D:Androgen Insensitivity

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pChart

Disease Term
Synonyms Androgen Insensitivity Syndrome, ANDROGEN INSENSITIVITY SYNDROME COMPLETE, Androgen Insensitivity Syndrome Partial, Androgen Insensitivity Syndromes Partial, ANDROGEN RESISTANCE SYNDROME, REIFENSTEIN S SYNDROME, REIFENSTEIN SYNDROME, REIFENSTEINS SYNDROME, Testicular Feminization
Documents 25
Hot Single Events 19
Hot Interactions 3

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Androgen Insensitivity. They are ordered first by their relevance to Androgen Insensitivity and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT270758 GNRHR Positive_regulation of Localization of FSHR 1 0.08 0.68 0 92.40
2 INT44441 GNRH1 Positive_regulation of Localization of FSHR 2 0.15 0.86 0.26 91.12
3 INT279633 Binding of Ar and Abpe 1 0.01 0.99 0 81.36
4 INT279632 Positive_regulation of Binding of Ar and Nr4a1 1 0.01 0.86 0.03 64.72
5 INT279634 Binding of Ar and Nr4a1 1 0.01 0.85 0.03 64.32
6 INT241844 Positive_regulation of GNRH1 Positive_regulation of Localization of PLOD1 1 0.13 0.08 0.15 5.00
7 INT270759 Binding of HSD11B1 and TERT 1 0.07 1.67 0 5.00
8 INT279635 Ar Regulation of Abpe 1 0.01 1.55 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Androgen Insensitivity. They are ordered first by their pain relevance and then by number of times they were reported in Androgen Insensitivity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT3948 Regulation of Cck 291 0.62 58.07 255.88 98.12
2 INT5040 Regulation of Gal 42 0.60 12.72 21.18 98.12
3 INT99091 Regulation of AR 70 0.45 31.68 5.05 98.00
4 INT920 Localization of PLOD1 223 0.81 42.25 78.7 97.64
5 INT917 Positive_regulation of Localization of PLOD1 51 0.69 8.53 22.87 97.64
6 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61 97.60
7 INT943 Negative_regulation of Cck 205 0.59 38.42 174.78 96.78
8 INT1793 Localization of CGA 379 0.81 67.38 114.69 96.28
9 INT1794 Regulation of Localization of CGA 136 0.57 13.39 59.07 96.28
10 INT7035 Regulation of CGA 87 0.45 29.04 28.45 95.96
11 INT32962 Positive_regulation of Localization of GNRHR 3 0.41 0.59 0.49 93.48
12 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 92.92
13 INT15607 Localization of GNRHR 14 0.62 7.56 2.3 92.92
14 INT179300 Negative_regulation of TGFB1I1 1 0.06 1.92 0 91.92
15 INT912 Localization of FSHR 91 0.79 23.61 15.58 89.72
16 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92 82.32
17 INT9128 Regulation of Gene_expression of Cck 27 0.62 6.55 19.45 82.32
18 INT8650 Gene_expression of Gal 152 0.78 61.97 81.72 81.52
19 INT61706 Regulation of Gene_expression of Gal 17 0.62 10.09 11.96 81.52
20 INT18672 Gene_expression of Ncam1 54 0.78 36.64 18.79 75.00
21 INT243082 Binding of Ar 2 0.11 1.81 0.06 66.68
22 INT114279 Positive_regulation of Nr4a1 9 0.59 3.37 1.59 64.72
23 INT1792 Positive_regulation of CGA 123 0.70 64.73 20.79 63.52
24 INT35366 Binding of AR 87 0.47 30.52 8.9 60.40
25 INT117096 Gene_expression of Wnt4 2 0.67 4.68 0.38 59.04
26 INT99495 Gene_expression of SRD5A1 14 0.77 5 9.21 53.96
27 INT127273 Gene_expression of AMH 24 0.78 9.53 0.47 42.88
28 INT279630 Regulation of Abpe 1 0.13 1.07 0.09 31.00
29 INT182465 Negative_regulation of Cd1d1 4 0.28 1.72 0.29 25.92
30 INT216123 Negative_regulation of Cd68 2 0.41 1.96 1.48 21.76
31 INT265440 Gene_expression of Abpe 2 0.19 10.64 1.07 20.32
32 INT279631 Negative_regulation of Abpe 1 0.12 1.29 0.04 20.12
33 INT123520 Gene_expression of Ar 12 0.32 6.98 0.25 19.04
34 INT134296 Positive_regulation of Ptges2 20 0.19 14.85 3.8 6.36
35 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
36 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
37 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
38 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
39 INT251 Regulation of INS 398 0.62 232.47 55.04 5.00
40 INT5130 Regulation of GNRH1 139 0.62 31.95 42.08 5.00
41 INT3933 Positive_regulation of PLOD1 128 0.70 30.76 42.03 5.00
42 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
43 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 5.00
44 INT5868 Positive_regulation of GNRH1 122 0.69 20.96 32.8 5.00
45 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
46 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 5.00
47 INT7397 Negative_regulation of Localization of GNRH1 86 0.59 15.45 29.78 5.00
48 INT5135 Negative_regulation of GNRH1 106 0.58 36.63 27.71 5.00
49 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 5.00
50 INT1638 Negative_regulation of PLOD1 92 0.59 21.69 26.61 5.00
51 INT5131 Gene_expression of GNRH1 109 0.78 28.79 23.94 5.00
52 INT7113 Negative_regulation of Localization of CGA 71 0.51 17.7 23.42 5.00
53 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 5.00
54 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 5.00
55 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66 5.00
56 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 5.00
57 INT1642 Negative_regulation of Localization of PLOD1 40 0.58 10.67 17.95 5.00
58 INT7970 Gene_expression of PLOD1 120 0.71 44.42 15.54 5.00
59 INT26538 Positive_regulation of FSHR 103 0.69 30.95 15.33 5.00
60 INT4145 Gene_expression of FSHR 124 0.77 44.98 13.04 5.00
61 INT7234 Binding of GNRH1 43 0.47 21.59 12.36 5.00
62 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 5.00
63 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75 5.00
64 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 5.00
65 INT68960 Gene_expression of Ptger4 42 0.67 15.75 9.64 5.00
66 INT1647 Negative_regulation of FSHR 54 0.45 13.44 8.87 5.00
67 INT13435 Positive_regulation of RTCA 31 0.60 7.19 8.5 5.00
68 INT186142 Gene_expression of Ghrh 45 0.66 34.04 6.94 5.00
69 INT26585 Gene_expression of Vim 117 0.77 39.97 6 5.00
70 INT41892 Gene_expression of HBM 48 0.64 28.32 5.64 5.00
71 INT64888 Negative_regulation of HBM 52 0.16 34.33 5.45 5.00
72 INT8340 Negative_regulation of SHBG 49 0.57 35.96 4.73 5.00
73 INT4146 Binding of SHBG 49 0.47 31 4.71 5.00
74 INT78023 Gene_expression of DDX41 13 0.65 23.55 3.84 5.00
75 INT34720 Positive_regulation of SHBG 58 0.69 32.4 3.83 5.00
76 INT5204 Positive_regulation of Gene_expression of AR 60 0.67 23.54 3.53 5.00
77 INT545 Binding of GC 15 0.45 10.74 3.47 5.00
78 INT1646 Negative_regulation of Localization of FSHR 17 0.58 7.36 3.46 5.00
79 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04 5.00
80 INT15606 Localization of FSHB 24 0.78 9.16 2.49 5.00
81 INT15604 Gene_expression of FSHB 30 0.56 9.7 2.45 5.00
82 INT89971 Localization of Sparc 10 0.80 10.25 1.85 5.00
83 INT84722 Regulation of Gene_expression of AR 20 0.61 7.73 1.69 5.00
84 INT33496 Positive_regulation of Gene_expression of FSHR 14 0.46 6.05 1.66 5.00
85 INT245259 Localization of Mmp3 6 0.68 4.49 1.58 5.00
86 INT41986 Positive_regulation of Gene_expression of HSD11B1 26 0.49 32.84 1.52 5.00
87 INT160264 Localization of Fn1 10 0.40 3.95 1.51 5.00
88 INT147607 Binding of TERT 16 0.48 12.36 1.31 5.00
89 INT25032 Negative_regulation of Gene_expression of FSHR 11 0.39 1.99 1.2 5.00
90 INT25432 Negative_regulation of Gene_expression of GHRH 6 0.37 2.9 1.12 5.00
91 INT159988 Localization of Ctsk 5 0.70 2.9 0.74 5.00
92 INT85861 Localization of Abpe 6 0.21 1.33 0.66 5.00
93 INT163993 Gene_expression of Hnf1a 2 0.65 1.38 0.49 5.00
94 INT279626 Regulation of Gene_expression of Abpe 1 0.13 3.24 0.38 5.00
95 INT258074 Negative_regulation of HDLBP 2 0.06 2.76 0.28 5.00
96 INT97625 Negative_regulation of Regulation of GNRH1 2 0.39 0.89 0.27 5.00
97 INT170062 Negative_regulation of Gene_expression of HBM 3 0.16 4.82 0.25 5.00
98 INT279628 Negative_regulation of Ar 5 0.04 6.1 0.25 5.00
99 INT279627 Transcription of Abpe 1 0.20 1.38 0.2 5.00
100 INT216124 Negative_regulation of Pcna 3 0.13 2.06 0.19 5.00
101 INT185673 Negative_regulation of Negative_regulation of AR 3 0.28 1.12 0.12 5.00
102 INT279629 Positive_regulation of Abpe 1 0.20 2.22 0.12 5.00
103 INT243079 Regulation of Ar 3 0.08 1.22 0.12 5.00
104 INT162428 Localization of Ar 4 0.37 2.4 0.07 5.00
105 INT213363 Regulation of Gene_expression of Ar 2 0.11 1.63 0.03 5.00
106 INT279625 Positive_regulation of Gene_expression of Abpe 1 0.14 0.76 0 5.00
107 INT205576 Positive_regulation of Hnf1a 2 0.49 1.1 0 5.00
108 INT205587 Negative_regulation of Cyp17a1 1 0.28 0.24 0 5.00
109 INT205583 Gene_expression of Hnf1b 1 0.59 2.09 0 5.00
110 INT241848 Protein_catabolism of CNDP2 1 0.02 0.81 0 5.00
111 INT205579 Positive_regulation of Gene_expression of Hnf1b 1 0.44 2.1 0 5.00
112 INT205582 Positive_regulation of Hnf1b 1 0.44 1.05 0 5.00
113 INT205585 Regulation of Wnt4 1 0.45 0.7 0 5.00
114 INT205578 Negative_regulation of Wnt4 1 0.43 1.69 0 5.00
115 INT241849 Positive_regulation of Protein_catabolism of CNDP2 1 0.01 0.82 0 5.00
116 INT279624 Negative_regulation of Gpx3 2 0.18 0.67 0 5.00
117 INT205581 Regulation of Negative_regulation of Wnt4 1 0.27 0.7 0 5.00
118 INT205577 Positive_regulation of Gene_expression of Hnf1a 1 0.49 1.1 0 5.00
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