D:Autosomal Disorder

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Disease Term
Synonyms Autosomal Chromosome Disorder, AUTOSOMAL CHROMOSOME DISORDERS, Autosomal Disorders, Autosomal Syndrome, Autosomal Syndromes, AUTOSOMAL TRAIT DISORDER, Autosomal Trait Disorders, CHROMOSOMAL DISORDER, Chromosomal Disorders, Chromosome Abnormality Disorder, Chromosome Abnormality Disorders
Documents 47
Hot Single Events 11
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Autosomal Disorder. They are ordered first by their relevance to Autosomal Disorder and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT339020 SERPINA1 Negative_regulation of ELANE 1 0.07 0.59 0.05 76.40
2 INT230461 Binding of TLR1 and TLR2 3 0.33 2.06 0.43 5.00
3 INT230460 Binding of TLR2 and TLR6 2 0.07 1.9 0.25 5.00
4 INT277112 Binding of AMD1 and CFH 1 0.16 2.45 0.18 5.00
5 INT230464 Binding of SNRNP70 and TLR1 1 0.02 1.2 0.17 5.00
6 INT230463 Binding of MT1JP and TLR2 1 0.02 0.44 0.12 5.00
7 INT230459 Binding of MLLT1 and TLR1 1 0.07 0.81 0.1 5.00
8 INT230465 Binding of TLR1 and TH1L 1 0.09 0.99 0.08 5.00
9 INT230462 Binding of SNRNP70 and TH1L 1 0.00 0.99 0.08 5.00
10 INT353795 Binding of Cd320 and Apob 1 0.08 0.82 0 5.00
11 INT286113 Binding of Fap and Rpe65 1 0.04 1.97 0 5.00
12 INT286114 Binding of MSH6 and Mutyh 1 0.17 0 0 5.00
13 INT306677 Binding of Mapt and Atxn3 1 0.07 0.49 0 5.00
14 INT353798 Binding of Hdl1 and Apob 1 0.01 0.82 0 5.00
15 INT286111 Binding of Rpa3 and Mutyh 1 0.30 0 0 5.00
16 INT353799 Binding of Cd320 and Hdl1 1 0.03 0.83 0 5.00
17 INT239913 Binding of C7 and C8B 1 0.18 0.06 0 5.00
18 INT286112 Binding of Apc and Afap1 1 0.05 0.71 0 5.00
19 INT286110 Binding of Rpe65 and Gopc 1 0.01 1.97 0 5.00
20 INT353802 Binding of APOE and Apob 1 0.05 0.83 0 5.00
21 INT286115 Binding of APEX1 and Mutyh 1 0.10 0 0 5.00
22 INT322931 Binding of MOCS1 and Litaf 1 0.00 0.82 0 5.00
23 INT353801 Binding of APOE and Cd320 1 0.22 0.83 0 5.00
24 INT353796 Binding of Ldlr and Apob 1 0.06 0.82 0 5.00
25 INT353804 Binding of APOE and Ldlr 1 0.16 0.84 0 5.00
26 INT286109 Binding of Pcna and Mutyh 1 0.30 0 0 5.00
27 INT251822 Binding of POLG and C10orf2 1 0.42 0.29 0 5.00
28 INT353797 Binding of Ldlr and Trf 1 0.04 0.19 0 5.00
29 INT353800 Binding of Ldlr and Cd320 1 0.29 0.83 0 5.00
30 INT353803 Binding of APOE and Hdl1 1 0.01 0.83 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Autosomal Disorder. They are ordered first by their pain relevance and then by number of times they were reported in Autosomal Disorder. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT171686 Binding of asp1 8 0.31 11.88 1.07 99.24
2 INT98644 Transcription of FGF23 1 0.41 2.83 0.17 96.72
3 INT98641 Transcription of Phex 1 0.23 2.89 0.17 96.72
4 INT98645 Gene_expression of FGF23 9 0.78 10.07 0.8 96.20
5 INT70602 Regulation of Phex 3 0.13 1.51 1.06 91.88
6 INT67624 Gene_expression of Phex 3 0.26 4.15 1.67 91.00
7 INT98643 Positive_regulation of Gene_expression of FGF23 2 0.47 2.16 0.13 82.96
8 INT98639 Positive_regulation of Gene_expression of Phex 1 0.24 1.26 0.06 82.96
9 INT2609 Localization of ELANE 111 0.81 50.22 26.63 82.12
10 INT142800 Positive_regulation of Ldlr 21 0.68 14.75 0.6 81.24
11 INT179300 Negative_regulation of TGFB1I1 1 0.06 1.92 0 80.40
12 INT53261 Gene_expression of exf 5 0.07 4.93 1.24 74.92
13 INT14204 Protein_catabolism of KNG1 41 0.96 20.94 11.47 72.04
14 INT98642 Binding of FGF23 1 0.22 1.46 0.09 67.28
15 INT68216 Binding of NF1 40 0.48 51.24 4.59 66.80
16 INT98640 Binding of Phex 1 0.13 1.44 0.09 66.00
17 INT194465 Gene_expression of Ldlr 27 0.76 31.36 2.73 65.76
18 INT252223 Positive_regulation of Gene_expression of Ldlr 3 0.55 10.28 0.37 65.76
19 INT251830 Binding of TYMP 2 0.13 4.36 0.37 65.32
20 INT48766 Regulation of NOS1 73 0.61 37.01 24.59 58.48
21 INT134945 Binding of GBA 3 0.37 3.69 0.24 57.36
22 INT230467 Gene_expression of MT1JP 23 0.62 24.26 0.83 56.32
23 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 49.68
24 INT18156 Gene_expression of Fap 18 0.73 27.02 1.46 45.48
25 INT239934 Gene_expression of PSG5 2 0.37 0 0 42.60
26 INT322929 Positive_regulation of Gene_expression of CHIT1 1 0.07 6.12 0.83 42.08
27 INT241797 Gene_expression of CHIT1 10 0.24 9.75 0.69 41.28
28 INT57278 Localization of SERPINA1 4 0.81 2.59 0.21 41.08
29 INT4391 Gene_expression of SERPINA1 47 0.78 41.43 9.7 40.44
30 INT3076 Regulation of KNG1 52 0.60 20.39 27.89 37.76
31 INT14205 Regulation of KLK1 10 0.60 4.38 1.28 37.76
32 INT174106 Binding of Renbp 18 0.24 15.82 0.58 31.68
33 INT282982 Binding of Map1lc3a 4 0.28 1.77 0.03 28.88
34 INT306658 Binding of Map1lc3b 2 0.13 0.2 0 28.88
35 INT89678 Positive_regulation of Gene_expression of PRKG1 15 0.70 5.99 3.84 25.84
36 INT105865 Regulation of Gene_expression of PRKG1 4 0.12 1.82 1.15 25.84
37 INT75540 Positive_regulation of TH1L 62 0.67 43.45 15.02 25.00
38 INT129425 Negative_regulation of Ldlr 22 0.42 17.15 0.97 25.00
39 INT89677 Gene_expression of PRKG1 38 0.78 13.98 8.56 24.80
40 INT157302 Positive_regulation of Map1lc3a 27 0.66 11.31 0.79 18.52
41 INT254881 Negative_regulation of Atg7 9 0.34 5.69 0.32 10.32
42 INT306663 Negative_regulation of Atg5 1 0.10 0.28 0 10.32
43 INT97453 Negative_regulation of MOCS1 25 0.04 13.4 2.4 10.16
44 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 5.00
45 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 5.00
46 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 5.00
47 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
48 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71 5.00
49 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35 5.00
50 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 5.00
51 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57 5.00
52 INT66331 Gene_expression of Cacna1a 101 0.78 49.58 46.32 5.00
53 INT17561 Localization of Car2 303 0.79 60.95 44.52 5.00
54 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 5.00
55 INT26698 Positive_regulation of Cacna1a 37 0.67 26.33 39.1 5.00
56 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 5.00
57 INT169180 Binding of SNRNP70 204 0.47 119.1 29.3 5.00
58 INT67585 Gene_expression of UGT2B7 52 0.78 2.33 24.13 5.00
59 INT6441 Positive_regulation of CRH 98 0.69 57.22 24.12 5.00
60 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06 5.00
61 INT5905 Negative_regulation of ELANE 113 0.59 47.43 22.09 5.00
62 INT139664 Gene_expression of CCL18 83 0.76 37.05 21.95 5.00
63 INT23564 Negative_regulation of Car2 103 0.50 27.28 21.86 5.00
64 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66 5.00
65 INT31136 Binding of Cacna1a 28 0.45 30.76 17.35 5.00
66 INT9197 Binding of PTGS1 44 0.48 18.48 16.26 5.00
67 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31 5.00
68 INT16919 Gene_expression of IL36RN 48 0.48 32.78 13.83 5.00
69 INT26545 Gene_expression of Hras1 173 0.78 79.54 13.21 5.00
70 INT105670 Gene_expression of AAVS1 131 0.75 49.24 12.95 5.00
71 INT59080 Negative_regulation of Gene_expression of PTGS2 55 0.58 22.92 12.39 5.00
72 INT150540 Binding of TLR2 50 0.45 35.86 10.43 5.00
73 INT10049 Negative_regulation of SERPINA1 56 0.59 44.52 9.93 5.00
74 INT6511 Positive_regulation of AFP 76 0.70 70.15 7.28 5.00
75 INT159518 Gene_expression of Clock 4 0.35 2.34 6.91 5.00
76 INT5864 Localization of IL36RN 19 0.44 14.5 6.87 5.00
77 INT31582 Gene_expression of Hdl1 103 0.66 118.95 6.42 5.00
78 INT57256 Gene_expression of HLA-DQA2 52 0.55 23.87 6.27 5.00
79 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21 5.00
80 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02 5.00
81 INT30195 Gene_expression of Ubqln1 12 0.10 1.09 5.89 5.00
82 INT146808 Positive_regulation of CCL18 25 0.69 11.98 5.71 5.00
83 INT139749 Regulation of Ubqln1 10 0.02 2.47 5.38 5.00
84 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22 5.00
85 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19 5.00
86 INT129508 Localization of Cacna1a 7 0.74 6.47 5.13 5.00
87 INT201130 Localization of AES 31 0.63 25.45 5.12 5.00
88 INT10694 Binding of Bche 19 0.48 8.03 4.85 5.00
89 INT26546 Positive_regulation of Gene_expression of Hras1 35 0.70 16.59 4.54 5.00
90 INT141000 Negative_regulation of GSK 24 0.57 9.46 4.4 5.00
91 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91 5.00
92 INT68695 Gene_expression of HTT 63 0.77 44.54 3.69 5.00
93 INT17685 Negative_regulation of Cog1 23 0.42 15.65 3.56 5.00
94 INT100384 Regulation of SNRNP70 24 0.60 11 3.56 5.00
95 INT200443 Positive_regulation of AES 27 0.60 22.46 3.22 5.00
96 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19 5.00
97 INT43907 Binding of CD79A 28 0.48 28.11 3.04 5.00
98 INT9055 Positive_regulation of Cog1 22 0.68 14.08 2.95 5.00
99 INT172177 Protein_catabolism of INCENP 18 0.37 6.34 2.91 5.00
100 INT134795 Positive_regulation of Scrib 30 0.22 36.91 2.81 5.00
101 INT50080 Binding of APOE 38 0.45 29.61 2.67 5.00
102 INT145328 Negative_regulation of Scrib 25 0.16 26.79 2.66 5.00
103 INT133029 Regulation of TLR2 18 0.56 11.31 2.62 5.00
104 INT210058 Regulation of ELF3 11 0.29 7.93 2.51 5.00
105 INT16964 Binding of IFNG 27 0.48 14.31 2.45 5.00
106 INT10048 Positive_regulation of SERPINA1 11 0.68 8.59 2.43 5.00
107 INT192541 Gene_expression of Tg(Foxn1)E1Hon 20 0.20 8.98 2.4 5.00
108 INT150476 Positive_regulation of ELF3 32 0.56 13.61 2.39 5.00
109 INT55952 Transcription of TP53 16 0.61 12.14 2.36 5.00
110 INT105669 Positive_regulation of Gene_expression of AAVS1 20 0.49 9.02 2.06 5.00
111 INT8792 Gene_expression of GBA 20 0.78 14.73 1.98 5.00
112 INT65880 Gene_expression of CYP2C8 25 0.77 9.49 1.92 5.00
113 INT222903 Gene_expression of TLR1 20 0.60 8.77 1.9 5.00
114 INT183753 Regulation of HBM 24 0.39 13.13 1.79 5.00
115 INT36529 Gene_expression of Mela 39 0.69 12.05 1.73 5.00
116 INT3818 Regulation of Apc 13 0.39 12.52 1.68 5.00
117 INT95134 Binding of TH1L 6 0.47 3.67 1.68 5.00
118 INT195970 Binding of Atp1a2 2 0.34 2.31 1.66 5.00
119 INT6830 Positive_regulation of Notch1 20 0.55 7.91 1.57 5.00
120 INT223091 Gene_expression of ELF3 45 0.62 17.9 1.56 5.00
121 INT189302 Positive_regulation of Gene_expression of HLA-DQA2 6 0.06 4.44 1.48 5.00
122 INT46736 Negative_regulation of Odc1 10 0.51 7.6 1.39 5.00
123 INT108325 Gene_expression of Scrib 26 0.39 48.33 1.39 5.00
124 INT220177 Binding of Apc 21 0.37 15.34 1.37 5.00
125 INT172452 Gene_expression of Myc 121 0.78 69.56 1.36 5.00
126 INT79357 Binding of ERVW-1 32 0.43 16.06 1.35 5.00
127 INT95939 Positive_regulation of GSK 19 0.67 10 1.33 5.00
128 INT197143 Positive_regulation of Renbp 15 0.33 9.41 1.31 5.00
129 INT110434 Positive_regulation of Gene_expression of Apc 20 0.50 11.37 1.3 5.00
130 INT22513 Gene_expression of asp1 8 0.58 4.36 1.26 5.00
131 INT128176 Regulation of RHOA 13 0.44 4.35 1.26 5.00
132 INT15502 Regulation of asp1 6 0.19 2.29 1.2 5.00
133 INT228648 Binding of Scn1a 1 0.27 1.95 1.15 5.00
134 INT108559 Gene_expression of Pol 46 0.45 30.07 1.14 5.00
135 INT205618 Gene_expression of Renbp 15 0.26 9.26 1.04 5.00
136 INT151774 Positive_regulation of Mtor 38 0.45 20.15 1.01 5.00
137 INT136831 Gene_expression of Nodal 6 0.22 5.68 0.97 5.00
138 INT170163 Negative_regulation of ACSM3 5 0.16 3.56 0.96 5.00
139 INT23660 Negative_regulation of Fap 5 0.35 8.93 0.95 5.00
140 INT10827 Gene_expression of Apob 16 0.78 13.08 0.9 5.00
141 INT10828 Regulation of Apob 7 0.39 7.55 0.83 5.00
142 INT121334 Binding of HTT 11 0.47 6.66 0.78 5.00
143 INT51739 Negative_regulation of Apob 9 0.42 4.21 0.78 5.00
144 INT131384 Binding of Mutyh 5 0.26 2.41 0.78 5.00
145 INT129115 Negative_regulation of Cdkn2a 16 0.50 17.03 0.76 5.00
146 INT28869 Regulation of Ear11 3 0.18 1.62 0.75 5.00
147 INT214860 Binding of GYPC 10 0.36 11.18 0.74 5.00
148 INT57062 Regulation of APC 24 0.58 14.3 0.7 5.00
149 INT46392 Regulation of SERPINA1 4 0.44 2.23 0.68 5.00
150 INT145384 Binding of LTA 10 0.32 4.4 0.66 5.00
151 INT142802 Binding of Ldlr 8 0.47 5.08 0.65 5.00
152 INT158136 Binding of FGFR2 9 0.26 4.5 0.63 5.00
153 INT133589 Negative_regulation of Pol 6 0.25 2.84 0.61 5.00
154 INT142184 Regulation of TXK 10 0.11 8.25 0.59 5.00
155 INT69478 Negative_regulation of GBA 16 0.55 7.9 0.59 5.00
156 INT192841 Binding of Mela 9 0.43 4.29 0.58 5.00
157 INT114519 Gene_expression of Hcm 10 0.57 13.01 0.57 5.00
158 INT202940 Binding of AMD1 13 0.41 16.43 0.56 5.00
159 INT107652 Gene_expression of C7 4 0.60 2.06 0.56 5.00
160 INT205619 Regulation of Renbp 6 0.17 1.91 0.55 5.00
161 INT327116 Positive_regulation of Localization of AES 4 0.22 2.69 0.55 5.00
162 INT212966 Negative_regulation of Gene_expression of Hdl1 8 0.27 10.98 0.49 5.00
163 INT91977 Gene_expression of GRHL1 5 0.04 1.23 0.48 5.00
164 INT183629 Gene_expression of Ctnnd2 14 0.75 11.78 0.48 5.00
165 INT151720 Negative_regulation of Positive_regulation of Apc 3 0.37 2.15 0.46 5.00
166 INT214067 Regulation of Scrib 11 0.20 12.48 0.45 5.00
167 INT58679 Gene_expression of Odc1 13 0.78 9.55 0.45 5.00
168 INT114767 Gene_expression of TAS1R2 3 0.75 0.39 0.45 5.00
169 INT241799 Negative_regulation of CHIT1 13 0.42 4.37 0.44 5.00
170 INT147176 Gene_expression of SULT1C3 8 0.78 0.69 0.44 5.00
171 INT198884 Gene_expression of Vldlr 13 0.70 2.41 0.44 5.00
172 INT238793 Gene_expression of Cbl 6 0.03 3.01 0.43 5.00
173 INT251828 Negative_regulation of C10orf2 3 0.37 2.87 0.41 5.00
174 INT15762 Negative_regulation of asp1 6 0.37 0.71 0.4 5.00
175 INT73627 Binding of Fap 8 0.36 11.14 0.4 5.00
176 INT27554 Regulation of Eln 6 0.52 6.76 0.39 5.00
177 INT230469 Binding of TLR1 6 0.40 1.81 0.38 5.00
178 INT206440 Binding of MOCS1 13 0.01 3.76 0.35 5.00
179 INT46843 Binding of Trf 10 0.47 3.45 0.35 5.00
180 INT121073 Gene_expression of NMUR1 2 0.15 0.85 0.35 5.00
181 INT1626 Binding of Cog1 8 0.21 7.86 0.34 5.00
182 INT134943 Localization of MOCS1 7 0.07 4.23 0.34 5.00
183 INT232235 Negative_regulation of Gene_expression of Ldlr 3 0.42 3.13 0.34 5.00
184 INT125227 Positive_regulation of CHIT1 5 0.21 3.52 0.33 5.00
185 INT225667 Transcription of Apc 3 0.52 3.73 0.32 5.00
186 INT182073 Binding of APEX1 4 0.12 1.72 0.32 5.00
187 INT187410 Localization of Cd320 14 0.78 9.03 0.31 5.00
188 INT241802 Regulation of GBA 2 0.39 2.27 0.3 5.00
189 INT9054 Negative_regulation of Positive_regulation of Cog1 3 0.08 1.38 0.28 5.00
190 INT190676 Binding of Fkbp1a 15 0.36 3.11 0.28 5.00
191 INT75299 Binding of Atxn3 8 0.43 5.3 0.26 5.00
192 INT134946 Localization of GBA 3 0.75 2.49 0.24 5.00
193 INT138715 Gene_expression of POLG 12 0.66 6.97 0.23 5.00
194 INT171716 Regulation of Fap 4 0.27 4.05 0.23 5.00
195 INT54807 Binding of MLLT1 4 0.11 2.96 0.22 5.00
196 INT262274 Gene_expression of UGCG 8 0.27 1.62 0.22 5.00
197 INT205617 Negative_regulation of Positive_regulation of Renbp 1 0.16 1.04 0.21 5.00
198 INT198492 Localization of Sumo1 3 0.24 0 0.21 5.00
199 INT333881 Gene_expression of GAG 2 0.75 0.4 0.2 5.00
200 INT260174 Gene_expression of Rpe65 29 0.78 4.2 0.19 5.00
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