D:Atherosclerotic Plaque

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Disease Term
Synonyms Arterial Fatty Streak, ARTERIAL FATTY STREAKS, Atheroma, ATHEROMAS, Atheromatous Plaques, ATHEROSCLEROTIC PLAQUES, Fatty Streak Arterial, FATTY STREAKS ARTERIAL, Fibroatheroma, Fibroatheromas, Fibroatheromatous Plaque
Documents 869
Hot Single Events 200
Hot Interactions 61

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Atherosclerotic Plaque. They are ordered first by their relevance to Atherosclerotic Plaque and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68 100.00
2 INT334394 ADIPOQ Negative_regulation of Gene_expression of Tnf 1 0.37 1.06 0.18 99.92
3 INT130085 Crp Positive_regulation of Gene_expression of Vcam1 1 0.23 4.34 2.84 99.60
4 INT186185 Binding of SCARB1 and SCARB2 1 0.22 0.58 0.05 99.52
5 INT186192 Binding of SCARB2 and TBP 1 0.02 0.58 0.05 99.52
6 INT114809 Selp Positive_regulation of Gene_expression of F3 1 0.00 0.88 0.34 99.52
7 INT334390 ADIPOQ Positive_regulation of Localization of INS 1 0.09 1.3 0.23 99.52
8 INT186187 LDLR Regulation of Gene_expression of SCARB1 1 0.17 1.71 0.04 99.40
9 INT319753 Mpo Positive_regulation of Timp1 1 0.14 2.13 0.29 99.28
10 INT271345 Negative_regulation of PIGF Negative_regulation of FLT1 1 0.02 1.17 0.13 99.28
11 INT342457 CSF1 Negative_regulation of Gene_expression of CCR4 1 0.00 0.93 0.31 98.96
12 INT156238 Binding of F2rl1 and Tnfsf14 1 0.08 2.85 1.08 98.94
13 INT302379 Crp Positive_regulation of Gene_expression of Ccl2 1 0.10 4.58 0.84 98.84
14 INT162240 Binding of COL7A1 and MMP1 1 0.03 0.86 0.73 98.56
15 INT235544 Binding of Ighm and Olr1 1 0.00 0.68 0.03 98.44
16 INT162239 Binding of COL7A1 and MMP8 1 0.04 0.86 0.73 98.28
17 INT271350 MPO Positive_regulation of TIMP1 1 0.05 1.66 0.29 98.08
18 INT162241 Binding of COL7A1 and MMP13 2 0.03 0.86 0.73 97.88
19 INT239341 Binding of Abca1 and Hdl1 1 0.04 4.78 0 97.88
20 INT239321 Binding of Abca1 and Apoa1 1 0.11 1.61 0 97.88
21 INT262994 Binding of CRP and HSD11B1 1 0.15 3.02 0.03 96.96
22 INT220188 EC Positive_regulation of CADM1 1 0.00 1.72 0.44 96.76
23 INT120896 Binding of CCL2 and Il6 1 0.08 1.2 0.26 96.04
24 INT141623 OLR1 Positive_regulation of Gene_expression of TF 1 0.01 1.39 0.21 96.00
25 INT141625 Crp Positive_regulation of Gene_expression of TF 1 0.11 1.39 0.21 96.00
26 INT73794 Binding of HSD11B1 and Igfbp1 1 0.06 1.15 0.07 95.24
27 INT186191 Binding of SCARB1 and TBP 1 0.03 2.57 0.24 94.84
28 INT186188 Binding of SCARB1 and PDZK1 1 0.53 0.54 0.05 94.48
29 INT336751 Binding of Selp and Cd40 1 0.03 2.49 0.18 93.96
30 INT294708 CRP Positive_regulation of Gene_expression of VCAM1 2 0.31 1.92 0.56 93.64
31 INT342458 CSF1 Positive_regulation of Gene_expression of CCL2 1 0.17 0.84 0.27 92.40
32 INT271349 ACCS Positive_regulation of PAPPA 1 0.06 0.87 0.09 92.00
33 INT268445 Olr1 Positive_regulation of Positive_regulation of Lipa 1 0.01 0.87 0 91.36
34 INT95644 PROC Negative_regulation of NPEPPS 1 0.00 1.24 0.35 90.28
35 INT182771 ROS1 Positive_regulation of NFKB1 Positive_regulation of CRP 1 0.00 3.83 0.28 89.44
36 INT60213 Binding of Ptgs1 and Ptgs2 2 0.37 0.5 0.97 89.44
37 INT235546 Stat6 Positive_regulation of Positive_regulation of Hand2 1 0.02 0.9 0.14 88.80
38 INT186190 OLR1 Positive_regulation of SCARB1 1 0.01 0.67 0 88.52
39 INT333160 asa Negative_regulation of Gene_expression of Vcam1 1 0.19 0.71 0.5 88.44
40 INT333168 Tlx2 Negative_regulation of Gene_expression of Vcam1 1 0.14 0.71 0.51 88.28
41 INT249968 Cxcr4 Positive_regulation of Cxcl12 1 0.17 0.55 0.08 87.84
42 INT186183 Binding of SCARB2 and SASH3 1 0.00 0.49 0.04 87.80
43 INT230750 Crp Positive_regulation of Edn1 1 0.10 0.27 0.09 87.80
44 INT230746 Crp Positive_regulation of Localization of Serpine1 1 0.16 0.27 0.09 87.80
45 INT123462 Binding of TNF and Tnfrsf11b 3 0.21 3.52 0.24 87.52
46 INT186186 LDLR Regulation of SCARB1 1 0.08 0.65 0.03 86.88
47 INT333156 Tlx2 Regulation of Gene_expression of Icam1 1 0.06 0.59 0.48 85.04
48 INT333151 asa Regulation of Gene_expression of Icam1 1 0.09 0.59 0.48 84.52
49 INT271344 MPO Regulation of Protein_catabolism of ACCS 1 0.02 2.42 0.51 84.36
50 INT182773 ROS1 Positive_regulation of NFKB1 Positive_regulation of IL6 1 0.00 1.9 0.14 84.32
51 INT182782 NFKB1 Positive_regulation of IL6 1 0.00 1.8 0.14 84.32
52 INT182772 ROS1 Positive_regulation of NFKB1 Positive_regulation of IL1B 1 0.00 1.89 0.14 83.84
53 INT182780 NFKB1 Positive_regulation of IL1B 1 0.00 1.8 0.14 83.84
54 INT247439 Binding of APOA1 and HSD11B1 3 0.32 5.01 0.03 83.08
55 INT300197 Binding of APOA1 and C1S 1 0.39 3.56 0 82.92
56 INT239237 TCN2 Positive_regulation of Gene_expression of Serpine1 1 0.00 0.68 0.08 82.52
57 INT242883 INS Negative_regulation of Gene_expression of TLR2 1 0.17 2.35 0.6 82.12
58 INT242875 INS Negative_regulation of Gene_expression of TLR4 1 0.11 1.41 0.24 82.12
59 INT123660 F2R Positive_regulation of PAR1 2 0.10 1.96 0.22 82.04
60 INT123664 F2R Positive_regulation of PAR4 1 0.03 0.51 0.19 82.04
61 INT277063 CRP Positive_regulation of Gene_expression of MMP10 1 0.39 1.53 0.48 81.28
62 INT333161 asa Negative_regulation of Positive_regulation of Vcam1 1 0.22 0.57 0.47 79.64
63 INT329589 Serpina5 Positive_regulation of PTX3 1 0.03 1.52 0.66 79.20
64 INT277064 CRP Positive_regulation of Gene_expression of TIMP1 1 0.15 1.47 0.45 79.12
65 INT345157 Lpar1 Positive_regulation of Gene_expression of Gtf3a 1 0.00 0.89 0.15 78.44
66 INT90387 ROS1 Positive_regulation of NFKB1 4 0.32 2.35 0.87 78.16
67 INT277065 CRP Positive_regulation of Gene_expression of MMP1 1 0.41 1.52 0.47 78.08
68 INT239328 Hdl1 Regulation of Gene_expression of Kitl 1 0.08 1.86 0.2 78.08
69 INT266659 Binding of MMP9 and MOCS1 1 0.01 1.71 0.94 78.04
70 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 77.36
71 INT132115 Binding of Crp and Nfkb1 1 0.06 1.04 0.3 77.04
72 INT213010 Hdl1 Negative_regulation of Gene_expression of Icam1 1 0.15 1.01 0.15 76.92
73 INT277011 CRP Positive_regulation of Gene_expression of F3 1 0.06 1.03 0.32 76.00
74 INT277066 MMP1 Positive_regulation of Gene_expression of TIMP1 1 0.16 0.76 0.24 75.28
75 INT106823 Binding of MBP and PAPPA 2 0.17 3.89 0.05 75.12
76 INT273892 LPA Positive_regulation of ALB 1 0.01 0.95 0.1 75.12
77 INT186189 LDLR Positive_regulation of Gene_expression of SCARB1 1 0.14 1.27 0 74.16
78 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12 72.20
79 INT191503 CD40LG Regulation of Gene_expression of F3 1 0.01 0.99 0.27 71.76
80 INT344723 Niacr1 Positive_regulation of Binding of APOB 1 0.31 1.05 0 71.60
81 INT228175 RNU1-1 Regulation of Adipoq 1 0.11 0.78 0.12 70.72
82 INT344396 Ucp2 Regulation of Ros1 1 0.04 1.31 0.31 70.08
83 INT239337 Abca1 Positive_regulation of RCT 1 0.07 3.11 0.24 69.32
84 INT216880 Apoc4 Positive_regulation of Hmox1 1 0.03 1.06 0.25 69.20
85 INT224026 P2RY6 Positive_regulation of NRP2 1 0.10 0.98 0.1 69.08
86 INT239333 Abcg1 Positive_regulation of RCT 1 0.06 1.29 0.03 68.92
87 INT276496 Binding of TF and F7 1 0.18 0.81 0.08 68.64
88 INT349105 Hyal1 Positive_regulation of Gene_expression of Il6 1 0.30 0.25 0 68.32
89 INT123662 Negative_regulation of F2R Positive_regulation of MAPK14 1 0.08 0.42 0.26 67.72
