D:Angiomyolipoma

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms ANGIOMYOLIPOMAS, Benign Kidney Tumor, Benign Kidney Tumors, Benign Kidney Tumour, BENIGN KIDNEY TUMOURS
Documents 196
Hot Single Events 24
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Angiomyolipoma. They are ordered first by their relevance to Angiomyolipoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT272012 Binding of TSC1 and Lsamp 1 0.03 2.1 0.08 56.48
2 INT272018 Binding of TSC1 and Tsc2 1 0.17 0.48 0 37.64
3 INT272006 Binding of YWHAQ and Tsc2 1 0.27 0.39 0.1 5.00
4 INT272003 Binding of Tsc2 and Tsc1 1 0.18 1.1 0.07 5.00
5 INT272009 Binding of YWHAQ and Tsc1 1 0.37 0.14 0.03 5.00
6 INT271990 Tsc1 Positive_regulation of Tsc2 1 0.36 0.31 0 5.00
7 INT271996 Binding of Plk1 and Tsc1 1 0.09 0.32 0 5.00
8 INT271991 Tsc1 Regulation of Tsc2 1 0.23 0.15 0 5.00
9 INT272015 Pkd1 Positive_regulation of Localization of TSC1 1 0.18 0.65 0 5.00
10 INT272017 TBC1D7 Positive_regulation of Protein_catabolism of Tsc1 1 0.08 0.46 0 5.00
11 INT271982 Binding of Skp2 and Psmd9 1 0.01 0.68 0 5.00
12 INT272013 Binding of OGG1 and Tsc2 1 0.09 0.67 0 5.00
13 INT272010 Tsc2 Negative_regulation of OGG1 1 0.17 0.6 0 5.00
14 INT271966 Phosphorylation of Rasa1 Positive_regulation of Tsc2 1 0.01 0.31 0 5.00
15 INT272000 Binding of Skp2 and Hecw1 1 0.01 0.11 0 5.00
16 INT271985 Tsc1 Regulation of Cdkn1b 1 0.04 0.1 0 5.00
17 INT271979 Skp2 Positive_regulation of Protein_catabolism of Psmd9 1 0.01 0.35 0 5.00
18 INT272008 Tsc1 Negative_regulation of Binding of HERC1 1 0.01 0.32 0 5.00
19 INT272014 Binding of RB1CC1 and Tsc1 1 0.05 0.44 0 5.00
20 INT272016 Mtor Negative_regulation of INS 1 0.00 0.61 0 5.00
21 INT271997 Binding of Cdk1 and Plk1 1 0.03 0.3 0 5.00
22 INT271999 Binding of Fkbp1a and Positive_regulation of Negative_regulation of Mtor 1 0.00 0.18 0 5.00
23 INT271984 Binding of Tsc2 and Skp2 1 0.06 0.34 0 5.00
24 INT272011 Binding of RAB5A and Tsc2 1 0.02 0.16 0 5.00
25 INT272004 Binding of Hspa1b and Tsc2 1 0.01 0.45 0 5.00
26 INT271983 Binding of Tsc2 and Rap1a 1 0.02 0.16 0 5.00
27 INT271994 Binding of Fkbp1a and Mtor 1 0.00 0.22 0 5.00
28 INT272005 Phosphorylation of Tsc1 Regulation of Binding of Cdk1 and Plk1 1 0.02 0.3 0 5.00
29 INT271989 Binding of Tsc2 and Psmd9 1 0.02 0.47 0 5.00
30 INT272007 Binding of Tsc2 and SCPEP1 1 0.27 0.46 0 5.00
31 INT271998 Cdk1 Positive_regulation of Phosphorylation of Tsc1 1 0.17 0.3 0 5.00
32 INT271978 Positive_regulation of Racgap1 Regulation of Mtor 1 0.00 0.54 0 5.00
33 INT271987 Tsc2 Regulation of Skp2 1 0.10 0.28 0 5.00
34 INT271986 Tsc1 Regulation of Skp2 1 0.13 0.14 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Angiomyolipoma. They are ordered first by their pain relevance and then by number of times they were reported in Angiomyolipoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT170333 Binding of IFN1@ 68 0.47 49.01 9.72 99.04
2 INT89445 Gene_expression of MEPE 17 0.58 18.07 1.55 98.48
3 INT6868 Gene_expression of GFAP 136 0.78 84.65 22.7 96.76
