D:Autonomic Dysreflexia

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pChart

Disease Term
Synonyms AUTONOMIC DYSREFLEXIA SPINAL, Autonomic Dysreflexias, Autonomic Dysreflexias Spinal, Autonomic Hyperreflexia, Autonomic Hyperreflexias, Dysreflexia Autonomic, Dysreflexia Spinal Autonomic, Dysreflexias Autonomic, Dysreflexias Spinal Autonomic, Hyperreflexia Autonomic, HYPERREFLEXIAS AUTONOMIC
Documents 168
Hot Single Events 15
Hot Interactions 4

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Autonomic Dysreflexia. They are ordered first by their relevance to Autonomic Dysreflexia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT108065 Negative_regulation of Binding of Ngf and IgG-2a 1 0.01 2.38 1.2 99.96
2 INT108067 Negative_regulation of Binding of NTRK1 and Ngf 1 0.06 2.38 1.2 99.96
3 INT108064 Binding of Ngf and IgG-2a 1 0.01 2.36 1.19 98.76
4 INT108066 Binding of NTRK1 and Ngf 3 0.33 2.56 1.66 98.60
5 INT137441 Ngf Negative_regulation of Sema3a 1 0.46 2.07 1.01 5.00
6 INT137438 Ntf3 Regulation of Sema3a 1 0.06 0.82 0.35 5.00
7 INT137437 Nrtn Regulation of Sema3a 1 0.36 0.82 0.35 5.00
8 INT137439 Ntf3 Negative_regulation of Sema3a 1 0.02 0.77 0.34 5.00
9 INT137442 Nrtn Regulation of Sema3a 1 0.04 0.81 0.34 5.00
10 INT137440 Nrtn Negative_regulation of Sema3a 1 0.34 0.77 0.34 5.00
11 INT327845 Binding of Aqp9 and Ooep 1 0.00 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Autonomic Dysreflexia. They are ordered first by their pain relevance and then by number of times they were reported in Autonomic Dysreflexia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT19466 Negative_regulation of Clcn1 6 0.52 3.39 1.22 100.00
2 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 99.00
3 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 99.00
4 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19 98.76
5 INT14849 Binding of IgG-2a 12 0.39 5.96 6.06 98.76
6 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 95.76
7 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 93.52
8 INT4073 Localization of Dbh 28 0.81 6.06 16.37 92.32
9 INT71867 Positive_regulation of Fes 1 0.40 0.72 0.17 92.28
10 INT79902 Gene_expression of AQP1 33 0.78 24.72 4.55 90.40
11 INT2960 Regulation of Dbh 32 0.47 10.32 18.94 90.32
12 INT20422 Regulation of Gap43 10 0.61 5.24 3.73 90.32
13 INT211054 Positive_regulation of AQP1 3 0.33 4.53 1.41 87.72
14 INT134304 Positive_regulation of Sema3a 1 0.50 1.23 0.59 85.48
15 INT19078 Binding of Ngf 78 0.48 31.03 44.33 84.72
16 INT52184 Gene_expression of Sema3a 8 0.55 3.97 3.72 79.76
17 INT72647 Positive_regulation of Gene_expression of Sema3a 3 0.40 1.98 1.52 79.76
18 INT10240 Gene_expression of Gap43 58 0.78 22.11 24.45 79.36
19 INT14436 Gene_expression of Dbh 42 0.72 9.9 19.85 78.04
20 INT4958 Gene_expression of Pcyt1b 18 0.65 3.4 5.66 75.00
21 INT157399 Localization of Pcyt1b 9 0.69 2.3 2.54 75.00
22 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 75.00
23 INT109650 Gene_expression of Aqp4 87 0.78 51.52 20.72 68.28
24 INT156132 Gene_expression of Aqp9 26 0.49 14.33 3.48 68.28
25 INT2429 Negative_regulation of Mpo 128 0.59 93.76 39.57 67.60
26 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 62.00
27 INT327786 Negative_regulation of Gene_expression of AQP1 3 0.29 4.21 0.44 59.36
28 INT9310 Negative_regulation of Ssr1 20 0.49 6.55 4.73 56.68
29 INT14502 Gene_expression of BCHE 40 0.67 18.52 4.6 55.92
30 INT47027 Positive_regulation of BCHE 6 0.50 2.32 1.09 55.92
31 INT47026 Positive_regulation of Gene_expression of BCHE 1 0.44 0.23 0.34 55.92
32 INT34720 Positive_regulation of SHBG 58 0.69 32.4 3.83 55.24
33 INT122041 Binding of Ppara 308 0.48 189.17 51.48 54.24
34 INT58919 Localization of Gap43 10 0.78 3.53 4.61 47.76
35 INT118202 Negative_regulation of Itgb2 1 0.41 1.05 0.42 45.32
36 INT118201 Negative_regulation of Itgam 3 0.22 3.41 1.99 45.12
37 INT156346 Negative_regulation of Itga4 1 0.02 0.57 0.4 43.88
38 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
39 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 5.00
40 INT1303 Negative_regulation of Npr1 278 0.55 35.1 156.78 5.00
41 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 5.00
42 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
43 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
44 INT16258 Gene_expression of Ntf3 121 0.78 53.93 59.03 5.00
45 INT4345 Gene_expression of Gtf3a 157 0.67 80.75 48.47 5.00
46 INT11439 Positive_regulation of Csf2 105 0.69 62.63 37.77 5.00
47 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
48 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45 5.00
49 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
50 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55 5.00
51 INT17825 Gene_expression of Flvcr2 44 0.68 12.58 28.08 5.00
52 INT5622 Gene_expression of Nppa 101 0.78 49.46 25.31 5.00
53 INT48144 Gene_expression of Fgf2 117 0.78 43 20.48 5.00
54 INT47689 Positive_regulation of Ntrk2 44 0.68 16.84 19.59 5.00
55 INT3521 Regulation of Csf2 38 0.54 11.09 12.73 5.00
56 INT80790 Positive_regulation of Flvcr2 22 0.45 4.92 12.35 5.00
57 INT112003 Localization of ROS1 94 0.73 66.32 12.16 5.00
58 INT109651 Negative_regulation of Aqp4 23 0.53 8.5 10.7 5.00
59 INT22132 Positive_regulation of CAT 41 0.67 18.64 10.67 5.00
60 INT69867 Gene_expression of Mip 36 0.75 24.54 10.38 5.00
61 INT17824 Positive_regulation of Gene_expression of Flvcr2 15 0.41 6.66 10.23 5.00
62 INT149069 Positive_regulation of Cxcr4 24 0.68 12.21 9.54 5.00
63 INT71689 Localization of Ntf3 23 0.73 11.1 7.91 5.00
64 INT138799 Regulation of Gene_expression of Ppara 40 0.60 29.42 6.89 5.00
65 INT136309 Positive_regulation of Cxcl12 24 0.62 12.45 5.58 5.00
66 INT91147 Positive_regulation of Positive_regulation of Ppara 30 0.69 19.31 5.56 5.00
67 INT69350 Gene_expression of RAC1 23 0.77 12.16 5.54 5.00
68 INT155349 Positive_regulation of Gene_expression of Aqp4 8 0.70 6.26 2.94 5.00
69 INT152961 Negative_regulation of Gene_expression of Aqp4 13 0.59 10.01 2.92 5.00
70 INT262476 Gene_expression of Aqp8 21 0.34 7.94 2.76 5.00
71 INT262474 Gene_expression of Aqp6 26 0.77 2.08 2.49 5.00
72 INT215379 Positive_regulation of Binding of Ppara 15 0.66 8.04 2.36 5.00
73 INT54277 Gene_expression of Ppbp 9 0.06 1.19 2.19 5.00
74 INT2611 Negative_regulation of AQP1 17 0.39 10.04 2.15 5.00
75 INT70987 Binding of RAC1 14 0.37 12.14 2.13 5.00
76 INT104564 Gene_expression of Aqp3 8 0.65 4.92 1.99 5.00
77 INT210590 Positive_regulation of Gene_expression of Mip 10 0.67 8.09 1.68 5.00
78 INT12442 Localization of Vegfa 11 0.73 4.85 1.68 5.00
79 INT110906 Binding of Rorb 14 0.48 2.88 1.62 5.00
80 INT69863 Binding of Mip 7 0.36 4.54 1.33 5.00
81 INT100328 Gene_expression of AQP2 6 0.75 2.41 1.21 5.00
82 INT1867 Positive_regulation of GABBR1 6 0.69 0.55 1.18 5.00
83 INT235939 Gene_expression of Aqp5 8 0.45 4.7 1.06 5.00
84 INT166889 Positive_regulation of Gene_expression of AQP1 10 0.70 6.43 0.99 5.00
85 INT249847 Positive_regulation of Msc 6 0.26 3.36 0.84 5.00
86 INT191926 Negative_regulation of Lepr 13 0.48 17.68 0.8 5.00
87 INT241788 Positive_regulation of Gene_expression of AQP2 3 0.67 1.26 0.7 5.00
88 INT103942 Binding of BPHL 11 0.30 14.26 0.53 5.00
89 INT135987 Regulation of Sema3a 2 0.60 0.57 0.43 5.00
90 INT130571 Gene_expression of Flt4 7 0.27 6.61 0.37 5.00
91 INT327840 Gene_expression of Aqp11 1 0.29 7.24 0.33 5.00
92 INT262487 Positive_regulation of Gene_expression of Aqp9 6 0.32 5.29 0.24 5.00
93 INT262488 Gene_expression of Aqp7 2 0.31 0.73 0.16 5.00
94 INT262482 Positive_regulation of Gene_expression of Aqp6 3 0.46 0.14 0.14 5.00
95 INT327838 Negative_regulation of Aqp9 1 0.27 0.78 0.12 5.00
96 INT262484 Positive_regulation of Gene_expression of Aqp8 2 0.22 0.33 0.12 5.00
97 INT179117 Positive_regulation of Nrp1 4 0.28 2.08 0.08 5.00
98 INT345025 Regulation of Localization of Rtn4rl2 1 0.01 0.62 0.07 5.00
99 INT327839 Localization of Aqp7 1 0.24 0.59 0.07 5.00
100 INT345024 Localization of Rtn4rl2 1 0.02 0.62 0.07 5.00
101 INT327837 Negative_regulation of Aqp5 1 0.18 1.48 0.07 5.00
102 INT289825 Positive_regulation of Aqp6 2 0.21 0.62 0.07 5.00
103 INT327833 Binding of Aqp11 1 0.14 1.15 0.06 5.00
104 INT299236 Gene_expression of AQP10 2 0.27 1.59 0.04 5.00
105 INT327841 Localization of Aqp5 1 0.34 0.67 0.04 5.00
106 INT327832 Negative_regulation of Aqp3 1 0.17 0 0.04 5.00
107 INT327836 Gene_expression of Aqp12 1 0.32 1.04 0.03 5.00
108 INT327835 Gene_expression of Ooep 1 0.01 0.12 0 5.00
109 INT327834 Positive_regulation of Gene_expression of Aqp5 1 0.21 0 0 5.00
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