D:Arcus Senilis

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pChart

Disease Term
Synonyms Arcus Corneal, Corneal Arcus
Documents 7
Hot Single Events 0
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Arcus Senilis. They are ordered first by their relevance to Arcus Senilis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT353795 Binding of Cd320 and Apob 1 0.08 0.82 0 5.00
2 INT344643 Egfl7 Regulation of CIMT 1 0.00 0.2 0 5.00
3 INT353798 Binding of Hdl1 and Apob 1 0.01 0.82 0 5.00
4 INT344644 CIMT Positive_regulation of Positive_regulation of Asap1 1 0.02 0.4 0 5.00
5 INT353799 Binding of Cd320 and Hdl1 1 0.03 0.83 0 5.00
6 INT353802 Binding of APOE and Apob 1 0.05 0.83 0 5.00
7 INT286444 PCSK9 Positive_regulation of Apob 1 0.02 0.49 0 5.00
8 INT353801 Binding of APOE and Cd320 1 0.22 0.83 0 5.00
9 INT353796 Binding of Ldlr and Apob 1 0.06 0.82 0 5.00
10 INT353804 Binding of APOE and Ldlr 1 0.16 0.84 0 5.00
11 INT353797 Binding of Ldlr and Trf 1 0.04 0.19 0 5.00
12 INT353800 Binding of Ldlr and Cd320 1 0.29 0.83 0 5.00
13 INT353803 Binding of APOE and Hdl1 1 0.01 0.83 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Arcus Senilis. They are ordered first by their pain relevance and then by number of times they were reported in Arcus Senilis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT142800 Positive_regulation of Ldlr 21 0.68 14.75 0.6 61.84
2 INT129425 Negative_regulation of Ldlr 22 0.42 17.15 0.97 48.80
3 INT44873 Negative_regulation of LCAT 16 0.59 6.92 3.13 42.96
4 INT39005 Negative_regulation of FBN1 7 0.42 4.97 2.6 42.96
5 INT353775 Negative_regulation of Ldlrap1 1 0.02 1 0 30.56
6 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 5.00
7 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 5.00
8 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41 5.00
9 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 5.00
10 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 5.00
11 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 5.00
12 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06 5.00
13 INT58288 Positive_regulation of Gene_expression of Crp 83 0.61 82.23 23.7 5.00
14 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31 5.00
15 INT20611 Gene_expression of Asap1 55 0.65 23.71 14.62 5.00
16 INT26545 Gene_expression of Hras1 173 0.78 79.54 13.21 5.00
17 INT105670 Gene_expression of AAVS1 131 0.75 49.24 12.95 5.00
18 INT32203 Negative_regulation of Crp 48 0.58 32.77 11.89 5.00
19 INT37390 Regulation of Crp 39 0.46 28.74 11.45 5.00
20 INT135022 Gene_expression of Cd14 79 0.76 36.37 10.63 5.00
21 INT135407 Negative_regulation of Ccl2 33 0.57 32.74 9.45 5.00
22 INT138700 Negative_regulation of Gene_expression of Ccl2 27 0.57 24.1 9.08 5.00
23 INT31582 Gene_expression of Hdl1 103 0.66 118.95 6.42 5.00
24 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21 5.00
25 INT20612 Positive_regulation of Asap1 36 0.68 24.35 6.06 5.00
26 INT39758 Gene_expression of Fn1 57 0.65 34.38 6.02 5.00
27 INT120550 Negative_regulation of Rock1 27 0.42 18.38 5.66 5.00
28 INT26546 Positive_regulation of Gene_expression of Hras1 35 0.70 16.59 4.54 5.00
29 INT17685 Negative_regulation of Cog1 23 0.42 15.65 3.56 5.00
