D:Arterial-venous Cerebral Malformations

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Arterial Cerebral Malformation, Arterial Venous Cerebral Malformations, Arterial Venous Fistulas Of The Spinal Cord, Arterial Venous Malformations Of The Spinal Cord, Arteriovenous Malformation Cerebral, Arteriovenous Malformation Intracranial, Arteriovenous Malformations Cerebral, Arteriovenous Malformations Intracranial, Avf, Avm, Avm Arteriovenous Malformation Intracranial
Documents 538
Hot Single Events 34
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Arterial-venous Cerebral Malformations. They are ordered first by their relevance to Arterial-venous Cerebral Malformations and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT249159 HSPG2 Positive_regulation of Gene_expression of ITPR3 2 0.01 0.06 0 6.12
2 INT279705 CALM3 Regulation of TRPV4 2 0.08 0 0.33 5.00
3 INT279707 Positive_regulation of AGTR1 Regulation of TYRP1 1 0.00 0 0.09 5.00
4 INT279706 Positive_regulation of AGTR1 Regulation of TRPC6 1 0.00 0 0.09 5.00
5 INT191899 Binding of EXOSC10 and PNN 1 0.00 0.96 0.03 5.00
6 INT275231 Binding of ACVRL1 and AK3 1 0.01 0.72 0 5.00
7 INT279704 Binding of CIB1 and Positive_regulation of ITPR3 1 0.06 0.17 0 5.00
8 INT273886 Binding of Dll1 and Trip12 1 0.34 0.1 0 5.00
9 INT191900 Binding of EXOSC10 and COPD 1 0.01 0.53 0 5.00
10 INT273885 Binding of Mul1 and Cul2 1 0.06 0 0 5.00
11 INT279708 Binding of CA2 and CIB1 1 0.01 0.09 0 5.00
12 INT273887 Binding of Jag1 and Notch2 1 0.02 1.06 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Arterial-venous Cerebral Malformations. They are ordered first by their pain relevance and then by number of times they were reported in Arterial-venous Cerebral Malformations. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT14916 Binding of RASA1 15 0.37 13.64 1.44 100.00
2 INT17993 Negative_regulation of RASA1 8 0.41 7.34 2.62 100.00
3 INT43900 Gene_expression of RASA1 13 0.58 12 2.03 100.00
4 INT7248 Localization of RASA1 4 0.61 2.52 0.47 100.00
5 INT321501 Negative_regulation of Gene_expression of Chgb 1 0.03 0.46 0 100.00
6 INT28970 Gene_expression of Chgb 6 0.75 1.65 2.15 100.00
7 INT247975 Gene_expression of Alm 2 0.07 1.31 0 100.00
8 INT90416 Positive_regulation of RASA1 3 0.67 1.58 0.56 100.00
9 INT12751 Gene_expression of Pigm 91 0.58 22.42 29.2 100.00
10 INT28544 Regulation of Gene_expression of Pigm 6 0.24 1.04 3.96 100.00
11 INT321489 Regulation of Sfpq 1 0.04 0.1 0 100.00
12 INT217070 Gene_expression of Acsm3 8 0.25 6.27 1.75 99.98
13 INT89995 Binding of Rsph1 4 0.29 2.48 0.2 99.76
14 INT2837 Regulation of PAEP 17 0.53 7.84 3.17 99.70
15 INT28802 Binding of F2 15 0.47 8.8 3.47 99.66
16 INT67179 Negative_regulation of Binding of F2 3 0.41 2.23 0.45 99.66
17 INT76869 Localization of PAEP 15 0.73 6.57 3.36 99.64
18 INT179228 Localization of Crisp1 2 0.73 0.9 0.2 99.64
19 INT281987 Gene_expression of Crisp1 2 0.08 1.22 0.1 99.34
20 INT1038 Negative_regulation of F2 26 0.58 15.12 6.75 99.24
21 INT939 Gene_expression of PAEP 86 0.77 31.02 8.59 99.18
22 INT195285 Gene_expression of Ttc21b 4 0.37 1.52 0.15 98.60
23 INT195363 Gene_expression of AQR 1 0.10 3.5 0 98.00
24 INT4207 Regulation of Avp 267 0.62 63.72 115.33 95.16
25 INT23147 Negative_regulation of MRI1 26 0.38 14.33 8.96 94.84
26 INT161202 Binding of Tg(Fst)4Zuk 1 0.26 0.85 0.23 94.80
27 INT239909 Gene_expression of Pdf 1 0.05 0.37 0 94.56
28 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 91.28
29 INT147583 Gene_expression of AIS 82 0.58 48.7 7.11 88.24
30 INT195364 Binding of AQR 1 0.04 1.17 0.03 88.24
31 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28 87.28
32 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 82.72
33 INT438 Gene_expression of Crh 376 0.78 159.11 169.17 81.76
34 INT111032 Binding of ACOT8 1 0.36 1.51 0.18 80.32
35 INT129312 Gene_expression of SGCB 24 0.76 18.25 3.75 78.16
36 INT334815 Binding of Artles 1 0.00 1.22 0.14 75.60
37 INT11072 Binding of HELT 4 0.31 3.81 0.89 75.44
38 INT314 Positive_regulation of Ren 212 0.70 66.68 55.56 75.00
39 INT49 Negative_regulation of Ren 129 0.59 37.48 35.62 75.00
40 INT1815 Positive_regulation of Negative_regulation of Ren 6 0.47 1.32 2.54 75.00
41 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43 70.40
42 INT7469 Positive_regulation of Gene_expression of Oxt 18 0.59 4.7 14.36 70.40
43 INT5941 Gene_expression of Oxt 164 0.76 22.63 65.47 70.00
44 INT1898 Regulation of Crh 220 0.62 61.33 102.64 69.92
45 INT42459 Positive_regulation of Gene_expression of Pag1 19 0.25 13.49 12.22 69.00
46 INT1351 Gene_expression of Pag1 131 0.57 89.48 98.76 68.40
47 INT12194 Gene_expression of Trf 38 0.69 18.1 4.56 66.56
48 INT28308 Localization of SLC17A5 10 0.73 6.77 0.7 59.16
49 INT21379 Transcription of Crh 65 0.72 15.64 27.92 57.28
50 INT440 Regulation of Gene_expression of Crh 44 0.62 17.71 20.73 57.28
51 INT5499 Transcription of Avp 52 0.72 7.98 19.87 57.28
52 INT13743 Regulation of Gene_expression of Avp 30 0.62 6.9 11.66 57.28
53 INT21380 Regulation of Transcription of Avp 10 0.62 2.6 5.46 57.28
54 INT3244 Negative_regulation of eCB 37 0.03 16.69 12.61 49.28
55 INT129058 Binding of Arid3a 2 0.34 0.95 0.09 49.20
56 INT321488 Gene_expression of Sfpq 1 0.05 0 0 44.32
57 INT26919 Gene_expression of ITPR3 47 0.42 5.86 5.79 38.44
58 INT27534 Negative_regulation of Gba 10 0.57 6.23 0.38 27.52
59 INT30443 Positive_regulation of AIS 30 0.54 22.59 7.2 22.64
60 INT255313 Positive_regulation of Positive_regulation of AIS 2 0.04 3.83 0.55 22.64
61 INT33706 Regulation of ITPR3 6 0.28 0.46 0.3 16.60
62 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 14.56
63 INT9220 Gene_expression of Ighg1 125 0.77 85.74 15.92 14.56
64 INT39416 Gene_expression of Cd79a 81 0.64 45.17 6.08 14.56
65 INT184006 Gene_expression of Ighg2b 21 0.71 7.97 1.86 14.56
66 INT68247 Gene_expression of Ighg3 6 0.65 1.76 0.79 14.56
67 INT2836 Positive_regulation of PAEP 51 0.67 26.69 4.57 14.40
68 INT179227 Positive_regulation of Crisp1 3 0.45 1.15 0.3 14.40
69 INT239496 Gene_expression of Aes 4 0.52 1.45 0.76 6.00
70 INT62887 Regulation of Gene_expression of ITPR3 3 0.14 0.95 0.76 5.64
71 INT14447 Localization of F2 20 0.79 12.77 2.67 5.16
72 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 5.00
73 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 5.00
74 INT1114 Localization of Ins1 748 0.80 192.95 165.48 5.00
75 INT6323 Positive_regulation of Gabrg1 213 0.70 45.08 124.34 5.00
76 INT89054 Positive_regulation of Gene_expression of Trpv1 156 0.70 90.78 102.03 5.00
77 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
78 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 5.00
79 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 5.00
80 INT2276 Regulation of Ins1 234 0.61 103.78 54.05 5.00
81 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97 5.00
82 INT58062 Negative_regulation of Gene_expression of Trpv1 66 0.59 22.34 38.02 5.00
83 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 5.00
84 INT5489 Localization of CA2 172 0.80 39.46 33.56 5.00
85 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22 5.00
86 INT8691 Localization of Insr 85 0.80 9.27 30.32 5.00
87 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
88 INT72370 Gene_expression of Timp1 82 0.65 57.52 24.16 5.00
89 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 5.00
90 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 5.00
91 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
92 INT125312 Positive_regulation of COPD 134 0.59 162.55 20.27 5.00
93 INT23533 Gene_expression of CA2 110 0.75 30.81 19.4 5.00
94 INT70970 Binding of COPD 144 0.42 180.34 18.29 5.00
95 INT17313 Positive_regulation of HSPG2 57 0.67 55.78 16.65 5.00
96 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 5.00
97 INT2630 Positive_regulation of Shbg 134 0.70 65.26 15.19 5.00
98 INT2758 Binding of Dbp 36 0.44 8.3 14.47 5.00
99 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 5.00
100 INT50056 Positive_regulation of Dll1 13 0.67 3.16 13.7 5.00
101 INT3602 Negative_regulation of Shbg 148 0.53 69.05 11.65 5.00
102 INT9945 Negative_regulation of Csf2 35 0.51 17.85 11.22 5.00
103 INT11238 Positive_regulation of ADA 33 0.70 39.7 9.98 5.00
104 INT56019 Gene_expression of Dll1 11 0.78 3.38 8.71 5.00
105 INT8637 Negative_regulation of Dbp 112 0.50 33.28 8.4 5.00
106 INT197447 Negative_regulation of Psmd1 12 0.33 4.33 7.66 5.00
107 INT76892 Gene_expression of FGFR1 45 0.69 23.6 7.56 5.00
108 INT11823 Positive_regulation of GGT1 53 0.67 45.84 7.55 5.00
109 INT58607 Negative_regulation of Dll1 9 0.43 1.89 7.06 5.00
110 INT32709 Negative_regulation of Hbb 30 0.54 18.27 6.97 5.00
111 INT195145 Positive_regulation of Gene_expression of CA2 25 0.37 7.2 6.59 5.00
112 INT25022 Binding of PAEP 66 0.42 22.83 6.59 5.00
113 INT70287 Positive_regulation of Gene_expression of Dll1 6 0.70 3.58 6.55 5.00
114 INT24042 Gene_expression of MUC5AC 98 0.77 74.99 6.18 5.00
115 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02 5.00
116 INT149385 Positive_regulation of TRPV4 11 0.69 7.22 6.02 5.00
117 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65 5.00
118 INT21103 Gene_expression of Dbp 48 0.61 22.6 5.59 5.00
119 INT5490 Binding of CA2 52 0.36 9.73 5.53 5.00
120 INT102891 Positive_regulation of AGTR1 31 0.67 30.57 5.29 5.00
121 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22 5.00
122 INT68202 Gene_expression of ADA 26 0.68 23.15 5.18 5.00
123 INT68591 Regulation of TYRP1 14 0.44 3.93 5.05 5.00
124 INT8773 Gene_expression of HBG1 58 0.76 37.6 4.59 5.00
125 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41 5.00
126 INT4683 Negative_regulation of PDXK 17 0.55 12.81 4.39 5.00
127 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91 5.00
128 INT179542 Positive_regulation of C3 27 0.52 19.39 3.83 5.00
129 INT26191 Positive_regulation of ITPR3 24 0.44 1.9 3.74 5.00
130 INT106618 Positive_regulation of CIB1 9 0.63 3.38 3.63 5.00
131 INT19211 Binding of Shbg 35 0.48 16.29 3.31 5.00
132 INT134786 Gene_expression of Adam10 17 0.68 7.61 3.29 5.00
133 INT55409 Localization of VWF 17 0.80 8.99 3.06 5.00
134 INT55148 Binding of Dll1 5 0.48 0.66 2.97 5.00
135 INT131494 Regulation of ADA 8 0.52 7.37 2.97 5.00
136 INT184365 Negative_regulation of C3 19 0.43 13.86 2.89 5.00
137 INT139872 Regulation of Notch1 14 0.45 7.69 2.82 5.00
138 INT175685 Positive_regulation of Gene_expression of Timp1 11 0.57 8.18 2.58 5.00
139 INT142908 Localization of FGFR1 18 0.38 11.46 2.57 5.00
140 INT94010 Positive_regulation of Localization of VWF 9 0.70 4.23 2.5 5.00
141 INT26335 Binding of ITPR3 22 0.18 3.3 2.27 5.00
142 INT108710 Gene_expression of HAL 36 0.58 14.75 2.16 5.00
143 INT50057 Regulation of Notch1 3 0.39 0.87 2.14 5.00
144 INT140036 Positive_regulation of Gene_expression of Notch1 6 0.61 2 1.86 5.00
145 INT120505 Negative_regulation of ITPR3 6 0.27 1.46 1.68 5.00
146 INT57785 Positive_regulation of SGCB 25 0.69 5.01 1.49 5.00
147 INT2824 Positive_regulation of HTN1 10 0.40 10.41 1.4 5.00
148 INT16239 Negative_regulation of Trf 9 0.32 4.06 1.35 5.00
149 INT110784 Protein_catabolism of Notch1 8 0.21 2.32 1.31 5.00
150 INT110434 Positive_regulation of Gene_expression of Apc 20 0.50 11.37 1.3 5.00
151 INT100051 Binding of MUC5AC 20 0.32 14.21 1.14 5.00
152 INT192073 Positive_regulation of Gene_expression of ADA 8 0.47 10.35 1.12 5.00
153 INT135527 Negative_regulation of Gene_expression of Cd4 17 0.43 6.72 1.09 5.00
154 INT61643 Gene_expression of ACVRL1 9 0.51 9.04 1.03 5.00
155 INT82687 Gene_expression of Arsi 4 0.57 2.6 0.97 5.00
156 INT61642 Binding of ACVRL1 5 0.31 7.03 0.87 5.00
157 INT129797 Negative_regulation of Binding of ITPR3 3 0.14 0.58 0.75 5.00
158 INT129756 Regulation of MUC5AC 7 0.34 6.45 0.7 5.00
159 INT139089 Negative_regulation of Gene_expression of Dll1 2 0.43 0 0.69 5.00
160 INT140037 Positive_regulation of Positive_regulation of Notch1 2 0.22 1.34 0.69 5.00
161 INT191905 Binding of EXOSC10 19 0.04 11.24 0.57 5.00
162 INT191904 Positive_regulation of EXOSC10 11 0.06 5.43 0.57 5.00
163 INT201307 Negative_regulation of Vcan 4 0.41 1.71 0.43 5.00
164 INT242267 Localization of Slc25a16 1 0.34 6.15 0.43 5.00
165 INT60035 Regulation of VWF 6 0.42 6.26 0.4 5.00
166 INT195362 Positive_regulation of AQR 1 0.09 2.33 0.36 5.00
167 INT231102 Gene_expression of Mul1 8 0.21 1.66 0.35 5.00
168 INT38824 Positive_regulation of CABP1 3 0.56 0.08 0.34 5.00
169 INT246100 Positive_regulation of Gene_expression of Adam10 4 0.61 1.2 0.3 5.00
170 INT273867 Binding of Jag1 18 0.45 3.14 0.25 5.00
171 INT201308 Binding of Vcan 5 0.34 1.05 0.24 5.00
172 INT195366 Negative_regulation of AQR 1 0.06 1.06 0.23 5.00
173 INT238020 Gene_expression of Tspan31 3 0.65 0.66 0.2 5.00
174 INT193945 Binding of Notch1 7 0.15 1.28 0.19 5.00
175 INT279733 Regulation of Regulation of TYRP1 1 0.01 0 0.18 5.00
176 INT242268 Binding of Slc25a16 1 0.17 1.67 0.15 5.00
177 INT348287 Binding of Dgkb 1 0.35 0.27 0.12 5.00
178 INT249285 Regulation of TRPC6 2 0.36 0 0.09 5.00
179 INT191908 Negative_regulation of Positive_regulation of EXOSC10 1 0.01 0.25 0.09 5.00
180 INT273866 Binding of Mul1 4 0.11 0.69 0.09 5.00
181 INT191906 Positive_regulation of Positive_regulation of EXOSC10 2 0.04 0.66 0.07 5.00
182 INT321500 Binding of Crisp1 1 0.03 0 0.04 5.00
183 INT249235 Positive_regulation of Binding of ITPR3 3 0.17 0.2 0.03 5.00
184 INT273854 Gene_expression of Trip12 1 0.63 0.08 0 5.00
185 INT273863 Binding of Trip12 1 0.39 0.1 0 5.00
186 INT163773 Gene_expression of Cth 2 0.64 0.29 0 5.00
187 INT273856 Gene_expression of Siah1a 1 0.08 0.28 0 5.00
188 INT195365 Localization of AQR 1 0.09 0.87 0 5.00
189 INT191907 Positive_regulation of Binding of EXOSC10 1 0.01 0.36 0 5.00
190 INT273843 Regulation of Ddx6 1 0.37 0 0 5.00
191 INT273855 Negative_regulation of Idi1 1 0.49 0 0 5.00
192 INT273847 Positive_regulation of Siah1a 1 0.06 0.3 0 5.00
193 INT273857 Transcription of Bhmt 1 0.64 0.15 0 5.00
194 INT273844 Negative_regulation of Serpina3k 1 0.38 0 0 5.00
195 INT273839 Binding of Cul2 1 0.18 0 0 5.00
196 INT273849 Positive_regulation of Trbv31 1 0.15 0 0 5.00
197 INT273853 Positive_regulation of Gene_expression of Siah1a 1 0.06 0.3 0 5.00
198 INT273841 Negative_regulation of Ywhab 1 0.32 0.05 0 5.00
199 INT321499 Binding of Chgb 1 0.03 0 0 5.00
200 INT273846 Negative_regulation of Serpina3c 1 0.38 0 0 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox