D:Anorexia

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Disease Term
Synonyms ANOREXIAS, Anorexic, APPETITE ABSENT, Appetite Impaired, Appetite Loss, Appetite Lost, Inappetence, LACK OF APPETITE, Loss Of Appetite, No Appetite, Off Food
Documents 862
Hot Single Events 200
Hot Interactions 18

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Anorexia. They are ordered first by their relevance to Anorexia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT175560 Binding of GPER and GHRL 1 0.01 1.14 0.03 100.00
2 INT214144 Cck Positive_regulation of Pomc 1 0.15 0.94 2.39 99.84
3 INT214159 Cck Positive_regulation of Nts 1 0.03 0.93 2.34 99.84
4 INT214162 Gabrg1 Negative_regulation of Pomc 1 0.05 0.65 0.46 99.48
5 INT128943 Pomc Regulation of Npy 1 0.23 0.61 0.81 99.08
6 INT214164 Binding of Mc4r and Pomc 1 0.39 1.31 0.53 97.72
7 INT214160 Binding of Lep and Mc4r 1 0.29 1.31 0.53 97.72
8 INT214143 Binding of Lep and Pomc 1 0.27 1.2 0.53 96.96
9 INT284916 IL1RN Negative_regulation of HDAC4 1 0.00 1.66 0.03 96.92
10 INT204087 IL1B Positive_regulation of Gene_expression of LEP 1 0.09 2.6 0.54 96.00
11 INT214146 Msx1 Positive_regulation of Gene_expression of Nucb2 1 0.05 0.19 0.05 95.20
12 INT214163 Binding of Lep and Nts 1 0.04 0.21 0.74 91.60
13 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66 86.12
14 INT214153 Lep Regulation of Transcription of Nucb2 1 0.35 0.15 0.06 85.60
15 INT214169 Localization of PYY3 Positive_regulation of Localization of Pomc 1 0.13 0.29 0.08 84.92
16 INT297613 Negative_regulation of ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.66 0 84.84
17 INT297614 ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.56 0 81.24
18 INT214157 Positive_regulation of Mc3r Regulation of Npy 1 0.14 0.49 0.33 80.96
19 INT214151 Gabrg1 Negative_regulation of Gene_expression of Agrp 1 0.04 0.52 0.4 79.00
20 INT214147 Gabrg1 Negative_regulation of Gene_expression of Npy 1 0.03 0.52 0.4 79.00
21 INT352961 Ghrl Positive_regulation of Localization of GHSR 1 0.18 1.19 0.21 76.56
22 INT132318 Ghrl Positive_regulation of Localization of GH1 5 0.32 4.49 0.84 74.64
23 INT175561 NAA50 Negative_regulation of PRELID1 1 0.00 0.83 0.1 63.00
24 INT214145 Binding of Agrp and Mc4r 1 0.40 0.18 0.37 60.24
25 INT214158 Binding of Agrp and Mc3r 1 0.35 0.18 0.37 59.52
26 INT299015 Binding of FAS and Il18 1 0.38 0.83 0.11 57.60
27 INT214140 Agrp Positive_regulation of Mc3r 1 0.34 0.23 0.37 54.96
28 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 54.40
29 INT214142 Agrp Positive_regulation of Mc4r 1 0.39 0.23 0.37 54.24
30 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25 49.16
31 INT308854 Bcl2a1a Positive_regulation of Gene_expression of HTT 1 0.14 0 0 44.32
32 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48 43.00
33 INT245329 ATR Negative_regulation of DCD 1 0.10 0.91 0.05 39.12
34 INT245331 ATR Regulation of IL1B 1 0.03 0.91 0.05 39.12
35 INT245330 ATR Regulation of TNF 1 0.04 0.9 0.05 39.12
36 INT218733 Trh Positive_regulation of Gene_expression of Hdc 1 0.27 0 0.09 34.08
37 INT262335 Binding of Sv2a and Bri3 1 0.01 0.71 0.08 27.16
38 INT29521 Ace Positive_regulation of ACE 1 0.19 0 0.04 25.00
39 INT242102 Nkx2-1 Regulation of Gene_expression of Ttf1 1 0.00 1.55 0 21.16
40 INT214139 Lep Regulation of Localization of Pomc 1 0.20 0.4 0 10.52
41 INT214155 Lep Regulation of Gene_expression of Pomc 1 0.20 0.4 0 10.52
42 INT214141 Binding of Lep and Lepr 1 0.32 0.82 0.12 7.52
43 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3 5.00
44 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75 5.00
45 INT194513 Timp1 Negative_regulation of Cpox 1 0.00 0.9 1.31 5.00
46 INT262336 Binding of Abat and Tmem132a 1 0.00 1.39 1.14 5.00
47 INT332776 FSCN1 Positive_regulation of Grin1 1 0.02 0.21 1.12 5.00
48 INT81127 Binding of Gabrd and Abat 3 0.25 0 0.96 5.00
49 INT186672 IL8 Positive_regulation of Transcription of PTH 1 0.01 1.83 0.85 5.00
50 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 5.00
51 INT186674 Binding of BGLAP and CYP27A1 1 0.01 1.91 0.71 5.00
52 INT299004 Binding of Il18 and Il1 1 0.04 1.16 0.58 5.00
53 INT172207 Binding of Drd4 and ADHD1 2 0.03 1.56 0.48 5.00
54 INT352387 Binding of CFP and HPSE 1 0.01 1.25 0.46 5.00
55 INT298999 Binding of Il18bp and Il18 1 0.02 0 0.45 5.00
56 INT179432 Binding of pcp and AICDA 1 0.03 3.51 0.43 5.00
57 INT186673 IL8 Positive_regulation of Positive_regulation of PTH 1 0.01 0.92 0.42 5.00
58 INT291449 Car2 Positive_regulation of SK 1 0.03 0 0.39 5.00
59 INT187361 Binding of Gabrg1 and Kcnn3 1 0.36 0.13 0.3 5.00
60 INT298996 Il18 Positive_regulation of Gene_expression of Cdk5r1 1 0.03 1.65 0.29 5.00
61 INT298995 Il18 Positive_regulation of Gene_expression of Cdk5 1 0.12 1.65 0.29 5.00
62 INT299008 Il18 Positive_regulation of Transcription of Cdk5 1 0.12 1.65 0.29 5.00
63 INT299011 Il18 Positive_regulation of Transcription of Cdk5r1 1 0.03 1.65 0.29 5.00
64 INT224458 TNF Positive_regulation of Gene_expression of Nfkb1 2 0.34 1.47 0.26 5.00
65 INT262354 TRIP10 Negative_regulation of Cyp4a3 1 0.00 0.8 0.26 5.00
66 INT291446 Bdnf Positive_regulation of Positive_regulation of Ltp 1 0.02 0 0.26 5.00
67 INT262353 TRIP10 Negative_regulation of Cyp1a2 1 0.03 0.8 0.26 5.00
68 INT262329 TRIP10 Negative_regulation of CYP2C19 1 0.01 0.8 0.26 5.00
69 INT262330 Positive_regulation of TRIP10 Negative_regulation of CYP2C19 1 0.01 0.8 0.26 5.00
70 INT218732 Lep Regulation of Gene_expression of Trh 1 0.19 0.18 0.25 5.00
71 INT299013 Il18 Regulation of Ltp 1 0.05 0.39 0.25 5.00
72 INT298993 Il2 Positive_regulation of Gene_expression of Il13 1 0.01 0.73 0.24 5.00
73 INT299003 Il18 Positive_regulation of Gene_expression of Il13 1 0.11 0.73 0.24 5.00
74 INT291448 Prkaca Regulation of Gene_expression of Kcnn2 1 0.04 0 0.23 5.00
75 INT291447 Bdnf Positive_regulation of Prkaca 1 0.04 0 0.23 5.00
76 INT299000 Positive_regulation of Il18 Regulation of Ltp 1 0.05 0.35 0.2 5.00
77 INT182634 Binding of CCR5 and MIP 2 0.39 1.29 0.2 5.00
78 INT300562 Binding of Slc6a3 and Datd 1 0.02 1.12 0.2 5.00
79 INT300563 Binding of Drd5 and ADHD1 1 0.01 1.13 0.19 5.00
80 INT214170 Binding of DST and Lep 1 0.02 0.17 0.18 5.00
81 INT298998 Il18 Positive_regulation of Cdk5 1 0.11 0.36 0.17 5.00
82 INT299001 Il18 Positive_regulation of Cdk5r1 1 0.03 0.36 0.17 5.00
83 INT245332 ATR Regulation of IL6 1 0.03 0.35 0.17 5.00
84 INT243524 Positive_regulation of Binding of NTF3 and SOX10 1 0.01 0.54 0.14 5.00
85 INT299012 Binding of Il18bp and Il1f5 1 0.00 0 0.14 5.00
86 INT243525 Binding of NTF3 and SOX10 1 0.01 0.54 0.14 5.00
87 INT245333 ATR Negative_regulation of Protein_catabolism of DCD 1 0.10 0.93 0.14 5.00
88 INT214150 Binding of Mc3r and Msx1 1 0.03 0.5 0.12 5.00
89 INT214152 Binding of Mc4r and Msx1 1 0.03 0.24 0.11 5.00
90 INT236467 MMP9 Negative_regulation of SNRPB 1 0.01 0.45 0.1 5.00
91 INT204086 TNF Positive_regulation of Gene_expression of LEP 1 0.48 0.74 0.1 5.00
92 INT298994 Binding of Il18 and Il1f5 1 0.01 0 0.1 5.00
93 INT214165 Agrp Negative_regulation of Localization of Npy 1 0.23 0.06 0.1 5.00
94 INT214172 Son Regulation of Binding of Cck and Son 1 0.00 0.1 0.09 5.00
95 INT214138 Son Regulation of Gene_expression of Pomc 1 0.05 0.1 0.09 5.00
96 INT182644 Binding of CXCR4 and Cxcr4 1 0.10 0.66 0.09 5.00
97 INT214168 Msx1 Positive_regulation of Gene_expression of DST 1 0.00 0.13 0.09 5.00
98 INT214161 Pomc Regulation of Mc4r 1 0.21 0.1 0.09 5.00
99 INT214166 DST Negative_regulation of Gene_expression of Npy 1 0.02 0.07 0.09 5.00
100 INT214154 Binding of Cck and Son 1 0.02 0.1 0.09 5.00
101 INT214156 Pomc Negative_regulation of Gene_expression of Npy 1 0.39 0.07 0.09 5.00
102 INT270201 Binding of CD28 and Cd86 1 0.10 0.58 0.08 5.00
103 INT270203 Binding of CD28 and Apc 1 0.04 0.58 0.08 5.00
104 INT299002 Negative_regulation of Binding of Il18bp and Il18 1 0.02 0 0.08 5.00
105 INT291450 Kcnn3 Negative_regulation of Gene_expression of SK 1 0.10 0.53 0.08 5.00
106 INT224985 Binding of Ube3a and Snord116 1 0.34 0.45 0.08 5.00
107 INT270197 Binding of Apc and Cd86 1 0.02 0.58 0.08 5.00
108 INT270202 Binding of CD28 and Cd80 1 0.09 0.58 0.08 5.00
109 INT270198 Binding of Apc and Cd80 1 0.02 0.58 0.08 5.00
110 INT267776 Binding of Vdac3 and IgG 1 0.01 0.69 0.08 5.00
111 INT268679 Binding of HDAC1 and NCOR2 3 0.17 2.8 0.07 5.00
112 INT299009 Il1f5 Negative_regulation of Il18 1 0.01 0 0.07 5.00
113 INT172346 Gopc Regulation of Agrp 1 0.15 0.27 0.06 5.00
114 INT74033 Binding of IGHG3 and Ighg1 2 0.08 0.87 0.06 5.00
115 INT270199 Icos Positive_regulation of Localization of Il10 1 0.03 0.63 0.06 5.00
116 INT267781 Mvp Positive_regulation of Gopc 1 0.18 0.19 0.06 5.00
117 INT218734 Negative_regulation of Maob Positive_regulation of Positive_regulation of Ap3d1 1 0.00 0 0.05 5.00
118 INT172349 Eri1 Regulation of Gene_expression of Agrp 1 0.03 0.28 0.05 5.00
119 INT291451 Binding of CALM1 and Car2 1 0.00 0 0.05 5.00
120 INT236466 SNRPB Positive_regulation of NFKB2 1 0.00 0.21 0.05 5.00
121 INT267780 Binding of Mvp and Positive_regulation of Hand1 1 0.16 0.48 0.05 5.00
122 INT172348 Eri1 Negative_regulation of Gene_expression of Agrp 1 0.07 0.28 0.05 5.00
123 INT343498 Binding of ITIH4 and TPPP 1 0.06 0.64 0.05 5.00
124 INT224988 Binding of Snord116 and Snurf 1 0.15 0.22 0.04 5.00
125 INT224991 Snord116 Positive_regulation of SNORD108 1 0.37 0.61 0.04 5.00
126 INT326625 Binding of ALB and Trf 1 0.01 0.64 0.04 5.00
127 INT224986 Binding of Snrpn and Snord116 1 0.30 0.21 0.04 5.00
128 INT224990 Snord116 Positive_regulation of SNORD107 1 0.38 0.62 0.04 5.00
129 INT224987 Snord116 Positive_regulation of Snord64 1 0.55 0.62 0.04 5.00
130 INT270206 Hdl1 Positive_regulation of Gene_expression of IL2 1 0.01 0.35 0.03 5.00
131 INT214149 Binding of Lepr and Pomc 1 0.33 0.21 0.03 5.00
132 INT214167 Binding of DST and Pomc 1 0.03 0.22 0.03 5.00
133 INT214171 Binding of DST and Cartpt 1 0.01 0.21 0.03 5.00
134 INT214148 Binding of Lepr and Cartpt 1 0.09 0.21 0.03 5.00
135 INT213160 AGT Positive_regulation of Gene_expression of LEP 1 0.08 1.29 0.03 5.00
136 INT299006 Binding of Il18 and Myd88 1 0.21 0.19 0.03 5.00
137 INT261035 Hspg2 Positive_regulation of Gmcl1 1 0.01 0.4 0 5.00
