D:Arrhythmia Under Development

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Disease Term
Synonyms Arrhythmia, ARRHYTHMIA ATRIAL, Arrhythmia Neonatal, Arrhythmia Nodal, Arrhythmia Ventricular, Arrhythmic Disorder, Arrythmia Sinus, ATRIAL ARRHYTHMIA, Atrial Extrasystoles, Atrial Rhythm Disturbance, CARDIAC ARRHYTHMIA
Documents 3491
Hot Single Events 200
Hot Interactions 21

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Arrhythmia Under Development. They are ordered first by their relevance to Arrhythmia Under Development and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT247819 Cxadr Regulation of Gene_expression of Rasa1 1 0.06 1.04 0.04 99.06
2 INT297211 Negative_regulation of Myoz1 Negative_regulation of Gene_expression of Car2 1 0.03 0.6 0.05 98.52
3 INT214012 Binding of Ank1 and Nav1 1 0.01 0.51 0.1 97.20
4 INT214011 Negative_regulation of Binding of Ank1 and Nav1 1 0.01 0.51 0.1 97.20
5 INT214014 Binding of Dysf and Nav1 1 0.00 0.5 0.1 96.48
6 INT214016 Dysf Negative_regulation of Binding of Dysf and Nav1 1 0.00 0.5 0.1 96.48
7 INT353204 TNNT1 Regulation of Chkb 1 0.08 0.19 0.04 95.44
8 INT297210 Nfatc1 Regulation of Myoz1 1 0.06 0.51 0.07 95.12
9 INT353203 TNNT1 Regulation of Tnnt3 1 0.26 0.19 0.04 94.32
10 INT264988 Binding of CYP2C19 and CYP3A4 1 0.18 0.72 1.09 93.72
11 INT264987 Binding of CYP2C9 and CYP3A4 1 0.19 0.71 1.08 93.36
12 INT214015 Negative_regulation of Binding of Dnahc8 and Ank2 1 0.04 1.09 0.04 92.08
13 INT214013 Binding of Dnahc8 and Ank2 1 0.03 1.08 0.04 91.44
14 INT350859 Hist1h1t Regulation of Gene_expression of Kcnj5 1 0.02 0.37 0.59 87.48
15 INT247821 Binding of Tjp1 and Gopc 1 0.03 0.4 0 85.84
16 INT247823 Binding of Cxadr and Tjp1 1 0.08 0.4 0 85.84
17 INT350862 Hist1h1t Regulation of Kcnj5 1 0.02 1.35 1.22 83.96
18 INT28562 SOD1 Negative_regulation of Pacs1 1 0.03 2.63 0.19 83.20
19 INT350861 Hist1h1t Positive_regulation of Gene_expression of Kcnj5 1 0.02 0.35 0.56 83.08
20 INT153765 Positive_regulation of Edn1 Positive_regulation of Gtf3a 2 0.04 2.26 0.82 80.16
21 INT153766 Edn1 Positive_regulation of Gtf3a 1 0.04 1.25 0.41 80.16
22 INT297207 Myoz1 Regulation of Gene_expression of Slc8a1 1 0.09 0.26 0.03 76.92
23 INT279242 Negative_regulation of Binding of GLA and SH3GL3 1 0.08 1.22 0 74.40
24 INT279240 Binding of GLA and SH3GL3 1 0.07 1.21 0 73.52
25 INT350860 Hist1h1t Positive_regulation of Kcnj5 1 0.02 0.54 0.5 70.88
26 INT343027 Binding of CYP3A4 and Azi1 1 0.02 0.75 0.14 70.52
27 INT297214 Myoz1 Regulation of Gene_expression of Car2 1 0.03 0.5 0.06 70.36
28 INT182816 EEF1A2 Negative_regulation of CRP 1 0.28 1.84 0.21 67.84
29 INT311295 Gopc Positive_regulation of Gene_expression of Clcn1 1 0.07 0.29 0 66.64
30 INT309953 Binding of Atrn and Nav1 1 0.00 0.23 0.53 61.84
31 INT84607 Oprl1 Regulation of Adrb3 1 0.19 0.25 0.24 61.20
32 INT210898 IGHD1-14 Regulation of SELE 1 0.22 1.51 0 57.60
33 INT28705 F7 Negative_regulation of TFPI 1 0.02 0.66 0.06 55.12
34 INT224922 Binding of FAP and TARM1 1 0.06 1.4 0.06 54.20
35 INT239402 Binding of NPPA and ASAP1 1 0.19 1.24 0.04 54.16
36 INT247820 Gjc1 Regulation of Gja5 1 0.08 1.24 0 51.04
37 INT311298 Binding of DMPK and Mbnl1 1 0.43 0.54 0 45.28
38 INT178437 Mapk8 Positive_regulation of Jun 3 0.40 2.69 0.58 44.16
39 INT308495 Pcsk5 Regulation of CFI 1 0.01 0.22 0.85 37.56
40 INT310564 Positive_regulation of Ephb1 Regulation of Stat3 1 0.03 0.17 0.08 27.92
41 INT239401 FIG4 Regulation of NPPA 1 0.17 2.24 0 26.28
42 INT224921 Binding of TTR and TARM1 1 0.06 1.06 0 24.44
43 INT190824 Binding of Cl and Bcl2 1 0.02 1.4 0.05 8.00
44 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 5.00
45 INT83425 Binding of CD40LG and IGHG3 11 0.21 4.56 2.09 5.00
46 INT108409 AGT Positive_regulation of AGTR2 2 0.31 1.49 1.11 5.00
47 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
48 INT215584 P2rx1 Regulation of Localization of Gabrg1 1 0.01 0 0.92 5.00
49 INT182814 Binding of ICAM1 and PECAM1 2 0.02 3.32 0.77 5.00
50 INT170127 Binding of ITGAL and PECAM1 2 0.01 2.71 0.75 5.00
51 INT311470 Binding of Crp and Il1 1 0.00 2.44 0.63 5.00
52 INT311466 Binding of Acsl1 and Il1 1 0.00 2.46 0.63 5.00
53 INT326471 Binding of ATP6V0A1 and IGKV2D-29 1 0.00 0.09 0.62 5.00
54 INT330984 Negative_regulation of CYP2D6 Positive_regulation of Localization of CYP1A2 1 0.46 0 0.62 5.00
55 INT182819 Binding of CD63 and PECAM1 1 0.00 1.63 0.61 5.00
56 INT311467 Binding of Crp and Acsl1 1 0.00 2.31 0.61 5.00
57 INT182815 Binding of CD63 and ICAM1 1 0.00 1.63 0.61 5.00
58 INT352496 AVP Regulation of Gene_expression of CRS 1 0.27 2.47 0.59 5.00
59 INT315334 Binding of CYP3A4 and CDIPT 3 0.04 0.85 0.59 5.00
60 INT222691 Negative_regulation of Binding of FLNA and TNF 1 0.14 1.92 0.54 5.00
61 INT222692 Binding of FLNA and TNF 1 0.12 1.92 0.53 5.00
62 INT182813 EEF1A2 Negative_regulation of ITGAL 1 0.10 1.53 0.51 5.00
63 INT271344 MPO Regulation of Protein_catabolism of ACCS 1 0.02 2.42 0.51 5.00
64 INT277063 CRP Positive_regulation of Gene_expression of MMP10 1 0.39 1.53 0.48 5.00
65 INT217760 Il1f5 Positive_regulation of Gene_expression of Cpox 1 0.00 0.27 0.47 5.00
66 INT277065 CRP Positive_regulation of Gene_expression of MMP1 1 0.41 1.52 0.47 5.00
67 INT217759 Il1f5 Positive_regulation of Cpox 1 0.00 0.27 0.47 5.00
68 INT277064 CRP Positive_regulation of Gene_expression of TIMP1 1 0.15 1.47 0.45 5.00
69 INT215564 Hmmr Negative_regulation of P2ry2 1 0.00 0 0.44 5.00
70 INT326473 Positive_regulation of PGAP1 Positive_regulation of ROS1 1 0.00 0.07 0.41 5.00
71 INT326470 PGAP1 Positive_regulation of ROS1 1 0.00 0.07 0.4 5.00
72 INT275156 Agt Positive_regulation of Rac1 1 0.03 2.89 0.4 5.00
73 INT171990 Binding of DMD and VDR 5 0.05 2.58 0.39 5.00
74 INT326472 AGXT Negative_regulation of PGAP1 1 0.00 0.05 0.39 5.00
75 INT353391 Binding of DRD4 and GRB2 1 0.37 0.62 0.37 5.00
76 INT353392 Binding of DRD4 and NCK1 1 0.37 0.62 0.37 5.00
77 INT353390 Binding of DRD4 and SRC 1 0.25 0.62 0.37 5.00
78 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31 5.00
79 INT222690 TNF Positive_regulation of Gene_expression of NPEPPS 1 0.01 1.03 0.3 5.00
80 INT187361 Binding of Gabrg1 and Kcnn3 1 0.36 0.13 0.3 5.00
81 INT271350 MPO Positive_regulation of TIMP1 1 0.05 1.66 0.29 5.00
82 INT299956 Binding of PPARA and EPC1 1 0.09 0.34 0.29 5.00
83 INT182817 EEF1A2 Positive_regulation of BMP2 1 0.26 1.62 0.28 5.00
84 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28 5.00
85 INT170258 Pecam1 Positive_regulation of Icam1 1 0.02 0.79 0.27 5.00
86 INT329369 Jun Regulation of Gene_expression of Il12a 1 0.00 1.48 0.27 5.00
87 INT235013 Binding of DSG1 and Adam17 1 0.07 1.34 0.26 5.00
88 INT234980 Positive_regulation of Egfr Positive_regulation of Adam17 1 0.09 1.33 0.26 5.00
89 INT277066 MMP1 Positive_regulation of Gene_expression of TIMP1 1 0.16 0.76 0.24 5.00
90 INT231206 Binding of KCNH2 and KCNQ1 2 0.22 1.04 0.24 5.00
91 INT329368 Ccl2 Negative_regulation of Jun 1 0.01 1.87 0.24 5.00
92 INT89612 Binding of FABP3 and MB 3 0.34 1.49 0.22 5.00
93 INT311872 IGHE Positive_regulation of Localization of Mmp9 1 0.01 1.35 0.22 5.00
94 INT277072 Binding of PLA2G7 and Lipg 1 0.00 1.32 0.21 5.00
95 INT194100 Binding of MKLN1 and HELT 1 0.01 1.23 0.21 5.00
96 INT234992 Car2 Positive_regulation of Jup 1 0.02 0.27 0.2 5.00
97 INT318039 CDIPT Positive_regulation of CYP3A4 1 0.06 0.06 0.2 5.00
98 INT275159 Agt Positive_regulation of Phosphorylation of Stat3 1 0.04 1.44 0.2 5.00
99 INT235014 Car2 Positive_regulation of DSP 1 0.06 0.28 0.2 5.00
100 INT210551 Binding of KCNH2 and KCNE2 1 0.08 0 0.19 5.00
101 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19 5.00
102 INT217665 ADIPOQ Positive_regulation of INS 2 0.06 1.8 0.19 5.00
103 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19 5.00
104 INT348059 Dbi Negative_regulation of Binding of Mpo 1 0.08 0.43 0.19 5.00
105 INT330986 CYP2C9 Positive_regulation of Gene_expression of CYP3A4 1 0.39 0 0.18 5.00
106 INT330985 CYP2C9 Positive_regulation of Gene_expression of CYP2C19 1 0.34 0 0.18 5.00
107 INT196303 Binding of SCN5A and ACCS 1 0.00 1.43 0.18 5.00
108 INT347446 CD99 Positive_regulation of Binding of DES 1 0.46 1.01 0.17 5.00
109 INT350363 Gatm Negative_regulation of NOS1 1 0.00 0.31 0.17 5.00
110 INT347445 CD99 Positive_regulation of BCL2 1 0.17 0.95 0.16 5.00
111 INT240768 Binding of F2 and F13A1 1 0.07 2.25 0.15 5.00
112 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15 5.00
113 INT292749 Akt1 Positive_regulation of Ctnnd2 1 0.09 1.73 0.15 5.00
114 INT292748 Akt1 Negative_regulation of Positive_regulation of Casp3 1 0.01 1.81 0.15 5.00
115 INT217667 LEP Negative_regulation of Localization of INS 1 0.15 1.18 0.14 5.00
116 INT257937 Binding of CSF2 and INVS 1 0.04 1.1 0.14 5.00
117 INT315030 Binding of Cav1 and Tmie 1 0.03 0.25 0.14 5.00
118 INT291967 INA Positive_regulation of NA 1 0.00 0.98 0.14 5.00
119 INT217664 LEP Negative_regulation of INS 1 0.15 1.18 0.14 5.00
120 INT315032 Binding of Cav1 and Ryr1 1 0.27 0.2 0.14 5.00
121 INT284570 Binding of Avp and Il6 1 0.04 2.17 0.13 5.00
122 INT271345 Negative_regulation of PIGF Negative_regulation of FLT1 1 0.02 1.17 0.13 5.00
123 INT310412 Binding of CP and TF 1 0.14 1.66 0.13 5.00
124 INT329371 IL8 Negative_regulation of Jun 1 0.00 0.95 0.13 5.00
125 INT309954 Binding of Pkp2 and Nav1 1 0.29 0.29 0.13 5.00
126 INT258016 AGTR1 Positive_regulation of EGFR 1 0.15 1.24 0.13 5.00
127 INT307627 Binding of BMP1 and CSF2 1 0.01 0.33 0.12 5.00
128 INT311399 Binding of Celf1 and Uts2r 1 0.08 0.26 0.12 5.00
129 INT254643 Binding of Mapk8ip1 and Slc9a3r2 1 0.00 0.27 0.12 5.00
130 INT213144 TIMP1 Negative_regulation of THBD 1 0.04 1.16 0.12 5.00
131 INT224040 Mtpn Positive_regulation of P2RY1 1 0.00 0.85 0.12 5.00
132 INT181740 Il1 Positive_regulation of Csf2 1 0.02 0 0.12 5.00
133 INT213147 DAK Negative_regulation of THBD 1 0.00 1.16 0.12 5.00
134 INT311871 Cav1 Regulation of Mch 1 0.01 0.24 0.11 5.00
135 INT351427 Binding of PIK3C3 and RYR1 1 0.00 0 0.11 5.00
136 INT352497 AGT Positive_regulation of Binding of CRS 1 0.14 0.87 0.11 5.00
137 INT210899 Binding of SELE and IGHD1-14 1 0.39 3.31 0.11 5.00
138 INT231223 Binding of KCNQ1 and Nav1 1 0.03 0.59 0.11 5.00
139 INT275171 Binding of Stat3 and Rac1 Positive_regulation of Rac1 Positive_regulation of Stat3 1 0.01 0.73 0.1 5.00
140 INT258014 Binding of ANGPT2 and RASGRP1 1 0.00 1.58 0.1 5.00
141 INT284552 Binding of Cd8a and Mthfd1 2 0.03 1.32 0.1 5.00
142 INT334893 ACE Negative_regulation of Gene_expression of AGT 1 0.03 1.41 0.1 5.00
143 INT277692 Binding of Atp9a and Tnfrsf10b 1 0.00 1.47 0.1 5.00
144 INT275157 Binding of Stat3 and Rac1 1 0.05 0.71 0.1 5.00
145 INT224026 P2RY6 Positive_regulation of NRP2 1 0.10 0.98 0.1 5.00
146 INT271343 Binding of CRP and PAPPA 1 0.20 0.86 0.1 5.00
147 INT275158 Rac1 Positive_regulation of Stat3 1 0.07 0.72 0.1 5.00
148 INT258018 Binding of AGT and RASGRP1 1 0.00 1.59 0.1 5.00
149 INT224021 PIK3CG Negative_regulation of EPHB2 1 0.03 0.5 0.09 5.00
150 INT299955 Binding of KDR and FTSJ3 1 0.04 1.07 0.09 5.00
151 INT308225 Alb Positive_regulation of Binding of EIF4G2 1 0.02 0.33 0.09 5.00
152 INT299953 Binding of CD34 and FTSJ3 1 0.04 1.07 0.09 5.00
153 INT223088 Binding of ELF3 and NAGLU 1 0.14 0.84 0.09 5.00
154 INT271349 ACCS Positive_regulation of PAPPA 1 0.06 0.87 0.09 5.00
155 INT224020 MAPK1 Negative_regulation of EPHB2 1 0.08 0.56 0.09 5.00
156 INT223089 Binding of IDS and NAGLU 1 0.26 0.72 0.09 5.00
157 INT190825 Cl Regulation of Gopc 1 0.00 0.52 0.09 5.00
158 INT213145 DAK Positive_regulation of TIMP1 1 0.02 0.36 0.09 5.00
159 INT241040 Slc8a1 Negative_regulation of Gene_expression of Ca2 1 0.15 1.35 0.09 5.00
160 INT271347 Negative_regulation of Binding of TNNT2 and ACCS 1 0.01 0.67 0.08 5.00
161 INT271354 MPO Regulation of Gene_expression of CRP 1 0.16 1.74 0.08 5.00
162 INT271346 Binding of TNNT2 and ACCS 1 0.01 0.67 0.08 5.00
163 INT271351 MPO Positive_regulation of CRP 1 0.07 1.69 0.08 5.00
164 INT273520 NBN Positive_regulation of CDIPT 1 0.06 0.82 0.08 5.00
165 INT171709 Rac1 Negative_regulation of Localization of Chrna7 1 0.04 0.75 0.08 5.00
166 INT210897 Binding of SNRNP70 and IGHD1-14 1 0.01 1.63 0.08 5.00
167 INT320659 Vsig2 Positive_regulation of Transcription of Nos2 1 0.07 0.65 0.07 5.00
168 INT351651 Enpep Positive_regulation of Agt 1 0.22 0.93 0.07 5.00
169 INT291837 Binding of Pecam1 and Vegfa 1 0.09 1.1 0.07 5.00
170 INT351655 Avp Positive_regulation of Agt 1 0.11 0.94 0.07 5.00
171 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07 5.00
172 INT356379 DMD Positive_regulation of Negative_regulation of Utrn 1 0.54 0.84 0.07 5.00
173 INT230883 Binding of IGHE and tryptase 1 0.01 0.23 0.07 5.00
174 INT192309 Binding of GSTM1 and GSTT1 2 0.43 4.54 0.06 5.00
175 INT215565 Slc35a3 Positive_regulation of P2ry14 1 0.01 0.18 0.06 5.00
176 INT234968 IgG Negative_regulation of Jup 1 0.02 1.09 0.06 5.00
177 INT271355 PGF Positive_regulation of PIGF 1 0.01 0.99 0.06 5.00
178 INT311296 Akt1 Positive_regulation of Gene_expression of Clcn1 1 0.11 0 0.05 5.00
179 INT235006 IgG Positive_regulation of SRC 1 0.01 0.82 0.05 5.00
180 INT235010 Positive_regulation of Positive_regulation of SRC 1 0.01 0.84 0.05 5.00
181 INT258015 Binding of ANGPT2 and REN 1 0.01 0.59 0.05 5.00
182 INT217666 ADIPOQ Regulation of Gene_expression of INS 1 0.03 1.99 0.05 5.00
183 INT106823 Binding of MBP and PAPPA 2 0.17 3.89 0.05 5.00
184 INT299954 Negative_regulation of LXN Negative_regulation of FTSJ3 1 0.00 0.75 0.05 5.00
185 INT230868 Binding of MCS and TNF 1 0.04 0.77 0.05 5.00
186 INT244328 ELF3 Negative_regulation of Positive_regulation of SH3GL3 3 0.20 1.26 0.04 5.00
187 INT258012 ANGPT2 Positive_regulation of Binding of AGTR1 and ANGPT2 1 0.00 0.29 0.04 5.00
188 INT234990 Binding of Cish and Dsp 1 0.01 0.24 0.04 5.00
189 INT235003 Binding of NKS1 and Rdh2 1 0.00 0.18 0.04 5.00
190 INT234986 Binding of Rdh2 and Dsp 1 0.00 0.24 0.04 5.00
191 INT296893 Nps Negative_regulation of Gene_expression of REN 1 0.00 1.05 0.04 5.00
192 INT258020 Binding of AGTR1 and ANGPT2 1 0.03 0.29 0.04 5.00
193 INT351652 Enpep Positive_regulation of Positive_regulation of Agt 1 0.19 0.05 0.04 5.00
194 INT234994 Binding of NKS1 and Dsg3 1 0.00 0.5 0.04 5.00
195 INT235012 Binding of NKS1 and Dsp 1 0.00 0.24 0.04 5.00
196 INT199406 Binding of CYP3A4 and PPIB 1 0.40 0 0.04 5.00
197 INT234998 Binding of NKS1 and Cish 1 0.00 0.18 0.04 5.00
198 INT234991 Binding of Dsg3 and Positive_regulation of Pik3r1 1 0.05 0.32 0.03 5.00
199 INT230882 Binding of MCS and tryptase 1 0.03 0.23 0.03 5.00
200 INT351663 Binding of AGT and Agt 1 0.32 0.57 0.03 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Arrhythmia Under Development. They are ordered first by their pain relevance and then by number of times they were reported in Arrhythmia Under Development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT45427 Positive_regulation of Cacna2d2 20 0.49 11.89 4.85 100.00
2 INT15122 Negative_regulation of Cacna2d2 7 0.24 5.2 0.84 100.00
3 INT14238 Positive_regulation of Cd69 19 0.60 17.75 6.07 100.00
4 INT81766 Binding of Cacna2d2 7 0.23 2.57 1.25 100.00
5 INT193587 Negative_regulation of Pacs1 1 0.08 2.74 0 100.00
6 INT47161 Protein_catabolism of Cd69 1 0.45 1.71 0.6 100.00
7 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33 100.00
8 INT48286 Positive_regulation of Myl3 6 0.33 3.2 0.77 100.00
9 INT37111 Regulation of Negative_regulation of Mme 7 0.44 2.61 3.13 99.98
10 INT65642 Binding of Dync1h1 27 0.41 15.83 2.68 99.92
11 INT664 Positive_regulation of Fgg 14 0.46 8.75 2.11 99.92
12 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76 99.90
13 INT247792 Regulation of Bop1 1 0.00 0.6 0 99.80
14 INT149755 Transcription of P2rx3 13 0.60 8.28 2.11 99.76
15 INT49520 Gene_expression of P2rx3 121 0.78 61.15 49.24 99.76
16 INT5061 Negative_regulation of Mme 306 0.59 51.97 136.9 99.76
17 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 99.74
18 INT11709 Positive_regulation of Gene_expression of PIK3C2A 2 0.49 1.88 0.74 99.74
19 INT30023 Regulation of PAF1 7 0.17 1.84 1.38 99.72
20 INT112203 Negative_regulation of ACADM 1 0.51 4.02 0.22 99.60
21 INT266758 Localization of PEG10 1 0.65 0.29 0 99.60
22 INT120227 Binding of Cxadr 17 0.45 8.02 1.51 99.52
23 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48 99.52
24 INT188883 Binding of DDX41 9 0.39 11.55 1.29 99.46
25 INT95 Positive_regulation of Adrb1 34 0.62 11.95 14.41 99.44
26 INT4435 Gene_expression of PIK3C2A 20 0.77 14.43 2.48 99.42
27 INT39000 Regulation of pr 24 0.44 12.51 4.36 99.40
28 INT46460 Gene_expression of NAV1 288 0.78 135.51 305.75 99.32
29 INT167018 Negative_regulation of POR 3 0.37 1.9 0.11 99.28
30 INT96 Binding of Adrb1 18 0.48 2.8 8.52 99.28
31 INT10610 Negative_regulation of Plg 22 0.40 11.81 6.74 99.22
32 INT97 Negative_regulation of Adrb1 102 0.59 32.44 26.9 99.20
33 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 99.20
34 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45 99.20
35 INT84924 Positive_regulation of Gene_expression of NGF 29 0.68 17.91 16.46 99.20
36 INT4596 Positive_regulation of SCD 18 0.42 22.59 3.26 99.14
37 INT4577 Negative_regulation of Thra 24 0.56 3.75 4.73 99.12
38 INT67855 Negative_regulation of PPIG 64 0.57 17.83 13.54 99.08
39 INT2442 Localization of Mb 38 0.80 24.74 6.33 99.04
40 INT127144 Regulation of CD82 5 0.35 0.6 0.09 99.00
41 INT174158 Negative_regulation of Cxadr 23 0.55 13.74 0.72 98.98
42 INT233911 Negative_regulation of Nfatc1 2 0.54 2.66 0.38 98.96
43 INT297176 Regulation of Negative_regulation of Nfatc1 1 0.42 0.54 0.08 98.96
44 INT297198 Positive_regulation of Negative_regulation of Nfatc1 1 0.43 0.54 0.08 98.96
45 INT3854 Binding of SCD 16 0.41 11.14 3.7 98.92
46 INT97073 Positive_regulation of Ebp 6 0.42 2.68 1.8 98.92
47 INT3550 Negative_regulation of GLA 52 0.59 33.93 5.26 98.92
48 INT247803 Positive_regulation of Cdh2 2 0.11 2.03 0.04 98.90
49 INT91703 Negative_regulation of Myoz1 78 0.58 53.78 13.5 98.88
50 INT9556 Negative_regulation of NAV1 47 0.59 28.49 49.33 98.80
51 INT68758 Positive_regulation of Ros1 125 0.46 82.72 25.27 98.72
52 INT46714 Positive_regulation of TNNC1 76 0.67 75.99 6.66 98.68
53 INT9550 Gene_expression of TNNI3 113 0.78 86.79 10.56 98.66
54 INT351955 Gene_expression of Tro 1 0.44 1.38 0.33 98.48
55 INT6097 Negative_regulation of NEUROD1 30 0.57 9.71 6.24 98.44
56 INT1116 Regulation of Ren 103 0.62 27.66 33.26 98.44
57 INT2536 Gene_expression of E2R 1 0.01 0.54 0.11 98.44
58 INT92330 Gene_expression of WDTC1 22 0.47 13.12 5.15 98.40
59 INT24412 Localization of WDTC1 18 0.68 12.45 4.5 98.40
60 INT32007 Gene_expression of ECT 56 0.62 18.94 11.13 98.40
61 INT163359 Gene_expression of RFC1 9 0.65 3.34 2.64 98.36
62 INT40476 Negative_regulation of RFC1 5 0.18 2.85 0.72 98.36
63 INT182074 Negative_regulation of Gene_expression of RFC1 1 0.03 0.76 0.08 98.36
64 INT7093 Negative_regulation of CYP2B6 146 0.58 37.3 48.39 98.34
65 INT160134 Regulation of Hcn1 2 0.38 0.54 0.7 98.32
66 INT214005 Gene_expression of Ank2 1 0.78 29.4 1.88 98.28
67 INT188993 Gene_expression of MKLN1 2 0.38 9.71 1.43 98.28
68 INT90943 Negative_regulation of P2rx1 13 0.42 8.21 7.22 98.24
69 INT93207 Negative_regulation of Cyp4a3 11 0.36 4.32 2.63 98.22
70 INT110930 Binding of Ces2a 1 0.37 0.27 0.43 98.12
71 INT170516 Negative_regulation of Gene_expression of Car2 35 0.35 9.4 5.48 98.08
72 INT60279 Gene_expression of VHL 70 0.78 75.21 2.21 98.06
73 INT191783 Positive_regulation of Pnp 21 0.67 22.51 1.66 98.04
74 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 98.02
75 INT1430 Regulation of PDYN 88 0.60 16.99 60.32 97.80
76 INT83952 Gene_expression of Cxadr 24 0.75 22.38 6.77 97.72
77 INT226835 Gene_expression of Cdh2 14 0.22 8.04 0.31 97.60
78 INT55294 Gene_expression of Slc2a4 17 0.70 6.84 1.11 97.58
79 INT11673 Positive_regulation of ECT 43 0.59 13.93 11.25 97.48
80 INT2512 Negative_regulation of Cp 27 0.51 10.15 8.37 97.48
81 INT12010 Gene_expression of Cp 38 0.65 20.55 7.84 97.48
82 INT63238 Gene_expression of Mt1 27 0.65 10.86 2.53 97.40
83 INT74871 Negative_regulation of Gene_expression of Mt1 3 0.26 1.8 0.48 97.40
84 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 97.40
85 INT230668 Gene_expression of Rasa1 9 0.68 3.25 1.74 97.38
86 INT84572 Gene_expression of Zmat3 67 0.07 37.61 5.86 97.28
87 INT161550 Negative_regulation of BLVRA 1 0.35 0.45 0.46 97.24
88 INT217757 Regulation of Kcne1 1 0.28 0.84 0.37 97.16
89 INT738 Regulation of POMC 459 0.62 111.19 243.74 97.16
90 INT108714 Positive_regulation of Zfp79-rs1 1 0.01 0.98 0.14 97.12
91 INT297175 Regulation of Localization of Myoz1 1 0.09 0.52 0.08 97.08
92 INT20023 Negative_regulation of Bckdha 1 0.00 1 0.15 97.08
93 INT161549 Negative_regulation of TDRD6 2 0.17 1.08 0.58 97.04
94 INT214009 Positive_regulation of Gene_expression of Ank2 1 0.70 2.86 0 97.00
95 INT2960 Regulation of Dbh 32 0.47 10.32 18.94 97.00
96 INT4616 Regulation of Maoa 40 0.62 6.09 15.94 97.00
97 INT172209 Regulation of HAL 3 0.25 2.23 0.13 97.00
98 INT1536 Negative_regulation of NA 244 0.55 52.67 59.79 96.92
99 INT34425 Positive_regulation of Negative_regulation of NA 12 0.38 4.17 3.2 96.92
100 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 96.80
101 INT119818 Negative_regulation of CHGA 10 0.57 8.21 2.04 96.80
102 INT1414 Regulation of Oprl1 169 0.62 32.05 139.99 96.76
103 INT171070 Positive_regulation of Hey2 8 0.05 10.12 1.96 96.76
104 INT51584 Regulation of KCNQ1 10 0.44 3.21 1.84 96.72
105 INT100743 Regulation of KCNH2 6 0.54 2.37 2.61 96.72
106 INT107407 Regulation of KCNE1 3 0.39 2.18 0.88 96.72
107 INT107406 Regulation of KCNC1 2 0.43 0.34 0.61 96.72
108 INT326 Gene_expression of Gnrhr 105 0.76 35.87 34.93 96.72
109 INT107405 Regulation of ASPH 1 0.08 0.19 0.23 96.72
110 INT247809 Negative_regulation of Binding of Cxadr 1 0.41 2.02 0 96.68
111 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 96.54
112 INT151115 Regulation of Regulation of Bcl2 4 0.21 4.12 0.88 96.54
113 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41 96.54
114 INT24266 Negative_regulation of IKZF1 6 0.37 1.55 0.96 96.48
115 INT131788 Positive_regulation of NPPB 87 0.67 86.1 8.81 96.48
116 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35 96.48
117 INT140388 Localization of Pvr 4 0.61 3.07 0.59 96.44
118 INT28176 Localization of Cp 17 0.73 14.3 4.86 96.20
119 INT211584 Gene_expression of Dmpk 32 0.73 12.28 0.46 96.12
120 INT255100 Positive_regulation of Gene_expression of Dmpk 8 0.56 3.3 0.13 96.12
121 INT58060 Negative_regulation of HMI 30 0.44 11.9 5.06 96.08
122 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04 96.00
123 INT1278 Negative_regulation of Ldha 93 0.59 37.66 19.36 95.84
124 INT190611 Gene_expression of Cnn1 13 0.56 5.87 0.75 95.76
125 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 95.72
126 INT539 Negative_regulation of Chrna7 14 0.42 4.59 6.42 95.72
127 INT93129 Negative_regulation of KCNH2 42 0.54 9.63 10.85 95.68
128 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 95.64
129 INT62127 Localization of SRI 12 0.45 10.21 1.54 95.40
130 INT21840 Positive_regulation of IL3 20 0.70 14.44 2.86 95.32
131 INT60552 Localization of TNNI3 56 0.79 20.05 1.44 95.28
132 INT3074 Negative_regulation of Chkb 29 0.57 14 12.04 95.20
133 INT190679 Localization of Myoz1 2 0.16 0.57 0.11 95.12
134 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 95.12
135 INT230722 Regulation of Hcm 4 0.37 3 0.21 95.04
136 INT1179 Negative_regulation of Ace 157 0.59 67.03 30.46 95.00
137 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88 94.96
138 INT129303 Positive_regulation of NAV1 54 0.70 36.92 57.45 94.96
139 INT96117 Negative_regulation of Tnnt2 3 0.13 1.61 1.1 94.88
140 INT172328 Negative_regulation of Phl1 1 0.03 61.51 0.97 94.80
141 INT258759 Regulation of Localization of ADHD1 3 0.38 4.71 0.32 94.76
142 INT214008 Negative_regulation of Ank1 4 0.03 1.49 0.09 94.68
143 INT49 Negative_regulation of Ren 129 0.59 37.48 35.62 94.64
144 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86 94.60
145 INT179693 Positive_regulation of DAK 14 0.04 6.02 1.4 94.60
146 INT1758 Positive_regulation of Gene_expression of TIMP1 62 0.69 31.72 13.98 94.60
147 INT234867 Localization of Jup 1 0.24 2.84 0.03 94.56
