0.36 99.88
3 INT339333 Binding of TACR1 and TAC4 1 0.48 0.32 1.05 99.84
4 INT128654 ITIH4 Regulation of Gene_expression of CCL16 1 0.02 2.69 1.79 99.64
5 INT67527 MRXS5 Positive_regulation of Gene_expression of IL6 1 0.21 1.5 0.45 99.52
6 INT272364 Gene_expression of Adar Negative_regulation of Adarb1 1 0.31 0.17 0 99.44
7 INT220456 Binding of VCAN and BAG6 1 0.01 3.46 0 99.38
8 INT148593 Binding of Gfap and Vim 1 0.06 1.25 0.13 99.20
9 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87 99.16
10 INT318211 MUC5AC Positive_regulation of Muc4 1 0.17 1.12 0.17 98.56
11 INT318188 MUC5AC Positive_regulation of MUC1 1 0.16 1.12 0.17 98.56
12 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14 98.52
13 INT64720 Regulation of IL1B Positive_regulation of IL6 1 0.36 0.65 0.5 98.52
14 INT220461 Binding of VCAN and EGFR 1 0.00 0.86 0 98.44
15 INT128652 ITIH4 Regulation of Gene_expression of CCR5 1 0.36 1.46 0.93 97.96
16 INT128655 ITIH4 Regulation of Gene_expression of CCR3 1 0.36 1.45 0.92 97.60
17 INT83913 Il1b Positive_regulation of Gene_expression of IL6 1 0.01 0.5 0.41 97.52
18 INT83915 Il1b Positive_regulation of SERPINA3 1 0.02 0.5 0.41 97.52
19 INT83916 Il1b Positive_regulation of IL6 1 0.02 0.5 0.41 97.52
20 INT67529 PTGDS Positive_regulation of Positive_regulation of IL6 1 0.30 0.69 0.29 97.12
21 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48 96.96
22 INT339334 TAC4 Negative_regulation of B3GAT1 1 0.17 0.15 0.53 96.64
23 INT128653 ITIH4 Regulation of Gene_expression of MIP 1 0.23 1.44 0.92 96.44
24 INT342038 Binding of Gdnf and Ntn1 1 0.01 0.78 0 94.96
25 INT342043 Binding of Gdnf and Unc5a 1 0.20 0.78 0 94.12
26 INT342041 Binding of Gfra2 and Unc5a 1 0.27 0.39 0 94.12
27 INT67528 PTGER2 Positive_regulation of Gene_expression of IL6 2 0.10 1.38 0.45 93.24
28 INT242598 Binding of Gdnf and Gfra2 4 0.16 0.38 0.51 92.16
29 INT322360 ma Positive_regulation of Negative_regulation of TNF 1 0.01 1.36 0.09 90.00
30 INT261400 Binding of nt and ADHD1 1 0.00 1.69 0.18 86.12
31 INT322364 ma Positive_regulation of TNF 1 0.01 5.83 0.08 85.16
32 INT220747 Binding of PCa and EGF 1 0.05 1.42 0.8 84.24
33 INT321578 Binding of Plaur and Positive_regulation of Ctsb 1 0.15 0.92 0.12 84.08
34 INT261401 Binding of Gsk3b and ADHD1 1 0.00 1.62 0.18 83.92
35 INT213903 Binding of EGFR and ERBB2 10 0.37 5.03 0.04 83.60
36 INT318209 Sis Negative_regulation of VEGFA 1 0.00 1.09 0.14 81.84
37 INT307586 Binding of EGFR and CDCP1 1 0.01 0.51 0 81.08
38 INT307585 Binding of EGFR and MET 1 0.11 0.52 0 81.08
39 INT307584 Binding of EGFR and IGF1R 1 0.03 0.52 0 81.08
40 INT252896 INS Regulation of Gene_expression of PTTG1 1 0.00 0.47 0 80.52
41 INT253007 Igf1 Regulation of Gene_expression of PTTG1 1 0.03 0.46 0 80.04
42 INT352355 Binding of CNR1 and EGFR 1 0.19 0.76 0.2 78.96
43 INT261394 Nsdhl Negative_regulation of nt 1 0.01 1.69 0.24 74.72
44 INT245078 FGF2 Positive_regulation of CXCR4 1 0.07 1.36 0 71.16
45 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51 69.40
46 INT265652 Binding of CISH and MYCN 1 0.00 0.28 0.28 67.68
47 INT265651 Binding of ITGAL and MYCN 1 0.00 0.46 0.62 66.72
48 INT224135 Binding of ARRB2 and Adora2b 1 0.14 0.07 0.23 66.56
49 INT266398 Binding of S100b and Trp53 1 0.06 0.92 0.07 65.96
50 INT352615 Binding of Mdm4 and Trp53 1 0.30 1.36 0 64.80
51 INT242015 Binding of Mdm2 and Trp53 3 0.16 5.74 0 64.44
52 INT339350 Binding of TAC4 and Nka1 1 0.03 0.06 0.46 63.68
