D:Babesiosis

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Disease Term
Synonyms Babesiases, BABESIASIS, Babesioses, Piroplasmoses, PIROPLASMOSIS
Documents 35
Hot Single Events 10
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Babesiosis. They are ordered first by their relevance to Babesiosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT308896 Binding of Babr and Lmrq1 1 0.01 1.24 0 96.32
2 INT218510 Binding of C3 and Cfb 1 0.02 0.53 0.2 10.36
3 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55 5.00
4 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98 5.00
5 INT198652 F2 Positive_regulation of Gene_expression of CD36 1 0.03 1.32 0.37 5.00
6 INT198647 TNF Positive_regulation of HIF1A 1 0.03 2.97 0.34 5.00
7 INT198642 GPI Positive_regulation of TNF 1 0.03 0.98 0.33 5.00
8 INT198640 TNF Positive_regulation of ISYNA1 1 0.04 1.07 0.29 5.00
9 INT310255 Tlr4 Positive_regulation of Gene_expression of Cd86 2 0.18 0.06 0.27 5.00
10 INT198648 VCAM1 Positive_regulation of CADM1 1 0.00 1.1 0.25 5.00
11 INT198644 TNF Positive_regulation of CADM1 1 0.02 1.07 0.24 5.00
12 INT198643 CD36 Positive_regulation of CADM1 1 0.01 1.07 0.24 5.00
13 INT198649 Binding of HIF1A and MIF 1 0.01 1.53 0.18 5.00
14 INT198638 GPI Positive_regulation of Gene_expression of TNF 1 0.03 1.44 0.15 5.00
15 INT347012 Hand2 Positive_regulation of Il4 1 0.01 0 0.14 5.00
16 INT347015 Hand2 Regulation of Cd86 1 0.06 0 0.14 5.00
17 INT347018 Cd80 Regulation of Hand2 1 0.03 0.05 0.13 5.00
18 INT218499 Cfb Negative_regulation of ap 1 0.00 0.74 0.13 5.00
19 INT347019 Cd80 Regulation of Hand1 1 0.01 0.05 0.13 5.00
20 INT347007 Cd86 Regulation of Hand2 1 0.06 0.05 0.13 5.00
21 INT347014 Cd86 Regulation of Hand1 1 0.02 0.05 0.13 5.00
22 INT347017 Cd86 Positive_regulation of Gene_expression of Il4 1 0.03 0 0.13 5.00
23 INT198671 HIF1A Regulation of Positive_regulation of Epo 1 0.00 1.37 0.13 5.00
24 INT347006 Tlr4 Positive_regulation of Cd86 1 0.17 0 0.09 5.00
25 INT218511 Cfb Positive_regulation of C5 1 0.01 0.29 0.06 5.00
26 INT218503 Cfb Positive_regulation of C3 1 0.01 0.29 0.06 5.00
27 INT347021 Cd86 Positive_regulation of Gene_expression of IGHE 1 0.03 0.18 0.05 5.00
28 INT347011 Negative_regulation of Mdk Negative_regulation of Regulation of Cd86 1 0.05 0 0.04 5.00
29 INT347016 Cd86 Regulation of Gene_expression of Il4 1 0.03 0.19 0.04 5.00
30 INT347020 Hand2 Regulation of Gene_expression of Cd86 1 0.08 0.19 0.04 5.00
31 INT198639 S100A12 Positive_regulation of TNF 1 0.15 1.49 0.04 5.00
32 INT198646 S100A12 Positive_regulation of IL1B 1 0.01 1.49 0.04 5.00
33 INT347009 Hand2 Regulation of Gene_expression of Il4 1 0.01 0.19 0.04 5.00
34 INT198651 Positive_regulation of S100A12 Positive_regulation of TNF 1 0.15 1.5 0.04 5.00
35 INT198650 Positive_regulation of S100A12 Positive_regulation of IL1B 1 0.01 1.5 0.04 5.00
36 INT347013 Il4 Regulation of Gene_expression of Cd86 1 0.02 0.07 0 5.00
37 INT218506 Binding of LCN1 and Cfb 1 0.04 0.25 0 5.00
38 INT218509 Binding of BCR and Cfb 1 0.00 0.18 0 5.00
39 INT218508 Negative_regulation of Binding of C3 and Cfb 1 0.01 0 0 5.00
40 INT218513 Binding of C3AR1 and ap 1 0.00 0.36 0 5.00
41 INT218505 Binding of C5 and Cfb 1 0.01 0.29 0 5.00
42 INT218514 BCR Negative_regulation of Binding of Cfb 1 0.00 0.18 0 5.00
