D:Aortitis

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pChart

Disease Term
Synonyms Aortitides
Documents 116
Hot Single Events 5
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Aortitis. They are ordered first by their relevance to Aortitis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41 5.00
2 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09 5.00
3 INT277832 Binding of TNFRSF1B and NPEPPS 1 0.01 1.1 0.88 5.00
4 INT277831 Binding of TNFRSF1A and NPEPPS 1 0.01 1.1 0.87 5.00
5 INT329670 Csf2 Regulation of Col7a1 1 0.03 0.4 0.17 5.00
6 INT198307 IL10 Positive_regulation of Gene_expression of IGHG3 2 0.01 1.21 0.15 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Aortitis. They are ordered first by their pain relevance and then by number of times they were reported in Aortitis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 96.72
2 INT16449 Binding of IGHG3 67 0.48 39.55 10.59 94.88
3 INT124061 Binding of YWHAE 3 0.30 3.43 0.4 94.88
4 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 94.36
5 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 88.40
6 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 75.28
7 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 49.84
8 INT176445 Protein_catabolism of Gopc 23 0.76 7.57 0.75 29.60
9 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 25.76
10 INT116282 Gene_expression of Mmp13 83 0.75 45.4 20.18 24.12
11 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 23.88
12 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01 23.36
13 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25 18.76
14 INT103603 Negative_regulation of Gene_expression of Mmp2 16 0.51 12.29 2.47 18.76
15 INT3512 Gene_expression of Igha 9 0.60 7.71 1.13 17.60
16 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 16.96
17 INT317979 Positive_regulation of Transcription of Mmp2 4 0.46 2.63 1.37 12.76
18 INT105985 Transcription of Mmp9 11 0.66 8.55 3.02 11.76
19 INT138141 Transcription of Mmp2 10 0.64 6.52 2.99 11.76
20 INT116280 Transcription of Mmp13 11 0.67 6.52 2.06 11.76
21 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
22 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
23 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
24 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 5.00
25 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
26 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 5.00
27 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 5.00
28 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 5.00
29 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
30 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 5.00
31 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 5.00
32 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 5.00
33 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
34 INT60710 Gene_expression of Col7a1 217 0.78 113.2 35.2 5.00
35 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 5.00
36 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
37 INT8775 Binding of IGHE 167 0.48 102.61 23.54 5.00
38 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05 5.00
39 INT17848 Binding of PTGS2 70 0.46 32.1 20.6 5.00
40 INT18311 Positive_regulation of CD8A 145 0.69 113.48 19.44 5.00
41 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 5.00
42 INT65260 Positive_regulation of Col7a1 95 0.69 61.73 18.42 5.00
43 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89 5.00
44 INT56651 Binding of HLA-DRB1 58 0.48 52.25 13.68 5.00
45 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 5.00
46 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 5.00
47 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 5.00
48 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 5.00
49 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 5.00
50 INT25381 Localization of Csf2 62 0.76 47.48 9.03 5.00
51 INT86705 Gene_expression of BTG3 41 0.65 37.29 8.29 5.00
52 INT75932 Binding of Csf2 45 0.37 33.2 8.01 5.00
53 INT1123 Positive_regulation of CD79A 74 0.70 51.96 7.14 5.00
54 INT13520 Binding of HLA-DRB4 30 0.42 32.65 6.74 5.00
55 INT23246 Gene_expression of HLA-DRB4 37 0.64 36.79 6.61 5.00
56 INT65265 Positive_regulation of Gene_expression of Col7a1 48 0.69 23.81 6.16 5.00
57 INT122165 Binding of TNFRSF1B 8 0.28 7.46 4.87 5.00
58 INT2065 Binding of BTG3 15 0.36 10.9 4.65 5.00
59 INT172173 Protein_catabolism of TNF 16 0.96 9.95 3.79 5.00
60 INT62386 Negative_regulation of Gene_expression of IGHG3 12 0.20 7.94 3.62 5.00
61 INT112784 Positive_regulation of Positive_regulation of IFNG 11 0.49 7.84 2.18 5.00
62 INT181396 Transcription of Csf2 15 0.48 6.38 2.17 5.00
63 INT148705 Binding of TNFRSF1A 8 0.38 5.19 1.81 5.00
64 INT25384 Positive_regulation of Localization of Csf2 11 0.66 7.81 1.62 5.00
65 INT159489 Positive_regulation of Positive_regulation of Csf2 6 0.42 6.02 1.61 5.00
66 INT27585 Positive_regulation of smc 9 0.58 3.2 1.47 5.00
67 INT64952 Binding of HLA-DQA2 11 0.10 7.23 1.39 5.00
68 INT209962 Binding of RDBP 4 0.11 2.93 1.27 5.00
69 INT37679 Positive_regulation of HLA-DRB4 12 0.34 11.93 1.16 5.00
70 INT175689 Localization of smc 3 0.21 2.4 0.54 5.00
71 INT179654 Positive_regulation of Eln 5 0.44 4.3 0.43 5.00
72 INT197157 Gene_expression of CAPN7 19 0.51 11.33 0.4 5.00
73 INT329668 Positive_regulation of Localization of smc 1 0.13 0.4 0.17 5.00
74 INT224838 Positive_regulation of Transcription of Csf2 4 0.42 1.49 0.15 5.00
75 INT146474 Gene_expression of tch 2 0.58 1.08 0.07 5.00
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