4 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 96.52
5 INT119227 Gene_expression of Tsc2 8 0.68 10.67 0.03 93.84
6 INT246761 Positive_regulation of Gene_expression of Tsc2 2 0.41 1.17 0 93.84
7 INT182417 Positive_regulation of OGG1 2 0.44 0.83 0 92.00
8 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 89.28
9 INT59784 Binding of DES 22 0.47 19.48 2.27 88.76
10 INT188795 Positive_regulation of SRMS 3 0.69 3.02 0.2 88.56
11 INT259266 Negative_regulation of Positive_regulation of SRMS 1 0.37 1.58 0.16 88.56
12 INT259267 Negative_regulation of Gene_expression of ZNF135 1 0.26 1.52 0.16 87.56
13 INT214073 Binding of TSC1 9 0.37 22 1.34 87.44
14 INT259268 Gene_expression of ZNF135 1 0.41 1.52 0.15 87.16
15 INT188741 Binding of ACTG2 3 0.20 3.27 0 86.24
16 INT175423 Positive_regulation of TSC1 25 0.36 21.81 0.45 84.28
17 INT184803 Localization of TSC1 5 0.37 6.13 0.32 82.88
18 INT4991 Positive_regulation of Vim 74 0.69 69.84 8.33 82.32
19 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 81.20
20 INT127607 Gene_expression of EID1 4 0.63 5.57 1.6 80.76
21 INT120693 Positive_regulation of MEPE 7 0.50 8.22 0.79 80.76
22 INT143908 Positive_regulation of EID1 2 0.17 2.27 0.09 80.76
23 INT182413 Binding of OGG1 17 0.46 2.44 0.22 80.36
24 INT271960 Positive_regulation of Binding of TSC1 1 0.25 0.88 0.03 80.24
25 INT302534 Localization of Mest 1 0.28 1.81 0 78.96
26 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 78.20
27 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63 71.00
28 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19 70.68
29 INT121493 Gene_expression of XRCC1 55 0.65 73.43 2.76 69.36
30 INT206929 Negative_regulation of Gene_expression of XRCC1 4 0.25 6.14 0.74 69.36
31 INT127654 Positive_regulation of Gene_expression of XRCC1 11 0.38 13.7 0.26 69.36
32 INT156827 Localization of MRI1 25 0.65 16.06 8.33 68.36
33 INT170754 Localization of IFN1@ 121 0.78 66.78 15.6 68.00
34 INT15652 Positive_regulation of ENO2 37 0.68 33.39 5.02 63.92
35 INT18898 Positive_regulation of CHGA 38 0.67 28.99 4.86 63.92
36 INT16277 Regulation of CHGA 16 0.44 11.31 4.43 63.92
37 INT11920 Regulation of ENO2 18 0.55 11.51 2.89 63.92
38 INT214458 Binding of ALK 1 0.17 1.84 0.46 63.36
39 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 60.64
40 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 58.96
41 INT151450 Positive_regulation of Gene_expression of Kit 23 0.69 13.11 1.43 58.96
42 INT271914 Negative_regulation of Tsc1 5 0.38 3.08 0.04 58.84
43 INT271930 Gene_expression of Tsc1 1 0.69 6.88 0.04 58.04
44 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 57.80
45 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 55.36
46 INT34354 Gene_expression of SRMS 8 0.59 9.62 1.02 51.76
47 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 49.72
48 INT246774 Positive_regulation of Tsc2 6 0.41 2.4 0 46.64
49 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 46.32
50 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 45.92
51 INT271915 Negative_regulation of Pkd1 8 0.36 6.44 0 37.60
52 INT74019 Regulation of TSC1 27 0.35 23.61 0.79 35.76
53 INT151774 Positive_regulation of Mtor 38 0.45 20.15 1.01 31.48
54 INT55470 Regulation of Mtor 16 0.24 12.51 2.07 30.36
55 INT271917 Phosphorylation of Mtor 11 0.13 6.76 0.78 29.12
56 INT95636 Gene_expression of ACTG2 23 0.44 19.87 1.75 28.28
57 INT246776 Negative_regulation of Tsc2 18 0.48 6.82 0.12 27.80
58 INT271931 Negative_regulation of Gene_expression of Tsc1 1 0.38 0.44 0 27.80
59 INT259270 Negative_regulation of SRMS 1 0.38 1.04 0.04 26.56
60 INT322756 Negative_regulation of Tsc1 1 0.07 1.4 0.26 23.60
61 INT97779 Negative_regulation of TSC2 3 0.41 3.45 0.26 23.24
62 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 17.68
63 INT205040 Gene_expression of CLTA 7 0.19 7.64 0.25 15.08
64 INT192533 Positive_regulation of CLTA 4 0.13 4.98 0.1 15.08
65 INT239514 Positive_regulation of Gene_expression of CLTA 1 0.14 1.69 0.05 15.08
66 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19 14.96
67 INT36798 Gene_expression of Mki67 178 0.77 132 8.24 11.32
68 INT26585 Gene_expression of Vim 117 0.77 39.97 6 11.32
69 INT160853 Gene_expression of Syp 87 0.72 20.06 5.31 11.32
70 INT133905 Gene_expression of Ncam1 24 0.78 10.2 4.62 11.32
71 INT132903 Gene_expression of Cd34 65 0.72 33.95 2.2 11.32
72 INT248470 Gene_expression of Ighmbp2 5 0.75 3.32 0.68 11.32
73 INT271927 Positive_regulation of Tsc1 1 0.44 0.4 0 11.12
74 INT271919 Gene_expression of Tsc2 6 0.39 2.23 0 9.64
75 INT259264 Localization of ZNF135 1 0.46 1.52 0 8.16
76 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
77 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
78 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
79 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 5.00
80 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 5.00
81 INT170444 Binding of Gopc 172 0.39 45.05 20.71 5.00
82 INT12725 Positive_regulation of Racgap1 66 0.68 32.74 19.29 5.00
83 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 5.00
84 INT180497 Binding of MRI1 45 0.42 28.35 14.77 5.00
85 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 5.00
86 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 5.00
87 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 5.00
88 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 5.00
89 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 5.00
90 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49 5.00
91 INT92916 Gene_expression of Acta2 50 0.74 17.52 6.11 5.00
92 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21 5.00
93 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12 5.00
94 INT111477 Gene_expression of KRT7 90 0.74 86.76 4.07 5.00
95 INT123411 Gene_expression of Sp1 15 0.69 4.2 3.79 5.00
96 INT22237 Localization of NTS 14 0.75 5.5 2.77 5.00
97 INT97973 Positive_regulation of XRCC1 24 0.40 30.95 2.26 5.00
98 INT151449 Negative_regulation of Gene_expression of Kit 18 0.45 12.05 2.23 5.00
99 INT83896 Gene_expression of CD1A 19 0.68 15.58 2.1 5.00
100 INT37216 Binding of SMN1 11 0.36 6.66 1.86 5.00
101 INT113147 Positive_regulation of Acta2 6 0.34 4.24 1.66 5.00
102 INT50568 Positive_regulation of HCA1 5 0.44 5.56 1.63 5.00
103 INT64233 Regulation of Trp53 35 0.62 27.11 1.53 5.00
104 INT93274 Gene_expression of QRFP 12 0.58 7 1.46 5.00
105 INT167283 Negative_regulation of Phosphorylation of Gsk3b 12 0.59 7.94 1.16 5.00
106 INT74020 Negative_regulation of XRCC1 16 0.35 17.18 1.06 5.00
107 INT34355 Binding of SRMS 7 0.41 3.69 1.06 5.00
108 INT74021 Regulation of XRCC1 15 0.44 16.91 0.88 5.00
109 INT126523 Phosphorylation of Mapkapk2 19 0.79 7.76 0.82 5.00
110 INT129174 Gene_expression of PKD1 24 0.67 14.91 0.74 5.00
111 INT184694 Gene_expression of Usf1 10 0.55 4.27 0.72 5.00
112 INT200219 Positive_regulation of VHL 18 0.50 15.38 0.67 5.00
113 INT71497 Binding of Hspa1b 3 0.08 1.43 0.58 5.00
114 INT182435 Localization of OGG1 36 0.76 1.66 0.58 5.00
115 INT36201 Gene_expression of ETFA 8 0.66 9.18 0.58 5.00
116 INT194903 Binding of Cd34 12 0.37 5.06 0.56 5.00
117 INT84526 Binding of QRFP 3 0.07 1.45 0.48 5.00
118 INT271939 Regulation of Tsc1 2 0.41 1.16 0.47 5.00
119 INT247798 Negative_regulation of Rasa1 3 0.09 1.05 0.44 5.00
120 INT230653 Phosphorylation of Rasa1 3 0.55 0.6 0.42 5.00
121 INT271922 Phosphorylation of Cdk1 2 0.44 0.37 0.39 5.00
122 INT173086 Negative_regulation of VHL 14 0.59 12.54 0.29 5.00
123 INT126522 Positive_regulation of Phosphorylation of Mapkapk2 7 0.59 3.8 0.28 5.00
124 INT190676 Binding of Fkbp1a 15 0.36 3.11 0.28 5.00
125 INT70144 Gene_expression of Sry 4 0.63 1.15 0.28 5.00
126 INT241240 Gene_expression of Pkd1 18 0.54 12.2 0.27 5.00
127 INT246762 Phosphorylation of Tsc2 60 0.67 15.71 0.25 5.00
128 INT166125 Gene_expression of PHOSPHO1 4 0.75 3.06 0.24 5.00
129 INT271929 Protein_catabolism of Psmd9 4 0.11 1.69 0.21 5.00
130 INT218159 Regulation of SRMS 3 0.39 1.69 0.2 5.00
131 INT179044 Regulation of Cdkn1b 4 0.22 2.64 0.18 5.00
132 INT228901 Positive_regulation of RPS6KB1 5 0.55 2.44 0.18 5.00
133 INT239446 Binding of Lpn1 1 0.01 0.81 0.16 5.00
134 INT271943 Phosphorylation of Tsc2 9 0.52 3.35 0.13 5.00
135 INT271573 Binding of SCPEP1 3 0.35 1.21 0.13 5.00
136 INT246749 Negative_regulation of Phosphorylation of Tsc2 11 0.35 3.4 0.12 5.00
137 INT271941 Binding of Tsc2 12 0.24 2.96 0.11 5.00
138 INT257438 Phosphorylation of SRMS 3 0.80 1.4 0.11 5.00
139 INT228902 Gene_expression of RPS6KB1 5 0.75 2.32 0.1 5.00
140 INT113319 Positive_regulation of QRFP 5 0.40 3.86 0.1 5.00
141 INT121495 Transcription of XRCC1 7 0.49 6.11 0.09 5.00
142 INT271938 Binding of Tsc1 1 0.43 3.18 0.07 5.00
143 INT259265 Regulation of Phosphorylation of SRMS 1 0.39 1.08 0.07 5.00
144 INT239516 Negative_regulation of Gene_expression of QRFP 1 0.09 0.26 0.06 5.00
145 INT211006 Binding of PKD1 6 0.22 2.69 0.05 5.00
146 INT197280 Regulation of Psmd9 2 0.07 0.1 0.05 5.00
147 INT302533 Gene_expression of Mest 2 0.65 1.86 0.05 5.00
148 INT239512 Negative_regulation of Gene_expression of CLTA 1 0.12 0.47 0.04 5.00
149 INT239515 Localization of QRFP 1 0.15 0.45 0.04 5.00
150 INT271916 Positive_regulation of Phosphorylation of Tsc2 4 0.32 0.52 0.04 5.00
151 INT257437 Localization of SRMS 2 0.65 1.11 0.04 5.00
152 INT239517 Negative_regulation of Localization of QRFP 1 0.09 0.46 0.04 5.00
153 INT271937 Positive_regulation of Binding of Tsc2 1 0.25 0 0.04 5.00
154 INT302535 Gene_expression of NLRP2 3 0.65 2.14 0.03 5.00
155 INT249790 Protein_catabolism of Skp2 2 0.58 1.02 0.03 5.00
156 INT239513 Positive_regulation of Gene_expression of QRFP 1 0.10 0.54 0.03 5.00
157 INT271964 Binding of HERC1 1 0.01 0.31 0 5.00
158 INT228904 Positive_regulation of PHOSPHO1 1 0.45 0.84 0 5.00
159 INT271935 Positive_regulation of Phosphorylation of Rps6 1 0.02 0.17 0 5.00
160 INT271924 Positive_regulation of Protein_catabolism of Psmd9 1 0.05 0.35 0 5.00
161 INT271905 Positive_regulation of Protein_catabolism of Tsc2 1 0.35 1.46 0 5.00
162 INT271965 Negative_regulation of Binding of TSC1 1 0.33 0.44 0 5.00
163 INT271921 Negative_regulation of Tsc2 2 0.26 1.19 0 5.00
164 INT271928 Binding of Plk1 1 0.07 0.29 0 5.00
165 INT271904 Localization of Tsc2 1 0.41 1.31 0 5.00
166 INT228895 Binding of Tsc2 5 0.30 2.41 0 5.00
167 INT228899 Positive_regulation of Gene_expression of PHOSPHO1 1 0.49 0.84 0 5.00
168 INT271936 Phosphorylation of Tsc1 4 0.73 1.76 0 5.00
169 INT246755 Regulation of Tsc2 4 0.50 1.01 0 5.00
170 INT161700 Positive_regulation of Psmd9 3 0.59 0.41 0 5.00
171 INT271962 Localization of SLC7A6 1 0.73 0.08 0 5.00
172 INT242456 Binding of Cdk2 2 0.16 1.29 0 5.00
173 INT271913 Protein_catabolism of Tsc1 1 0.51 0.45 0 5.00
174 INT271940 Protein_catabolism of Tsc2 1 0.50 0.7 0 5.00
175 INT228900 Positive_regulation of Gene_expression of RPS6KB1 2 0.49 1.6 0 5.00
176 INT271906 Negative_regulation of Binding of Tsc1 1 0.38 0.06 0 5.00
177 INT214045 Negative_regulation of OGG1 5 0.36 3.49 0 5.00
178 INT271944 Negative_regulation of Phosphorylation of Tsc2 2 0.30 0.42 0 5.00
179 INT271903 Positive_regulation of Protein_catabolism of Skp2 1 0.14 0.47 0 5.00
180 INT322758 Positive_regulation of Localization of TSC1 1 0.06 1.4 0 5.00
181 INT271910 Gene_expression of Hsf2 4 0.45 1.63 0 5.00
182 INT271920 Negative_regulation of Protein_catabolism of Skp2 1 0.12 0.37 0 5.00
183 INT271934 Binding of Psmd9 1 0.03 0.66 0 5.00
184 INT259269 Positive_regulation of Binding of SRMS 1 0.44 1.05 0 5.00
185 INT271923 Regulation of Binding of Plk1 1 0.09 0.29 0 5.00
186 INT271963 Phosphorylation of TSC1 2 0.31 2.02 0 5.00
187 INT271907 Phosphorylation of Rps6 4 0.09 0.67 0 5.00
188 INT228903 Negative_regulation of Gene_expression of PHOSPHO1 1 0.42 0.79 0 5.00
189 INT271926 Negative_regulation of Protein_catabolism of Psmd9 1 0.04 0.37 0 5.00
190 INT271961 Phosphorylation of PRKD1 1 0.02 0.6 0 5.00
191 INT271909 Positive_regulation of Tsc2 1 0.25 0.06 0 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox