D:Apnoea

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Disease Term
Synonyms Apnea, APNEAS, Hypopnoea, HYPOPNOEA SYNDROME, Obstructive Sleep Apnea, Obstructive Sleep Apnoea, Post Apnea, Post Apnoea, Sahs, Sleep Apnea, Sleep Apnoea
Documents 1221
Hot Single Events 200
Hot Interactions 19

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Apnoea. They are ordered first by their relevance to Apnoea and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT267707 Binding of Tnf and ARID1B 2 0.20 8.2 0.54 100.00
2 INT267684 Binding of INS and ARID1B 3 0.10 6.08 0.09 100.00
3 INT350016 Binding of CD40LG and ARID1B 1 0.01 3.26 0.21 100.00
4 INT350015 ARID1B Regulation of Localization of INS 1 0.03 2.6 0.04 100.00
5 INT350012 Binding of TNF and ARID1B 1 0.01 2.25 0.12 100.00
6 INT350019 Regulation of Binding of Tnf and ARID1B 1 0.04 1.34 0.1 100.00
7 INT350020 ARID1B Regulation of Positive_regulation of Tnf 1 0.04 1.78 0.16 100.00
8 INT350013 ARID1B Regulation of Positive_regulation of NFKB1 1 0.00 1.77 0.16 100.00
9 INT249046 Binding of LEP and ARID1B 1 0.01 1.3 0.03 100.00
10 INT142932 Binding of Arid1a and Samsn1 1 0.01 1.55 0 100.00
11 INT30378 Binding of Sst and Penk 1 0.28 0.52 1.01 96.08
12 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 95.96
13 INT143747 Binding of IL6 and LEP 2 0.04 4.05 0.38 93.24
14 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42 93.24
15 INT249047 CENPJ Negative_regulation of LEP 1 0.22 0.8 0 87.08
16 INT350011 Binding of BMI1 and IL6 1 0.01 0.58 0.1 84.76
17 INT217106 Binding of Hoxa2 and Hoxb2 1 0.34 0.08 0.04 82.04
18 INT327808 EPO Regulation of VEGFA 1 0.07 1.36 0.12 81.52
19 INT249045 CENPJ Regulation of Regulation of LEP 1 0.14 0.81 0 81.12
20 INT242324 Lep Regulation of Gene_expression of Ucp1 1 0.58 1.47 0.09 73.36
21 INT217109 Hoxa2 Positive_regulation of Egr2 1 0.56 0.43 0 71.20
22 INT350010 Binding of IL6 and AHI1 1 0.01 0.29 0.06 67.56
23 INT217111 Binding of Egr2 and Hoxa2 1 0.35 0.21 0.03 62.24
24 INT217113 Egr2 Regulation of Binding of Egr2 and Hoxa2 1 0.30 0.21 0.03 62.24
25 INT217114 Hoxa2 Regulation of Binding of Egr2 and Hoxa2 1 0.26 0.21 0.03 62.24
26 INT186548 Binding of KRT1 and MAX 1 0.01 0.15 0 60.72
27 INT306795 Binding of LEP and SFTPD 1 0.08 1.13 0.23 58.72
28 INT153019 nct Positive_regulation of Transcription of Th 1 0.19 0.61 0.32 58.20
29 INT153020 nct Positive_regulation of Gene_expression of Th 1 0.19 0.61 0.32 58.20
30 INT223088 Binding of ELF3 and NAGLU 1 0.14 0.84 0.09 55.28
31 INT223089 Binding of IDS and NAGLU 1 0.26 0.72 0.09 53.96
32 INT246336 Fig4 Regulation of Localization of Nts 1 0.18 0 0.66 30.72
33 INT246335 Fig4 Regulation of Localization of P2rx7 1 0.01 0 0.67 29.84
34 INT267686 Binding of RYBP and CENPJ 1 0.01 0.12 0.03 26.88
35 INT345966 Binding of Arid1a and al44 1 0.00 1.56 0.05 20.92
36 INT345965 Binding of Lep and al44 1 0.01 1.43 0.05 20.92
37 INT305270 Lep Negative_regulation of Localization of Car2 1 0.16 1.28 0 10.64
38 INT303600 IGF1 Regulation of Gene_expression of GH1 1 0.39 0.83 0.14 9.72
39 INT295292 Jun Positive_regulation of Transcription of Nos2 1 0.01 0 0 9.60
40 INT308702 Binding of AQP4 and CD40LG 1 0.10 0 0 8.72
41 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
42 INT250976 Binding of FMOD and IL8 1 0.08 1.26 0.91 5.00
43 INT132318 Ghrl Positive_regulation of Localization of GH1 5 0.32 4.49 0.84 5.00
44 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83 5.00
45 INT187290 Binding of HEY1 and Gtf3a 1 0.00 6.18 0.83 5.00
46 INT313993 Ros1 Positive_regulation of Nfkb1 1 0.05 1.61 0.68 5.00
47 INT169648 IGHG3 Regulation of AQP4 3 0.02 4.63 0.55 5.00
48 INT269057 Il6 Positive_regulation of Crp 1 0.37 1.83 0.51 5.00
49 INT27730 Binding of ALB and Shbg 2 0.01 0.44 0.5 5.00
50 INT327806 Binding of ADORA1 and ADORA2A 1 0.06 0.18 0.49 5.00
51 INT328385 Binding of GHS and Ghrl 1 0.15 1.89 0.45 5.00
52 INT269061 Binding of Il6 and Il6ra 3 0.04 2.59 0.45 5.00
53 INT328377 Binding of GAST and Ghrl 1 0.03 0.62 0.43 5.00
54 INT250975 Binding of FMOD and CSAD 1 0.01 0.86 0.41 5.00
55 INT292928 Olr717 Regulation of Grip2 1 0.00 0 0.37 5.00
56 INT344238 MCRS1 Regulation of TREX1 1 0.08 1.02 0.34 5.00
57 INT207184 Binding of Adipoq and Lep 1 0.25 2.45 0.33 5.00
58 INT308701 Binding of AQP4 and DDX41 1 0.15 3.53 0.32 5.00
59 INT269064 Il6 Positive_regulation of Gene_expression of Cybb 1 0.75 0.79 0.31 5.00
60 INT328299 Binding of GHRH and GHS 1 0.07 2.21 0.31 5.00
61 INT278018 Gh Negative_regulation of Phosphorylation of Ins1 1 0.13 1.5 0.29 5.00
62 INT278015 Gh Regulation of Ins1 1 0.10 1.47 0.27 5.00
63 INT308708 DDX41 Regulation of AQP4 1 0.10 2.79 0.26 5.00
64 INT278012 Gh Positive_regulation of Gene_expression of Ins1 1 0.11 1.24 0.26 5.00
65 INT278016 Gh Positive_regulation of Localization of Ins1 1 0.16 1.22 0.26 5.00
66 INT269060 Il6 Positive_regulation of Cybb 1 0.75 0.65 0.26 5.00
67 INT328378 GH1 Regulation of Gene_expression of Ghrl 1 0.02 0.39 0.25 5.00
68 INT328382 Positive_regulation of Ghrl Positive_regulation of Localization of INS 1 0.03 1.08 0.23 5.00
69 INT269066 Binding of Hspa8 and Il6 1 0.00 0.74 0.23 5.00
70 INT207845 Binding of INS and Hypism 3 0.04 2.88 0.22 5.00
71 INT351318 Binding of CYP2C19 and Cyp1a2 1 0.01 0.28 0.22 5.00
72 INT207185 Binding of Bmi1 and Lep 1 0.01 1.7 0.21 5.00
73 INT192109 PAH Positive_regulation of Binding of COL7A1 1 0.04 1.45 0.2 5.00
74 INT327814 Rab8a Regulation of Regulation of Lep 1 0.01 0.15 0.19 5.00
75 INT327813 Rab8a Regulation of Lep 1 0.01 0.15 0.19 5.00
76 INT269071 Binding of IL6 and Il6 1 0.40 0.73 0.19 5.00
77 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19 5.00
78 INT217665 ADIPOQ Positive_regulation of INS 2 0.06 1.8 0.19 5.00
79 INT328310 DBT Positive_regulation of Localization of GH1 1 0.00 0 0.19 5.00
80 INT207186 Binding of Adipoq and Bmi1 1 0.01 1.65 0.18 5.00
81 INT274353 DST Regulation of Gopc 1 0.00 0 0.17 5.00
82 INT328386 GHS Positive_regulation of Localization of Ghrl 1 0.10 0.88 0.17 5.00
83 INT328379 Ghrl Positive_regulation of CRH 1 0.16 1.17 0.16 5.00
84 INT278020 Binding of Gh and Sst 1 0.18 0.16 0.15 5.00
85 INT217667 LEP Negative_regulation of Localization of INS 1 0.15 1.18 0.14 5.00
86 INT217664 LEP Negative_regulation of INS 1 0.15 1.18 0.14 5.00
87 INT269054 Positive_regulation of Il6 Positive_regulation of Cybb 1 0.54 0.3 0.14 5.00
88 INT308709 Positive_regulation of Binding of AQP4 and DDX41 1 0.18 1.19 0.14 5.00
89 INT269070 Regulation of Il6 Positive_regulation of Cybb 1 0.29 0.3 0.14 5.00
90 INT328374 GHRH Positive_regulation of Ghrl 1 0.13 0.26 0.13 5.00
91 INT328384 Ghrl Positive_regulation of ALPL 1 0.01 0.93 0.13 5.00
92 INT328309 GHS Positive_regulation of Localization of GH1 1 0.04 0.99 0.12 5.00
93 INT269055 Il6 Positive_regulation of Gene_expression of Gopc 1 0.21 0.06 0.12 5.00
94 INT270746 INS Regulation of LEP 1 0.07 0.72 0.11 5.00
95 INT328313 Binding of CD36 and LDLR 1 0.00 0.63 0.11 5.00
96 INT328294 GHS Positive_regulation of Localization of GHRH 1 0.10 0.12 0.11 5.00
97 INT328370 Binding of CD36 and Fabp1 1 0.01 0.64 0.11 5.00
98 INT328364 Binding of GHRH and Ghrl 1 0.09 0.2 0.1 5.00
99 INT328297 GHRH Positive_regulation of Transcription of GH1 1 0.04 0.26 0.1 5.00
100 INT246478 Binding of SERPINE1 and ANGPTL5 1 0.01 1.32 0.1 5.00
101 INT328372 Ghrl Positive_regulation of Transcription of GH1 1 0.04 0.27 0.1 5.00
102 INT308704 Binding of DDX41 and M1 1 0.02 2.09 0.1 5.00
103 INT208983 Binding of Ca2 and Kcnma1 2 0.01 0.28 0.1 5.00
104 INT306794 Binding of LEP and COPD 1 0.15 3.94 0.09 5.00
105 INT277890 Binding of Ids and Tas2r111-ps2 1 0.08 0.5 0.09 5.00
106 INT323071 Binding of RT1-DOa and Ppara 1 0.13 0.74 0.09 5.00
107 INT277889 Regulation of Binding of Ids and Tas2r111-ps2 1 0.09 0.5 0.09 5.00
108 INT328311 Binding of GH1 and GHS 1 0.02 0.14 0.09 5.00
109 INT269069 Binding of Cyba and Cybb 1 0.18 0.18 0.09 5.00
110 INT269056 Positive_regulation of Binding of Cyba and Cybb 1 0.24 0.18 0.09 5.00
111 INT328373 Negative_regulation of Ghrl Positive_regulation of Localization of GH1 1 0.05 0.31 0.08 5.00
112 INT305257 Obsty1 Regulation of Gene_expression of Mapk1 1 0.03 2.05 0.08 5.00
113 INT305274 Obsty1 Regulation of Gene_expression of Prkag1 1 0.01 0.94 0.08 5.00
114 INT328302 Gene_expression of GHS Positive_regulation of Gene_expression of GH1 1 0.03 0.17 0.08 5.00
115 INT328306 GH1 Positive_regulation of Localization of INS 1 0.01 0.12 0.07 5.00
116 INT269063 Gene_expression of Il6 Positive_regulation of Cybb 1 0.47 0.33 0.07 5.00
117 INT352579 CNTF Negative_regulation of Gene_expression of NPY 1 0.17 0.89 0.07 5.00
118 INT328366 GPR39 Regulation of Localization of Ghrl 1 0.11 0.2 0.07 5.00
119 INT328380 AR Negative_regulation of Gene_expression of Ghrl 1 0.01 0.55 0.07 5.00
120 INT213261 TNF Positive_regulation of CRP 1 0.24 1.59 0.06 5.00
121 INT328305 GHS Positive_regulation of Localization of INS 1 0.02 0.07 0.05 5.00
122 INT260728 Binding of Samsn1 and NAFLD2 1 0.00 1.15 0.05 5.00
123 INT310674 Positive_regulation of Binding of ARSB and ELF3 1 0.07 2.46 0.05 5.00
124 INT295295 Tlr4 Positive_regulation of Ca2 1 0.00 0.34 0.05 5.00
125 INT328387 INS Negative_regulation of Gene_expression of Ghrl 1 0.01 0.6 0.05 5.00
126 INT328371 Ghrl Negative_regulation of INS 1 0.03 0.13 0.05 5.00
127 INT328376 Ghrl Negative_regulation of SST 1 0.03 0.13 0.05 5.00
128 INT328383 Ghrl Negative_regulation of MBOAT4 1 0.26 0 0.05 5.00
129 INT328367 KISS1 Positive_regulation of Localization of Gnrh1 1 0.00 0 0.05 5.00
130 INT328308 CRH Negative_regulation of KISS1 1 0.02 0 0.05 5.00
131 INT328292 KISS1 Positive_regulation of Localization of PLOD1 1 0.00 0 0.05 5.00
132 INT328293 Binding of JAG2 and GHS 1 0.03 0.09 0.05 5.00
133 INT217666 ADIPOQ Regulation of Gene_expression of INS 1 0.03 1.99 0.05 5.00
134 INT327821 GPRC6A Regulation of Gene_expression of Lep 1 0.00 0.5 0.05 5.00
135 INT236147 Binding of Ins1 and Ptpn1 2 0.03 1.29 0.05 5.00
136 INT295294 Tlr4 Positive_regulation of Mapk14 1 0.00 0.39 0.05 5.00
137 INT327822 INCENP Regulation of Gene_expression of Lep 1 0.00 0.5 0.05 5.00
138 INT310727 Binding of DKC1 and TERT 1 0.23 0.91 0.05 5.00
139 INT328365 Binding of JAG2 and Ghrl 1 0.03 0.07 0.05 5.00
140 INT310675 Binding of ARSB and ELF3 1 0.06 2.4 0.05 5.00
141 INT213263 INS Positive_regulation of EDN1 1 0.12 0.54 0.04 5.00