90 INT344720 Niacr1 Negative_regulation of Binding of Hdl1 1 0.17 1.13 0 67.44
91 INT123663 F2R Positive_regulation of MAPK14 1 0.12 0.42 0.26 67.32
92 INT123661 COL7A1 Positive_regulation of MAPK14 1 0.08 0.42 0.26 67.32
93 INT323279 Binding of Nos3 and Arg2 1 0.01 0.67 0 67.28
94 INT239322 Hdl1 Positive_regulation of RCT 1 0.02 2.16 0.03 66.96
95 INT271343 Binding of CRP and PAPPA 1 0.20 0.86 0.1 66.88
96 INT239340 Cand1 Positive_regulation of RCT 1 0.11 1.26 0.03 66.80
97 INT213041 Hdl1 Negative_regulation of Gene_expression of Vcam1 1 0.14 0.9 0.17 66.48
98 INT265956 Clas4 Regulation of PPARA 1 0.01 0.7 0.14 66.16
99 INT213026 Hdl1 Positive_regulation of Nos3 5 0.16 7.92 0.73 65.88
100 INT175909 Binding of ROS1 and CNBP 1 0.01 1.78 0.19 65.64
101 INT175908 Binding of NOS3 and ROS1 1 0.10 1.84 0.19 65.64
102 INT290029 Binding of INS and NR1H4 1 0.01 0.47 0 65.04
103 INT290031 Binding of INS and PPARG 1 0.11 0.47 0 65.04
104 INT290025 Binding of INS and PPARD 1 0.03 0.47 0 65.04
105 INT290032 Binding of INS and RXRG 1 0.03 0.47 0 65.04
106 INT302381 Il33 Regulation of Gene_expression of Il4 1 0.01 0.76 0.16 64.48
107 INT156234 Tnfsf14 Positive_regulation of Transcription of F2rl1 1 0.09 1.26 0.42 64.40
108 INT156239 Tnfsf14 Positive_regulation of F2rl1 1 0.09 2.4 0.81 63.44
109 INT182783 INS Positive_regulation of Gene_expression of ETV3 1 0.01 1.89 0 63.20
110 INT239783 Kcnip4 Positive_regulation of Gene_expression of Prh1 1 0.03 0.6 0.29 62.84
111 INT182784 IGF1 Positive_regulation of Gene_expression of INS 1 0.02 1.87 0 62.84
112 INT182778 IGF1 Positive_regulation of Gene_expression of ETV3 1 0.03 1.89 0 62.84
113 INT182777 IAPP Positive_regulation of Gene_expression of ETV3 1 0.06 1.88 0 62.40
114 INT182776 IAPP Positive_regulation of Gene_expression of INS 1 0.03 1.87 0 62.40
115 INT242035 Binding of SNRNP70 and CHDH 1 0.02 3.41 0.06 61.52
116 INT290026 Binding of PPARG and CHDH 1 0.10 6.61 0 61.52
117 INT179160 IL6 Regulation of Gene_expression of IL13 1 0.03 0.12 0.11 60.16
118 INT179159 IL8 Regulation of Gene_expression of IL6 1 0.02 0.12 0.11 60.16
119 INT179165 IL8 Regulation of Gene_expression of IL13 1 0.02 0.12 0.11 60.16
120 INT136749 COX5A Positive_regulation of Gene_expression of SCARB1 1 0.52 0.36 0.45 59.88
121 INT341308 Negative_regulation of Npc1 Positive_regulation of Gene_expression of Srebf1 1 0.31 1.48 0 59.28
122 INT277016 Binding of MB and PAPPA 1 0.10 1 0.07 59.28
123 INT213027 Binding of Apoa1 and Scarb1 6 0.09 7.52 0.43 58.96
124 INT290033 Binding of PPARD and NR1H4 1 0.01 0.39 0 58.96
125 INT290027 Binding of PPARG and NR1H4 1 0.03 0.39 0 58.96
126 INT290024 Binding of PPARG and RXRG 1 0.15 0.39 0 58.56
127 INT290023 Binding of PPARD and RXRG 1 0.03 0.39 0 58.56
128 INT345303 MMP15 Positive_regulation of MMP13 1 0.00 1.18 0.58 57.84
129 INT277010 Binding of PAPPA and TNNT1 1 0.24 0.99 0.07 57.52
130 INT138260 Csi Regulation of IFNA1 1 0.00 0.06 0 57.48
131 INT138261 Csi Regulation of TNF 1 0.01 0.06 0 57.48
132 INT138262 Csi Regulation of IL6 1 0.00 0.06 0 57.48
133 INT302384 IL6 Positive_regulation of Localization of Crp 1 0.10 1.39 0.15 57.28
134 INT345302 MMP15 Positive_regulation of MMP2 1 0.06 1.17 0.57 56.72
135 INT290030 Binding of PPARD and PPARG 1 0.09 0.38 0 56.24
136 INT277072 Binding of PLA2G7 and Lipg 1 0.00 1.32 0.21 55.88
137 INT262996 ADIPOQ Regulation of INS 1 0.13 1.25 0.1 55.68
138 INT239339 Hdl1 Negative_regulation of Gene_expression of Paf 1 0.02 1.43 0.13 55.68
139 INT216881 Binding of Apoc4 and Hmox1 1 0.01 1.78 0.4 55.44
140 INT207356 PTGER2 Regulation of Gene_expression of CYP27A1 1 0.00 0.05 0.03 54.24
141 INT207361 PTGDS Regulation of Gene_expression of CYP27A1 1 0.01 0.05 0.03 54.24
142 INT156233 Positive_regulation of Tnfsf14 Positive_regulation of F2rl1 1 0.09 1.15 0.4 54.00
143 INT242878 INS Negative_regulation of Gene_expression of SPI1 1 0.04 1.81 0.27 53.96
144 INT239316 Nr1h2 Positive_regulation of Transcription of Abca1 1 0.15 0.67 0.18 52.88
145 INT239346 Olfr642 Positive_regulation of Lcat 1 0.00 1.06 0.07 51.92
146 INT213030 Hdl1 Regulation of Gene_expression of Edn1 1 0.06 0.88 0 49.60
147 INT277012 Binding of PAPPA and ACE2 1 0.02 1.26 0.15 48.72
148 INT249962 Binding of KIT and KITLG 6 0.19 3.69 0.17 48.16
149 INT224410 Binding of CRP and CIMT 3 0.42 10.46 1.2 44.24
150 INT323278 Dhfr Negative_regulation of Negative_regulation of Igkv1-131 1 0.02 0.93 1.02 43.40
151 INT313509 Binding of ALOX5 and SP1 1 0.07 1.51 0.08 43.36
152 INT323280 Dhfr Negative_regulation of Igkv1-131 1 0.02 0.47 0.51 42.16
153 INT213005 Hdl1 Positive_regulation of Akt1 3 0.19 3.81 0.14 41.08
154 INT156237 Binding of F2r and Tnfsf14 1 0.02 1.14 0.4 39.36
155 INT213008 Hdl1 Positive_regulation of Gene_expression of Edn1 1 0.10 0.85 0 38.84
156 INT154173 Binding of SIPA1 and SYK 1 0.16 0.46 0 37.68
157 INT272300 Binding of LPA and PLG 1 0.09 0.66 0 35.72
158 INT272301 Negative_regulation of Binding of LPA and PLG 1 0.08 0.68 0 35.72
159 INT268459 Binding of LDLR and Olr1 1 0.00 0.78 0 33.96
160 INT265934 SREBF1 Positive_regulation of Transcription of SERPINE1 1 0.01 0.62 0 27.88
161 INT239229 Regulation of Binding of Edn1 and Ednra 1 0.01 0.37 0.03 27.68
162 INT239228 Regulation of Binding of Edn1 and Ednrb 1 0.02 0.37 0.03 27.68
163 INT239224 Positive_regulation of Binding of Edn1 and Ednrb 1 0.02 0.37 0.03 27.68
164 INT175910 SERPINE1 Negative_regulation of PLAU 1 0.06 1.01 0.22 27.36
165 INT271354 MPO Regulation of Gene_expression of CRP 1 0.16 1.74 0.08 26.80
166 INT271351 MPO Positive_regulation of CRP 1 0.07 1.69 0.08 26.80
167 INT239352 Binding of C1S and Hdl1 1 0.06 1.73 0 26.80
168 INT239225 Binding of Edn1 and Ednrb 1 0.02 0.36 0.03 26.32
169 INT213042 Apoa1 Positive_regulation of Nos3 1 0.10 2.17 0.11 26.00
170 INT271348 Binding of CHKB and MB 1 0.01 1.01 0 26.00
171 INT239226 Binding of Edn1 and Ednra 2 0.06 1.59 0.26 25.68
172 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4 25.36
173 INT156235 Tnfsf14 Positive_regulation of F2r 1 0.03 1.03 0.35 25.00
174 INT228984 CRP Positive_regulation of IL6 2 0.63 0.99 0.17 25.00
175 INT265826 Binding of ACE and SERPINE1 1 0.24 1.08 0.3 24.72
176 INT271355 PGF Positive_regulation of PIGF 1 0.01 0.99 0.06 24.32
177 INT239349 Hdl1 Negative_regulation of Tbxa2r 1 0.03 3.37 0 23.80
178 INT224040 Mtpn Positive_regulation of P2RY1 1 0.00 0.85 0.12 23.32
179 INT175911 Binding of SERPINE1 and CNBP 1 0.01 1.02 0.22 21.68
180 INT329371 IL8 Negative_regulation of Jun 1 0.00 0.95 0.13 21.36
181 INT353836 Binding of CEACAM7 and ICA1 1 0.08 0.32 0.39 21.28
182 INT329368 Ccl2 Negative_regulation of Jun 1 0.01 1.87 0.24 21.00
183 INT174266 TNF Regulation of Gene_expression of F3 1 0.00 3.2 0.33 20.48
184 INT174265 IL18 Regulation of Gene_expression of F3 1 0.00 3.21 0.33 20.48
185 INT254855 Agt Positive_regulation of Tgfb1 1 0.03 0.18 0.13 20.40
186 INT287494 CRP Positive_regulation of Gene_expression of CCL2 2 0.30 2.33 0.83 19.84
187 INT213043 Regulation of Binding of Apoa1 and Scarb1 1 0.05 1.12 0 18.08
188 INT213049 Hdl1 Regulation of Gene_expression of Nppc 1 0.09 1 0 17.08
189 INT191494 IL6 Positive_regulation of Binding of CRP 1 0.02 1.65 0.65 16.80
190 INT277990 Binding of Cd3e and Hand1 1 0.01 0.5 0.16 16.64
191 INT240619 Binding of CRP and ADIPOQ 8 0.18 10.74 0.78 15.44
192 INT262997 Binding of HSD11B1 and ADIPOQ 1 0.54 2.82 0.07 15.44
193 INT181619 ACE Positive_regulation of KNG1 1 0.33 0.97 0.58 15.36
194 INT268446 Cdk5 Positive_regulation of Cdk5r1 1 0.02 0.58 0 12.40
195 INT182804 Binding of ETV3 and T2DM 1 0.10 2.62 0 12.24
196 INT242301 Binding of EGFR and ACCS 1 0.11 1.31 0 10.56
197 INT333150 Tlx2 Regulation of asa 1 0.04 2.17 1.55 9.24
198 INT254769 Binding of LDLR and Apoe 1 0.03 0 0.28 7.40
199 INT239344 Nr1h2 Positive_regulation of Gene_expression of Srebf1 1 0.26 0.84 0.29 7.16
200 INT239324 Nr1h2 Positive_regulation of Hltf 1 0.04 0.78 0.29 7.16

Single Events

The table below shows the top 200 pain related interactions that have been reported for Atherosclerotic Plaque. They are ordered first by their pain relevance and then by number of times they were reported in Atherosclerotic Plaque. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT136752 Positive_regulation of Gene_expression of SCARB1 5 0.69 10.63 1.76 100.00
2 INT13240 Gene_expression of TF 94 0.76 57.81 10.99 100.00
3 INT67101 Gene_expression of DST 47 0.54 25.92 9.59 100.00
4 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26 100.00
5 INT61171 Gene_expression of S100A8 92 0.76 57.74 9.98 100.00
6 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 100.00
7 INT113420 Positive_regulation of Gene_expression of IL18 22 0.69 19.96 5.53 100.00
8 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 100.00
9 INT94042 Positive_regulation of Gene_expression of S100A8 15 0.67 13.52 2.44 100.00
10 INT18833 Positive_regulation of LTB4R 19 0.69 27.61 10.17 100.00
11 INT222230 Positive_regulation of Gene_expression of Cxcl12 11 0.59 5.26 2.13 100.00
12 INT180031 Gene_expression of IBGC1 1 0.05 1.38 0.2 100.00
13 INT69000 Positive_regulation of Gene_expression of PROC 6 0.20 5.87 1.84 99.98
14 INT88523 Positive_regulation of Negative_regulation of PROC 4 0.01 3.76 1.76 99.98
15 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94 99.98
16 INT96084 Binding of Selp 12 0.48 8.41 2.16 99.92
17 INT20470 Positive_regulation of Acsl1 5 0.40 3.76 1.03 99.88
18 INT94438 Gene_expression of OLR1 86 0.78 80.38 11.03 99.84
19 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95 99.84
20 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72 99.84
21 INT178198 Gene_expression of C3 62 0.78 39.5 7.69 99.84
22 INT80223 Positive_regulation of Hmox1 128 0.68 77.71 17.64 99.84
23 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 99.84
24 INT80228 Positive_regulation of Gene_expression of Hmox1 68 0.70 62.88 14.01 99.84
25 INT207444 Gene_expression of PLA2G7 8 0.71 11.31 3.18 99.84
26 INT140193 Gene_expression of Mmp3 58 0.71 49.65 25.4 99.84
27 INT158990 Localization of PAPPA 3 0.78 2.48 0.27 99.84
28 INT49994 Gene_expression of Lta 9 0.64 6.94 2.98 99.84
29 INT1755 Gene_expression of GBE1 28 0.26 8.32 5.18 99.84
30 INT222233 Gene_expression of Cxcl12 42 0.69 32.64 10.13 99.84
31 INT67424 Positive_regulation of Gene_expression of Selp 36 0.68 17.08 7.95 99.84
32 INT50673 Positive_regulation of Gene_expression of CPOX 156 0.54 97.31 37.03 99.84
33 INT11030 Binding of LPA 70 0.48 40.35 4.81 99.84
34 INT271368 Negative_regulation of Localization of PAPPA 1 0.41 0.65 0.06 99.84
35 INT136753 Regulation of Gene_expression of SCARB1 2 0.60 7.79 0.77 99.80
36 INT180032 Positive_regulation of CFM1 1 0.02 1.07 0.1 99.76
37 INT130421 Positive_regulation of MSR1 3 0.67 0.57 0.03 99.76
38 INT6365 Localization of Edn1 56 0.81 18.84 13.83 99.76
39 INT28145 Binding of PAPPA 26 0.48 7.4 4.96 99.76
40 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01 99.74
41 INT49487 Gene_expression of Sele 65 0.76 68.11 19.41 99.74
42 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 99.74
43 INT9647 Gene_expression of PROC 163 0.65 89.76 26.75 99.74
44 INT16461 Negative_regulation of Gene_expression of PROC 13 0.24 4.39 2.17 99.74
45 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.72
46 INT118305 Negative_regulation of Gene_expression of IL18 7 0.39 6.52 2.05 99.72
47 INT28642 Gene_expression of CXCR2 60 0.78 38.69 18.11 99.70
48 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 99.68
49 INT65889 Gene_expression of RETNLB 73 0.34 60.98 38.3 99.68
50 INT15033 Gene_expression of Apoe 18 0.78 14.97 3.75 99.68
51 INT207848 Localization of Olr1 3 0.17 2.71 0.43 99.68
52 INT213277 Positive_regulation of Gene_expression of ADIPOQ 14 0.50 17.7 1.14 99.66
53 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 99.64
54 INT79061 Positive_regulation of NOS2 92 0.65 58.89 23.96 99.62
55 INT74449 Positive_regulation of B4GALNT1 53 0.30 34.49 14.96 99.62
56 INT94427 Positive_regulation of Positive_regulation of NOS2 14 0.47 11.15 4.3 99.62
57 INT95369 Positive_regulation of Gene_expression of NOS2 36 0.55 25.09 11.37 99.62
58 INT104075 Positive_regulation of Gene_expression of B4GALNT1 8 0.09 7.36 2.21 99.62
59 INT101010 Positive_regulation of Positive_regulation of B4GALNT1 5 0.06 4.49 1.83 99.62
60 INT136754 Gene_expression of SCARB1 64 0.77 43.28 4.82 99.60
61 INT44954 Gene_expression of APP 191 0.78 105.86 23.9 99.60
62 INT16772 Gene_expression of MPO 81 0.78 90.98 11.9 99.60
63 INT186195 Transcription of SCARB1 1 0.70 1.42 0 99.60
64 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57 99.60
65 INT86521 Gene_expression of Lpar1 167 0.78 154.61 80.35 99.60
66 INT190781 Binding of Acsl1 6 0.36 9.12 0.76 99.60
67 INT145312 Localization of CHI3L1 8 0.78 12.71 1.26 99.60
68 INT153814 Localization of LPA 19 0.65 18.25 7.68 99.60
69 INT125884 Positive_regulation of CHI3L1 15 0.62 34.04 4.43 99.60
70 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31 99.56
71 INT79993 Positive_regulation of Positive_regulation of ACE 2 0.49 0.78 0.1 99.56
72 INT85966 Gene_expression of Cd40lg 50 0.73 30.9 9.11 99.52
73 INT186202 Binding of SCARB2 1 0.19 0.58 0.05 99.52
74 INT812 Localization of INS 1026 0.81 515.6 145.31 99.52
75 INT16722 Negative_regulation of MPO 25 0.59 18.55 6.99 99.50
76 INT73670 Gene_expression of Vcam1 128 0.78 123.79 24.96 99.48
77 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 99.48
78 INT61257 Gene_expression of Sele 79 0.77 70.97 17.78 99.48
79 INT88820 Positive_regulation of Gene_expression of F3 8 0.67 5.48 1.08 99.48
80 INT262999 Negative_regulation of Gene_expression of ADIPOQ 7 0.43 9.52 0.12 99.48
81 INT268438 Negative_regulation of Binding of Lipa 1 0.14 0.49 0 99.48
82 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2 99.42
83 INT2673 Negative_regulation of PROC 93 0.57 50.34 12.79 99.42
84 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 99.36
85 INT207852 Positive_regulation of Olr1 9 0.12 9.76 2.26 99.36
86 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 99.34
87 INT70050 Negative_regulation of IL10 56 0.58 37.45 12.39 99.34
88 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 99.34
89 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 99.34
90 INT47939 Gene_expression of Selp 171 0.76 87.54 39.03 99.32
91 INT46088 Localization of F3 15 0.37 13.7 2.23 99.32
92 INT44003 Gene_expression of F3 40 0.75 27.92 8.29 99.30
93 INT122041 Binding of Ppara 308 0.48 189.17 51.48 99.30
94 INT59870 Gene_expression of F3 51 0.65 51.83 14.01 99.24
95 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.24
96 INT49473 Gene_expression of MSR1 14 0.75 7.28 2.64 99.20
97 INT186197 Gene_expression of SCARB2 7 0.40 2.93 0.13 99.20
98 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 99.20
99 INT173587 Protein_catabolism of COL5A2 59 0.32 32.73 8.96 99.16
100 INT136755 Negative_regulation of Gene_expression of SCARB1 2 0.57 6.61 0.63 99.14
101 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.14
102 INT75869 Gene_expression of Acsl1 24 0.45 27.76 3.66 99.14
103 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98 99.12
104 INT123779 Positive_regulation of MMP13 42 0.65 24.3 12.45 99.12
105 INT82871 Protein_catabolism of MMP1 13 0.96 10.71 4.09 99.08
106 INT195414 Gene_expression of ALOX5AP 65 0.72 31.22 15.25 99.08
107 INT232538 Gene_expression of FAM5C 1 0.77 12.35 0.25 99.04
108 INT136757 Regulation of SCARB1 4 0.27 1.96 0.48 98.96
109 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 98.96
110 INT94285 Negative_regulation of CD36 10 0.43 6.61 1.98 98.96
111 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66 98.96
112 INT182233 Gene_expression of CCR4 14 0.43 6.55 3.31 98.96
113 INT24907 Gene_expression of PAPPA 42 0.75 28.32 6.63 98.94
114 INT79062 Gene_expression of B4GALNT1 42 0.14 18.89 6.98 98.94
115 INT111018 Binding of F2rl1 5 0.30 3.11 2.02 98.94
116 INT156229 Binding of Tnfsf14 5 0.23 4.69 1.6 98.94
117 INT114901 Binding of TBP 6 0.17 2.45 0.11 98.92
118 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 98.88
119 INT117614 Positive_regulation of PAPPA 18 0.67 11.9 3.76 98.88
120 INT224413 Positive_regulation of CIMT 25 0.68 23.61 3.14 98.88
121 INT58765 Positive_regulation of Gene_expression of ANGPT2 11 0.38 8.2 0.81 98.88
122 INT107381 Positive_regulation of Gene_expression of PAPPA 4 0.49 2.32 0.85 98.88
123 INT64170 Gene_expression of GLI2 31 0.46 14.96 3.99 98.84
124 INT182322 Negative_regulation of Gene_expression of GLI2 6 0.11 2.37 0.98 98.84
125 INT17021 Negative_regulation of AHSP 5 0.43 3.45 0.72 98.80
126 INT39406 Positive_regulation of OLR1 45 0.70 37.8 7.72 98.78
127 INT78182 Positive_regulation of ACCS 43 0.43 46.39 6.78 98.76
128 INT94454 Gene_expression of CD68 73 0.72 63.94 10.43 98.76
129 INT79060 Gene_expression of NOS2 116 0.78 69.25 34.84 98.74
130 INT187189 Positive_regulation of Gene_expression of BSG 1 0.61 6.21 5.02 98.72
131 INT180033 Regulation of CFM1 2 0.21 1.09 0.1 98.68
132 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02 98.68
133 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42 98.64
134 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 98.64
135 INT74587 Gene_expression of MMP8 31 0.78 24.4 14.91 98.64
136 INT95631 Positive_regulation of Gene_expression of MMP8 16 0.50 13.75 5.12 98.64
137 INT173208 Binding of CNBP 9 0.25 11.01 1.23 98.62
138 INT239302 Positive_regulation of Gene_expression of Abca1 9 0.32 9.1 1.06 98.60
139 INT190081 Gene_expression of Abca1 21 0.65 18.18 2.45 98.60
140 INT1087 Negative_regulation of Msr1 32 0.57 8.35 10.72 98.60
141 INT110110 Gene_expression of ACCS 85 0.58 75.88 10.2 98.56
142 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86 98.56
143 INT87863 Positive_regulation of IL18 40 0.69 34.08 9.53 98.52
144 INT27268 Localization of Gtf3a 71 0.21 56.93 12.51 98.52
145 INT139562 Transcription of IL18 10 0.68 6.14 2.73 98.52
146 INT170546 Gene_expression of Renbp 15 0.32 14.33 0.72 98.48
147 INT133549 Gene_expression of Il15 42 0.69 27.84 14.74 98.48
148 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 98.48
149 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 98.44
150 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 98.44
151 INT81444 Positive_regulation of Gene_expression of Vcam1 40 0.70 46.38 8.58 98.44
152 INT20207 Binding of Ighm 14 0.46 2.88 1.79 98.44
153 INT170333 Binding of IFN1@ 68 0.47 49.01 9.72 98.40
154 INT129962 Positive_regulation of Gene_expression of MMP13 41 0.65 20.74 8.54 98.36
155 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05 98.36
156 INT95632 Positive_regulation of MMP8 26 0.70 10.06 9.96 98.36
157 INT99610 Localization of MMP9 126 0.79 48.46 32.67 98.32
158 INT187190 Positive_regulation of Localization of MMP9 27 0.68 8.1 8.93 98.32
159 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 98.28
160 INT58766 Gene_expression of ANGPT2 41 0.67 21.65 4.82 98.26
161 INT139803 Gene_expression of PTX3 22 0.75 26.21 5.07 98.24
162 INT6481 Binding of TNF 624 0.48 510.2 214.82 98.24
163 INT268442 Binding of Lipa 1 0.12 0.48 0 98.24
164 INT306910 Negative_regulation of Gene_expression of Ephx2 4 0.55 3.8 0.67 98.20
165 INT161105 Gene_expression of Ephx2 20 0.78 17.84 3.58 98.20
166 INT182785 Gene_expression of NHEJ1 1 0.01 1.08 0.06 98.20
167 INT142802 Binding of Ldlr 8 0.47 5.08 0.65 98.16
168 INT131654 Positive_regulation of Gene_expression of Olr1 3 0.36 2.38 0.81 98.16
169 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 98.12
170 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9 98.08
171 INT16290 Gene_expression of BSG 60 0.68 38.73 32.86 98.08
172 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71 98.08
173 INT92823 Positive_regulation of Gene_expression of MMP1 65 0.68 25.69 14.31 98.04
174 INT49103 Positive_regulation of Vcam1 71 0.69 59.52 19.85 98.00
175 INT271369 Negative_regulation of PIGF 1 0.12 1.11 0.13 98.00
176 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01 97.96
177 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94 97.96
178 INT71174 Gene_expression of CASP1 44 0.75 30.3 9.37 97.96
179 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 97.96
180 INT49653 Gene_expression of NFKB2 12 0.61 9.51 2.73 97.96
181 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 97.96
182 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 97.96
183 INT121496 Gene_expression of TERT 107 0.78 45.6 7.42 97.96
184 INT121493 Gene_expression of XRCC1 55 0.65 73.43 2.76 97.96
185 INT84060 Regulation of Apoe 4 0.62 3.33 2.05 97.96
186 INT65684 Gene_expression of MDM2 30 0.62 24.94 1.55 97.96
187 INT136751 Negative_regulation of SCARB1 6 0.43 2.65 0.7 97.92
188 INT169697 Negative_regulation of Ephx2 35 0.59 38.21 5.92 97.92
189 INT76915 Localization of Gpx3 6 0.14 4.48 0.89 97.92
190 INT110427 Gene_expression of Spp1 199 0.78 176.11 23.31 97.88
191 INT122902 Positive_regulation of Gene_expression of Spp1 54 0.70 56.3 6.33 97.88
192 INT180379 Gene_expression of Olr1 31 0.36 36.46 4.84 97.84
193 INT83190 Gene_expression of Olr1 26 0.59 12.47 2.91 97.84
194 INT175914 Positive_regulation of Iph1 1 0.01 3.18 0.82 97.84
195 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41 97.84
196 INT175915 Negative_regulation of Positive_regulation of Iph1 1 0.01 1.67 0.42 97.84
197 INT93663 Positive_regulation of MMP1 72 0.67 33.38 19.86 97.80
198 INT9650 Gene_expression of LPA 141 0.75 104.57 29 97.80
199 INT9648 Positive_regulation of Gene_expression of LPA 15 0.59 11.31 1.72 97.80
200 INT17996 Binding of Crp 40 0.37 31.4 7.8 97.80
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