138 INT354097 Timp1 Negative_regulation of Localization of NFKB2 1 0.04 0.94 0 5.00
139 INT267777 Positive_regulation of Binding of Mvp and IgG 1 0.12 0.89 0 5.00
140 INT172347 Eri1 Negative_regulation of Hras1 1 0.00 0.76 0 5.00
141 INT320959 Binding of HRAS and HMHA1 1 0.00 0.37 0 5.00
142 INT325904 Binding of F2 and Wbp5 1 0.01 1.22 0 5.00
143 INT210707 Binding of IFNA2 and IL2 1 0.06 0.91 0 5.00
144 INT261036 Adm Regulation of Gmcl1 1 0.04 0.4 0 5.00
145 INT325898 Negative_regulation of Binding of F2 and Gopc 1 0.03 0.14 0 5.00
146 INT278837 Binding of ALB and KAL1 1 0.03 0.16 0 5.00
147 INT325910 Wbp5 Positive_regulation of Positive_regulation of F2 1 0.01 0.67 0 5.00
148 INT343501 CD4 Regulation of ERVW-1 1 0.09 0.16 0 5.00
149 INT284919 XRCC6 Negative_regulation of BAX 1 0.01 0.64 0 5.00
150 INT349050 Binding of EPCAM and ZNF845 1 0.02 1.54 0 5.00
151 INT284920 Binding of HDAC1 and NCOR1 1 0.03 0.13 0 5.00
152 INT325900 Binding of Dio1 and Wbp5 1 0.00 0.25 0 5.00
153 INT284918 RUNX1T1 Regulation of DNMT1 1 0.21 1.09 0 5.00
154 INT325902 Binding of F2 and Fgg 1 0.01 0 0 5.00
155 INT284917 RUNX1T1 Regulation of HDAC9 1 0.19 1.09 0 5.00
156 INT272977 Osr1 Regulation of ADHD1 1 0.01 1.79 0 5.00
157 INT284914 Binding of HDAC1 and NCK1 1 0.00 0.13 0 5.00
158 INT267783 Binding of Mvp and IgG 1 0.09 0.89 0 5.00
159 INT343499 CD4 Regulation of HIVEP1 1 0.02 0.16 0 5.00
160 INT272978 Binding of Osr1 and ADHD1 1 0.00 1.91 0 5.00
161 INT325908 Binding of Wbp5 and Fgg 1 0.00 1.2 0 5.00
162 INT325903 Binding of F2 and Gopc 1 0.02 0.26 0 5.00
163 INT270204 TNF Positive_regulation of Il4 1 0.01 0.53 0 5.00
164 INT204085 Binding of LEP and TNF 1 0.37 0.39 0 5.00
165 INT297615 Binding of TSC1 and HDAC9 1 0.01 0.4 0 5.00
166 INT325901 Binding of Dio1 and F2 1 0.01 0.63 0 5.00
167 INT237728 CDR1 Regulation of ADHD1 1 0.03 0.98 0 5.00
168 INT325897 Negative_regulation of Binding of F2 and Wbp5 1 0.01 0.96 0 5.00
169 INT270145 TNF Positive_regulation of IL2 1 0.01 0.53 0 5.00
170 INT284829 Binding of FCGR3A and Ighg1 1 0.00 0.13 0 5.00
171 INT284807 Binding of FCGR3A and IGHG3 1 0.01 0.08 0 5.00
172 INT172345 Eri1 Negative_regulation of Gene_expression of Hras1 1 0.00 0.76 0 5.00
173 INT174290 Lep Positive_regulation of Pomc 2 0.50 0.47 0 5.00
174 INT343500 Binding of CD8A and ERVW-1 1 0.11 0.13 0 5.00
175 INT270205 TNF Positive_regulation of Gene_expression of Csf2 1 0.06 0.55 0 5.00
176 INT218731 Lep Positive_regulation of Gene_expression of Trh 1 0.19 0.07 0 5.00
177 INT270200 TNF Positive_regulation of Il5 1 0.02 0.53 0 5.00
178 INT261034 Adm Positive_regulation of Gmcl1 1 0.03 0.4 0 5.00
179 INT236468 TP53 Positive_regulation of Protein_catabolism of SNRPB 1 0.00 0.52 0 5.00
180 INT284915 Binding of CDKN2B and HIST2H3C 1 0.05 0.43 0 5.00
181 INT172344 Eri1 Negative_regulation of Positive_regulation of Hras1 1 0.00 0.76 0 5.00
182 INT354096 Timp1 Negative_regulation of Positive_regulation of NFKB2 1 0.04 0.94 0 5.00
183 INT325905 Wbp5 Positive_regulation of F2 1 0.01 0.37 0 5.00
184 INT208139 Binding of PITX1 and URI1 1 0.01 0.62 0 5.00
185 INT267778 Binding of Mvp and Gopc 1 0.12 0.83 0 5.00
186 INT325906 Binding of Hps3 and Fgg 1 0.02 0.96 0 5.00
187 INT325899 Binding of Hps3 and F2 1 0.12 2.43 0 5.00
188 INT284995 Binding of HDAC1 and Sin3a 1 0.00 0.13 0 5.00
189 INT320958 Binding of KRT31 and GOPC 1 0.01 0.52 0 5.00