30 INT181355 Regulation of Gene_expression of Ccl2 12 0.44 10.37 3.21 5.00
31 INT224413 Positive_regulation of CIMT 25 0.68 23.61 3.14 5.00
32 INT80550 Positive_regulation of Gene_expression of Asap1 8 0.42 5.8 3.09 5.00
33 INT9055 Positive_regulation of Cog1 22 0.68 14.08 2.95 5.00
34 INT172177 Protein_catabolism of INCENP 18 0.37 6.34 2.91 5.00
35 INT194465 Gene_expression of Ldlr 27 0.76 31.36 2.73 5.00
36 INT19177 Negative_regulation of GRHPR 19 0.53 12.65 2.71 5.00
37 INT50080 Binding of APOE 38 0.45 29.61 2.67 5.00
38 INT192541 Gene_expression of Tg(Foxn1)E1Hon 20 0.20 8.98 2.4 5.00
39 INT69789 Binding of Fn1 13 0.36 5.08 2.18 5.00
40 INT105669 Positive_regulation of Gene_expression of AAVS1 20 0.49 9.02 2.06 5.00
41 INT187994 Binding of CIMT 20 0.47 12.97 2.04 5.00
42 INT17890 Negative_regulation of HMGCR 26 0.42 12.05 1.94 5.00
43 INT135029 Positive_regulation of Gene_expression of Cd14 11 0.66 6.4 1.75 5.00
44 INT36529 Gene_expression of Mela 39 0.69 12.05 1.73 5.00
45 INT6830 Positive_regulation of Notch1 20 0.55 7.91 1.57 5.00
46 INT22836 Regulation of F2 9 0.59 2.3 1.49 5.00
47 INT224414 Regulation of CIMT 15 0.39 11.75 1.42 5.00
48 INT37799 Gene_expression of Apob 13 0.56 10.59 1.36 5.00
49 INT79357 Binding of ERVW-1 32 0.43 16.06 1.35 5.00
50 INT53261 Gene_expression of exf 5 0.07 4.93 1.24 5.00
51 INT224415 Gene_expression of CIMT 28 0.57 12.35 1.15 5.00
52 INT108559 Gene_expression of Pol 46 0.45 30.07 1.14 5.00
53 INT180095 Gene_expression of Rock1 22 0.55 4.9 1.14 5.00
54 INT136831 Gene_expression of Nodal 6 0.22 5.68 0.97 5.00
55 INT145119 Gene_expression of Cor 11 0.65 3.24 0.93 5.00
56 INT10827 Gene_expression of Apob 16 0.78 13.08 0.9 5.00
57 INT9467 Negative_regulation of APOB 14 0.57 10.49 0.88 5.00
58 INT10828 Regulation of Apob 7 0.39 7.55 0.83 5.00
59 INT189791 Negative_regulation of Gene_expression of Cd14 9 0.40 4.2 0.82 5.00
60 INT79941 Negative_regulation of Npc1 9 0.59 3.97 0.82 5.00
61 INT51739 Negative_regulation of Apob 9 0.42 4.21 0.78 5.00
62 INT129115 Negative_regulation of Cdkn2a 16 0.50 17.03 0.76 5.00
63 INT61423 Gene_expression of Egfl7 23 0.14 24.96 0.66 5.00
64 INT142802 Binding of Ldlr 8 0.47 5.08 0.65 5.00
65 INT133589 Negative_regulation of Pol 6 0.25 2.84 0.61 5.00
66 INT192841 Binding of Mela 9 0.43 4.29 0.58 5.00
67 INT227457 Positive_regulation of Gene_expression of CIMT 9 0.15 3.19 0.54 5.00
68 INT212966 Negative_regulation of Gene_expression of Hdl1 8 0.27 10.98 0.49 5.00
69 INT198884 Gene_expression of Vldlr 13 0.70 2.41 0.44 5.00
70 INT238793 Gene_expression of Cbl 6 0.03 3.01 0.43 5.00
71 INT252223 Positive_regulation of Gene_expression of Ldlr 3 0.55 10.28 0.37 5.00
72 INT205274 Gene_expression of Cs 2 0.75 2.08 0.36 5.00
73 INT46843 Binding of Trf 10 0.47 3.45 0.35 5.00
74 INT1626 Binding of Cog1 8 0.21 7.86 0.34 5.00
75 INT339386 Negative_regulation of Gene_expression of Apob 3 0.43 1.91 0.34 5.00
76 INT232235 Negative_regulation of Gene_expression of Ldlr 3 0.42 3.13 0.34 5.00
77 INT89584 Regulation of Gene_expression of Asap1 2 0.18 0.31 0.33 5.00
78 INT229279 Negative_regulation of Cby1 15 0.42 9.4 0.31 5.00
79 INT187410 Localization of Cd320 14 0.78 9.03 0.31 5.00
80 INT9054 Negative_regulation of Positive_regulation of Cog1 3 0.08 1.38 0.28 5.00
81 INT198492 Localization of Sumo1 3 0.24 0 0.21 5.00
82 INT333881 Gene_expression of GAG 2 0.75 0.4 0.2 5.00
83 INT252222 Regulation of Ldlr 5 0.34 4.3 0.19 5.00
84 INT315025 Gene_expression of Cacna1s 3 0.48 2.3 0.18 5.00
85 INT290336 Negative_regulation of Scarb1 4 0.31 1.77 0.17 5.00
86 INT241419 Binding of Rock1 4 0.25 1.93 0.16 5.00
87 INT187405 Gene_expression of Cand1 8 0.65 7.25 0.16 5.00
88 INT213081 Negative_regulation of Egfl7 7 0.04 5.14 0.15 5.00
89 INT203827 Localization of Apob 3 0.32 1.81 0.13 5.00
90 INT61420 Positive_regulation of Gene_expression of Egfl7 20 0.12 18.96 0.13 5.00
91 INT198900 Positive_regulation of Vldlr 3 0.26 1.44 0.12 5.00
92 INT239292 Positive_regulation of Gene_expression of Cor 3 0.49 1.41 0.12 5.00
93 INT261601 Binding of Emr1 2 0.02 1.34 0.08 5.00
94 INT239221 Negative_regulation of Cacna1s 4 0.04 2.24 0.07 5.00
95 INT293307 Regulation of Gene_expression of Ldlr 3 0.19 2.77 0.07 5.00
96 INT314131 Positive_regulation of Prdm16 2 0.67 1.56 0.06 5.00
97 INT344634 Negative_regulation of Binding of Fn1 1 0.41 0.49 0.05 5.00
98 INT344642 Regulation of Gene_expression of NOSIP 1 0.00 0.38 0.05 5.00
99 INT344641 Gene_expression of NOSIP 1 0.01 0.37 0.05 5.00
100 INT344635 Negative_regulation of Binding of Rock1 1 0.04 0.24 0.04 5.00
101 INT189923 Binding of Pol 5 0.20 2.09 0.04 5.00
102 INT240615 Binding of Apob 2 0.07 0.85 0.04 5.00
103 INT353774 Protein_catabolism of Lvs 1 0.12 0.92 0.04 5.00
104 INT344636 Negative_regulation of Npc1l1 1 0.01 0 0.03 5.00
105 INT344639 Positive_regulation of Gene_expression of Cacna1s 1 0.05 0.21 0.03 5.00
106 INT325018 Regulation of Gene_expression of Apob 2 0.16 1.59 0.03 5.00
107 INT353783 Positive_regulation of Gene_expression of Vldlr 1 0.28 0.51 0 5.00
108 INT353785 Negative_regulation of Gene_expression of Gag protein 1 0.57 0 0 5.00
109 INT353790 Negative_regulation of SNORD3@ 1 0.07 0.24 0 5.00
110 INT353789 Positive_regulation of SNORD3@ 1 0.12 0.05 0 5.00
111 INT290205 Negative_regulation of Protein_catabolism of AAVS1 2 0.20 0.7 0 5.00
112 INT176092 Negative_regulation of Gene_expression of Hras1 5 0.03 3.31 0 5.00
113 INT297928 Positive_regulation of Positive_regulation of CIMT 2 0.15 2.24 0 5.00
114 INT241211 Negative_regulation of CIMT 8 0.37 2.67 0 5.00
115 INT353778 Gene_expression of Pcsk9 1 0.42 0.36 0 5.00
116 INT286085 Binding of Cand1 3 0.36 1.25 0 5.00
117 INT353784 Protein_catabolism of Ldlr 1 0.52 1.85 0 5.00
118 INT290207 Protein_catabolism of AAVS1 2 0.35 0.69 0 5.00
119 INT344640 Regulation of Gene_expression of CIMT 1 0.14 0.24 0 5.00
120 INT353777 Positive_regulation of Setbp1 1 0.16 0.72 0 5.00
121 INT353792 Binding of SNORD3@ 1 0.06 0 0 5.00
122 INT285142 Negative_regulation of Mela 2 0.15 0.35 0 5.00
123 INT286443 Positive_regulation of PCSK9 1 0.16 0.48 0 5.00
124 INT353780 Binding of Smarcb1 1 0.01 0.22 0 5.00
125 INT344633 Negative_regulation of Cs 1 0.42 0.82 0 5.00
126 INT353787 Regulation of Gene_expression of Pcsk9 1 0.24 0.36 0 5.00
127 INT353779 Positive_regulation of Rnu5g 1 0.01 0 0 5.00
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