53 INT294908 Pax3 Positive_regulation of Gene_expression of Il1 1 0.03 0.45 0.76 61.92
54 INT294910 Pax3 Regulation of Positive_regulation of Il1 1 0.02 2.03 0.42 61.68
55 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27 61.52
56 INT272018 Binding of TSC1 and Tsc2 1 0.17 0.48 0 61.36
57 INT339337 Binding of SARDH and TACR1 1 0.01 0.06 0.57 60.08
58 INT339335 Binding of MET and TACR1 1 0.06 0.06 0.57 59.88
59 INT345307 CXCL12 Positive_regulation of Gene_expression of MMP15 1 0.00 2.5 0.05 59.84
60 INT339331 Binding of TACR1 and SFTPA1 1 0.04 0.12 1.14 59.44
61 INT337323 KNG1 Positive_regulation of PRKCA 1 0.15 0.17 0.62 59.12
62 INT253005 Binding of Zic2 and Pttg1 1 0.02 0.57 0 59.04
63 INT266383 Binding of Ager and S100b 1 0.01 3.48 0.33 58.92
64 INT211993 Binding of Ppara and Rorb 1 0.00 1.13 0.54 57.80
65 INT318189 MUC5AC Regulation of Gene_expression of VEGFA 1 0.21 1.17 0.22 55.96
66 INT286969 IL2 Regulation of Gene_expression of FOXP3 1 0.04 1.05 0.1 55.40
67 INT286955 IL2 Positive_regulation of Binding of STAT3 and FOXP3 1 0.03 0.63 0.06 55.40
68 INT286965 Binding of STAT3 and FOXP3 1 0.27 1.84 0.19 51.96
69 INT253009 Igf1 Regulation of PTTG1 1 0.03 0.44 0.13 51.72
70 INT253015 Egf Regulation of PTTG1 1 0.02 0.44 0.13 51.72
71 INT266384 Binding of Ager and S100a6 1 0.01 1.32 0.11 51.28
72 INT266415 Binding of ROS1 and S100a6 1 0.02 0.82 0.03 51.28
73 INT339351 Nka1 Positive_regulation of Gene_expression of SFTPA1 1 0.00 0.05 0.59 50.64
74 INT339332 TAC4 Positive_regulation of Gene_expression of SFTPA1 1 0.04 0.05 0.59 50.64
75 INT253018 Binding of PTTG1 and Zic2 1 0.01 0.76 0 50.24
76 INT293056 Binding of ANXA5 and GOPC 1 0.06 0.51 0.19 50.00
77 INT293055 Binding of ANXA5 and PRSS1 1 0.00 0.59 0 50.00
78 INT339347 Nka1 Positive_regulation of Gene_expression of TAC4 1 0.05 0 0.58 49.00
79 INT339349 TAC4 Positive_regulation of Gene_expression of Nka1 1 0.05 0 0.58 49.00
80 INT224136 ARRB2 Positive_regulation of Adora2b 1 0.19 0 0.16 48.32
81 INT220459 Binding of FN1 and VEGFA 1 0.09 1.45 0.05 41.32
82 INT220744 EGF Positive_regulation of Gene_expression of KRT20 1 0.01 1.26 0.9 41.16
83 INT294911 Pax3 Positive_regulation of Il6 1 0.06 1.78 1.14 39.76
84 INT224132 ARRB2 Negative_regulation of Positive_regulation of Adora2b 1 0.14 0.28 0.15 39.76
85 INT261375 Binding of Nsdhl and Pparg 1 0.05 1.03 0.25 38.48
86 INT225648 IL4 Positive_regulation of Gene_expression of IL12A 1 0.06 0.89 0.03 38.16
87 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27 35.44
88 INT325954 Binding of Cttn and Ezr 1 0.22 1.61 0.07 31.60
89 INT252904 Binding of PRKDC and XRCC5 1 0.00 0.14 0 29.36
90 INT253013 Binding of PRKDC and Zic2 1 0.00 0.14 0 29.36
91 INT351676 Fut1 Negative_regulation of Ptk2 1 0.01 4.39 0 27.32
92 INT330491 Binding of Nka1 and SFTPA1 2 0.00 0 0.58 26.44
93 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61 25.00
94 INT253014 Binding of XRCC5 and Zic2 1 0.00 0.14 0 24.96
95 INT271994 Binding of Fkbp1a and Mtor 1 0.00 0.22 0 24.08
96 INT266402 Binding of S100P and Ager 1 0.00 2.25 0.35 21.40
97 INT220738 EGF Regulation of Gene_expression of EGFR 1 0.09 0.6 0.67 21.24
98 INT196210 Binding of L1RE1 and TES 1 0.12 0 0 20.88
99 INT301310 GALE Positive_regulation of GPR17 1 0.00 0 0.03 13.88
100 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 13.12
101 INT271999 Binding of Fkbp1a and Positive_regulation of Negative_regulation of Mtor 1 0.00 0.18 0 13.12