190 INT342439 PPP2CA Negative_regulation of PRMT1 1 0.12 0.63 0 5.00
191 INT349051 Binding of EPCAM and SCFV 1 0.03 1.37 0 5.00
192 INT325907 Positive_regulation of Binding of F2 and Gopc 1 0.03 0.12 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Anorexia. They are ordered first by their pain relevance and then by number of times they were reported in Anorexia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT104551 Gene_expression of Il18 156 0.76 115.51 36.95 100.00
2 INT163329 Negative_regulation of GHRL 5 0.58 7.34 0.65 100.00
3 INT175562 Gene_expression of ENHO 1 0.10 2.85 0.37 100.00
4 INT4786 Gene_expression of GHRL 7 0.78 7.94 1.76 100.00
5 INT7506 Negative_regulation of Ltp 267 0.46 91.01 176.8 100.00
6 INT188844 Gene_expression of AES 44 0.58 33.94 5.85 100.00
7 INT101482 Negative_regulation of Lep 53 0.54 33.59 5.65 100.00
8 INT86280 Positive_regulation of Nfasc 14 0.62 6.56 3.84 100.00
9 INT175563 Negative_regulation of NAA50 9 0.16 11.35 1.53 100.00
10 INT66598 Negative_regulation of GPER 8 0.04 3.83 0.72 100.00
11 INT97443 Positive_regulation of Positive_regulation of LEP 13 0.50 11.91 2.65 99.84
12 INT6277 Positive_regulation of Gene_expression of Pomc 76 0.70 21.45 31.09 99.84
13 INT8050 Positive_regulation of Gene_expression of Nts 10 0.66 2.31 4.69 99.84
14 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31 99.80
15 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 99.80
16 INT5511 Negative_regulation of Gene_expression of Pomc 47 0.59 12.08 23.02 99.80
17 INT9516 Negative_regulation of Gabrg1 149 0.53 27.83 91.02 99.80
18 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 99.66
19 INT214106 Gene_expression of Cartpt 21 0.73 3.68 7.84 99.56
20 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 99.48
21 INT8048 Gene_expression of Nts 45 0.74 8.9 21.84 99.48
22 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9 99.40
23 INT14009 Gene_expression of Sst 66 0.77 19.6 37.3 99.40
24 INT7531 Positive_regulation of Eef1a1 29 0.62 8.16 15.41 99.36
25 INT12315 Gene_expression of Nr3c2 37 0.75 19.28 11.97 99.30
26 INT462 Regulation of Pomc 157 0.62 41.67 67.27 99.20
27 INT6108 Gene_expression of Npy 292 0.78 110.65 148.21 99.14
28 INT5034 Negative_regulation of Insr 100 0.55 28.08 54.5 99.06
29 INT3002 Binding of SUGT1 62 0.24 55.9 14.91 98.94
30 INT47387 Negative_regulation of Positive_regulation of GOT1 2 0.26 1.04 0.43 98.92
31 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22 98.72
32 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 98.68
33 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2 98.58
34 INT75846 Positive_regulation of MC4R 7 0.70 5.73 1.05 98.52
35 INT2862 Positive_regulation of Localization of Cck 108 0.70 20.75 94.25 98.44
36 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 98.44
37 INT287 Localization of Cck 518 0.81 86.84 364.04 98.26
38 INT17925 Transcription of Npy 53 0.72 15.75 25.56 98.04
39 INT8380 Positive_regulation of Gene_expression of Npy 49 0.70 19.62 24.13 98.04
40 INT7565 Transcription of Pomc 69 0.72 14.46 27.41 98.04
41 INT53773 Positive_regulation of Transcription of Npy 11 0.70 3.75 6.29 98.04
42 INT28871 Regulation of CSRP1 8 0.46 6.29 4.04 98.02
43 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12 97.84
44 INT105149 Gene_expression of PTBP1 10 0.75 12.27 1.09 97.80
45 INT5283 Positive_regulation of Npy 191 0.70 66.77 109.2 97.60
46 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 97.60
