D:Arsenic Poisoning

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Disease Term
Synonyms Arsenic Encephalopathies, Arsenic Encephalopathy, Arsenic Induced Polyneuropathies, Arsenic Induced Polyneuropathy, Arsenic Poisoning Inorganic, Arsenic Poisoning Nervous System, Arsenic Poisoning Organic, ARSENIC POISONINGS, ARSENIC POISONINGS INORGANIC, Arsenic Poisonings Organic, ARSENICAL NEUROTOXICITY SYNDROME
Documents 28
Hot Single Events 1
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Arsenic Poisoning. They are ordered first by their relevance to Arsenic Poisoning and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT330046 Mapk8 Negative_regulation of Prkcg 1 0.13 0.4 0.66 5.00
2 INT216127 EGR1 Regulation of Transcription of TP53 1 0.06 0.21 0.28 5.00
3 INT216128 EGR1 Regulation of TP53 1 0.11 0.21 0.27 5.00
4 INT330053 Binding of Ros1 and Mapk8 1 0.02 0.88 0.24 5.00
5 INT330051 Mapk8 Positive_regulation of Bcl2l11 1 0.13 0.46 0.21 5.00
6 INT216130 SRF Positive_regulation of Gene_expression of EGR1 1 0.49 0.32 0.07 5.00
7 INT216129 SRF Positive_regulation of Gene_expression of FOS 1 0.28 0.32 0.07 5.00
8 INT323392 SERPINH1 Negative_regulation of BCHE 1 0.02 0.52 0.04 5.00
9 INT323395 Binding of BCHE and SERPINH1 1 0.02 0.74 0.03 5.00
10 INT330047 Binding of Bax and Bcl2l11 1 0.13 0.62 0 5.00
11 INT330055 Binding of Bcl2l11 and Hrk 1 0.02 0.62 0 5.00
12 INT330048 G6pd Positive_regulation of Gene_expression of Ros1 1 0.03 0.61 0 5.00
13 INT323393 Positive_regulation of Binding of SERPINH1 and VRK1 1 0.01 0 0 5.00
14 INT323394 Binding of SERPINH1 and VRK1 1 0.00 0 0 5.00
15 INT330052 Binding of Bax and Bid 1 0.15 0.62 0 5.00
16 INT330057 Bid Positive_regulation of Bax 1 0.19 0.62 0 5.00
17 INT330056 Bcl2 Regulation of Localization of Cyct 1 0.27 0.97 0 5.00
18 INT330049 Prkcg Negative_regulation of Pnck 1 0.01 0.28 0 5.00
19 INT330054 Bcl2l11 Positive_regulation of Bax 1 0.25 0.62 0 5.00
20 INT330060 GSR Positive_regulation of Gene_expression of Ros1 1 0.00 0.61 0 5.00
21 INT330050 Binding of Bid and Hrk 1 0.02 0.62 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Arsenic Poisoning. They are ordered first by their pain relevance and then by number of times they were reported in Arsenic Poisoning. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT94827 Gene_expression of HBS1L 24 0.67 26.11 1.61 99.92
2 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 50.00
3 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 50.00
4 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 50.00
5 INT11650 Negative_regulation of Gpt 122 0.59 69.15 30.36 50.00
6 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 50.00
7 INT17565 Regulation of Gpt 85 0.60 43.64 13.68 50.00
8 INT22213 Localization of Gpt 52 0.78 34.05 12.94 50.00
9 INT80657 Gene_expression of SLC17A5 50 0.75 39.98 5.44 50.00
10 INT12595 Positive_regulation of LPO 14 0.70 4.92 3.47 50.00
11 INT80656 Regulation of SLC17A5 15 0.26 6.89 3.19 50.00
12 INT92388 Gene_expression of ALK 16 0.78 22.46 2.26 50.00
13 INT70207 Gene_expression of LPO 4 0.75 3.99 1.44 50.00
14 INT184418 Negative_regulation of Positive_regulation of GOPC 15 0.26 5.47 0.87 50.00
15 INT1869 Negative_regulation of SLC17A5 12 0.42 5.51 0.75 50.00
16 INT107118 Positive_regulation of ALK 4 0.49 3.64 0.52 50.00
17 INT165512 Negative_regulation of ALK 2 0.38 1.78 0.29 50.00
18 INT188319 Regulation of Negative_regulation of Gpt 2 0.09 1.91 0.21 50.00
19 INT188330 Regulation of Negative_regulation of SLC17A5 2 0.44 0.51 0.14 50.00
20 INT188326 Regulation of ALK 1 0.01 1.03 0.11 50.00
21 INT188329 Regulation of Negative_regulation of LPO 1 0.26 0.33 0 50.00
22 INT188328 Negative_regulation of LPO 1 0.25 1.02 0 50.00
23 INT188327 Negative_regulation of Positive_regulation of LPO 1 0.24 0.44 0 50.00
24 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 6.24
25 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.88
26 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
27 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41 5.00
28 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 5.00
29 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 5.00
30 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47 5.00
31 INT63934 Phosphorylation of Ephb1 377 0.82 150.52 188.66 5.00
32 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68 5.00
33 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 5.00
34 INT47243 Gene_expression of Prkcg 195 0.78 58.05 108.44 5.00
35 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 5.00
36 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46 5.00
37 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51 5.00
38 INT12763 Phosphorylation of Prkcg 167 0.82 38.91 89.63 5.00
39 INT63936 Positive_regulation of Phosphorylation of Ephb1 131 0.70 49.38 73.16 5.00
40 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 5.00
41 INT39777 Regulation of Prkcg 90 0.62 31.52 68.17 5.00
42 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
43 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 5.00
44 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
45 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 5.00
46 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 5.00
47 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 5.00
48 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78 5.00
49 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63 5.00
50 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
51 INT97702 Positive_regulation of Phosphorylation of Mapk14 69 0.69 49.21 36.81 5.00
52 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98 5.00
53 INT12765 Positive_regulation of Phosphorylation of Prkcg 59 0.66 20.16 34.67 5.00
54 INT95734 Phosphorylation of Mapk8 108 0.82 49.92 33.52 5.00
55 INT51698 Positive_regulation of Gene_expression of Prkcg 44 0.68 14.02 32.9 5.00
56 INT9133 Negative_regulation of Positive_regulation of Prkcg 37 0.59 10.95 30.06 5.00
57 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77 5.00
58 INT20462 Binding of ESR1 210 0.44 102.7 26.34 5.00
59 INT68758 Positive_regulation of Ros1 125 0.46 82.72 25.27 5.00
60 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48 5.00
61 INT10835 Regulation of IL8 79 0.49 53.04 24.14 5.00
62 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7 5.00
63 INT29704 Regulation of Casp3 51 0.56 22.13 22.79 5.00
64 INT99068 Gene_expression of Mapk8 62 0.78 33.57 21.25 5.00
65 INT72060 Positive_regulation of Gene_expression of Ros1 127 0.41 76.76 20.91 5.00
66 INT171820 Localization of Fig4 144 0.65 27.38 20.88 5.00
67 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 5.00
68 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46 5.00
69 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37 5.00
70 INT104493 Negative_regulation of Mapk8 56 0.53 27.76 16.86 5.00
71 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 5.00
72 INT74545 Negative_regulation of Gene_expression of Prkcg 22 0.42 7.77 16.26 5.00
73 INT63854 Regulation of Gene_expression of Prkcg 27 0.56 9.41 14.15 5.00
74 INT95738 Positive_regulation of Phosphorylation of Mapk8 40 0.70 23.46 13.88 5.00
75 INT55343 Localization of Ros1 39 0.60 34.51 12.5 5.00
76 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 5.00
77 INT41313 Gene_expression of Gpx1 68 0.78 34.24 11.77 5.00
78 INT94784 Binding of ROS1 113 0.40 71.57 10.26 5.00
79 INT49660 Positive_regulation of EGR1 54 0.69 32.17 9.89 5.00
80 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51 5.00
81 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28 5.00
82 INT73021 Gene_expression of EGR1 43 0.77 24.65 9.18 5.00
83 INT27551 Gene_expression of SERPINH1 45 0.62 42.87 9.04 5.00
84 INT111998 Positive_regulation of Positive_regulation of Mapk8 23 0.69 9.33 8.97 5.00
85 INT55342 Negative_regulation of Gene_expression of Ros1 49 0.37 31.62 8.93 5.00
86 INT113845 Protein_catabolism of PARP1 54 0.88 43.86 8.77 5.00
87 INT621 Positive_regulation of SERPINH1 19 0.57 21.52 8.44 5.00
88 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37 5.00
89 INT88919 Positive_regulation of Casp9 39 0.70 28.64 8.18 5.00
90 INT126583 Positive_regulation of PARP1 50 0.68 41.44 7.78 5.00
91 INT99071 Positive_regulation of Gene_expression of Mapk8 16 0.55 9.87 7.58 5.00
92 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41 5.00
93 INT67822 Binding of SERPINH1 17 0.36 19.05 7.24 5.00
94 INT75497 Regulation of JUN 28 0.61 11.04 7.09 5.00
95 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71 5.00
96 INT59079 Transcription of PTGS2 30 0.72 14.21 6.52 5.00
97 INT10094 Negative_regulation of ALPP 36 0.37 20.45 6.45 5.00
98 INT99506 Negative_regulation of Bcl2l1 25 0.58 15.7 6.09 5.00
99 INT52311 Positive_regulation of JUNB 12 0.40 4.48 6.02 5.00
100 INT5490 Binding of CA2 52 0.36 9.73 5.53 5.00
101 INT118870 Positive_regulation of STAT1 36 0.67 26.18 5.46 5.00
102 INT128922 Negative_regulation of Gene_expression of Mapk8 6 0.34 3.93 5.36 5.00
103 INT145929 Regulation of Bax 20 0.60 18.12 5.35 5.00
104 INT99507 Positive_regulation of Bcl2l1 17 0.69 9.23 4.97 5.00
105 INT57376 Transcription of EGR1 20 0.69 12.94 4.84 5.00
106 INT11064 Positive_regulation of NPR1 24 0.49 14.63 4.78 5.00
107 INT17110 Gene_expression of PSMD1 60 0.65 19.57 4.69 5.00
108 INT14502 Gene_expression of BCHE 40 0.67 18.52 4.6 5.00
109 INT46121 Negative_regulation of SERPINH1 14 0.38 10.84 4.41 5.00
110 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3 5.00
111 INT57645 Gene_expression of GSTK1 54 0.62 21.05 4.2 5.00
112 INT10992 Gene_expression of PARP1 32 0.76 22.22 3.74 5.00
113 INT81695 Gene_expression of OSM 14 0.75 7.29 3.58 5.00
114 INT74374 Negative_regulation of Phosphorylation of Prkcg 7 0.41 1.28 3.57 5.00
115 INT172852 Localization of Cyct 28 0.78 21.42 3.34 5.00
116 INT163529 Negative_regulation of Positive_regulation of Mapk8 14 0.43 8.37 3.2 5.00
117 INT20006 Gene_expression of MT1F 27 0.68 19.55 3.18 5.00
118 INT187505 Positive_regulation of Localization of Fig4 16 0.24 1.21 3.17 5.00
119 INT130616 Positive_regulation of Negative_regulation of Prkcg 5 0.48 1.6 3.08 5.00
120 INT99508 Regulation of Bcl2l1 12 0.61 10.44 2.71 5.00
121 INT119839 Gene_expression of STAT1 17 0.75 8.36 2.7 5.00
122 INT172853 Positive_regulation of Localization of Cyct 14 0.67 10.48 2.65 5.00
123 INT136424 Gene_expression of DUSP1 9 0.67 4.48 2.64 5.00
124 INT55952 Transcription of TP53 16 0.61 12.14 2.36 5.00
125 INT129280 Gene_expression of Casp9 9 0.68 5.48 2.25 5.00
126 INT156694 Binding of SET 10 0.36 3.77 2.21 5.00
127 INT134442 Transcription of Bax 14 0.67 7.6 1.9 5.00
128 INT10993 Regulation of PARP1 4 0.26 2.04 1.89 5.00
129 INT153800 Positive_regulation of Protein_catabolism of PARP1 18 0.49 16.16 1.89 5.00
130 INT14503 Binding of BCHE 13 0.48 3.95 1.85 5.00
131 INT104883 Positive_regulation of Positive_regulation of Bax 4 0.45 4.05 1.74 5.00
132 INT121964 Positive_regulation of Positive_regulation of Casp9 8 0.32 5.52 1.73 5.00
133 INT127145 Gene_expression of SET 46 0.65 10.39 1.7 5.00
134 INT88916 Negative_regulation of Casp9 5 0.33 3.01 1.67 5.00
135 INT108798 Negative_regulation of Positive_regulation of ALPP 9 0.25 4.26 1.46 5.00
136 INT18495 Regulation of Bad 6 0.19 4.79 1.45 5.00
137 INT49978 Localization of Hbb 4 0.39 1.11 1.29 5.00
138 INT216145 Transcription of IER2 4 0.51 1.52 1.25 5.00
139 INT153125 Negative_regulation of Protein_catabolism of PARP1 8 0.32 6.57 0.98 5.00
140 INT58755 Binding of PAM 6 0.34 3.09 0.97 5.00
141 INT188232 Positive_regulation of OSM 7 0.41 1.57 0.94 5.00
142 INT139839 Positive_regulation of DUSP1 4 0.40 1.79 0.92 5.00
143 INT159668 Positive_regulation of Bad 8 0.45 6.32 0.89 5.00
144 INT127866 Regulation of Gene_expression of Ros1 9 0.22 5.49 0.88 5.00
145 INT151115 Regulation of Regulation of Bcl2 4 0.21 4.12 0.88 5.00
146 INT72151 Phosphorylation of MYOT 2 0.01 1.49 0.88 5.00
147 INT255622 Positive_regulation of PAM 7 0.18 4.89 0.87 5.00
148 INT29636 Localization of PAM 5 0.73 2.1 0.87 5.00
149 INT200900 Localization of Mapk8 9 0.40 5.76 0.84 5.00
150 INT144697 Regulation of Gene_expression of Bax 8 0.37 9.5 0.81 5.00
151 INT187508 Positive_regulation of Localization of Ros1 7 0.15 3.85 0.71 5.00
152 INT126585 Positive_regulation of Positive_regulation of PARP1 3 0.55 2.84 0.56 5.00
153 INT310908 Positive_regulation of Bcl2l11 2 0.38 2.38 0.53 5.00
154 INT323400 Localization of BCHE 1 0.66 1.87 0.46 5.00
155 INT218903 Gene_expression of Bcl2l11 10 0.42 5.19 0.45 5.00
156 INT20007 Regulation of Gene_expression of MT1F 4 0.07 2.35 0.43 5.00
157 INT5223 Negative_regulation of PDP1 8 0.41 1.74 0.37 5.00
158 INT275368 Gene_expression of Cyct 5 0.65 3.21 0.37 5.00
159 INT204069 Negative_regulation of Positive_regulation of Bax 5 0.31 3.08 0.34 5.00
160 INT58409 Negative_regulation of Alad 5 0.43 1.15 0.32 5.00
161 INT222311 Gene_expression of IGKV1-16 4 0.15 4.64 0.3 5.00
162 INT156707 Positive_regulation of SET 6 0.49 1.14 0.26 5.00
163 INT330033 Phosphorylation of Bcl2l11 1 0.30 0.45 0.24 5.00
164 INT159113 Binding of MT1F 5 0.42 1.85 0.23 5.00
165 INT181665 Localization of Apaf1 2 0.49 1.67 0.23 5.00
166 INT330039 Negative_regulation of Positive_regulation of Bcl2l11 1 0.23 1.02 0.19 5.00
167 INT330042 Positive_regulation of Positive_regulation of Bcl2l11 1 0.27 1.02 0.19 5.00
168 INT216144 Positive_regulation of MIR21 4 0.19 2.59 0.19 5.00
169 INT181786 Transcription of JUNB 3 0.59 2.31 0.19 5.00
170 INT177870 Positive_regulation of IER2 3 0.32 0.93 0.17 5.00
171 INT216152 Binding of MTF1 2 0.23 0.41 0.15 5.00
172 INT189390 Positive_regulation of MT1F 5 0.08 0.85 0.14 5.00
173 INT177847 Positive_regulation of MTF1 2 0.29 0.48 0.13 5.00
174 INT120652 Positive_regulation of Alad 2 0.42 1.2 0.12 5.00
175 INT330036 Binding of Apaf1 2 0.25 2.06 0.11 5.00
176 INT148990 Gene_expression of Hrk 2 0.44 2.41 0.11 5.00
177 INT307240 Localization of CYLD 3 0.72 3.09 0.1 5.00
178 INT216142 Transcription of DUSP1 2 0.49 0.06 0.1 5.00
179 INT310906 Regulation of Bcl2l11 2 0.25 2.9 0.1 5.00
180 INT323396 Positive_regulation of VRK1 1 0.12 0.77 0.09 5.00
181 INT291143 Binding of PDP1 3 0.34 0.5 0.08 5.00
182 INT177848 Gene_expression of MTF1 2 0.41 0.46 0.06 5.00
183 INT323397 Regulation of VRK1 1 0.06 0.84 0.05 5.00
184 INT204291 Gene_expression of Apaf1 3 0.42 3.31 0.03 5.00
185 INT315158 Positive_regulation of Cyct 3 0.67 3.03 0.03 5.00
186 INT327509 Binding of Alad 1 0.20 0.54 0.03 5.00
187 INT327512 Positive_regulation of Binding of Alad 1 0.27 0.54 0.03 5.00
188 INT354597 Positive_regulation of Positive_regulation of PAM 1 0.09 1.41 0.03 5.00
189 INT204285 Positive_regulation of Apaf1 2 0.35 1.87 0.03 5.00
190 INT330044 Regulation of Regulation of Bcl2l1 1 0.16 0.76 0 5.00
191 INT155391 Positive_regulation of Negative_regulation of Bcl2 2 0.22 0.92 0 5.00
192 INT323401 Negative_regulation of VRK1 1 0.15 2.64 0 5.00
193 INT330041 Positive_regulation of Regulation of Bax 1 0.29 1.63 0 5.00
194 INT330034 Binding of Cyct 1 0.35 0.95 0 5.00
195 INT330038 Positive_regulation of Gene_expression of Bcl2l11 1 0.38 0.46 0 5.00
196 INT216148 Transcription of SHOC2 1 0.03 0 0 5.00
197 INT327486 Binding of Dpa 1 0.02 1.74 0 5.00
198 INT330037 Regulation of Casp9 1 0.03 0.58 0 5.00
199 INT216143 Transcription of RNF149 1 0.45 0 0 5.00
200 INT216140 Positive_regulation of SRSF5 1 0.35 0 0 5.00
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