102 INT337327 KNG1 Positive_regulation of BDKRB2 1 0.21 0.4 0.32 12.32
103 INT337326 PIK3CD Positive_regulation of Localization of ITPR3 1 0.02 0 0.43 11.32
104 INT337325 PIK3CD Positive_regulation of Phosphorylation of IL2RG 1 0.00 0 0.43 11.32
105 INT337324 PIK3CD Positive_regulation of Gene_expression of ITPR3 1 0.02 0 0.43 11.32
106 INT325945 Binding of Cd44 and Ezr 1 0.25 0.39 0 10.32
107 INT325942 Binding of Icam1 and Ezr 1 0.15 0.39 0 10.32
108 INT325949 Binding of Spn and Ezr 1 0.14 0.39 0 10.32
109 INT325950 Binding of Icam2 and Ezr 1 0.17 0.39 0 10.32
110 INT245076 CXCR4 Regulation of Gene_expression of VEGFA 1 0.16 1.05 0.03 10.00
111 INT225738 Binding of RANBP9 and Entpd1 1 0.13 0.3 0.42 6.32
112 INT318474 Positive_regulation of OPRM1 Positive_regulation of Localization of CA2 1 0.17 0.55 2.7 5.00
113 INT318473 Positive_regulation of OPRM1 Positive_regulation of CA2 1 0.17 0.46 2.13 5.00
114 INT266391 Binding of Ager and S100a1 1 0.01 5.63 1.69 5.00
115 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57 5.00
116 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53 5.00
117 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35 5.00
118 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18 5.00
119 INT220751 EGF Regulation of GOPC 1 0.08 0 1.18 5.00
120 INT220752 Negative_regulation of EGF Regulation of NAV1 1 0.26 0 1.18 5.00
121 INT220753 Negative_regulation of EGF Regulation of GOPC 1 0.08 0 1.18 5.00
122 INT220748 EGF Regulation of NAV1 1 0.28 0 1.17 5.00
123 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11 5.00
124 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
125 INT314136 Binding of TAC1 and SFTPA1 2 0.03 0.78 1.06 5.00
126 INT36683 Gh1 Regulation of Gnrhr 3 0.08 1.25 0.95 5.00
127 INT265649 TBK1 Negative_regulation of COMT 1 0.01 0.61 0.94 5.00
128 INT306823 Binding of E2F4 and GOPC 1 0.06 0.23 0.91 5.00
129 INT339318 Ngf Positive_regulation of Pik3cg 1 0.02 0.69 0.87 5.00
130 INT306831 Positive_regulation of Binding of E2F4 and NOLC1 1 0.10 0.46 0.85 5.00
131 INT306826 Binding of E2F4 and NOLC1 1 0.08 0.41 0.84 5.00
132 INT220739 EGF Positive_regulation of Transcription of NAV1 1 0.31 0.16 0.83 5.00
133 INT266408 Binding of HMGB1 and Ager 1 0.01 2.57 0.76 5.00
134 INT220746 EGF Positive_regulation of Gene_expression of GOPC 1 0.13 0 0.72 5.00
135 INT294906 Binding of Pax3 and Tac4 1 0.01 1.15 0.71 5.00
136 INT261378 Nsdhl Negative_regulation of Gene_expression of Flvcr2 1 0.01 0.34 0.7 5.00
137 INT181084 Binding of S100a8 and S100a9 6 0.42 2.91 0.62 5.00
138 INT261372 Gsk3b Regulation of Gene_expression of Ifi205 1 0.00 0.24 0.58 5.00
139 INT345303 MMP15 Positive_regulation of MMP13 1 0.00 1.18 0.58 5.00
140 INT345302 MMP15 Positive_regulation of MMP2 1 0.06 1.17 0.57 5.00
141 INT190702 CD40 Positive_regulation of Gene_expression of F3 1 0.00 1.4 0.55 5.00
142 INT266381 Positive_regulation of Ager Positive_regulation of Nfkb1 1 0.00 0.77 0.55 5.00
143 INT266376 Binding of Ager and Itgam 1 0.00 2.31 0.54 5.00
144 INT156517 Binding of CNR1 and FAAH 3 0.38 1.53 0.53 5.00
145 INT328058 IL4 Positive_regulation of FAAH 1 0.29 4.29 0.53 5.00
146 INT345308 Binding of ABCA1 and TIMP2 1 0.00 0.21 0.52 5.00
147 INT220745 EGF Positive_regulation of Positive_regulation of PCa 1 0.05 0.79 0.52 5.00
148 INT318472 CA2 Regulation of OPRM1 1 0.17 0 0.51 5.00