47 INT6511 Positive_regulation of AFP 76 0.70 70.15 7.28 97.60
48 INT12281 Negative_regulation of Gene_expression of Npy 23 0.59 7.45 13.41 97.56
49 INT5337 Negative_regulation of Npy 87 0.59 19.6 46.75 97.56
50 INT297626 Gene_expression of RLN3 3 0.11 5.07 0.3 97.44
51 INT297627 Positive_regulation of Gene_expression of RLN3 3 0.08 3.06 0.08 97.44
52 INT2323 Gene_expression of Trh 146 0.78 29.92 49.5 97.34
53 INT200738 Gene_expression of HIST2H4A 7 0.18 4.65 0.91 97.32
54 INT265661 Positive_regulation of Gene_expression of HIST2H4A 2 0.09 2.69 0.28 97.32
55 INT52180 Binding of Aes 38 0.42 23.16 6.7 97.28
56 INT104350 Regulation of Agrp 9 0.52 3.53 0.81 97.28
57 INT187358 Localization of Kcnn3 2 0.72 1.65 0.51 97.24
58 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 97.20
59 INT174725 Positive_regulation of Localization of ESR1 8 0.47 2.45 0.41 97.20
60 INT176571 Negative_regulation of Positive_regulation of ESR1 5 0.47 3.15 0.17 97.20
61 INT9473 Binding of MUC1 66 0.48 46.77 2.36 97.12
62 INT36970 Positive_regulation of Acpp 2 0.20 1.68 0.2 97.00
63 INT249561 Positive_regulation of Psmd1 12 0.37 7.32 5.06 96.72
64 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 96.68
65 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69 96.68
66 INT27627 Binding of Rac1 41 0.41 22.88 13.68 96.64
67 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52 96.40
68 INT92354 Localization of ESR1 77 0.75 33.04 15.51 96.40
69 INT153772 Negative_regulation of Localization of ESR1 7 0.54 4.42 0.27 96.40
70 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 96.32
71 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 96.32
72 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 96.32
73 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 96.32
74 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 96.32
75 INT8632 Regulation of Nfasc 15 0.54 2.87 9.08 96.16
76 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 96.00
77 INT149091 Gene_expression of Ghsr 42 0.76 5.11 4.6 96.00
78 INT224959 Positive_regulation of Gene_expression of Ghsr 5 0.45 1.09 0.5 96.00
79 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17 95.80
80 INT66599 Gene_expression of MC4R 16 0.78 12.37 3.12 95.76
81 INT231014 Negative_regulation of MC4R 4 0.43 5.52 0.58 95.76
82 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 95.56
83 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 95.56
84 INT173519 Positive_regulation of Localization of IFNA1 27 0.49 24.48 3.9 95.56
85 INT149090 Positive_regulation of Ghsr 10 0.70 2.33 1.06 95.52
86 INT8546 Positive_regulation of MUC16 99 0.69 74.98 11.26 95.32
87 INT11506 Binding of MUC16 20 0.48 22.89 1.03 95.32
88 INT214132 Regulation of Nucb2 2 0.04 0.33 0.14 95.00
89 INT99331 Binding of Agrp 6 0.40 1.08 2.3 94.84
90 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47 94.84
91 INT89184 Gene_expression of Mc4r 55 0.77 23.85 10.65 94.72
92 INT210838 Positive_regulation of Mc4r 17 0.53 6.79 3.06 94.72
93 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 94.68
94 INT89181 Gene_expression of Mc3r 33 0.77 22.48 11.85 94.36
95 INT3948 Regulation of Cck 291 0.62 58.07 255.88 94.24
96 INT214113 Transcription of Ntrk2 2 0.72 1.84 0.96 94.24
97 INT6481 Binding of TNF 624 0.48 510.2 214.82 94.20
98 INT73338 Gene_expression of Faah 21 0.77 6.72 10.73 94.04
99 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64 93.84
100 INT94464 Negative_regulation of Hand1 44 0.41 31.5 12.39 93.72
101 INT163780 Gene_expression of Nucb2 11 0.77 5.1 2.94 93.68
102 INT5338 Regulation of Npy 92 0.62 25.54 51.24 93.44
103 INT36449 Negative_regulation of G6PD 74 0.59 54.15 8.85 93.44
104 INT89180 Gene_expression of Agrp 54 0.78 14.29 8.84 93.40
105 INT81496 Gene_expression of CNR2 68 0.75 30.04 24.92 93.40
106 INT6323 Positive_regulation of Gabrg1 213 0.70 45.08 124.34 93.12
107 INT74376 Gene_expression of Cnr1 173 0.78 73.43 89.7 93.08
108 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95 93.04
109 INT187726 Positive_regulation of Localization of LEP 5 0.50 5.31 0.41 93.04
110 INT297621 Positive_regulation of RLN3 1 0.05 2.79 0 93.04
111 INT199004 Gene_expression of ARMC9 43 0.58 17.72 1.32 93.00
112 INT150138 Regulation of Gene_expression of Kcnn3 1 0.54 1.96 0 92.96
113 INT150144 Gene_expression of Kcnn3 31 0.78 7.67 4.24 92.96
114 INT150145 Regulation of Kcnn3 2 0.45 1.11 0.71 92.96
115 INT275245 Positive_regulation of HIST2H2BE 2 0.15 1.94 0 92.76
116 INT15652 Positive_regulation of ENO2 37 0.68 33.39 5.02 92.60
117 INT182723 Negative_regulation of Localization of SHE 1 0.11 1.09 0 92.56
118 INT214115 Regulation of Gene_expression of Lep 9 0.61 7.37 1.44 92.48
119 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68 92.40
120 INT106554 Positive_regulation of Gene_expression of Bdnf 73 0.70 42.58 30.77 92.40
121 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 92.32
122 INT221097 Negative_regulation of Atp8a1 15 0.57 10.52 2.65 92.28
123 INT60600 Binding of PSS 5 0.32 3.59 1.42 92.04
124 INT182722 Localization of SHE 1 0.20 1.43 0 92.00
125 INT37390 Regulation of Crp 39 0.46 28.74 11.45 91.96
126 INT37485 Regulation of RAPGEF5 10 0.44 6.64 1.51 91.80
127 INT125147 Binding of Mc4r 10 0.41 3.55 1.08 91.72
128 INT214095 Binding of Mc3r 1 0.32 0.67 0.41 91.72
129 INT214124 Negative_regulation of Binding of Mc4r 1 0.42 0.19 0.05 91.72
130 INT214107 Negative_regulation of Binding of Mc3r 1 0.36 0.19 0.05 91.72
131 INT326328 Positive_regulation of Positive_regulation of ARMC9 1 0.02 0.63 0 91.56
132 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 91.48
133 INT15458 Gene_expression of NPY 50 0.76 22.67 23.03 91.28
134 INT197721 Positive_regulation of ARMC9 36 0.35 20.08 1.03 91.12
135 INT152915 Localization of Vgf 2 0.70 0.95 0.54 91.04
136 INT1378 Negative_regulation of Regulation of Prl 27 0.43 9.16 9.9 90.96
137 INT871 Negative_regulation of Gene_expression of Prl 53 0.58 18.89 17.79 90.96
138 INT101484 Regulation of Positive_regulation of Lep 3 0.45 1.68 0.61 90.92
139 INT172343 Negative_regulation of Gene_expression of Agrp 10 0.59 1.79 0.53 90.92
140 INT65356 Localization of LEP 46 0.79 41.17 5.43 90.88
141 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61 90.76
142 INT75908 Regulation of LEP 77 0.60 60.16 15.19 90.56
143 INT1438 Localization of Pomc 360 0.81 101.26 116.47 90.56
144 INT25610 Positive_regulation of Gene_expression of Il1 136 0.67 104.43 43.86 90.16
145 INT177581 Regulation of Fig4 113 0.41 39.26 27.75 90.08
146 INT31649 Positive_regulation of Tbr1 1 0.49 0.73 0.42 90.00
147 INT15190 Regulation of Npy 17 0.61 5.33 5.84 89.96
148 INT152916 Gene_expression of Vgf 2 0.67 0.95 0.53 89.92
149 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 89.88
150 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97 89.88
151 INT9796 Gene_expression of Cck 63 0.78 11.44 32.09 89.84
152 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 89.60
153 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 89.36
154 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 89.28
155 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 89.08
156 INT224966 Positive_regulation of Gene_expression of Snord116 3 0.50 1.72 0.17 89.08
157 INT27266 Regulation of Gene_expression of Pomc 41 0.62 6.74 14.59 88.96
158 INT224974 Negative_regulation of Gene_expression of Snord116 4 0.59 0.91 0.08 88.92
159 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77 88.80
160 INT224953 Gene_expression of Snord116 23 0.78 9.86 0.89 88.80
161 INT141014 Positive_regulation of Gene_expression of Il18 46 0.68 47.63 13.3 88.76
162 INT206656 Phosphorylation of NAPEPLD 1 0.08 0.99 0.16 88.76
163 INT75907 Binding of LEP 53 0.46 46.65 8.44 88.72
164 INT128415 Positive_regulation of Agrp 36 0.64 11.87 3.91 88.64
165 INT8047 Positive_regulation of Nts 20 0.67 7.96 10.35 88.64
166 INT174281 Positive_regulation of Positive_regulation of Agrp 4 0.41 1.71 0.91 88.64
167 INT6510 Gene_expression of AFP 130 0.78 119.2 9.19 88.12
168 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 88.08
169 INT25797 Positive_regulation of OR2AL1P 5 0.09 5.14 0.99 88.08
170 INT14031 Gene_expression of Npy 107 0.78 36.48 35.4 87.88
171 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33 87.68
172 INT55034 Positive_regulation of Adm 27 0.61 14.1 6.13 87.52
173 INT22000 Positive_regulation of Sst 25 0.70 14.82 13.6 87.48
174 INT124705 Binding of Il18 29 0.47 19.02 5.59 87.40
175 INT25607 Binding of Il1 82 0.47 64.4 23.9 87.40
176 INT172339 Positive_regulation of Gene_expression of Agrp 7 0.70 2.26 0.34 87.36
177 INT162 Regulation of Prl 794 0.62 165.01 322.24 87.28
178 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 87.12
179 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 86.96
180 INT119818 Negative_regulation of CHGA 10 0.57 8.21 2.04 86.76
181 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 86.56
182 INT231565 Positive_regulation of YWHAE 4 0.23 3.07 0.49 86.32
183 INT214 Localization of AVP 370 0.81 208.51 91.09 86.24
184 INT119606 Regulation of Gene_expression of LEP 17 0.45 17.96 3.75 86.16
185 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 86.16
186 INT6278 Negative_regulation of Gene_expression of Pomc 35 0.59 11.07 14.8 86.04
187 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41 85.80
188 INT214114 Transcription of Nucb2 1 0.69 0.15 0.06 85.60
189 INT2064 Positive_regulation of BTG3 29 0.49 25.58 15.37 85.36
190 INT34590 Gene_expression of ALPP 199 0.75 89.85 15.1 85.28
191 INT284973 Negative_regulation of Negative_regulation of HDAC1 1 0.20 1.59 0.04 85.12
192 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 85.12
193 INT52924 Negative_regulation of GSR 49 0.58 28.08 9.28 85.04
194 INT20378 Localization of Hand1 53 0.71 41.96 13.31 85.00
195 INT214137 Localization of PYY3 2 0.68 0.51 0.04 84.92
196 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 84.88
197 INT297628 Negative_regulation of ZNF275 1 0.00 3.2 0 84.84
198 INT112017 Regulation of Hand2 77 0.36 62.23 18.04 84.72
199 INT173505 Localization of Hand2 63 0.57 45.32 13.66 84.72
200 INT21646 Positive_regulation of Npy 40 0.70 31.31 13.57 84.56
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