142 INT213608 Binding of PER2 and CLOCK 1 0.22 0.65 0.04 5.00
143 INT329015 Binding of APCS and SRGN 1 0.08 1.14 0.04 5.00
144 INT326625 Binding of ALB and Trf 1 0.01 0.64 0.04 5.00
145 INT267685 Binding of CENPJ and ARID1B 1 0.09 0.58 0.04 5.00
146 INT328303 Gene_expression of GHS Positive_regulation of Gene_expression of GHRH 1 0.09 0.19 0.04 5.00
147 INT296893 Nps Negative_regulation of Gene_expression of REN 1 0.00 1.05 0.04 5.00
148 INT328301 GHRH Positive_regulation of SCG5 1 0.24 0.13 0.04 5.00
149 INT328363 Ghrl Negative_regulation of PLOD1 1 0.02 0.11 0.04 5.00
150 INT213607 Binding of CSNK1D and CLOCK 1 0.27 0.65 0.04 5.00
151 INT290877 Binding of Bcl2a1c and Lepr 1 0.00 0.87 0.04 5.00
152 INT328295 GHRH Positive_regulation of GHS 1 0.10 0.13 0.04 5.00
153 INT269065 Il6 Regulation of Gene_expression of Cybb 1 0.66 0.12 0.04 5.00
154 INT328332 Ghrl Negative_regulation of Abo 1 0.01 0 0.04 5.00
155 INT269058 Positive_regulation of Il6 Positive_regulation of Gene_expression of Cybb 1 0.50 0.06 0.03 5.00
156 INT236149 Binding of Ncoa1 and Ppara 1 0.07 0 0.03 5.00
157 INT236146 Binding of Ppara and Pprc1 1 0.01 0 0.03 5.00
158 INT328312 GHS Positive_regulation of Localization of PRL 1 0.02 0.21 0.03 5.00
159 INT334918 GNRH1 Positive_regulation of Gene_expression of FSHR 2 0.11 1.27 0.03 5.00
160 INT328362 LYPLA1 Regulation of Ghrl 1 0.04 0.07 0.03 5.00
161 INT213262 IL6 Positive_regulation of CYP19A1 1 0.11 1.63 0.03 5.00
162 INT327451 HTN1 Positive_regulation of Adra1a 1 0.00 1.36 0.03 5.00
163 INT246480 Binding of ALB and SHBG 2 0.14 1.45 0.03 5.00
164 INT328381 Ghrl Positive_regulation of NPY 1 0.06 0.15 0.03 5.00
165 INT328304 POMC Positive_regulation of Localization of CRH 1 0.07 0.22 0.03 5.00
166 INT336576 Binding of HCRTR1 and IGHG3 1 0.01 5.01 0 5.00
167 INT217112 Egr2 Regulation of Hoxa2 1 0.69 0 0 5.00
168 INT277892 IDS Regulation of Ids 1 0.18 0.41 0 5.00
169 INT324347 Binding of UMOD and Scr 1 0.20 2.23 0 5.00
170 INT305279 Lep Regulation of Gene_expression of Akt1 1 0.18 0.83 0 5.00
171 INT328298 GHRH Negative_regulation of Localization of GHS 1 0.08 0.84 0 5.00
172 INT324342 UMOD Positive_regulation of Scr 1 0.17 1.29 0 5.00
173 INT278014 Ptprf Regulation of Localization of Gh 1 0.61 0.31 0 5.00
174 INT305266 Obsty1 Negative_regulation of Phosphorylation of Mapk14 1 0.03 1.05 0 5.00
175 INT328369 Ghrl Negative_regulation of CRH 1 0.16 0.15 0 5.00
176 INT334921 GNRHR Positive_regulation of Gene_expression of CGA 1 0.01 0.53 0 5.00
177 INT324312 Binding of GATM and UMOD 1 0.02 1.62 0 5.00
178 INT213606 CLOCK Regulation of Gene_expression of PROK2 1 0.20 0.3 0 5.00
179 INT305273 Binding of Lep and Leprot 1 0.06 0.92 0 5.00
180 INT324306 Binding of GATM and STC1 1 0.02 1.61 0 5.00
181 INT313871 Pde5a Positive_regulation of Pah 1 0.49 0.97 0 5.00
182 INT305281 Obsty1 Regulation of Localization of Gopc 1 0.02 1.49 0 5.00
183 INT336480 Binding of Pln and RLS 1 0.02 0.34 0 5.00
184 INT305256 Binding of Car2 and Lipo2 1 0.01 0.89 0 5.00
185 INT305265 Obsty1 Negative_regulation of Phosphorylation of Nos3 1 0.05 0.78 0 5.00
186 INT334922 GNRHR Positive_regulation of Gene_expression of PLOD1 1 0.08 0.53 0 5.00
187 INT334919 GNRH1 Positive_regulation of Gene_expression of CGA 1 0.03 0.52 0 5.00
188 INT305278 Lep Negative_regulation of Obsty1 1 0.07 0.94 0 5.00
189 INT324346 Regulation of UMOD Positive_regulation of Scr 1 0.10 1.31 0 5.00
190 INT305276 Obsty1 Regulation of Phosphorylation of Mapk1 1 0.02 1.11 0 5.00
191 INT217107 Negative_regulation of Egr2 Regulation of Hoxa2 1 0.48 0 0 5.00
192 INT308706 Binding of AQP4 and M1 1 0.06 0.86 0 5.00
193 INT324343 SLC12A1 Regulation of Scr 1 0.00 0.25 0 5.00
194 INT223283 Binding of CYP2C9 and VKORC1 1 0.31 0.16 0 5.00
195 INT221910 Binding of SRI and COPD 1 0.01 1.27 0 5.00
196 INT305255 Obsty1 Positive_regulation of Phosphorylation of Akt1 1 0.05 2.09 0 5.00
197 INT305254 Obsty1 Regulation of Gene_expression of Nos3 1 0.03 0.97 0 5.00
198 INT336574 Binding of CD40LG and HCRTR1 1 0.05 0.1 0 5.00
199 INT305272 Gene_expression of Lep Positive_regulation of Positive_regulation of Stat3 1 0.40 0.46 0 5.00
200 INT305264 Positive_regulation of Binding of Lep and Leprot 1 0.08 0.93 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Apnoea. They are ordered first by their pain relevance and then by number of times they were reported in Apnoea. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT154104 Binding of ARID1B 47 0.39 69.82 1.49 100.00
2 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 100.00
3 INT267698 Gene_expression of ARID1B 18 0.63 20.47 0.47 100.00
4 INT249049 Positive_regulation of ARID1B 14 0.56 24.77 0.71 100.00
5 INT70970 Binding of COPD 144 0.42 180.34 18.29 100.00
6 INT267703 Regulation of ARID1B 6 0.21 6.85 0.45 100.00
7 INT154102 Negative_regulation of ARID1B 5 0.35 6.45 0.1 100.00
8 INT14572 Binding of INS 205 0.48 175.43 13.38 100.00
9 INT296875 Positive_regulation of AHI1 2 0.15 3.53 0.16 100.00
10 INT177683 Negative_regulation of Gene_expression of CENPJ 5 0.32 4.27 0.03 100.00
11 INT234289 Binding of Swd1 1 0.03 5.79 0.23 100.00
12 INT309863 Positive_regulation of Gene_expression of ARID1B 3 0.40 2.03 0.05 100.00
13 INT219695 Positive_regulation of Gene_expression of COPD 24 0.40 33.04 3.42 100.00
14 INT44879 Positive_regulation of TSC22D3 2 0.38 0.8 0.17 100.00
15 INT309865 Negative_regulation of Binding of ARID1B 1 0.34 1.49 0 100.00
16 INT20611 Gene_expression of Asap1 55 0.65 23.71 14.62 100.00
17 INT242321 Negative_regulation of Gene_expression of Asap1 1 0.20 1.96 0 100.00
18 INT154103 Positive_regulation of Negative_regulation of ARID1B 1 0.42 1.03 0 100.00
19 INT341638 Binding of Arid1a 2 0.09 4.25 0.04 100.00
20 INT267705 Protein_catabolism of ARID1B 2 0.71 3.18 0 100.00
21 INT158397 Binding of ARID1A 4 0.29 1.11 0.38 100.00
22 INT345953 Negative_regulation of Ahi1 1 0.08 4.67 0 100.00
23 INT318165 Regulation of Regulation of ARID1B 1 0.21 0.41 0 100.00
24 INT251515 Positive_regulation of Gene_expression of REM1 5 0.18 0.99 1.06 100.00
25 INT92941 Binding of ASAP1 24 0.39 12.38 1.25 100.00
26 INT100051 Binding of MUC5AC 20 0.32 14.21 1.14 100.00
27 INT163592 Localization of CISH 5 0.54 5.9 1.26 100.00
28 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 99.98
29 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32 99.98
30 INT24805 Gene_expression of Sstr1 4 0.37 1 4.06 99.98
31 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.96
32 INT217102 Gene_expression of Egr2 50 0.78 10.91 3.89 99.96
33 INT12231 Positive_regulation of Localization of Nts 17 0.70 4.54 13.85 99.96
34 INT117117 Positive_regulation of REM1 12 0.40 10.1 3.33 99.96
35 INT18193 Positive_regulation of Sstr1 6 0.31 1.82 4.8 99.96
36 INT812 Localization of INS 1026 0.81 515.6 145.31 99.92
37 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 99.90
38 INT176618 Gene_expression of HEY1 29 0.59 36 4.37 99.90
39 INT35349 Gene_expression of CENPJ 52 0.57 25.36 2.54 99.88
40 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22 99.84
41 INT161574 Localization of CENPJ 7 0.73 6.11 1.54 99.84
42 INT156533 Transcription of LEP 9 0.69 4.35 0.74 99.84
43 INT38987 Protein_catabolism of INS 21 0.99 11.92 2.91 99.84
44 INT217089 Regulation of Gene_expression of Hoxa2 1 0.45 0.66 0 99.82
45 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77 99.80
46 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31 99.80
47 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 99.80
48 INT350958 Positive_regulation of PSG9 1 0.07 1.56 0.07 99.80
49 INT345954 Negative_regulation of Positive_regulation of Nr2e1 1 0.07 0.9 0 99.80
50 INT27813 Regulation of CENPJ 12 0.29 14.26 0.99 99.76
51 INT90777 Gene_expression of Kcnn3 39 0.77 10.35 6.35 99.76
52 INT90778 Regulation of Gene_expression of Kcnn3 2 0.61 1.56 0.37 99.76
53 INT8363 Localization of Nts 135 0.81 14.29 61.71 99.68
54 INT217100 Negative_regulation of Gene_expression of Egr2 1 0.57 0.44 0.12 99.68
55 INT75908 Regulation of LEP 77 0.60 60.16 15.19 99.64
56 INT263329 Localization of CNBP 1 0.01 1.59 0 99.64
57 INT186450 Negative_regulation of SFTPB 17 0.58 10.94 0.31 99.52
58 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.44
59 INT217098 Gene_expression of Hoxa2 1 0.77 2.23 0.72 99.42
60 INT345962 Positive_regulation of Ahi1 1 0.10 4.11 0 99.40
61 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.28
62 INT296873 Binding of Sxbq1 1 0.09 3.24 0.43 99.28
63 INT4395 Positive_regulation of CSH1 20 0.50 6.27 1.52 99.12
64 INT1530 Regulation of Gh 382 0.61 115.96 112.47 99.08
65 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 99.06
66 INT296871 Positive_regulation of Sxbq1 1 0.10 1.63 0.24 99.04
67 INT44880 Gene_expression of REM1 21 0.30 5.3 2.43 99.00
68 INT177643 Binding of CENPJ 12 0.36 8.59 0.22 98.96
69 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 98.96
70 INT62568 Positive_regulation of Positive_regulation of Crp 9 0.68 8.61 2.98 98.96
71 INT60436 Negative_regulation of COPD 76 0.37 84.22 9.08 98.92
72 INT259580 Negative_regulation of Binding of COPD 2 0.10 3.44 0.17 98.92
73 INT345959 Positive_regulation of Nr2e1 1 0.12 0.9 0 98.88
74 INT88868 Binding of MCS 45 0.40 37.43 7.98 98.84
75 INT1682 Negative_regulation of Rem1 28 0.37 7.38 8.4 98.72
76 INT58770 Gene_expression of MSSE 9 0.56 5.75 0.08 98.72
77 INT1124 Negative_regulation of CD40LG 53 0.57 36.26 7 98.66
78 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 98.56
79 INT101673 Regulation of Regulation of Ggh 2 0.24 0.25 0.97 98.48
80 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 98.28
81 INT187286 Binding of HEY1 17 0.32 31.21 4.52 98.24
82 INT92343 Negative_regulation of CENPJ 20 0.57 6.25 0.2 98.24
83 INT10173 Binding of Tnf 45 0.48 35.6 14.32 98.22
84 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 98.04
85 INT334924 Binding of MEHMO 1 0.01 9.69 0.26 97.96
86 INT217096 Negative_regulation of Egr2 10 0.58 3.23 0.24 97.92
87 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 97.56
88 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 97.56
89 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 97.52
90 INT305242 Binding of Obsty1 1 0.07 9.33 0.17 97.24
91 INT111451 Regulation of ADIPOQ 24 0.56 18.81 2.47 96.80
92 INT327816 Regulation of Positive_regulation of ADIPOQ 1 0.04 1.2 0.09 96.80
93 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67 96.80
