D:Apoptosis

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Disease Term
Synonyms Apoptotic, GENE DIRECTED CELL DEATH, PROGRAMMED CELL DEATH, Type I Programmed Cell Death
Documents 5654
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Apoptosis. They are ordered first by their relevance to Apoptosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT282995 Binding of Bcl2 and Becn1 21 0.03 9.8 0 100.00
2 INT172901 Binding of Bad and Bcl2l1 3 0.13 6.51 0.27 100.00
3 INT172905 Binding of Bad and Bcl2 3 0.08 6.46 0.27 100.00
4 INT172213 Binding of BAX and BCL2L1 3 0.22 4.02 0.35 100.00
5 INT198011 Binding of BAX and MCL1 2 0.20 3.04 0 100.00
6 INT198015 Binding of BAK1 and MCL1 1 0.26 5.16 0 100.00
7 INT194595 Binding of TNFSF10 and TNFRSF10B 4 0.15 9.3 0.53 100.00
8 INT185852 Binding of BAK1 and BAX 3 0.29 2.5 0 100.00
9 INT178861 Binding of BAX and BCL2 3 0.27 3.07 0 100.00
10 INT275758 Binding of xn and Igfbp3 1 0.03 5.39 0.04 100.00
11 INT176224 Binding of CDKN1A and PCNA 4 0.08 2.52 0.03 100.00
12 INT237922 TNFSF10 Positive_regulation of CDKN1A 1 0.09 3.28 0.08 100.00
13 INT194596 Binding of HLA-DRB4 and TNFSF10 3 0.08 6 0.38 100.00
14 INT198021 Binding of BCL2 and MCL1 1 0.17 2.88 0 100.00
15 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29 100.00
16 INT185856 Binding of BAD and BCL2L1 4 0.39 2.73 0 100.00
17 INT333688 Trp53 Positive_regulation of Bcl2 1 0.45 2.51 0 100.00
18 INT275746 Binding of xn and Bax 1 0.05 2.57 0 100.00
19 INT155061 Stat3 Negative_regulation of Bax 1 0.22 3.71 0.34 100.00
20 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33 100.00
21 INT155058 Stat3 Negative_regulation of Akp3 1 0.01 3.7 0.33 100.00
22 INT155064 Stat3 Negative_regulation of Tp53bp2 1 0.06 3.69 0.33 100.00
23 INT148103 MAPK8 Positive_regulation of STK24 1 0.47 1.82 0.17 100.00
24 INT189992 Binding of Ptger2 and Pawr 1 0.00 2.89 0 100.00
25 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23 100.00
26 INT349532 Positive_regulation of Binding of Smcp and Tnfsf10 1 0.35 2.16 0 100.00
27 INT295920 Mir761 Positive_regulation of Transcription of Bcl2l1 1 0.00 1.43 0 100.00
28 INT302149 Binding of BCL2L1 and MCL1 1 0.03 1.1 0 100.00
29 INT108546 BCL2L10 Regulation of MAPKAPK5 1 0.03 1.22 1.1 100.00
30 INT198005 Binding of BID and MCL1 1 0.24 2.04 0 100.00
31 INT345171 Binding of Trip6 and Magi3 1 0.03 1.65 0.14 100.00
32 INT220445 Bcl2 Negative_regulation of Positive_regulation of Casp9 1 0.01 1.37 0.03 100.00
33 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34 100.00
34 INT345146 Binding of Trip6 and Siva1 1 0.02 1.6 0.14 100.00
35 INT135947 MCC Regulation of GDF15 1 0.11 1.58 0.27 100.00
36 INT302169 PTGER2 Positive_regulation of DYNC1LI1 1 0.02 1.51 0.25 100.00
37 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74 100.00
38 INT292454 Binding of BAD and BCL2 2 0.03 1.73 0 100.00
39 INT349537 Smcp Positive_regulation of Tnfsf10 1 0.38 3.48 0.28 100.00
40 INT172908 Binding of Bad and Bax 1 0.01 1.34 0 100.00
41 INT333693 Hr Negative_regulation of Gene_expression of Trp53 1 0.27 0.9 0 100.00
42 INT275759 Binding of xn and Ins1 1 0.01 1.95 0 100.00
43 INT204300 Bcl2 Negative_regulation of Positive_regulation of Bak1 1 0.02 1.13 0.09 100.00
44 INT204299 Bcl2 Negative_regulation of Localization of Aifm1 1 0.06 1.22 0.07 100.00
45 INT333695 Trp53 Positive_regulation of Localization of Bcl2l1 1 0.23 1.33 0 100.00
46 INT333691 Trp53 Positive_regulation of Bcl2l1 1 0.23 1.33 0 100.00
47 INT150391 Binding of MEFV and PYCARD 4 0.14 3 0.48 100.00
48 INT302161 AKT1 Negative_regulation of CASP9 1 0.03 0.87 0.11 100.00
49 INT335715 Binding of FASLG and CD4 1 0.22 0.9 0.06 100.00
50 INT335714 Binding of FAS and CD4 1 0.38 0.9 0.06 100.00
51 INT335712 Binding of FASLG and CD8A 1 0.18 0.9 0.06 100.00
52 INT335713 Binding of FAS and CD8A 1 0.32 0.9 0.06 100.00
53 INT130922 HMHA1 Positive_regulation of Protein_catabolism of CYCS 1 0.06 1.39 0.14 100.00
54 INT130917 HMHA1 Positive_regulation of CYCS 1 0.06 1.39 0.14 100.00
55 INT130918 HMHA1 Positive_regulation of BAX 1 0.04 1.37 0.14 100.00
56 INT130923 HMHA1 Positive_regulation of Protein_catabolism of CASP8 1 0.04 1.37 0.14 100.00
57 INT130919 HMHA1 Positive_regulation of Protein_catabolism of CASP9 1 0.03 1.37 0.14 100.00
58 INT130921 HMHA1 Positive_regulation of CASP9 1 0.03 1.37 0.14 100.00
59 INT323705 Binding of FAS and FAF1 1 0.42 1.46 0 100.00
60 INT130920 HMHA1 Positive_regulation of CASP8 1 0.04 1.36 0.14 100.00
61 INT330056 Bcl2 Regulation of Localization of Cyct 1 0.27 0.97 0 100.00
62 INT253762 Binding of Apex1 and Hmgb1 1 0.09 1.29 0.32 100.00
63 INT333687 Trp53 Positive_regulation of Localization of Bcl2 1 0.45 1.24 0 100.00
64 INT232898 Binding of KRT1 and Krt8 1 0.27 1.22 0 100.00
65 INT275760 Binding of Igfbp3 and xn 1 0.00 1.32 0 100.00
66 INT155066 Csf2 Negative_regulation of Bax 1 0.12 1.89 0.17 100.00
67 INT155068 Csf2 Negative_regulation of Bcl2 1 0.12 1.88 0.17 100.00
68 INT155059 Csf2 Negative_regulation of Akp3 1 0.00 1.88 0.17 100.00
69 INT155065 Csf2 Negative_regulation of Tp53bp2 1 0.03 1.88 0.17 100.00
70 INT203044 Binding of PDCD1 and DTHD1 1 0.02 3.19 1.87 100.00
71 INT218937 Akt1 Positive_regulation of Parn 1 0.01 0.65 0.16 100.00
72 INT218930 Akt1 Positive_regulation of Xiap 1 0.06 0.64 0.16 100.00
73 INT336891 Epo Negative_regulation of Transcription of Bax 1 0.10 0.68 0.16 100.00
74 INT327404 Binding of Xiap and Siva1 1 0.02 1.97 0.03 100.00
75 INT198023 Binding of BAK1 and BID 1 0.12 0.82 0 100.00
76 INT198014 Binding of MCL1 and BCL2L11 1 0.11 0.82 0 100.00
77 INT234382 Binding of TNF and TNFSF10 1 0.11 1.2 0.04 100.00
78 INT234383 Positive_regulation of Binding of TNF and TNFSF10 1 0.15 1.2 0.04 100.00
79 INT198007 MTOR Regulation of Gene_expression of GOPC 1 0.08 1.33 0 100.00
80 INT148806 Diablo Positive_regulation of Positive_regulation of Casp3 1 0.03 1.02 0.89 100.00
81 INT304135 Binding of CEL and Positive_regulation of CASP8 1 0.00 0.52 0 100.00
82 INT279965 STAT3 Regulation of Transcription of BCL2L1 1 0.10 2.31 0.19 100.00
83 INT341375 Sod2 Regulation of Bcl2 1 0.08 1.96 0.05 100.00
84 INT315061 PAR4 Positive_regulation of Gene_expression of TNF 1 0.10 1.95 0 100.00
85 INT345486 PMAIP1 Positive_regulation of Localization of CYC1 1 0.18 0.96 0 100.00
86 INT197999 Binding of BCL2 and MCL1 Negative_regulation of C12orf65 1 0.00 1.21 0 100.00
87 INT191693 Igh-Dex Regulation of Bag1 Regulation of gr 1 0.01 1.31 0.21 100.00
88 INT213005 Hdl1 Positive_regulation of Akt1 3 0.19 3.81 0.14 100.00
89 INT262522 Binding of Trp53 and Foxo4 1 0.05 0.7 0.1 100.00
90 INT182273 EDN1 Regulation of Gene_expression of BAD 1 0.11 0.73 0.12 100.00
91 INT294637 Bcl2a1a Positive_regulation of Gene_expression of Bcl2 1 0.15 0.97 0.09 100.00
92 INT302172 Binding of BAD and BAX 1 0.06 0.93 0 100.00
93 INT302137 Binding of BAD and BAK1 1 0.07 0.93 0 100.00
94 INT302132 Negative_regulation of Binding of BAD and BAK1 1 0.06 0.93 0 100.00
95 INT317319 Binding of Trap1 and Pink1 1 0.26 2.67 0 100.00
96 INT218928 Cyp3a23/3a1 Regulation of Transcription of Bcl2 1 0.00 0.56 0.28 100.00
97 INT201736 Nfkb1 Positive_regulation of Transcription of Sod2 1 0.01 0.93 0.08 100.00