43 INT218531 Binding of C6 and TCN2 1 0.00 0 0 5.00
44 INT218532 Binding of C5 and LCN1 1 0.06 0.49 0 5.00
45 INT218504 ap Regulation of CP 1 0.00 0.28 0 5.00
46 INT347008 Tlr4 Positive_regulation of Phosphorylation of Mapk14 1 0.02 0.06 0 5.00
47 INT218498 Binding of C4b and Daf2 1 0.04 0.26 0 5.00
48 INT218512 Binding of TCN2 and Cfb 1 0.00 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Babesiosis. They are ordered first by their pain relevance and then by number of times they were reported in Babesiosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT45234 Binding of Ldha 20 0.37 9.8 8.18 99.22
2 INT63673 Positive_regulation of Binding of Ldha 2 0.44 1.91 0.9 99.22
3 INT9552 Positive_regulation of TNNI3 209 0.70 128.67 19.15 98.16
4 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43 97.84
5 INT245871 Positive_regulation of Gene_expression of Babr 1 0.02 1.61 0 96.28
6 INT54616 Gene_expression of Babr 6 0.24 3.02 0.24 95.88
7 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 95.56
8 INT65889 Gene_expression of RETNLB 73 0.34 60.98 38.3 93.92
9 INT198682 Positive_regulation of Ifna 5 0.49 2.61 0.37 88.16
10 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 84.96
11 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 79.36
12 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 76.24
13 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 76.16
14 INT294152 Binding of Lmrq1 6 0.23 3.93 0 75.36
15 INT272794 Positive_regulation of Positive_regulation of IGHG3 3 0.04 2.84 0.17 75.32
16 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 73.48
17 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 72.56
18 INT191731 Gene_expression of Lmrq1 31 0.43 14.46 0.34 52.56
19 INT6852 Localization of TNF 883 0.81 705.95 270.84 50.72
20 INT216512 Gene_expression of C3AR1 13 0.70 8.44 1.31 36.48
21 INT3309 Binding of CP 25 0.47 17.87 6.62 23.92
22 INT9550 Gene_expression of TNNI3 113 0.78 86.79 10.56 20.40
23 INT85297 Positive_regulation of Gene_expression of TNNI3 29 0.50 29.77 1.68 20.40
24 INT9547 Regulation of TNNI3 25 0.56 14.22 2.22 14.40
25 INT4863 Positive_regulation of ap 22 0.37 9.13 6.11 13.28
26 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 12.88
27 INT116361 Positive_regulation of Protein_catabolism of C3 6 0.45 1.86 0.69 12.44
28 INT116360 Protein_catabolism of C3 19 0.64 4.4 1 11.92
29 INT29094 Binding of C3 39 0.37 12.65 2.27 10.36
30 INT184378 Binding of Cfb 54 0.20 12.49 2.36 10.00
31 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
32 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 5.00
33 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
34 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
35 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
36 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
37 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
38 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 5.00
39 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 5.00
40 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
41 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
42 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 5.00
43 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 5.00
44 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
45 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
46 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
47 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 5.00
48 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
49 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46 5.00
50 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 5.00
51 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 5.00
52 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 5.00
53 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 5.00
54 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 5.00
55 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 5.00
56 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
57 INT1536 Negative_regulation of NA 244 0.55 52.67 59.79 5.00
58 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
59 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32 5.00
60 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 5.00
61 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 5.00
62 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 5.00
63 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
64 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28 5.00
65 INT70437 Negative_regulation of Mdk 115 0.57 41.03 35.72 5.00
66 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 5.00
67 INT84825 Gene_expression of CD36 121 0.78 43.73 33.23 5.00
68 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 5.00
69 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 5.00
70 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75 5.00
71 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
72 INT21900 Gene_expression of Mthfd1 150 0.75 69.47 27.03 5.00
73 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
74 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95 5.00
75 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 5.00
76 INT134651 Binding of TLR4 89 0.48 66.96 23.19 5.00
77 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22 5.00
78 INT96156 Gene_expression of Cd40 144 0.77 56.95 21.7 5.00
79 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37 5.00
80 INT1756 Negative_regulation of DNAH8 105 0.59 42.73 20.24 5.00
81 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 5.00
82 INT756 Gene_expression of C3 138 0.75 100.6 19.2 5.00
83 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 5.00
84 INT73252 Positive_regulation of Mthfd1 124 0.59 59.48 18.35 5.00
85 INT112017 Regulation of Hand2 77 0.36 62.23 18.04 5.00
86 INT111531 Negative_regulation of Phosphorylation of Mapk14 37 0.50 20 17.68 5.00
87 INT96155 Gene_expression of Cd86 134 0.77 50.56 17.13 5.00
88 INT6850 Gene_expression of SPANXB1 34 0.46 15.91 16.38 5.00
89 INT104045 Regulation of Hand1 65 0.35 51.32 16.26 5.00
90 INT98647 Positive_regulation of Mdk 65 0.59 32.93 15.67 5.00
91 INT111462 Negative_regulation of Phosphorylation of Mapk1 45 0.57 19.49 15.59 5.00
92 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8 5.00
93 INT2385 Gene_expression of MIF 57 0.68 40.74 12.78 5.00
94 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63 5.00
95 INT4137 Positive_regulation of C3 73 0.69 48.57 12.63 5.00
96 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 5.00
97 INT39587 Gene_expression of CP 42 0.65 31.48 11.87 5.00
