D:Bacterial Endocarditis

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Disease Term
Synonyms Bacterial Endocarditides, Be Bacterial Endocarditis, Endocarditides Bacterial, ENDOCARDITIS BACTERIAL, Ie Infective Endocarditis, Infective Endocarditis
Documents 416
Hot Single Events 22
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Bacterial Endocarditis. They are ordered first by their relevance to Bacterial Endocarditis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT208461 Binding of CD4 and IL16 1 0.05 3.04 0.41 5.00
2 INT342457 CSF1 Negative_regulation of Gene_expression of CCR4 1 0.00 0.93 0.31 5.00
3 INT342458 CSF1 Positive_regulation of Gene_expression of CCL2 1 0.17 0.84 0.27 5.00
4 INT342456 AGT Positive_regulation of Gene_expression of CCL2 1 0.07 0.63 0.25 5.00
5 INT342459 CXCR3 Positive_regulation of CRTC1 1 0.00 0.59 0.11 5.00
6 INT223088 Binding of ELF3 and NAGLU 1 0.14 0.84 0.09 5.00
7 INT223089 Binding of IDS and NAGLU 1 0.26 0.72 0.09 5.00
8 INT296893 Nps Negative_regulation of Gene_expression of REN 1 0.00 1.05 0.04 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Bacterial Endocarditis. They are ordered first by their pain relevance and then by number of times they were reported in Bacterial Endocarditis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT253337 Localization of MT1E 4 0.59 8.89 0.41 100.00
2 INT251459 Binding of Ie 18 0.20 6.62 0.75 100.00
3 INT192070 Positive_regulation of Localization of Acly 1 0.02 0.84 0 99.46
4 INT159661 Binding of AHA 1 0.40 0.61 0 99.20
5 INT192069 Localization of Acly 1 0.02 0.84 0 99.18
6 INT27628 Gene_expression of IL2RG 28 0.75 20.95 6.16 98.20
7 INT208469 Positive_regulation of Positive_regulation of IL16 1 0.48 1.48 0.13 97.66
8 INT208467 Positive_regulation of IL16 31 0.67 40.09 2.56 97.46
9 INT35028 Positive_regulation of IL2RG 14 0.47 10.05 4.36 96.52
10 INT36052 Positive_regulation of Gene_expression of IL2RG 7 0.28 4.72 2.32 96.52
11 INT9973 Binding of MMVP1 14 0.48 22.66 1.79 94.72
12 INT62950 Gene_expression of NPPB 73 0.75 65.91 6.54 94.40
13 INT84811 Gene_expression of Ado 6 0.51 2.65 2.74 94.08
14 INT93789 Gene_expression of Tnnc1 28 0.76 17.3 1.99 93.84
15 INT13607 Binding of Ack 11 0.36 5.77 6.01 93.00
16 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 92.12
17 INT35460 Gene_expression of IL16 45 0.75 48.71 10.5 90.48
18 INT5788 Gene_expression of IL2RA 60 0.75 40.67 9.98 87.20
19 INT208465 Regulation of IL16 1 0.26 1.24 0.11 84.04
20 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 82.92
21 INT5789 Gene_expression of PMEL 23 0.75 13.18 2.67 82.76
22 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 80.72
23 INT131788 Positive_regulation of NPPB 87 0.67 86.1 8.81 78.12
24 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 75.84
25 INT100861 Binding of CRP 179 0.48 175.2 26.45 71.04
26 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33 61.92
27 INT81495 Positive_regulation of CNR2 28 0.67 14.62 14.27 61.92
28 INT35461 Positive_regulation of Gene_expression of IL16 22 0.67 25.57 4.24 60.16
29 INT9084 Positive_regulation of Nppb 74 0.70 69.77 11.85 53.04
30 INT102738 Binding of Atp9b 4 0.36 1.65 0.68 52.80
31 INT342455 Binding of Rnf130 1 0.36 0.73 0.16 52.48
32 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 50.00
33 INT15610 Localization of GOPC 223 0.65 68.26 28.7 50.00
34 INT255432 Binding of SAG 3 0.35 1.41 0.16 50.00
35 INT132419 Positive_regulation of ANXA5 9 0.59 5.22 2.38 49.96
36 INT117754 Gene_expression of NHS 34 0.57 9.27 3.28 48.88
37 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 39.68
38 INT35462 Negative_regulation of Gene_expression of IL16 9 0.53 2.04 6.83 35.20
39 INT78592 Positive_regulation of Atp9b 4 0.49 1.54 0.44 34.40
40 INT342454 Positive_regulation of Rnf130 1 0.49 0.61 0.05 34.00
41 INT107294 Positive_regulation of Cdt1 3 0.24 1.52 0.43 26.96
42 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 14.36
43 INT44955 Negative_regulation of Eln 8 0.42 3.79 0.83 11.88
44 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 5.00
45 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
46 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 5.00
47 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 5.00
48 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 5.00
49 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 5.00
50 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74 5.00
51 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
52 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 5.00
53 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22 5.00
54 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.00
55 INT65245 Gene_expression of Nos3 121 0.78 98.14 41.56 5.00
56 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38 5.00
57 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
58 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 5.00
59 INT104392 Gene_expression of Cxcl10 113 0.75 106.86 34.12 5.00
60 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 5.00
61 INT65698 Localization of CCL2 118 0.81 77.54 32.69 5.00
62 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4 5.00
63 INT121663 Gene_expression of CXCR3 76 0.77 50.96 30.62 5.00
64 INT67610 Positive_regulation of Pparg 53 0.70 31.91 25.2 5.00
65 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 5.00
66 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19 5.00
67 INT4781 Gene_expression of TH 68 0.73 26.92 24.01 5.00
68 INT94335 Positive_regulation of CXCL10 71 0.58 50.69 23 5.00
69 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 5.00
70 INT125312 Positive_regulation of COPD 134 0.59 162.55 20.27 5.00
71 INT192409 Positive_regulation of Gene_expression of IFN1@ 102 0.67 64.66 18.8 5.00
72 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 5.00
73 INT27670 Negative_regulation of Ace 122 0.57 79.21 18.08 5.00
74 INT80755 Gene_expression of CD40 88 0.75 53.68 17.86 5.00
75 INT10834 Binding of IL8 65 0.48 41.66 16.53 5.00
76 INT108588 Gene_expression of CASP3 126 0.78 84.49 16.2 5.00
77 INT75540 Positive_regulation of TH1L 62 0.67 43.45 15.02 5.00
78 INT180497 Binding of MRI1 45 0.42 28.35 14.77 5.00
79 INT54763 Binding of Il6 82 0.48 63.27 12.89 5.00
80 INT10585 Localization of NAGLU 53 0.80 23.32 12.75 5.00
81 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 5.00
82 INT159127 Gene_expression of Nps 49 0.75 16.91 12.06 5.00
83 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 5.00
84 INT661 Gene_expression of REN 100 0.78 48.21 11.36 5.00
85 INT94438 Gene_expression of OLR1 86 0.78 80.38 11.03 5.00
86 INT1934 Positive_regulation of Cys1 68 0.68 60.56 10.47 5.00
87 INT170333 Binding of IFN1@ 68 0.47 49.01 9.72 5.00
88 INT132586 Negative_regulation of Hand2 40 0.30 26.58 9.28 5.00
89 INT49802 Localization of MUC1 75 0.81 44.74 8.87 5.00
90 INT12095 Negative_regulation of Edn1 26 0.59 12.01 8.79 5.00
91 INT22383 Binding of IL2 59 0.48 39.06 8.56 5.00
92 INT86705 Gene_expression of BTG3 41 0.65 37.29 8.29 5.00
93 INT32454 Gene_expression of Ptafr 3 0.65 15.19 7.87 5.00
94 INT172789 Regulation of Gene_expression of Nos3 15 0.53 16.23 7.86 5.00
95 INT162393 Gene_expression of SMUG1 58 0.75 38.78 7.7 5.00
96 INT4228 Gene_expression of CAT 50 0.75 20.62 7.18 5.00
97 INT800 Negative_regulation of Grhpr 21 0.42 10.3 7.17 5.00
98 INT93003 Binding of CD40 28 0.47 20.25 7.13 5.00
99 INT36053 Positive_regulation of Positive_regulation of IL1B 22 0.70 11.41 6.84 5.00
100 INT171749 Positive_regulation of Gene_expression of CXCR3 18 0.58 11.03 6.51 5.00
101 INT103260 Positive_regulation of Nps 35 0.48 23.8 5.67 5.00
102 INT3163 Gene_expression of NAGLU 28 0.75 15.23 4.98 5.00
103 INT83680 Gene_expression of FUT1 40 0.26 25.45 4.98 5.00
104 INT16214 Localization of F13A1 36 0.74 21.8 4.87 5.00
105 INT12324 Positive_regulation of PRTN3 26 0.70 18.82 4.55 5.00
106 INT170738 Binding of Icam1 23 0.37 25.49 4.09 5.00
107 INT22838 Gene_expression of Fgg 26 0.25 19.9 3.88 5.00
108 INT28060 Positive_regulation of Hdlcl1 48 0.66 37.31 3.79 5.00
109 INT159472 Localization of NPPB 32 0.79 33.67 3.59 5.00
110 INT131877 Negative_regulation of Nps 12 0.39 8.19 3.56 5.00
111 INT137180 Binding of CXCR3 10 0.41 4.24 3.53 5.00
112 INT32453 Positive_regulation of Gene_expression of Ptafr 2 0.58 7.01 3.47 5.00
113 INT237054 Negative_regulation of Gene_expression of Cxcl10 11 0.56 10.26 3.4 5.00
114 INT207449 Negative_regulation of OLR1 23 0.42 17.17 3.37 5.00
115 INT182233 Gene_expression of CCR4 14 0.43 6.55 3.31 5.00
116 INT70958 Binding of NOS3 19 0.37 11.84 3.29 5.00
117 INT9884 Localization of CD79A 41 0.78 21.75 3.06 5.00
118 INT226178 Gene_expression of thd 14 0.23 8.29 2.92 5.00
119 INT77602 Binding of VCAM1 8 0.41 8.66 2.86 5.00
120 INT45272 Regulation of Nps 15 0.39 8.08 2.69 5.00
121 INT155889 Binding of Nps 22 0.42 9.79 2.6 5.00
122 INT39407 Binding of OLR1 18 0.48 14.79 2.51 5.00
123 INT145101 Transcription of Nos3 8 0.70 6.04 2.47 5.00
124 INT5180 Binding of Serpinc1 27 0.36 13.39 2.47 5.00
125 INT105993 Gene_expression of IDS 26 0.78 10.83 2.41 5.00
126 INT150476 Positive_regulation of ELF3 32 0.56 13.61 2.39 5.00
127 INT205683 Localization of Ptafr 4 0.12 4.63 2.31 5.00
128 INT73809 Regulation of Nos3 18 0.45 10.05 2.27 5.00
129 INT28739 Binding of Ins1 35 0.37 22.43 2.14 5.00
130 INT39453 Negative_regulation of TCN2 12 0.59 3.98 2.13 5.00
131 INT68829 Binding of ELF3 14 0.47 7.96 2 5.00
132 INT84264 Regulation of NPPB 22 0.61 21.18 1.94 5.00
133 INT52965 Negative_regulation of TNXA 18 0.43 8.38 1.9 5.00
134 INT194074 Regulation of NAGLU 5 0.38 2.93 1.87 5.00
135 INT66930 Positive_regulation of Tcirg1 2 0.15 1.18 1.6 5.00
136 INT223091 Gene_expression of ELF3 45 0.62 17.9 1.56 5.00
137 INT237862 Positive_regulation of Gene_expression of Nps 8 0.43 3.82 1.52 5.00
138 INT81224 Negative_regulation of Ado 3 0.29 1.28 1.46 5.00
139 INT226175 Regulation of thd 8 0.14 6.8 1.42 5.00
140 INT187411 Gene_expression of Cd320 23 0.75 12.1 1.39 5.00
141 INT62896 Binding of NOSTRIN 4 0.30 2.86 1.3 5.00
142 INT102845 Localization of CASP3 7 0.81 2.81 1.06 5.00
143 INT98992 Binding of Vcam1 13 0.34 12.97 1.04 5.00
144 INT217341 Negative_regulation of Gene_expression of CXCL10 6 0.25 4.97 1.04 5.00
145 INT200462 Binding of IDS 13 0.31 4.95 1 5.00
146 INT80296 Gene_expression of CCL7 4 0.43 1.65 0.93 5.00
147 INT23921 Negative_regulation of NPPB 13 0.58 16.19 0.9 5.00
148 INT93899 Negative_regulation of Tcirg1 5 0.14 4.34 0.85 5.00
149 INT111199 Gene_expression of Acly 11 0.16 5.65 0.78 5.00
150 INT238903 Negative_regulation of Gene_expression of OLR1 4 0.41 3.18 0.77 5.00
151 INT211907 Gene_expression of RIOK3 3 0.13 3.96 0.75 5.00
152 INT237866 Positive_regulation of Positive_regulation of Nps 5 0.48 2.67 0.69 5.00
153 INT211906 Gene_expression of EPC1 15 0.19 3.75 0.61 5.00
154 INT157226 Positive_regulation of Gene_expression of Tnnc1 11 0.49 6.21 0.57 5.00
155 INT236648 Binding of Hrt1 4 0.07 5.07 0.51 5.00
156 INT43091 Positive_regulation of Negative_regulation of Ace 3 0.30 1.51 0.48 5.00
157 INT211905 Negative_regulation of RIOK3 2 0.07 2.25 0.48 5.00
158 INT189852 Localization of H2-Q13 4 0.06 4.1 0.47 5.00
159 INT145100 Regulation of Transcription of Nos3 4 0.44 2.05 0.46 5.00
160 INT174817 Localization of IL16 2 0.72 2.8 0.45 5.00
161 INT22837 Regulation of Fgg 2 0.10 1.87 0.41 5.00
162 INT72717 Gene_expression of Nppc 8 0.51 6.25 0.39 5.00
163 INT342465 Protein_catabolism of MRI1 1 0.04 0.79 0.38 5.00
164 INT130344 Gene_expression of APOH 3 0.34 2.87 0.32 5.00
165 INT334041 Gene_expression of Cdt1 5 0.29 2.69 0.32 5.00
166 INT208468 Binding of IL16 2 0.42 2.3 0.29 5.00
167 INT176895 Negative_regulation of EEF1A2 3 0.41 0.85 0.29 5.00
168 INT149141 Negative_regulation of Skap2 3 0.34 0.43 0.25 5.00
169 INT151978 Negative_regulation of Positive_regulation of Cys1 3 0.41 4.15 0.24 5.00
170 INT208470 Negative_regulation of IL16 1 0.41 2.41 0.2 5.00
171 INT219022 Positive_regulation of IgM 1:10240 1 0.01 1.44 0.16 5.00
172 INT192194 Positive_regulation of FBXW11 3 0.34 0.84 0.14 5.00
173 INT316238 Localization of Tcirg1 2 0.30 1.98 0.14 5.00
174 INT208464 Protein_catabolism of IL16 1 0.55 0.93 0.13 5.00
175 INT316240 Regulation of Tcirg1 2 0.16 2.05 0.13 5.00
176 INT327770 Binding of Tcirg1 1 0.14 1.65 0.12 5.00
177 INT323218 Gene_expression of ZC3H15 1 0.05 2.59 0.07 5.00
178 INT342463 Positive_regulation of CRTC1 1 0.01 0.57 0.06 5.00
179 INT168933 Positive_regulation of Car5b 2 0.15 0.64 0.05 5.00
180 INT323219 Positive_regulation of ZC3H15 1 0.04 1.09 0.04 5.00
181 INT323215 Regulation of Binding of ZC3H15 1 0.03 0.99 0 5.00
182 INT228302 Transcription of 16S 3 0.67 0.08 0 5.00
183 INT296884 Negative_regulation of Negative_regulation of NPPB 1 0.01 1.37 0 5.00
184 INT323214 Regulation of ZC3H15 1 0.02 0.29 0 5.00
185 INT323216 Localization of ZC3H15 1 0.06 0.1 0 5.00
186 INT323220 Transcription of ZC3H15 1 0.04 0.95 0 5.00
187 INT223092 Negative_regulation of AP2S1 1 0.01 0.72 0 5.00
188 INT223093 Phosphorylation of NAGLU 1 0.45 0.95 0 5.00
189 INT187736 Positive_regulation of Rapsn 1 0.17 0.3 0 5.00
190 INT86569 Gene_expression of AP2S1 2 0.15 0.55 0 5.00
191 INT208466 Positive_regulation of Localization of CASP3 1 0.01 0.98 0 5.00
192 INT323217 Binding of ZC3H15 1 0.03 0.98 0 5.00
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