94 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 96.76
95 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17 96.64
96 INT148883 Gene_expression of HCRTR1 8 0.36 24.82 1.35 96.56
97 INT296870 Localization of Sxbq1 1 0.15 1.4 0.04 96.40
98 INT1703 Regulation of PCa 52 0.52 23.65 20.6 96.36
99 INT12455 Negative_regulation of Adra2a 30 0.54 5.63 10.14 96.08
100 INT111385 Negative_regulation of Adora3 7 0.43 3.91 2.8 95.80
101 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52 95.76
102 INT1893 Localization of Gh 1041 0.79 340.23 256.58 95.72
103 INT126685 Gene_expression of Rem1 30 0.65 11.21 3.61 95.44
104 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 95.40
105 INT12082 Localization of IL6 365 0.81 241.78 105.78 95.32
106 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 95.28
107 INT8361 Regulation of Localization of Nts 9 0.46 0.54 3.39 95.24
108 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 95.24
109 INT59286 Regulation of Gene_expression of EPO 7 0.62 6.13 0.13 95.24
110 INT16153 Gene_expression of Cenpj 7 0.77 2.56 1.42 95.16
111 INT345958 Negative_regulation of Gene_expression of Cenpj 1 0.20 0.91 0 95.16
112 INT163581 Localization of Lep 27 0.79 18.99 4.08 95.12
113 INT263328 Positive_regulation of KIF20B 1 0.28 2.56 0.04 95.12
114 INT117855 Negative_regulation of Ghrl 29 0.57 17.52 5 94.88
115 INT61784 Positive_regulation of CENPJ 27 0.51 11.46 2.28 94.84
116 INT56310 Gene_expression of Baat 15 0.44 15.5 1.11 94.84
117 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 94.84
118 INT4530 Regulation of Ggh 9 0.54 2.5 3.96 94.84
119 INT50437 Regulation of LIF 6 0.44 2.12 1.53 94.84
120 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 94.84
121 INT125578 Positive_regulation of Localization of IGF1 6 0.60 7.59 0.53 94.84
122 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 94.72
123 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 94.72
124 INT66332 Gene_expression of Ucp1 40 0.75 40.09 2.48 94.68
125 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 94.56
126 INT263327 Positive_regulation of Positive_regulation of NFKB2 2 0.08 2.95 0.42 94.40
127 INT91463 Positive_regulation of NFKB2 19 0.40 17.7 4.6 94.40
128 INT336028 Regulation of Tpcn1 2 0.03 4.32 0 94.32
129 INT1864 Regulation of Bche 18 0.47 6.18 2.44 94.28
130 INT161812 Positive_regulation of PER1 17 0.56 5.64 2.93 94.28
131 INT34777 Localization of IGF1 82 0.80 42.68 8.62 94.28
132 INT20612 Positive_regulation of Asap1 36 0.68 24.35 6.06 94.04
133 INT148384 Positive_regulation of HEY1 19 0.43 29.76 5.89 93.84
134 INT19 Regulation of Gnrhr 131 0.62 36.4 55.66 93.76
135 INT133112 Regulation of Baat 2 0.61 11.99 1.2 93.64
136 INT1499 Negative_regulation of Gene_expression of Gh 58 0.42 25.17 7.86 93.56
137 INT177642 Positive_regulation of Gene_expression of CENPJ 5 0.30 3.25 0.07 93.52
138 INT251 Regulation of INS 398 0.62 232.47 55.04 93.46
139 INT28325 Negative_regulation of Tst 13 0.51 12.41 3.16 93.44
140 INT73427 Localization of P2rx7 24 0.79 8.65 9.87 93.36
141 INT5148 Regulation of CD40LG 25 0.44 21.58 4.05 93.30
142 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51 93.28
143 INT38989 Gene_expression of IDUA 22 0.78 16.99 1.26 93.24
144 INT10166 Localization of Tnf 237 0.81 153.95 88.64 93.16
145 INT175895 Negative_regulation of KRT1 5 0.37 3.23 0.05 93.08
146 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32 92.72
147 INT191289 Positive_regulation of Psrs1 1 0.01 0.43 0 92.64