149 INT220741 Binding of EGFR and SOAT1 1 0.02 0.37 0.49 5.00
150 INT36684 Gh1 Regulation of Prl 2 0.18 1.25 0.48 5.00
151 INT345306 Binding of MMP14 and TIMP2 1 0.04 0.21 0.48 5.00
152 INT345301 Binding of MMP14 and TIMP2 Positive_regulation of MMP2 1 0.02 0.21 0.48 5.00
153 INT251297 Binding of C2 and CD4 1 0.04 0.35 0.47 5.00
154 INT306828 Binding of E2F2 and E2F3 1 0.20 0.15 0.46 5.00
155 INT306824 Binding of E2F1 and E2F2 1 0.15 0.15 0.46 5.00
156 INT100726 TNF Positive_regulation of Gene_expression of F2RL1 2 0.27 1.9 0.46 5.00
157 INT263917 Binding of SST and Sstr5 2 0.02 0.56 0.45 5.00
158 INT345305 MMP14 Positive_regulation of MMP13 1 0.00 0.33 0.45 5.00
159 INT345304 MMP14 Positive_regulation of MMP2 1 0.08 0.2 0.45 5.00
160 INT261374 Nsdhl Regulation of Esr2 1 0.05 0.76 0.41 5.00
161 INT261370 Nsdhl Regulation of Esr1 1 0.01 0.75 0.41 5.00
162 INT266393 Binding of Ager and Fn1 1 0.00 0.82 0.39 5.00
163 INT266382 Binding of Col4a1 and Fn1 1 0.00 0.82 0.39 5.00
164 INT266397 Binding of Ager and Col4a1 1 0.00 0.81 0.38 5.00
165 INT266419 HMGB1 Positive_regulation of Ager 1 0.01 1.37 0.37 5.00
166 INT306830 E2F2 Regulation of C1orf61 1 0.02 0.48 0.36 5.00
167 INT306822 Binding of E2F2 and GOPC 1 0.05 0.53 0.35 5.00
168 INT193784 ITIH4 Positive_regulation of YWHAZ 1 0.04 1.21 0.34 5.00
169 INT330377 Positive_regulation of Binding of TLR2 and TLR9 1 0.09 2.79 0.32 5.00
170 INT337412 AKT3 Negative_regulation of Localization of AKT2 1 0.09 0.5 0.32 5.00
171 INT330381 Binding of TLR2 and TLR9 1 0.07 2.77 0.32 5.00
172 INT337418 AKT2 Negative_regulation of Localization of AKT3 1 0.09 0.5 0.32 5.00
173 INT330389 Positive_regulation of Binding of TLR2 and TLR8 1 0.08 2.78 0.32 5.00
174 INT220740 EGF Positive_regulation of Regulation of NAV1 1 0.31 0.61 0.32 5.00
175 INT339324 SARDH Positive_regulation of SFTPA1 Negative_regulation of B3GAT1 1 0.00 0 0.32 5.00
176 INT220749 EGF Positive_regulation of Positive_regulation of KRT20 1 0.01 0.61 0.32 5.00
177 INT337410 AKT3 Negative_regulation of AKT1 1 0.09 0.49 0.32 5.00
178 INT337414 AKT2 Negative_regulation of AKT1 1 0.10 0.5 0.32 5.00
179 INT339322 MET Positive_regulation of SFTPA1 Negative_regulation of B3GAT1 1 0.00 0 0.31 5.00
180 INT145682 Binding of P2rx4 and P2rx7 2 0.25 0.36 0.31 5.00
181 INT339323 SFTPA1 Positive_regulation of SFTPA1 Negative_regulation of B3GAT1 1 0.00 0 0.31 5.00
182 INT330383 Binding of TLR2 and TLR3 1 0.07 2.77 0.31 5.00
183 INT339328 SFTPA1 Negative_regulation of B3GAT1 1 0.01 0 0.31 5.00
184 INT339321 TAC4 Positive_regulation of SFTPA1 Negative_regulation of B3GAT1 1 0.02 0 0.31 5.00
185 INT330378 Positive_regulation of Binding of TLR2 and TLR3 1 0.10 2.78 0.31 5.00
186 INT330387 Binding of TLR2 and TLR8 1 0.06 2.77 0.31 5.00
187 INT266375 S100b Positive_regulation of Ager 1 0.02 1.8 0.31 5.00
188 INT224131 Binding of CAV1 and Agtr1a 1 0.00 0.08 0.3 5.00
189 INT202313 Gene_expression of PDGFB Positive_regulation of Positive_regulation of Pdgfrb 1 0.14 1 0.29 5.00
190 INT294907 Il1 Positive_regulation of Il6 1 0.06 1.45 0.29 5.00
191 INT211997 CORD1 Positive_regulation of Rara 1 0.01 0.68 0.29 5.00
192 INT202314 Gene_expression of PDGFB Positive_regulation of Phosphorylation of Pdgfrb 1 0.14 1 0.29 5.00
193 INT339338 Binding of TAC4 and SFTPA1 1 0.03 0 0.28 5.00
194 INT328064 IL10 Positive_regulation of FAAH 1 0.05 1.48 0.26 5.00
195 INT245072 PPARA Regulation of Gene_expression of CXCR4 1 0.07 0.68 0.26 5.00
196 INT294905 Binding of Hgf and Pax3 1 0.01 1.54 0.25 5.00
197 INT294912 Binding of Pax3 and Tacr3 1 0.01 1.54 0.25 5.00
198 INT225652 Gene_expression of IL4 Positive_regulation of Positive_regulation of IL12A 1 0.06 1.2 0.25 5.00
199 INT266421 Binding of HMGB1 and Il1 1 0.02 0.37 0.24 5.00
200 INT88310 ITIH4 Positive_regulation of CXCR4 2 0.27 1.98 0.23 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Anaplastic Astrocytoma. They are ordered first by their pain relevance and then by number of times they were reported in Anaplastic Astrocytoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT74527 Positive_regulation of PDGFB 14 0.38 13.31 2.54 100.00
2 INT271960 Positive_regulation of Binding of TSC1 1 0.25 0.88 0.03 100.00
3 INT111384 Gene_expression of Adora3 18 0.75 10.53 5.73 100.00
4 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 100.00
5 INT58003 Localization of APP 32 0.80 13.75 4.2 100.00
6 INT214073 Binding of TSC1 9 0.37 22 1.34 99.98
7 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 99.94
8 INT13042 Gene_expression of INA 26 0.78 4.65 6.44 99.86
9 INT37889 Gene_expression of P2ry2 75 0.65 26.01 23.8 99.86
10 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 99.84
11 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 99.84
12 INT122953 Gene_expression of COMT 65 0.77 25.84 40.49 99.84
13 INT144736 Negative_regulation of Gene_expression of COMT 13 0.58 6.47 9.28 99.84
14 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66 99.84
15 INT4742 Gene_expression of Tac1 177 0.78 69.99 102.66 99.84
16 INT27933 Gene_expression of NCOR2 65 0.72 31.35 24.23 99.84
17 INT67098 Regulation of MIB1 3 0.24 4.23 0.42 99.84
18 INT287 Localization of Cck 518 0.81 86.84 364.04 99.84
19 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92 99.84
20 INT6108 Gene_expression of Npy 292 0.78 110.65 148.21 99.84
21 INT397 Localization of SST 232 0.81 58.05 101.19 99.84
22 INT6107 Localization of Npy 180 0.81 26.76 81.67 99.84
23 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 99.84
24 INT67975 Gene_expression of Bdkrb2 38 0.68 21.69 17.94 99.84
25 INT38731 Localization of Trpv1 138 0.81 52.73 90.49 99.84
26 INT61993 Gene_expression of NF1 29 0.78 34.47 1.23 99.76
27 INT96092 Binding of ANXA5 24 0.36 14.51 2.6 99.76
28 INT80019 Regulation of ERBB4 2 0.27 1.52 0.09 99.76
29 INT36855 Gene_expression of P2RY6 19 0.42 6.16 4.45 99.72
30 INT109850 Gene_expression of P2RY4 8 0.65 2.05 1.47 99.72
31 INT105816 Gene_expression of P2RY2 53 0.78 16.47 9.67 99.72
32 INT109848 Gene_expression of P2RY1 26 0.62 6.71 4.98 99.72
33 INT5489 Localization of CA2 172 0.80 39.46 33.56 99.68
34 INT12082 Localization of IL6 365 0.81 241.78 105.78 99.66
35 INT109910 Gene_expression of CCL16 104 0.74 76.1 43.97 99.64
36 INT220433 Gene_expression of RXRB 3 0.14 1.83 0.63 99.64
37 INT265656 Positive_regulation of Gene_expression of RXRB 1 0.04 0.24 0.5 99.64
38 INT103674 Positive_regulation of Gene_expression of CXCR4 32 0.69 37.1 3.08 99.64
39 INT174486 Regulation of Gene_expression of CD4 12 0.36 6.09 1.39 99.64
40 INT193815 Regulation of Gene_expression of CXCR4 17 0.61 20.27 1.15 99.64
41 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.60
42 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 99.60
43 INT61626 Transcription of IL6 73 0.72 42.04 17.86 99.60
44 INT64724 Positive_regulation of Transcription of IL6 26 0.69 13.63 5.96 99.60
