D:Athletic Injuries

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Disease Term
Synonyms Athletic Injury, Injuries Athletic, Injuries Sports, Injury Athletic, Injury Sports, Sports Injuries, Sports Injury
Documents 333
Hot Single Events 8
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Athletic Injuries. They are ordered first by their relevance to Athletic Injuries and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT185358 Binding of MCS and PCS 7 0.22 3.34 0.57 75.24
2 INT178663 Binding of CXCR3 and TH1L 2 0.04 2.24 1.01 5.00
3 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86 5.00
4 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 5.00
5 INT178664 Binding of CCR5 and TH1L 1 0.04 1.04 0.44 5.00
6 INT355018 Binding of FAS and Faslg 1 0.12 1.34 0.37 5.00
7 INT178662 IFN1@ Positive_regulation of CXCL9 1 0.20 0.5 0.36 5.00
8 INT290614 Binding of Th and RLS 1 0.21 3.26 0.31 5.00
9 INT355023 Phosphorylation of Rtn4r Negative_regulation of Binding of Mag and Rtn4r 1 0.00 0.38 0.11 5.00
10 INT355008 Binding of Mag and Rtn4r 1 0.02 0.36 0.1 5.00
11 INT355019 Lif Positive_regulation of JAK1 1 0.00 0.69 0.08 5.00
12 INT355021 Cntf Positive_regulation of SOAT1 1 0.02 0.7 0.08 5.00
13 INT355022 Cntf Positive_regulation of JAK1 1 0.00 0.69 0.08 5.00
14 INT355009 Cntf Positive_regulation of Il6st 1 0.02 0.69 0.08 5.00
15 INT355020 Lif Positive_regulation of SOAT1 1 0.02 0.7 0.08 5.00
16 INT355010 Lif Positive_regulation of Il6st 1 0.02 0.69 0.08 5.00
17 INT238270 Binding of VMO1 and MSLNL 1 0.11 0.42 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Athletic Injuries. They are ordered first by their pain relevance and then by number of times they were reported in Athletic Injuries. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT72370 Gene_expression of Timp1 82 0.65 57.52 24.16 94.20
2 INT175904 Localization of RAC1 7 0.41 5.05 0.86 92.68
3 INT267800 Regulation of Gene_expression of RLS 2 0.29 3.79 1.07 85.64
4 INT54924 Gene_expression of RLS 67 0.62 83.2 14.25 85.16
5 INT267808 Positive_regulation of Gene_expression of RLS 4 0.41 5.96 0.94 84.48
6 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24 84.44
7 INT9088 Negative_regulation of LBP 48 0.58 33.06 25.89 81.04
8 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 80.84
9 INT214860 Binding of GYPC 10 0.36 11.18 0.74 79.04
10 INT35143 Negative_regulation of ANGPTL5 28 0.54 18.59 3.14 76.52
11 INT88868 Binding of MCS 45 0.40 37.43 7.98 75.24
12 INT134346 Binding of PCS 51 0.37 22.27 5.67 75.24
13 INT608 Negative_regulation of KNG1 98 0.43 72.36 31.23 74.80
14 INT65207 Positive_regulation of Positive_regulation of Fgf2 10 0.70 3.5 2.08 73.68
15 INT9832 Gene_expression of Shbg 96 0.75 56.71 12.19 73.48
16 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23 72.80
17 INT61548 Positive_regulation of Fgf2 72 0.70 32.18 14.49 72.80
18 INT67318 Positive_regulation of Hgf 13 0.69 5.47 2.6 72.80
19 INT14 Regulation of LDHA 22 0.57 15.26 2.14 65.28
20 INT101653 Negative_regulation of SAA1 7 0.39 7 1.33 62.72
21 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 60.56
22 INT234 Binding of Alb 151 0.48 52.34 32.97 58.64
23 INT20712 Regulation of gp 8 0.36 1.06 1.67 48.68
24 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83 45.16
25 INT81750 Regulation of Ntrk1 13 0.52 6.03 4.37 45.16
26 INT30238 Positive_regulation of Anpep 14 0.66 2.77 3.38 45.16
27 INT51570 Regulation of Anpep 6 0.43 1.7 2 45.16
28 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 40.64
29 INT82737 Regulation of Hmox2 7 0.14 4.6 2.44 36.96
30 INT9664 Binding of LBP 127 0.48 94.9 63.42 36.88
31 INT107129 Positive_regulation of RLS 46 0.60 40.1 8.09 34.24
32 INT248748 Localization of Pip 2 0.49 1.35 0.16 33.40
33 INT77670 Positive_regulation of ACLY 24 0.49 21.68 3.12 27.08
34 INT195442 Gene_expression of FIG4 23 0.65 5.13 6.92 25.52
35 INT9456 Gene_expression of Anpep 9 0.78 1.69 4.26 25.44
36 INT108384 Binding of Ntrk1 28 0.39 10.73 9.09 24.32
37 INT200443 Positive_regulation of AES 27 0.60 22.46 3.22 20.48
38 INT330743 Negative_regulation of RRIS 1 0.47 2.29 0 14.32
39 INT188844 Gene_expression of AES 44 0.58 33.94 5.85 6.12
40 INT192951 Negative_regulation of AES 15 0.38 6.38 3.5 6.12
41 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 5.00
42 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 5.00
43 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 5.00
44 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 5.00
45 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 5.00
46 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 5.00
47 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 5.00
48 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
49 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
50 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
51 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 5.00
52 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61 5.00
53 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
54 INT5842 Gene_expression of Gfap 372 0.78 153.71 127.71 5.00
55 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38 5.00
56 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 5.00
57 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 5.00
58 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 5.00
59 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 5.00
60 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 5.00
61 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12 5.00
62 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 5.00
63 INT12001 Regulation of Ngf 97 0.62 54.64 76.25 5.00
64 INT3034 Localization of Ngf 126 0.81 50.81 72.84 5.00
65 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 5.00
66 INT5843 Positive_regulation of Gfap 184 0.70 108.2 70.21 5.00
67 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 5.00
68 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 5.00
69 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28 5.00
70 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
71 INT90911 Positive_regulation of Phosphorylation of Grin1 62 0.70 27.45 59.26 5.00
72 INT6436 Positive_regulation of Positive_regulation of Fos 101 0.70 18.71 57.96 5.00
73 INT7340 Regulation of Grin1 87 0.62 30.37 57.93 5.00
74 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82 5.00
75 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 5.00
76 INT9210 Regulation of IL6 166 0.62 125.61 49.95 5.00
77 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31 5.00
78 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 5.00
79 INT2774 Binding of Crp 241 0.48 195.89 44.39 5.00
80 INT52531 Gene_expression of Nfkb1 153 0.75 82.84 42.9 5.00
81 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 5.00
82 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52 5.00
83 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 5.00
84 INT30817 Gene_expression of Th 142 0.76 33.56 38.12 5.00
85 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
86 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 5.00
87 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 5.00
88 INT19759 Gene_expression of LBP 77 0.77 56.44 33.23 5.00
89 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68 5.00
90 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 5.00
91 INT129207 Gene_expression of Cxcl1 114 0.75 68.54 30.82 5.00
92 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 5.00
93 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
94 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25 5.00
95 INT66025 Gene_expression of Itgam 61 0.78 31.26 26.08 5.00
96 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 5.00
97 INT94335 Positive_regulation of CXCL10 71 0.58 50.69 23 5.00
98 INT74423 Localization of IL10 91 0.80 61.6 22.95 5.00
99 INT71875 Localization of Nfkb1 92 0.78 48.13 22.94 5.00
100 INT6868 Gene_expression of GFAP 136 0.78 84.65 22.7 5.00
101 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73 5.00
102 INT5586 Binding of Fos 47 0.48 12.7 21.33 5.00
103 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
104 INT48663 Negative_regulation of Gene_expression of Gfap 45 0.59 18.34 19.84 5.00
105 INT157463 Gene_expression of CX3CL1 55 0.62 69.05 19.75 5.00
106 INT101188 Gene_expression of Rela 81 0.56 23.43 19.15 5.00
107 INT75742 Binding of RLS 86 0.42 95.27 19.04 5.00
108 INT78024 Gene_expression of ACLY 73 0.75 59.15 18.54 5.00
109 INT103469 Positive_regulation of Gene_expression of BDNF 59 0.67 24.39 18.36 5.00
110 INT50972 Negative_regulation of Ntrk1 39 0.51 32.22 17.29 5.00
111 INT16624 Localization of Grin1 38 0.79 8.46 17.15 5.00
112 INT170033 Positive_regulation of Gene_expression of Fig4 59 0.43 20.99 16.69 5.00
113 INT66023 Positive_regulation of Gene_expression of Itgam 25 0.64 12.65 16.56 5.00
114 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 5.00
115 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 5.00
116 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 5.00
117 INT93482 Localization of Rela 56 0.78 24.52 14.82 5.00
118 INT5904 Localization of MPO 62 0.81 36.37 14.64 5.00
119 INT105156 Phosphorylation of Gfap 23 0.79 11.85 13.76 5.00
120 INT144646 Positive_regulation of Rela 53 0.67 27.78 13.2 5.00
121 INT100655 Regulation of BDNF 51 0.60 21.49 13.14 5.00
122 INT174844 Binding of Fig4 81 0.41 18.03 12.87 5.00
123 INT119089 Regulation of Phosphorylation of Grin1 17 0.61 3.1 12.82 5.00
124 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 5.00
125 INT48335 Negative_regulation of NOSTRIN 38 0.56 16.22 12.05 5.00
126 INT102272 Regulation of TH1L 41 0.44 30.89 11.63 5.00
127 INT50933 Transcription of Il6 38 0.72 24.31 11.58 5.00
128 INT176607 Gene_expression of Cx3cl1 27 0.75 19.51 11.32 5.00
129 INT73959 Positive_regulation of NOSTRIN 49 0.61 31.1 11.27 5.00
130 INT78567 Positive_regulation of Gene_expression of Th 25 0.68 5.32 10.75 5.00
131 INT74681 Positive_regulation of Gene_expression of Mmp2 23 0.55 15.58 10.74 5.00
132 INT72579 Localization of BDNF 56 0.80 14.84 10.65 5.00
133 INT85048 Regulation of NGF 19 0.62 11.61 10.5 5.00
134 INT50196 Transcription of Il1b 25 0.69 19.08 10.43 5.00
135 INT130867 Gene_expression of TNFSF11 106 0.77 45.15 10.34 5.00
136 INT952 Negative_regulation of GHRH 57 0.56 25.3 10.34 5.00
137 INT108098 Positive_regulation of Itgam 19 0.70 8.09 8.86 5.00
138 INT591 Negative_regulation of Serpinc1 44 0.57 31.73 8.82 5.00
139 INT2921 Positive_regulation of F8 53 0.59 41.56 8.56 5.00
140 INT77795 Localization of Gdnf 26 0.81 6.29 8.55 5.00
141 INT2225 Binding of Gfap 31 0.47 11.78 8.53 5.00
142 INT111533 Positive_regulation of Gene_expression of Nfkb1 27 0.52 17.32 7.89 5.00
143 INT66987 Regulation of Th 23 0.61 7.86 6.8 5.00
144 INT62509 Gene_expression of MCS 58 0.67 21.46 6.57 5.00
145 INT105157 Positive_regulation of Phosphorylation of Gfap 8 0.67 6.48 6.38 5.00
146 INT75832 Positive_regulation of Positive_regulation of IL8 30 0.70 20.77 6.05 5.00
147 INT13396 Gene_expression of DMD 125 0.75 57.81 5.45 5.00
148 INT21956 Negative_regulation of Mmp7 12 0.34 7.32 5.34 5.00
149 INT137179 Positive_regulation of CXCL9 11 0.65 7.73 5.11 5.00
150 INT10889 Gene_expression of F8 60 0.78 41.36 5.06 5.00
151 INT60066 Positive_regulation of NPEPPS 17 0.22 11.99 4.83 5.00
152 INT129856 Positive_regulation of TNFRSF11A 26 0.68 16.21 4.75 5.00
153 INT5838 Negative_regulation of Positive_regulation of Gfap 10 0.58 6.52 4.39 5.00
154 INT93016 Binding of TNFRSF11A 29 0.47 19.67 4.17 5.00
155 INT88867 Localization of MCS 19 0.62 28.31 3.88 5.00
156 INT121106 Binding of Slmap 10 0.37 5.19 3.71 5.00
157 INT38561 Regulation of SEMG1 19 0.51 3.75 3.66 5.00
158 INT16165 Regulation of DMD 114 0.60 35.13 3.64 5.00
159 INT102516 Gene_expression of Map2 29 0.69 6.73 3.41 5.00
160 INT122051 Negative_regulation of ROM1 17 0.48 9.11 3.38 5.00
161 INT14994 Positive_regulation of Localization of MPO 12 0.70 6.85 3.37 5.00
162 INT14397 Gene_expression of Serpinc1 27 0.46 14.54 3.32 5.00
163 INT196710 Positive_regulation of VMO1 9 0.64 3.49 3.08 5.00
164 INT24902 Gene_expression of SP1 17 0.71 8.11 2.58 5.00
165 INT4686 Gene_expression of Cys1 32 0.66 36.24 2.49 5.00
166 INT173592 Binding of COL5A2 32 0.33 9.14 2.48 5.00
167 INT324955 Phosphorylation of Itgam 1 0.37 1.96 2.4 5.00
168 INT145970 Negative_regulation of MSD 11 0.50 4.7 2.26 5.00
169 INT233102 Regulation of VMO1 4 0.34 2.7 2.25 5.00
170 INT158123 Negative_regulation of Gene_expression of COL5A2 19 0.46 15.27 2.23 5.00
171 INT140298 Positive_regulation of Myo5c 2 0.03 2.1 2.16 5.00
172 INT228442 Localization of Cntf 8 0.63 4.2 2.12 5.00
173 INT263046 Negative_regulation of Gene_expression of Mmp2 7 0.34 5.98 2.09 5.00
174 INT113415 Positive_regulation of gp 8 0.28 1.62 2.07 5.00
175 INT103095 Binding of ISYNA1 10 0.28 6.17 2.03 5.00
176 INT37216 Binding of SMN1 11 0.36 6.66 1.86 5.00
177 INT166311 Positive_regulation of Gene_expression of LBP 7 0.49 4.15 1.81 5.00
178 INT59790 Binding of BCR 16 0.36 15.34 1.75 5.00
179 INT111890 Binding of MSD 26 0.41 8.05 1.71 5.00
180 INT112081 Negative_regulation of Vsig2 9 0.34 2.37 1.69 5.00
181 INT19747 Regulation of Egf 14 0.46 4.67 1.68 5.00
182 INT182643 Binding of TNFSF11 15 0.35 13.12 1.61 5.00
183 INT154309 Gene_expression of gp 18 0.66 6.79 1.58 5.00
184 INT109881 Positive_regulation of Gene_expression of F8 11 0.47 12.97 1.54 5.00
185 INT167070 Positive_regulation of Gene_expression of MCS 3 0.30 3.75 1.48 5.00
186 INT196714 Binding of VMO1 4 0.30 1.51 1.46 5.00
187 INT302990 Protein_catabolism of MBP 5 0.88 3.75 1.42 5.00
188 INT4928 Binding of Mag 9 0.26 7.62 1.42 5.00
189 INT60860 Gene_expression of Slmap 32 0.66 8.55 1.34 5.00
190 INT125897 Binding of Mmp9 3 0.36 2.36 1.32 5.00
191 INT155509 Binding of Myo5c 2 0.00 0.85 1.25 5.00
192 INT11203 Gene_expression of BCR 30 0.75 33.49 1.22 5.00
193 INT124069 Localization of Ntrk1 9 0.59 3.32 1.13 5.00
194 INT28493 Positive_regulation of IL1RL1 10 0.47 3.44 1.11 5.00
195 INT121526 Localization of PCS 12 0.61 6.47 1.1 5.00
196 INT178674 Positive_regulation of RNGTT 6 0.15 1.05 1.09 5.00
197 INT112082 Regulation of Vsig2 13 0.40 1.89 0.98 5.00
198 INT69132 Negative_regulation of ACLY 5 0.42 2.95 0.92 5.00
199 INT58928 Gene_expression of OCA2 6 0.65 2.04 0.9 5.00
200 INT238271 Binding of WSN 2 0.04 2.61 0.81 5.00
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