D:Astigmatism

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms None
Documents 107
Hot Single Events 10
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Astigmatism. They are ordered first by their relevance to Astigmatism and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT301044 Binding of Csn2 and Trpm1 1 0.09 2.17 0.03 65.12
2 INT213824 Binding of PDB1 and ANTXR2 1 0.16 0 0 37.96
3 INT301043 P9Ehs1 Regulation of Trpv1 1 0.00 0.06 0.1 5.00
4 INT301041 Grm6 Regulation of Trpv1 1 0.00 0.06 0.1 5.00
5 INT329015 Binding of APCS and SRGN 1 0.08 1.14 0.04 5.00
6 INT301042 Binding of Csn2 and Nyx 1 0.07 0.51 0 5.00
7 INT273136 Binding of CHED1 and VSX1 1 0.15 0.12 0 5.00
8 INT289426 Binding of ESR1 and RXFP1 1 0.01 0.18 0 5.00
9 INT301045 Binding of Csn2 and Grm6 1 0.02 0.51 0 5.00
10 INT301046 Binding of BCS1L and Csn2 1 0.01 0.62 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Astigmatism. They are ordered first by their pain relevance and then by number of times they were reported in Astigmatism. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT308257 Positive_regulation of Gene_expression of SIM2 1 0.24 7.45 0 100.00
2 INT272309 Negative_regulation of Atr 1 0.24 2.26 0 100.00
3 INT304967 Gene_expression of SIM2 2 0.55 3.58 0 100.00
4 INT308255 Negative_regulation of SIM2 1 0.18 1.11 0 99.96
5 INT308256 Positive_regulation of SIM2 1 0.24 1.27 0 99.16
6 INT70625 Gene_expression of epi 3 0.59 1.54 1.12 95.72
7 INT192084 Positive_regulation of Atr 4 0.40 0.83 0.17 90.56
8 INT314365 Binding of epi 1 0.03 4.91 2.7 87.28
9 INT23994 Positive_regulation of epi 5 0.64 1.65 2.15 87.28
10 INT346922 Transcription of NFIC 1 0.18 0.81 0 86.24
11 INT1982 Regulation of NARFL 119 0.49 116.2 14.35 79.40
12 INT110988 Gene_expression of Insr 58 0.42 42.12 12.18 79.08
13 INT154636 Gene_expression of Prkra 1 0.58 0.57 0.13 77.84
14 INT346921 Negative_regulation of NFIC 1 0.11 1.9 0 74.04
15 INT131456 Negative_regulation of MMRN1 14 0.19 9.49 2.29 71.72
16 INT131378 Negative_regulation of FN1 20 0.35 33.98 5.85 71.40
17 INT201216 Negative_regulation of LAMB2 6 0.04 3.75 0.71 71.40
18 INT230969 Negative_regulation of COL4A4 3 0.14 2.66 0.16 71.40
19 INT42632 Negative_regulation of epi 4 0.42 0.84 0.98 69.72
20 INT179337 Positive_regulation of Gene_expression of Ecm1 14 0.05 3.73 0.58 68.28
21 INT134967 Gene_expression of Ecm1 66 0.29 38.4 7.16 67.80
22 INT346650 Gene_expression of PLK3 1 0.47 1.48 0 67.32
23 INT286356 Positive_regulation of Gene_expression of KRT12 1 0.50 0.42 0 65.96
24 INT159614 Gene_expression of Trpm1 13 0.77 9.47 1.25 65.92
25 INT225958 Gene_expression of KRT12 13 0.68 1.57 0 65.08
26 INT265331 Gene_expression of Tnmd 6 0.30 0.06 0.28 64.72
27 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 64.24
28 INT346651 Gene_expression of Tsv 1 0.10 0.59 0.06 58.80
29 INT189629 Negative_regulation of TIMP3 14 0.48 7.63 3.91 56.84
30 INT27446 Negative_regulation of CTSA 11 0.57 5.58 3.08 56.84
31 INT2384 Regulation of CTSA 4 0.44 2.22 0.69 46.48
32 INT22781 Binding of COL7A1 76 0.48 41.59 6.66 44.92
33 INT1981 Negative_regulation of NARFL 219 0.47 223.48 16.41 44.32
34 INT346648 Regulation of Transcription of SERINC1 1 0.18 1.21 0 41.68
35 INT94173 Positive_regulation of CTSA 3 0.53 3.22 0.4 41.00
36 INT286355 Negative_regulation of KRTAP1-1 1 0.05 0.06 0 40.48
37 INT346647 Transcription of SERINC1 1 0.27 1.19 0 40.04
38 INT99966 Negative_regulation of Positive_regulation of NARFL 13 0.37 13.32 0.98 33.56
39 INT272415 Negative_regulation of Gene_expression of NARFL 14 0.34 17.62 0.73 33.56
40 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 33.12
41 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 33.12
42 INT272273 Gene_expression of NARFL 89 0.54 121.19 4.47 32.84
43 INT10870 Regulation of IgG 67 0.59 43.27 12.74 32.16
44 INT52907 Regulation of Gene_expression of HLA-DRA 28 0.34 5.94 5.96 32.16
45 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 31.60
46 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 31.32
47 INT301034 Regulation of Olfr624 1 0.01 0.13 0 29.20
48 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42 28.84
49 INT301035 Localization of Trpm1 1 0.80 2.46 0.37 27.60
50 INT301038 Localization of Olfr624 1 0.01 0.12 0 26.24
51 INT272272 Positive_regulation of Gene_expression of NARFL 17 0.40 18.85 0.31 25.88
52 INT92678 Positive_regulation of Ecm1 30 0.09 28.41 3.68 24.16
53 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 19.44
54 INT134968 Localization of Ecm1 20 0.32 27.27 4.31 18.48
55 INT248774 Positive_regulation of Localization of Ecm1 4 0.05 8.46 0.92 18.48
56 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 16.52
57 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7 16.52
58 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 16.12
59 INT259471 Localization of LAMA3 1 0.52 0.76 0.03 14.44
60 INT272274 Localization of NARFL 24 0.60 27.55 1.18 13.28
61 INT118430 Positive_regulation of Gene_expression of VIM 8 0.47 2.14 1.53 8.80
62 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 8.00
63 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 5.00
64 INT1114 Localization of Ins1 748 0.80 192.95 165.48 5.00
65 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
66 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 5.00
67 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
68 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7 5.00
69 INT98621 Regulation of Trpv1 121 0.62 79.24 75.23 5.00
70 INT253 Regulation of PRL 184 0.62 47.27 65.79 5.00
71 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
72 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 5.00
73 INT60710 Gene_expression of Col7a1 217 0.78 113.2 35.2 5.00
74 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96 5.00
75 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 5.00
76 INT20462 Binding of ESR1 210 0.44 102.7 26.34 5.00
77 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66 5.00
78 INT22068 Binding of CALCRL 53 0.41 6.14 17.32 5.00
79 INT11508 Positive_regulation of TGFBI 24 0.70 19.81 15.78 5.00
80 INT42810 Gene_expression of CALCRL 53 0.77 10.87 15.42 5.00
81 INT8629 Positive_regulation of COL7A1 72 0.69 40.66 12.09 5.00
82 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 5.00
83 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55 5.00
84 INT77877 Regulation of P9Ehs1 13 0.38 3.31 10.04 5.00
85 INT22481 Gene_expression of CADM1 28 0.65 30.26 8.5 5.00
86 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29 5.00
87 INT89048 Gene_expression of P2RX2 28 0.75 8.75 7.9 5.00
88 INT53189 Gene_expression of VSX1 32 0.69 10.59 7.21 5.00
89 INT50419 Gene_expression of Grina 13 0.25 6.11 6.42 5.00
90 INT55655 Gene_expression of DCN 17 0.75 7.98 5.98 5.00
91 INT95759 Gene_expression of DIO3 5 0.51 2.55 5.28 5.00
92 INT25831 Gene_expression of NR4A2 20 0.74 2.73 4.92 5.00
93 INT83837 Gene_expression of CEACAM6 7 0.76 13.8 4.59 5.00
94 INT44066 Gene_expression of Ltf 20 0.77 15.09 4.57 5.00
95 INT23045 Positive_regulation of Hbb 31 0.64 19.35 4.54 5.00
96 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12 5.00
97 INT52678 Positive_regulation of VSX1 15 0.42 3.94 3.64 5.00
98 INT5204 Positive_regulation of Gene_expression of AR 60 0.67 23.54 3.53 5.00
99 INT5286 Gene_expression of ANTXR2 46 0.75 21.06 3.41 5.00
100 INT2117 Regulation of VSX1 15 0.30 3.38 3.38 5.00
101 INT4596 Positive_regulation of SCD 18 0.42 22.59 3.26 5.00
102 INT44873 Negative_regulation of LCAT 16 0.59 6.92 3.13 5.00
103 INT37590 Regulation of COL7A1 15 0.54 9.4 3.12 5.00
104 INT168188 Gene_expression of PLXNA2 13 0.58 9 2.73 5.00
105 INT60765 Gene_expression of LAMB2 28 0.49 13.93 2.38 5.00
106 INT18853 Negative_regulation of APCS 13 0.57 4.51 2.3 5.00
107 INT92835 Gene_expression of Col4a1 22 0.49 13.5 2.27 5.00
108 INT132903 Gene_expression of Cd34 65 0.72 33.95 2.2 5.00
109 INT2116 Negative_regulation of VSX1 29 0.36 10.67 1.89 5.00
110 INT85084 Gene_expression of KRT19 66 0.73 42.56 1.82 5.00
111 INT121335 Localization of SCD 10 0.68 6.81 1.51 5.00
112 INT22871 Gene_expression of ELN 30 0.68 14.86 1.33 5.00
113 INT248975 Positive_regulation of Csn2 4 0.10 0.66 1.31 5.00
114 INT126370 Localization of VSX1 6 0.56 1.7 1.28 5.00
115 INT1787 Binding of Antxr1 13 0.32 2.62 1.22 5.00
116 INT112498 Gene_expression of TGM1 18 0.55 10.76 1.21 5.00
117 INT159618 Transcription of Trpm1 8 0.69 11.42 1.21 5.00
118 INT105571 Gene_expression of SRGN 33 0.58 14.68 1.19 5.00
119 INT28083 Negative_regulation of Gene_expression of VIM 9 0.41 7.23 1.17 5.00
120 INT60766 Gene_expression of COL4A4 10 0.77 13.46 1.14 5.00
121 INT121788 Localization of BCS1L 11 0.73 10.16 1.14 5.00
122 INT133102 Negative_regulation of Gene_expression of COL1A2 8 0.08 2.56 1.02 5.00
123 INT83835 Positive_regulation of CEACAM6 3 0.24 1.53 1.01 5.00
124 INT83834 Transcription of CEACAM6 2 0.28 0.1 0.93 5.00
125 INT3776 Positive_regulation of Regulation of NARFL 2 0.37 2.44 0.93 5.00
126 INT39369 Binding of NARFL 14 0.29 16.7 0.93 5.00
127 INT57059 Negative_regulation of IGKC 4 0.24 1.34 0.86 5.00
128 INT157846 Gene_expression of BCS1L 13 0.50 15.89 0.83 5.00
129 INT216734 Regulation of Matn1 2 0.26 0 0.77 5.00
130 INT231685 Binding of CD47 12 0.47 1.55 0.73 5.00
131 INT208142 Gene_expression of PITX1 3 0.65 9.36 0.73 5.00
132 INT59175 Localization of TNMD 4 0.70 4.14 0.71 5.00
133 INT117392 Binding of Insr 8 0.23 4.88 0.68 5.00
134 INT276227 Gene_expression of UBL4A 9 0.20 7.12 0.64 5.00
135 INT72483 Binding of ANTXR2 15 0.35 16.09 0.63 5.00
136 INT128498 Regulation of CCND1 17 0.39 12.51 0.58 5.00
137 INT4098 Negative_regulation of Antxr1 2 0.17 0.61 0.52 5.00
138 INT242208 Regulation of Gene_expression of SRGN 7 0.29 3.15 0.52 5.00
139 INT221447 Gene_expression of SERINC1 4 0.30 2.73 0.51 5.00
140 INT4597 Regulation of SCD 5 0.39 2.25 0.5 5.00
141 INT189634 Regulation of DCN 3 0.25 1.69 0.49 5.00
142 INT13717 Positive_regulation of TYMS 3 0.40 1.64 0.49 5.00
143 INT9020 Binding of Tsv 2 0.25 1.28 0.48 5.00
144 INT247621 Gene_expression of PAMR1 4 0.06 1.49 0.44 5.00
145 INT243550 Gene_expression of PSPH 7 0.25 7.49 0.4 5.00
146 INT165342 Gene_expression of TGFBI 13 0.59 5.81 0.39 5.00
147 INT165400 Positive_regulation of TST 13 0.68 4.25 0.35 5.00
148 INT56696 Gene_expression of Antxr1 13 0.34 3.04 0.34 5.00
149 INT235306 Gene_expression of IGKC 5 0.38 3.18 0.34 5.00
150 INT297602 Positive_regulation of Tsv 3 0.07 3.36 0.33 5.00
151 INT158485 Gene_expression of Grm6 12 0.71 1.4 0.33 5.00
152 INT301036 Binding of Trpm1 1 0.36 0.55 0.23 5.00
153 INT301039 Positive_regulation of Gene_expression of Trpm1 1 0.46 0.55 0.23 5.00
154 INT265632 Positive_regulation of Tnmd 1 0.21 0.05 0.22 5.00
155 INT273158 Binding of COL8A2 1 0.33 2.02 0.22 5.00
156 INT265633 Localization of Tnmd 3 0.33 0 0.22 5.00
157 INT301028 Regulation of Trpm1 1 0.27 0.76 0.22 5.00
158 INT133858 Negative_regulation of BCS1L 13 0.51 8.65 0.2 5.00
159 INT218762 Localization of ZEB1 2 0.65 0.09 0.2 5.00
160 INT340759 Gene_expression of AZGP1 1 0.54 5.4 0.17 5.00
161 INT251821 Negative_regulation of COL11A1 3 0.42 3.45 0.16 5.00
162 INT261721 Negative_regulation of Stl2 1 0.07 1.38 0.16 5.00
163 INT266213 Positive_regulation of Grm6 2 0.46 1.88 0.16 5.00
164 INT301040 Positive_regulation of NYX 1 0.49 1.11 0.16 5.00
165 INT301029 Localization of Grm6 1 0.16 1.15 0.14 5.00
166 INT340760 Positive_regulation of Gene_expression of AZGP1 1 0.48 1.05 0.13 5.00
167 INT340758 Negative_regulation of Gene_expression of IGKC 1 0.24 1.04 0.13 5.00
168 INT301037 Regulation of Grm6 1 0.06 0.05 0.1 5.00
169 INT289450 Regulation of Gene_expression of PITX1 1 0.04 0.71 0.09 5.00
170 INT321381 Localization of Arih2 1 0.08 1.63 0.08 5.00
171 INT145375 Transcription of CCND1 7 0.52 3.86 0.07 5.00
172 INT213826 Binding of Vwa1 1 0.01 1.08 0.07 5.00
173 INT273145 Negative_regulation of COL8A2 1 0.40 0.83 0.06 5.00
174 INT273155 Gene_expression of COL8A2 1 0.53 0.74 0.05 5.00
175 INT253217 Gene_expression of Mapk1ip1 1 0.58 0.25 0.05 5.00
176 INT253220 Regulation of Gene_expression of Mapk1ip1 1 0.39 0.25 0.05 5.00
177 INT253221 Positive_regulation of Gene_expression of Mapk1ip1 1 0.43 0.25 0.05 5.00
178 INT227780 Gene_expression of GON4L 2 0.13 2.72 0.05 5.00
179 INT329016 Regulation of Gene_expression of GON4L 1 0.06 1.12 0.05 5.00
180 INT329020 Regulation of GON4L 1 0.06 1.12 0.05 5.00
181 INT177342 Negative_regulation of SRGN 15 0.28 5.66 0.04 5.00
182 INT329018 Binding of SRGN 1 0.23 1.21 0.03 5.00
183 INT329019 Negative_regulation of Binding of SRGN 1 0.28 1.22 0.03 5.00
184 INT289451 Binding of RXFP1 1 0.09 0.18 0 5.00
185 INT289453 Positive_regulation of Positive_regulation of RXFP1 1 0.10 0.08 0 5.00
186 INT273154 Positive_regulation of Localization of SCD 1 0.03 0.94 0 5.00
187 INT289454 Gene_expression of ATL1 1 0.14 0.1 0 5.00
188 INT273142 Gene_expression of Smc3 1 0.09 0.35 0 5.00
189 INT301027 Transcription of Olfr624 1 0.01 0 0 5.00
190 INT289446 Transcription of CALCRL 1 0.01 0.1 0 5.00
191 INT273144 Binding of CHED1 1 0.19 1.7 0 5.00
192 INT329017 Binding of GON4L 1 0.04 0.43 0 5.00
193 INT273157 Localization of COL8A2 1 0.26 0.09 0 5.00
194 INT273150 Regulation of CHED1 1 0.24 0.09 0 5.00
195 INT273143 Negative_regulation of Tat 1 0.01 2.3 0 5.00
196 INT232980 Binding of KRT3 2 0.29 0.43 0 5.00
197 INT289460 Transcription of P2RX2 1 0.06 0.1 0 5.00
198 INT253219 Binding of Mapk1ip1 1 0.32 0.28 0 5.00
199 INT289448 Transcription of TGM1 1 0.19 0.1 0 5.00
200 INT273148 Localization of LCAT 1 0.38 0.91 0 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox