D:Babinski Reflex

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Disease Term
Synonyms Babinski Reflexes, Babinski S Reflex, Babinski S Sign, BABINSKI S SIGNS, BABINSKI SIGN, BABINSKI SIGN ABSENT, Babinski Sign Negative, Babinski Sign Positive, BABINSKI SIGNS, Extensor Plantar Reflex, EXTENSOR PLANTAR RESPONSE
Documents 125
Hot Single Events 15
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Babinski Reflex. They are ordered first by their relevance to Babinski Reflex and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93 5.00
2 INT336946 Binding of ITGA4 and VCAM1 1 0.03 2.02 0.21 5.00
3 INT302712 Binding of Hprt and Hrh1 1 0.25 1.07 0.2 5.00
4 INT302711 Binding of Hrh1 and Spnb4 1 0.18 1.07 0.2 5.00
5 INT259023 CADPS Positive_regulation of Binding of SH2B2 1 0.06 2.05 0.14 5.00
6 INT199667 Cep290 Regulation of Atf4 1 0.04 1.96 0.09 5.00
7 INT199666 Cntln Regulation of Atf4 1 0.00 1.95 0.09 5.00
8 INT332588 Binding of RAPH1 and MND1 1 0.01 3.88 0.07 5.00
9 INT199665 Binding of Fxn and Lamtor3 1 0.00 0.16 0.03 5.00
10 INT332587 MND1 Positive_regulation of Binding of RAPH1 and MND1 1 0.00 2.21 0.03 5.00
11 INT192678 PTEN Regulation of Dync1h1 1 0.02 0.5 0.03 5.00
12 INT239406 Binding of MTTP and TAOK1 1 0.02 0.51 0 5.00
13 INT239407 Binding of MTTP and PADI1 1 0.23 0.5 0 5.00
14 INT239408 Binding of PADI1 and TAOK1 1 0.01 0.51 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Babinski Reflex. They are ordered first by their pain relevance and then by number of times they were reported in Babinski Reflex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT10847 Gene_expression of LAMC2 39 0.75 27 12.09 98.84
2 INT63814 Gene_expression of NKG7 3 0.58 2.76 0.54 98.68
3 INT4437 Positive_regulation of ABCB7 11 0.68 11.26 1.33 97.16
4 INT1867 Positive_regulation of GABBR1 6 0.69 0.55 1.18 94.48
5 INT205596 Negative_regulation of COQ10A 22 0.51 15.61 2.77 91.64
6 INT100746 Localization of sar 2 0.62 13.88 2.61 89.64
7 INT81328 Gene_expression of sar 7 0.66 2.86 1.85 89.64
8 INT64824 Negative_regulation of sar 11 0.42 18.7 5.6 86.20
9 INT199649 Gene_expression of Fxn 12 0.72 20.9 0.74 86.16
10 INT205594 Gene_expression of COQ10A 19 0.67 12.53 2.56 85.72
11 INT309255 Gene_expression of NDUFV1 1 0.01 2.33 0 83.12
12 INT132335 Gene_expression of KCNA1 36 0.77 18.31 13.36 82.12
13 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 82.08
14 INT102187 Gene_expression of SH2B2 23 0.59 26.54 4.39 81.84
15 INT115300 Negative_regulation of Napa 7 0.23 1 2.68 80.24
16 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 77.44
17 INT199641 Regulation of Transcription of Fxn 1 0.29 1.89 0.04 77.04
18 INT199648 Regulation of Fxn 1 0.29 2.14 0.04 77.04
19 INT331605 Negative_regulation of Localization of sar 1 0.35 0.88 0.13 76.48
20 INT199646 Transcription of Fxn 2 0.67 4.78 0.08 76.36
21 INT88464 Negative_regulation of CST7 11 0.31 5.33 2.17 74.08
22 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36 72.16
23 INT103716 Gene_expression of Cms1 14 0.65 8.52 1.3 70.88
24 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 69.52
25 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 67.92
26 INT25 Positive_regulation of LAMC2 19 0.67 8.64 7.06 64.60
27 INT149380 Localization of Cish 3 0.64 3.44 1.06 63.96
28 INT756 Gene_expression of C3 138 0.75 100.6 19.2 62.24
29 INT35584 Binding of ACLY 22 0.35 31.78 7.17 55.52
30 INT309245 Binding of SETX 1 0.08 1.98 0.06 54.08
31 INT3496 Negative_regulation of HPRT1 7 0.58 25.05 1.92 53.60
32 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 49.36
33 INT175556 Regulation of Positive_regulation of PTH 3 0.39 2.34 0.12 49.36
34 INT131674 Negative_regulation of HEXB 3 0.10 3.78 0.32 48.72
35 INT239412 Binding of ABL1 8 0.28 5.39 0.18 42.68
36 INT236839 Positive_regulation of CXCL13 14 0.44 19.27 5.81 36.68
37 INT182240 Gene_expression of CXCL13 25 0.59 22.77 11.96 32.32
38 INT236842 Positive_regulation of Gene_expression of CXCL13 6 0.32 3.91 2.55 32.32
39 INT87988 Gene_expression of ASAH1 9 0.77 9.75 1.18 30.96
40 INT229301 Gene_expression of NR0B2 3 0.18 3.49 0.16 30.64
41 INT240280 Gene_expression of IGFALS 14 0.42 20.38 0.95 30.44
42 INT182215 Regulation of CXCR5 4 0.27 4.49 2.18 30.08
43 INT6512 Gene_expression of PTH 103 0.77 76.29 6.33 28.60
44 INT266786 Binding of ASAH1 2 0.11 3.87 0.44 24.16
45 INT36479 Binding of NR0B2 2 0.36 3.5 0.21 24.16
46 INT332592 Binding of MND1 1 0.08 9.21 0.16 22.64
47 INT3911 Gene_expression of TNFAIP1 29 0.65 21.68 1.85 21.48
48 INT67048 Gene_expression of ITGA4 58 0.75 28.93 10.16 13.44
49 INT12861 Gene_expression of Cish 40 0.57 23.01 8.48 6.40
50 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 5.12
51 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
52 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 5.00
53 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 5.00
54 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98 5.00
55 INT2910 Regulation of Abat 169 0.62 36.95 153.53 5.00
56 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
57 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 5.00
58 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 5.00
59 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
60 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 5.00
61 INT74389 Gene_expression of Gdnf 131 0.78 58.52 57.06 5.00
62 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
63 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 5.00
64 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63 5.00
65 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 5.00
66 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
67 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
68 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4 5.00
69 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
70 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
71 INT5653 Positive_regulation of ELANE 136 0.70 72.78 27.94 5.00
72 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 5.00
73 INT134651 Binding of TLR4 89 0.48 66.96 23.19 5.00
74 INT8580 Gene_expression of ELANE 132 0.75 62.98 21.79 5.00
75 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
76 INT31874 Negative_regulation of Gene_expression of Abat 31 0.42 12.22 20.31 5.00
77 INT78024 Gene_expression of ACLY 73 0.75 59.15 18.54 5.00
78 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 5.00
79 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9 5.00
80 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93 5.00
81 INT71634 Gene_expression of SLC6A3 45 0.78 13.48 15.23 5.00
82 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89 5.00
83 INT60197 Gene_expression of JUN 90 0.78 42.32 14.61 5.00
84 INT65697 Positive_regulation of GRIN3B 23 0.69 12.52 13.78 5.00
85 INT69435 Negative_regulation of ROS1 74 0.51 50.38 13.71 5.00
86 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68 5.00
87 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 5.00
88 INT49975 Binding of SLC6A3 34 0.47 9.86 12.41 5.00
89 INT73829 Positive_regulation of Gene_expression of VCAM1 41 0.61 35.96 11.92 5.00
90 INT24816 Binding of CD40LG 68 0.47 45.48 11.56 5.00
91 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 5.00
92 INT4498 Gene_expression of F2 83 0.65 57.4 10.8 5.00
93 INT16449 Binding of IGHG3 67 0.48 39.55 10.59 5.00
94 INT123701 Negative_regulation of VDR 61 0.59 48.94 9.67 5.00
95 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 5.00
96 INT158796 Positive_regulation of SMUG1 67 0.70 38.97 8.98 5.00
97 INT36449 Negative_regulation of G6PD 74 0.59 54.15 8.85 5.00
98 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57 5.00
99 INT177831 Gene_expression of HDAC1 24 0.65 21.37 8.37 5.00
100 INT95414 Positive_regulation of Alms1 40 0.41 20.3 8.1 5.00
101 INT162393 Gene_expression of SMUG1 58 0.75 38.78 7.7 5.00
102 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51 5.00
103 INT10478 Protein_catabolism of Alms1 25 0.47 12.95 7.19 5.00
104 INT11957 Negative_regulation of LPA 52 0.59 39.09 6.84 5.00
105 INT49212 Negative_regulation of GAD1 23 0.59 22.15 6.54 5.00
106 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 5.00
107 INT57232 Binding of Casp3 22 0.36 9.42 6.2 5.00
108 INT53184 Negative_regulation of CYP27A1 46 0.57 16.04 5.28 5.00
109 INT45753 Localization of CD40LG 45 0.79 32.31 5.28 5.00
110 INT10100 Binding of ELANE 22 0.47 15.32 5.19 5.00
111 INT140350 Binding of C2 17 0.36 3.97 4.69 5.00
112 INT190833 Regulation of KCNA1 8 0.53 6.61 4.66 5.00
113 INT51030 Negative_regulation of LMOD1 9 0.44 5.83 4.58 5.00
114 INT36309 Negative_regulation of DIO2 18 0.57 6.42 4.51 5.00
115 INT32933 Gene_expression of GNAS 57 0.32 10.58 4.03 5.00
116 INT3405 Gene_expression of BCAR1 14 0.71 8.89 4.02 5.00
117 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95 5.00
118 INT184288 Localization of HMGB1 20 0.61 14.5 3.84 5.00
119 INT33008 Gene_expression of Dync1h1 41 0.68 23.85 3.82 5.00
120 INT1727 Gene_expression of Cndp2 22 0.74 4.28 3.34 5.00
121 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32 5.00
122 INT3403 Positive_regulation of BCAR1 18 0.63 18.95 3.23 5.00
123 INT81453 Positive_regulation of Gene_expression of JUN 18 0.50 9.39 3.23 5.00
124 INT175262 Binding of SH2B2 18 0.36 22.85 3.18 5.00
125 INT25906 Negative_regulation of Cish 6 0.29 5.41 3.17 5.00
126 INT77670 Positive_regulation of ACLY 24 0.49 21.68 3.12 5.00
127 INT25674 Positive_regulation of Gene_expression of ELANE 16 0.60 7.46 3.12 5.00
128 INT192676 Binding of PTEN 14 0.46 10.58 3.06 5.00
129 INT43907 Binding of CD79A 28 0.48 28.11 3.04 5.00
130 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04 5.00
131 INT87314 Gene_expression of Htt 112 0.78 55.82 3.03 5.00
132 INT61791 Positive_regulation of SH2B2 9 0.50 8.36 2.99 5.00
133 INT45971 Negative_regulation of GOT1 9 0.51 6.2 2.84 5.00
134 INT143551 Binding of KCNA1 13 0.46 8.81 2.81 5.00
135 INT65642 Binding of Dync1h1 27 0.41 15.83 2.68 5.00
136 INT50080 Binding of APOE 38 0.45 29.61 2.67 5.00
137 INT18848 Localization of LMOD1 5 0.69 1 2.49 5.00
138 INT204019 Negative_regulation of C2 10 0.26 6.23 2.44 5.00
139 INT74446 Positive_regulation of Dync1h1 25 0.59 13 2.38 5.00
140 INT161575 Localization of CACNA1A 4 0.75 5.28 2.26 5.00
141 INT209501 Gene_expression of CADPS 15 0.65 20.7 2.22 5.00
142 INT56658 Gene_expression of Spnb4 7 0.58 5.6 2.22 5.00
143 INT19804 Negative_regulation of Hprt 18 0.59 20.6 2.17 5.00
144 INT39453 Negative_regulation of TCN2 12 0.59 3.98 2.13 5.00
145 INT29393 Positive_regulation of APRT 18 0.67 5.28 2.13 5.00
146 INT11183 Negative_regulation of SH2B2 4 0.34 6.99 2.12 5.00
147 INT9749 Positive_regulation of sar 25 0.50 9.96 2.09 5.00
148 INT15580 Gene_expression of TCN2 16 0.44 7.59 1.97 5.00
149 INT173512 Positive_regulation of Gene_expression of Alms1 12 0.44 8.66 1.95 5.00
150 INT56656 Positive_regulation of Spnb4 3 0.49 1.09 1.92 5.00
151 INT128030 Gene_expression of GJA1 23 0.75 7.81 1.88 5.00
152 INT40877 Positive_regulation of APOB 35 0.68 32.47 1.86 5.00
153 INT122895 Transcription of DIO2 3 0.52 0.91 1.73 5.00
154 INT97062 Binding of PML 10 0.41 11.63 1.65 5.00
155 INT88726 Gene_expression of HPRT1 36 0.78 10.12 1.58 5.00
156 INT309257 Transcription of LMOD1 3 0.36 1.71 1.57 5.00
157 INT9466 Binding of APOB 27 0.41 19.36 1.56 5.00
158 INT144380 Gene_expression of SYNE1 12 0.58 6.99 1.55 5.00
159 INT192673 Gene_expression of Hdac5 6 0.61 2.84 1.51 5.00
160 INT12035 Regulation of F2 21 0.45 12.66 1.47 5.00
161 INT259036 Transcription of SH2B2 2 0.55 7.01 1.46 5.00
162 INT181868 Localization of ACLY 5 0.62 6.36 1.4 5.00
163 INT105569 Binding of IGFALS 13 0.25 17.31 1.36 5.00
164 INT3404 Binding of BCAR1 10 0.33 7.97 1.33 5.00
165 INT61999 Gene_expression of MAPT 19 0.75 15.4 1.3 5.00
166 INT236277 Positive_regulation of Gene_expression of CADPS 5 0.42 9.17 1.29 5.00
167 INT74443 Positive_regulation of PML 11 0.53 12.52 1.21 5.00
168 INT123877 Negative_regulation of ABL1 40 0.57 27.94 1.17 5.00
169 INT132334 Negative_regulation of Gene_expression of KCNA1 4 0.43 1.52 1.14 5.00
170 INT192675 Positive_regulation of Gene_expression of Hdac5 2 0.33 2.52 1.13 5.00
171 INT209503 Positive_regulation of CADPS 3 0.42 7 1.11 5.00
172 INT22095 Negative_regulation of Dync1h1 11 0.48 5.17 1.08 5.00
173 INT67156 Binding of ITGA4 6 0.14 2.63 1.03 5.00
174 INT19803 Gene_expression of Hprt 15 0.67 4.81 1.03 5.00
175 INT235929 Regulation of Positive_regulation of Alms1 2 0.02 2.84 1.02 5.00
176 INT76057 Regulation of sar 9 0.23 2.05 0.96 5.00
177 INT85624 Gene_expression of GJB1 5 0.78 3.03 0.93 5.00
178 INT54296 Regulation of Spnb4 3 0.44 2.06 0.89 5.00
179 INT94563 Gene_expression of H2-Q10 7 0.42 7 0.88 5.00
180 INT11198 Negative_regulation of Gclc 3 0.59 0.49 0.87 5.00
181 INT50687 Gene_expression of Aldoc 6 0.78 0.17 0.78 5.00
182 INT22118 Negative_regulation of Cms1 6 0.38 4.02 0.78 5.00
183 INT57008 Positive_regulation of HPRT1 11 0.50 2.81 0.74 5.00
184 INT150165 Gene_expression of MTTP 21 0.75 10.1 0.73 5.00
185 INT160799 Regulation of IGFALS 11 0.29 9.09 0.7 5.00
186 INT230410 Negative_regulation of Gene_expression of TNFAIP1 3 0.16 3.67 0.63 5.00
187 INT649 Positive_regulation of Afp 10 0.55 6.5 0.62 5.00
188 INT309253 Negative_regulation of Transcription of LMOD1 1 0.03 0.2 0.57 5.00
189 INT194794 Binding of TTPA 7 0.08 2.56 0.57 5.00
190 INT240281 Positive_regulation of IGFALS 11 0.31 10.44 0.56 5.00
191 INT189813 Negative_regulation of CACNA1A 4 0.57 3.07 0.55 5.00
192 INT52740 Binding of ACLS 5 0.31 3 0.54 5.00
193 INT118716 Positive_regulation of MAPT 4 0.49 7.25 0.54 5.00
194 INT181325 Positive_regulation of TNFAIP1 4 0.36 4.64 0.52 5.00
195 INT73731 Binding of RAPH1 9 0.33 14.58 0.5 5.00
196 INT82177 Negative_regulation of H2-Q10 5 0.58 5.83 0.45 5.00
197 INT264689 Negative_regulation of IGFALS 10 0.33 12.58 0.45 5.00
198 INT309242 Localization of Nat1 1 0.01 0.17 0.42 5.00
199 INT259035 Localization of SH2B2 3 0.43 1.77 0.42 5.00
200 INT117662 Gene_expression of ABL1 21 0.69 18.76 0.39 5.00
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