45 INT64725 Regulation of Transcription of IL6 9 0.45 7.96 3.49 99.60
46 INT109650 Gene_expression of Aqp4 87 0.78 51.52 20.72 99.60
47 INT36054 Transcription of IL1B 53 0.72 32.64 17.31 99.60
48 INT239093 Gene_expression of PTTG1 84 0.65 83.94 1.87 99.60
49 INT95465 Positive_regulation of P2ry6 4 0.57 2.06 1.61 99.60
50 INT252992 Regulation of Gene_expression of PTTG1 1 0.18 5.07 0.04 99.60
51 INT220468 Positive_regulation of Binding of BAG6 1 0.07 1.28 0 99.54
52 INT220473 Positive_regulation of Binding of VCAN 1 0.07 1.28 0 99.54
53 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 99.52
54 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 99.52
55 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 99.52
56 INT275774 Negative_regulation of Transcription of NGF 1 0.07 0.1 0 99.52
57 INT88322 Gene_expression of CCR5 111 0.78 77.36 39.84 99.48
58 INT89293 Positive_regulation of Gene_expression of CCR5 29 0.70 22.14 15 99.48
59 INT9783 Gene_expression of INSRR 81 0.50 32.99 15.52 99.44
60 INT142435 Gene_expression of NES 86 0.78 47.53 4.92 99.44
61 INT102234 Gene_expression of ESR2 17 0.65 9.29 2.3 99.44
62 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 99.44
63 INT8095 Gene_expression of ERBB3 47 0.77 24.85 2.82 99.40
64 INT8098 Positive_regulation of Gene_expression of ERBB3 7 0.69 3.79 0.1 99.40
65 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97 99.38
66 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34 99.38
67 INT220469 Binding of VCAN 1 0.06 6.24 0.13 99.38
68 INT110638 Negative_regulation of COMT 43 0.59 21.03 21.05 99.36
69 INT92316 Gene_expression of Plaur 30 0.61 22.06 2.21 99.32
70 INT216380 Gene_expression of PAX6 49 0.78 15.63 1.22 99.32
71 INT51486 Negative_regulation of GNPTAB 11 0.41 8.18 1.45 99.28
72 INT84925 Transcription of NGF 11 0.65 4.13 3.65 99.28
73 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72 99.24
74 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 99.24
75 INT220465 Binding of BAG6 7 0.30 6.41 1.07 99.20
76 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52 99.16
77 INT24891 Gene_expression of SYP 55 0.75 45.76 7.53 99.16
78 INT195102 Gene_expression of Cspg4 3 0.60 1.56 0.42 99.16
79 INT195084 Positive_regulation of Gene_expression of Cspg4 2 0.49 0.87 0.25 99.16
80 INT195100 Positive_regulation of Cspg4 2 0.62 0.92 0.19 99.16
81 INT224234 Gene_expression of GPR17 33 0.65 4.25 3.45 99.12
82 INT80017 Gene_expression of ERBB4 10 0.77 6.94 0.26 99.12
83 INT193816 Gene_expression of SYCP3 4 0.65 3.55 1.09 99.12
84 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 99.08
85 INT58390 Negative_regulation of Localization of PTGER2 25 0.21 14.4 4.25 99.00
86 INT35487 Localization of PTGER2 103 0.46 51.24 17.45 99.00
87 INT345318 Transcription of MMP24 1 0.21 2.09 0.18 98.88
88 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37 98.82
89 INT99507 Positive_regulation of Bcl2l1 17 0.69 9.23 4.97 98.82
90 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79 98.82
91 INT6849 Localization of IL1B 229 0.81 112.56 69.63 98.76
92 INT272338 Negative_regulation of Adarb1 4 0.46 8.88 0.43 98.76
93 INT115649 Gene_expression of Camk2a 95 0.78 33.22 38 98.76
94 INT102525 Gene_expression of CCR3 24 0.71 16.19 10 98.68
95 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19 98.68
96 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 98.68