148 INT5307 Regulation of Tnf 87 0.62 78.71 43.4 92.44
149 INT94608 Regulation of P2rx7 19 0.23 8.06 6.19 92.40
150 INT50403 Negative_regulation of CYP2C19 55 0.59 8.97 17.79 92.12
151 INT284977 Binding of DNMT1 3 0.17 0.86 0 92.00
152 INT169747 Localization of AQP4 17 0.75 16.64 2.79 92.00
153 INT223091 Gene_expression of ELF3 45 0.62 17.9 1.56 91.88
154 INT245115 Positive_regulation of Gene_expression of ELF3 8 0.40 2.23 0.06 91.88
155 INT217097 Regulation of Egr2 3 0.62 1.4 0.29 91.80
156 INT54763 Binding of Il6 82 0.48 63.27 12.89 91.68
157 INT18934 Gene_expression of GER 16 0.66 14.71 1.29 91.44
158 INT403 Localization of Trh 241 0.81 28.55 81.45 91.44
159 INT202052 Negative_regulation of URB1 2 0.04 2.16 0.85 91.40
160 INT281803 Regulation of Ucp1 4 0.57 4.03 0.05 90.92
161 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 90.64
162 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 90.56
163 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 90.56
164 INT54924 Gene_expression of RLS 67 0.62 83.2 14.25 90.32
165 INT75907 Binding of LEP 53 0.46 46.65 8.44 90.08
166 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 90.04
167 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 90.04
168 INT9677 Negative_regulation of Gene_expression of GH1 46 0.48 23.32 3.68 90.04
169 INT331017 Transcription of MAMLD1 1 0.67 0.4 0 90.04
170 INT138216 Negative_regulation of PER1 13 0.37 9.66 4.55 89.92
171 INT45219 Positive_regulation of Phmr 3 0.30 0.48 0.81 89.60
172 INT18340 Gene_expression of CRX 16 0.22 13.85 7.13 89.52
173 INT11729 Regulation of IGF1 71 0.61 44.58 9.71 89.48
174 INT81972 Positive_regulation of Dse 20 0.57 16.5 2.99 89.12
175 INT147793 Localization of COPD 70 0.64 89.01 7.3 89.04
176 INT104324 Negative_regulation of Baat 4 0.38 9.79 0.42 88.96
177 INT24816 Binding of CD40LG 68 0.47 45.48 11.56 88.60
178 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 88.56
179 INT2659 Positive_regulation of Psgb1 2 0.40 3.25 0.3 88.48
180 INT157932 Positive_regulation of ADHD1 46 0.48 52.18 6.13 88.40
181 INT217685 Negative_regulation of BMI1 7 0.18 6.01 0.82 88.24
182 INT45597 Negative_regulation of Epo 22 0.59 12.47 2.35 88.16
183 INT350956 Binding of Psgb1 1 0.03 1.64 0.08 87.92
184 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 87.92
185 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 87.88
186 INT111401 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 134 0.61 34.87 20.15 87.88
187 INT163359 Gene_expression of RFC1 9 0.65 3.34 2.64 87.68
188 INT40476 Negative_regulation of RFC1 5 0.18 2.85 0.72 87.68
189 INT182074 Negative_regulation of Gene_expression of RFC1 1 0.03 0.76 0.08 87.68
190 INT259697 Regulation of MSSE 6 0.14 3 0.23 87.56
191 INT177537 Negative_regulation of CSF3R 1 0.17 1.64 0.05 87.48
192 INT56309 Positive_regulation of Baat 9 0.39 8.47 1.51 87.36
193 INT1705 Gene_expression of pCA 126 0.65 88.65 34.81 87.20
194 INT117585 Regulation of Hcrt 10 0.56 6.16 1.77 87.04
195 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 86.64
196 INT217091 Positive_regulation of Rrm2 5 0.33 4.12 0.6 86.60
197 INT143789 Positive_regulation of PEG10 2 0.40 0.25 0.17 86.52
198 INT53906 Positive_regulation of Negative_regulation of Gh 9 0.50 6.72 2.73 86.20
199 INT200200 Positive_regulation of Negative_regulation of Igf1 3 0.47 2.33 0.22 86.20
200 INT115877 Negative_regulation of Adcyap1 14 0.59 5.31 3.74 86.16
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