D:Arterial Occlusive Diseases

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Disease Term
Synonyms ARTERIAL OBSTRUCTIVE DISEASE, Arterial Obstructive Diseases, Arterial Occlusive Disease, DISEASE ARTERIAL OBSTRUCTIVE, DISEASE ARTERIAL OCCLUSIVE, Diseases Arterial Obstructive, Diseases Arterial Occlusive, Obstructive Disease Arterial, Obstructive Diseases Arterial, Occlusive Disease Arterial, Occlusive Diseases Arterial
Documents 243
Hot Single Events 24
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Arterial Occlusive Diseases. They are ordered first by their relevance to Arterial Occlusive Diseases and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT118838 Gene_expression of Vegfa Positive_regulation of Gene_expression of Mb 1 0.44 0.4 0.22 94.44
2 INT118840 VEGFA Regulation of Positive_regulation of Mb 1 0.05 0.36 0.23 89.84
3 INT118839 VEGFA Positive_regulation of Mb 1 0.13 0.15 0.03 44.84
4 INT241853 Binding of SLC40A1 and HAMP 3 0.41 5.35 0.43 5.00
5 INT179968 GBE1 Negative_regulation of IK 1 0.00 0.3 0.25 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Arterial Occlusive Diseases. They are ordered first by their pain relevance and then by number of times they were reported in Arterial Occlusive Diseases. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT83188 Binding of PAOD1 2 0.29 1.15 0.51 100.00
2 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 97.96
3 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 97.76
4 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 97.68
5 INT118835 Positive_regulation of Vegfa 18 0.59 11.2 3.91 97.44
6 INT11359 Gene_expression of PLAU 84 0.76 49.54 12.31 96.80
7 INT27832 Positive_regulation of Ak1 5 0.46 0.96 0.77 96.28
8 INT118837 Gene_expression of Mb 7 0.74 2.72 0.4 94.44
9 INT145758 Regulation of Tlr2 3 0.43 0.94 0.23 92.72
10 INT143159 Regulation of Gene_expression of TLR4 28 0.62 15.08 3.54 92.72
11 INT145759 Regulation of Gene_expression of Tlr2 3 0.43 0.98 0.14 92.72
12 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89 92.12
13 INT118833 Positive_regulation of Gene_expression of Vegfa 11 0.65 8.14 1.7 92.12
14 INT145756 Gene_expression of Tlr2 23 0.74 20.77 5.18 90.48
15 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 90.12
16 INT145768 Regulation of TLR4 19 0.45 8.31 2.96 90.12
17 INT13354 Transcription of TNF 108 0.72 85.81 42.32 88.64
18 INT118834 Positive_regulation of Mb 6 0.66 1.68 0.79 87.92
19 INT55409 Localization of VWF 17 0.80 8.99 3.06 85.28
20 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 84.88
21 INT60034 Positive_regulation of VWF 40 0.68 30.42 8.15 84.88
22 INT59302 Positive_regulation of POR 19 0.49 15.18 1.95 83.64
23 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 83.60
24 INT24684 Localization of PLAT 30 0.78 26.21 13.56 82.92
25 INT134651 Binding of TLR4 89 0.48 66.96 23.19 77.92
26 INT145760 Binding of Tlr2 5 0.46 3.59 0.89 77.92
27 INT9660 Regulation of TNF 363 0.62 312.94 139.99 75.00
28 INT2378 Negative_regulation of SERPINE1 47 0.59 34.55 9.9 75.00
29 INT1755 Gene_expression of GBE1 28 0.26 8.32 5.18 75.00
30 INT44832 Gene_expression of Tcn2 2 0.28 0.75 0.27 75.00
31 INT14404 Negative_regulation of SERPINF2 11 0.47 3.15 1.47 70.68
32 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67 66.72
33 INT16644 Positive_regulation of Plg 16 0.60 6.38 3.62 59.56
34 INT145767 Negative_regulation of TLR4 18 0.43 11.03 5.25 56.88
35 INT145761 Negative_regulation of Tlr2 2 0.41 1.97 0.23 56.88
36 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 56.36
37 INT100275 Gene_expression of TBL1XR1 19 0.25 6.99 1.33 51.88
38 INT204363 Gene_expression of VIS1 6 0.19 2.49 0.21 51.68
39 INT3755 Positive_regulation of GBE1 29 0.40 8.99 8.91 50.20
40 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 48.88
41 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 47.88
42 INT145757 Negative_regulation of Gene_expression of Tlr2 2 0.41 0.68 0.03 46.56
43 INT57138 Binding of Hdlcl1 13 0.30 18.51 0.64 45.20
44 INT299966 Negative_regulation of EPC1 10 0.22 8.66 1.07 44.00
45 INT118836 Positive_regulation of Gene_expression of Mb 1 0.66 0.15 0.03 41.92
46 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 40.24
47 INT10888 Binding of Vwf 32 0.46 22.87 5.21 35.92
48 INT11859 Positive_regulation of Tbxa2r 44 0.61 22.62 9.61 30.08
49 INT32107 Gene_expression of PTPLA 14 0.47 8.06 6.76 21.96
50 INT45612 Negative_regulation of pad 8 0.37 6.74 2.57 11.68
51 INT274724 Positive_regulation of TBL1XR1 5 0.12 2.74 0.45 9.28
52 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
53 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
54 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
55 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
56 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
57 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
58 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
59 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
60 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
61 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 5.00
62 INT6849 Localization of IL1B 229 0.81 112.56 69.63 5.00
63 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 5.00
64 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 5.00
65 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 5.00
66 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
67 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 5.00
68 INT17381 Gene_expression of Tbxa2r 146 0.78 65.01 34.15 5.00
69 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
70 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92 5.00
71 INT112174 Gene_expression of Trpv4 47 0.78 26.26 20.09 5.00
72 INT69952 Positive_regulation of IK 45 0.32 16.08 14.59 5.00
73 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 5.00
74 INT39712 Binding of pad 82 0.48 110.92 10.33 5.00
75 INT7105 Gene_expression of pad 54 0.77 63.68 8.8 5.00
76 INT73558 Regulation of IK 23 0.23 12.02 8.73 5.00
77 INT19829 Negative_regulation of Gene_expression of Tbxa2r 32 0.56 12.78 8.3 5.00
78 INT124702 Positive_regulation of Trpv4 21 0.69 7.14 8.2 5.00
79 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 5.00
80 INT32458 Gene_expression of VWF 57 0.78 28.97 5.56 5.00
81 INT64888 Negative_regulation of HBM 52 0.16 34.33 5.45 5.00
82 INT8773 Gene_expression of HBG1 58 0.76 37.6 4.59 5.00
83 INT21681 Positive_regulation of CD34 54 0.66 33.95 4.14 5.00
84 INT11261 Positive_regulation of PTPLA 3 0.50 4.4 3.74 5.00
85 INT78284 Positive_regulation of PTPRC 40 0.49 27.17 3.45 5.00
86 INT139366 Gene_expression of PROM1 98 0.77 67.84 3.39 5.00
87 INT71794 Binding of SERPINC1 17 0.39 10.5 2.64 5.00
88 INT39560 Positive_regulation of F10 25 0.67 10.67 2.5 5.00
89 INT230758 Positive_regulation of Gene_expression of PTPRC 11 0.49 6.04 2.45 5.00
90 INT52357 Gene_expression of Sub1 6 0.16 2.49 2.25 5.00
91 INT12131 Gene_expression of POR 17 0.77 9.42 2.17 5.00
92 INT7106 Regulation of pad 8 0.27 5.24 2.16 5.00
93 INT55106 Positive_regulation of Sub1 8 0.20 3.81 1.93 5.00
94 INT149153 Positive_regulation of Gene_expression of Trpv4 12 0.70 3.37 1.72 5.00
95 INT30886 Positive_regulation of Ina 5 0.62 1.35 0.96 5.00
96 INT24266 Negative_regulation of IKZF1 6 0.37 1.55 0.96 5.00
97 INT215897 Gene_expression of Mcam 10 0.75 4.68 0.81 5.00
98 INT156175 Positive_regulation of Positive_regulation of Trpv4 5 0.50 0.86 0.8 5.00
99 INT101091 Regulation of IKZF1 3 0.09 0.3 0.79 5.00
100 INT176489 Gene_expression of MCAM 18 0.68 3.92 0.78 5.00
101 INT88957 Positive_regulation of Gene_expression of VWF 12 0.42 7.34 0.75 5.00
102 INT274725 Regulation of TBL1XR1 5 0.11 2.08 0.64 5.00
103 INT216873 Binding of TBL1XR1 3 0.36 4.44 0.4 5.00
104 INT201695 Positive_regulation of TIAF1 3 0.08 2.39 0.38 5.00
105 INT186453 Gene_expression of TAB1 6 0.65 4.83 0.35 5.00
106 INT179967 Regulation of Ina 2 0.38 0.32 0.28 5.00
107 INT100277 Positive_regulation of Gene_expression of TBL1XR1 5 0.19 1.9 0.25 5.00
108 INT243267 Positive_regulation of SLC40A1 4 0.41 2.72 0.22 5.00
109 INT241863 Binding of SLC40A1 4 0.28 3.86 0.22 5.00
110 INT156172 Transcription of Trpv4 3 0.72 1.19 0.19 5.00
111 INT243268 Gene_expression of SLC40A1 6 0.60 4.18 0.13 5.00
112 INT156173 Positive_regulation of Transcription of Trpv4 1 0.61 0.43 0.1 5.00
113 INT156174 Positive_regulation of Gene_expression of Sub1 1 0.01 0.47 0.08 5.00
114 INT67606 Localization of POR 3 0.68 1.22 0.06 5.00
115 INT274745 Localization of TAB1 2 0.45 0.74 0.04 5.00
116 INT184625 Localization of Skap2 4 0.62 0.5 0.03 5.00
117 INT311026 Positive_regulation of Mcam 2 0.49 0.3 0.03 5.00
118 INT323616 Phosphorylation of POR 1 0.05 0.7 0 5.00
119 INT323617 Positive_regulation of Phosphorylation of POR 1 0.03 0.7 0 5.00
120 INT274747 Regulation of COX1 1 0.26 0.1 0 5.00
121 INT274746 Regulation of Gene_expression of TBL1XR1 1 0.02 0.41 0 5.00
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