97 INT73594 Positive_regulation of Gene_expression of ISYNA1 61 0.55 31.35 13.45 98.68
98 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23 98.56
99 INT271914 Negative_regulation of Tsc1 5 0.38 3.08 0.04 98.54
100 INT246776 Negative_regulation of Tsc2 18 0.48 6.82 0.12 98.54
101 INT246774 Positive_regulation of Tsc2 6 0.41 2.4 0 98.54
102 INT271927 Positive_regulation of Tsc1 1 0.44 0.4 0 98.54
103 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 98.52
104 INT9210 Regulation of IL6 166 0.62 125.61 49.95 98.52
105 INT64723 Regulation of Positive_regulation of IL6 13 0.61 12.59 5.19 98.52
106 INT268804 Gene_expression of ma 2 0.16 11.97 0.38 98.44
107 INT342035 Gene_expression of Kcnc4 1 0.48 0.59 0 98.44
108 INT144739 Regulation of Gene_expression of COMT 11 0.61 3.07 7.08 98.32
109 INT12464 Binding of MET 38 0.47 10.3 13.15 98.32
110 INT339341 Binding of TAC4 1 0.34 0.32 1.62 98.32
111 INT134207 Gene_expression of Ptk2 56 0.73 31.97 0.78 98.32
112 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 98.20
113 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36 98.16
114 INT69484 Positive_regulation of Gene_expression of OPRM1 75 0.70 12.86 52.27 98.16
115 INT11185 Regulation of Slco1c1 15 0.44 6.88 4.52 98.08
116 INT252961 Localization of Fgf1 3 0.27 5.91 0.35 98.08
117 INT266341 Regulation of Localization of Fgf1 1 0.03 0.92 0.08 98.08
118 INT3948 Regulation of Cck 291 0.62 58.07 255.88 98.00
119 INT5118 Regulation of SST 97 0.62 34.35 51.74 98.00
120 INT5338 Regulation of Npy 92 0.62 25.54 51.24 98.00
121 INT342033 Gene_expression of Unc5a 1 0.69 0.59 0 98.00
122 INT325937 Positive_regulation of Ezr 1 0.50 2.17 0.03 97.96
123 INT11154 Binding of EGFR 149 0.48 96.23 6.29 97.92
124 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95 97.88
125 INT14246 Regulation of Positive_regulation of IL1B 7 0.44 3.04 1.77 97.80
126 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 97.80
127 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37 97.76
128 INT265663 Positive_regulation of Gene_expression of COMT 2 0.50 0.26 0.79 97.76
129 INT99504 Negative_regulation of Bax 19 0.56 8.89 4.44 97.74
130 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 97.68
131 INT62373 Negative_regulation of NGF 34 0.59 25.87 22.38 97.64
132 INT10444 Positive_regulation of Gene_expression of CNR1 18 0.69 8.69 7.84 97.52
133 INT165005 Binding of REST 26 0.43 2.81 1.39 97.48
134 INT28367 Positive_regulation of REST 10 0.54 2.07 1.52 97.48
135 INT272360 Gene_expression of Adar 13 0.61 4.33 0.69 97.44
136 INT66213 Localization of RELA 63 0.78 14.71 8.77 97.44
137 INT272359 Positive_regulation of Gene_expression of Adar 1 0.55 1.47 0 97.44
138 INT6894 Gene_expression of CNR1 168 0.78 74.07 62.84 97.42
139 INT67474 Negative_regulation of B3GAT1 9 0.57 5.43 3.73 97.32
140 INT26058 Gene_expression of SH3BP5 12 0.23 2.81 4.88 97.28
141 INT120843 Gene_expression of CNTN1 7 0.54 4.27 1.06 97.20
142 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 97.04
143 INT19191 Negative_regulation of Localization of IL1B 35 0.58 15.19 13.63 97.00
144 INT45075 Gene_expression of Sugt1 24 0.27 8.5 1.33 97.00
145 INT10304 Binding of OPRK1 89 0.48 9.28 49.42 97.00
146 INT187635 Positive_regulation of SARDH 3 0.12 0.63 0.88 96.92
147 INT189946 Positive_regulation of Gene_expression of Pttg1 14 0.68 23.72 0.38 96.84
148 INT252944 Positive_regulation of Pttg1 1 0.46 2.53 0 96.84
149 INT189948 Gene_expression of Pttg1 106 0.76 104.68 1.41 96.84
150 INT12156 Positive_regulation of MET 43 0.67 17.75 12.64 96.68
151 INT8571 Gene_expression of B3GAT1 54 0.75 36.85 15.98 96.56
152 INT25610 Positive_regulation of Gene_expression of Il1 136 0.67 104.43 43.86 96.56
153 INT22092 Gene_expression of SERPINA3 17 0.75 11.57 3.16 96.48
154 INT83292 Gene_expression of MIP 35 0.75 25.22 10.14 96.44
155 INT310891 Gene_expression of 53T 28 0.50 35.4 7.17 96.44
156 INT120401 Positive_regulation of PIK3CD 33 0.45 14.89 7.37 96.28
157 INT8836 Positive_regulation of SFTPA1 36 0.47 28.37 23.59 96.20
158 INT120335 Gene_expression of SNAP25 24 0.65 9.44 5.83 96.04
159 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 95.92
160 INT127011 Negative_regulation of Gene_expression of CCL4L1 2 0.30 1.43 1.82 95.88
161 INT128657 Negative_regulation of Gene_expression of CCL23 1 0.08 1.43 0.98 95.88
162 INT195085 Gene_expression of S100b 12 0.56 12.26 2.33 95.84
163 INT135629 Binding of COMT 33 0.48 16.68 19.37 95.84
164 INT39050 Positive_regulation of PGF 14 0.49 8.05 1.43 95.76
165 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 95.60
166 INT271930 Gene_expression of Tsc1 1 0.69 6.88 0.04 95.60
167 INT119227 Gene_expression of Tsc2 8 0.68 10.67 0.03 95.60
168 INT271919 Gene_expression of Tsc2 6 0.39 2.23 0 95.60
169 INT6623 Gene_expression of NA 231 0.78 45.78 59.36 95.52
170 INT196241 Gene_expression of L1RE1 1 0.44 0.86 0.57 95.48
171 INT57580 Positive_regulation of TACR1 18 0.69 9.35 12.47 95.48
172 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 95.44
173 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 95.44
174 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 95.28
175 INT77652 Negative_regulation of Gene_expression of IL8 99 0.59 67.57 30.21 95.20
176 INT68216 Binding of NF1 40 0.48 51.24 4.59 95.08
177 INT738 Regulation of POMC 459 0.62 111.19 243.74 95.08
178 INT7585 Regulation of Crh 24 0.58 9.88 12.97 95.08
179 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03 95.04
180 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 95.00
181 INT71682 Gene_expression of CCL4L1 7 0.75 5.51 2.45 94.96
182 INT128656 Gene_expression of CCL23 2 0.55 2.58 1.54 94.96
183 INT207081 Binding of Plaur 6 0.31 5.99 0.41 94.80
184 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 94.80
185 INT4449 Positive_regulation of NA 179 0.55 40.26 37.82 94.76
186 INT89929 Positive_regulation of Positive_regulation of STAT3 22 0.65 9.21 2.54 94.76
187 INT115193 Positive_regulation of Phosphorylation of STAT3 30 0.64 11.37 2.2 94.76
188 INT217168 Gene_expression of MIR21 30 0.55 30.86 0.62 94.56
189 INT217156 Positive_regulation of Gene_expression of MIR21 9 0.49 16.04 0.38 94.56
190 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 94.48
191 INT252 Localization of GH1 529 0.80 227.4 122.05 94.32
192 INT695 Binding of POMC 304 0.48 56.66 126.85 94.24
193 INT19777 Binding of Crh 16 0.40 6.65 4.36 94.24
194 INT55169 Binding of RELA 40 0.36 4.91 1.74 94.12
195 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45 94.08
196 INT91370 Phosphorylation of STAT3 123 0.82 49.25 8.42 94.08
197 INT6868 Gene_expression of GFAP 136 0.78 84.65 22.7 93.88
198 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 93.88
199 INT200738 Gene_expression of HIST2H4A 7 0.18 4.65 0.91 93.84
200 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 93.80
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