148 INT228409 Localization of DSP 5 0.73 2.39 0.11 94.56
149 INT234856 Localization of Dsc2 1 0.21 1.28 0 94.56
150 INT234914 Localization of Pkp2 1 0.06 1.47 0 94.56
151 INT234937 Localization of DSG1 5 0.66 4.14 0 94.56
152 INT4403 Binding of CYP2B6 113 0.48 21.17 33.83 94.48
153 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 94.24
154 INT50403 Negative_regulation of CYP2C19 55 0.59 8.97 17.79 94.24
155 INT59929 Negative_regulation of CYP2C9 60 0.59 16.33 15.39 94.24
156 INT44073 Negative_regulation of Binding of HRH2 2 0.43 0.86 0.66 94.12
157 INT183882 Positive_regulation of Gene_expression of PAF1 4 0.49 2.77 0.11 94.08
158 INT224924 Binding of TARM1 4 0.18 3.42 0.39 94.08
159 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 94.04
160 INT207165 Gene_expression of DAK 18 0.08 9.41 2.69 94.04
161 INT1212 Binding of Oprl1 312 0.48 28.6 225.15 94.00
162 INT153975 Localization of Fbln5 1 0.38 0.16 0.14 93.96
163 INT153976 Positive_regulation of Localization of Fbln5 1 0.26 0.16 0.14 93.96
164 INT213995 Positive_regulation of Ank2 1 0.50 2.86 0 93.88
165 INT297191 Binding of Ppp3r1 1 0.33 0.4 0 93.76
166 INT297192 Negative_regulation of Binding of Ppp3r1 1 0.38 0.4 0 93.76
167 INT194106 Positive_regulation of MKLN1 1 0.25 4.34 0.64 93.72
168 INT183877 Gene_expression of PAF1 13 0.75 5.33 0.48 93.72
169 INT273525 Regulation of NBN 1 0.49 1.28 0.05 93.60
170 INT93135 Binding of KCNC1 3 0.34 0.09 0.6 93.52
171 INT20260 Positive_regulation of Chkb 41 0.64 21.48 18.53 93.48
172 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43 93.48
173 INT185246 Gene_expression of Psmd1 26 0.50 8.89 3.73 93.44
174 INT70776 Positive_regulation of P2rx1 62 0.62 32.55 30.75 93.28
175 INT149435 Regulation of Positive_regulation of P2rx1 2 0.30 1.55 1.67 93.28
176 INT215550 Positive_regulation of Cigs1 1 0.04 0.91 0.47 93.28
177 INT215549 Regulation of Positive_regulation of Cigs1 1 0.04 0.92 0.47 93.28
178 INT3920 Localization of Ldha 241 0.81 83.08 58.72 93.20
179 INT31096 Binding of HRH2 7 0.37 2 2 93.20
180 INT73611 Negative_regulation of SCD 15 0.37 26.67 3.71 93.12
181 INT9973 Binding of MMVP1 14 0.48 22.66 1.79 93.12
182 INT1335 Negative_regulation of Oprl1 123 0.59 18.02 77.13 93.12
183 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 93.04
184 INT1416 Transcription of POMC 40 0.72 10.71 15.38 93.04
185 INT54039 Positive_regulation of Transcription of POMC 2 0.67 3.24 0.23 93.04
186 INT9552 Positive_regulation of TNNI3 209 0.70 128.67 19.15 92.88
187 INT636 Binding of MRAP 54 0.48 40.36 18.77 92.80
188 INT26273 Negative_regulation of RYR1 18 0.43 7.64 3.11 92.80
189 INT6508 Gene_expression of RYR1 34 0.77 11.11 2.04 92.80
190 INT158175 Positive_regulation of Gene_expression of RYR1 2 0.48 1.35 0.13 92.80
191 INT297181 Negative_regulation of Ppp3r1 1 0.52 2.3 0.07 92.56
192 INT297184 Localization of Ppp3r1 1 0.67 1.42 0 92.56
193 INT214007 Negative_regulation of Ank2 1 0.43 2.63 0.14 92.40
194 INT11710 Positive_regulation of SERPINC1 6 0.59 6.15 1.47 92.40
195 INT39587 Gene_expression of CP 42 0.65 31.48 11.87 92.40
196 INT236517 Gene_expression of Cacna1f 8 0.65 5.18 0.77 92.36
197 INT168933 Positive_regulation of Car5b 2 0.15 0.64 0.05 92.32
198 INT138216 Negative_regulation of PER1 13 0.37 9.66 4.55 92.32
199 INT170 Negative_regulation of Adrb1 52 0.55 13.46 14.78 92.32
200 INT246524 Binding of QPCT 4 0.05 3.65 0.72 92.32
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