98 INT322560 Binding of TNFSF10 and DICER1 1 0.07 1.76 0.07 100.00
99 INT116610 Positive_regulation of Lnpep Regulation of Nos2 1 0.16 0.62 0.44 100.00
100 INT268665 Ptger2 Positive_regulation of Gene_expression of Mcl1 1 0.03 0.9 0.04 100.00
101 INT116608 Lnpep Regulation of Nos2 1 0.14 0.62 0.44 100.00
102 INT268664 Ptger2 Positive_regulation of Bcl2 1 0.02 0.9 0.04 100.00
103 INT268666 Ptger2 Positive_regulation of Gene_expression of Bcl2 1 0.02 0.9 0.04 100.00
104 INT134401 Negative_regulation of MAPK3 Negative_regulation of Gene_expression of ARMC3 1 0.19 1.16 0.13 100.00
105 INT265891 IGF1 Regulation of AKT1 1 0.05 1.24 0.03 100.00
106 INT265884 IGF1 Regulation of CREB1 1 0.13 1.31 0.03 100.00
107 INT265879 IGF1 Regulation of FOXO1 1 0.11 1.37 0.03 100.00
108 INT265880 IGF1 Regulation of PIK3CG 1 0.10 1.23 0.03 100.00
109 INT265906 IGF1 Regulation of Gsk3b 1 0.25 1.31 0.03 100.00
110 INT254707 Positive_regulation of Map2k1 Regulation of Gene_expression of BAK1 1 0.05 0.67 0 100.00
111 INT116611 Lnpep Positive_regulation of Binding of Nos2 1 0.16 0.62 0.42 100.00
112 INT113218 TNFRSF25 Positive_regulation of Localization of CYCS 1 0.18 0.74 0.07 100.00
113 INT254089 EPO Regulation of Gene_expression of Bcl2 1 0.03 0.63 0 100.00
114 INT134399 Negative_regulation of MAPK3 Positive_regulation of Phosphorylation of MAPK8 1 0.39 1.14 0.13 100.00
115 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67 100.00
116 INT254090 EPO Negative_regulation of Gene_expression of Bax 1 0.10 0.63 0 100.00
117 INT110758 Tnfaip8 Positive_regulation of Positive_regulation of Nos2 1 0.14 0.88 0.34 100.00
118 INT110761 Tnfaip8 Positive_regulation of Nos2 1 0.13 0.88 0.34 100.00
119 INT327969 Binding of PNLIP and TNFRSF11A 1 0.09 0.89 0 100.00
120 INT221240 Akt1 Positive_regulation of Phosphorylation of Bcl2 1 0.00 0.89 0 100.00
121 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22 100.00
122 INT221252 Akt1 Negative_regulation of Localization of CYC1 1 0.15 0.9 0 100.00
123 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22 100.00
124 INT289997 CNTF Negative_regulation of Binding of CNTF and Casp3 1 0.05 0.99 0.22 100.00
125 INT289999 Binding of CNTF and Casp3 1 0.04 0.99 0.22 100.00
126 INT317836 Binding of Fibp and Pycard 1 0.00 2.68 0.98 100.00
127 INT302131 Negative_regulation of SOD2 Regulation of BAK1 1 0.09 1.22 0.07 100.00
128 INT302289 Negative_regulation of Birc5 Regulation of BAK1 1 0.20 1.22 0.07 100.00
129 INT302290 Birc5 Regulation of BAK1 1 0.21 1.22 0.07 100.00
130 INT302128 SOD2 Regulation of BAK1 1 0.09 1.22 0.07 100.00
131 INT201769 Akt1 Negative_regulation of Phosphorylation of CASP9 1 0.00 0.82 0 100.00
132 INT85119 CSF2 Regulation of CDCP1 1 0.01 0.66 0.31 100.00
133 INT85124 IL5 Regulation of CDCP1 1 0.01 0.66 0.31 100.00
134 INT85120 IL3 Regulation of Gene_expression of CDCP1 1 0.01 0.66 0.31 100.00
135 INT85118 CSF2 Regulation of Gene_expression of CDCP1 1 0.00 0.66 0.31 100.00
136 INT85123 IL5 Regulation of Gene_expression of CDCP1 1 0.01 0.66 0.31 100.00
137 INT85117 IL3 Regulation of CDCP1 1 0.01 0.66 0.31 100.00
138 INT130690 Gene_expression of HSPA5 Negative_regulation of Positive_regulation of DDIT3 1 0.21 0.58 0.17 100.00
139 INT268459 Binding of LDLR and Olr1 1 0.00 0.78 0 100.00
140 INT217150 MIR16-2 Regulation of BCL2 2 0.09 1.89 0 100.00
141 INT217137 MIR15B Regulation of BCL2 2 0.15 1.88 0 100.00
142 INT340394 Binding of Bax and Bbc3 1 0.01 0.36 0.04 100.00
143 INT166732 BATF Negative_regulation of PPIA 1 0.05 1.45 0.06 100.00
144 INT166734 BATF Negative_regulation of PPIL1 1 0.04 1.45 0.06 100.00
145 INT117913 CREM Positive_regulation of Negative_regulation of BIRC2 1 0.15 0.81 0.14 100.00
146 INT223826 GSTM1 Negative_regulation of MAP3K5 1 0.02 0.71 0.03 100.00
147 INT200647 HDAC4 Positive_regulation of CASP9 1 0.10 0.93 0 100.00
148 INT200644 HDAC4 Positive_regulation of CASP8 1 0.07 0.92 0 100.00
149 INT97517 Binding of PYCARD and Mefv 1 0.07 0.78 0.14 100.00
150 INT97515 Binding of Mefv and Pycard 1 0.00 0.78 0.14 100.00
151 INT323708 Binding of CASP8 and FAF1 1 0.07 0.73 0 100.00
152 INT243118 amd Regulation of Rpe 1 0.20 1.16 0 100.00
153 INT265888 BCL2 Regulation of Gene_expression of BAD 1 0.04 1.08 0.1 100.00
154 INT265890 BCL2 Regulation of Gene_expression of BAX 1 0.04 1.08 0.1 100.00
155 INT265889 BAX Regulation of Gene_expression of BAD 1 0.06 1.08 0.1 100.00
156 INT260438 Binding of Cd4 and Mx1 1 0.00 1.52 0.29 100.00
157 INT260434 Binding of Cd8a and Mx1 1 0.00 1.52 0.29 100.00
158 INT176340 CHI3L1 Positive_regulation of Localization of CSF2 1 0.11 1.86 0.55 100.00
159 INT176343 CHI3L1 Positive_regulation of Localization of CSF1 1 0.23 1.86 0.55 100.00
160 INT176342 CSF1 Positive_regulation of Localization of CSF2 1 0.26 1.84 0.54 100.00
161 INT177915 EGF Positive_regulation of Phosphorylation of AKT1 1 0.03 0.51 0 100.00
162 INT218932 Cyp3a23/3a1 Regulation of Gene_expression of Alpi 1 0.00 0.53 0.46 100.00
163 INT206853 ESR1 Positive_regulation of Gene_expression of PCP4 1 0.08 1.39 0.04 100.00
164 INT206847 ESR1 Negative_regulation of Gene_expression of PTGER3 1 0.08 1.52 0.04 100.00
165 INT140607 PMEL Positive_regulation of Gene_expression of DDIT3 1 0.01 0.75 0 100.00
166 INT193960 Binding of Bcl2l1 and Ps 1 0.01 0.6 0 100.00
167 INT186989 Binding of Akt1 and Tert 1 0.00 0.61 0 100.00
168 INT193965 Binding of BCL2 and Ps 1 0.05 0.59 0 100.00
169 INT98555 Oprm1 Positive_regulation of Casp8 1 0.51 0.36 1.02 100.00
170 INT98556 Oprm1 Positive_regulation of Casp3 1 0.38 0.36 1.01 100.00
171 INT226741 Mela Positive_regulation of Gene_expression of Cd4 1 0.02 1.01 0 100.00
172 INT226747 Mela Positive_regulation of Gene_expression of Cxcr4 1 0.03 1.01 0 100.00
173 INT81631 Selenbp2 Negative_regulation of Fas 1 0.03 0.77 0.67 100.00
174 INT81630 Selenbp2 Negative_regulation of Positive_regulation of Fas 1 0.03 0.77 0.67 100.00
175 INT313426 Positive_regulation of Ppp2ca Positive_regulation of Bax 1 0.46 0.36 0 100.00
176 INT115142 TGM7 Positive_regulation of Gene_expression of CITED2 1 0.02 0.45 0.2 100.00
177 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 0.05 0.75 0.28 100.00
178 INT280164 Twist1 Negative_regulation of Mod2 1 0.06 1.76 0 100.00
179 INT341376 Sod2 Regulation of Bax 1 0.09 0.99 0.03 100.00
180 INT355018 Binding of FAS and Faslg 1 0.12 1.34 0.37 100.00
181 INT150389 Binding of GFRA1 and MEFV 1 0.02 0.85 0.12 100.00
182 INT150387 Binding of MEFV and TNF 1 0.31 0.85 0.12 100.00
183 INT150390 Binding of CD27 and MEFV 1 0.27 0.85 0.12 100.00
184 INT273063 Negative_regulation of Fas Negative_regulation of Positive_regulation of Bcl2 1 0.01 0.72 0.11 100.00
185 INT123461 Binding of TNFSF10 and Tnfrsf11b 1 0.00 1.34 0.08 100.00
186 INT322672 Binding of SLC25A6 and Pbrm1 1 0.04 1.87 0.03 100.00
187 INT323698 Gene_expression of MIR146A Regulation of FAF1 1 0.16 1.82 0.86 100.00
188 INT220634 Binding of Bace1 and Pawr 2 0.06 0.2 0 100.00
189 INT348022 Binding of Jun and Trp53 1 0.07 0.46 0.04 100.00
190 INT302147 PTGER2 Positive_regulation of BAK1 1 0.06 2.08 0.06 100.00
191 INT302177 PTGER2 Positive_regulation of BCL2 1 0.04 2.08 0.06 100.00
192 INT302138 PTGER2 Positive_regulation of Gene_expression of BAK1 1 0.06 2.08 0.06 100.00
193 INT101067 MAP3K15 Positive_regulation of MAPK1 1 0.21 0.47 1.03 100.00
194 INT101066 MAP3K15 Positive_regulation of CDCP1 1 0.03 0.46 1.03 100.00
195 INT351682 Fut1 Positive_regulation of PTEN 1 0.01 1.81 0 100.00
196 INT247638 Atf3 Positive_regulation of Hspb2 1 0.01 1 0 100.00
197 INT101065 MAP3K15 Positive_regulation of JUN 1 0.43 0.46 1.02 100.00
198 INT247640 Atf3 Positive_regulation of Gtf3a 1 0.01 0.99 0 100.00
199 INT182367 IgG Regulation of Vim 1 0.00 0.99 0.11 100.00
200 INT186096 EGF Regulation of Positive_regulation of CASP3 1 0.01 0.28 0 100.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Apoptosis. They are ordered first by their pain relevance and then by number of times they were reported in Apoptosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 100.00
2 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 100.00
3 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 100.00
4 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38 100.00
5 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94 100.00
6 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 100.00
7 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 100.00
8 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 100.00
9 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 100.00
10 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36 100.00
11 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68 100.00
12 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 100.00
13 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48 100.00
14 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01 100.00
15 INT164587 Gene_expression of MCL1 94 0.75 124.05 5.39 100.00
16 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32 100.00
17 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 100.00
18 INT108588 Gene_expression of CASP3 126 0.78 84.49 16.2 100.00
19 INT84685 Regulation of BCL2 67 0.60 72.96 6.65 100.00
20 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 100.00
21 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 100.00
22 INT83797 Gene_expression of Bcl2l1 124 0.77 94.55 22.39 100.00
23 INT98130 Positive_regulation of CASP8 79 0.67 65.29 10.08 100.00
24 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 100.00
25 INT77620 Gene_expression of Fas 146 0.78 72.4 16.61 100.00
26 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68 100.00
27 INT6481 Binding of TNF 624 0.48 510.2 214.82 100.00
28 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 100.00
29 INT73595 Positive_regulation of BAX 61 0.61 56.97 7.82 100.00
30 INT94388 Gene_expression of GDF15 124 0.77 79.48 31.42 100.00
31 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61 100.00
32 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27 100.00
33 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63 100.00
34 INT116856 Gene_expression of TNFSF10 110 0.75 115.76 21.48 100.00
35 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07 100.00
36 INT80690 Positive_regulation of MAPK8 223 0.68 125.63 36.75 100.00
37 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41 100.00
38 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11 100.00
39 INT164582 Negative_regulation of MCL1 56 0.56 67.11 2.82 100.00
40 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18 100.00
41 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59 100.00
42 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43 100.00
43 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02 100.00
44 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 100.00
45 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 100.00
46 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 100.00
47 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46 100.00
48 INT73596 Positive_regulation of Gene_expression of BAX 43 0.67 40.97 9.22 100.00
49 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 100.00
50 INT87420 Gene_expression of BCL2L1 56 0.75 48.84 5.32 100.00
51 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 100.00
52 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 100.00
53 INT256913 Gene_expression of Hr 6 0.46 35.3 0.1 100.00
54 INT94390 Positive_regulation of Gene_expression of GDF15 67 0.69 45.5 14.74 100.00
55 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06 100.00
56 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 100.00
57 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86 100.00
58 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37 100.00
59 INT81629 Positive_regulation of Fas 58 0.70 59.63 12.94 100.00
60 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92 100.00
61 INT178174 Gene_expression of Tnfsf10 78 0.76 56.83 8.64 100.00
62 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22 100.00
63 INT101988 Positive_regulation of GDF15 71 0.69 51.03 18.56 100.00
64 INT84686 Regulation of BAX 26 0.49 28.54 4.13 100.00
65 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2 100.00
66 INT108333 Phosphorylation of BAD 43 0.68 33.77 2.45 100.00
67 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41 100.00
68 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71 100.00
69 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 100.00
70 INT80037 Gene_expression of BAK1 58 0.75 39.49 9.08 100.00
71 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51 100.00
72 INT102749 Positive_regulation of Positive_regulation of CASP3 32 0.67 26.07 6.93 100.00
73 INT93620 Positive_regulation of Gene_expression of Fasl 51 0.66 59.45 12.04 100.00
74 INT80036 Positive_regulation of FAS 42 0.67 42.22 9.4 100.00
75 INT99505 Gene_expression of Bcl2l1 42 0.77 33.12 10.15 100.00
76 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78 100.00
77 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4 100.00
78 INT116464 Negative_regulation of Birc5 53 0.59 45.4 4.91 100.00
79 INT101858 Negative_regulation of BAX 25 0.57 23.77 4.16 100.00
80 INT149093 Positive_regulation of TNFSF10 31 0.49 34.61 4.56 100.00
81 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28 100.00
82 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16 100.00
83 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 100.00
84 INT116143 Positive_regulation of Casp9 32 0.67 30.34 3.04 100.00
85 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85 100.00
86 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06 100.00
87 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33 100.00
88 INT15543 Gene_expression of CASP8 32 0.75 25.6 2.61 100.00
89 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53 100.00
90 INT172855 Binding of Bcl2 37 0.32 23.41 1.09 100.00
91 INT91509 Localization of CYC1 39 0.78 34.74 7.17 100.00
92 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53 100.00
93 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 100.00
94 INT101857 Negative_regulation of BCL2L1 22 0.57 23.56 3.95 100.00
95 INT108585 Positive_regulation of Gene_expression of CASP3 35 0.70 28.37 6.45 100.00
96 INT13385 Gene_expression of Bad 60 0.76 41.86 6.52 100.00
