D:Avian Sarcoma

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Disease Term
Synonyms AVIAN SARCOMAS, ROUS SARCOMA, SARCOMA ROUS, Sarcomas Avian
Documents 25
Hot Single Events 45
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Avian Sarcoma. They are ordered first by their relevance to Avian Sarcoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT351157 TSC1 Positive_regulation of Gene_expression of CAV1 1 0.01 1.43 0 82.16
2 INT351165 Binding of CAV1 and Nos3 1 0.09 1.46 0 72.48
3 INT338900 MYC Positive_regulation of Gene_expression of TP73 1 0.05 0.27 0.03 54.52
4 INT338902 Binding of MAX and MYC 1 0.02 0.23 0.06 49.76
5 INT338898 Binding of PECAM1 and PTPN11 1 0.04 0.38 0.19 5.00
6 INT334590 IRF6 Positive_regulation of Localization of Ptger2 1 0.00 0 0.15 5.00
7 INT338901 Binding of PECAM1 and PTPN6 1 0.03 0.18 0.1 5.00
8 INT280569 Binding of GEM and HIVEP1 1 0.00 1.59 0.03 5.00
9 INT280601 Binding of HIVEP1 and Dbi 1 0.00 1.57 0.03 5.00
10 INT277745 Trib3 Regulation of Ccnd1 1 0.00 0.41 0.03 5.00
11 INT351155 AKT1 Positive_regulation of Positive_regulation of FGF2 1 0.03 0.81 0 5.00
12 INT351167 CAV1 Negative_regulation of Ppp2r1a 1 0.08 1.5 0 5.00
13 INT280568 MRAS Positive_regulation of RAF1 1 0.01 0.7 0 5.00
14 INT351166 Gtf3a Positive_regulation of Gene_expression of CAV1 1 0.01 0.79 0 5.00
15 INT338899 THPO Positive_regulation of STAT3 1 0.16 0 0 5.00
16 INT280566 Binding of ARAF and BCL2 1 0.02 0.69 0 5.00
17 INT351156 VEGFA Positive_regulation of Gene_expression of CAV1 1 0.07 0.79 0 5.00
18 INT284232 Binding of TP53 and HNRNPUL1 1 0.26 0.88 0 5.00
19 INT284231 Binding of TP53 and C4orf3 1 0.02 0.88 0 5.00
20 INT351164 CAV1 Negative_regulation of Ppp1cc 1 0.11 1.5 0 5.00
21 INT351158 CAV1 Regulation of SRC 1 0.01 0.68 0 5.00
22 INT351159 CAV1 Positive_regulation of AKT1 1 0.11 0.87 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Avian Sarcoma. They are ordered first by their pain relevance and then by number of times they were reported in Avian Sarcoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT20345 Gene_expression of Dbi 136 0.78 56.41 46.2 99.84
2 INT47818 Positive_regulation of Homer1 48 0.70 11.11 24.05 99.84
3 INT115223 Positive_regulation of Gene_expression of Prop1 1 0.05 0.4 0.27 99.30
4 INT115221 Gene_expression of Prop1 1 0.07 0.2 0.14 99.02
5 INT34590 Gene_expression of ALPP 199 0.75 89.85 15.1 98.80
6 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 97.96
7 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 97.32
8 INT115222 Positive_regulation of Prop1 1 0.05 0.19 0.14 97.28
9 INT59078 Positive_regulation of Transcription of PTGS2 5 0.69 2.36 1.17 95.80
10 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 95.68
11 INT69878 Positive_regulation of Gene_expression of Gtf3a 48 0.29 36.78 13.57 95.68
12 INT28054 Regulation of Ces2a 4 0.14 1.03 2.16 95.56
13 INT4311 Negative_regulation of Ces2a 5 0.44 1.24 1.14 95.56
14 INT59079 Transcription of PTGS2 30 0.72 14.21 6.52 95.32
15 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 94.84
16 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 93.68
17 INT59080 Negative_regulation of Gene_expression of PTGS2 55 0.58 22.92 12.39 93.68
18 INT52616 Negative_regulation of Positive_regulation of PTGS2 13 0.43 4.95 4.13 93.68
19 INT18759 Positive_regulation of Gene_expression of CYP2E1 22 0.70 5.02 6.84 93.12
20 INT9904 Gene_expression of CYP2E1 64 0.78 13.11 14.65 92.60
21 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 92.24
22 INT172624 Binding of NCOA3 4 0.22 1.05 0.03 90.88
23 INT2389 Regulation of PTGS1 86 0.61 31.23 28.95 90.80
24 INT59077 Transcription of PTGS1 11 0.43 2.37 1.65 90.80
25 INT59081 Regulation of Transcription of PTGS1 1 0.11 0.16 0.21 90.80