98 INT111223 Positive_regulation of HMOX1 47 0.70 39.14 10.92 5.00
99 INT4498 Gene_expression of F2 83 0.65 57.4 10.8 5.00
100 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4 5.00
101 INT55418 Regulation of CYP2D6 29 0.61 1.83 10.21 5.00
102 INT96157 Gene_expression of Cd80 74 0.77 31.19 9.78 5.00
103 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 5.00
104 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17 5.00
105 INT44775 Gene_expression of ap 33 0.51 6.2 8.65 5.00
106 INT79693 Regulation of Il4 30 0.51 21.96 8.6 5.00
107 INT102658 Negative_regulation of Gene_expression of CSF2 42 0.50 38.63 8.32 5.00
108 INT573 Negative_regulation of C3 60 0.59 41.37 7.78 5.00
109 INT75841 Binding of Trav6-3 66 0.47 29.14 7.63 5.00
110 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41 5.00
111 INT93046 Positive_regulation of Gene_expression of Hand2 27 0.47 24.54 7.01 5.00
112 INT125143 Gene_expression of EPHB2 40 0.71 13.27 6.97 5.00
113 INT142082 Positive_regulation of IDO1 17 0.60 9.46 6.33 5.00
114 INT121370 Positive_regulation of MIF 22 0.70 17.79 6.08 5.00
115 INT142607 Positive_regulation of Gene_expression of Cd40 41 0.62 13.85 5.51 5.00
116 INT45753 Localization of CD40LG 45 0.79 32.31 5.28 5.00
117 INT62525 Positive_regulation of SELE 38 0.70 46 5.25 5.00
118 INT83442 Negative_regulation of MIF 18 0.57 9.51 5.12 5.00
119 INT191343 Gene_expression of IDO1 23 0.55 11.3 4.81 5.00
120 INT55419 Regulation of CYP1A2 19 0.62 5.3 4.75 5.00
121 INT135990 Positive_regulation of Gene_expression of Cd86 34 0.69 12.02 4.53 5.00
122 INT108342 Negative_regulation of EPHB2 18 0.57 9.48 4.46 5.00
123 INT9842 Binding of F2 36 0.47 22.79 4.42 5.00
124 INT504 Gene_expression of GPT 42 0.75 27.54 3.99 5.00
125 INT43931 Binding of CFH 49 0.48 31.85 3.96 5.00
126 INT6507 Binding of C5 23 0.48 15.35 3.91 5.00
127 INT184288 Localization of HMGB1 20 0.61 14.5 3.84 5.00
128 INT47372 Regulation of ap 12 0.18 2.14 3.76 5.00
129 INT107074 Gene_expression of C5 14 0.75 9.87 3.64 5.00
130 INT25356 Positive_regulation of S100A12 18 0.69 17.62 3.38 5.00
131 INT188355 Binding of Cd28 25 0.34 8.29 3.38 5.00
132 INT85260 Negative_regulation of ATF7IP 14 0.41 7.08 3.17 5.00
133 INT163290 Binding of MIF 9 0.31 7.57 2.8 5.00
134 INT41874 Positive_regulation of GPI 9 0.49 9.97 2.79 5.00
135 INT64147 Gene_expression of C5 15 0.60 16.8 2.78 5.00
136 INT71933 Positive_regulation of Gene_expression of F2 19 0.56 14.24 2.53 5.00
137 INT39560 Positive_regulation of F10 25 0.67 10.67 2.5 5.00
138 INT198662 Positive_regulation of CD36 14 0.68 7.73 2.36 5.00
139 INT96154 Negative_regulation of Gene_expression of Cd86 10 0.48 3.76 2.35 5.00
140 INT76226 Binding of SPANXB1 6 0.24 1.16 2.23 5.00
141 INT103095 Binding of ISYNA1 10 0.28 6.17 2.03 5.00
142 INT45004 Gene_expression of Cfb 28 0.37 15.06 1.99 5.00
143 INT35689 Localization of C3 17 0.75 5.3 1.98 5.00
144 INT15580 Gene_expression of TCN2 16 0.44 7.59 1.97 5.00
145 INT47371 Negative_regulation of ap 32 0.32 9.8 1.96 5.00
146 INT129240 Positive_regulation of Stat6 6 0.67 1.96 1.92 5.00
147 INT16385 Regulation of C3 20 0.41 9.98 1.92 5.00
148 INT15742 Negative_regulation of EPO 37 0.59 17.44 1.84 5.00
149 INT64538 Binding of TNNI3 17 0.48 11.65 1.83 5.00
150 INT130775 Regulation of FASLG 4 0.30 5.8 1.82 5.00
151 INT228401 Positive_regulation of Cd86 24 0.53 6.46 1.8 5.00
152 INT98580 Positive_regulation of CADM1 11 0.49 10.16 1.78 5.00
153 INT191862 Phosphorylation of Tlr4 17 0.79 6.89 1.74 5.00
154 INT135991 Positive_regulation of Gene_expression of Cd80 19 0.54 6.9 1.71 5.00
155 INT565 Negative_regulation of Cfb 18 0.13 6.77 1.69 5.00
156 INT3818 Regulation of Apc 13 0.39 12.52 1.68 5.00
157 INT198663 Positive_regulation of HMGB1 14 0.52 11.41 1.58 5.00
158 INT48412 Gene_expression of Apcs 26 0.54 7.16 1.53 5.00
159 INT237377 Regulation of Gene_expression of Cd86 10 0.47 3.64 1.52 5.00
160 INT46389 Positive_regulation of Cfb 20 0.23 8.29 1.49 5.00
161 INT303913 Regulation of Regulation of CYP2D6 2 0.37 1.09 1.48 5.00
162 INT292298 Positive_regulation of GOT2 5 0.45 3.7 1.46 5.00
163 INT60552 Localization of TNNI3 56 0.79 20.05 1.44 5.00
164 INT58034 Positive_regulation of TCN2 8 0.04 2.11 1.43 5.00
165 INT25621 Localization of Cfb 8 0.20 2.23 1.4 5.00
166 INT117014 Binding of TCN2 11 0.13 1.6 1.38 5.00
167 INT75183 Negative_regulation of TNNI3 19 0.53 9.34 1.32 5.00
168 INT181526 Positive_regulation of Apcs 13 0.49 4.09 1.3 5.00
169 INT204772 Negative_regulation of Gene_expression of Mthfd1 10 0.15 3.48 1.29 5.00
170 INT223121 Positive_regulation of Positive_regulation of Mdk 6 0.20 2.7 1.27 5.00
171 INT11203 Gene_expression of BCR 30 0.75 33.49 1.22 5.00
172 INT115214 Gene_expression of LSAMP 4 0.63 2.5 1.14 5.00
173 INT189836 Regulation of Cd40 10 0.40 3.02 1.1 5.00
174 INT165275 Regulation of Cfb 5 0.06 0.83 1.06 5.00
175 INT102249 Binding of HIF1A 39 0.36 30.47 1.04 5.00
176 INT50878 Positive_regulation of Positive_regulation of TNNI3 7 0.50 5.57 0.97 5.00
177 INT178026 Positive_regulation of Epo 12 0.70 8.14 0.95 5.00
178 INT58868 Positive_regulation of Negative_regulation of ap 3 0.35 0 0.86 5.00
179 INT28689 Negative_regulation of Positive_regulation of C3 4 0.23 1.28 0.85 5.00
180 INT67038 Positive_regulation of Positive_regulation of ALPP 5 0.08 2.61 0.77 5.00
181 INT198669 Binding of THBD 5 0.10 4.45 0.75 5.00
182 INT27077 Binding of CD36 4 0.37 2.14 0.72 5.00
183 INT168000 Protein_catabolism of F2 6 0.63 2.19 0.63 5.00
184 INT166437 Binding of C5 4 0.36 3.28 0.63 5.00
185 INT302544 Regulation of Cd86 10 0.34 1.89 0.62 5.00
186 INT38720 Protein_catabolism of C3AR1 2 0.17 0.18 0.62 5.00
187 INT122737 Gene_expression of Daf2 6 0.69 2.11 0.61 5.00
188 INT207497 Binding of ap 4 0.14 0.53 0.57 5.00
189 INT183164 Regulation of Cd80 6 0.33 2.69 0.52 5.00
190 INT85081 Protein_catabolism of C5 5 0.19 1.34 0.5 5.00
191 INT218445 Gene_expression of Smarcb1 3 0.75 2.21 0.45 5.00
192 INT129477 Localization of ATF7IP 4 0.73 1.22 0.39 5.00
193 INT207775 Negative_regulation of Gene_expression of C5 4 0.42 2.08 0.33 5.00
194 INT92313 Negative_regulation of Gene_expression of TNNI3 3 0.41 3.07 0.28 5.00
195 INT218463 Negative_regulation of Binding of Cfb 7 0.08 2.31 0.28 5.00
196 INT184346 Positive_regulation of Binding of Cfb 2 0.10 0.83 0.28 5.00
197 INT198666 Regulation of Gene_expression of IDO1 1 0.05 1.77 0.26 5.00
198 INT331559 Positive_regulation of Positive_regulation of Apcs 1 0.21 0.8 0.22 5.00
199 INT198659 Protein_catabolism of F10 1 0.01 0.51 0.22 5.00
200 INT303912 Negative_regulation of Localization of ATF7IP 1 0.21 0.16 0.22 5.00
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