D:Apert Syndrome

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Disease Term
Synonyms ACROCEPHALOPOLYSYNDACTYLY SYNDROME, Acrocephalosyndactylia, Acrocephalosyndactylias, Acrocephalosyndactyly, ACROCEPHALOSYNDACTYLY DISORDER, ACROENCEPHALOSYNDACTYLY, APERT CROUZON SYNDROME, Apert Disease, APERT S DISORDER, PFEIFFER SYNDROME, SAETHRE CHOTZEN SYNDROME
Documents 13
Hot Single Events 0
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Apert Syndrome. They are ordered first by their relevance to Apert Syndrome and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT189021 NOX5 Positive_regulation of ROS1 1 0.26 0.2 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Apert Syndrome. They are ordered first by their pain relevance and then by number of times they were reported in Apert Syndrome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 5.00
2 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
3 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
4 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 5.00
5 INT66383 Phosphorylation of Prkaca 143 0.80 30.85 43.38 5.00
6 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
7 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 5.00
8 INT69435 Negative_regulation of ROS1 74 0.51 50.38 13.71 5.00
9 INT69436 Negative_regulation of Gene_expression of ROS1 81 0.38 46.58 12.22 5.00
10 INT112003 Localization of ROS1 94 0.73 66.32 12.16 5.00
11 INT116433 Gene_expression of CYBB 93 0.70 50.44 11.91 5.00
12 INT94784 Binding of ROS1 113 0.40 71.57 10.26 5.00
13 INT16131 Negative_regulation of GBE1 37 0.30 10.32 8.15 5.00
14 INT1755 Gene_expression of GBE1 28 0.26 8.32 5.18 5.00
15 INT35765 Gene_expression of TXNRD1 47 0.56 9.16 4.43 5.00
16 INT113785 Negative_regulation of Eef1a2 15 0.31 1.33 1.48 5.00
17 INT161807 Phosphorylation of ROS1 10 0.43 4.86 0.62 5.00
18 INT189030 Phosphorylation of PTPN3 3 0.31 1.17 0.39 5.00
19 INT189038 Regulation of Protein_catabolism of IL9 2 0.09 0.07 0.24 5.00
20 INT189037 Protein_catabolism of IL9 2 0.18 0.07 0.21 5.00
21 INT189039 Negative_regulation of PTPN3 3 0.21 1.01 0.16 5.00
22 INT189034 Gene_expression of NOX5 5 0.48 1.99 0.1 5.00
23 INT189029 Protein_catabolism of PRRX1 1 0.86 0.07 0 5.00
24 INT189032 Positive_regulation of Phosphorylation of PTPN3 1 0.06 0.36 0 5.00
25 INT189036 Regulation of Protein_catabolism of PRRX1 1 0.44 0.07 0 5.00
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