26 INT5759 Positive_regulation of Ptgs1 127 0.69 53.45 53.04 90.08
27 INT67975 Gene_expression of Bdkrb2 38 0.68 21.69 17.94 89.08
28 INT153666 Gene_expression of CAV1 156 0.77 120.99 3.9 88.68
29 INT59575 Gene_expression of MGST1 2 0.52 3.47 0.98 88.40
30 INT59576 Positive_regulation of Gene_expression of MGST1 2 0.34 2.07 0.54 88.40
31 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 86.08
32 INT4803 Transcription of Penk 435 0.72 59.09 182.4 85.76
33 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 85.48
34 INT38433 Gene_expression of GRHPR 3 0.06 0.42 0.48 84.64
35 INT59573 Positive_regulation of Gene_expression of GRHPR 1 0.02 0.17 0.05 84.64
36 INT67974 Positive_regulation of Gene_expression of Bdkrb2 3 0.37 1.13 1.12 83.92
37 INT10796 Gene_expression of CYP2B6 131 0.77 30.14 35.27 83.84
38 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66 83.80
39 INT26551 Positive_regulation of Gene_expression of KNG1 19 0.67 11.05 7.98 83.80
40 INT11447 Positive_regulation of DECR1 9 0.67 3.12 4.94 82.48
41 INT9905 Gene_expression of DECR1 11 0.75 2.49 2.43 82.48
42 INT59574 Positive_regulation of Gene_expression of DECR1 1 0.49 0.16 0.05 82.48
43 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81 82.24
44 INT163278 Regulation of Gene_expression of CAV1 5 0.45 4.36 0.14 81.28
45 INT18772 Positive_regulation of Gene_expression of CYP2B6 14 0.49 2.93 5.4 80.48
46 INT153670 Positive_regulation of Gene_expression of CAV1 26 0.69 44.27 0.92 79.56
47 INT163277 Negative_regulation of Gene_expression of CAV1 17 0.56 10.77 0.35 79.20
48 INT29402 Gene_expression of Src 16 0.74 4.57 2.29 78.20
49 INT39516 Gene_expression of Alb 81 0.75 30.08 6.59 78.00
50 INT59572 Localization of MGST1 1 0.19 0.16 0.1 77.40
51 INT9903 Gene_expression of CYB5A 9 0.37 2.78 0.53 73.44
52 INT20420 Gene_expression of MYC 99 0.75 49.32 14.36 71.64
53 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 71.24
54 INT78955 Regulation of Gene_expression of Ptgs2 12 0.62 7.22 6.02 71.12
55 INT7093 Negative_regulation of CYP2B6 146 0.58 37.3 48.39 71.00
56 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 70.72
57 INT105670 Gene_expression of AAVS1 131 0.75 49.24 12.95 70.24
58 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02 70.16
59 INT3167 Binding of KNG1 48 0.48 23.26 26.77 70.00
60 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89 70.00
61 INT76532 Binding of Nos3 13 0.37 9.32 1.87 65.76
62 INT20421 Positive_regulation of MYC 19 0.67 10.43 1.9 61.76
63 INT9385 Localization of LDHA 74 0.81 31.67 10.5 57.88
64 INT82795 Binding of MYC 16 0.47 6.1 0.9 54.52
65 INT154147 Gene_expression of TP73 7 0.34 3.97 0.19 53.48
66 INT61949 Regulation of Nos2 74 0.58 34.08 16.7 53.12
67 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 52.32
68 INT55944 Positive_regulation of Cpox 214 0.57 105.14 81.4 50.20
69 INT53949 Positive_regulation of Gene_expression of Cpox 82 0.65 38.12 25.93 50.20
70 INT202628 Gene_expression of Wnt1 20 0.67 9.2 0.82 42.72
71 INT338915 Positive_regulation of Phosphorylation of PLCG1 1 0.13 0.06 0.12 42.48
72 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49 42.16
73 INT111803 Phosphorylation of PLCG1 2 0.17 0.14 0.21 41.68
74 INT86245 Positive_regulation of Bcl2l1 15 0.46 12.67 3.11 30.80
75 INT14447 Localization of F2 20 0.79 12.77 2.67 28.48
76 INT276411 Negative_regulation of Gene_expression of Imraq3 1 0.06 0.28 0 28.16
77 INT276410 Gene_expression of Imraq3 11 0.11 6.31 1.88 27.68
78 INT130057 Positive_regulation of CAV1 12 0.65 8.96 0.77 19.12
79 INT35975 Regulation of Cpox 109 0.39 57.88 49.69 17.32
80 INT1281 Negative_regulation of Maoa 203 0.59 22.47 91.66 8.20
81 INT121818 Binding of STAT3 25 0.47 11.16 3.67 7.60
82 INT280595 Positive_regulation of RNASEH1 1 0.08 0.06 0.07 5.88
83 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
84 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
85 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14 5.00
86 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
87 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
88 INT63934 Phosphorylation of Ephb1 377 0.82 150.52 188.66 5.00
89 INT1303 Negative_regulation of Npr1 278 0.55 35.1 156.78 5.00
90 INT4259 Positive_regulation of Npr1 262 0.70 49.37 123.11 5.00
91 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 5.00
92 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 5.00
93 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
94 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 5.00
95 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
96 INT19511 Localization of Il6 212 0.81 118.17 67.67 5.00
97 INT3950 Gene_expression of Ptger2 293 0.77 122.28 62.42 5.00
98 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72 5.00
99 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
100 INT48920 Negative_regulation of Ephb1 107 0.57 43.6 51.02 5.00
101 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 5.00
102 INT48929 Regulation of Ephb1 71 0.62 24.42 42.11 5.00
103 INT48924 Positive_regulation of Mapk3 107 0.67 50.53 34.05 5.00
104 INT109434 Phosphorylation of Mapk1 110 0.82 61.64 34.05 5.00
105 INT5989 Positive_regulation of Dbi 79 0.49 24.38 32.56 5.00
106 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 5.00
107 INT72375 Phosphorylation of Mapk3 87 0.80 43.66 30.27 5.00
108 INT22764 Localization of Ptger2 81 0.64 24.38 26.77 5.00
109 INT12681 Regulation of Trib3 76 0.53 23.92 26.58 5.00
110 INT8205 Negative_regulation of Nppa 77 0.59 26.43 25.72 5.00
111 INT71781 Phosphorylation of MAPK3 62 0.80 27.73 23.73 5.00
112 INT69322 Negative_regulation of MAPK14 70 0.54 42.92 22.71 5.00
113 INT11157 Binding of EGF 88 0.48 53.73 21.25 5.00
114 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78 5.00
115 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61 5.00
116 INT111401 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 134 0.61 34.87 20.15 5.00
117 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 5.00
118 INT12725 Positive_regulation of Racgap1 66 0.68 32.74 19.29 5.00
119 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 5.00
120 INT62826 Negative_regulation of Gene_expression of ICAM1 75 0.58 46.39 17.72 5.00
121 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 5.00
122 INT2480 Negative_regulation of Got1 43 0.51 14.47 16.09 5.00
123 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95 5.00
124 INT11762 Regulation of Dbi 40 0.62 7.83 14.48 5.00
125 INT35029 Positive_regulation of Gene_expression of Ptger2 66 0.43 26.37 13.99 5.00
126 INT53948 Regulation of Gene_expression of Cpox 40 0.51 20.97 13.87 5.00
127 INT3174 Negative_regulation of Ptger2 43 0.38 20.95 13.43 5.00
128 INT36287 Binding of CD4 96 0.47 58.93 11.88 5.00
129 INT72221 Localization of PRKCA 17 0.81 1.23 11.47 5.00
130 INT204112 Gene_expression of GEM 43 0.75 38.74 11.23 5.00
131 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09 5.00
132 INT8021 Gene_expression of Enpp1 43 0.78 31.46 10.8 5.00
133 INT15172 Positive_regulation of Itgam 45 0.67 23.54 10.3 5.00
134 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25 5.00
135 INT5512 Negative_regulation of Dbi 32 0.36 7.33 9.1 5.00
136 INT111133 Negative_regulation of Mapk3 31 0.57 10.89 8.9 5.00
137 INT44775 Gene_expression of ap 33 0.51 6.2 8.65 5.00
138 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27 5.00
139 INT45234 Binding of Ldha 20 0.37 9.8 8.18 5.00
140 INT156396 Localization of Tg(CAG-EGFP)D4Nagy 61 0.55 13.63 8.17 5.00
141 INT25953 Positive_regulation of Localization of Ptger2 29 0.42 5.91 8.1 5.00
142 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 5.00
143 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51 5.00
144 INT27170 Gene_expression of Maoa 13 0.67 3.88 7.5 5.00
145 INT96994 Phosphorylation of EGFR 99 0.82 52.75 7.33 5.00
146 INT6210 Binding of Nppa 39 0.47 14.35 7.21 5.00
147 INT83529 Positive_regulation of Positive_regulation of Cpox 8 0.29 7.22 6.7 5.00
148 INT34767 Gene_expression of PTGIR 36 0.42 14.79 6.69 5.00
149 INT11154 Binding of EGFR 149 0.48 96.23 6.29 5.00
150 INT135170 Positive_regulation of Hif1a 86 0.67 99.4 6.07 5.00
151 INT19779 Binding of Dbi 41 0.36 8.8 5.87 5.00
152 INT50704 Binding of Trib3 13 0.31 6.33 5.46 5.00
153 INT13396 Gene_expression of DMD 125 0.75 57.81 5.45 5.00
154 INT95696 Gene_expression of Dmd 130 0.68 26.02 5.34 5.00
155 INT60585 Regulation of TP53 59 0.59 54.55 5.21 5.00
156 INT97905 Positive_regulation of FGF2 33 0.70 26.74 5.17 5.00
157 INT174193 Gene_expression of LILRA3 20 0.28 12.65 5.1 5.00
158 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07 5.00
159 INT23045 Positive_regulation of Hbb 31 0.64 19.35 4.54 5.00
160 INT21990 Negative_regulation of Ctrc 17 0.42 8.45 4.47 5.00
161 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45 5.00
162 INT119203 Gene_expression of CXADR 64 0.74 11.37 4.41 5.00
163 INT51898 Binding of PECAM1 26 0.36 18.87 4.22 5.00
164 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68 5.00
165 INT93399 Gene_expression of Ccnd1 38 0.58 21 3.65 5.00
166 INT129751 Regulation of Phosphorylation of Mapk3 11 0.55 3.91 3.35 5.00
167 INT8103 Binding of TP53 46 0.44 40.2 2.96 5.00
168 INT184477 Negative_regulation of Pten 27 0.59 15.61 2.8 5.00
169 INT4419 Gene_expression of GOT1 20 0.65 22.53 2.53 5.00
170 INT69789 Binding of Fn1 13 0.36 5.08 2.18 5.00
171 INT21611 Negative_regulation of RASGRP1 20 0.35 11.76 2.15 5.00
172 INT201961 Positive_regulation of Gene_expression of ap 7 0.31 0.66 1.98 5.00
173 INT106636 Binding of PRKCA 7 0.28 3.06 1.93 5.00
174 INT101243 Regulation of STAT3 12 0.62 9.98 1.92 5.00
175 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87 5.00
176 INT96993 Positive_regulation of Phosphorylation of EGFR 15 0.59 5.44 1.37 5.00
177 INT190804 Positive_regulation of Tlr2 6 0.66 3.7 1.16 5.00
178 INT166171 Negative_regulation of Gene_expression of HRAS 5 0.07 3.98 1.11 5.00
179 INT71031 Gene_expression of ADRB1 5 0.55 2.96 1.01 5.00
180 INT190418 Positive_regulation of AAVS1 15 0.49 4.71 0.98 5.00
181 INT87734 Regulation of ARAF 4 0.23 2.44 0.76 5.00
182 INT90757 Gene_expression of Brp8 4 0.14 1.6 0.75 5.00
183 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75 5.00
184 INT50501 Negative_regulation of TBXAS1 3 0.30 1.26 0.74 5.00
185 INT70652 Negative_regulation of Binding of EGF 7 0.43 4.23 0.7 5.00
186 INT153667 Localization of CAV1 15 0.76 11.92 0.68 5.00
187 INT210390 Binding of PDGFA 12 0.36 6.78 0.63 5.00
188 INT131001 Regulation of CAV1 6 0.44 3.77 0.59 5.00
189 INT200754 Gene_expression of Rpe 35 0.51 6.3 0.58 5.00
190 INT16671 Gene_expression of MBTPS1 7 0.30 4.8 0.52 5.00
191 INT155033 Gene_expression of Phlda2 18 0.30 9.45 0.5 5.00
192 INT163114 Positive_regulation of Gene_expression of GOT1 7 0.24 8.93 0.5 5.00
193 INT276408 Positive_regulation of Gene_expression of Imraq3 2 0.07 1.26 0.49 5.00
194 INT171362 Gene_expression of Raf1 13 0.66 8.36 0.49 5.00
195 INT207493 Regulation of Gene_expression of ap 2 0.30 0.44 0.48 5.00
196 INT48445 Localization of Il3 3 0.11 0.14 0.48 5.00
197 INT252737 Gene_expression of RAF1 12 0.58 10.97 0.42 5.00
198 INT277727 Negative_regulation of Casp7 2 0.21 2.42 0.4 5.00
199 INT140896 Gene_expression of GPNMB 9 0.51 7.38 0.4 5.00
200 INT162049 Phosphorylation of F2 3 0.47 0.99 0.39 5.00
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