97 INT81628 Positive_regulation of Gene_expression of Fas 32 0.67 38.13 4.23 100.00
98 INT70021 Localization of BCL2 23 0.74 21.6 1.09 100.00
99 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49 100.00
100 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7 100.00
101 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37 100.00
102 INT98554 Positive_regulation of Casp8 20 0.67 21.32 2.9 100.00
103 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7 100.00
104 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 100.00
105 INT65597 Negative_regulation of Casp3 69 0.59 39.19 29.32 100.00
106 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 100.00
107 INT204795 Gene_expression of Xiap 9 0.60 15.32 0.7 100.00
108 INT126583 Positive_regulation of PARP1 50 0.68 41.44 7.78 100.00
109 INT112692 Localization of Bax 31 0.80 20.97 3.98 100.00
110 INT150528 Positive_regulation of Gene_expression of TNFSF10 26 0.67 30.71 5.43 100.00
111 INT101641 Gene_expression of Mcl1 25 0.54 20.3 2.23 100.00
112 INT119830 Gene_expression of BAD 24 0.50 20.05 1.41 100.00
113 INT122487 Positive_regulation of Positive_regulation of CASP9 16 0.67 17.88 1.79 100.00
114 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77 100.00
115 INT60585 Regulation of TP53 59 0.59 54.55 5.21 100.00
116 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68 100.00
117 INT233561 Gene_expression of Clu 14 0.66 45.63 1.07 100.00
118 INT10992 Gene_expression of PARP1 32 0.76 22.22 3.74 100.00
119 INT70019 Binding of BCL2 25 0.47 17.55 0.79 100.00
120 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69 100.00
121 INT185872 Localization of BAK1 6 0.74 11.28 0.12 100.00
122 INT109450 Positive_regulation of Phosphorylation of AKT1 62 0.64 25.18 4.21 100.00
123 INT99942 Positive_regulation of Fasl 37 0.68 32.61 6.92 100.00
124 INT77627 Regulation of Gene_expression of BAX 14 0.44 15.09 2.12 100.00
125 INT78938 Binding of IGFBP3 40 0.45 27.95 1.73 100.00
126 INT135542 Positive_regulation of Bak1 17 0.43 16.12 0.88 100.00
127 INT29704 Regulation of Casp3 51 0.56 22.13 22.79 100.00
128 INT95423 Negative_regulation of Bcl2l1 26 0.41 21.66 3.81 100.00
129 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71 100.00
130 INT191678 Gene_expression of Xiap 60 0.71 57.25 1.37 100.00
131 INT122950 Binding of BAK1 16 0.41 12.85 0.31 100.00
132 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 100.00
133 INT123815 Gene_expression of Parp1 42 0.67 27.82 3.02 100.00
134 INT86534 Positive_regulation of MAPK14 81 0.62 57.81 23.62 100.00
135 INT99506 Negative_regulation of Bcl2l1 25 0.58 15.7 6.09 100.00
136 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62 100.00
137 INT71174 Gene_expression of CASP1 44 0.75 30.3 9.37 100.00
138 INT108203 Negative_regulation of Gene_expression of AKT1 28 0.54 16.38 3.19 100.00
139 INT123752 Regulation of Bax 19 0.60 16.45 4 100.00
140 INT88020 Positive_regulation of Fas 32 0.70 19.78 9.97 100.00
141 INT69436 Negative_regulation of Gene_expression of ROS1 81 0.38 46.58 12.22 100.00
142 INT224643 Positive_regulation of Gene_expression of Tnfsf10 13 0.46 11.1 1.67 100.00
143 INT147555 Negative_regulation of Birc2 12 0.57 14.1 0.43 100.00
144 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 100.00
145 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 100.00
146 INT9660 Regulation of TNF 363 0.62 312.94 139.99 100.00
147 INT198052 Positive_regulation of Gene_expression of MCL1 19 0.48 24.19 0.47 100.00
148 INT102752 Positive_regulation of Gene_expression of BCL2L1 14 0.67 13.8 2.19 100.00
149 INT140296 Negative_regulation of XIAP 9 0.45 13.61 1.37 100.00
150 INT74293 Positive_regulation of BAK1 13 0.60 14.13 2.73 100.00
151 INT151168 Gene_expression of Pten 60 0.78 35.63 10.54 100.00
152 INT112003 Localization of ROS1 94 0.73 66.32 12.16 100.00
153 INT89966 Negative_regulation of Fas 26 0.58 24.83 3.5 100.00
154 INT18522 Positive_regulation of Gene_expression of IFNA1 248 0.67 160.85 44.87 100.00
155 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3 100.00
156 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 100.00
157 INT88917 Positive_regulation of Casp8 18 0.60 14.64 1.36 100.00
158 INT230467 Gene_expression of MT1JP 23 0.62 24.26 0.83 100.00
159 INT80685 Gene_expression of MAPK8 90 0.72 51.91 13.36 100.00
160 INT64233 Regulation of Trp53 35 0.62 27.11 1.53 100.00
161 INT151983 Negative_regulation of CFLAR 13 0.57 13.51 2.05 100.00
162 INT81626 Positive_regulation of Positive_regulation of Casp3 34 0.69 16.75 12.18 100.00
163 INT182312 Positive_regulation of Gene_expression of Birc5 26 0.69 25.3 2.32 100.00
164 INT127698 Localization of AIFM1 15 0.79 13.45 4.74 100.00
165 INT201652 Positive_regulation of Tnfsf10 26 0.68 26.79 2.14 100.00
166 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 100.00
167 INT62800 Regulation of BAK1 7 0.41 10.12 1.47 100.00
168 INT66038 Positive_regulation of Ngfr 32 0.69 26.07 11.75 100.00
169 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 100.00
170 INT172808 Positive_regulation of Positive_regulation of ROS1 35 0.40 31.39 2.27 100.00
171 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 100.00
172 INT145929 Regulation of Bax 20 0.60 18.12 5.35 100.00
173 INT83794 Positive_regulation of Gene_expression of Bcl2l1 26 0.69 16.89 4.28 100.00
174 INT138915 Gene_expression of Stat1 144 0.77 69.53 5.85 100.00
175 INT116194 Gene_expression of Casp8 14 0.75 14.61 2.13 100.00
176 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 100.00
177 INT69435 Negative_regulation of ROS1 74 0.51 50.38 13.71 100.00
178 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45 100.00
179 INT104931 Binding of TNFSF10 15 0.36 17.44 2.07 100.00
180 INT98132 Regulation of FAS 16 0.42 20.57 2.06 100.00
181 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 100.00
182 INT93094 Gene_expression of Bak1 13 0.52 13.94 1.02 100.00
183 INT97749 Regulation of BCL2L1 10 0.41 9.72 1.65 100.00
184 INT147554 Gene_expression of Birc2 11 0.75 10.93 0.6 100.00
185 INT89676 Gene_expression of BID 8 0.31 8.98 0.1 100.00
186 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58 100.00
187 INT108589 Negative_regulation of Gene_expression of CASP3 13 0.57 10.52 2.14 100.00
188 INT182318 Regulation of Birc5 25 0.60 23.58 2.29 100.00
189 INT17892 Gene_expression of Myc 57 0.75 36.37 5.82 100.00
190 INT99507 Positive_regulation of Bcl2l1 17 0.69 9.23 4.97 100.00
191 INT99508 Regulation of Bcl2l1 12 0.61 10.44 2.71 100.00
192 INT97748 Positive_regulation of BCL2L1 12 0.67 9.83 2.26 100.00
193 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 100.00
194 INT141183 Gene_expression of Casp9 9 0.75 11.96 2.46 100.00
195 INT228128 Gene_expression of Bcl2l11 31 0.67 18.31 1.25 100.00
196 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 100.00
197 INT144697 Regulation of Gene_expression of Bax 8 0.37 9.5 0.81 100.00
198 INT86247 Gene_expression of Bcl2l10 14 0.34 12.21 1.61 100.00
199 INT175507 Regulation of Gene_expression of Bax 13 0.50 10.91 0.95 100.00
200 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89 100.00
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